BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
3775	Nc1ncnc2n(nc(-c3ccccc3)c12)-c1ccccc1	InChI=1S/C17H13N5/c18-16-14-15(12-7-3-1-4-8-12)21-22(17(14)20-11-19-16)13-9-5-2-6-10-13/h1-11H,(H2,18,19,20)	CGWOMXNQGSNOHL-UHFFFAOYSA-N	3003	1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (11)::CHEMBL122243::pyrazolopyrimidine deriv. 1	Epidermal growth factor receptor	Homo sapiens		 800					7.5000	20.00 C	Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3003&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327820	8032750		CHEMBL122243					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3776	Nc1nc(N)c2c(Nc3cccc(Cl)c3)[nH]nc2n1	InChI=1S/C11H10ClN7/c12-5-2-1-3-6(4-5)15-9-7-8(13)16-11(14)17-10(7)19-18-9/h1-4H,(H6,13,14,15,16,17,18,19)	YASYSLUSCVNMAJ-UHFFFAOYSA-N	3004	3-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4,6-triamine::3-((3-Chlorophenyl)amino)-4,6-diamino-1H-pyrazolo[3,4-d]pyrimidine::pyrazolopyrimidine deriv. 2	Epidermal growth factor receptor	Homo sapiens		 220					7.5000	20.00 C	Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3004&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327821	8032751							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3777	Nc1ncnc2n[nH]c(Nc3cccc(Cl)c3)c12	InChI=1S/C11H9ClN6/c12-6-2-1-3-7(4-6)16-11-8-9(13)14-5-15-10(8)17-18-11/h1-5H,(H4,13,14,15,16,17,18)	ZDNMTYMNWKRHQA-UHFFFAOYSA-N	3005	3-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((3-Chlorophenyl)amino)-4-amino-1H-pyrazolo[3,4-d]pyrimidine::pyrazolopyrimidine deriv. 6	Epidermal growth factor receptor	Homo sapiens		 160					7.5000	20.00 C	Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3005	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3005&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327822	8032752							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3778	N(c1[nH]nc2ncnc(Nc3ccccc3)c12)c1ccccc1	InChI=1S/C17H14N6/c1-3-7-12(8-4-1)20-15-14-16(19-11-18-15)22-23-17(14)21-13-9-5-2-6-10-13/h1-11H,(H3,18,19,20,21,22,23)	IZWVMBDZDRQDDZ-UHFFFAOYSA-N	3006	3,4-Di-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidine::3-N,4-N-diphenyl-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 7	Epidermal growth factor receptor	Homo sapiens		 58					7.5000	20.00 C	Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3006&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327823	8032753							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3779	Clc1cccc(Nc2[nH]nc3ncnc(Nc4ccccc4)c23)c1	InChI=1S/C17H13ClN6/c18-11-5-4-8-13(9-11)22-17-14-15(19-10-20-16(14)23-24-17)21-12-6-2-1-3-7-12/h1-10H,(H3,19,20,21,22,23,24)	XCZCKVIRXXMKJC-UHFFFAOYSA-N	3007	3-N-(3-chlorophenyl)-4-N-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((3-Chlorophenyl)amino)-4-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 8	Epidermal growth factor receptor	Homo sapiens		 84					7.5000	20.00 C	Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3007&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327824	8032754							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3780	Clc1cccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1	InChI=1S/C17H12Cl2N6/c18-10-3-1-5-12(7-10)22-15-14-16(21-9-20-15)24-25-17(14)23-13-6-2-4-11(19)8-13/h1-9H,(H3,20,21,22,23,24,25)	URVRJEIGGRSCLI-UHFFFAOYSA-N	3008	3-N,4-N-bis(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3,4-Bis((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 9	Epidermal growth factor receptor	Homo sapiens		 33					7.5000	20.00 C	Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3008&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327825	8032755							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3807	Clc1cccc(Nc2[nH]nc3ncnc(Nc4cccc(Br)c4)c23)c1	InChI=1S/C17H12BrClN6/c18-10-3-1-5-12(7-10)22-15-14-16(21-9-20-15)24-25-17(14)23-13-6-2-4-11(19)8-13/h1-9H,(H3,20,21,22,23,24,25)	JUKRBPQFJFOIDS-UHFFFAOYSA-N	3009	4-N-(3-bromophenyl)-3-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((3-Chlorophenyl)amino)-4-((3-bromophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 10	Epidermal growth factor receptor	Homo sapiens		 130							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3009	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3009&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327826	8032756							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3808	Cc1cccc(Nc2ncnc3n[nH]c(Nc4cccc(Cl)c4)c23)c1	InChI=1S/C18H15ClN6/c1-11-4-2-6-13(8-11)22-16-15-17(21-10-20-16)24-25-18(15)23-14-7-3-5-12(19)9-14/h2-10H,1H3,(H3,20,21,22,23,24,25)	PLZVTPONFFMTDM-UHFFFAOYSA-N	3010	3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::3-N-(3-chlorophenyl)-4-N-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 11	Epidermal growth factor receptor	Homo sapiens		 130							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3010&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327827	8032757							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3809	COc1ccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1	InChI=1S/C18H15ClN6O/c1-26-14-7-5-12(6-8-14)22-18-15-16(20-10-21-17(15)24-25-18)23-13-4-2-3-11(19)9-13/h2-10H,1H3,(H3,20,21,22,23,24,25)	DVTLAQZTCJXBPC-UHFFFAOYSA-N	3011	4-N-(3-chlorophenyl)-3-N-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((4-Methoxyphenyl)-amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 12	Epidermal growth factor receptor	Homo sapiens		 30							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3011&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327828	8032758							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3810	Oc1ccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1	InChI=1S/C17H13ClN6O/c18-10-2-1-3-12(8-10)22-15-14-16(20-9-19-15)23-24-17(14)21-11-4-6-13(25)7-5-11/h1-9,25H,(H3,19,20,21,22,23,24)	DBDQLLPCPIODHI-UHFFFAOYSA-N	3012	4-({4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}amino)phenol::3-((4-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 13	Epidermal growth factor receptor	Homo sapiens		 8							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3012&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327829	8032759							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3819	COc1cccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1	InChI=1S/C18H15ClN6O/c1-26-14-7-3-6-13(9-14)23-18-15-16(20-10-21-17(15)24-25-18)22-12-5-2-4-11(19)8-12/h2-10H,1H3,(H3,20,21,22,23,24,25)	ABEGFBRZNZWQBS-UHFFFAOYSA-N	3013	4-N-(3-chlorophenyl)-3-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((3-Methoxyphenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 14	Epidermal growth factor receptor	Homo sapiens		 8							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3013&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327830	8032760							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3820	Oc1cccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1	InChI=1S/C17H13ClN6O/c18-10-3-1-4-11(7-10)21-15-14-16(20-9-19-15)23-24-17(14)22-12-5-2-6-13(25)8-12/h1-9,25H,(H3,19,20,21,22,23,24)	BUGPWXMPCMTLIX-UHFFFAOYSA-N	3014	3-({4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}amino)phenol::3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 15	Epidermal growth factor receptor	Homo sapiens		 1							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3014&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327831	8032761							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3821	CC(C)(C)OC(=O)Nc1ccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1	InChI=1S/C22H22ClN7O2/c1-22(2,3)32-21(31)28-15-9-7-14(8-10-15)26-20-17-18(24-12-25-19(17)29-30-20)27-16-6-4-5-13(23)11-16/h4-12H,1-3H3,(H,28,31)(H3,24,25,26,27,29,30)	UJPPYLLBYAYYPH-UHFFFAOYSA-N	3015	tert-butyl N-[4-({4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}amino)phenyl]carbamate::3-((4-(N-BOC-amino)phenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 16	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3015&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327832	8032762							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3822	Nc1ccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1	InChI=1S/C17H14ClN7/c18-10-2-1-3-13(8-10)23-15-14-16(21-9-20-15)24-25-17(14)22-12-6-4-11(19)5-7-12/h1-9H,19H2,(H3,20,21,22,23,24,25)	KMXFOTQAKQWIOA-UHFFFAOYSA-N	3016	3-N-(4-aminophenyl)-4-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 17	Epidermal growth factor receptor	Homo sapiens		 5							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3016&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327833	8032763							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3839	CN(C)c1ccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1	InChI=1S/C19H18ClN7/c1-27(2)15-8-6-13(7-9-15)23-19-16-17(21-11-22-18(16)25-26-19)24-14-5-3-4-12(20)10-14/h3-11H,1-2H3,(H3,21,22,23,24,25,26)	DBMNQXNYFIEZLF-UHFFFAOYSA-N	3017	3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-N-(3-chlorophenyl)-3-N-[4-(dimethylamino)phenyl]-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 18	Epidermal growth factor receptor	Homo sapiens		 29							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3017&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327834	8032764							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3840	Clc1cccc(Nc2ncnc3n[nH]c(NCc4ccccc4)c23)c1	InChI=1S/C18H15ClN6/c19-13-7-4-8-14(9-13)23-16-15-17(24-25-18(15)22-11-21-16)20-10-12-5-2-1-3-6-12/h1-9,11H,10H2,(H3,20,21,22,23,24,25)	BEXPELAOVIOQHQ-UHFFFAOYSA-N	3018	3-(Benzylamino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::3-N-benzyl-4-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 19	Epidermal growth factor receptor	Homo sapiens		 7							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3018	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3018&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327835	8032765							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3841	Clc1cccc(CNc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1	InChI=1S/C18H14Cl2N6/c19-12-4-1-3-11(7-12)9-21-17-15-16(22-10-23-18(15)26-25-17)24-14-6-2-5-13(20)8-14/h1-8,10H,9H2,(H3,21,22,23,24,25,26)	QFEGUXCVHFPAEW-UHFFFAOYSA-N	3019	4-N-(3-chlorophenyl)-3-N-[(3-chlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((3-Chlorobenzyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 20	Epidermal growth factor receptor	Homo sapiens		 26							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3019&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327836	8032766							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3842	COc1cccc(CNc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1	InChI=1S/C19H17ClN6O/c1-27-15-7-2-4-12(8-15)10-21-18-16-17(22-11-23-19(16)26-25-18)24-14-6-3-5-13(20)9-14/h2-9,11H,10H2,1H3,(H3,21,22,23,24,25,26)	ASEKFENKLHTYMI-UHFFFAOYSA-N	3020	3-((3-Methoxybenzyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-N-(3-chlorophenyl)-3-N-[(3-methoxyphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 21	Epidermal growth factor receptor	Homo sapiens		 8							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3020	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3020&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327837	8032767							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3859	COc1ccc(CNc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1	InChI=1S/C19H17ClN6O/c1-27-15-7-5-12(6-8-15)10-21-18-16-17(22-11-23-19(16)26-25-18)24-14-4-2-3-13(20)9-14/h2-9,11H,10H2,1H3,(H3,21,22,23,24,25,26)	KGHAUONMJSXUDW-UHFFFAOYSA-N	3021	3-((4-Methoxybenzyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-N-(3-chlorophenyl)-3-N-[(4-methoxyphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 22	Epidermal growth factor receptor	Homo sapiens		 7							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3021&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327838	8032768							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3860	Clc1cccc(Nc2ncnc3n[nH]c(-c4ccccc4)c23)c1	InChI=1S/C17H12ClN5/c18-12-7-4-8-13(9-12)21-16-14-15(11-5-2-1-3-6-11)22-23-17(14)20-10-19-16/h1-10H,(H2,19,20,21,22,23)	JBHXXYIRQFVFOU-UHFFFAOYSA-N	3022	N-(3-chlorophenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 23	Epidermal growth factor receptor	Homo sapiens		 19							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3022&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327839	8032769							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3861	Oc1cccc(c1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12	InChI=1S/C17H12ClN5O/c18-11-4-2-5-12(8-11)21-16-14-15(10-3-1-6-13(24)7-10)22-23-17(14)20-9-19-16/h1-9,24H,(H2,19,20,21,22,23)	DVMBLTDKHALLLH-UHFFFAOYSA-N	3023	3-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}phenol::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 24	Epidermal growth factor receptor	Homo sapiens		 26							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3023&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327840	8032770							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3862	COc1ccc(cc1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12	InChI=1S/C18H14ClN5O/c1-25-14-7-5-11(6-8-14)16-15-17(20-10-21-18(15)24-23-16)22-13-4-2-3-12(19)9-13/h2-10H,1H3,(H2,20,21,22,23,24)	CNEAVADKWYPXBR-UHFFFAOYSA-N	3024	3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::N-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 25	Epidermal growth factor receptor	Homo sapiens		 96							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3024&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327841	8032771							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3879	Oc1ccc(cc1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12	InChI=1S/C17H12ClN5O/c18-11-2-1-3-12(8-11)21-16-14-15(10-4-6-13(24)7-5-10)22-23-17(14)20-9-19-16/h1-9,24H,(H2,19,20,21,22,23)	DTGDQRLXHBUCRM-UHFFFAOYSA-N	3025	4-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}phenol::3-(4-Hydroxyphenyl)-4-((3-chlorophenyl)amino)pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 26	Epidermal growth factor receptor	Homo sapiens		 6							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3025&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327842	8032772							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3880	[O-][N+](=O)c1cccc(c1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12	InChI=1S/C17H11ClN6O2/c18-11-4-2-5-12(8-11)21-16-14-15(22-23-17(14)20-9-19-16)10-3-1-6-13(7-10)24(25)26/h1-9H,(H2,19,20,21,22,23)	BJCWVHPCCLIDDY-UHFFFAOYSA-N	3026	3-(3-Nitrophenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::N-(3-chlorophenyl)-3-(3-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 27	Epidermal growth factor receptor	Homo sapiens		 37							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3026	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3026&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327843	8032773							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3881	Nc1cccc(c1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12	InChI=1S/C17H13ClN6/c18-11-4-2-6-13(8-11)22-16-14-15(10-3-1-5-12(19)7-10)23-24-17(14)21-9-20-16/h1-9H,19H2,(H2,20,21,22,23,24)	WXPDCELKHNMODS-UHFFFAOYSA-N	3027	3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::3-(3-aminophenyl)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 28	Epidermal growth factor receptor	Homo sapiens		 5							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3027&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327844	8032774							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3882	CC(C)(C)OC(=O)Nc1ccc(cc1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12	InChI=1S/C22H21ClN6O2/c1-22(2,3)31-21(30)27-15-9-7-13(8-10-15)18-17-19(24-12-25-20(17)29-28-18)26-16-6-4-5-14(23)11-16/h4-12H,1-3H3,(H,27,30)(H2,24,25,26,28,29)	FDHOXGIXMNBPSE-UHFFFAOYSA-N	3028	3-(4-(BOC-amino)phenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::tert-butyl N-(4-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}phenyl)carbamate::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 29	Epidermal growth factor receptor	Homo sapiens		 270							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3028&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327845	8032775							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3899	Nc1ccc(cc1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12	InChI=1S/C17H13ClN6/c18-11-2-1-3-13(8-11)22-16-14-15(10-4-6-12(19)7-5-10)23-24-17(14)21-9-20-16/h1-9H,19H2,(H2,20,21,22,23,24)	BXQSENVZNNEEBV-UHFFFAOYSA-N	3029	3-(4-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine Hydrochloride::3-(4-aminophenyl)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 30	Epidermal growth factor receptor	Homo sapiens		 2							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3029	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3029&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327846	8032776							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3900	Clc1cccc(Nc2[nH]nc3ncnc(Oc4cccc(Cl)c4)c23)c1	InChI=1S/C17H11Cl2N5O/c18-10-3-1-5-12(7-10)22-16-14-15(23-24-16)20-9-21-17(14)25-13-6-2-4-11(19)8-13/h1-9H,(H2,20,21,22,23,24)	PDMAVKGRERGACM-UHFFFAOYSA-N	3030	4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 31	Epidermal growth factor receptor	Homo sapiens		 24200							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3030&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327847	8032777							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3901	Clc1cccc(Nc2[nH]nc3ncnc(NCc4ccccc4)c23)c1	InChI=1S/C18H15ClN6/c19-13-7-4-8-14(9-13)23-18-15-16(21-11-22-17(15)24-25-18)20-10-12-5-2-1-3-6-12/h1-9,11H,10H2,(H3,20,21,22,23,24,25)	LRHDXMDHHMEKIP-UHFFFAOYSA-N	3031	4-N-benzyl-3-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 32	Epidermal growth factor receptor	Homo sapiens		 870							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3031&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327848	8032778							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
3902	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	LSPANGZZENHZNJ-UHFFFAOYSA-N	3032	CHEMBL29197::N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL1204168::PD153035::US9422297, PD153035::US11111252, Compound PD153035::US11001595, Compound PD153035	Epidermal growth factor receptor	Homo sapiens		 6							Curated from the literature by BindingDB	10.1021/jm970124v	10.7270/Q2H70D0N	9357527	aid1795439		Traxler, P; Bold, G; Frei, J; Lang, M; Lydon, N; Mett, H; Buchdunger, E; Meyer, T; Mueller, M; Furet, P	10/24/1997	1/11/2005	Novartis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3032&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4705	8032779		CHEMBL1204168CHEMBL29197					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4005	Cn1c2nc(N)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C14H10Cl2N4O/c1-20-12-7(6-18-14(17)19-12)5-8(13(20)21)11-9(15)3-2-4-10(11)16/h2-6H,1H3,(H2,17,18,19)	CWCLGIJGJSHBLC-UHFFFAOYSA-N	3050	2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one::CHEMBL49596::2-amino-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 2	Epidermal growth factor receptor	Homo sapiens		 5600					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3050	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3050&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327864	8032797		CHEMBL49596					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4006	CNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,)|	InChI=1S/C15H12Cl2N4O/c1-18-15-19-7-8-6-9(14(22)21(2)13(8)20-15)12-10(16)4-3-5-11(12)17/h3-7H,1-2H3,(H,18,19,20)	UZGZLCVPKWOCDZ-UHFFFAOYSA-N	3054	6-(2,6-Dichlorophenyl)-8-methyl-2-methylamino-8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::6-(2,6-dichlorophenyl)-8-methyl-2-(methylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 21	Epidermal growth factor receptor	Homo sapiens		 7500					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3054&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327868	8032801							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4007	CCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-9.48,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,)|	InChI=1S/C16H14Cl2N4O/c1-3-19-16-20-8-9-7-10(15(23)22(2)14(9)21-16)13-11(17)5-4-6-12(13)18/h4-8H,3H2,1-2H3,(H,19,20,21)	FNBJMQJWFBTPGJ-UHFFFAOYSA-N	3055	PD 166285 analog::6-(2,6-dichlorophenyl)-2-(ethylamino)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 22	Epidermal growth factor receptor	Homo sapiens		 4500					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3055&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327869	8032802							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4023	CC(C)Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-9.48,-2.74,;-8.15,-1.97,;-6.82,-2.74,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,)|	InChI=1S/C17H16Cl2N4O/c1-9(2)21-17-20-8-10-7-11(16(24)23(3)15(10)22-17)14-12(18)5-4-6-13(14)19/h4-9H,1-3H3,(H,20,21,22)	GWRZAKQWUQRPDF-UHFFFAOYSA-N	3056	6-(2,6-dichlorophenyl)-8-methyl-2-(propan-2-ylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 23	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3056&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327870	8032803							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4024	CCCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-6.5,-5.16,;-7.59,-4.08,;-6.82,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,)|	InChI=1S/C18H18Cl2N4O/c1-3-4-8-21-18-22-10-11-9-12(17(25)24(2)16(11)23-18)15-13(19)6-5-7-14(15)20/h5-7,9-10H,3-4,8H2,1-2H3,(H,21,22,23)	QOSLUZXSYUGPOU-UHFFFAOYSA-N	3057	2-(butylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 24	Epidermal growth factor receptor	Homo sapiens		 4400							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3057&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327871	8032804							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4025	Cn1c2nc(NC3CCCCC3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.81,-2.74,;-6.81,-4.28,;-8.14,-5.05,;-9.48,-4.29,;-9.48,-2.75,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H20Cl2N4O/c1-26-18-12(11-23-20(25-18)24-13-6-3-2-4-7-13)10-14(19(26)27)17-15(21)8-5-9-16(17)22/h5,8-11,13H,2-4,6-7H2,1H3,(H,23,24,25)	SPPVVBKDFLCZFT-UHFFFAOYSA-N	3058	2-Cyclohexylamino-6-(2,6-dichlorophenyl)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one::2-(cyclohexylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 25	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3058&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327872	8032805							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4026	Cn1c2nc(NCCO)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-9.48,-2.75,;-9.88,-4.23,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C16H14Cl2N4O2/c1-22-14-9(8-20-16(21-14)19-5-6-23)7-10(15(22)24)13-11(17)3-2-4-12(13)18/h2-4,7-8,23H,5-6H2,1H3,(H,19,20,21)	GOWKLVGETIDUTE-UHFFFAOYSA-N	3059	PD 166285 analog::6-(2,6-dichlorophenyl)-2-[(2-hydroxyethyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 26	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3059&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327873	8032806							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4027	Cn1c2nc(NCc3ccccc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-9.48,-2.74,;-10.82,-1.97,;-12.15,-2.74,;-12.15,-4.28,;-10.82,-5.05,;-9.48,-4.28,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C21H16Cl2N4O/c1-27-19-14(10-15(20(27)28)18-16(22)8-5-9-17(18)23)12-25-21(26-19)24-11-13-6-3-2-4-7-13/h2-10,12H,11H2,1H3,(H,24,25,26)	GCVONYYXPDJZOE-UHFFFAOYSA-N	3060	2-(benzylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 27	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3060&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327874	8032807							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4043	CN(C)c1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-8.15,-1.97,;-8.15,-.43,;-9.48,.34,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,)|	InChI=1S/C16H14Cl2N4O/c1-21(2)16-19-8-9-7-10(15(23)22(3)14(9)20-16)13-11(17)5-4-6-12(13)18/h4-8H,1-3H3	JBLZRKIIUFHPCO-UHFFFAOYSA-N	3061	6-(2,6-dichlorophenyl)-2-(dimethylamino)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL299347::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 28	Epidermal growth factor receptor	Homo sapiens		 50000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3061&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327875	8032808		CHEMBL299347					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4044	CCN(CC)CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-6.72,-6.82,;-8.2,-7.22,;-9.29,-6.13,;-10.38,-7.22,;-11.71,-6.45,;-8.52,-4.79,;-8.92,-3.31,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,)|	InChI=1S/C21H25Cl2N5O/c1-4-28(5-2)11-7-10-24-21-25-13-14-12-15(20(29)27(3)19(14)26-21)18-16(22)8-6-9-17(18)23/h6,8-9,12-13H,4-5,7,10-11H2,1-3H3,(H,24,25,26)	NZHAVEPSCYGCPU-UHFFFAOYSA-N	3062	6-(2,6-dichlorophenyl)-2-{[3-(diethylamino)propyl]amino}-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::[6-(2,6-Dichlorophenyl)-8-methyl-7-oxo-7,8-dihydropyrido-[2,3-d]pyrimidin-2-yl]-(3-diethylaminopropyl)amine::CHEMBL50470::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 29	Epidermal growth factor receptor	Homo sapiens		 1400							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3062&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327876	8032809		CHEMBL50470					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4045	Cn1c2nc(NCCCN3CCOCC3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-8.92,-3.31,;-8.52,-4.79,;-9.18,-6.13,;-8.09,-7.22,;-8.49,-8.7,;-9.97,-9.1,;-11.06,-8.01,;-10.66,-6.53,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C21H23Cl2N5O2/c1-27-19-14(12-15(20(27)29)18-16(22)4-2-5-17(18)23)13-25-21(26-19)24-6-3-7-28-8-10-30-11-9-28/h2,4-5,12-13H,3,6-11H2,1H3,(H,24,25,26)	CSLJSOAIJCEXMF-UHFFFAOYSA-N	3063	PD 166285 analog::6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(morpholin-4-yl)propyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::6-(2,6-Dichlorophenyl)-8-methyl-2-(3-morpholin-4-ylpropylamino)-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL48172::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 30	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3063&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327877	8032810		CHEMBL48172					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4046	CN1CCN(CCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)CC1 |(-10.37,-10.59,;-9.97,-9.1,;-8.49,-8.7,;-8.09,-7.22,;-9.18,-6.13,;-8.52,-4.79,;-8.92,-3.31,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-10.66,-6.53,;-11.06,-8.01,)|	InChI=1S/C22H26Cl2N6O/c1-28-9-11-30(12-10-28)8-4-7-25-22-26-14-15-13-16(21(31)29(2)20(15)27-22)19-17(23)5-3-6-18(19)24/h3,5-6,13-14H,4,7-12H2,1-2H3,(H,25,26,27)	NZUXTCRYWPXTJA-UHFFFAOYSA-N	3064	CHEMBL299194::PD 166285 analog::6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(4-methylpiperazin-1-yl)propyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31	Epidermal growth factor receptor	Homo sapiens		 8700							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3064&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327878	8032811		CHEMBL299194					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4047	CN1CCN(CCCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)CC1 |(-8.54,-12.22,;-8.54,-10.68,;-7.27,-9.81,;-7.39,-8.28,;-8.78,-7.61,;-9.18,-6.13,;-8.52,-4.79,;-8.92,-3.31,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-10.05,-8.49,;-9.93,-10.02,)|	InChI=1S/C23H28Cl2N6O/c1-29-10-12-31(13-11-29)9-4-3-8-26-23-27-15-16-14-17(22(32)30(2)21(16)28-23)20-18(24)6-5-7-19(20)25/h5-7,14-15H,3-4,8-13H2,1-2H3,(H,26,27,28)	QCDZPARUOUZGLL-UHFFFAOYSA-N	3065	6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(4-methylpiperazin-1-yl)butyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::6-(2,6-Dichlorophenyl)-8-methyl-2-[4-(4-methylpiperazin-1-yl)butylamino]-8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 32	Epidermal growth factor receptor	Homo sapiens		 210							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3065&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327879	8032812							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4063	CN1CCN(CCCCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)CC1 |(-9.18,-13.72,;-9.18,-12.18,;-7.84,-11.41,;-7.84,-9.87,;-9.18,-9.1,;-8.78,-7.61,;-9.18,-6.13,;-8.52,-4.79,;-8.92,-3.31,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-10.51,-9.87,;-10.51,-11.41,)|	InChI=1S/C24H30Cl2N6O/c1-30-11-13-32(14-12-30)10-5-3-4-9-27-24-28-16-17-15-18(23(33)31(2)22(17)29-24)21-19(25)7-6-8-20(21)26/h6-8,15-16H,3-5,9-14H2,1-2H3,(H,27,28,29)	NMLMUNQQEDDASM-UHFFFAOYSA-N	3066	6-(2,6-dichlorophenyl)-8-methyl-2-{[5-(4-methylpiperazin-1-yl)pentyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 33	Epidermal growth factor receptor	Homo sapiens		 4500							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3066	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3066&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327880	8032813							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4064	Cn1c2nc(NCc3ccccn3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-8.92,-3.31,;-10.45,-3.09,;-11.4,-4.3,;-10.82,-5.73,;-9.3,-5.95,;-8.35,-4.73,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H15Cl2N5O/c1-27-18-12(9-14(19(27)28)17-15(21)6-4-7-16(17)22)10-24-20(26-18)25-11-13-5-2-3-8-23-13/h2-10H,11H2,1H3,(H,24,25,26)	UVQZXQCNEXGALO-UHFFFAOYSA-N	3067	PD 166285 analog::6-(2,6-dichlorophenyl)-8-methyl-2-[(pyridin-2-ylmethyl)amino]-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 34	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3067&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327881	8032814							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4065	Cn1c2nc(NCc3cccnc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-8.92,-3.31,;-10.46,-3.31,;-11.23,-4.64,;-10.46,-5.97,;-8.92,-5.97,;-8.15,-4.64,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H15Cl2N5O/c1-27-18-13(8-14(19(27)28)17-15(21)5-2-6-16(17)22)11-25-20(26-18)24-10-12-4-3-7-23-9-12/h2-9,11H,10H2,1H3,(H,24,25,26)	XHGSDPKRXJOFGF-UHFFFAOYSA-N	3068	6-(2,6-dichlorophenyl)-8-methyl-2-[(pyridin-3-ylmethyl)amino]-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 35	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3068&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327882	8032815							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4066	Cn1c2nc(NCCc3ccccn3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-8.92,-3.31,;-8.15,-4.64,;-8.9,-5.99,;-8.1,-7.31,;-6.56,-7.28,;-5.82,-5.93,;-6.61,-4.61,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C21H17Cl2N5O/c1-28-19-13(11-15(20(28)29)18-16(22)6-4-7-17(18)23)12-26-21(27-19)25-10-8-14-5-2-3-9-24-14/h2-7,9,11-12H,8,10H2,1H3,(H,25,26,27)	NRYIWRROVMCMDV-UHFFFAOYSA-N	3069	6-(2,6-dichlorophenyl)-8-methyl-2-{[2-(pyridin-2-yl)ethyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 36	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3069	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3069&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327883	8032816							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4067	Cn1c2nc(NCCCCCC(O)=O)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-8.92,-3.31,;-8.15,-4.64,;-8.92,-5.97,;-8.52,-7.46,;-9.61,-8.55,;-9.61,-10.09,;-10.94,-7.78,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H20Cl2N4O3/c1-26-18-12(10-13(19(26)29)17-14(21)6-5-7-15(17)22)11-24-20(25-18)23-9-4-2-3-8-16(27)28/h5-7,10-11H,2-4,8-9H2,1H3,(H,27,28)(H,23,24,25)	GWLRNLPJEBRBCZ-UHFFFAOYSA-N	3070	PD 166285 analog::6-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl]amino}hexanoic acid::6-[6-(2,6-Dichlorophenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino]hexanoic acid, Trifluoroacetic Acid Salt::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 37	Epidermal growth factor receptor	Homo sapiens		 1000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3070	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3070&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327884	8032817							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4083	Cn1c2nc(Nc3ccccc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.81,-2.74,;-6.81,-4.28,;-8.14,-5.05,;-9.48,-4.29,;-9.48,-2.75,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H14Cl2N4O/c1-26-18-12(11-23-20(25-18)24-13-6-3-2-4-7-13)10-14(19(26)27)17-15(21)8-5-9-16(17)22/h2-11H,1H3,(H,23,24,25)	MACKJBHSMLAAGO-UHFFFAOYSA-N	3071	2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one::CHEMBL301612::PD 166285 analog::6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 38	Epidermal growth factor receptor	Homo sapiens		 260							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3071	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3071&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327885	8032818		CHEMBL301612					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4084	CCn1c2nc(Nc3ccccc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-1.73,-3.06,;-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.81,-2.74,;-6.81,-4.28,;-8.14,-5.05,;-9.48,-4.29,;-9.48,-2.75,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C21H16Cl2N4O/c1-2-27-19-13(12-24-21(26-19)25-14-7-4-3-5-8-14)11-15(20(27)28)18-16(22)9-6-10-17(18)23/h3-12H,2H2,1H3,(H,24,25,26)	XZBKAAPFQAVYSN-UHFFFAOYSA-N	3072	PD 166285 analog::6-(2,6-dichlorophenyl)-8-ethyl-2-(phenylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 39	Epidermal growth factor receptor	Homo sapiens		 200							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3072	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3072&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327886	8032819							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4085	Cn1c2nc(Nc3cccnc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-9.48,-2.74,;-9.48,-4.28,;-8.15,-5.05,;-6.82,-4.28,;-6.82,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C19H13Cl2N5O/c1-26-17-11(9-23-19(25-17)24-12-4-3-7-22-10-12)8-13(18(26)27)16-14(20)5-2-6-15(16)21/h2-10H,1H3,(H,23,24,25)	SJHLMHPRVRNIFW-UHFFFAOYSA-N	3073	6-(2,6-dichlorophenyl)-8-methyl-2-(pyridin-3-ylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::6-(2,6-Dichlorophenyl)-8-methyl-2-(pyridin-3-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 40	Epidermal growth factor receptor	Homo sapiens		 510							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3073	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3073&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327887	8032820							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4086	COc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cn1 |(-7.06,-7.68,;-8.15,-6.59,;-8.15,-5.05,;-9.48,-4.28,;-9.48,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-6.82,-2.74,;-6.82,-4.28,)|	InChI=1S/C20H15Cl2N5O2/c1-27-18-11(8-13(19(27)28)17-14(21)4-3-5-15(17)22)9-24-20(26-18)25-12-6-7-16(29-2)23-10-12/h3-10H,1-2H3,(H,24,25,26)	NBPINIBREWXSRV-UHFFFAOYSA-N	3074	6-(2,6-dichlorophenyl)-2-[(6-methoxypyridin-3-yl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 41	Epidermal growth factor receptor	Homo sapiens		 1300							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3074	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3074&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327888	8032821							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4087	Cn1c2nc(Nc3ccncc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.82,-2.74,;-6.82,-4.28,;-8.15,-5.05,;-9.48,-4.28,;-9.48,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C19H13Cl2N5O/c1-26-17-11(10-23-19(25-17)24-12-5-7-22-8-6-12)9-13(18(26)27)16-14(20)3-2-4-15(16)21/h2-10H,1H3,(H,22,23,24,25)	YOKSFKATMBKCHB-UHFFFAOYSA-N	3075	6-(2,6-dichlorophenyl)-8-methyl-2-(pyridin-4-ylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42	Epidermal growth factor receptor	Homo sapiens		 910							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3075	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3075&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327889	8032822							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4100	CCn1c2nc(Nc3ccncc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-1.73,-3.06,;-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.82,-2.74,;-6.82,-4.28,;-8.15,-5.05,;-9.48,-4.28,;-9.48,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H15Cl2N5O/c1-2-27-18-12(11-24-20(26-18)25-13-6-8-23-9-7-13)10-14(19(27)28)17-15(21)4-3-5-16(17)22/h3-11H,2H2,1H3,(H,23,24,25,26)	DAZNPHVDUSTLGK-UHFFFAOYSA-N	3076	6-(2,6-dichlorophenyl)-8-ethyl-2-(pyridin-4-ylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 43	Epidermal growth factor receptor	Homo sapiens		 490							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3076	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3076&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327890	8032823							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4101	Cn1c2nc(Nc3ccc(Cl)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.82,-2.74,;-6.82,-4.28,;-8.15,-5.05,;-8.15,-6.59,;-9.48,-4.28,;-9.48,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H13Cl3N4O/c1-27-18-11(9-14(19(27)28)17-15(22)3-2-4-16(17)23)10-24-20(26-18)25-13-7-5-12(21)6-8-13/h2-10H,1H3,(H,24,25,26)	NHNZOSYAEBEEDW-UHFFFAOYSA-N	3077	2-[(4-chlorophenyl)amino]-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 44	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3077	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3077&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327891	8032824							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4102	Cn1c2nc(Nc3cccc(Br)c3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-9.48,-2.74,;-9.48,-4.28,;-8.15,-5.05,;-6.82,-4.28,;-5.48,-5.05,;-6.82,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H13BrCl2N4O/c1-27-18-11(8-14(19(27)28)17-15(22)6-3-7-16(17)23)10-24-20(26-18)25-13-5-2-4-12(21)9-13/h2-10H,1H3,(H,24,25,26)	LXANAWKXDMMAQX-UHFFFAOYSA-N	3078	2-[(3-bromophenyl)amino]-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 45	Epidermal growth factor receptor	Homo sapiens		 670							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3078	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3078&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327892	8032825							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4103	Cc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 |(-8.15,-6.59,;-8.15,-5.05,;-9.48,-4.28,;-9.48,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-6.82,-2.74,;-6.82,-4.28,)|	InChI=1S/C21H16Cl2N4O/c1-12-6-8-14(9-7-12)25-21-24-11-13-10-15(20(28)27(2)19(13)26-21)18-16(22)4-3-5-17(18)23/h3-11H,1-2H3,(H,24,25,26)	ZLNBJDSAGVBJSP-UHFFFAOYSA-N	3079	6-(2,6-dichlorophenyl)-8-methyl-2-[(4-methylphenyl)amino]-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 46	Epidermal growth factor receptor	Homo sapiens		 480							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3079	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3079&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327893	8032826							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4119	COc1ccccc1Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-12.15,-2.74,;-10.82,-1.97,;-9.48,-2.74,;-9.48,-4.28,;-8.15,-5.05,;-6.82,-4.28,;-6.82,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,)|	InChI=1S/C21H16Cl2N4O2/c1-27-19-12(10-13(20(27)28)18-14(22)6-5-7-15(18)23)11-24-21(26-19)25-16-8-3-4-9-17(16)29-2/h3-11H,1-2H3,(H,24,25,26)	FCUQJIQLHXSQHY-UHFFFAOYSA-N	3080	6-(2,6-dichlorophenyl)-2-[(2-methoxyphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 47	Epidermal growth factor receptor	Homo sapiens		 660							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3080	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3080&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327894	8032827							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4120	COc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 |(-12.15,-4.28,;-10.82,-5.05,;-9.48,-4.28,;-8.15,-5.05,;-6.82,-4.28,;-6.82,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-9.48,-2.74,)|	InChI=1S/C21H16Cl2N4O2/c1-27-19-12(9-15(20(27)28)18-16(22)7-4-8-17(18)23)11-24-21(26-19)25-13-5-3-6-14(10-13)29-2/h3-11H,1-2H3,(H,24,25,26)	IDCFPJHKTOPZHU-UHFFFAOYSA-N	3081	6-(2,6-dichlorophenyl)-2-[(3-methoxyphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 48	Epidermal growth factor receptor	Homo sapiens		 30							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3081	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3081&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327895	8032828							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4121	COc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 |(-7.06,-7.68,;-8.15,-6.59,;-8.15,-5.05,;-6.82,-4.28,;-6.82,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-9.48,-2.74,;-9.48,-4.28,)|	InChI=1S/C21H16Cl2N4O2/c1-27-19-12(10-15(20(27)28)18-16(22)4-3-5-17(18)23)11-24-21(26-19)25-13-6-8-14(29-2)9-7-13/h3-11H,1-2H3,(H,24,25,26)	ZDVPZVBAWYNOOH-UHFFFAOYSA-N	3082	6-(2,6-Dichlorophenyl)-2-(4-methoxyphenylamino)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one::6-(2,6-dichlorophenyl)-2-[(4-methoxyphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 49	Epidermal growth factor receptor	Homo sapiens		 220							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3082	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3082&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327896	8032829							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4122	Cn1c2nc(Nc3cccc(O)c3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.82,-2.74,;-6.82,-4.28,;-8.15,-5.05,;-9.48,-4.28,;-10.82,-5.05,;-9.48,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H14Cl2N4O2/c1-26-18-11(8-14(19(26)28)17-15(21)6-3-7-16(17)22)10-23-20(25-18)24-12-4-2-5-13(27)9-12/h2-10,27H,1H3,(H,23,24,25)	YLOVBNCIDYKIDW-UHFFFAOYSA-N	3083	PD 166285 analog::6-(2,6-dichlorophenyl)-2-[(3-hydroxyphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 50	Epidermal growth factor receptor	Homo sapiens		 150							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3083	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3083&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327897	8032830							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4123	Cn1c2nc(Nc3ccc(O)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.82,-2.74,;-6.82,-4.28,;-8.15,-5.05,;-8.15,-6.59,;-9.48,-4.28,;-9.48,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C20H14Cl2N4O2/c1-26-18-11(9-14(19(26)28)17-15(21)3-2-4-16(17)22)10-23-20(25-18)24-12-5-7-13(27)8-6-12/h2-10,27H,1H3,(H,23,24,25)	XLLINEQPLUTYIF-UHFFFAOYSA-N	3084	6-(2,6-dichlorophenyl)-2-[(4-hydroxyphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::6-(2,6-dichlorophenyl)-2-[(4-hydroxyphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 51	Epidermal growth factor receptor	Homo sapiens									Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3084	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3084&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327898	8032831							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4139	CN1c2c(cnc(n2)Nc3cccc(c3)CO)C=C(C1=O)c4c(cccc4Cl)Cl	InChI=1S/C21H16Cl2N4O2/c1-27-19-13(9-15(20(27)29)18-16(22)6-3-7-17(18)23)10-24-21(26-19)25-14-5-2-4-12(8-14)11-28/h2-10,28H,11H2,1H3,(H,24,25,26)	ZIQFYVPVJZEOFS-UHFFFAOYSA-N	3085	6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::PD166326	Epidermal growth factor receptor	Homo sapiens		 90							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3085	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	P16	2FO0,2G2H,1OPK,1OPL	447700	8032832			DB08339				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4140	COc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1C |(-7.06,-7.68,;-8.15,-6.59,;-8.15,-5.05,;-6.82,-4.28,;-6.82,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-9.48,-2.74,;-9.48,-4.28,;-10.82,-5.05,)|	InChI=1S/C22H18Cl2N4O2/c1-12-9-14(7-8-18(12)30-3)26-22-25-11-13-10-15(21(29)28(2)20(13)27-22)19-16(23)5-4-6-17(19)24/h4-11H,1-3H3,(H,25,26,27)	PBDZUUYDHCFPJM-UHFFFAOYSA-N	3086	PD 166285 analog::6-(2,6-dichlorophenyl)-2-[(4-methoxy-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 53	Epidermal growth factor receptor	Homo sapiens		 250							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3086&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327899	8032833							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4141	COc1cc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc(OC)c1 |(-12.15,-4.28,;-10.82,-5.05,;-9.48,-4.28,;-9.48,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-6.82,-2.74,;-6.82,-4.28,;-5.48,-5.05,;-4.15,-4.28,;-8.15,-5.05,)|	InChI=1S/C22H18Cl2N4O3/c1-28-20-12(7-16(21(28)29)19-17(23)5-4-6-18(19)24)11-25-22(27-20)26-13-8-14(30-2)10-15(9-13)31-3/h4-11H,1-3H3,(H,25,26,27)	RYCIKEDAOOTILW-UHFFFAOYSA-N	3087	PD 166285 analog::6-(2,6-dichlorophenyl)-2-[(3,5-dimethoxyphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 54	Epidermal growth factor receptor	Homo sapiens		 330							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3087	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3087&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327900	8032834							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4142	CCOC(=O)c1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 |(-14.82,-4.28,;-13.49,-5.05,;-12.15,-4.28,;-10.82,-5.05,;-10.82,-6.59,;-9.48,-4.28,;-8.15,-5.05,;-6.82,-4.28,;-6.82,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-9.48,-2.74,)|	InChI=1S/C23H18Cl2N4O3/c1-3-32-22(31)13-6-4-7-15(10-13)27-23-26-12-14-11-16(21(30)29(2)20(14)28-23)19-17(24)8-5-9-18(19)25/h4-12H,3H2,1-2H3,(H,26,27,28)	OHRKRHOJNKVMAQ-UHFFFAOYSA-N	3088	ethyl 3-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl]amino}benzoate::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 55	Epidermal growth factor receptor	Homo sapiens									Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3088	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3088&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327901	8032835							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4143	CCOC(=O)c1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 |(-4.15,-7.36,;-5.48,-6.59,;-6.82,-7.36,;-8.15,-6.59,;-9.48,-7.36,;-8.15,-5.05,;-6.82,-4.28,;-6.82,-2.74,;-8.15,-1.97,;-8.15,-.43,;-6.82,.34,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,;-2.82,-.43,;-2.82,-1.97,;-4.15,.34,;-5.48,-.43,;-9.48,-2.74,;-9.48,-4.28,)|	InChI=1S/C23H18Cl2N4O3/c1-3-32-22(31)13-7-9-15(10-8-13)27-23-26-12-14-11-16(21(30)29(2)20(14)28-23)19-17(24)5-4-6-18(19)25/h4-12H,3H2,1-2H3,(H,26,27,28)	NYRCHGFYXOCTEO-UHFFFAOYSA-N	3089	ethyl 4-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl]amino}benzoate::PD 166285 analog::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 56	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3089	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3089&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327902	8032836							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4165	CCN(CC)CCOc1ccc(cc1)Nc2ncc3c(n2)N(C(=O)C(=C3)c4c(cccc4Cl)Cl)C	InChI=1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2,1-3H3,(H,29,30,31)	IFPPYSWJNWHOLQ-UHFFFAOYSA-N	3096	6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::6-(2,6-Dichlorophenyl)-2-[4-(2-diethylaminoethoxy)phenylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one, Dihydrochloride::CHEMBL49120::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv.::PD166285::D3RKN_84	Epidermal growth factor receptor	Homo sapiens		 44							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3096	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	96M	5VC5	5311382	8032843		CHEMBL49120					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4193	Cn1c2nc(Nc3cccc(c3)C(O)=O)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-6.82,-2.74,;-6.82,-4.28,;-8.15,-5.05,;-9.48,-4.28,;-9.48,-2.74,;-10.82,-5.05,;-12.15,-4.28,;-10.82,-6.59,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C21H14Cl2N4O3/c1-27-18-12(9-14(19(27)28)17-15(22)6-3-7-16(17)23)10-24-21(26-18)25-13-5-2-4-11(8-13)20(29)30/h2-10H,1H3,(H,29,30)(H,24,25,26)	RBURTLAMOSHNGX-UHFFFAOYSA-N	3103	PD 166285 analog::3-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl]amino}benzoic acid::3-[6-(2,6-Dichlorophenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino]benzoic Acid::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 70	Epidermal growth factor receptor	Homo sapiens		 190							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3103	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3103&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327916	8032850							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4194	Cn1c2nc(Nc3ccc(CC(O)=O)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-9.48,-2.74,;-9.48,-4.28,;-8.15,-5.05,;-8.15,-6.59,;-7.38,-7.93,;-5.84,-7.93,;-8.15,-9.26,;-6.82,-4.28,;-6.82,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C22H16Cl2N4O3/c1-28-20-13(10-15(21(28)31)19-16(23)3-2-4-17(19)24)11-25-22(27-20)26-14-7-5-12(6-8-14)9-18(29)30/h2-8,10-11H,9H2,1H3,(H,29,30)(H,25,26,27)	AMKNQROTNAOJQE-UHFFFAOYSA-N	3104	2-(4-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl]amino}phenyl)acetic acid::PD 166285 analog::CHEMBL50647::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 71	Epidermal growth factor receptor	Homo sapiens		 220							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3104	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3104&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327917	8032851		CHEMBL50647			C03768		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4195	Cn1c2nc(Nc3ccc(CCCC(O)=O)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-2.82,-1.97,;-2.82,-.43,;-4.15,.34,;-5.48,-.43,;-6.82,.34,;-8.15,-.43,;-8.15,-1.97,;-9.48,-2.74,;-9.48,-4.28,;-8.15,-5.05,;-8.15,-6.59,;-7.38,-7.93,;-8.15,-9.26,;-7.06,-10.35,;-5.57,-10.75,;-7.83,-11.68,;-6.82,-4.28,;-6.82,-2.74,;-6.82,1.88,;-5.48,2.65,;-4.15,1.88,;-2.82,2.65,;-1.48,1.88,;-.15,2.65,;-.15,4.19,;-1.48,4.96,;1.18,4.96,;2.52,4.19,;2.52,2.65,;1.18,1.88,;1.18,.34,;-1.48,.34,;-.15,-.43,)|	InChI=1S/C24H20Cl2N4O3/c1-30-22-15(12-17(23(30)33)21-18(25)5-3-6-19(21)26)13-27-24(29-22)28-16-10-8-14(9-11-16)4-2-7-20(31)32/h3,5-6,8-13H,2,4,7H2,1H3,(H,31,32)(H,27,28,29)	CBIJGNHFFWAGLZ-UHFFFAOYSA-N	3105	4-(4-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl]amino}phenyl)butanoic acid::PD 166285 analog::CHEMBL113070::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72	Epidermal growth factor receptor	Homo sapiens		 80							Curated from the literature by BindingDB	10.1021/jm9802259	10.7270/Q27P8WK3	9703473	aid1795457		Klutchko, SR; Hamby, JM; Boschelli, DH; Wu, Z; Kraker, AJ; Amar, AM; Hartl, BG; Shen, C; Klohs, WD; Steinkampf, RW; Driscoll, DL; Nelson, JM; Elliott, WL; Roberts, BJ; Stoner, CL; Vincent, PW; Dykes, DJ; Panek, RL; Lu, GH; Major, TC; Dahring, TK; Hallak, H; Bradford, LA; Showalter, HD; Doherty, AM	8/13/1998	1/18/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3105&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5327918	8032852		CHEMBL113070					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4841	c1ccc(cc1)CCNc2c3ccccc3ncn2	InChI=1S/C16H15N3/c1-2-6-13(7-3-1)10-11-17-16-14-8-4-5-9-15(14)18-12-19-16/h1-9,12H,10-11H2,(H,17,18,19)	YKOSADJQCBRMRR-UHFFFAOYSA-N	3255	N-(2-phenylethyl)quinazolin-4-amine::4-Anilino quinazoline deriv. 6	Epidermal growth factor receptor	Homo sapiens		 4100					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3255	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3255&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0SW	4F7S	198909	8032997							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4842	C(Nc1ncnc2ccccc12)c1ccccc1	InChI=1S/C15H13N3/c1-2-6-12(7-3-1)10-16-15-13-8-4-5-9-14(13)17-11-18-15/h1-9,11H,10H2,(H,16,17,18)	FVWANTDQRFSCAL-UHFFFAOYSA-N	3256	N-benzylquinazolin-4-amine::benzyl(quinazolin-4-yl)amine;hydrochloride::cid_616573::4-(Benzylamino)quinazoline deriv. 7	Epidermal growth factor receptor	Homo sapiens		 320					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3256	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3256&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			616573	8032998							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4843	c1ccc2c(c1)c(ncn2)NCc3ccc(cc3)Cl	InChI=1S/C15H12ClN3/c16-12-7-5-11(6-8-12)9-17-15-13-3-1-2-4-14(13)18-10-19-15/h1-8,10H,9H2,(H,17,18,19)	BTRLSAYDVSPYCS-UHFFFAOYSA-N	3257	N-[(4-chlorophenyl)methyl]quinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 8	Epidermal growth factor receptor	Homo sapiens		 7000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3257	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3257&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	MFE	6T41	5328014	8032999							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4844	COc1ccc(CNc2ncnc3ccccc23)cc1	InChI=1S/C16H15N3O/c1-20-13-8-6-12(7-9-13)10-17-16-14-4-2-3-5-15(14)18-11-19-16/h2-9,11H,10H2,1H3,(H,17,18,19)	MCZPCSYKZMFAHI-UHFFFAOYSA-N	3258	N-[(4-methoxyphenyl)methyl]quinazolin-4-amine::cid_5328015::4-(Benzylamino)quinazoline deriv. 9	Epidermal growth factor receptor	Homo sapiens		 10000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3258	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3258&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328015	8033000							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4845	N(c1ccccc1)c1ncnc2ccccc12	InChI=1S/C14H11N3/c1-2-6-11(7-3-1)17-14-12-8-4-5-9-13(12)15-10-16-14/h1-10H,(H,15,16,17)	MTSNDBYBIZSILH-UHFFFAOYSA-N	3259	N-phenylquinazolin-4-amine::CHEMBL289959::4-Anilino quinazoline deriv. 10	Epidermal growth factor receptor	Homo sapiens		 344					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3259	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3259&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			324081	8033001		CHEMBL289959					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4846	CN(c1ccccc1)c1ncnc2ccccc12	InChI=1S/C15H13N3/c1-18(12-7-3-2-4-8-12)15-13-9-5-6-10-14(13)16-11-17-15/h2-11H,1H3	VCLXUEIYTZFLMO-UHFFFAOYSA-N	3260	N-methyl-N-phenylquinazolin-4-amine::4-Anilino quinazoline deriv. 11	Epidermal growth factor receptor	Homo sapiens		 100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3260	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3260&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328016	8033002							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4847	COc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C15H13N3O/c1-19-12-6-4-5-11(9-12)18-15-13-7-2-3-8-14(13)16-10-17-15/h2-10H,1H3,(H,16,17,18)	LCYPRFCDTJTQPG-UHFFFAOYSA-N	3261	N-(3-methoxyphenyl)quinazolin-4-amine::4-Anilino quinazoline deriv. 12	Epidermal growth factor receptor	Homo sapiens		 842					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3261	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3261&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			712193	8033003							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4848	Cc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C15H13N3/c1-11-5-4-6-12(9-11)18-15-13-7-2-3-8-14(13)16-10-17-15/h2-10H,1H3,(H,16,17,18)	AHFDWKXLJCGQHE-UHFFFAOYSA-N	3262	N-(3-methylphenyl)quinazolin-4-amine::4-Anilino quinazoline deriv. 13	Epidermal growth factor receptor	Homo sapiens		 910					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3262	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3262&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			659954	8033004							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4849	Clc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10ClN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	ZKKVUIPXPPDIRD-UHFFFAOYSA-N	3263	CHEMBL329672::N-(3-chlorophenyl)quinazolin-4-amine::CHEMBL555321::4-Anilino quinazoline deriv. 14	Epidermal growth factor receptor	Homo sapiens		 23					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3263	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3263&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			128872	8033005		CHEMBL555321CHEMBL329672					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4850	Brc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10BrN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	SUTRLYZWRGPLSJ-UHFFFAOYSA-N	3264	CHEMBL290096::N-(3-bromophenyl)quinazolin-4-amine::4-Anilino quinazoline deriv. 15	Epidermal growth factor receptor	Homo sapiens		 27					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3264	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3264&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			735125	8033006		CHEMBL290096					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4851	Ic1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10IN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	LCUWAJDEGKZDMI-UHFFFAOYSA-N	3265	CHEMBL92825::N-(3-iodophenyl)quinazolin-4-amine::4-Anilino quinazoline deriv. 16	Epidermal growth factor receptor	Homo sapiens		 80					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3265	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3265&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			735126	8033007		CHEMBL92825					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4852	FC(F)(F)c1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C15H10F3N3/c16-15(17,18)10-4-3-5-11(8-10)21-14-12-6-1-2-7-13(12)19-9-20-14/h1-9H,(H,19,20,21)	VCOMYMMMFREKQC-UHFFFAOYSA-N	3266	CHEMBL92824::N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine::4-Anilino quinazoline deriv. 17	Epidermal growth factor receptor	Homo sapiens		 577					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3266	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3266&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			651672	8033008		CHEMBL92824					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4853	N(c1cccnc1)c1ncnc2ccccc12	InChI=1S/C13H10N4/c1-2-6-12-11(5-1)13(16-9-15-12)17-10-4-3-7-14-8-10/h1-9H,(H,15,16,17)	KOQRKDRUVGQCBR-UHFFFAOYSA-N	3267	N-(pyridin-3-yl)quinazolin-4-amine::4-Anilino quinazoline deriv. 18	Epidermal growth factor receptor	Homo sapiens		>1000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3267	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3267&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328017	8033009							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4854	Brc1cccc(Oc2ncnc3ccccc23)c1	InChI=1S/C14H9BrN2O/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H	GHYKYLGHIXGESB-UHFFFAOYSA-N	3268	4-(3-bromophenoxy)quinazoline::4-Anilino quinazoline deriv. 19	Epidermal growth factor receptor	Homo sapiens		 756					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3268	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3268&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328018	8033010							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4855	Brc1cccc(Nc2ccnc3ccccc23)c1	InChI=1S/C15H11BrN2/c16-11-4-3-5-12(10-11)18-15-8-9-17-14-7-2-1-6-13(14)15/h1-10H,(H,17,18)	HANOGSNEKFKCMV-UHFFFAOYSA-N	3269	N-(3-bromophenyl)quinolin-4-amine::quinoline deriv. 20	Epidermal growth factor receptor	Homo sapiens		 5500					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3269	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3269&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328019	8033011							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4856	Brc1cccc(Nc2nccc3ccccc23)c1	InChI=1S/C15H11BrN2/c16-12-5-3-6-13(10-12)18-15-14-7-2-1-4-11(14)8-9-17-15/h1-10H,(H,17,18)	XLUUAOKSTRHPIZ-UHFFFAOYSA-N	3270	N-(3-bromophenyl)isoquinolin-1-amine::isoquinoline deriv. 21	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3270	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3270&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4321095	8033012							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4857	Brc1cccc(Nc2cnnc3ccccc23)c1	InChI=1S/C14H10BrN3/c15-10-4-3-5-11(8-10)17-14-9-16-18-13-7-2-1-6-12(13)14/h1-9H,(H,17,18)	WVNAAWCVKNMCCQ-UHFFFAOYSA-N	3271	N-(3-bromophenyl)cinnolin-4-amine::cinnoline deriv. 22	Epidermal growth factor receptor	Homo sapiens		>10000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3271	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3271&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328020	8033013							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4858	Brc1cccc(Nc2nncc3ccccc23)c1	InChI=1S/C14H10BrN3/c15-11-5-3-6-12(8-11)17-14-13-7-2-1-4-10(13)9-16-18-14/h1-9H,(H,17,18)	GTYRWVZYZNJYJM-UHFFFAOYSA-N	3272	N-(3-bromophenyl)phthalazin-1-amine::phthalazine deriv. 23	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3272	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3272&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328021	8033014							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4859	Brc1cccc(Nc2cnc3ccccc3n2)c1	InChI=1S/C14H10BrN3/c15-10-4-3-5-11(8-10)17-14-9-16-12-6-1-2-7-13(12)18-14/h1-9H,(H,17,18)	LNWNETBRARCZRM-UHFFFAOYSA-N	3273	N-(3-bromophenyl)quinoxalin-2-amine::quinoxaline deriv. 24	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3273	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3273&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328022	8033015							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4860	Brc1cccc(Nc2nnnc3ccccc23)c1	InChI=1S/C13H9BrN4/c14-9-4-3-5-10(8-9)15-13-11-6-1-2-7-12(11)16-18-17-13/h1-8H,(H,15,16,17)	JHEUTLNGYTXKOM-UHFFFAOYSA-N	3274	N-(3-bromophenyl)-1,2,3-benzotriazin-4-amine::4-[(3-Bromophenyl)amino]-1,2,3-benzotriazine::Benzotriazine deriv. 25	Epidermal growth factor receptor	Homo sapiens		>1000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3274	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3274&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328023	8033016							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4861	[O-][N+](=O)c1cccc2ncnc(NCc3ccccc3)c12	InChI=1S/C15H12N4O2/c20-19(21)13-8-4-7-12-14(13)15(18-10-17-12)16-9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H,16,17,18)	VYDBASPMDRHHCU-UHFFFAOYSA-N	3275	N-benzyl-5-nitroquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 26	Epidermal growth factor receptor	Homo sapiens		 8000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3275	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3275&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328024	8033017							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4862	Nc1cccc2ncnc(NCc3ccccc3)c12	InChI=1S/C15H14N4/c16-12-7-4-8-13-14(12)15(19-10-18-13)17-9-11-5-2-1-3-6-11/h1-8,10H,9,16H2,(H,17,18,19)	MBUYMCKMFDNNPH-UHFFFAOYSA-N	3276	4-N-benzylquinazoline-4,5-diamine::4-(Benzylamino)quinazoline deriv. 27	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3276	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3276&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328025	8033018							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4863	COc1cccc2ncnc(NCc3ccccc3)c12	InChI=1S/C16H15N3O/c1-20-14-9-5-8-13-15(14)16(19-11-18-13)17-10-12-6-3-2-4-7-12/h2-9,11H,10H2,1H3,(H,17,18,19)	WRYWVLLIKZNFQK-UHFFFAOYSA-N	3277	N-benzyl-5-methoxyquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 28	Epidermal growth factor receptor	Homo sapiens		 4900							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3277	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3277&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328026	8033019							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4864	[O-][N+](=O)c1ccc2ncnc(NCc3ccccc3)c2c1	InChI=1S/C15H12N4O2/c20-19(21)12-6-7-14-13(8-12)15(18-10-17-14)16-9-11-4-2-1-3-5-11/h1-8,10H,9H2,(H,16,17,18)	MUFPYUMPKFPPPJ-UHFFFAOYSA-N	3278	N-benzyl-6-nitroquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 29	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3278	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3278&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328027	8033020							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4865	Nc1ccc2ncnc(NCc3ccccc3)c2c1	InChI=1S/C15H14N4/c16-12-6-7-14-13(8-12)15(19-10-18-14)17-9-11-4-2-1-3-5-11/h1-8,10H,9,16H2,(H,17,18,19)	KLOMJHRLJJRYDX-UHFFFAOYSA-N	3279	CHEMBL332096::4-N-benzylquinazoline-4,6-diamine::4-(Benzylamino)quinazoline deriv. 30	Epidermal growth factor receptor	Homo sapiens		 1400							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3279	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3279&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328028	8033021		CHEMBL332096					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4866	COc1ccc2ncnc(NCc3ccccc3)c2c1	InChI=1S/C16H15N3O/c1-20-13-7-8-15-14(9-13)16(19-11-18-15)17-10-12-5-3-2-4-6-12/h2-9,11H,10H2,1H3,(H,17,18,19)	FNDTUROJPCNKSJ-UHFFFAOYSA-N	3280	N-benzyl-6-methoxyquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 31	Epidermal growth factor receptor	Homo sapiens		 200							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3280	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3280&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328029	8033022							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4867	[O-][N+](=O)c1ccc2c(NCc3ccccc3)ncnc2c1	InChI=1S/C15H12N4O2/c20-19(21)12-6-7-13-14(8-12)17-10-18-15(13)16-9-11-4-2-1-3-5-11/h1-8,10H,9H2,(H,16,17,18)	LFJDGEHGHHXGBE-UHFFFAOYSA-N	3281	N-benzyl-7-nitroquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 32	Epidermal growth factor receptor	Homo sapiens		 5900							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3281	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3281&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328030	8033023							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4868	Nc1ccc2c(NCc3ccccc3)ncnc2c1	InChI=1S/C15H14N4/c16-12-6-7-13-14(8-12)18-10-19-15(13)17-9-11-4-2-1-3-5-11/h1-8,10H,9,16H2,(H,17,18,19)	YALFOGLJKIYCIY-UHFFFAOYSA-N	3282	4-N-benzylquinazoline-4,7-diamine::4-(Benzylamino)quinazoline deriv. 33	Epidermal growth factor receptor	Homo sapiens		>1000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3282	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3282&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328031	8033024							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4869	COc1ccc2c(NCc3ccccc3)ncnc2c1	InChI=1S/C16H15N3O/c1-20-13-7-8-14-15(9-13)18-11-19-16(14)17-10-12-5-3-2-4-6-12/h2-9,11H,10H2,1H3,(H,17,18,19)	WVKPEHVWDHASND-UHFFFAOYSA-N	3283	N-benzyl-7-methoxyquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 34	Epidermal growth factor receptor	Homo sapiens		 58							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3283	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3283&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328032	8033025							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4870	[O-][N+](=O)c1cccc2c(NCc3ccccc3)ncnc12	InChI=1S/C15H12N4O2/c20-19(21)13-8-4-7-12-14(13)17-10-18-15(12)16-9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H,16,17,18)	YPNFBKKXWWCFEI-UHFFFAOYSA-N	3284	N-benzyl-8-nitroquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 35	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3284	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3284&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328033	8033026							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4871	Nc1cccc2c(NCc3ccccc3)ncnc12	InChI=1S/C15H14N4/c16-13-8-4-7-12-14(13)18-10-19-15(12)17-9-11-5-2-1-3-6-11/h1-8,10H,9,16H2,(H,17,18,19)	MATCDJOSGXADJJ-UHFFFAOYSA-N	3285	4-N-benzylquinazoline-4,8-diamine::4-(Benzylamino)quinazoline deriv. 36	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3285	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3285&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328034	8033027							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4872	COc1cccc2c(NCc3ccccc3)ncnc12	InChI=1S/C16H15N3O/c1-20-14-9-5-8-13-15(14)18-11-19-16(13)17-10-12-6-3-2-4-7-12/h2-9,11H,10H2,1H3,(H,17,18,19)	ACWOCKBRFHRZLC-UHFFFAOYSA-N	3286	N-benzyl-8-methoxyquinazolin-4-amine::4-(Benzylamino)quinazoline deriv. 37	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3286	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3286&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328035	8033028							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4873	COc1cc2c(NCc3ccccc3)ncnc2cc1O	InChI=1S/C16H15N3O2/c1-21-15-7-12-13(8-14(15)20)18-10-19-16(12)17-9-11-5-3-2-4-6-11/h2-8,10,20H,9H2,1H3,(H,17,18,19)	YKDOURWNBDLSNO-UHFFFAOYSA-N	3287	4-(benzylamino)-6-methoxyquinazolin-7-ol::7-Hydroxy-6-methoxy4[ (phenylmethy1)aminolquinazoline::4-(Benzylamino)quinazoline deriv. 38	Epidermal growth factor receptor	Homo sapiens		 588							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3287	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3287&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328036	8033029							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4874	COc1cc2ncnc(NCc3ccccc3)c2cc1O	InChI=1S/C16H15N3O2/c1-21-15-8-13-12(7-14(15)20)16(19-10-18-13)17-9-11-5-3-2-4-6-11/h2-8,10,20H,9H2,1H3,(H,17,18,19)	ARGNVJPDKVQMDV-UHFFFAOYSA-N	3288	4-(benzylamino)-7-methoxyquinazolin-6-ol::4-(Benzylamino)quinazoline deriv. 39	Epidermal growth factor receptor	Homo sapiens		 56							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3288	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3288&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328037	8033030							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4875	COc1cc2ncnc(NCc3ccccc3)c2cc1OC	InChI=1S/C17H17N3O2/c1-21-15-8-13-14(9-16(15)22-2)19-11-20-17(13)18-10-12-6-4-3-5-7-12/h3-9,11H,10H2,1-2H3,(H,18,19,20)	FVWVAEZYXLGVIV-UHFFFAOYSA-N	3289	N-benzyl-6,7-dimethoxyquinazolin-4-amine::CHEMBL545541::4-(Benzylamino)quinazoline deriv. 40	Epidermal growth factor receptor	Homo sapiens		 10							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3289	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3289&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1474877	8033031		CHEMBL545541					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4876	[O-][N+](=O)c1cccc2ncnc(Nc3cccc(Br)c3)c12	InChI=1S/C14H9BrN4O2/c15-9-3-1-4-10(7-9)18-14-13-11(16-8-17-14)5-2-6-12(13)19(20)21/h1-8H,(H,16,17,18)	CFLDNHCFXUEPKN-UHFFFAOYSA-N	3290	N-(3-bromophenyl)-5-nitroquinazolin-4-amine::4-Anilinoquinazoline deriv. 41	Epidermal growth factor receptor	Homo sapiens		 355							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3290	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3290&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328038	8033032							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4877	Nc1cccc2ncnc(Nc3cccc(Br)c3)c12	InChI=1S/C14H11BrN4/c15-9-3-1-4-10(7-9)19-14-13-11(16)5-2-6-12(13)17-8-18-14/h1-8H,16H2,(H,17,18,19)	VFDHVXMKHJATKX-UHFFFAOYSA-N	3291	4-N-(3-bromophenyl)quinazoline-4,5-diamine::4-Anilinoquinazoline deriv. 42	Epidermal growth factor receptor	Homo sapiens		 439							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3291	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3291&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328039	8033033							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4878	COc1cccc2ncnc(Nc3cccc(Br)c3)c12	InChI=1S/C15H12BrN3O/c1-20-13-7-3-6-12-14(13)15(18-9-17-12)19-11-5-2-4-10(16)8-11/h2-9H,1H3,(H,17,18,19)	HMMROPZSAUEXBD-UHFFFAOYSA-N	3292	N-(3-bromophenyl)-5-methoxyquinazolin-4-amine::4-Anilinoquinazoline deriv. 43	Epidermal growth factor receptor	Homo sapiens		 139							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3292	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3292&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328040	8033034							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4879	[O-][N+](=O)c1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C14H9BrN4O2/c15-9-2-1-3-10(6-9)18-14-12-7-11(19(20)21)4-5-13(12)16-8-17-14/h1-8H,(H,16,17,18)	MAVKGSSRIBVAGI-UHFFFAOYSA-N	3293	CHEMBL329161::N-(3-bromophenyl)-6-nitroquinazolin-4-amine::4-Anilinoquinazoline deriv. 44	Epidermal growth factor receptor	Homo sapiens		 897							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3293	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3293&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328041	8033035		CHEMBL329161					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4880	Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C14H11BrN4/c15-9-2-1-3-11(6-9)19-14-12-7-10(16)4-5-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	IZQHULBHKPGOAP-UHFFFAOYSA-N	3294	CHEMBL52765::4-N-(3-bromophenyl)quinazoline-4,6-diamine::Anilinoquinazoline, 4b::4-Anilinoquinazoline deriv. 45	Epidermal growth factor receptor	Homo sapiens		 0.79							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328042	8033036		CHEMBL52765					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4881	COc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C15H12BrN3O/c1-20-12-5-6-14-13(8-12)15(18-9-17-14)19-11-4-2-3-10(16)7-11/h2-9H,1H3,(H,17,18,19)	LDTMDWOXHYGMAM-UHFFFAOYSA-N	3295	CHEMBL52197::N-(3-bromophenyl)-6-methoxyquinazolin-4-amine::4-Anilinoquinazoline deriv. 46	Epidermal growth factor receptor	Homo sapiens		 348							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3295	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3295&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328043	8033037		CHEMBL52197					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4882	[O-][N+](=O)c1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C14H9BrN4O2/c15-9-2-1-3-10(6-9)18-14-12-5-4-11(19(20)21)7-13(12)16-8-17-14/h1-8H,(H,16,17,18)	RZBBKHCMKJSCKV-UHFFFAOYSA-N	3296	CHEMBL94275::4-[(3-Bromophenyl)amino]-7-nitroquinazoline::N-(3-bromophenyl)-7-nitroquinazolin-4-amine::4-Anilinoquinazoline deriv. 47	Epidermal growth factor receptor	Homo sapiens		 1000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3296	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3296&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328044	8033038		CHEMBL94275					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4883	Nc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C14H11BrN4/c15-9-2-1-3-11(6-9)19-14-12-5-4-10(16)7-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	GHVBIROTJQDRQB-UHFFFAOYSA-N	3297	4-N-(3-bromophenyl)quinazoline-4,7-diamine::7-Amino-4-[(3-bromophenyl)aminolquinazoline::CHEMBL420624::4-Anilinoquinazoline deriv. 48	Epidermal growth factor receptor	Homo sapiens		 0.1							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3297	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3297&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328045	8033039		CHEMBL420624					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4884	COc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C15H12BrN3O/c1-20-12-5-6-13-14(8-12)17-9-18-15(13)19-11-4-2-3-10(16)7-11/h2-9H,1H3,(H,17,18,19)	CDWGVMQLDOQALI-UHFFFAOYSA-N	3298	N-(3-bromophenyl)-7-methoxyquinazolin-4-amine::CHEMBL93181::4-Anilinoquinazoline deriv. 49	Epidermal growth factor receptor	Homo sapiens		 10							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3298	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3298&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328046	8033040		CHEMBL93181					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4885	[O-][N+](=O)c1cccc2c(Nc3cccc(Br)c3)ncnc12	InChI=1S/C14H9BrN4O2/c15-9-3-1-4-10(7-9)18-14-11-5-2-6-12(19(20)21)13(11)16-8-17-14/h1-8H,(H,16,17,18)	QJBJVUJYJKBCJC-UHFFFAOYSA-N	3299	N-(3-bromophenyl)-8-nitroquinazolin-4-amine::4-Anilinoquinazoline deriv. 50	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3299	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3299&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328047	8033041							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4886	Nc1cccc2c(Nc3cccc(Br)c3)ncnc12	InChI=1S/C14H11BrN4/c15-9-3-1-4-10(7-9)19-14-11-5-2-6-12(16)13(11)17-8-18-14/h1-8H,16H2,(H,17,18,19)	WQZUDZYVETUDRB-UHFFFAOYSA-N	3300	4-N-(3-bromophenyl)quinazoline-4,8-diamine::4-Anilinoquinazoline deriv. 51	Epidermal growth factor receptor	Homo sapiens		 105							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3300	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328048	8033042							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4887	COc1cccc2c(Nc3cccc(Br)c3)ncnc12	InChI=1S/C15H12BrN3O/c1-20-13-7-3-6-12-14(13)17-9-18-15(12)19-11-5-2-4-10(16)8-11/h2-9H,1H3,(H,17,18,19)	WCJIZSYSAHKAQF-UHFFFAOYSA-N	3301	N-(3-bromophenyl)-8-methoxyquinazolin-4-amine::4-Anilinoquinazoline deriv. 52	Epidermal growth factor receptor	Homo sapiens		 974							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3301	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3301&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328049	8033043							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4888	Oc1cc2ncnc(Nc3cccc(Br)c3)c2cc1O	InChI=1S/C14H10BrN3O2/c15-8-2-1-3-9(4-8)18-14-10-5-12(19)13(20)6-11(10)16-7-17-14/h1-7,19-20H,(H,16,17,18)	CZMCXMIIVHUIPE-UHFFFAOYSA-N	3302	4-[(3-bromophenyl)amino]quinazoline-6,7-diol::44 (3-Bromophenyl)amino]-6,7-dihydroxyquinazoline::CHEMBL93032::4-Anilinoquinazoline deriv. 53	Epidermal growth factor receptor	Homo sapiens		 0.17							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3302	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3302&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328050	8033044		CHEMBL93032					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4889	Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N	InChI=1S/C14H12BrN5/c15-8-2-1-3-9(4-8)20-14-10-5-11(16)12(17)6-13(10)18-7-19-14/h1-7H,16-17H2,(H,18,19,20)	ADXSZLCTQCWMTE-UHFFFAOYSA-N	3303	4-N-(3-bromophenyl)quinazoline-4,6,7-triamine::CHEMBL328216::4[ (3-Bromophenyl)aminol-6,7-diaminoquinazoline::4-Anilinoquinazoline deriv. 54	Epidermal growth factor receptor	Homo sapiens		 0.12							Curated from the literature by BindingDB	10.1021/jm00018a008	10.7270/Q2319T3K	7658435	aid1795505		Rewcastle, GW; Denny, WA; Bridges, AJ; Zhou, H; Cody, DR; McMichael, A; Fry, DW	9/1/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3303	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3303&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2426	8033045		CHEMBL328216					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4891	Nc1cc2ncnc(Nc3ccccc3)c2cn1	InChI=1S/C13H11N5/c14-12-6-11-10(7-15-12)13(17-8-16-11)18-9-4-2-1-3-5-9/h1-8H,(H2,14,15)(H,16,17,18)	PFOCXCZOPREBSG-UHFFFAOYSA-N	3304	7-amino-4-(phenylamino)pyrido[4,3-d]pyrimidine::4-N-phenylpyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7a	Epidermal growth factor receptor	Homo sapiens		 250					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3304	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3304&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328051	8033046							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4892	Nc1cc2ncnc(Nc3ccccc3[N+]([O-])=O)c2cn1	InChI=1S/C13H10N6O2/c14-12-5-10-8(6-15-12)13(17-7-16-10)18-9-3-1-2-4-11(9)19(20)21/h1-7H,(H2,14,15)(H,16,17,18)	FPEUMZRLYARFMA-UHFFFAOYSA-N	3305	7-amino-4-[(2-nitrophenyl)amino]pyrido[4,3-d]pyrimidine::4-N-(2-nitrophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7b	Epidermal growth factor receptor	Homo sapiens		 1250					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3305	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3305&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328052	8033047							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4893	Nc1cc2ncnc(Nc3cccc(c3)[N+]([O-])=O)c2cn1	InChI=1S/C13H10N6O2/c14-12-5-11-10(6-15-12)13(17-7-16-11)18-8-2-1-3-9(4-8)19(20)21/h1-7H,(H2,14,15)(H,16,17,18)	BMZXYZGEVIZRKF-UHFFFAOYSA-N	3306	4-N-(3-nitrophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-nitrophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7c	Epidermal growth factor receptor	Homo sapiens		 40					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3306	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3306&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328053	8033048							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4894	Nc1cc2ncnc(Nc3ccc(cc3)[N+]([O-])=O)c2cn1	InChI=1S/C13H10N6O2/c14-12-5-11-10(6-15-12)13(17-7-16-11)18-8-1-3-9(4-2-8)19(20)21/h1-7H,(H2,14,15)(H,16,17,18)	PADVQKGIUWLZBS-UHFFFAOYSA-N	3307	4-N-(4-nitrophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Amino-4-[(4-nitrophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7d	Epidermal growth factor receptor	Homo sapiens		 65000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3307	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3307&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328054	8033049							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4895	Nc1cc2ncnc(Nc3ccccc3Br)c2cn1	InChI=1S/C13H10BrN5/c14-9-3-1-2-4-10(9)19-13-8-6-16-12(15)5-11(8)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	JNVDKMMKSJKSEG-UHFFFAOYSA-N	3308	7-amino-4-[(2-bromophenyl)amino]pyrido[4,3-d]pyrimidine::4-N-(2-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7e	Epidermal growth factor receptor	Homo sapiens		 240					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3308	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3308&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328055	8033050							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4896	Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	SFUYILVZGXHCDG-UHFFFAOYSA-N	3309	4-N-(3-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidine::CHEMBL52076::7-Aminopyrido[4,3-d]pyrimidine 7f	Epidermal growth factor receptor	Homo sapiens		 10					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			382059	8033051		CHEMBL52076					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4897	Nc1cc2ncnc(Nc3ccc(Br)cc3)c2cn1	InChI=1S/C13H10BrN5/c14-8-1-3-9(4-2-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	YJJIALJNKYISIO-UHFFFAOYSA-N	3310	7-amino-4-[(4-bromophenyl)amino]pyrido[4,3-d]pyrimidine::4-N-(4-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7g	Epidermal growth factor receptor	Homo sapiens		 90					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3310	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3310&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328056	8033052							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4898	Nc1cc2ncnc(Nc3ccccc3C(F)(F)F)c2cn1	InChI=1S/C14H10F3N5/c15-14(16,17)9-3-1-2-4-10(9)22-13-8-6-19-12(18)5-11(8)20-7-21-13/h1-7H,(H2,18,19)(H,20,21,22)	UTTGFVAYAIXJEI-UHFFFAOYSA-N	3311	7-Amino-4-[2-(trifluoromethyl)phenyl]amino]pyrido[4,3-d]pyrimidine::4-N-[2-(trifluoromethyl)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7h	Epidermal growth factor receptor	Homo sapiens		 10000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3311	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3311&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328057	8033053							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4899	Nc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cn1	InChI=1S/C14H10F3N5/c15-14(16,17)8-2-1-3-9(4-8)22-13-10-6-19-12(18)5-11(10)20-7-21-13/h1-7H,(H2,18,19)(H,20,21,22)	UCCQIOAGMXPOET-UHFFFAOYSA-N	3312	7-amino-4-[[3-(trifluoromethyl)phenyl]amino]pyrido[4,3-d]pyrimidine::4-N-[3-(trifluoromethyl)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7i	Epidermal growth factor receptor	Homo sapiens		 15					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328058	8033054							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4900	Nc1cc2ncnc(Nc3ccc(cc3)C(F)(F)F)c2cn1	InChI=1S/C14H10F3N5/c15-14(16,17)8-1-3-9(4-2-8)22-13-10-6-19-12(18)5-11(10)20-7-21-13/h1-7H,(H2,18,19)(H,20,21,22)	NDNQFBSGWVDUBN-UHFFFAOYSA-N	3313	4-N-[4-(trifluoromethyl)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[4-(trifluoromethy1)phenyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7j	Epidermal growth factor receptor	Homo sapiens		 4700					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3313	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3313&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328059	8033055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4901	COc1ccccc1Nc1ncnc2cc(N)ncc12	InChI=1S/C14H13N5O/c1-20-12-5-3-2-4-10(12)19-14-9-7-16-13(15)6-11(9)17-8-18-14/h2-8H,1H3,(H2,15,16)(H,17,18,19)	ZHZNAKBOBOUWQI-UHFFFAOYSA-N	3314	4-N-(2-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(2-methoxyphenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7k	Epidermal growth factor receptor	Homo sapiens		 3710					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3314	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3314&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328060	8033056							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4902	COc1cccc(Nc2ncnc3cc(N)ncc23)c1	InChI=1S/C14H13N5O/c1-20-10-4-2-3-9(5-10)19-14-11-7-16-13(15)6-12(11)17-8-18-14/h2-8H,1H3,(H2,15,16)(H,17,18,19)	CVTRQPCTVZAMDM-UHFFFAOYSA-N	3315	4-N-(3-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-methoxyphenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7l	Epidermal growth factor receptor	Homo sapiens		 130					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3315	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3315&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328061	8033057							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4903	COc1ccc(Nc2ncnc3cc(N)ncc23)cc1	InChI=1S/C14H13N5O/c1-20-10-4-2-9(3-5-10)19-14-11-7-16-13(15)6-12(11)17-8-18-14/h2-8H,1H3,(H2,15,16)(H,17,18,19)	VVRKAQKHXCWYBU-UHFFFAOYSA-N	3316	4-N-(4-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(4-methoxyphenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7m	Epidermal growth factor receptor	Homo sapiens		 670					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3316	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3316&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328062	8033058							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4904	Nc1cc2ncnc(Nc3ccccc3N)c2cn1	InChI=1S/C13H12N6/c14-9-3-1-2-4-10(9)19-13-8-6-16-12(15)5-11(8)17-7-18-13/h1-7H,14H2,(H2,15,16)(H,17,18,19)	VPHARLVYHLVLLI-UHFFFAOYSA-N	3317	4-N-(2-aminophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Amino-4-[(2-aminophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7n	Epidermal growth factor receptor	Homo sapiens		 5250					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3317	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3317&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328063	8033059							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4905	Nc1cccc(Nc2ncnc3cc(N)ncc23)c1	InChI=1S/C13H12N6/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,14H2,(H2,15,16)(H,17,18,19)	LLVSJVCHNFCBSQ-UHFFFAOYSA-N	3318	4-N-(3-aminophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-aminophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7o	Epidermal growth factor receptor	Homo sapiens		 1550					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3318	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3318&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328064	8033060							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4906	Nc1ccc(Nc2ncnc3cc(N)ncc23)cc1	InChI=1S/C13H12N6/c14-8-1-3-9(4-2-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,14H2,(H2,15,16)(H,17,18,19)	JLVREWBDAZGUPU-UHFFFAOYSA-N	3319	4-N-(4-aminophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Amino-4-[(4-aminophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7p	Epidermal growth factor receptor	Homo sapiens		 5900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3319	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3319&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328065	8033061							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4907	CN(C)c1ccccc1Nc1ncnc2cc(N)ncc12	InChI=1S/C15H16N6/c1-21(2)13-6-4-3-5-11(13)20-15-10-8-17-14(16)7-12(10)18-9-19-15/h3-9H,1-2H3,(H2,16,17)(H,18,19,20)	JWIBIIOOQVPSQE-UHFFFAOYSA-N	3320	4-N-[2-(dimethylamino)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[2-(dimethylamino)phenyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7q	Epidermal growth factor receptor	Homo sapiens		 69000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3320	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3320&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328066	8033062							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4908	CN(C)c1cccc(Nc2ncnc3cc(N)ncc23)c1	InChI=1S/C15H16N6/c1-21(2)11-5-3-4-10(6-11)20-15-12-8-17-14(16)7-13(12)18-9-19-15/h3-9H,1-2H3,(H2,16,17)(H,18,19,20)	AXWWHGKCZJFFIJ-UHFFFAOYSA-N	3321	4-N-[3-(dimethylamino)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[3-(dimethylamino)phenyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7r	Epidermal growth factor receptor	Homo sapiens		 1790							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3321	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3321&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328067	8033063							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4909	CN(C)c1ccc(Nc2ncnc3cc(N)ncc23)cc1	InChI=1S/C15H16N6/c1-21(2)11-5-3-10(4-6-11)20-15-12-8-17-14(16)7-13(12)18-9-19-15/h3-9H,1-2H3,(H2,16,17)(H,18,19,20)	DJDLWERONIANEV-UHFFFAOYSA-N	3322	7-amino-4-[[4-(dimethylamino)phenyl]amino]pyrido[4,3-d]pyrimidine::4-N-[4-(dimethylamino)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7s	Epidermal growth factor receptor	Homo sapiens		 4860							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3322	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3322&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328068	8033064							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4910	Nc1cc2ncnc(Nc3cccc(F)c3)c2cn1	InChI=1S/C13H10FN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	QFPOOGRVHSRBMK-UHFFFAOYSA-N	3323	4-N-(3-fluorophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-fluorophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7t	Epidermal growth factor receptor	Homo sapiens		 840							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3323	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3323&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328069	8033065							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4911	Nc1cc2ncnc(Nc3cccc(Cl)c3)c2cn1	InChI=1S/C13H10ClN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	HOFPQFNPXSITFY-UHFFFAOYSA-N	3324	7-amino-4[(3-chlorophenyl)amino]pyrido[4,3-d]pyrimidine::4-N-(3-chlorophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7u	Epidermal growth factor receptor	Homo sapiens		 120							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3324	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3324&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328070	8033066							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4912	Nc1cc2ncnc(Nc3cccc(I)c3)c2cn1	InChI=1S/C13H10IN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	XHAMGUHNIYOUSX-UHFFFAOYSA-N	3325	4-N-(3-iodophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-iodophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7v	Epidermal growth factor receptor	Homo sapiens		 260							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3325	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3325&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328071	8033067							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4913	Nc1cc2ncnc(Nc3cccc(O)c3)c2cn1	InChI=1S/C13H11N5O/c14-12-5-11-10(6-15-12)13(17-7-16-11)18-8-2-1-3-9(19)4-8/h1-7,19H,(H2,14,15)(H,16,17,18)	UNRPCVUDZXTDLE-UHFFFAOYSA-N	3326	3-({7-aminopyrido[4,3-d]pyrimidin-4-yl}amino)phenol::7-amino-4-[(3-hydroxphenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7w	Epidermal growth factor receptor	Homo sapiens		 70							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3326	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3326&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328072	8033068							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4914	Cc1cccc(Nc2ncnc3cc(N)ncc23)c1	InChI=1S/C14H13N5/c1-9-3-2-4-10(5-9)19-14-11-7-16-13(15)6-12(11)17-8-18-14/h2-8H,1H3,(H2,15,16)(H,17,18,19)	JLJVRIZTCVMURV-UHFFFAOYSA-N	3327	4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-methylphenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7x	Epidermal growth factor receptor	Homo sapiens		 40							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3327	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3327&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328073	8033069							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4915	Nc1cc2ncnc(Nc3cccnc3)c2cn1	InChI=1S/C12H10N6/c13-11-4-10-9(6-15-11)12(17-7-16-10)18-8-2-1-3-14-5-8/h1-7H,(H2,13,15)(H,16,17,18)	ADGNXZYXXDBKGR-UHFFFAOYSA-N	3328	7-amino-4-[(3-pyridyl)amino]pyrido[4,3-d]pyrimidine::4-N-(pyridin-3-yl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7y	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3328	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3328&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328074	8033070							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4916	CC(=O)Nc1cccc(Nc2ncnc3cc(N)ncc23)c1	InChI=1S/C15H14N6O/c1-9(22)20-10-3-2-4-11(5-10)21-15-12-7-17-14(16)6-13(12)18-8-19-15/h2-8H,1H3,(H2,16,17)(H,20,22)(H,18,19,21)	HKWZDQXHGWQFAO-UHFFFAOYSA-N	3329	N-[3-({7-aminopyrido[4,3-d]pyrimidin-4-yl}amino)phenyl]acetamide::7-amino-4-[(3-acetamidophenyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 7z	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3329	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3329&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328075	8033071							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4917	CC(=O)Nc1ccc(Nc2ncnc3cc(N)ncc23)cc1	InChI=1S/C15H14N6O/c1-9(22)20-10-2-4-11(5-3-10)21-15-12-7-17-14(16)6-13(12)18-8-19-15/h2-8H,1H3,(H2,16,17)(H,20,22)(H,18,19,21)	PHWNKYYBNNWOEC-UHFFFAOYSA-N	3330	7-amino-4-[(4-acetamidophenyl)amino]pyrido[4,3-d]pyrimidine::N-[4-({7-aminopyrido[4,3-d]pyrimidin-4-yl}amino)phenyl]acetamide::7-Aminopyrido[4,3-d]pyrimidine 7aa	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3330	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3330&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328076	8033072							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4918	Nc1cc2ncnc(NCc3ccccc3)c2cn1	InChI=1S/C14H13N5/c15-13-6-12-11(8-16-13)14(19-9-18-12)17-7-10-4-2-1-3-5-10/h1-6,8-9H,7H2,(H2,15,16)(H,17,18,19)	JBRBEQRTMVYDCU-UHFFFAOYSA-N	3331	4-N-benzylpyrido[4,3-d]pyrimidine-4,7-diamine::CHEMBL300083::7-Amino-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8a	Epidermal growth factor receptor	Homo sapiens		 580							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3331	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3331&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328077	8033073		CHEMBL300083					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4919	Nc1cc2ncnc(NCc3ccccc3[N+]([O-])=O)c2cn1	InChI=1S/C14H12N6O2/c15-13-5-11-10(7-16-13)14(19-8-18-11)17-6-9-3-1-2-4-12(9)20(21)22/h1-5,7-8H,6H2,(H2,15,16)(H,17,18,19)	CJGIANITKCSLRQ-UHFFFAOYSA-N	3332	7-amino-4-[[(2-nitrophenyl)methyl]amino]pyrido[4,3-d]pyrimidine::4-N-[(2-nitrophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 8b	Epidermal growth factor receptor	Homo sapiens		 4250							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3332	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3332&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328078	8033074							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4920	Nc1cc2ncnc(NCc3cccc(c3)[N+]([O-])=O)c2cn1	InChI=1S/C14H12N6O2/c15-13-5-12-11(7-16-13)14(19-8-18-12)17-6-9-2-1-3-10(4-9)20(21)22/h1-5,7-8H,6H2,(H2,15,16)(H,17,18,19)	YTGMMGMVMUSNNJ-UHFFFAOYSA-N	3333	4-N-[(3-nitrophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[(3-nitrophenyl)methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8c	Epidermal growth factor receptor	Homo sapiens		 10100							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3333	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3333&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328079	8033075							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4921	Nc1cc2ncnc(NCc3ccc(cc3)[N+]([O-])=O)c2cn1	InChI=1S/C14H12N6O2/c15-13-5-12-11(7-16-13)14(19-8-18-12)17-6-9-1-3-10(4-2-9)20(21)22/h1-5,7-8H,6H2,(H2,15,16)(H,17,18,19)	WHFXKHSZKZPINP-UHFFFAOYSA-N	3334	7-amino-4-[[(4-nitrophenyl)methyl]amino]pyrido[4,3-d]pyrimidine::4-N-[(4-nitrophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 8d	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3334	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3334&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328080	8033076							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4922	Nc1cc2ncnc(NCc3ccccc3Br)c2cn1	InChI=1S/C14H12BrN5/c15-11-4-2-1-3-9(11)6-18-14-10-7-17-13(16)5-12(10)19-8-20-14/h1-5,7-8H,6H2,(H2,16,17)(H,18,19,20)	YPHZMMAIKSDRPX-UHFFFAOYSA-N	3335	4-N-[(2-bromophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Amino-4[[(2-bromophenyl)methy1]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8e	Epidermal growth factor receptor	Homo sapiens		 1670							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3335	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3335&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328081	8033077							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4923	Nc1cc2ncnc(NCc3cccc(Br)c3)c2cn1	InChI=1S/C14H12BrN5/c15-10-3-1-2-9(4-10)6-18-14-11-7-17-13(16)5-12(11)19-8-20-14/h1-5,7-8H,6H2,(H2,16,17)(H,18,19,20)	DSHKTWXJICRQFJ-UHFFFAOYSA-N	3336	4-N-[(3-bromophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[(3-bromophenyl)methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8f	Epidermal growth factor receptor	Homo sapiens		 1000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3336	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328082	8033078							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4924	Nc1cc2ncnc(NCc3ccc(Br)cc3)c2cn1	InChI=1S/C14H12BrN5/c15-10-3-1-9(2-4-10)6-18-14-11-7-17-13(16)5-12(11)19-8-20-14/h1-5,7-8H,6H2,(H2,16,17)(H,18,19,20)	HZIJNNGFACBXKU-UHFFFAOYSA-N	3337	4-N-[(4-bromophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[(4-bromophenyl)methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8g	Epidermal growth factor receptor	Homo sapiens		 2460							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3337	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3337&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328083	8033079							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4925	Nc1cc2ncnc(NCc3ccccc3C(F)(F)F)c2cn1	InChI=1S/C15H12F3N5/c16-15(17,18)11-4-2-1-3-9(11)6-21-14-10-7-20-13(19)5-12(10)22-8-23-14/h1-5,7-8H,6H2,(H2,19,20)(H,21,22,23)	SQDKQQSPVKUQCA-UHFFFAOYSA-N	3338	4-N-{[2-(trifluoromethyl)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[[2-(trifluoromethyl)-phenyl]methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8h	Epidermal growth factor receptor	Homo sapiens		 10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3338	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3338&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328084	8033080							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4926	Nc1cc2ncnc(NCc3cccc(c3)C(F)(F)F)c2cn1	InChI=1S/C15H12F3N5/c16-15(17,18)10-3-1-2-9(4-10)6-21-14-11-7-20-13(19)5-12(11)22-8-23-14/h1-5,7-8H,6H2,(H2,19,20)(H,21,22,23)	TZORILTWIYQZJR-UHFFFAOYSA-N	3339	4-N-{[3-(trifluoromethyl)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[[3-(trifluoromethyl)phenyl]methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8i	Epidermal growth factor receptor	Homo sapiens		 1950							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3339	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3339&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328085	8033081							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4927	Nc1cc2ncnc(NCc3ccc(cc3)C(F)(F)F)c2cn1	InChI=1S/C15H12F3N5/c16-15(17,18)10-3-1-9(2-4-10)6-21-14-11-7-20-13(19)5-12(11)22-8-23-14/h1-5,7-8H,6H2,(H2,19,20)(H,21,22,23)	BWNONDXUINKARZ-UHFFFAOYSA-N	3340	7-amino-4-[[[4-(trifluoromethyl)phenyllmethyl]amino]pyrido[4,3-d]pyrimidine::4-N-{[4-(trifluoromethyl)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 8j	Epidermal growth factor receptor	Homo sapiens		 8000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3340	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328086	8033082							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4928	COc1ccccc1CNc1ncnc2cc(N)ncc12	InChI=1S/C15H15N5O/c1-21-13-5-3-2-4-10(13)7-18-15-11-8-17-14(16)6-12(11)19-9-20-15/h2-6,8-9H,7H2,1H3,(H2,16,17)(H,18,19,20)	UIKUPKYKBYMHFU-UHFFFAOYSA-N	3341	4-N-[(2-methoxyphenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[(2-methoxyphenyl)-methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8k	Epidermal growth factor receptor	Homo sapiens		 100000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3341	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3341&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328087	8033083							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4929	COc1cccc(CNc2ncnc3cc(N)ncc23)c1	InChI=1S/C15H15N5O/c1-21-11-4-2-3-10(5-11)7-18-15-12-8-17-14(16)6-13(12)19-9-20-15/h2-6,8-9H,7H2,1H3,(H2,16,17)(H,18,19,20)	OWBQYDARFOLTFW-UHFFFAOYSA-N	3342	4-N-[(3-methoxyphenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[(3-methoxyphenyl)-methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8l	Epidermal growth factor receptor	Homo sapiens		 2870							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3342	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3342&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328088	8033084							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4930	COc1ccc(CNc2ncnc3cc(N)ncc23)cc1	InChI=1S/C15H15N5O/c1-21-11-4-2-10(3-5-11)7-18-15-12-8-17-14(16)6-13(12)19-9-20-15/h2-6,8-9H,7H2,1H3,(H2,16,17)(H,18,19,20)	WANNBVICBHCQGP-UHFFFAOYSA-N	3343	4-N-[(4-methoxyphenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[(4-methoxyphenyl)methyl]-amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8m	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3343	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3343&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328089	8033085							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4931	Nc1cc2ncnc(NCc3ccccc3N)c2cn1	InChI=1S/C14H14N6/c15-11-4-2-1-3-9(11)6-18-14-10-7-17-13(16)5-12(10)19-8-20-14/h1-5,7-8H,6,15H2,(H2,16,17)(H,18,19,20)	UOXLBDZHQKWTRJ-UHFFFAOYSA-N	3344	4-N-[(2-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Amino-4-[(2-aminophenyl)methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8n	Epidermal growth factor receptor	Homo sapiens		 230							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3344&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328090	8033086							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4932	Nc1cccc(CNc2ncnc3cc(N)ncc23)c1	InChI=1S/C14H14N6/c15-10-3-1-2-9(4-10)6-18-14-11-7-17-13(16)5-12(11)19-8-20-14/h1-5,7-8H,6,15H2,(H2,16,17)(H,18,19,20)	FIDYSXSIFTWCGR-UHFFFAOYSA-N	3345	7-amino-4-[[(3-aminophenyl)methyl]amino]pyrido[4,3-d]pyimidine::4-N-[(3-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 8o	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3345&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328091	8033087							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4933	Nc1ccc(CNc2ncnc3cc(N)ncc23)cc1	InChI=1S/C14H14N6/c15-10-3-1-9(2-4-10)6-18-14-11-7-17-13(16)5-12(11)19-8-20-14/h1-5,7-8H,6,15H2,(H2,16,17)(H,18,19,20)	HIWFHPSOFUPDSH-UHFFFAOYSA-N	3346	4-N-[(4-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[(4-aminophenyl)methyl]amino]pyrido[4,3-d]-pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8p	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3346	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3346&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328092	8033088							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4934	CN(C)c1ccccc1CNc1ncnc2cc(N)ncc12	InChI=1S/C16H18N6/c1-22(2)14-6-4-3-5-11(14)8-19-16-12-9-18-15(17)7-13(12)20-10-21-16/h3-7,9-10H,8H2,1-2H3,(H2,17,18)(H,19,20,21)	WECXGAPWWABMMK-UHFFFAOYSA-N	3347	4-N-{[2-(dimethylamino)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[[2-(dimethylamino)phenyl]methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8q	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3347&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328093	8033089							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4935	CN(C)c1cccc(CNc2ncnc3cc(N)ncc23)c1	InChI=1S/C16H18N6/c1-22(2)12-5-3-4-11(6-12)8-19-16-13-9-18-15(17)7-14(13)20-10-21-16/h3-7,9-10H,8H2,1-2H3,(H2,17,18)(H,19,20,21)	NUNYTOSAJZDUSJ-UHFFFAOYSA-N	3348	4-N-{[3-(dimethylamino)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[ [ [3-( dimethylamino)phenyl]methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8r	Epidermal growth factor receptor	Homo sapiens		 10000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3348&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328094	8033090							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4936	CN(C)c1ccc(CNc2ncnc3cc(N)ncc23)cc1	InChI=1S/C16H18N6/c1-22(2)12-5-3-11(4-6-12)8-19-16-13-9-18-15(17)7-14(13)20-10-21-16/h3-7,9-10H,8H2,1-2H3,(H2,17,18)(H,19,20,21)	GDHQNZFWQPKIKO-UHFFFAOYSA-N	3349	4-N-{[4-(dimethylamino)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[[[4-(dimethylamino)phenyl]methyl]amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8s	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00019a007	10.7270/Q2Z899M8	7562908	aid1795513		Thompson, AM; Bridges, AJ; Fry, DW; Kraker, AJ; Denny, WA	9/15/1995	2/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3349&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328095	8033091							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4937	CNC(=O)c1c(SSc2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12	InChI=1S/C22H22N4O2S2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	XUXNEGDCCYQQNC-UHFFFAOYSA-N	3350	N,1-dimethyl-2-{[1-methyl-3-(methylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1H-indole-3-carboxamide::CHEMBL342929::dithiobis(1H-indoles) deriv. 3	Epidermal growth factor receptor	Homo sapiens		 6900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3350&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328096	8033092		CHEMBL342929			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4938	NC(Cc1c(SSc2[nH]c3ccccc3c2CC(N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1	InChI=1S/C36H36N6O2S2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)	MCNYLFAPBYIPPD-UHFFFAOYSA-N	3351	CHEMBL336174::2-amino-3-[2-({3-[2-amino-2-(benzylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]-N-benzylpropanamide::dithiobis(1H-indoles) deriv. 4	Epidermal growth factor receptor	Homo sapiens		 7400					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3351	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3351&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328097	8033093		CHEMBL336174			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4939	Cn1c([Se][Se]c2c(C(=O)OC(C)(C)C)c3ccccc3n2C)c(C(=O)OC(C)(C)C)c2ccccc12	InChI=1S/C28H32N2O4Se2/c1-27(2,3)33-25(31)21-17-13-9-11-15-19(17)29(7)23(21)35-36-24-22(26(32)34-28(4,5)6)18-14-10-12-16-20(18)30(24)8/h9-16H,1-8H3	PWTGGAFLPJCGFH-UHFFFAOYSA-N	3352	tert-butyl 2-({3-[(tert-butoxy)carbonyl]-1-methyl-1H-indol-2-yl}diselanyl)-1-methyl-1H-indole-3-carboxylate::2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic acid, tert-butyl ester]::diselenobis(1H-indole) deriv. 21	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3352	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3352&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328098	8033094							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4940	Cn1c([Se][Se]c2c(C(O)=O)c3ccccc3n2C)c(C(O)=O)c2ccccc12	InChI=1S/C20H16N2O4Se2/c1-21-13-9-5-3-7-11(13)15(19(23)24)17(21)27-28-18-16(20(25)26)12-8-4-6-10-14(12)22(18)2/h3-10H,1-2H3,(H,23,24)(H,25,26)	HNEORRPIDMAPCB-UHFFFAOYSA-N	3353	2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-methyl-1H-indole-3-carboxylic acid::2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic acid]::diselenobis(1H-indole) deriv. 22	Epidermal growth factor receptor	Homo sapiens		 3500					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3353&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328099	8033095							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4941	CNC(=O)c1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12	InChI=1S/C22H22N4O2Se2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)	KKTAXCWCKSLCHF-UHFFFAOYSA-N	3354	2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxamide]::N,1-dimethyl-2-{[1-methyl-3-(methylcarbamoyl)-1H-indol-2-yl]diselanyl}-1H-indole-3-carboxamide::diselenobis(1H-indole) deriv. 23	Epidermal growth factor receptor	Homo sapiens		 6100					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3354&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328100	8033096							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4942	CCN(CC)CCNC(=O)c1c([Se][Se]c2c(C(=O)NCCN(CC)CC)c3ccccc3n2C)n(C)c2ccccc12	InChI=1S/C32H44N6O2Se2/c1-7-37(8-2)21-19-33-29(39)27-23-15-11-13-17-25(23)35(5)31(27)41-42-32-28(24-16-12-14-18-26(24)36(32)6)30(40)34-20-22-38(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	XZTHVVIRCUVGRE-UHFFFAOYSA-N	3355	N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)ethyl]carbamoyl}-1-methyl-1H-indol-2-yl)diselanyl]-1-methyl-1H-indole-3-carboxamide::2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1-methyl-1H-indole-3-carboxamide]::diselenobis(1H-indole) deriv. 24	Epidermal growth factor receptor	Homo sapiens		 4700					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3355&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328101	8033097							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4943	CNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NC)[nH]c2ccccc12	InChI=1S/C20H18N4O2Se2/c1-21-17(25)15-11-7-3-5-9-13(11)23-19(15)27-28-20-16(18(26)22-2)12-8-4-6-10-14(12)24-20/h3-10,23-24H,1-2H3,(H,21,25)(H,22,26)	SSIOMHJBYZEOEK-UHFFFAOYSA-N	3356	2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]::N-methyl-2-{[3-(methylcarbamoyl)-1H-indol-2-yl]diselanyl}-1H-indole-3-carboxamide::diselenobis(1H-indole) deriv. 25	Epidermal growth factor receptor	Homo sapiens		 13000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3356&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328102	8033098							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4944	CCN(CC)CCNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NCCN(CC)CC)[nH]c2ccccc12	InChI=1S/C30H40N6O2Se2/c1-5-35(6-2)19-17-31-27(37)25-21-13-9-11-15-23(21)33-29(25)39-40-30-26(22-14-10-12-16-24(22)34-30)28(38)32-18-20-36(7-3)8-4/h9-16,33-34H,5-8,17-20H2,1-4H3,(H,31,37)(H,32,38)	DOBDKFHLOMDQHB-UHFFFAOYSA-N	3357	N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)ethyl]carbamoyl}-1H-indol-2-yl)diselanyl]-1H-indole-3-carboxamide::2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1H-indole-3-carboxamide]::diselenobis(1H-indole) deriv. 26	Epidermal growth factor receptor	Homo sapiens		 4600					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3357	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3357&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328103	8033099							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4945	CCN(CC)CCn1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2CCN(CC)CC)c(C(=O)NC)c2ccccc12	InChI=1S/C32H44N6O2Se2/c1-7-35(8-2)19-21-37-25-17-13-11-15-23(25)27(29(39)33-5)31(37)41-42-32-28(30(40)34-6)24-16-12-14-18-26(24)38(32)22-20-36(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)	RHQWHANZNHLOIO-UHFFFAOYSA-N	3358	1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)ethyl]-3-(methylcarbamoyl)-1H-indol-2-yl}diselanyl)-N-methyl-1H-indole-3-carboxamide::2,2 -Diselenobis[1-[2-(diethylamino)ethyl]-N-methyl-1H-indole-3-carboxamide]::diselenobis(1H-indole) deriv. 27	Epidermal growth factor receptor	Homo sapiens		 6900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3358&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328104	8033100							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4946	FC(F)(F)C(=O)N[C@H](Cc1c([Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r|	InChI=1S/C40H34F6N6O4Se/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)	WZACGJSPDNLOEJ-UHFFFAOYSA-N	3359	(2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2-(2,2,2-trifluoroacetamido)ethyl]-1H-indol-2-yl}selanyl)-1H-indol-3-yl]-2-(2,2,2-trifluoroacetamido)propanamide::[R-(R*,R*)]-2,2 -selenobis[N-(phenylmethyl)-alpha-[(trifluoroacetyl)amino]-1H-indole-3-propanamide]::diselenobis(1H-indole) deriv. 30a	Epidermal growth factor receptor	Homo sapiens		>50000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3359	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3359&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328105	8033101							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4947	FC(F)(F)C(=O)N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r|	InChI=1S/C40H34F6N6O4Se2/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-58-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)	FWFCALLHZITRMJ-UHFFFAOYSA-N	3360	(2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2-(2,2,2-trifluoroacetamido)ethyl]-1H-indol-2-yl}diselanyl)-1H-indol-3-yl]-2-(2,2,2-trifluoroacetamido)propanamide::[R-(R*,R*)]-2,2 -diselenobis[N-(phenylmethyl)-alpha-[(trifluoroacetyl)amino]-1H-indole-3-propanamide]::diselenobis(1H-indole) deriv. 32a	Epidermal growth factor receptor	Homo sapiens		 7000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3360	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3360&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328106	8033102							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4948	N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r|	InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)	NHZUIHJUVWDGGV-UHFFFAOYSA-N	3361	(2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarbamoyl)ethyl]-1H-indol-2-yl}diselanyl)-1H-indol-3-yl]-N-benzylpropanamide::diselenobis(1H-indole) deriv. 33	Epidermal growth factor receptor	Homo sapiens		 900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3361	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3361&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328107	8033103							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
4949	N[C@@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1 |r|	InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)	NHZUIHJUVWDGGV-UHFFFAOYSA-N	3362	(2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarbamoyl)ethyl]-1H-indol-2-yl}diselanyl)-1H-indol-3-yl]-N-benzylpropanamide::diselenobis(1H-indole) deriv. 34	Epidermal growth factor receptor	Homo sapiens		 1300					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960689b	10.7270/Q2TH8JWJ	9046331	aid1795518		Showalter, HD; Sercel, AD; Leja, BM; Wolfangel, CD; Ambroso, LA; Elliott, WL; Fry, DW; Kraker, AJ; Howard, CT; Lu, GH; Moore, CW; Nelson, JM; Roberts, BJ; Vincent, PW; Denny, WA; Thompson, AM	2/14/1997	2/22/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3362	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3362&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328108	8033104							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5263	N(c1ccccc1)c1ncnc2ccccc12	InChI=1S/C14H11N3/c1-2-6-11(7-3-1)17-14-12-8-4-5-9-13(12)15-10-16-14/h1-10H,(H,15,16,17)	MTSNDBYBIZSILH-UHFFFAOYSA-N	3259	N-phenylquinazolin-4-amine::CHEMBL289959::4-Anilino quinazoline deriv. 10	Epidermal growth factor receptor	Homo sapiens		 344					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3259	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3259&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			324081	8033001		CHEMBL289959					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5264	Fc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10FN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	QXULSIJDISMUNF-UHFFFAOYSA-N	3503	CHEMBL92985::N-(3-fluorophenyl)quinazolin-4-amine::PD153035 Analog 2	Epidermal growth factor receptor	Homo sapiens		 56					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3503&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			735124	8033238		CHEMBL92985					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5265	Clc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10ClN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	ZKKVUIPXPPDIRD-UHFFFAOYSA-N	3263	CHEMBL329672::N-(3-chlorophenyl)quinazolin-4-amine::CHEMBL555321::4-Anilino quinazoline deriv. 14	Epidermal growth factor receptor	Homo sapiens		 23					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3263	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3263&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			128872	8033005		CHEMBL555321CHEMBL329672					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5266	Brc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10BrN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	SUTRLYZWRGPLSJ-UHFFFAOYSA-N	3264	CHEMBL290096::N-(3-bromophenyl)quinazolin-4-amine::4-Anilino quinazoline deriv. 15	Epidermal growth factor receptor	Homo sapiens		 27					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3264	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3264&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			735125	8033006		CHEMBL290096					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5267	Ic1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10IN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	LCUWAJDEGKZDMI-UHFFFAOYSA-N	3265	CHEMBL92825::N-(3-iodophenyl)quinazolin-4-amine::4-Anilino quinazoline deriv. 16	Epidermal growth factor receptor	Homo sapiens		 80					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3265	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3265&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			735126	8033007		CHEMBL92825					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5268	FC(F)(F)c1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C15H10F3N3/c16-15(17,18)10-4-3-5-11(8-10)21-14-12-6-1-2-7-13(12)19-9-20-14/h1-9H,(H,19,20,21)	VCOMYMMMFREKQC-UHFFFAOYSA-N	3266	CHEMBL92824::N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine::4-Anilino quinazoline deriv. 17	Epidermal growth factor receptor	Homo sapiens		 577					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3266	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3266&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			651672	8033008		CHEMBL92824					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5269	COc1ccc2ncnc(Nc3ccccc3)c2c1	InChI=1S/C15H13N3O/c1-19-12-7-8-14-13(9-12)15(17-10-16-14)18-11-5-3-2-4-6-11/h2-10H,1H3,(H,16,17,18)	GKRKTKNUATZSTP-UHFFFAOYSA-N	3508	CHEMBL328879::6-methoxy-N-phenylquinazolin-4-amine::PD153035 Analog 7	Epidermal growth factor receptor	Homo sapiens		 55					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3508&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328186	8033239		CHEMBL328879					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5270	COc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C15H12BrN3O/c1-20-12-5-6-14-13(8-12)15(18-9-17-14)19-11-4-2-3-10(16)7-11/h2-9H,1H3,(H,17,18,19)	LDTMDWOXHYGMAM-UHFFFAOYSA-N	3295	CHEMBL52197::N-(3-bromophenyl)-6-methoxyquinazolin-4-amine::4-Anilinoquinazoline deriv. 46	Epidermal growth factor receptor	Homo sapiens		 30					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3295	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3295&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328043	8033037		CHEMBL52197					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5271	Nc1ccc2ncnc(Nc3ccccc3)c2c1	InChI=1S/C14H12N4/c15-10-6-7-13-12(8-10)14(17-9-16-13)18-11-4-2-1-3-5-11/h1-9H,15H2,(H,16,17,18)	MJMYCJSNBBYTCT-UHFFFAOYSA-N	3510	CHEMBL89940::4-N-phenylquinazoline-4,6-diamine::PD153035 Analog 9	Epidermal growth factor receptor	Homo sapiens		 770					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3510&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328187	8033240		CHEMBL89940					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5272	Nc1ccc2ncnc(Nc3cccc(c3)C(F)(F)F)c2c1	InChI=1S/C15H11F3N4/c16-15(17,18)9-2-1-3-11(6-9)22-14-12-7-10(19)4-5-13(12)20-8-21-14/h1-8H,19H2,(H,20,21,22)	DLVMGJPGJHCIJW-UHFFFAOYSA-N	3511	4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,6-diamine::CHEMBL328244::PD153035 Analog 10	Epidermal growth factor receptor	Homo sapiens		 574					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3511&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328188	8033241		CHEMBL328244					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5273	Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C14H11BrN4/c15-9-2-1-3-11(6-9)19-14-12-7-10(16)4-5-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	IZQHULBHKPGOAP-UHFFFAOYSA-N	3294	CHEMBL52765::4-N-(3-bromophenyl)quinazoline-4,6-diamine::Anilinoquinazoline, 4b::4-Anilinoquinazoline deriv. 45	Epidermal growth factor receptor	Homo sapiens		 0.78					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328042	8033036		CHEMBL52765					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5274	[O-][N+](=O)c1ccc2ncnc(Nc3ccccc3)c2c1	InChI=1S/C14H10N4O2/c19-18(20)11-6-7-13-12(8-11)14(16-9-15-13)17-10-4-2-1-3-5-10/h1-9H,(H,15,16,17)	LJMGWHXMJIZVDQ-UHFFFAOYSA-N	3513	6-nitro-N-phenylquinazolin-4-amine::CHEMBL328295::PD153035 Analog 12	Epidermal growth factor receptor	Homo sapiens		 5000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3513&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328189	8033242		CHEMBL328295					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5275	[O-][N+](=O)c1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C14H9BrN4O2/c15-9-2-1-3-10(6-9)18-14-12-7-11(19(20)21)4-5-13(12)16-8-17-14/h1-8H,(H,16,17,18)	MAVKGSSRIBVAGI-UHFFFAOYSA-N	3293	CHEMBL329161::N-(3-bromophenyl)-6-nitroquinazolin-4-amine::4-Anilinoquinazoline deriv. 44	Epidermal growth factor receptor	Homo sapiens		 900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3293	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3293&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328041	8033035		CHEMBL329161					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5276	[O-][N+](=O)c1ccc2ncnc(Nc3cccc(c3)C(F)(F)F)c2c1	InChI=1S/C15H9F3N4O2/c16-15(17,18)9-2-1-3-10(6-9)21-14-12-7-11(22(23)24)4-5-13(12)19-8-20-14/h1-8H,(H,19,20,21)	FKOOZPWZRRDRTK-UHFFFAOYSA-N	3515	6-nitro-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine::CHEMBL321511::PD153035 Analog 14	Epidermal growth factor receptor	Homo sapiens		>10000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3515&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3564138	8033243		CHEMBL321511					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5277	COc1ccc2c(Nc3ccccc3)ncnc2c1	InChI=1S/C15H13N3O/c1-19-12-7-8-13-14(9-12)16-10-17-15(13)18-11-5-3-2-4-6-11/h2-10H,1H3,(H,16,17,18)	LHBIFPBTEJYQLV-UHFFFAOYSA-N	3516	CHEMBL92398::7-methoxy-N-phenylquinazolin-4-amine::PD153035 Analog 15	Epidermal growth factor receptor	Homo sapiens		 120					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3516&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328190	8033244		CHEMBL92398					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5278	COc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C15H12BrN3O/c1-20-12-5-6-13-14(8-12)17-9-18-15(13)19-11-4-2-3-10(16)7-11/h2-9H,1H3,(H,17,18,19)	CDWGVMQLDOQALI-UHFFFAOYSA-N	3298	N-(3-bromophenyl)-7-methoxyquinazolin-4-amine::CHEMBL93181::4-Anilinoquinazoline deriv. 49	Epidermal growth factor receptor	Homo sapiens		 10					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3298	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3298&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328046	8033040		CHEMBL93181					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5279	Nc1ccc2c(Nc3ccccc3)ncnc2c1	InChI=1S/C14H12N4/c15-10-6-7-12-13(8-10)16-9-17-14(12)18-11-4-2-1-3-5-11/h1-9H,15H2,(H,16,17,18)	WYKOALHWZONWJR-UHFFFAOYSA-N	3518	CHEMBL330224::4-N-phenylquinazoline-4,7-diamine::PD153035 Analog 17	Epidermal growth factor receptor	Homo sapiens		 100					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3518&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328191	8033245		CHEMBL330224					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5280	Nc1ccc2c(Nc3cccc(F)c3)ncnc2c1	InChI=1S/C14H11FN4/c15-9-2-1-3-11(6-9)19-14-12-5-4-10(16)7-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	IMISPZIADMWUAH-UHFFFAOYSA-N	3519	CHEMBL93966::4-N-(3-fluorophenyl)quinazoline-4,7-diamine::PD153035 Analog 18	Epidermal growth factor receptor	Homo sapiens		 2					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3519&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328192	8033246		CHEMBL93966					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5281	Nc1ccc2c(Nc3cccc(Cl)c3)ncnc2c1	InChI=1S/C14H11ClN4/c15-9-2-1-3-11(6-9)19-14-12-5-4-10(16)7-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	SHJIAUOHYKFYCU-UHFFFAOYSA-N	3520	4-N-(3-chlorophenyl)quinazoline-4,7-diamine::CHEMBL328955::PD153035 Analog 19	Epidermal growth factor receptor	Homo sapiens		 0.25							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3520&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328193	8033247		CHEMBL328955					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5282	Nc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C14H11BrN4/c15-9-2-1-3-11(6-9)19-14-12-5-4-10(16)7-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	GHVBIROTJQDRQB-UHFFFAOYSA-N	3297	4-N-(3-bromophenyl)quinazoline-4,7-diamine::7-Amino-4-[(3-bromophenyl)aminolquinazoline::CHEMBL420624::4-Anilinoquinazoline deriv. 48	Epidermal growth factor receptor	Homo sapiens		 0.1							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3297	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3297&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328045	8033039		CHEMBL420624					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5283	Nc1ccc2c(Nc3cccc(I)c3)ncnc2c1	InChI=1S/C14H11IN4/c15-9-2-1-3-11(6-9)19-14-12-5-4-10(16)7-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	CNTUNPKRAPUANH-UHFFFAOYSA-N	3522	CHEMBL91980::4-N-(3-iodophenyl)quinazoline-4,7-diamine::PD153035 Analog 21	Epidermal growth factor receptor	Homo sapiens		 0.35							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3522&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328194	8033248		CHEMBL91980					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5284	Nc1ccc2c(Nc3cccc(c3)C(F)(F)F)ncnc2c1	InChI=1S/C15H11F3N4/c16-15(17,18)9-2-1-3-11(6-9)22-14-12-5-4-10(19)7-13(12)20-8-21-14/h1-8H,19H2,(H,20,21,22)	BUWHCUHUJIETCP-UHFFFAOYSA-N	3523	CHEMBL433205::4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,7-diamine::PD153035 Analog 22	Epidermal growth factor receptor	Homo sapiens		 3.3							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3523&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328195	8033249		CHEMBL433205					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5285	[O-][N+](=O)c1ccc2c(Nc3ccccc3)ncnc2c1	InChI=1S/C14H10N4O2/c19-18(20)11-6-7-12-13(8-11)15-9-16-14(12)17-10-4-2-1-3-5-10/h1-9H,(H,15,16,17)	FHPNEDYOQKPVMZ-UHFFFAOYSA-N	3524	7-nitro-N-phenylquinazolin-4-amine::CHEMBL91914::PD153035 Analog 23	Epidermal growth factor receptor	Homo sapiens		 12000							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3524&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328196	8033250		CHEMBL91914					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5286	[O-][N+](=O)c1ccc2c(Nc3cccc(F)c3)ncnc2c1	InChI=1S/C14H9FN4O2/c15-9-2-1-3-10(6-9)18-14-12-5-4-11(19(20)21)7-13(12)16-8-17-14/h1-8H,(H,16,17,18)	HQIGZYYYFPXURI-UHFFFAOYSA-N	3525	N-(3-fluorophenyl)-7-nitroquinazolin-4-amine::CHEMBL329183::PD153035 Analog 24	Epidermal growth factor receptor	Homo sapiens		 6100							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3525&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328197	8033251		CHEMBL329183					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5287	[O-][N+](=O)c1ccc2c(Nc3cccc(Cl)c3)ncnc2c1	InChI=1S/C14H9ClN4O2/c15-9-2-1-3-10(6-9)18-14-12-5-4-11(19(20)21)7-13(12)16-8-17-14/h1-8H,(H,16,17,18)	PFCDJDCJBTXAJZ-UHFFFAOYSA-N	3526	N-(3-chlorophenyl)-7-nitroquinazolin-4-amine::CHEMBL93635::PD153035 Analog 25	Epidermal growth factor receptor	Homo sapiens		 810							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3526&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328198	8033252		CHEMBL93635					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5288	[O-][N+](=O)c1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C14H9BrN4O2/c15-9-2-1-3-10(6-9)18-14-12-5-4-11(19(20)21)7-13(12)16-8-17-14/h1-8H,(H,16,17,18)	RZBBKHCMKJSCKV-UHFFFAOYSA-N	3296	CHEMBL94275::4-[(3-Bromophenyl)amino]-7-nitroquinazoline::N-(3-bromophenyl)-7-nitroquinazolin-4-amine::4-Anilinoquinazoline deriv. 47	Epidermal growth factor receptor	Homo sapiens		 1000							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3296	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3296&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328044	8033038		CHEMBL94275					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5289	[O-][N+](=O)c1ccc2c(Nc3cccc(I)c3)ncnc2c1	InChI=1S/C14H9IN4O2/c15-9-2-1-3-10(6-9)18-14-12-5-4-11(19(20)21)7-13(12)16-8-17-14/h1-8H,(H,16,17,18)	FFODKADEKHPVKK-UHFFFAOYSA-N	3528	N-(3-iodophenyl)-7-nitroquinazolin-4-amine::CHEMBL93284::PD153035 Analog 27	Epidermal growth factor receptor	Homo sapiens		 540							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3528&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328199	8033253		CHEMBL93284					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5290	[O-][N+](=O)c1ccc2c(Nc3cccc(c3)C(F)(F)F)ncnc2c1	InChI=1S/C15H9F3N4O2/c16-15(17,18)9-2-1-3-10(6-9)21-14-12-5-4-11(22(23)24)7-13(12)19-8-20-14/h1-8H,(H,19,20,21)	VMGLSQQSTMVBST-UHFFFAOYSA-N	3529	7-nitro-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine::CHEMBL94432::PD153035 Analog 28	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3529&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328200	8033254		CHEMBL94432					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5291	COc1cc2ncnc(Nc3ccccc3)c2cc1OC	InChI=1S/C16H15N3O2/c1-20-14-8-12-13(9-15(14)21-2)17-10-18-16(12)19-11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,19)	MJKCGAHOCZLYDG-UHFFFAOYSA-N	3530	6,7-dimethoxy-N-phenylquinazolin-4-amine::CHEMBL542484::CHEMBL94191::PD153035 Analog 29	Epidermal growth factor receptor	Homo sapiens		 29							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3530&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3798	8033255		CHEMBL94191CHEMBL542484					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5292	COc1cc2ncnc(Nc3cccc(F)c3)c2cc1OC	InChI=1S/C16H14FN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	DFWBDVRBHHFDNZ-UHFFFAOYSA-N	3531	CHEMBL541586::N-(3-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL94431::PD153035 Analog 30	Epidermal growth factor receptor	Homo sapiens		 3.8							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1474883	8033256		CHEMBL94431CHEMBL541586					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5293	COc1cc2c(cc1OC)ncnc2Nc3cccc(c3)Cl	InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	GFNNBHLJANVSQV-UHFFFAOYSA-N	3532	CHEMBL7917::CHEMBL540068::N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035 Analog 31	Epidermal growth factor receptor	Homo sapiens		 0.31							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3532&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0TO	4FEX	2051	8033257		CHEMBL540068CHEMBL7917					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5295	COc1cc2ncnc(Nc3cccc(I)c3)c2cc1OC	InChI=1S/C16H14IN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	FGCLAQLIXMAIHT-UHFFFAOYSA-N	3533	CHEMBL1204305::N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL96065::PD153035 Analog 33	Epidermal growth factor receptor	Homo sapiens		 0.89							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328201	8033258		CHEMBL96065CHEMBL1204305					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5296	COc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cc1OC	InChI=1S/C17H14F3N3O2/c1-24-14-7-12-13(8-15(14)25-2)21-9-22-16(12)23-11-5-3-4-10(6-11)17(18,19)20/h3-9H,1-2H3,(H,21,22,23)	KEQCEKUDWPXRRQ-UHFFFAOYSA-N	3534	6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine::CHEMBL316064::PD153035 Analog 34	Epidermal growth factor receptor	Homo sapiens		 0.24							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3534&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328202	8033259		CHEMBL316064					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5297	CNc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C15H13BrN4/c1-17-11-5-6-14-13(8-11)15(19-9-18-14)20-12-4-2-3-10(16)7-12/h2-9,17H,1H3,(H,18,19,20)	KFBKCZIAECRELC-UHFFFAOYSA-N	3535	4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diamine::CHEMBL50344::4-[(3-Bromophenyl)amino]-6-(methylamino)quinazoline::PD153035 Analog 35	Epidermal growth factor receptor	Homo sapiens		 4							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328203	8033260		CHEMBL50344					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5298	CN(C)c1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C16H15BrN4/c1-21(2)13-6-7-15-14(9-13)16(19-10-18-15)20-12-5-3-4-11(17)8-12/h3-10H,1-2H3,(H,18,19,20)	BNMOXMJDRLQWOW-UHFFFAOYSA-N	3536	4-N-(3-bromophenyl)-6-N,6-N-dimethylquinazoline-4,6-diamine::CHEMBL52015::PD153035 Analog 36	Epidermal growth factor receptor	Homo sapiens		 84							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3536&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328204	8033261		CHEMBL52015					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5299	COC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C16H13BrN4O2/c1-23-16(22)21-12-5-6-14-13(8-12)15(19-9-18-14)20-11-4-2-3-10(17)7-11/h2-9H,1H3,(H,21,22)(H,18,19,20)	RGKYDFXVADGYLB-UHFFFAOYSA-N	3537	CHEMBL328691::PD153035 Analog::methyl N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}carbamate::PD153035 Analog 37	Epidermal growth factor receptor	Homo sapiens		 12							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3537&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328205	8033262		CHEMBL328691					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5300	Oc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C14H10BrN3O/c15-9-2-1-3-10(6-9)18-14-12-5-4-11(19)7-13(12)16-8-17-14/h1-8,19H,(H,16,17,18)	XOLOBKIXFCWGJY-UHFFFAOYSA-N	3538	PD153035 Analog::4-[(3-bromophenyl)amino]quinazolin-7-ol::CHEMBL93302::PD153035 Analog 38	Epidermal growth factor receptor	Homo sapiens		 4.7							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328206	8033263		CHEMBL93302					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5301	CC(=O)Nc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C16H13BrN4O/c1-10(22)20-13-5-6-14-15(8-13)18-9-19-16(14)21-12-4-2-3-11(17)7-12/h2-9H,1H3,(H,20,22)(H,18,19,21)	QKWCLFRBLRJXQM-UHFFFAOYSA-N	3539	CHEMBL93461::N-{4-[(3-bromophenyl)amino]quinazolin-7-yl}acetamide::PD153035 Analog::7-Acetamido-4-[(3-bromophenyl)amino]quinazoline::PD153035 Analog 39	Epidermal growth factor receptor	Homo sapiens		 40							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328207	8033264		CHEMBL93461					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5302	CNc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C15H13BrN4/c1-17-11-5-6-13-14(8-11)18-9-19-15(13)20-12-4-2-3-10(16)7-12/h2-9,17H,1H3,(H,18,19,20)	NJCGPPRBJLJTPA-UHFFFAOYSA-N	3540	CHEMBL92812::4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diamine::PD153035 Analog::4-[(3-Bromophenyl)amino]-7-(methylamino)quinazoline::PD153035 Analog 40	Epidermal growth factor receptor	Homo sapiens		 7							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328208	8033265		CHEMBL92812					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5303	CCNc1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C16H15BrN4/c1-2-18-12-6-7-14-15(9-12)19-10-20-16(14)21-13-5-3-4-11(17)8-13/h3-10,18H,2H2,1H3,(H,19,20,21)	GXYLLTHBINHTRN-UHFFFAOYSA-N	3541	4-N-(3-bromophenyl)-7-N-ethylquinazoline-4,7-diamine::CHEMBL420254::PD153035 Analog 41	Epidermal growth factor receptor	Homo sapiens		 12							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3541&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328209	8033266		CHEMBL420254					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5304	CN(C)c1ccc2c(Nc3cccc(Br)c3)ncnc2c1	InChI=1S/C16H15BrN4/c1-21(2)13-6-7-14-15(9-13)18-10-19-16(14)20-12-5-3-4-11(17)8-12/h3-10H,1-2H3,(H,18,19,20)	OGYJJQMXMIANLJ-UHFFFAOYSA-N	3542	4-N-(3-bromophenyl)-7-N,7-N-dimethylquinazoline-4,7-diamine::CHEMBL90013::PD153035 Analog 42	Epidermal growth factor receptor	Homo sapiens		 11							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328210	8033267		CHEMBL90013					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5305	Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N	InChI=1S/C14H12BrN5/c15-8-2-1-3-9(4-8)20-14-10-5-11(16)12(17)6-13(10)18-7-19-14/h1-7H,16-17H2,(H,18,19,20)	ADXSZLCTQCWMTE-UHFFFAOYSA-N	3303	4-N-(3-bromophenyl)quinazoline-4,6,7-triamine::CHEMBL328216::4[ (3-Bromophenyl)aminol-6,7-diaminoquinazoline::4-Anilinoquinazoline deriv. 54	Epidermal growth factor receptor	Homo sapiens		 0.12							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3303	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3303&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2426	8033045		CHEMBL328216					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5306	CNc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N	InChI=1S/C15H14BrN5/c1-18-14-7-13-11(6-12(14)17)15(20-8-19-13)21-10-4-2-3-9(16)5-10/h2-8,18H,17H2,1H3,(H,19,20,21)	WUWMKQIRTKOCMN-UHFFFAOYSA-N	3544	4-N-(3-bromophenyl)-7-N-methylquinazoline-4,6,7-triamine::CHEMBL92937::PD153035 Analog 44	Epidermal growth factor receptor	Homo sapiens		 0.69							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3544	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4706	8033268		CHEMBL92937					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5307	CN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cc1N	InChI=1S/C16H16BrN5/c1-22(2)15-8-14-12(7-13(15)18)16(20-9-19-14)21-11-5-3-4-10(17)6-11/h3-9H,18H2,1-2H3,(H,19,20,21)	LVYWXEWYKYOVOX-UHFFFAOYSA-N	3545	CHEMBL96489::4-N-(3-bromophenyl)-7-N,7-N-dimethylquinazoline-4,6,7-triamine::PD153035 Analog::PD153035 Analog 45	Epidermal growth factor receptor	Homo sapiens		 159							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3545&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328211	8033269		CHEMBL96489					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5308	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N	InChI=1S/C15H13BrN4O/c1-21-14-7-13-11(6-12(14)17)15(19-8-18-13)20-10-4-2-3-9(16)5-10/h2-8H,17H2,1H3,(H,18,19,20)	VQTRWXQSANIXPR-UHFFFAOYSA-N	3546	CHEMBL96780::4-N-(3-bromophenyl)-7-methoxyquinazoline-4,6-diamine::PD153035 Analog 46	Epidermal growth factor receptor	Homo sapiens		 3.8							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3546&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328212	8033270		CHEMBL96780					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5309	Nc1cc2c(Nc3cccc(Br)c3)ncnc2cc1Cl	InChI=1S/C14H10BrClN4/c15-8-2-1-3-9(4-8)20-14-10-5-12(17)11(16)6-13(10)18-7-19-14/h1-7H,17H2,(H,18,19,20)	DXPXPVHLPOANFF-UHFFFAOYSA-N	3547	4-N-(3-bromophenyl)-7-chloroquinazoline-4,6-diamine::CHEMBL63469::PD153035 Analog 47	Epidermal growth factor receptor	Homo sapiens		 6.5							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3547&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328213	8033271		CHEMBL63469					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5310	Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+]([O-])=O	InChI=1S/C14H10BrN5O2/c15-8-2-1-3-9(4-8)19-14-10-5-13(20(21)22)11(16)6-12(10)17-7-18-14/h1-7H,16H2,(H,17,18,19)	KLWXDJHZDQENNS-UHFFFAOYSA-N	3548	4-N-(3-bromophenyl)-6-nitroquinazoline-4,7-diamine::PD153035 Analog::CHEMBL93545::PD153035 Analog 48	Epidermal growth factor receptor	Homo sapiens		 53							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3548	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3548&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328214	8033272		CHEMBL93545					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5311	CNc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+]([O-])=O	InChI=1S/C15H12BrN5O2/c1-17-13-7-12-11(6-14(13)21(22)23)15(19-8-18-12)20-10-4-2-3-9(16)5-10/h2-8,17H,1H3,(H,18,19,20)	SIBSADYFORJTDQ-UHFFFAOYSA-N	3549	PD153035 Analog::CHEMBL92936::4-N-(3-bromophenyl)-7-N-methyl-6-nitroquinazoline-4,7-diamine::PD153035 Analog 49	Epidermal growth factor receptor	Homo sapiens		 68							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3549	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3549&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328215	8033273		CHEMBL92936					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5312	CN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+]([O-])=O	InChI=1S/C16H14BrN5O2/c1-21(2)14-8-13-12(7-15(14)22(23)24)16(19-9-18-13)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	GOUUCLJKCPCYMJ-UHFFFAOYSA-N	3550	4-N-(3-bromophenyl)-7-N,7-N-dimethyl-6-nitroquinazoline-4,7-diamine::4-[(3-Bromophenyl)amino]-7-(dimethylamino)-6-nitroquinazoline::PD153035 Analog::CHEMBL93544::PD153035 Analog 50	Epidermal growth factor receptor	Homo sapiens		 2000							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3550	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3550&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328216	8033274		CHEMBL93544					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5313	CC(=O)Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+]([O-])=O	InChI=1S/C16H12BrN5O3/c1-9(23)20-14-7-13-12(6-15(14)22(24)25)16(19-8-18-13)21-11-4-2-3-10(17)5-11/h2-8H,1H3,(H,20,23)(H,18,19,21)	DZUKQELTOOTLPR-UHFFFAOYSA-N	3551	N-{4-[(3-bromophenyl)amino]-6-nitroquinazolin-7-yl}acetamide::CHEMBL93734::PD153035 Analog 51	Epidermal growth factor receptor	Homo sapiens		 28							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3551&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328217	8033275		CHEMBL93734					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5314	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+]([O-])=O	InChI=1S/C15H11BrN4O3/c1-23-14-7-12-11(6-13(14)20(21)22)15(18-8-17-12)19-10-4-2-3-9(16)5-10/h2-8H,1H3,(H,17,18,19)	CZBTZBBBQGIOGA-UHFFFAOYSA-N	3552	CHEMBL65038::N-(3-bromophenyl)-7-methoxy-6-nitroquinazolin-4-amine::PD153035 Analog 52	Epidermal growth factor receptor	Homo sapiens		 15							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3552&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328218	8033276		CHEMBL65038					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5315	[O-][N+](=O)c1cc2c(Nc3cccc(Br)c3)ncnc2cc1Cl	InChI=1S/C14H8BrClN4O2/c15-8-2-1-3-9(4-8)19-14-10-5-13(20(21)22)11(16)6-12(10)17-7-18-14/h1-7H,(H,17,18,19)	DKKLUAKZWKFXMH-UHFFFAOYSA-N	3553	CHEMBL66409::PD153035 Analog::4-[(3-Bromophenyl)amino]-7-chloro-6-nitroquinazoline::N-(3-bromophenyl)-7-chloro-6-nitroquinazolin-4-amine::PD153035 Analog 53	Epidermal growth factor receptor	Homo sapiens		 25							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3553&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328219	8033277		CHEMBL66409					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5316	Brc1cccc(Nc2ncnc3cc4OCOc4cc23)c1	InChI=1S/C15H10BrN3O2/c16-9-2-1-3-10(4-9)19-15-11-5-13-14(21-8-20-13)6-12(11)17-7-18-15/h1-7H,8H2,(H,17,18,19)	OLQRGQFUIYIRSU-UHFFFAOYSA-N	3554	N-(3-bromophenyl)-2H-[1,3]dioxolo[4,5-g]quinazolin-8-amine::CHEMBL93051::PD153035 Analog 54	Epidermal growth factor receptor	Homo sapiens		 15							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3554	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3554&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328220	8033278		CHEMBL93051					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5317	Oc1cc2ncnc(Nc3cccc(Br)c3)c2cc1O	InChI=1S/C14H10BrN3O2/c15-8-2-1-3-9(4-8)18-14-10-5-12(19)13(20)6-11(10)16-7-17-14/h1-7,19-20H,(H,16,17,18)	CZMCXMIIVHUIPE-UHFFFAOYSA-N	3302	4-[(3-bromophenyl)amino]quinazoline-6,7-diol::44 (3-Bromophenyl)amino]-6,7-dihydroxyquinazoline::CHEMBL93032::4-Anilinoquinazoline deriv. 53	Epidermal growth factor receptor	Homo sapiens		 0.17							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3302	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3302&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328050	8033044		CHEMBL93032					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5318	CCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCC	InChI=1S/C18H18BrN3O2/c1-3-23-16-9-14-15(10-17(16)24-4-2)20-11-21-18(14)22-13-7-5-6-12(19)8-13/h5-11H,3-4H2,1-2H3,(H,20,21,22)	YXOXHAUUTIOBDA-UHFFFAOYSA-N	3556	PD153035 Analog::4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline::CHEMBL1204199::N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine::CHEMBL35820::PD153035 Analog 56	Epidermal growth factor receptor	Homo sapiens		 0.006							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3556	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3556&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2857	8033279		CHEMBL35820CHEMBL1204199					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5319	CCCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC	InChI=1S/C20H22BrN3O2/c1-3-8-25-18-11-16-17(12-19(18)26-9-4-2)22-13-23-20(16)24-15-7-5-6-14(21)10-15/h5-7,10-13H,3-4,8-9H2,1-2H3,(H,22,23,24)	ZBOJKFDQWQBBHE-UHFFFAOYSA-N	3557	N-(3-bromophenyl)-6,7-dipropoxyquinazolin-4-amine::CHEMBL418967::PD153035 Analog 57	Epidermal growth factor receptor	Homo sapiens		 0.17							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3557&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328221	8033280		CHEMBL418967					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5320	CCCCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCCC	InChI=1S/C22H26BrN3O2/c1-3-5-10-27-20-13-18-19(14-21(20)28-11-6-4-2)24-15-25-22(18)26-17-9-7-8-16(23)12-17/h7-9,12-15H,3-6,10-11H2,1-2H3,(H,24,25,26)	LTADRFUOHQNUCZ-UHFFFAOYSA-N	3558	N-(3-bromophenyl)-6,7-dibutoxyquinazolin-4-amine::CHEMBL318736::PD153035 Analog 58	Epidermal growth factor receptor	Homo sapiens		 105							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3558	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3558&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328222	8033281		CHEMBL318736					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5321	COc1ccc2ncnc(Nc3cccc(Br)c3)c2c1OC	InChI=1S/C16H14BrN3O2/c1-21-13-7-6-12-14(15(13)22-2)16(19-9-18-12)20-11-5-3-4-10(17)8-11/h3-9H,1-2H3,(H,18,19,20)	YNRSJGOUWDDUMY-UHFFFAOYSA-N	3559	CHEMBL96627::N-(3-bromophenyl)-5,6-dimethoxyquinazolin-4-amine::PD153035 Analog 59	Epidermal growth factor receptor	Homo sapiens		 1367							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3559	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3559&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328223	8033282		CHEMBL96627					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5322	COc1ccc2c(Nc3cccc(Br)c3)ncnc2c1OC	InChI=1S/C16H14BrN3O2/c1-21-13-7-6-12-14(15(13)22-2)18-9-19-16(12)20-11-5-3-4-10(17)8-11/h3-9H,1-2H3,(H,18,19,20)	VEKZVINYTYXCAI-UHFFFAOYSA-N	3560	CHEMBL93346::N-(3-bromophenyl)-7,8-dimethoxyquinazolin-4-amine::PD153035 Analog 60	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3560	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3560&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328224	8033283		CHEMBL93346					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5323	COc1cc2nc(C)nc(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C17H16BrN3O2/c1-10-19-14-9-16(23-3)15(22-2)8-13(14)17(20-10)21-12-6-4-5-11(18)7-12/h4-9H,1-3H3,(H,19,20,21)	YDJAVBPPDOYWGD-UHFFFAOYSA-N	3561	N-(3-bromophenyl)-6,7-dimethoxy-2-methylquinazolin-4-amine::4-[(3-Bromophenyl)amino]-6,7-dimethoxy-2-methylquinazoline Hydrochloride::PD153035 Analog::CHEMBL294769::PD153035 Analog 61	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3561	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3561&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328225	8033284		CHEMBL294769					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5324	COc1cc2nc(N)nc(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C16H15BrN4O2/c1-22-13-7-11-12(8-14(13)23-2)20-16(18)21-15(11)19-10-5-3-4-9(17)6-10/h3-8H,1-2H3,(H3,18,19,20,21)	WYYHXJFKSMRPCR-UHFFFAOYSA-N	3562	PD153035 Analog::4-N-(3-bromophenyl)-6,7-dimethoxyquinazoline-2,4-diamine::2-Amino-4-[(3-bromophenyl)amino]-6,7-dimethoxyquinazoline Trihydrochloride::CHEMBL93295::PD153035 Analog 62	Epidermal growth factor receptor	Homo sapiens		 463							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3562	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3562&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328226	8033285		CHEMBL93295					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5325	COc1cc2ncnc(N(C)c3cccc(Br)c3)c2cc1OC	InChI=1S/C17H16BrN3O2/c1-21(12-6-4-5-11(18)7-12)17-13-8-15(22-2)16(23-3)9-14(13)19-10-20-17/h4-10H,1-3H3	IPWGDOZPSOZFOD-UHFFFAOYSA-N	3563	N-(3-bromophenyl)-6,7-dimethoxy-N-methylquinazolin-4-amine::CHEMBL447230::PD153035 Analog 63	Epidermal growth factor receptor	Homo sapiens		 152							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3563	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3563&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328227	8033286		CHEMBL447230					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5326	COc1cc2ncnc(Nc3cccc(Br)c3)c2c(OC)c1OC	InChI=1S/C17H16BrN3O3/c1-22-13-8-12-14(16(24-3)15(13)23-2)17(20-9-19-12)21-11-6-4-5-10(18)7-11/h4-9H,1-3H3,(H,19,20,21)	MMRJGOKRGZAQNE-UHFFFAOYSA-N	3564	4-[(3-Bromophenyl)amino]-5,6,7-trimethoxyquinazoline::PD153035 Analog::N-(3-bromophenyl)-5,6,7-trimethoxyquinazolin-4-amine::CHEMBL317925::PD153035 Analog 64	Epidermal growth factor receptor	Homo sapiens		 0.67							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3564	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3564&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328228	8033287		CHEMBL317925					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5327	COc1cc2c(Nc3cccc(Br)c3)ncnc2c(OC)c1OC	InChI=1S/C17H16BrN3O3/c1-22-13-8-12-14(16(24-3)15(13)23-2)19-9-20-17(12)21-11-6-4-5-10(18)7-11/h4-9H,1-3H3,(H,19,20,21)	DKGDRWNQVLEBEV-UHFFFAOYSA-N	3565	CHEMBL431811::N-(3-bromophenyl)-6,7,8-trimethoxyquinazolin-4-amine::PD153035 Analog 65	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3565	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3565&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328229	8033288		CHEMBL431811					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5328	COc1cc2ncnc(Nc3ccccc3Br)c2cc1OC	InChI=1S/C16H14BrN3O2/c1-21-14-7-10-13(8-15(14)22-2)18-9-19-16(10)20-12-6-4-3-5-11(12)17/h3-9H,1-2H3,(H,18,19,20)	WNZXENIFRJQCEE-UHFFFAOYSA-N	3566	CHEMBL92174::N-(2-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035 Analog 66	Epidermal growth factor receptor	Homo sapiens		 128							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3566&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328230	8033289		CHEMBL92174					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5329	COc1cc2ncnc(Nc3ccc(Br)cc3)c2cc1OC	InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-10(17)4-6-11/h3-9H,1-2H3,(H,18,19,20)	MCNVTWIIWNZMGB-UHFFFAOYSA-N	3567	CHEMBL328106::N-(4-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035 Analog 67	Epidermal growth factor receptor	Homo sapiens		 0.96							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3567	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3567&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1474852	8033290		CHEMBL328106					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5330	COc1cc2ncnc(Nc3ccc(Br)c(Br)c3)c2cc1OC	InChI=1S/C16H13Br2N3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-9-3-4-11(17)12(18)5-9/h3-8H,1-2H3,(H,19,20,21)	RCDYQKFTBRQJIS-UHFFFAOYSA-N	3568	N-(3,4-dibromophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL327307::PD153035 Analog 68	Epidermal growth factor receptor	Homo sapiens		 0.072							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3568	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3568&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328231	8033291		CHEMBL327307					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5331	COc1cc2ncnc(Nc3cc(Br)cc(Br)c3)c2cc1OC	InChI=1S/C16H13Br2N3O2/c1-22-14-6-12-13(7-15(14)23-2)19-8-20-16(12)21-11-4-9(17)3-10(18)5-11/h3-8H,1-2H3,(H,19,20,21)	HAHWLTAMVXUGEZ-UHFFFAOYSA-N	3569	N-(3,5-dibromophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL92709::PD153035 Analog 69	Epidermal growth factor receptor	Homo sapiens		 113							Curated from the literature by BindingDB	10.1021/jm9503613	10.7270/Q25T3HPR	8568816	aid1795540		Bridges, AJ; Zhou, HR; Cody, DR; Rewcastle, GW; McMichael, A; Showalter, HH; Fry, DW; Kraker, AJ; Denny, WA	1/5/1996	3/8/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3569&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328232	8033292		CHEMBL92709					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5332	Brc1cccc(Nc2ncnc3cc4nc[nH]c4cc23)c1	InChI=1S/C15H10BrN5/c16-9-2-1-3-10(4-9)21-15-11-5-13-14(19-7-18-13)6-12(11)17-8-20-15/h1-8H,(H,18,19)(H,17,20,21)	BZHDPIVTQKXAQQ-UHFFFAOYSA-N	3570	N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amine::CHEMBL66031::Anilinopyrimidine deriv. 7a::8-[(3-Bromophenyl)amino]-1H-imidazo[4,5-g]quinazoline::Imidazoquinazoline deriv. 8	Epidermal growth factor receptor	Homo sapiens		 0.008					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3570&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2428	8033293		CHEMBL66031					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5333	Cc1nc2cc3ncnc(Nc4cccc(Br)c4)c3cc2[nH]1	InChI=1S/C16H12BrN5/c1-9-20-14-6-12-13(7-15(14)21-9)18-8-19-16(12)22-11-4-2-3-10(17)5-11/h2-8H,1H3,(H,20,21)(H,18,19,22)	KCNKSDOEWSRVHK-UHFFFAOYSA-N	3571	N-(3-bromophenyl)-2-methyl-1H-imidazo[4,5-g]quinazolin-8-amine::8-[(3-Bromophenyl)amino]-2-methyl-1H-imidazo[4,5-g]-quinazoline::Imidazoquinazoline deriv. 9	Epidermal growth factor receptor	Homo sapiens		 0.29					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3571	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3571&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328233	8033294							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5334	Cn1cnc2cc3ncnc(Nc4cccc(Br)c4)c3cc12	InChI=1S/C16H12BrN5/c1-22-9-20-14-7-13-12(6-15(14)22)16(19-8-18-13)21-11-4-2-3-10(17)5-11/h2-9H,1H3,(H,18,19,21)	LQIKOEJHMCCOSP-UHFFFAOYSA-N	3572	N-(3-bromophenyl)-1-methyl-1H-imidazo[4,5-g]quinazolin-8-amine::8-[(3-Bromophenyl)amino]-1-methyl-1H-imidazo[4,5-g]-quinazoline::Imidazoquinazoline deriv. 10	Epidermal growth factor receptor	Homo sapiens		 0.01					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3572&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328234	8033295							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5335	CN(C)CCn1cnc2cc3ncnc(Nc4cccc(Br)c4)c3cc12	InChI=1S/C19H19BrN6/c1-25(2)6-7-26-12-23-17-10-16-15(9-18(17)26)19(22-11-21-16)24-14-5-3-4-13(20)8-14/h3-5,8-12H,6-7H2,1-2H3,(H,21,22,24)	FIBRZYOROMWVIM-UHFFFAOYSA-N	3573	N-(3-bromophenyl)-1-[2-(dimethylamino)ethyl]-1H-imidazo[4,5-g]quinazolin-8-amine::8-[(3-Bromophenyl)amino]-1-[2-(dimethylamino)ethyl]-1H-imidazo[4,5-g]quinazoline::Imidazoquinazoline deriv. 11	Epidermal growth factor receptor	Homo sapiens		 1.32					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3573	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3573&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328235	8033296							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5336	Cn1cnc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C16H12BrN5/c1-22-9-20-14-6-12-13(7-15(14)22)18-8-19-16(12)21-11-4-2-3-10(17)5-11/h2-9H,1H3,(H,18,19,21)	YAMAGACQNDAKFB-UHFFFAOYSA-N	3574	8-[(3-Bromophenyl)amino]-3-methyl-3H-imidazo[4,5-g]-quinazoline::N-(3-bromophenyl)-3-methyl-3H-imidazo[4,5-g]quinazolin-8-amine::Imidazoquinazoline deriv. 12	Epidermal growth factor receptor	Homo sapiens		 0.025					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3574&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2427	8033297							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5337	CN(C)CCn1cnc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C19H19BrN6/c1-25(2)6-7-26-12-23-17-9-15-16(10-18(17)26)21-11-22-19(15)24-14-5-3-4-13(20)8-14/h3-5,8-12H,6-7H2,1-2H3,(H,21,22,24)	CAHQBZBYEQNNHC-UHFFFAOYSA-N	3575	N-(3-bromophenyl)-3-[2-(dimethylamino)ethyl]-3H-imidazo[4,5-g]quinazolin-8-amine::8-[(3-Bromophenyl)amino]-3-[2-(dimethylamino)ethyl]-3H-imidazo[4,5-g]quinazoline::Imidazoquinazoline deriv. 13	Epidermal growth factor receptor	Homo sapiens		 22					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3575	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3575&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328236	8033298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5338	CN(C)CCn1cnc2c(Cl)c3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C19H18BrClN6/c1-26(2)6-7-27-11-24-18-15(27)9-14-16(17(18)21)19(23-10-22-14)25-13-5-3-4-12(20)8-13/h3-5,8-11H,6-7H2,1-2H3,(H,22,23,25)	ZPJWMBTXUODZPM-UHFFFAOYSA-N	3576	8-[(3-Bromophenyl)amino]-9-chloro-3-[2-(dimethylamino)ethyl]-3H-imidazo[4,5-g]quinazoline::N-(3-bromophenyl)-9-chloro-3-[2-(dimethylamino)ethyl]-3H-imidazo[4,5-g]quinazolin-8-amine::Imidazoquinazoline deriv. 14	Epidermal growth factor receptor	Homo sapiens		 203					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3576&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328237	8033299							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5339	Brc1cccc(Nc2ncnc3ccc4[nH]cnc4c23)c1	InChI=1S/C15H10BrN5/c16-9-2-1-3-10(6-9)21-15-13-11(17-8-20-15)4-5-12-14(13)19-7-18-12/h1-8H,(H,18,19)(H,17,20,21)	ZCTBHAZSEIICRJ-UHFFFAOYSA-N	3577	9-[(3-Bromophenyl)amino]-1H-imidazo[4,5-f]quinazoline::N-(3-bromophenyl)-3,5,10,12-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,7,10,12-hexaen-13-amine::Anilinopyrimidine deriv. 8a::Imidazoquinazoline deriv. 15	Epidermal growth factor receptor	Homo sapiens		 29					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3577&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328238	8033300							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5340	Brc1cccc(Nc2ncnc3c4nc[nH]c4ccc23)c1	InChI=1S/C15H10BrN5/c16-9-2-1-3-10(6-9)21-15-11-4-5-12-14(19-7-17-12)13(11)18-8-20-15/h1-8H,(H,17,19)(H,18,20,21)	NIYBTTXLFLIXIE-UHFFFAOYSA-N	3578	6-[(3-Bromophenyl)amino]-1H-imidazo[4,5-h]quinazoline::N-(3-bromophenyl)-3,5,11,13-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,7,10,12-hexaen-10-amine::Anilinopyrimidine deriv. 9::Imidazoquinazoline deriv. 16	Epidermal growth factor receptor	Homo sapiens		 272					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3578&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328239	8033301							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5341	Brc1cccc(Nc2ncnc3cc4nn[nH]c4cc23)c1	InChI=1S/C14H9BrN6/c15-8-2-1-3-9(4-8)18-14-10-5-12-13(20-21-19-12)6-11(10)16-7-17-14/h1-7H,(H,16,17,18)(H,19,20,21)	VICIYGAOMIRRLW-UHFFFAOYSA-N	3579	8-[(3-Bromophenyl)amino]-1H-1,2,3-triazolo[4,5-g]-quinazoline::N-(3-bromophenyl)-1H-[1,2,3]triazolo[4,5-g]quinazolin-8-amine::Triazoloquinazoline deriv. 17	Epidermal growth factor receptor	Homo sapiens		 4.1					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3579&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			6419347	8033302							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5342	Brc1cccc(Nc2ncnc3cc4ncsc4cc23)c1	InChI=1S/C15H9BrN4S/c16-9-2-1-3-10(4-9)20-15-11-5-14-13(19-8-21-14)6-12(11)17-7-18-15/h1-8H,(H,17,18,20)	IRGSEHJOWJXKPV-UHFFFAOYSA-N	3580	N-(3-bromophenyl)quinazolino[7,6-d][1,3]thiazol-8-amine::8-[(3-Bromophenyl)amino]thiazolo[5,4-g]quinazoline::Thiazoloquinazoline deriv. 18	Epidermal growth factor receptor	Homo sapiens		 44					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3580	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3580&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328240	8033303							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5343	Brc1cccc(Nc2ncnc3cc4cn[nH]c4cc23)c1	InChI=1S/C15H10BrN5/c16-10-2-1-3-11(5-10)20-15-12-6-13-9(7-19-21-13)4-14(12)17-8-18-15/h1-8H,(H,19,21)(H,17,18,20)	PKYIIOKOAUBHMM-UHFFFAOYSA-N	3581	N-(3-bromophenyl)-1H-pyrazolo[3,4-g]quinazolin-8-amine::8-[(3-Bromophenyl)amino]-1H-pyrazolo[3,4-g]quinazoline::Pyrazoloquinazoline deriv. 19	Epidermal growth factor receptor	Homo sapiens		 0.34					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3581	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3581&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328241	8033304							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5344	Brc1cccc(Nc2ncnc3cc4[nH]ncc4cc23)c1	InChI=1S/C15H10BrN5/c16-10-2-1-3-11(5-10)20-15-12-4-9-7-19-21-13(9)6-14(12)17-8-18-15/h1-8H,(H,19,21)(H,17,18,20)	ORCWMSOZENFEDR-UHFFFAOYSA-N	3582	N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-amine::Anilinopyrimidine deriv. 7c::Pyrazoloquinazoline deriv. 2a::5-[(3-Bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazoline::Pyrazoloquinazoline deriv. 20	Epidermal growth factor receptor	Homo sapiens		 0.44					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3582&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328242	8033305							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5345	Brc1cccc(Nc2ncnc3cc4[nH]ccc4cc23)c1	InChI=1S/C16H11BrN4/c17-11-2-1-3-12(7-11)21-16-13-6-10-4-5-18-14(10)8-15(13)19-9-20-16/h1-9,18H,(H,19,20,21)	BBFWQWIFLDQYQQ-UHFFFAOYSA-N	3583	Pyrroloquinazoline deriv. 3a::Anilinopyrimidine deriv. 7b::5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazoline::N-(3-bromophenyl)-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 21	Epidermal growth factor receptor	Homo sapiens		 0.44					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3583&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328243	8033306							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5346	Brc1cccc(Nc2ncnc3ccc4cc[nH]c4c23)c1	InChI=1S/C16H11BrN4/c17-11-2-1-3-12(8-11)21-16-14-13(19-9-20-16)5-4-10-6-7-18-15(10)14/h1-9,18H,(H,19,20,21)	DRORNTZBMUKMSZ-UHFFFAOYSA-N	3584	N-(3-bromophenyl)-3,10,12-triazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,7,10,12-hexaen-13-amine::Anilinopyrimidine deriv. 8b::9-[(3-Bromophenyl)amino]-1H-pyrrolo[2,3-f]quinazoline::Pyrroloquinazoline deriv. 22	Epidermal growth factor receptor	Homo sapiens		 1.24					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3584&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328244	8033307							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5347	Brc1cccc(Nc2ncnc3cc4ccccc4cc23)c1	InChI=1S/C18H12BrN3/c19-14-6-3-7-15(10-14)22-18-16-8-12-4-1-2-5-13(12)9-17(16)20-11-21-18/h1-11H,(H,20,21,22)	BUVKJPOCMOXSSQ-UHFFFAOYSA-N	3585	4-[(3-Bromophenyl)amino]benzo[g]quinazoline::N-(3-bromophenyl)benzo[g]quinazolin-4-amine::CHEMBL63786::Benzoquinazoline deriv. 23	Epidermal growth factor receptor	Homo sapiens		 0.003					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3585	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3585&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328245	8033308		CHEMBL63786					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5348	Brc1cccc(Nc2ncnc3cc4nccnc4cc23)c1	InChI=1S/C16H10BrN5/c17-10-2-1-3-11(6-10)22-16-12-7-14-15(19-5-4-18-14)8-13(12)20-9-21-16/h1-9H,(H,20,21,22)	ZZAZKOOJVIBTOP-UHFFFAOYSA-N	3586	N-(3-bromophenyl)pyrazino[2,3-g]quinazolin-4-amine::4-[(3-Bromophenyl)amino]pyrazino[2,3-g]quinazoline::Pyrazinoquinazoline deriv. 24	Epidermal growth factor receptor	Homo sapiens		 1.7					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm950692f	10.7270/Q2222RZB	8632415	aid1795546		Rewcastle, GW; Palmer, BD; Bridges, AJ; Showalter, HD; Sun, L; Nelson, J; McMichael, A; Kraker, AJ; Fry, DW; Denny, WA	2/16/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3586	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3586&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328246	8033309							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5349	C(Nc1ncnc2ccncc12)c1ccccc1	InChI=1S/C14H12N4/c1-2-4-11(5-3-1)8-16-14-12-9-15-7-6-13(12)17-10-18-14/h1-7,9-10H,8H2,(H,16,17,18)	XZPCYVKAGQFORE-UHFFFAOYSA-N	3587	CHEMBL54784::4-[(Phenylmethyl)amino]-pyrido[4,3-d]pyrimidine::N-benzylpyrido[4,3-d]pyrimidin-4-amine::Pyrido[4,3-d]pyrimidine 4a	Epidermal growth factor receptor	Homo sapiens		 1460					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3587&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328247	8033310		CHEMBL54784					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5350	Nc1cc2ncnc(NCc3ccccc3)c2cn1	InChI=1S/C14H13N5/c15-13-6-12-11(8-16-13)14(19-9-18-12)17-7-10-4-2-1-3-5-10/h1-6,8-9H,7H2,(H2,15,16)(H,17,18,19)	JBRBEQRTMVYDCU-UHFFFAOYSA-N	3331	4-N-benzylpyrido[4,3-d]pyrimidine-4,7-diamine::CHEMBL300083::7-Amino-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidine::7-Aminopyrido[4,3-d]pyrimidine 8a	Epidermal growth factor receptor	Homo sapiens		 578					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3331	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3331&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328077	8033073		CHEMBL300083					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5351	CC(=O)Nc1cc2ncnc(NCc3ccccc3)c2cn1	InChI=1S/C16H15N5O/c1-11(22)21-15-7-14-13(9-17-15)16(20-10-19-14)18-8-12-5-3-2-4-6-12/h2-7,9-10H,8H2,1H3,(H,17,21,22)(H,18,19,20)	PVCHTGBTKFGXJK-UHFFFAOYSA-N	3589	CHEMBL53404::N-[4-(benzylamino)pyrido[4,3-d]pyrimidin-7-yl]acetamide::7-Acetamido-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidine::Pyrido[4,3-d]pyrimidine 4c	Epidermal growth factor receptor	Homo sapiens		 100					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3589&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328248	8033311		CHEMBL53404					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5352	Brc1cccc(Nc2ncnc3ccncc23)c1	InChI=1S/C13H9BrN4/c14-9-2-1-3-10(6-9)18-13-11-7-15-5-4-12(11)16-8-17-13/h1-8H,(H,16,17,18)	KXQSONXECJTULQ-UHFFFAOYSA-N	3590	CHEMBL52665::4-[(3-Bromophenyl)-amino]pyrido[4,3-d]pyrimidine::N-(3-bromophenyl)pyrido[4,3-d]pyrimidin-4-amine::Pyrido[4,3-d]pyrimidine 5a	Epidermal growth factor receptor	Homo sapiens		 35					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3590	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3590&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328249	8033312		CHEMBL52665					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5353	Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	SFUYILVZGXHCDG-UHFFFAOYSA-N	3309	4-N-(3-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidine::CHEMBL52076::7-Aminopyrido[4,3-d]pyrimidine 7f	Epidermal growth factor receptor	Homo sapiens		 10					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			382059	8033051		CHEMBL52076					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5354	CC(=O)Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C15H12BrN5O/c1-9(22)20-14-6-13-12(7-17-14)15(19-8-18-13)21-11-4-2-3-10(16)5-11/h2-8H,1H3,(H,17,20,22)(H,18,19,21)	KKLFLZHHIPZMHQ-UHFFFAOYSA-N	3592	7-Acetamido-4-[(3-bromophenyl)amino]pyrido[4,3-d]-pyrimidine::CHEMBL52418::N-{4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}acetamide::Pyrido[4,3-d]pyrimidine 5c	Epidermal growth factor receptor	Homo sapiens		 29					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3592	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3592&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328250	8033313		CHEMBL52418					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5355	Fc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H,17,18,19)	ZSEDCGVJIAHLRN-UHFFFAOYSA-N	3593	4-[(3-Bromophenyl)amino]-7-fluoropyrido[4,3-d]pyrimidine::CHEMBL51707::N-(3-bromophenyl)-7-fluoropyrido[4,3-d]pyrimidin-4-amine::Pyrido[4,3-d]pyrimidine 5e	Epidermal growth factor receptor	Homo sapiens		 13					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3593	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3593&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328251	8033314		CHEMBL51707					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5356	CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C14H12BrN5/c1-16-13-6-12-11(7-17-13)14(19-8-18-12)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)	SOVBDLAXFPZPCR-UHFFFAOYSA-N	3594	4-N-(3-bromophenyl)-7-N-methylpyrido[4,3-d]pyrimidine-4,7-diamine::CHEMBL54400::4-[(3-Bromophenyl)amino]-7-(methylamino)pyrido[4,3-d]pyrimidine::Pyrido[4,3-d]pyrimidine 5f	Epidermal growth factor receptor	Homo sapiens		 0.13					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3594&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328252	8033315		CHEMBL54400					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5357	CN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C15H14BrN5/c1-21(2)14-7-13-12(8-17-14)15(19-9-18-13)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)	FKFFXIBNVYSRTJ-UHFFFAOYSA-N	3595	4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-(dimethylamino)pyrido-[4,3-d]pyrimidine::CHEMBL53428::Pyrido[4,3-d]pyrimidine 5g	Epidermal growth factor receptor	Homo sapiens		 0.091					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3595	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3595&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328253	8033316		CHEMBL53428					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5358	COc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C14H11BrN4O/c1-20-13-6-12-11(7-16-13)14(18-8-17-12)19-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,17,18,19)	VBKYHRRXRGHYHL-UHFFFAOYSA-N	3596	N-(3-bromophenyl)-7-methoxypyrido[4,3-d]pyrimidin-4-amine::CHEMBL53375::4-[(3-Bromophenyl)amino]-7-methoxypyrido[4,3-d]pyrimidine::Pyrido[4,3-d]pyrimidine 5h	Epidermal growth factor receptor	Homo sapiens		 39					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3596&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328254	8033317		CHEMBL53375					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5359	CNc1cc2ncn(C)\c(=N/c3cccc(Br)c3)c2cn1	InChI=1S/C15H14BrN5/c1-17-14-7-13-12(8-18-14)15(21(2)9-19-13)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,17,18)	KGPJHDOZKFVFLW-UHFFFAOYSA-N	3597	(4Z)-4-[(3-bromophenyl)imino]-N,3-dimethyl-3H,4H-pyrido[4,3-d]pyrimidin-7-amine::N4-(3-bromophenyl)-3-methyl-7-(methylamino)-pyrido[4,3-d]pyrimidin-4(3H)-imine::Pyrido[4,3-d]pyrimidine 12	Epidermal growth factor receptor	Homo sapiens		 3.1					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3597&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328255	8033318							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5360	C(Nc1ncnc2cnccc12)c1ccccc1	InChI=1S/C14H12N4/c1-2-4-11(5-3-1)8-16-14-12-6-7-15-9-13(12)17-10-18-14/h1-7,9-10H,8H2,(H,16,17,18)	SCPGISLJHLHVLE-UHFFFAOYSA-N	3598	N-benzylpyrido[3,4-d]pyrimidin-4-amine::4-[(Phenylmethyl)amino]-pyrido[3,4-d]pyrimidine::CHEMBL51320::Pyrido[3,4-d]pyrimidine 6a	Epidermal growth factor receptor	Homo sapiens		 2030					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3598	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3598&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328256	8033319		CHEMBL51320					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5361	Brc1cccc(Nc2ncnc3cnccc23)c1	InChI=1S/C13H9BrN4/c14-9-2-1-3-10(6-9)18-13-11-4-5-15-7-12(11)16-8-17-13/h1-8H,(H,16,17,18)	BWXVBEQVOBGQHC-UHFFFAOYSA-N	3599	CHEMBL51265::N-(3-bromophenyl)pyrido[3,4-d]pyrimidin-4-amine::4-[(3-Bromophenyl)-amino]pyrido[3,4-d]pyrimidine::Pyrido[3,4-d]pyrimidine 7a	Epidermal growth factor receptor	Homo sapiens		 51					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3599	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3599&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328257	8033320		CHEMBL51265					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5362	Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	TWTYLCVLKNHZDT-UHFFFAOYSA-N	3600	4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine::CHEMBL51853::Pyrido[3,4-d]pyrimidine 7b	Epidermal growth factor receptor	Homo sapiens		 0.13					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3600&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328258	8033321		CHEMBL51853					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5363	Clc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C13H8BrClN4/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H,17,18,19)	APXDAYLGZSXVDB-UHFFFAOYSA-N	3601	CHEMBL296377::N-(3-bromophenyl)-6-chloropyrido[3,4-d]pyrimidin-4-amine::4-[(3-Bromophenyl)amino]-6-chloropyrido[3,4-d]pyrimidine::Pyrido[3,4-d]pyrimidine 7d	Epidermal growth factor receptor	Homo sapiens		 40					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3601	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3601&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328259	8033322		CHEMBL296377					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5364	Fc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H,17,18,19)	KRRHOFYUUHSVEQ-UHFFFAOYSA-N	3602	4-[(3-Bromophenyl)amino]-6-fluoropyrido[3,4-d]pyrimidine::CHEMBL53121::N-(3-bromophenyl)-6-fluoropyrido[3,4-d]pyrimidin-4-amine::Pyrido[3,4-d]pyrimidine 7e	Epidermal growth factor receptor	Homo sapiens		 124					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3602	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3602&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328260	8033323		CHEMBL53121					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5365	CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)	KFHMLBXBRCITHF-UHFFFAOYSA-N	3603	4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine::CHEMBL53753::PD158780	Epidermal growth factor receptor	Homo sapiens		 0.008					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3603&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4707	8033324		CHEMBL53753					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5366	CN(C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C15H14BrN5/c1-21(2)14-7-12-13(8-17-14)18-9-19-15(12)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)	QFXMHNZCUIIRHD-UHFFFAOYSA-N	3604	CHEMBL53711::4-[(3-bromophenyl)-amino]-6-(dimethylamino)pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine::Pyrido[3,4-d]pyrimidine 7g	Epidermal growth factor receptor	Homo sapiens		 0.006					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3604&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328261	8033325		CHEMBL53711					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5367	COc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C14H11BrN4O/c1-20-13-6-11-12(7-16-13)17-8-18-14(11)19-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,17,18,19)	ODVAMUDYBBPTAL-UHFFFAOYSA-N	3605	4-[(3-bromophenyl)amino]-6-methoxypyrido[3,4-d]pyrimidine::CHEMBL53062::N-(3-bromophenyl)-6-methoxypyrido[3,4-d]pyrimidin-4-amine::Pyrido[3,4-d]pyrimidine 7h	Epidermal growth factor receptor	Homo sapiens		 2.6							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3605	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3605&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328262	8033326		CHEMBL53062					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5368	COc1ccc(CNc2cc3c(Nc4cccc(Br)c4)ncnc3cn2)cc1	InChI=1S/C21H18BrN5O/c1-28-17-7-5-14(6-8-17)11-23-20-10-18-19(12-24-20)25-13-26-21(18)27-16-4-2-3-15(22)9-16/h2-10,12-13H,11H2,1H3,(H,23,24)(H,25,26,27)	CXLKPXBPOPTFNY-UHFFFAOYSA-N	3606	CHEMBL53299::4-N-(3-bromophenyl)-6-N-[(4-methoxyphenyl)methyl]pyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-bromophenyl)amino]-6-[(4-methoxyphenyl)-methylamino]pyrido[3,4-d]pyrimidine::Pyrido[3,4-d]pyrimidine 7i	Epidermal growth factor receptor	Homo sapiens		 2.3							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3606	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3606&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328263	8033327		CHEMBL53299					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5369	CNc1cc2c(Nc3ccccc3)ncnc2cn1	InChI=1S/C14H13N5/c1-15-13-7-11-12(8-16-13)17-9-18-14(11)19-10-5-3-2-4-6-10/h2-9H,1H3,(H,15,16)(H,17,18,19)	VUQQZAQCQFIXAH-UHFFFAOYSA-N	3607	6-N-methyl-4-N-phenylpyrido[3,4-d]pyrimidine-4,6-diamine::CHEMBL53940::6-(Methylamino)-4-(phenylamino)pyrido[3,4-d]pyrimidine::Pyrido[3,4-d]pyrimidine 13f	Epidermal growth factor receptor	Homo sapiens		 9.0							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3607	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3607&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328264	8033328		CHEMBL53940					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5370	C(Nc1ncnc2ncccc12)c1ccccc1	InChI=1S/C14H12N4/c1-2-5-11(6-3-1)9-16-14-12-7-4-8-15-13(12)17-10-18-14/h1-8,10H,9H2,(H,15,16,17,18)	FVEXQJMRVAZNAH-UHFFFAOYSA-N	3608	CHEMBL54383::N-benzylpyrido[2,3-d]pyrimidin-4-amine::4-[(Phenylmethyl)amino]-pyrido[2,3-d]pyrimidine::Pyrido[2,3-d]pyrimidine 8a	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3608&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328265	8033329		CHEMBL54383					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5371	Brc1cccc(Nc2ncnc3ncccc23)c1	InChI=1S/C13H9BrN4/c14-9-3-1-4-10(7-9)18-13-11-5-2-6-15-12(11)16-8-17-13/h1-8H,(H,15,16,17,18)	DMQAKAYWBRHCDT-UHFFFAOYSA-N	3609	CHEMBL54475::N-(3-bromophenyl)pyrido[2,3-d]pyrimidin-4-amine::4-[(3-bromophenyl)-amino]pyrido[2,3-d]pyrimidine::Pyrido[2,3-d]pyrimidine 9a	Epidermal growth factor receptor	Homo sapiens		 688							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3609	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3609&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328266	8033330		CHEMBL54475					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5372	Nc1ccc2c(Nc3cccc(Br)c3)ncnc2n1	InChI=1S/C13H10BrN5/c14-8-2-1-3-9(6-8)18-12-10-4-5-11(15)19-13(10)17-7-16-12/h1-7H,(H3,15,16,17,18,19)	FHXNETSSNWTSDM-UHFFFAOYSA-N	3610	7-amino-4-[(3-bromophenyl)amino]pyrido[2,3-d]pyrimidine::4-N-(3-bromophenyl)pyrido[2,3-d]pyrimidine-4,7-diamine::CHEMBL54474::Pyrido[2,3-d]pyrimidine 9b	Epidermal growth factor receptor	Homo sapiens		 940							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3610	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3610&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328267	8033331		CHEMBL54474					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5373	Fc1ccc2c(Nc3cccc(Br)c3)ncnc2n1	InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(6-8)18-12-10-4-5-11(15)19-13(10)17-7-16-12/h1-7H,(H,16,17,18,19)	DVVACVMEJKXNQG-UHFFFAOYSA-N	3611	CHEMBL291701::N-(3-bromophenyl)-7-fluoropyrido[2,3-d]pyrimidin-4-amine::4-[(3-Bromophenyl)amino]-7-fluoropyrido[2,3-d]pyrimidine::Pyrido[2,3-d]pyrimidine 9e	Epidermal growth factor receptor	Homo sapiens		 684							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3611	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3611&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328268	8033332		CHEMBL291701					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5374	CNc1ccc2c(Nc3cccc(Br)c3)ncnc2n1	InChI=1S/C14H12BrN5/c1-16-12-6-5-11-13(17-8-18-14(11)20-12)19-10-4-2-3-9(15)7-10/h2-8H,1H3,(H2,16,17,18,19,20)	WMBRHVWLKLLTEE-UHFFFAOYSA-N	3612	CHEMBL298637::4-[(3-bromophenyl)amino]-7-(methylamino)pyrido[2,3-d]pyrimidine::4-N-(3-bromophenyl)-7-N-methylpyrido[2,3-d]pyrimidine-4,7-diamine::Pyrido[2,3-d]pyrimidine 9f	Epidermal growth factor receptor	Homo sapiens		 52							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3612	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3612&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328269	8033333		CHEMBL298637					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5375	CN(C)c1ccc2c(Nc3cccc(Br)c3)ncnc2n1	InChI=1S/C15H14BrN5/c1-21(2)13-7-6-12-14(17-9-18-15(12)20-13)19-11-5-3-4-10(16)8-11/h3-9H,1-2H3,(H,17,18,19,20)	CYDSVLVEOYKRBO-UHFFFAOYSA-N	3613	4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[2,3-d]pyrimidine-4,7-diamine::4-[(3-bromophenyl)amino]-7-(dimethylamino)pyrido[2,3-d]pyrimidine::CHEMBL50245::Pyrido[2,3-d]pyrimidine 9g	Epidermal growth factor receptor	Homo sapiens		 324							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3613&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328270	8033334		CHEMBL50245					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5376	COc1ccc2c(Nc3cccc(Br)c3)ncnc2n1	InChI=1S/C14H11BrN4O/c1-20-12-6-5-11-13(16-8-17-14(11)19-12)18-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,17,18,19)	OQQQTEPDBHVQDX-UHFFFAOYSA-N	3614	CHEMBL301549::4-[(3-bromophenyl)amino]-7-methoxypyrido[2,3-d]pyrimidine::N-(3-bromophenyl)-7-methoxypyrido[2,3-d]pyrimidin-4-amine::Pyrido[2,3-d]pyrimidine 9h	Epidermal growth factor receptor	Homo sapiens		 263							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3614	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3614&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328271	8033335		CHEMBL301549					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5377	C(Nc1ncnc2cccnc12)c1ccccc1	InChI=1S/C14H12N4/c1-2-5-11(6-3-1)9-16-14-13-12(17-10-18-14)7-4-8-15-13/h1-8,10H,9H2,(H,16,17,18)	WALLIFXHVLZYJG-UHFFFAOYSA-N	3615	N-benzylpyrido[3,2-d]pyrimidin-4-amine::4-[(Phenylmethyl)amino]-pyrido[3,2-d]pyrimidine::CHEMBL53552::Pyrido[3,2-d]pyrimidine 10a	Epidermal growth factor receptor	Homo sapiens		 603							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3615	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3615&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328272	8033336		CHEMBL53552					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5378	Brc1cccc(Nc2ncnc3cccnc23)c1	InChI=1S/C13H9BrN4/c14-9-3-1-4-10(7-9)18-13-12-11(16-8-17-13)5-2-6-15-12/h1-8H,(H,16,17,18)	XFTYJIWMIPTWTF-UHFFFAOYSA-N	3616	CHEMBL54805::N-(3-bromophenyl)pyrido[3,2-d]pyrimidin-4-amine::4-[(3-Bromophenyl)-amino]pyrido[3,2-d]pyrimidine::Pyrido[3,2-d]pyrimidine 11a	Epidermal growth factor receptor	Homo sapiens		 34							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3616&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328273	8033337		CHEMBL54805					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5379	Nc1ccc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C13H10BrN5/c14-8-2-1-3-9(6-8)18-13-12-10(16-7-17-13)4-5-11(15)19-12/h1-7H,(H2,15,19)(H,16,17,18)	PWLAEHXFQCNKSK-UHFFFAOYSA-N	3617	6-amino-4-[(3-bromophenyl)amino]-pyrido[3,2-d]pyrimidine::4-N-(3-bromophenyl)pyrido[3,2-d]pyrimidine-4,6-diamine::CHEMBL300217::Pyrido[3,2-d]pyrimidine 11b	Epidermal growth factor receptor	Homo sapiens		 7.6							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3617&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328274	8033338		CHEMBL300217					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5380	Clc1ccc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C13H8BrClN4/c14-8-2-1-3-9(6-8)18-13-12-10(16-7-17-13)4-5-11(15)19-12/h1-7H,(H,16,17,18)	HEOTUKSOHVSEDI-UHFFFAOYSA-N	3618	4-[(3-Bromophenyl)amino]-6-chloropyrido[3,2-d]pyrimidine::CHEMBL291496::N-(3-bromophenyl)-6-chloropyrido[3,2-d]pyrimidin-4-amine::Pyrido[3,2-d]pyrimidine 11d	Epidermal growth factor receptor	Homo sapiens		 18							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3618&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328275	8033339		CHEMBL291496					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5381	Fc1ccc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(6-8)18-13-12-10(16-7-17-13)4-5-11(15)19-12/h1-7H,(H,16,17,18)	IEMOICPYMPGBAD-UHFFFAOYSA-N	3619	4-[(3-bromophenyl)-amino]-6-fluoropyrido[3,2-d]pyrimidine::CHEMBL54788::N-(3-bromophenyl)-6-fluoropyrido[3,2-d]pyrimidin-4-amine::Pyrido[3,2-d]pyrimidine 11e	Epidermal growth factor receptor	Homo sapiens		 44							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3619	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3619&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328276	8033340		CHEMBL54788					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5382	CNc1ccc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C14H12BrN5/c1-16-12-6-5-11-13(20-12)14(18-8-17-11)19-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,20)(H,17,18,19)	MKXXQHSAJJMCBR-UHFFFAOYSA-N	3620	CHEMBL53156::4-N-(3-bromophenyl)-6-N-methylpyrido[3,2-d]pyrimidine-4,6-diamine::4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,2-d]pyrimidine::Pyrido[3,2-d]pyrimidine 11f	Epidermal growth factor receptor	Homo sapiens		 3.1							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3620&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328277	8033341		CHEMBL53156					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5383	CN(C)c1ccc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C15H14BrN5/c1-21(2)13-7-6-12-14(20-13)15(18-9-17-12)19-11-5-3-4-10(16)8-11/h3-9H,1-2H3,(H,17,18,19)	VUFZZYOKJHFSAA-UHFFFAOYSA-N	3621	4-[(3-bromophenyl)amino]-6-(dimethylamino)pyrido[3,2-d]pyrimidine::4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,2-d]pyrimidine-4,6-diamine::CHEMBL53796::Pyrido[3,2-d]pyrimidine 11g	Epidermal growth factor receptor	Homo sapiens		 9.6							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3621	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3621&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328278	8033342		CHEMBL53796					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5384	COc1ccc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C14H11BrN4O/c1-20-12-6-5-11-13(19-12)14(17-8-16-11)18-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,17,18)	ZXEVFSPNUIEQJL-UHFFFAOYSA-N	3622	N-(3-bromophenyl)-6-methoxypyrido[3,2-d]pyrimidin-4-amine::4-[(3-bromophenyl)amino]-6-methoxypyrido[3,2-d]pyrimidine::CHEMBL50519::Pyrido[3,2-d]pyrimidine 11h	Epidermal growth factor receptor	Homo sapiens		 4.3							Curated from the literature by BindingDB	10.1021/jm9508651	10.7270/Q2X928GF	8627606	aid1795547		Rewcastle, GW; Palmer, BD; Thompson, AW; Bridges, AJ; Cody, DR; Zhou, HR; Fry, DW; McMichael, A; Denny, WA	4/26/1996	3/9/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3622&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328279	8033343		CHEMBL50519					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5385	Brc1cccc(Nc2ncnc3cc4[nH]ncc4cc23)c1	InChI=1S/C15H10BrN5/c16-10-2-1-3-11(5-10)20-15-12-4-9-7-19-21-13(9)6-14(12)17-8-18-15/h1-8H,(H,19,21)(H,17,18,20)	ORCWMSOZENFEDR-UHFFFAOYSA-N	3582	N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-amine::Anilinopyrimidine deriv. 7c::Pyrazoloquinazoline deriv. 2a::5-[(3-Bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazoline::Pyrazoloquinazoline deriv. 20	Epidermal growth factor receptor	Homo sapiens		 0.44					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3582&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328242	8033305							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5386	Cn1ncc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C16H12BrN5/c1-22-15-7-14-13(5-10(15)8-20-22)16(19-9-18-14)21-12-4-2-3-11(17)6-12/h2-9H,1H3,(H,18,19,21)	BBWYQCNFQUTQED-UHFFFAOYSA-N	3624	N-(3-bromophenyl)-1-methyl-1H-pyrazolo[4,3-g]quinazolin-5-amine::5-[(3-Bromophenyl)amino]-1-methylpyrazolo[4,3-g]-quinazoline::Pyrazoloquinazoline deriv. 2b	Epidermal growth factor receptor	Homo sapiens		 0.37					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3624	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3624&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328280	8033344							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5387	OCC(O)Cn1ncc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C18H16BrN5O2/c19-12-2-1-3-13(5-12)23-18-15-4-11-7-22-24(8-14(26)9-25)17(11)6-16(15)20-10-21-18/h1-7,10,14,25-26H,8-9H2,(H,20,21,23)	YSBALMSOJQNWOI-UHFFFAOYSA-N	3625	3-{5-[(3-bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazolin-1-yl}propane-1,2-diol::5-[(3-bromophenyl)amino]-1-(2,3-dihydroxypropyl)pyrazolo[4,3-g]quinazoline::Pyrazoloquinazoline deriv. 2c	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3625	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3625&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328281	8033345							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5388	CN(C)CCn1ncc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C19H19BrN6/c1-25(2)6-7-26-18-10-17-16(8-13(18)11-23-26)19(22-12-21-17)24-15-5-3-4-14(20)9-15/h3-5,8-12H,6-7H2,1-2H3,(H,21,22,24)	LBVQCWSCVVKPQR-UHFFFAOYSA-N	3626	N-(3-bromophenyl)-1-[2-(dimethylamino)ethyl]-1H-pyrazolo[4,3-g]quinazolin-5-amine::5-[(3-Bromophenyl)amino]-1-[2-(N,N-dimethylamino)ethyl]pyrazolo[4,3-g]quinazoline::Pyrazoloquinazoline deriv. 2d	Epidermal growth factor receptor	Homo sapiens		 40					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3626&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328282	8033346							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5389	Brc1cccc(Nc2ncnc3cc4n(CCN5CCOCC5)ncc4cc23)c1	InChI=1S/C21H21BrN6O/c22-16-2-1-3-17(11-16)26-21-18-10-15-13-25-28(5-4-27-6-8-29-9-7-27)20(15)12-19(18)23-14-24-21/h1-3,10-14H,4-9H2,(H,23,24,26)	ZNHHYTFVIUDETO-UHFFFAOYSA-N	3627	5-[(3-Bromophenyl)amino]-1-[2-(4-morpholino)ethyl]-pyrazolo[4,3-g]quinazoline::N-(3-bromophenyl)-1-[2-(morpholin-4-yl)ethyl]-1H-pyrazolo[4,3-g]quinazolin-5-amine::Pyrazoloquinazoline deriv. 2f	Epidermal growth factor receptor	Homo sapiens		 3.7					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3627	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3627&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328283	8033347							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5390	OC(=O)Cn1ncc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C17H12BrN5O2/c18-11-2-1-3-12(5-11)22-17-13-4-10-7-21-23(8-16(24)25)15(10)6-14(13)19-9-20-17/h1-7,9H,8H2,(H,24,25)(H,19,20,22)	CFJDWNWGKOBXBC-UHFFFAOYSA-N	3628	5-[(3-bromophenyl)amino]-pyrazolo[4,3-g]quinazoline-1-acetic acid::2-{5-[(3-bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazolin-1-yl}acetic acid::Pyrazoloquinazoline deriv. 2h	Epidermal growth factor receptor	Homo sapiens		 53					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3628	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3628&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328284	8033348							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5391	Brc1cccc(Nc2ncnc3cc4[nH]ccc4cc23)c1	InChI=1S/C16H11BrN4/c17-11-2-1-3-12(7-11)21-16-13-6-10-4-5-18-14(10)8-15(13)19-9-20-16/h1-9,18H,(H,19,20,21)	BBFWQWIFLDQYQQ-UHFFFAOYSA-N	3583	Pyrroloquinazoline deriv. 3a::Anilinopyrimidine deriv. 7b::5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazoline::N-(3-bromophenyl)-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 21	Epidermal growth factor receptor	Homo sapiens		 0.44					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3583&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328243	8033306							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5392	Cn1ccc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C17H13BrN4/c1-22-6-5-11-7-14-15(9-16(11)22)19-10-20-17(14)21-13-4-2-3-12(18)8-13/h2-10H,1H3,(H,19,20,21)	QHAWLYRLLOXJAY-UHFFFAOYSA-N	3630	N-(3-bromophenyl)-8-methyl-8H-pyrrolo[3,2-g]quinazolin-4-amine::5-[(3-Bromophenyl)amino]-1-methylpyrrolo[3,2-g]-quinazoline::Pyrroloquinazoline deriv. 3b	Epidermal growth factor receptor	Homo sapiens		 0.80					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3630	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3630&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328285	8033349							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5393	OCC(O)Cn1ccc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C19H17BrN4O2/c20-13-2-1-3-14(7-13)23-19-16-6-12-4-5-24(9-15(26)10-25)18(12)8-17(16)21-11-22-19/h1-8,11,15,25-26H,9-10H2,(H,21,22,23)	VBSAGPWININOEH-UHFFFAOYSA-N	3631	5-[(3-Bromophenyl)amino]-1-(2,3-dihydroxypropyl)-pyrrolo[3,2-g]quinazoline::3-{4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-8-yl}propane-1,2-diol::Pyrroloquinazoline deriv. 3c	Epidermal growth factor receptor	Homo sapiens		 1.6					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3631&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328286	8033350							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5394	CN(C)CCn1ccc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C20H20BrN5/c1-25(2)8-9-26-7-6-14-10-17-18(12-19(14)26)22-13-23-20(17)24-16-5-3-4-15(21)11-16/h3-7,10-13H,8-9H2,1-2H3,(H,22,23,24)	PUGPTATVELXSCS-UHFFFAOYSA-N	3632	5-[(3-Bromophenyl)amino]-1-[2-(N,N-dimethylamino)-ethyl]pyrrolo[3,2-g]quinazoline::N-(3-bromophenyl)-8-[2-(dimethylamino)ethyl]-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 3d	Epidermal growth factor receptor	Homo sapiens		 41					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3632	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3632&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328287	8033351							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5395	CN(C)CCCn1ccc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C21H22BrN5/c1-26(2)8-4-9-27-10-7-15-11-18-19(13-20(15)27)23-14-24-21(18)25-17-6-3-5-16(22)12-17/h3,5-7,10-14H,4,8-9H2,1-2H3,(H,23,24,25)	KSESIAIRSPHRBJ-UHFFFAOYSA-N	3633	N-(3-bromophenyl)-8-[3-(dimethylamino)propyl]-8H-pyrrolo[3,2-g]quinazolin-4-amine::5-[(3-Bromophenyl)amino]-1-[3-(N,N-dimethylamino)-propyl]pyrrolo[3,2-g]quinazoline::Pyrroloquinazoline deriv. 3e	Epidermal growth factor receptor	Homo sapiens		 21					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3633	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3633&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328288	8033352							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5396	Brc1cccc(Nc2ncnc3cc4n(CCN5CCOCC5)ccc4cc23)c1	InChI=1S/C22H22BrN5O/c23-17-2-1-3-18(13-17)26-22-19-12-16-4-5-28(7-6-27-8-10-29-11-9-27)21(16)14-20(19)24-15-25-22/h1-5,12-15H,6-11H2,(H,24,25,26)	SZOXQULADAMXOQ-UHFFFAOYSA-N	3634	5-[(3-Bromophenyl)amino]-1-[2-(4-morpholino)ethyl]-pyrrolo[3,2-g]quinazoline::N-(3-bromophenyl)-8-[2-(morpholin-4-yl)ethyl]-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 3f	Epidermal growth factor receptor	Homo sapiens		 3.7					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3634	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3634&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328289	8033353							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5397	Brc1cccc(Nc2ncnc3cc4n(CCCN5CCOCC5)ccc4cc23)c1	InChI=1S/C23H24BrN5O/c24-18-3-1-4-19(14-18)27-23-20-13-17-5-8-29(22(17)15-21(20)25-16-26-23)7-2-6-28-9-11-30-12-10-28/h1,3-5,8,13-16H,2,6-7,9-12H2,(H,25,26,27)	NFCOOGUSNHUTQY-UHFFFAOYSA-N	3635	N-(3-bromophenyl)-8-[3-(morpholin-4-yl)propyl]-8H-pyrrolo[3,2-g]quinazolin-4-amine::5-[(3-Bromophenyl)amino]-1-[3-(4-morpholino)propyl]-pyrrolo[3,2-g]quinazoline::Pyrroloquinazoline deriv. 3g	Epidermal growth factor receptor	Homo sapiens		 8.8					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3635	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3635&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328290	8033354							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5398	OC(=O)Cn1ccc2cc3c(Nc4cccc(Br)c4)ncnc3cc12	InChI=1S/C18H13BrN4O2/c19-12-2-1-3-13(7-12)22-18-14-6-11-4-5-23(9-17(24)25)16(11)8-15(14)20-10-21-18/h1-8,10H,9H2,(H,24,25)(H,20,21,22)	CBFIWURGLMUIDN-UHFFFAOYSA-N	3636	5-[(3-Bromophenyl)amino]pyrrolo[3,2-g]quinazoline-1-acetic Acid::2-{4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-8-yl}acetic acid::Pyrroloquinazoline deriv. 3h	Epidermal growth factor receptor	Homo sapiens		 5.1					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3636&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328291	8033355							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5399	OCCN(CCO)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12	InChI=1S/C21H22BrN5O2/c22-15-2-1-3-16(8-15)26-21-18-9-17-14(12-27(4-6-28)5-7-29)11-23-19(17)10-20(18)24-13-25-21/h1-3,8-11,13,23,28-29H,4-7,12H2,(H,24,25,26)	OSXILVFPMQVTSK-UHFFFAOYSA-N	3637	5-[(3-Bromophenyl)amino]-3-[[N,N-bis(2-hydroxyethyl)amino]methyl]pyrrolo[3,2-g]quinazoline::2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-6-yl}methyl)(2-hydroxyethyl)amino]ethan-1-ol::Pyrroloquinazoline deriv. 4	Epidermal growth factor receptor	Homo sapiens		 3.5					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3637&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328292	8033356							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5400	CN(C)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12	InChI=1S/C19H18BrN5/c1-25(2)10-12-9-21-17-8-18-16(7-15(12)17)19(23-11-22-18)24-14-5-3-4-13(20)6-14/h3-9,11,21H,10H2,1-2H3,(H,22,23,24)	IGDHQJMAOBJFFR-UHFFFAOYSA-N	3638	N-(3-bromophenyl)-6-[(dimethylamino)methyl]-8H-pyrrolo[3,2-g]quinazolin-4-amine::5-[(3-Bromophenyl)amino]-3-[(N,N-dimethylamino)-methyl]pyrrolo[3,2-g]quinazoline::Pyrroloquinazoline deriv. 5	Epidermal growth factor receptor	Homo sapiens		 2.6					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3638	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3638&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328293	8033357							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5401	Brc1cccc(Nc2ncnc3cc4[nH]cc(CN5CCOCC5)c4cc23)c1	InChI=1S/C21H20BrN5O/c22-15-2-1-3-16(8-15)26-21-18-9-17-14(12-27-4-6-28-7-5-27)11-23-19(17)10-20(18)24-13-25-21/h1-3,8-11,13,23H,4-7,12H2,(H,24,25,26)	GQMMJLLDUVOKED-UHFFFAOYSA-N	3639	N-(3-bromophenyl)-6-(morpholin-4-ylmethyl)-8H-pyrrolo[3,2-g]quinazolin-4-amine::5-[(3-Bromophenyl)amino]-3-[(4-morpholino)methyl]-pyrrolo[3,2-g]quinazoline::Pyrroloquinazoline deriv. 6	Epidermal growth factor receptor	Homo sapiens		 4.8					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3639	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3639&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328294	8033358							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5402	CN(C)CCN(C)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12	InChI=1S/C22H25BrN6/c1-28(2)7-8-29(3)13-15-12-24-20-11-21-19(10-18(15)20)22(26-14-25-21)27-17-6-4-5-16(23)9-17/h4-6,9-12,14,24H,7-8,13H2,1-3H3,(H,25,26,27)	ZGDBKHJMLZCBJH-UHFFFAOYSA-N	3640	5-[(3-Bromophenyl)amino]-3-[(N,N,N-trimethylethylenediamino)methyl]pyrrolo[3,2-g]quinazoline::N-(3-bromophenyl)-6-({[2-(dimethylamino)ethyl](methyl)amino}methyl)-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 7	Epidermal growth factor receptor	Homo sapiens		 7.5					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3640	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3640&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328295	8033359							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5403	COC(=O)CN(C)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12	InChI=1S/C21H20BrN5O2/c1-27(11-20(28)29-2)10-13-9-23-18-8-19-17(7-16(13)18)21(25-12-24-19)26-15-5-3-4-14(22)6-15/h3-9,12,23H,10-11H2,1-2H3,(H,24,25,26)	OHXRQVMKFRLRKO-UHFFFAOYSA-N	3641	5-[(3-Bromophenyl)amino]-3-[[N-(carboxymethyl)-N-methylamino]methyl]pyrrolo[3,2-g]quinazoline ethyl ester::methyl 2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-6-yl}methyl)(methyl)amino]acetate::Pyrroloquinazoline deriv. 8	Epidermal growth factor receptor	Homo sapiens		 3.4					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3641&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328296	8033360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5404	CN(CC(O)=O)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12	InChI=1S/C20H18BrN5O2/c1-26(10-19(27)28)9-12-8-22-17-7-18-16(6-15(12)17)20(24-11-23-18)25-14-4-2-3-13(21)5-14/h2-8,11,22H,9-10H2,1H3,(H,27,28)(H,23,24,25)	DBSQOKFNDAENBI-UHFFFAOYSA-N	3642	5-[(3-bromophenyl)amino]-3-[[N-(carboxymethyl)-N-methylamino]methyl]pyrrolo[3,2-g]quinazoline hydrochloride::2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-6-yl}methyl)(methyl)amino]acetic acid::Pyrroloquinazoline deriv. 9	Epidermal growth factor receptor	Homo sapiens		 0.72					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm960789h	10.7270/Q2SJ1HRQ	9154973	aid1795551		Palmer, BD; Trumpp-Kallmeyer, S; Fry, DW; Nelson, JM; Showalter, HD; Denny, WA	5/9/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3642	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3642&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328297	8033361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5405	Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	SFUYILVZGXHCDG-UHFFFAOYSA-N	3309	4-N-(3-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-amino-4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidine::CHEMBL52076::7-Aminopyrido[4,3-d]pyrimidine 7f	Epidermal growth factor receptor	Homo sapiens		 10					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			382059	8033051		CHEMBL52076					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5406	CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C14H12BrN5/c1-16-13-6-12-11(7-17-13)14(19-8-18-12)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)	SOVBDLAXFPZPCR-UHFFFAOYSA-N	3594	4-N-(3-bromophenyl)-7-N-methylpyrido[4,3-d]pyrimidine-4,7-diamine::CHEMBL54400::4-[(3-Bromophenyl)amino]-7-(methylamino)pyrido[4,3-d]pyrimidine::Pyrido[4,3-d]pyrimidine 5f	Epidermal growth factor receptor	Homo sapiens		 0.13					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3594&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328252	8033315		CHEMBL54400					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5407	CN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C15H14BrN5/c1-21(2)14-7-13-12(8-17-14)15(19-9-18-13)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)	FKFFXIBNVYSRTJ-UHFFFAOYSA-N	3595	4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-(dimethylamino)pyrido-[4,3-d]pyrimidine::CHEMBL53428::Pyrido[4,3-d]pyrimidine 5g	Epidermal growth factor receptor	Homo sapiens		 0.09					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3595	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3595&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328253	8033316		CHEMBL53428					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5408	OCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C15H14BrN5O/c16-10-2-1-3-11(6-10)21-15-12-8-18-14(17-4-5-22)7-13(12)19-9-20-15/h1-3,6-9,22H,4-5H2,(H,17,18)(H,19,20,21)	BGHDMTQKOHCXGS-UHFFFAOYSA-N	3646	2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)ethan-1-ol::4-[(3-Bromophenyl)amino]-7-[(2-hydroxyethyl)amino]-pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3d	Epidermal growth factor receptor	Homo sapiens		 0.24					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3646	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3646&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328298	8033362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5409	CN(CCO)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C16H16BrN5O/c1-22(5-6-23)15-8-14-13(9-18-15)16(20-10-19-14)21-12-4-2-3-11(17)7-12/h2-4,7-10,23H,5-6H2,1H3,(H,19,20,21)	FXWAFRDJXXFRPI-UHFFFAOYSA-N	3647	2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(methyl)amino)ethan-1-ol::4-[(3-Bromophenyl)amino]-7-[N-(2-hydroxyethyl)-N-methylamino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3e	Epidermal growth factor receptor	Homo sapiens		 2.6					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3647	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3647&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328299	8033363							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5410	OCC(O)CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C16H16BrN5O2/c17-10-2-1-3-11(4-10)22-16-13-7-19-15(18-6-12(24)8-23)5-14(13)20-9-21-16/h1-5,7,9,12,23-24H,6,8H2,(H,18,19)(H,20,21,22)	JLXPNVOGDZTOJF-UHFFFAOYSA-N	3648	3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propane-1,2-diol::4-[(3-Bromophenyl)amino]-7-[(2,3-dihydroxypropyl)-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3f	Epidermal growth factor receptor	Homo sapiens		 0.92					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3648	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3648&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328300	8033364							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5411	CN(CC(O)CO)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C17H18BrN5O2/c1-23(8-13(25)9-24)16-6-15-14(7-19-16)17(21-10-20-15)22-12-4-2-3-11(18)5-12/h2-7,10,13,24-25H,8-9H2,1H3,(H,20,21,22)	VHMBNNHFFIJPIQ-UHFFFAOYSA-N	3649	4-[(3-Bromophenyl)amino]-7-[N-(2,3-dihydroxypropyl)-N-methylamino]pyrido[4,3-d]pyrimidine::3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(methyl)amino)propane-1,2-diol::pyrido[4,3-d]pyrimidine deriv. 3g	Epidermal growth factor receptor	Homo sapiens		 3.2					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3649	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3649&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328301	8033365							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5412	OCC(CO)Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C16H16BrN5O2/c17-10-2-1-3-11(4-10)22-16-13-6-18-15(21-12(7-23)8-24)5-14(13)19-9-20-16/h1-6,9,12,23-24H,7-8H2,(H,18,21)(H,19,20,22)	ANVYMDPUMZNGLO-UHFFFAOYSA-N	3650	4-[(3-Bromophenyl)amino]-7-[(1,3-dihydroxy-2-propyl)amino]pyrido[4,3-d]pyrimidine::2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propane-1,3-diol::pyrido[4,3-d]pyrimidine deriv. 3h	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3650	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3650&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328302	8033366							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5413	OCCN(CCO)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C17H18BrN5O2/c18-12-2-1-3-13(8-12)22-17-14-10-19-16(9-15(14)20-11-21-17)23(4-6-24)5-7-25/h1-3,8-11,24-25H,4-7H2,(H,20,21,22)	LYENTQSFLVZYRJ-UHFFFAOYSA-N	3651	2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(2-hydroxyethyl)amino)ethan-1-ol::4-[(3-Bromophenyl)amino]-7-[N,N-bis(2-hydroxyethyl)amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3i	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3651&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328303	8033367							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5414	OCC(O)C(O)C(O)C(O)CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C19H22BrN5O5/c20-10-2-1-3-11(4-10)25-19-12-6-21-16(5-13(12)23-9-24-19)22-7-14(27)17(29)18(30)15(28)8-26/h1-6,9,14-15,17-18,26-30H,7-8H2,(H,21,22)(H,23,24,25)	CHHPKSCSIBSQIU-UHFFFAOYSA-N	3652	6-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)hexane-1,2,3,4,5-pentol::4-[(3-Bromophenyl)amino]-7-D-glucaminopyrido[4,3-d]-pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3j	Epidermal growth factor receptor	Homo sapiens		 4.8					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3652	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3652&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328304	8033368							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5415	CN(CC(O)C(O)C(O)C(O)CO)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C20H24BrN5O5/c1-26(8-15(28)18(30)19(31)16(29)9-27)17-6-14-13(7-22-17)20(24-10-23-14)25-12-4-2-3-11(21)5-12/h2-7,10,15-16,18-19,27-31H,8-9H2,1H3,(H,23,24,25)	OUDUEUZRZJNOKY-UHFFFAOYSA-N	3653	4-[(3-Bromophenyl)amino]-7-(N-methyl-D-glucamino)-pyrido[4,3-d]pyrimidine::6-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(methyl)amino)hexane-1,2,3,4,5-pentol::pyrido[4,3-d]pyrimidine deriv. 3k	Epidermal growth factor receptor	Homo sapiens		 3.2					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3653	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3653&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328305	8033369							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5416	CN(C)CCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C17H19BrN6/c1-24(2)7-6-19-16-9-15-14(10-20-16)17(22-11-21-15)23-13-5-3-4-12(18)8-13/h3-5,8-11H,6-7H2,1-2H3,(H,19,20)(H,21,22,23)	YOKVZXZOOHPMFL-UHFFFAOYSA-N	3654	4-N-(3-bromophenyl)-7-N-[2-(dimethylamino)ethyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[2-(dimethylamino)ethyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3l	Epidermal growth factor receptor	Homo sapiens		 45					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3654	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3654&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328306	8033370							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5417	CN(C)CCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C18H21BrN6/c1-25(2)8-4-7-20-17-10-16-15(11-21-17)18(23-12-22-16)24-14-6-3-5-13(19)9-14/h3,5-6,9-12H,4,7-8H2,1-2H3,(H,20,21)(H,22,23,24)	KQABJETUKXUAAM-UHFFFAOYSA-N	3655	4-N-(3-bromophenyl)-7-N-[3-(dimethylamino)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[3-(dimethylamino)propyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3m	Epidermal growth factor receptor	Homo sapiens		 8.8					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3655	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3655&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328307	8033371							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5418	CN(C)CCCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C19H23BrN6/c1-26(2)9-4-3-8-21-18-11-17-16(12-22-18)19(24-13-23-17)25-15-7-5-6-14(20)10-15/h5-7,10-13H,3-4,8-9H2,1-2H3,(H,21,22)(H,23,24,25)	IQMLUMTUZSQCPT-UHFFFAOYSA-N	3656	4-N-(3-bromophenyl)-7-N-[4-(dimethylamino)butyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[4-(dimethylamino)butyl]-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3n	Epidermal growth factor receptor	Homo sapiens		 7.4					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3656	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3656&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328308	8033372							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5419	CN(C)CCCCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C20H25BrN6/c1-27(2)10-5-3-4-9-22-19-12-18-17(13-23-19)20(25-14-24-18)26-16-8-6-7-15(21)11-16/h6-8,11-14H,3-5,9-10H2,1-2H3,(H,22,23)(H,24,25,26)	QAUQFKRIRRUBIU-UHFFFAOYSA-N	3657	4-N-(3-bromophenyl)-7-N-[5-(dimethylamino)pentyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[5-(dimethylamino)pentyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3o	Epidermal growth factor receptor	Homo sapiens		 8.4					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3657	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3657&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328309	8033373							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5420	CN(C)CCN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C18H21BrN6/c1-24(2)7-8-25(3)17-10-16-15(11-20-17)18(22-12-21-16)23-14-6-4-5-13(19)9-14/h4-6,9-12H,7-8H2,1-3H3,(H,21,22,23)	SXQLAYKKOJLZRB-UHFFFAOYSA-N	3658	4-N-(3-bromophenyl)-7-N-[2-(dimethylamino)ethyl]-7-N-methylpyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[N-[2-(dimethylamino)-ethyl]-N-methylamino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3p	Epidermal growth factor receptor	Homo sapiens		 40					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3658	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3658&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328310	8033374							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5421	Brc1cccc(Nc2ncnc3cc(NCCN4CCOCC4)ncc23)c1	InChI=1S/C19H21BrN6O/c20-14-2-1-3-15(10-14)25-19-16-12-22-18(11-17(16)23-13-24-19)21-4-5-26-6-8-27-9-7-26/h1-3,10-13H,4-9H2,(H,21,22)(H,23,24,25)	RHIKOEXNOGXDPV-UHFFFAOYSA-N	3659	4-N-(3-bromophenyl)-7-N-[2-(morpholin-4-yl)ethyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[2-(4-morpholino)ethyl]-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3q	Epidermal growth factor receptor	Homo sapiens		 3.2					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3659	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3659&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328311	8033375							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5422	Brc1cccc(Nc2ncnc3cc(NCCCN4CCOCC4)ncc23)c1	InChI=1S/C20H23BrN6O/c21-15-3-1-4-16(11-15)26-20-17-13-23-19(12-18(17)24-14-25-20)22-5-2-6-27-7-9-28-10-8-27/h1,3-4,11-14H,2,5-10H2,(H,22,23)(H,24,25,26)	WPUBKZIJROOKPL-UHFFFAOYSA-N	3660	4-N-(3-bromophenyl)-7-N-[3-(morpholin-4-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[3-(4-morpholino)propyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3r	Epidermal growth factor receptor	Homo sapiens		 1.9					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3660	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3660&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328312	8033376							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5423	Brc1cccc(Nc2ncnc3cc(NCCCCN4CCOCC4)ncc23)c1	InChI=1S/C21H25BrN6O/c22-16-4-3-5-17(12-16)27-21-18-14-24-20(13-19(18)25-15-26-21)23-6-1-2-7-28-8-10-29-11-9-28/h3-5,12-15H,1-2,6-11H2,(H,23,24)(H,25,26,27)	LGQGASCJEHGWJL-UHFFFAOYSA-N	3661	4-N-(3-bromophenyl)-7-N-[4-(morpholin-4-yl)butyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[4-(4-morpholino)butyl]-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3s	Epidermal growth factor receptor	Homo sapiens		 5.4							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3661	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3661&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328313	8033377							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5424	[O-][N+]1(CCCNc2cc3ncnc(Nc4cccc(Br)c4)c3cn2)CCOCC1	InChI=1S/C20H23BrN6O2/c21-15-3-1-4-16(11-15)26-20-17-13-23-19(12-18(17)24-14-25-20)22-5-2-6-27(28)7-9-29-10-8-27/h1,3-4,11-14H,2,5-10H2,(H,22,23)(H,24,25,26)	NMCVYFXROBUBLX-UHFFFAOYSA-N	3662	4-[3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propyl]-4-oxidomorpholin-4-ium::4-[(3-Bromophenyl)amino]-7-[[3-(4-morpholino)propyl]amino]pyrido[4,3-d]pyrimidine N1 -Oxide::pyrido[4,3-d]pyrimidine deriv. 3t	Epidermal growth factor receptor	Homo sapiens		 0.74							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3662&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328314	8033378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5425	CN1CCN(CCCNc2cc3ncnc(Nc4cccc(Br)c4)c3cn2)CC1	InChI=1S/C21H26BrN7/c1-28-8-10-29(11-9-28)7-3-6-23-20-13-19-18(14-24-20)21(26-15-25-19)27-17-5-2-4-16(22)12-17/h2,4-5,12-15H,3,6-11H2,1H3,(H,23,24)(H,25,26,27)	AEPFNBDPODWKEH-UHFFFAOYSA-N	3663	4-[(3-Bromophenyl)amino]-7-[[3-(4-methylpiperazin-1-yl)propyl]amino]pyrido[4,3-d]pyrimidine::4-N-(3-bromophenyl)-7-N-[3-(4-methylpiperazin-1-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::pyrido[4,3-d]pyrimidine deriv. 3u	Epidermal growth factor receptor	Homo sapiens		 4.9							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3663	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3663&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328315	8033379							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5426	OCCN(CCO)CCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C19H23BrN6O2/c20-14-2-1-3-15(10-14)25-19-16-12-22-18(11-17(16)23-13-24-19)21-4-5-26(6-8-27)7-9-28/h1-3,10-13,27-28H,4-9H2,(H,21,22)(H,23,24,25)	NOLLIFGERWLBPP-UHFFFAOYSA-N	3664	4-[(3-Bromophenyl)amino]-7-[[2-[N,N-bis(2-hydroxyethyl)amino]ethyl]amino]pyrido[4,3-d]pyrimidine::2-{[2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)ethyl](2-hydroxyethyl)amino}ethan-1-ol::pyrido[4,3-d]pyrimidine deriv. 3v	Epidermal growth factor receptor	Homo sapiens		 9.2							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3664&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328316	8033380							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5427	OCCN(CCO)CCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C20H25BrN6O2/c21-15-3-1-4-16(11-15)26-20-17-13-23-19(12-18(17)24-14-25-20)22-5-2-6-27(7-9-28)8-10-29/h1,3-4,11-14,28-29H,2,5-10H2,(H,22,23)(H,24,25,26)	WCVWPEWJCFWBAJ-UHFFFAOYSA-N	3665	2-{[3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propyl](2-hydroxyethyl)amino}ethan-1-ol::4-[(3-Bromophenyl)amino]-7-[[3-[N,N-bis(2-hydroxyethyl)amino]propyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3w	Epidermal growth factor receptor	Homo sapiens		 1.2							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3665	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3665&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328317	8033381							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5428	NNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C13H11BrN6/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(20-15)5-11(10)17-7-18-13/h1-7H,15H2,(H,16,20)(H,17,18,19)	XKJIVVHNSBAGCH-UHFFFAOYSA-N	3666	4-[(3-Bromophenyl)amino]-7-hydrazinopyrido[4,3-d]-pyrimidine::N-(3-bromophenyl)-7-hydrazinylpyrido[4,3-d]pyrimidin-4-amine::pyrido[4,3-d]pyrimidine deriv. 3x	Epidermal growth factor receptor	Homo sapiens		 7.1							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3666	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3666&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328318	8033382							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5429	Brc1cccc(Nc2ncnc3cc(NCCCn4ccnc4)ncc23)c1	InChI=1S/C19H18BrN7/c20-14-3-1-4-15(9-14)26-19-16-11-23-18(10-17(16)24-12-25-19)22-5-2-7-27-8-6-21-13-27/h1,3-4,6,8-13H,2,5,7H2,(H,22,23)(H,24,25,26)	QENYREVCVOGEQU-UHFFFAOYSA-N	3667	4-[(3-Bromophenyl)amino]-7-[[3-(imidazol-1-yl)propyl]-amino]pyrido[4,3-d]pyrimidine::4-N-(3-bromophenyl)-7-N-[3-(1H-imidazol-1-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::pyrido[4,3-d]pyrimidine deriv. 3y	Epidermal growth factor receptor	Homo sapiens		 0.51							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3667	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3667&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328319	8033383							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5430	Brc1cccc(Nc2ncnc3cc(NCCc4cnc[nH]4)ncc23)c1	InChI=1S/C18H16BrN7/c19-12-2-1-3-13(6-12)26-18-15-9-22-17(7-16(15)24-11-25-18)21-5-4-14-8-20-10-23-14/h1-3,6-11H,4-5H2,(H,20,23)(H,21,22)(H,24,25,26)	PFJRPGGNJFXXDJ-UHFFFAOYSA-N	3668	4-N-(3-bromophenyl)-7-N-[2-(1H-imidazol-4-yl)ethyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[2-(imidazol-4-yl)ethyl]-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3z	Epidermal growth factor receptor	Homo sapiens		 0.91							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3668&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328320	8033384							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5431	OC(=O)CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C15H12BrN5O2/c16-9-2-1-3-10(4-9)21-15-11-6-17-13(18-7-14(22)23)5-12(11)19-8-20-15/h1-6,8H,7H2,(H,17,18)(H,22,23)(H,19,20,21)	DNUPNCOEFDVRHA-UHFFFAOYSA-N	3669	2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)acetic acid::4-[(3-Bromophenyl)amino]-7-[(carboxymethyl)amino]-pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3aa	Epidermal growth factor receptor	Homo sapiens		 1.5							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3669	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3669&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328321	8033385							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5432	OC(=O)CCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C16H14BrN5O2/c17-10-2-1-3-11(6-10)22-16-12-8-19-14(18-5-4-15(23)24)7-13(12)20-9-21-16/h1-3,6-9H,4-5H2,(H,18,19)(H,23,24)(H,20,21,22)	SRQBKAXEENMWFO-UHFFFAOYSA-N	3670	4-[(3-Bromophenyl)amino]-7-[(2-carboxyethyl)amino]-pyrido[4,3-d]pyrimidine::3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propanoic acid::pyrido[4,3-d]pyrimidine deriv. 3bb	Epidermal growth factor receptor	Homo sapiens		 0.61							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3670	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3670&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328322	8033386							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5433	OC(=O)CCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C17H16BrN5O2/c18-11-3-1-4-12(7-11)23-17-13-9-20-15(8-14(13)21-10-22-17)19-6-2-5-16(24)25/h1,3-4,7-10H,2,5-6H2,(H,19,20)(H,24,25)(H,21,22,23)	AORLUMDMFWSHLT-UHFFFAOYSA-N	3671	4-[(3-Bromophenyl)amino]-7-[(3-carboxypropyl)amino]-pyrido[4,3-d]pyrimidine::4-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)butanoic acid::pyrido[4,3-d]pyrimidine deriv. 3cc	Epidermal growth factor receptor	Homo sapiens		 0.28							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3671	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3671&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328323	8033387							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5434	CN(CC(O)=O)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C16H14BrN5O2/c1-22(8-15(23)24)14-6-13-12(7-18-14)16(20-9-19-13)21-11-4-2-3-10(17)5-11/h2-7,9H,8H2,1H3,(H,23,24)(H,19,20,21)	GYZRHMIPWQOSOA-UHFFFAOYSA-N	3672	4-[(3-Bromophenyl)amino]-7-[N-(carboxymethyl)-N-methylamino]pyrido[4,3-d]pyrimidine::2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(methyl)amino)acetic acid::pyrido[4,3-d]pyrimidine deriv. 3dd	Epidermal growth factor receptor	Homo sapiens		 16							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3672	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3672&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328324	8033388							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5435	OS(=O)(=O)CCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1	InChI=1S/C15H14BrN5O3S/c16-10-2-1-3-11(6-10)21-15-12-8-18-14(7-13(12)19-9-20-15)17-4-5-25(22,23)24/h1-3,6-9H,4-5H2,(H,17,18)(H,19,20,21)(H,22,23,24)	KFKHOLUDECOBTE-UHFFFAOYSA-N	3673	2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)ethane-1-sulfonic acid::4-[(3-Bromophenyl)amino]-7-(sulfoethylamino)pyrido-[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3ee	Epidermal growth factor receptor	Homo sapiens		 1.4							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3673	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3673&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328325	8033389					C15521		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5436	CNc1cc2ncnc(Nc3cccc(C)c3)c2cn1	InChI=1S/C15H15N5/c1-10-4-3-5-11(6-10)20-15-12-8-17-14(16-2)7-13(12)18-9-19-15/h3-9H,1-2H3,(H,16,17)(H,18,19,20)	YAVCJZFLGRQKCZ-UHFFFAOYSA-N	3674	7-(Methylamino)-4-[(3-methylphenyl)amino]pyrido-[4,3-d]pyrimidine::7-N-methyl-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::pyrido[4,3-d]pyrimidine deriv. 4b	Epidermal growth factor receptor	Homo sapiens		 1.4							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3674	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3674&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328326	8033390							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5437	CN(C)CCCCNc1cc2ncnc(Nc3cccc(C)c3)c2cn1	InChI=1S/C20H26N6/c1-15-7-6-8-16(11-15)25-20-17-13-22-19(12-18(17)23-14-24-20)21-9-4-5-10-26(2)3/h6-8,11-14H,4-5,9-10H2,1-3H3,(H,21,22)(H,23,24,25)	ANAQVLGHFOBDLP-UHFFFAOYSA-N	3675	7-[[4-(Dimethylamino)butyl]amino]-4-[(3-methylphenyl)amino]pyrido[4,3-d]pyrimidine::7-N-[4-(dimethylamino)butyl]-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::pyrido[4,3-d]pyrimidine deriv. 4n	Epidermal growth factor receptor	Homo sapiens		 5.4							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3675	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3675&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328327	8033391							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5438	Cc1cccc(Nc2ncnc3cc(NCCCN4CCOCC4)ncc23)c1	InChI=1S/C21H26N6O/c1-16-4-2-5-17(12-16)26-21-18-14-23-20(13-19(18)24-15-25-21)22-6-3-7-27-8-10-28-11-9-27/h2,4-5,12-15H,3,6-11H2,1H3,(H,22,23)(H,24,25,26)	YBNNPKWJNJBQNZ-UHFFFAOYSA-N	3676	4-N-(3-methylphenyl)-7-N-[3-(morpholin-4-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Methylphenyl)amino]-7-[[3-(4-morpholino)propyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 4r	Epidermal growth factor receptor	Homo sapiens		 9.3							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3676&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328328	8033392							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5439	CN1CCN(CCCNc2cc3ncnc(Nc4cccc(C)c4)c3cn2)CC1	InChI=1S/C22H29N7/c1-17-5-3-6-18(13-17)27-22-19-15-24-21(14-20(19)25-16-26-22)23-7-4-8-29-11-9-28(2)10-12-29/h3,5-6,13-16H,4,7-12H2,1-2H3,(H,23,24)(H,25,26,27)	ZSWVFFAVTCICJD-UHFFFAOYSA-N	3677	4-[(3-Methylphenyl)amino]-7-[[3-(4-methylpiperazin-1-yl)propyl]amino]pyrido[4,3-d]pyrimidine::4-N-(3-methylphenyl)-7-N-[3-(4-methylpiperazin-1-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::pyrido[4,3-d]pyrimidine deriv. 4u	Epidermal growth factor receptor	Homo sapiens		 5.6							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3677	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3677&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328329	8033393							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5440	Cc1cccc(Nc2ncnc3cc(NCCCn4ccnc4)ncc23)c1	InChI=1S/C20H21N7/c1-15-4-2-5-16(10-15)26-20-17-12-23-19(11-18(17)24-13-25-20)22-6-3-8-27-9-7-21-14-27/h2,4-5,7,9-14H,3,6,8H2,1H3,(H,22,23)(H,24,25,26)	OKJBKEUQKDDCKF-UHFFFAOYSA-N	3678	7-N-[3-(1H-imidazol-1-yl)propyl]-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-[[3-(Imidazol-1-yl)propyl]amino]-4-[(3-methylphenyl)amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 4y	Epidermal growth factor receptor	Homo sapiens		 3.5							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3678	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3678&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328330	8033394							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5441	Cc1cccc(Nc2ncnc3cc(NCCc4cnc[nH]4)ncc23)c1	InChI=1S/C19H19N7/c1-13-3-2-4-14(7-13)26-19-16-10-22-18(8-17(16)24-12-25-19)21-6-5-15-9-20-11-23-15/h2-4,7-12H,5-6H2,1H3,(H,20,23)(H,21,22)(H,24,25,26)	YTEVJLKCRWIESE-UHFFFAOYSA-N	3679	7-N-[2-(1H-imidazol-4-yl)ethyl]-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-[[2-(Imidazol-4-yl)ethyl]amino]-4-[(3-methylphenyl)-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 4z	Epidermal growth factor receptor	Homo sapiens		 7.2							Curated from the literature by BindingDB	10.1021/jm970366v	10.7270/Q2NS0S2V	9397172	aid1795552		Thompson, AM; Murray, DK; Elliott, WL; Fry, DW; Nelson, JA; Showalter, HD; Roberts, BJ; Vincent, PW; Denny, WA	11/21/1997	3/8/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3679	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3679&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328331	8033395							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5442	Clc1ncc2ncnc(Nc3ccccc3)c2n1	InChI=1S/C12H8ClN5/c13-12-14-6-9-10(18-12)11(16-7-15-9)17-8-4-2-1-3-5-8/h1-7H,(H,15,16,17)	MBZZMOBHTIEAEW-UHFFFAOYSA-N	3680	6-Chloro-4-(phenylamino)pyrimido[5,4-d]pyrimidine::6-chloro-N-phenyl-[1,3]diazino[5,4-d]pyrimidin-4-amine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 4a	Epidermal growth factor receptor	Homo sapiens		 2550					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3680	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3680&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328332	8033396							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5443	CNc1ncc2ncnc(Nc3ccccc3)c2n1	InChI=1S/C13H12N6/c1-14-13-15-7-10-11(19-13)12(17-8-16-10)18-9-5-3-2-4-6-9/h2-8H,1H3,(H,14,15,19)(H,16,17,18)	HSTFDYRLOHVGKW-UHFFFAOYSA-N	3681	2-N-methyl-8-N-phenyl-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::6-(Methylamino)-4-(phenylamino)pyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 4c	Epidermal growth factor receptor	Homo sapiens		 13					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3681	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3681&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328333	8033397							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5444	Clc1ncc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C12H7BrClN5/c13-7-2-1-3-8(4-7)18-11-10-9(16-6-17-11)5-15-12(14)19-10/h1-6H,(H,16,17,18)	KIJZNASQHHBSGG-UHFFFAOYSA-N	3682	4-[(3-Bromophenyl)amino]-6-chloropyrimido[5,4-d]pyrimidine::N-(3-bromophenyl)-6-chloro-[1,3]diazino[5,4-d]pyrimidin-4-amine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5a	Epidermal growth factor receptor	Homo sapiens		 82					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3682	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3682&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328334	8033398							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5445	Nc1ncc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C12H9BrN6/c13-7-2-1-3-8(4-7)18-11-10-9(16-6-17-11)5-15-12(14)19-10/h1-6H,(H2,14,15,19)(H,16,17,18)	SJVLDEFAHRZRJJ-UHFFFAOYSA-N	3683	6-Amino-4-[(3-bromophenyl)amino]pyrimido[5,4-d]pyrimidine::8-N-(3-bromophenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5b	Epidermal growth factor receptor	Homo sapiens		 1.5					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3683	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3683&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328335	8033399							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5446	CNc1ncc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C13H11BrN6/c1-15-13-16-6-10-11(20-13)12(18-7-17-10)19-9-4-2-3-8(14)5-9/h2-7H,1H3,(H,15,16,20)(H,17,18,19)	SINHNCOFBIYLPM-UHFFFAOYSA-N	3684	8-N-(3-bromophenyl)-2-N-methyl-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-[(3-Bromophenyl)amino]-6-(methylamino)pyrimido-[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5c	Epidermal growth factor receptor	Homo sapiens		 0.76					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3684	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3684&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328336	8033400							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5447	CN(C)c1ncc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C14H13BrN6/c1-21(2)14-16-7-11-12(20-14)13(18-8-17-11)19-10-5-3-4-9(15)6-10/h3-8H,1-2H3,(H,17,18,19)	MEEGNTPYUPZJPV-UHFFFAOYSA-N	3685	4-[(3-Bromophenyl)amino]-6-(dimethylamino)pyrimido-[5,4-d]pyrimidine::8-N-(3-bromophenyl)-2-N,2-N-dimethyl-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5d	Epidermal growth factor receptor	Homo sapiens		 0.95					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3685&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328337	8033401							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5448	COc1ncc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C13H10BrN5O/c1-20-13-15-6-10-11(19-13)12(17-7-16-10)18-9-4-2-3-8(14)5-9/h2-7H,1H3,(H,16,17,18)	XFDJSPMIYIIGLF-UHFFFAOYSA-N	3686	N-(3-bromophenyl)-6-methoxy-[1,3]diazino[5,4-d]pyrimidin-4-amine::4-[(3-Bromophenyl)amino]-6-methoxypyrimido[5,4-d]-pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5e	Epidermal growth factor receptor	Homo sapiens		 3.8					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3686&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328338	8033402							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5449	CN(C)CCNc1ncc2ncnc(Nc3cccc(Br)c3)c2n1	InChI=1S/C16H18BrN7/c1-24(2)7-6-18-16-19-9-13-14(23-16)15(21-10-20-13)22-12-5-3-4-11(17)8-12/h3-5,8-10H,6-7H2,1-2H3,(H,18,19,23)(H,20,21,22)	BRXQCYKQKVTPNS-UHFFFAOYSA-N	3687	8-N-(3-bromophenyl)-2-N-[2-(dimethylamino)ethyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-[(3-Bromophenyl)amino]-6-[[2-(dimethylamino)-ethyl]amino]pyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5f	Epidermal growth factor receptor	Homo sapiens		 35					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3687&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328339	8033403							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5450	Brc1cccc(Nc2ncnc3cnc(NCCN4CCOCC4)nc23)c1	InChI=1S/C18H20BrN7O/c19-13-2-1-3-14(10-13)24-17-16-15(22-12-23-17)11-21-18(25-16)20-4-5-26-6-8-27-9-7-26/h1-3,10-12H,4-9H2,(H,20,21,25)(H,22,23,24)	FBSRQIPWINDALQ-UHFFFAOYSA-N	3688	4-[(3-Bromophenyl)amino]-6-[[2-(4-morpholino)ethyl]-amino]pyrimido[5,4-d]pyrimidine::8-N-(3-bromophenyl)-2-N-[2-(morpholin-4-yl)ethyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5g	Epidermal growth factor receptor	Homo sapiens		 0.81					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3688	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3688&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328340	8033404							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5451	Brc1cccc(Nc2ncnc3cnc(NCCCN4CCOCC4)nc23)c1	InChI=1S/C19H22BrN7O/c20-14-3-1-4-15(11-14)25-18-17-16(23-13-24-18)12-22-19(26-17)21-5-2-6-27-7-9-28-10-8-27/h1,3-4,11-13H,2,5-10H2,(H,21,22,26)(H,23,24,25)	AKSMEOTWWFYYSQ-UHFFFAOYSA-N	3689	8-N-(3-bromophenyl)-2-N-[3-(morpholin-4-yl)propyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-[(3-Bromophenyl)amino]-6-[[3-(4-morpholino)propyl]amino]pyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5h	Epidermal growth factor receptor	Homo sapiens		 2.9					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3689	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3689&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328341	8033405							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5452	Brc1cccc(Nc2ncnc3cnc(NCCc4cnc[nH]4)nc23)c1	InChI=1S/C17H15BrN8/c18-11-2-1-3-12(6-11)25-16-15-14(23-10-24-16)8-21-17(26-15)20-5-4-13-7-19-9-22-13/h1-3,6-10H,4-5H2,(H,19,22)(H,20,21,26)(H,23,24,25)	OBPPQMUVDDMIQI-UHFFFAOYSA-N	3690	8-N-(3-bromophenyl)-2-N-[2-(1H-imidazol-4-yl)ethyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-[(3-Bromophenyl)amino]-6-[[2-(4-imidazolyl)ethyl]amino]pyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5i	Epidermal growth factor receptor	Homo sapiens		 0.25					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3690	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3690&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328342	8033406							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5453	Brc1cccc(Nc2ncnc3cnc(NCCCn4ccnc4)nc23)c1	InChI=1S/C18H17BrN8/c19-13-3-1-4-14(9-13)25-17-16-15(23-11-24-17)10-22-18(26-16)21-5-2-7-27-8-6-20-12-27/h1,3-4,6,8-12H,2,5,7H2,(H,21,22,26)(H,23,24,25)	PHVFHKTZGHFXKK-UHFFFAOYSA-N	3691	4-[(3-Bromophenyl)amino]-6-[[3-(1-imidazolyl)propyl]amino]pyrimido[5,4-d]pyrimidine::8-N-(3-bromophenyl)-2-N-[3-(1H-imidazol-1-yl)propyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5j	Epidermal growth factor receptor	Homo sapiens		 2.3					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3691	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3691&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328343	8033407							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5454	Cc1cccc(Nc2ncnc3cnc(Cl)nc23)c1	InChI=1S/C13H10ClN5/c1-8-3-2-4-9(5-8)18-12-11-10(16-7-17-12)6-15-13(14)19-11/h2-7H,1H3,(H,16,17,18)	QMOSIXMIXVFZRG-UHFFFAOYSA-N	3692	4-[(3-Methylphenyl)amino]-6-chloropyrimido[5,4-d]pyrimidine::6-chloro-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidin-4-amine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6a	Epidermal growth factor receptor	Homo sapiens		 380					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3692	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3692&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328344	8033408							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5455	Cc1cccc(Nc2ncnc3cnc(N)nc23)c1	InChI=1S/C13H12N6/c1-8-3-2-4-9(5-8)18-12-11-10(16-7-17-12)6-15-13(14)19-11/h2-7H,1H3,(H2,14,15,19)(H,16,17,18)	OLZKKHBEDMOWRD-UHFFFAOYSA-N	3693	6-Amino-4-[(3-methylphenyl)amino]pyrimido[5,4-d]pyrimidine::8-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6b	Epidermal growth factor receptor	Homo sapiens		 17					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3693	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3693&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328345	8033409							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5456	CNc1ncc2ncnc(Nc3cccc(C)c3)c2n1	InChI=1S/C14H14N6/c1-9-4-3-5-10(6-9)19-13-12-11(17-8-18-13)7-16-14(15-2)20-12/h3-8H,1-2H3,(H,15,16,20)(H,17,18,19)	CKGJCAISFNGPHH-UHFFFAOYSA-N	3694	2-N-methyl-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::6-(Methylamino)-4-[(3-methylphenyl)amino]pyrimido-[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6c	Epidermal growth factor receptor	Homo sapiens		 4.3					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3694	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3694&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328346	8033410							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5457	CN(C)c1ncc2ncnc(Nc3cccc(C)c3)c2n1	InChI=1S/C15H16N6/c1-10-5-4-6-11(7-10)19-14-13-12(17-9-18-14)8-16-15(20-13)21(2)3/h4-9H,1-3H3,(H,17,18,19)	XQLOYQBOLORUIS-UHFFFAOYSA-N	3695	6-(Dimethylamino)-4-[(3-methylphenyl)amino]pyrimido[5,4-d]pyrimidine::2-N,2-N-dimethyl-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6d	Epidermal growth factor receptor	Homo sapiens		 4.0					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3695	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3695&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328347	8033411							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5458	Cc1cccc(Nc2ncnc3cnc(NCCN4CCOCC4)nc23)c1	InChI=1S/C19H23N7O/c1-14-3-2-4-15(11-14)24-18-17-16(22-13-23-18)12-21-19(25-17)20-5-6-26-7-9-27-10-8-26/h2-4,11-13H,5-10H2,1H3,(H,20,21,25)(H,22,23,24)	COTLDEHUICFEBP-UHFFFAOYSA-N	3696	4-[(3-Methylphenyl)amino]-6-[[2-(4-morpholino)ethyl]-amino]pyrimido[5,4-d]pyrimidine::8-N-(3-methylphenyl)-2-N-[2-(morpholin-4-yl)ethyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6g	Epidermal growth factor receptor	Homo sapiens		 2.3					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3696	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3696&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328348	8033412							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5459	Cc1cccc(Nc2ncnc3cnc(NCCc4cnc[nH]4)nc23)c1	InChI=1S/C18H18N8/c1-12-3-2-4-13(7-12)25-17-16-15(23-11-24-17)9-21-18(26-16)20-6-5-14-8-19-10-22-14/h2-4,7-11H,5-6H2,1H3,(H,19,22)(H,20,21,26)(H,23,24,25)	PPZFAINTCTWXKE-UHFFFAOYSA-N	3697	4-[(3-Methylphenyl)amino]-6-[[2-(4-imidazolyl)ethyl]amino]pyrimido[5,4-d]pyrimidine::2-N-[2-(1H-imidazol-4-yl)ethyl]-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6i	Epidermal growth factor receptor	Homo sapiens		 3.0					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960879m	10.7270/Q2J101C8	9191958	aid1795555		Rewcastle, GW; Bridges, AJ; Fry, DW; Rubin, JR; Denny, WA	6/6/1997	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3697	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3697&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328349	8033413							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5460	Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)	TWTYLCVLKNHZDT-UHFFFAOYSA-N	3600	4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine::CHEMBL51853::Pyrido[3,4-d]pyrimidine 7b	Epidermal growth factor receptor	Homo sapiens		 0.13					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3600&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328258	8033321		CHEMBL51853					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5461	CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)	KFHMLBXBRCITHF-UHFFFAOYSA-N	3603	4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine::CHEMBL53753::PD158780	Epidermal growth factor receptor	Homo sapiens		 0.008					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3603&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4707	8033324		CHEMBL53753					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5462	CN(C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C15H14BrN5/c1-21(2)14-7-12-13(8-17-14)18-9-19-15(12)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)	QFXMHNZCUIIRHD-UHFFFAOYSA-N	3604	CHEMBL53711::4-[(3-bromophenyl)-amino]-6-(dimethylamino)pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine::Pyrido[3,4-d]pyrimidine 7g	Epidermal growth factor receptor	Homo sapiens		 0.006					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3604&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328261	8033325		CHEMBL53711					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5463	OCCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C15H14BrN5O/c16-10-2-1-3-11(6-10)21-15-12-7-14(17-4-5-22)18-8-13(12)19-9-20-15/h1-3,6-9,22H,4-5H2,(H,17,18)(H,19,20,21)	BSMQFXOOMVGQQY-UHFFFAOYSA-N	3700	4-[(3-Bromophenyl)amino]-6-[(2-hydroxyethyl)amino]-pyrido[3,4-d]pyrimidine::2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)ethan-1-ol::PD158780 Analog 5d	Epidermal growth factor receptor	Homo sapiens		 0.19					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3700	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3700&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328350	8033414							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5464	CN(CCO)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C16H16BrN5O/c1-22(5-6-23)15-8-13-14(9-18-15)19-10-20-16(13)21-12-4-2-3-11(17)7-12/h2-4,7-10,23H,5-6H2,1H3,(H,19,20,21)	FJHAVJDRZOHMAT-UHFFFAOYSA-N	3701	4-[(3-Bromophenyl)amino]-6-[N-(2-hydroxyethyl)-N-methylamino]pyrido[3,4-d]pyrimidine::2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}(methyl)amino)ethan-1-ol::PD158780 Analog 5e	Epidermal growth factor receptor	Homo sapiens		 0.22					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3701&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328351	8033415							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5465	OCC(O)CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C16H16BrN5O2/c17-10-2-1-3-11(4-10)22-16-13-5-15(18-6-12(24)8-23)19-7-14(13)20-9-21-16/h1-5,7,9,12,23-24H,6,8H2,(H,18,19)(H,20,21,22)	OJFNYXBTRFDYPU-UHFFFAOYSA-N	3702	4-[(3-Bromophenyl)amino]-6-[(2,3-dihydroxypropyl)-amino]pyrido[3,4-d]pyrimidine::3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)propane-1,2-diol::PD158780 Analog 5f	Epidermal growth factor receptor	Homo sapiens		 0.18					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3702&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328352	8033416							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5466	CN(CC(O)CO)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C17H18BrN5O2/c1-23(8-13(25)9-24)16-6-14-15(7-19-16)20-10-21-17(14)22-12-4-2-3-11(18)5-12/h2-7,10,13,24-25H,8-9H2,1H3,(H,20,21,22)	QSUNZQDMCQHQDO-UHFFFAOYSA-N	3703	3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}(methyl)amino)propane-1,2-diol::4-[(3-Bromophenyl)amino]-6-[N-(2,3-dihydroxypropyl)-N-methylamino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5g	Epidermal growth factor receptor	Homo sapiens		 0.56					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3703	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3703&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328353	8033417							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5467	CN(C)CCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C17H19BrN6/c1-24(2)7-6-19-16-9-14-15(10-20-16)21-11-22-17(14)23-13-5-3-4-12(18)8-13/h3-5,8-11H,6-7H2,1-2H3,(H,19,20)(H,21,22,23)	RMBTVBFZJFUISC-UHFFFAOYSA-N	3704	4-[(3-Bromophenyl)amino]-6-[[2-(dimethylamino)-ethyl]amino]pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 5h	Epidermal growth factor receptor	Homo sapiens		 1.1					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3704	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3704&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328354	8033418							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5468	CN(C)CCCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C18H21BrN6/c1-25(2)8-4-7-20-17-10-15-16(11-21-17)22-12-23-18(15)24-14-6-3-5-13(19)9-14/h3,5-6,9-12H,4,7-8H2,1-2H3,(H,20,21)(H,22,23,24)	WBGYUVVZVWPMCL-UHFFFAOYSA-N	3705	4-N-(3-bromophenyl)-6-N-[3-(dimethylamino)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Bromophenyl)amino]-6-[[3-(dimethylamino)propyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5i	Epidermal growth factor receptor	Homo sapiens		 1.2					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3705&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328355	8033419							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5469	CN(C)CCCCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C19H23BrN6/c1-26(2)9-4-3-8-21-18-11-16-17(12-22-18)23-13-24-19(16)25-15-7-5-6-14(20)10-15/h5-7,10-13H,3-4,8-9H2,1-2H3,(H,21,22)(H,23,24,25)	HAZMQKHDVTUCEW-UHFFFAOYSA-N	3706	4-[(3-Bromophenyl)amino]-6-[[4-(dimethylamino)butyl]amino]pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N-[4-(dimethylamino)butyl]pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 5j	Epidermal growth factor receptor	Homo sapiens		 1.8					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3706	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3706&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328356	8033420							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5470	CCN(CC)CC(O)CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C20H25BrN6O/c1-3-27(4-2)12-16(28)10-22-19-9-17-18(11-23-19)24-13-25-20(17)26-15-7-5-6-14(21)8-15/h5-9,11,13,16,28H,3-4,10,12H2,1-2H3,(H,22,23)(H,24,25,26)	RNIMVALSZBLGMI-UHFFFAOYSA-N	3707	4-N-(3-bromophenyl)-6-N-[3-(diethylamino)-2-hydroxypropyl]pyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Bromophenyl)amino]-6-[[3-(diethylamino)-2-hydroxypropyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5k	Epidermal growth factor receptor	Homo sapiens		 4.6					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3707	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3707&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328357	8033421							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5471	CN(CCO)CCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C18H21BrN6O/c1-25(7-8-26)6-5-20-17-10-15-16(11-21-17)22-12-23-18(15)24-14-4-2-3-13(19)9-14/h2-4,9-12,26H,5-8H2,1H3,(H,20,21)(H,22,23,24)	APZJVORBGFQNIQ-UHFFFAOYSA-N	3708	2-{[2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)ethyl](methyl)amino}ethan-1-ol::4-[(3-Bromophenyl)amino]-6-[[2-[N-(2-hydroxyethyl)-methylamino]ethyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5l	Epidermal growth factor receptor	Homo sapiens		 1.7					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3708	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3708&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328358	8033422							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5472	CN(C)CCN(C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C18H21BrN6/c1-24(2)7-8-25(3)17-10-15-16(11-20-17)21-12-22-18(15)23-14-6-4-5-13(19)9-14/h4-6,9-12H,7-8H2,1-3H3,(H,21,22,23)	HTUBDSNBHLULPF-UHFFFAOYSA-N	3709	4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Bromophenyl)amino]-6-[N-[2-(dimethylamino)-ethyl]-N-methylamino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5m	Epidermal growth factor receptor	Homo sapiens		 8.1					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3709	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3709&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328359	8033423							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5473	Brc1cccc(Nc2ncnc3cnc(NCCN4CCOCC4)cc23)c1	InChI=1S/C19H21BrN6O/c20-14-2-1-3-15(10-14)25-19-16-11-18(22-12-17(16)23-13-24-19)21-4-5-26-6-8-27-9-7-26/h1-3,10-13H,4-9H2,(H,21,22)(H,23,24,25)	BGPOQKXCTILWFE-UHFFFAOYSA-N	3710	4-N-(3-bromophenyl)-6-N-[2-(morpholin-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Bromophenyl)amino]-6-[[2-(4-morpholino)ethyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5n	Epidermal growth factor receptor	Homo sapiens		 0.65					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3710	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3710&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328360	8033424							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5474	Brc1cccc(Nc2ncnc3cnc(NCCCN4CCOCC4)cc23)c1	InChI=1S/C20H23BrN6O/c21-15-3-1-4-16(11-15)26-20-17-12-19(23-13-18(17)24-14-25-20)22-5-2-6-27-7-9-28-10-8-27/h1,3-4,11-14H,2,5-10H2,(H,22,23)(H,24,25,26)	OJRQYIAKSVOWNZ-UHFFFAOYSA-N	3711	4-N-(3-bromophenyl)-6-N-[3-(morpholin-4-yl)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Bromophenyl)amino]-6-[[3-(4-morpholino)propyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5o	Epidermal growth factor receptor	Homo sapiens		 1.0					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3711	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3711&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328361	8033425							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5475	CN1CCN(CCCNc2cc3c(Nc4cccc(Br)c4)ncnc3cn2)CC1	InChI=1S/C21H26BrN7/c1-28-8-10-29(11-9-28)7-3-6-23-20-13-18-19(14-24-20)25-15-26-21(18)27-17-5-2-4-16(22)12-17/h2,4-5,12-15H,3,6-11H2,1H3,(H,23,24)(H,25,26,27)	KTYKVNHDFASIGH-UHFFFAOYSA-N	3712	4-[(3-Bromophenyl)amino]-6-[[3-(4-methyl-1-piperazinyl)propyl]amino]pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N-[3-(4-methylpiperazin-1-yl)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 5p	Epidermal growth factor receptor	Homo sapiens		 3.9					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3712	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3712&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328362	8033426							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5476	OCCN(CCO)CCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C19H23BrN6O2/c20-14-2-1-3-15(10-14)25-19-16-11-18(22-12-17(16)23-13-24-19)21-4-5-26(6-8-27)7-9-28/h1-3,10-13,27-28H,4-9H2,(H,21,22)(H,23,24,25)	HESSFGACSQOVPK-UHFFFAOYSA-N	3713	4-[(3-Bromophenyl)amino]-6-[[2-[N,N-bis(2-hydroxyethyl)amino]ethyl]amino]pyrido[3,4-d]pyrimidine::2-{[2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)ethyl](2-hydroxyethyl)amino}ethan-1-ol::PD158780 Analog 5q	Epidermal growth factor receptor	Homo sapiens		 0.93					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3713	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3713&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328363	8033427							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5477	OCCN(CCO)CCCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C20H25BrN6O2/c21-15-3-1-4-16(11-15)26-20-17-12-19(23-13-18(17)24-14-25-20)22-5-2-6-27(7-9-28)8-10-29/h1,3-4,11-14,28-29H,2,5-10H2,(H,22,23)(H,24,25,26)	YQPDGPGZDSDTPY-UHFFFAOYSA-N	3714	2-{[3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)propyl](2-hydroxyethyl)amino}ethan-1-ol::4-[(3-Bromophenyl)amino]-6-[[3-[N,N-bis(2-hydroxyethyl)amino]propyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5r	Epidermal growth factor receptor	Homo sapiens		 0.35					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3714	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3714&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328364	8033428							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5478	Brc1cccc(Nc2ncnc3cnc(NCc4cccnc4)cc23)c1	InChI=1S/C19H15BrN6/c20-14-4-1-5-15(7-14)26-19-16-8-18(23-11-17(16)24-12-25-19)22-10-13-3-2-6-21-9-13/h1-9,11-12H,10H2,(H,22,23)(H,24,25,26)	YXYVEDNSDFQKHH-UHFFFAOYSA-N	3715	4-[(3-Bromophenyl)amino]-6-[(3-pyridyl)methylamino]-pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N-(pyridin-3-ylmethyl)pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 5s	Epidermal growth factor receptor	Homo sapiens		 1.5							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3715	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3715&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328365	8033429							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5479	Brc1cccc(Nc2ncnc3cnc(NCCc4ccccn4)cc23)c1	InChI=1S/C20H17BrN6/c21-14-4-3-6-16(10-14)27-20-17-11-19(24-12-18(17)25-13-26-20)23-9-7-15-5-1-2-8-22-15/h1-6,8,10-13H,7,9H2,(H,23,24)(H,25,26,27)	JGLPCRUFWFOQKT-UHFFFAOYSA-N	3716	4-[(3-Bromophenyl)amino]-6-[[2-(2-pyridyl)ethyl]amino]pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N-[2-(pyridin-2-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 5t	Epidermal growth factor receptor	Homo sapiens		 1.2							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3716	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3716&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328366	8033430							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5480	Brc1cccc(Nc2ncnc3cnc(NCCc4cnc[nH]4)cc23)c1	InChI=1S/C18H16BrN7/c19-12-2-1-3-13(6-12)26-18-15-7-17(22-9-16(15)24-11-25-18)21-5-4-14-8-20-10-23-14/h1-3,6-11H,4-5H2,(H,20,23)(H,21,22)(H,24,25,26)	JKSUBOCXWXIPAH-UHFFFAOYSA-N	3717	4-[(3-Bromophenyl)amino]-6-[[2-(4-imidazolyl)ethyl]-amino]pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N-[2-(1H-imidazol-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 5u	Epidermal growth factor receptor	Homo sapiens		 0.78							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3717&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328367	8033431							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5481	Brc1cccc(Nc2ncnc3cnc(NCCCn4ccnc4)cc23)c1	InChI=1S/C19H18BrN7/c20-14-3-1-4-15(9-14)26-19-16-10-18(23-11-17(16)24-12-25-19)22-5-2-7-27-8-6-21-13-27/h1,3-4,6,8-13H,2,5,7H2,(H,22,23)(H,24,25,26)	IUQWETRSDSASNL-UHFFFAOYSA-N	3718	4-[(3-Bromophenyl)amino]-6-[[3-(1-imidazolyl)propyl]-amino]pyrido[3,4-d]pyrimidine::4-N-(3-bromophenyl)-6-N-[3-(1H-imidazol-1-yl)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 5v	Epidermal growth factor receptor	Homo sapiens		 1.7							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3718	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3718&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328368	8033432							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5482	CN1CCN(CC1)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C18H19BrN6/c1-24-5-7-25(8-6-24)17-10-15-16(11-20-17)21-12-22-18(15)23-14-4-2-3-13(19)9-14/h2-4,9-12H,5-8H2,1H3,(H,21,22,23)	FTYUEIQBPIWEPZ-UHFFFAOYSA-N	3719	4-[(3-Bromophenyl)amino]-6-(4-methyl-1-piperazinyl)-pyrido[3,4-d]pyrimidine::N-(3-bromophenyl)-6-(4-methylpiperazin-1-yl)pyrido[3,4-d]pyrimidin-4-amine::PD158780 Analog 5w	Epidermal growth factor receptor	Homo sapiens		 6.4							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3719	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3719&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328369	8033433							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5483	OC(=O)CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C15H12BrN5O2/c16-9-2-1-3-10(4-9)21-15-11-5-13(18-7-14(22)23)17-6-12(11)19-8-20-15/h1-6,8H,7H2,(H,17,18)(H,22,23)(H,19,20,21)	IGLQVXWYTLQQLP-UHFFFAOYSA-N	3720	2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)acetic acid::4-[(3-Bromophenyl)amino]-6-[(carboxymethyl)amino]-pyrido[3,4-d]pyrimidine::PD158780 Analog 5x	Epidermal growth factor receptor	Homo sapiens		 0.28							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3720	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3720&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328370	8033434							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5484	CN(CC(O)=O)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C16H14BrN5O2/c1-22(8-15(23)24)14-6-12-13(7-18-14)19-9-20-16(12)21-11-4-2-3-10(17)5-11/h2-7,9H,8H2,1H3,(H,23,24)(H,19,20,21)	UFGHDYZMVXQBKH-UHFFFAOYSA-N	3721	4-[(3-Bromophenyl)amino]-6-[N-(carboxymethyl)methylamino]pyrido[3,4-d]pyrimidine::2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}(methyl)amino)acetic acid::PD158780 Analog 5y	Epidermal growth factor receptor	Homo sapiens		 0.44							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3721	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3721&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328371	8033435							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5485	OC(=O)CCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C16H14BrN5O2/c17-10-2-1-3-11(6-10)22-16-12-7-14(18-5-4-15(23)24)19-8-13(12)20-9-21-16/h1-3,6-9H,4-5H2,(H,18,19)(H,23,24)(H,20,21,22)	ZKLMDMQVDFQTDL-UHFFFAOYSA-N	3722	3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)propanoic acid::4-[(3-Bromophenyl)amino]-6-[(2-carboxyethyl)amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5z	Epidermal growth factor receptor	Homo sapiens		 0.27							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3722	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3722&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328372	8033436							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5486	CNc1cc2c(Nc3ccccc3)ncnc2cn1	InChI=1S/C14H13N5/c1-15-13-7-11-12(8-16-13)17-9-18-14(11)19-10-5-3-2-4-6-10/h2-9H,1H3,(H,15,16)(H,17,18,19)	VUQQZAQCQFIXAH-UHFFFAOYSA-N	3607	6-N-methyl-4-N-phenylpyrido[3,4-d]pyrimidine-4,6-diamine::CHEMBL53940::6-(Methylamino)-4-(phenylamino)pyrido[3,4-d]pyrimidine::Pyrido[3,4-d]pyrimidine 13f	Epidermal growth factor receptor	Homo sapiens		 9							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3607	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3607&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328264	8033328		CHEMBL53940					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5487	CNc1cc2c(Nc3cccc(Cl)c3)ncnc2cn1	InChI=1S/C14H12ClN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)	KYQINICYADKJGN-UHFFFAOYSA-N	3724	4-N-(3-chlorophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Chlorophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine::PD158780 Analog 7b	Epidermal growth factor receptor	Homo sapiens		 0.19							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3724	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3724&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328373	8033437							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5488	CNc1cc2c(Nc3cccc(c3)C(F)(F)F)ncnc2cn1	InChI=1S/C15H12F3N5/c1-19-13-6-11-12(7-20-13)21-8-22-14(11)23-10-4-2-3-9(5-10)15(16,17)18/h2-8H,1H3,(H,19,20)(H,21,22,23)	DYODBQSUUIBESA-UHFFFAOYSA-N	3725	6-N-methyl-4-N-[3-(trifluoromethyl)phenyl]pyrido[3,4-d]pyrimidine-4,6-diamine::6-(Methylamino)-4-[[3-(trifluoromethyl)phenyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 8b	Epidermal growth factor receptor	Homo sapiens		 1.1							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3725	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3725&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328374	8033438							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5489	Cc1cccc(Nc2ncnc3cnc(N)cc23)c1	InChI=1S/C14H13N5/c1-9-3-2-4-10(5-9)19-14-11-6-13(15)16-7-12(11)17-8-18-14/h2-8H,1H3,(H2,15,16)(H,17,18,19)	VNRZOOJIGRYVTF-UHFFFAOYSA-N	3726	4-N-(3-methylphenyl)pyrido[3,4-d]pyrimidine-4,6-diamine::6-Amino-4-[(3-methylphenyl)amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 9a	Epidermal growth factor receptor	Homo sapiens		 3.1							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3726	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3726&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328375	8033439							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5490	CNc1cc2c(Nc3cccc(C)c3)ncnc2cn1	InChI=1S/C15H15N5/c1-10-4-3-5-11(6-10)20-15-12-7-14(16-2)17-8-13(12)18-9-19-15/h3-9H,1-2H3,(H,16,17)(H,18,19,20)	CCLWZSQAMSFYER-UHFFFAOYSA-N	3727	6-(Methylamino)-4-[(3-methylphenyl)amino]pyrido[3,4-d]pyrimidine::6-N-methyl-4-N-(3-methylphenyl)pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 9b	Epidermal growth factor receptor	Homo sapiens		 0.45							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3727	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3727&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328376	8033440							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5491	CN(C)c1cc2c(Nc3cccc(C)c3)ncnc2cn1	InChI=1S/C16H17N5/c1-11-5-4-6-12(7-11)20-16-13-8-15(21(2)3)17-9-14(13)18-10-19-16/h4-10H,1-3H3,(H,18,19,20)	SSOSNGLIBSWZMG-UHFFFAOYSA-N	3728	6-N,6-N-dimethyl-4-N-(3-methylphenyl)pyrido[3,4-d]pyrimidine-4,6-diamine::6-(Dimethylamino)-4-[(3-methylphenyl)amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 9c	Epidermal growth factor receptor	Homo sapiens		 2.8							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3728	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3728&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328377	8033441							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5492	Cc1cccc(Nc2ncnc3cnc(NCCN4CCOCC4)cc23)c1	InChI=1S/C20H24N6O/c1-15-3-2-4-16(11-15)25-20-17-12-19(22-13-18(17)23-14-24-20)21-5-6-26-7-9-27-10-8-26/h2-4,11-14H,5-10H2,1H3,(H,21,22)(H,23,24,25)	NSTUOVNEBPHBFU-UHFFFAOYSA-N	3729	4-N-(3-methylphenyl)-6-N-[2-(morpholin-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Methylphenyl)amino]-6-[[2-(4-morpholino)ethyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 9n	Epidermal growth factor receptor	Homo sapiens		 1.5							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3729	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3729&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328378	8033442							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5493	Cc1cccc(Nc2ncnc3cnc(NCCCN4CCOCC4)cc23)c1	InChI=1S/C21H26N6O/c1-16-4-2-5-17(12-16)26-21-18-13-20(23-14-19(18)24-15-25-21)22-6-3-7-27-8-10-28-11-9-27/h2,4-5,12-15H,3,6-11H2,1H3,(H,22,23)(H,24,25,26)	BJYJRYMXVLVRPI-UHFFFAOYSA-N	3730	4-[(3-Methylphenyl)amino]-6-[[3-(4-morpholino)propyl]amino]pyrido[3,4-d]pyrimidine::4-N-(3-methylphenyl)-6-N-[3-(morpholin-4-yl)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 9o	Epidermal growth factor receptor	Homo sapiens		 1.8							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3730	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3730&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328379	8033443							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5494	Cc1cccc(Nc2ncnc3cnc(NCCc4cnc[nH]4)cc23)c1	InChI=1S/C19H19N7/c1-13-3-2-4-14(7-13)26-19-16-8-18(22-10-17(16)24-12-25-19)21-6-5-15-9-20-11-23-15/h2-4,7-12H,5-6H2,1H3,(H,20,23)(H,21,22)(H,24,25,26)	HYWSAKRCBCFZNH-UHFFFAOYSA-N	3731	6-N-[2-(1H-imidazol-4-yl)ethyl]-4-N-(3-methylphenyl)pyrido[3,4-d]pyrimidine-4,6-diamine::6-[[2-(4-Imidazolyl)ethyl]amino]-4-[(3-methylphenyl)amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 9u	Epidermal growth factor receptor	Homo sapiens		 1.3							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3731	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3731&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328380	8033444							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5495	Cc1nc(Nc2cccc(Br)c2)c2cc(NCCN3CCOCC3)ncc2n1	InChI=1S/C20H23BrN6O/c1-14-24-18-13-23-19(22-5-6-27-7-9-28-10-8-27)12-17(18)20(25-14)26-16-4-2-3-15(21)11-16/h2-4,11-13H,5-10H2,1H3,(H,22,23)(H,24,25,26)	YKLBZCPQLOXMBM-UHFFFAOYSA-N	3732	4-N-(3-bromophenyl)-2-methyl-6-N-[2-(morpholin-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Bromophenyl)amino]-2-methyl-6-[[2-(4-morpholino)ethyl]amino]pyrido[3,4-d]pyrimidine::PD158780 Analog 10n	Epidermal growth factor receptor	Homo sapiens		 117							Curated from the literature by BindingDB	10.1021/jm970641d	10.7270/Q2DB800T	9513602	aid1795556		Rewcastle, GW; Murray, DK; Elliott, WL; Fry, DW; Howard, CT; Nelson, JM; Roberts, BJ; Vincent, PW; Showalter, HD; Winters, RT; Denny, WA	2/26/1998	3/14/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3732	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3732&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328381	8033445							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5496	Cc1cccc(Nc2cc(NCCO)ncn2)c1	InChI=1S/C13H16N4O/c1-10-3-2-4-11(7-10)17-13-8-12(14-5-6-18)15-9-16-13/h2-4,7-9,18H,5-6H2,1H3,(H2,14,15,16,17)	JUAWTNMXJGPKET-UHFFFAOYSA-N	3733	2-({6-[(3-methylphenyl)amino]pyrimidin-4-yl}amino)ethan-1-ol::Anilinopyrimidine deriv. 1	Epidermal growth factor receptor	Homo sapiens		 1					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3733	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3733&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328382	8033446							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5497	Clc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10ClN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	ZKKVUIPXPPDIRD-UHFFFAOYSA-N	3263	CHEMBL329672::N-(3-chlorophenyl)quinazolin-4-amine::CHEMBL555321::4-Anilino quinazoline deriv. 14	Epidermal growth factor receptor	Homo sapiens		 23					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3263	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3263&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			128872	8033005		CHEMBL555321CHEMBL329672					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5498	Brc1cccc(Nc2ncnc3ccsc23)c1	InChI=1S/C12H8BrN3S/c13-8-2-1-3-9(6-8)16-12-11-10(4-5-17-11)14-7-15-12/h1-7H,(H,14,15,16)	IKDNMRVPNRIVPS-UHFFFAOYSA-N	3735	N-(3-bromophenyl)thieno[3,2-d]pyrimidin-4-amine::Anilinopyrimidine deriv. 3	Epidermal growth factor receptor	Homo sapiens		 11					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3735&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328383	8033447							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5499	Brc1cccc(Nc2ncnc3sccc23)c1	InChI=1S/C12H8BrN3S/c13-8-2-1-3-9(6-8)16-11-10-4-5-17-12(10)15-7-14-11/h1-7H,(H,14,15,16)	WYOFJYXGKWRDKC-UHFFFAOYSA-N	3736	N-(3-bromophenyl)thieno[2,3-d]pyrimidin-4-amine::Anilinopyrimidine deriv. 4	Epidermal growth factor receptor	Homo sapiens		 35					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3736	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3736&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2103474	8033448							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5501	CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)	KFHMLBXBRCITHF-UHFFFAOYSA-N	3603	4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine::CHEMBL53753::PD158780	Epidermal growth factor receptor	Homo sapiens		 0.008					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3603&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4707	8033324		CHEMBL53753					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5502	Brc1cccc(Nc2ncnc3cc4nc[nH]c4cc23)c1	InChI=1S/C15H10BrN5/c16-9-2-1-3-10(4-9)21-15-11-5-13-14(19-7-18-13)6-12(11)17-8-20-15/h1-8H,(H,18,19)(H,17,20,21)	BZHDPIVTQKXAQQ-UHFFFAOYSA-N	3570	N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amine::CHEMBL66031::Anilinopyrimidine deriv. 7a::8-[(3-Bromophenyl)amino]-1H-imidazo[4,5-g]quinazoline::Imidazoquinazoline deriv. 8	Epidermal growth factor receptor	Homo sapiens		 0.008					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3570&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2428	8033293		CHEMBL66031					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5503	Brc1cccc(Nc2ncnc3cc4[nH]ccc4cc23)c1	InChI=1S/C16H11BrN4/c17-11-2-1-3-12(7-11)21-16-13-6-10-4-5-18-14(10)8-15(13)19-9-20-16/h1-9,18H,(H,19,20,21)	BBFWQWIFLDQYQQ-UHFFFAOYSA-N	3583	Pyrroloquinazoline deriv. 3a::Anilinopyrimidine deriv. 7b::5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazoline::N-(3-bromophenyl)-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 21	Epidermal growth factor receptor	Homo sapiens		 0.39					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3583&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328243	8033306							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5504	Brc1cccc(Nc2ncnc3cc4[nH]ncc4cc23)c1	InChI=1S/C15H10BrN5/c16-10-2-1-3-11(5-10)20-15-12-4-9-7-19-21-13(9)6-14(12)17-8-18-15/h1-8H,(H,19,21)(H,17,18,20)	ORCWMSOZENFEDR-UHFFFAOYSA-N	3582	N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-amine::Anilinopyrimidine deriv. 7c::Pyrazoloquinazoline deriv. 2a::5-[(3-Bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazoline::Pyrazoloquinazoline deriv. 20	Epidermal growth factor receptor	Homo sapiens		 0.44					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3582&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328242	8033305							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5505	Brc1cccc(Nc2ncnc3ccc4[nH]cnc4c23)c1	InChI=1S/C15H10BrN5/c16-9-2-1-3-10(6-9)21-15-13-11(17-8-20-15)4-5-12-14(13)19-7-18-12/h1-8H,(H,18,19)(H,17,20,21)	ZCTBHAZSEIICRJ-UHFFFAOYSA-N	3577	9-[(3-Bromophenyl)amino]-1H-imidazo[4,5-f]quinazoline::N-(3-bromophenyl)-3,5,10,12-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,7,10,12-hexaen-13-amine::Anilinopyrimidine deriv. 8a::Imidazoquinazoline deriv. 15	Epidermal growth factor receptor	Homo sapiens		 29					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3577&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328238	8033300							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5506	Brc1cccc(Nc2ncnc3ccc4cc[nH]c4c23)c1	InChI=1S/C16H11BrN4/c17-11-2-1-3-12(8-11)21-16-14-13(19-9-20-16)5-4-10-6-7-18-15(10)14/h1-9,18H,(H,19,20,21)	DRORNTZBMUKMSZ-UHFFFAOYSA-N	3584	N-(3-bromophenyl)-3,10,12-triazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,7,10,12-hexaen-13-amine::Anilinopyrimidine deriv. 8b::9-[(3-Bromophenyl)amino]-1H-pyrrolo[2,3-f]quinazoline::Pyrroloquinazoline deriv. 22	Epidermal growth factor receptor	Homo sapiens		 1.24					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3584&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328244	8033307							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5507	Brc1cccc(Nc2ncnc3c4nc[nH]c4ccc23)c1	InChI=1S/C15H10BrN5/c16-9-2-1-3-10(6-9)21-15-11-4-5-12-14(19-7-17-12)13(11)18-8-20-15/h1-8H,(H,17,19)(H,18,20,21)	NIYBTTXLFLIXIE-UHFFFAOYSA-N	3578	6-[(3-Bromophenyl)amino]-1H-imidazo[4,5-h]quinazoline::N-(3-bromophenyl)-3,5,11,13-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,7,10,12-hexaen-10-amine::Anilinopyrimidine deriv. 9::Imidazoquinazoline deriv. 16	Epidermal growth factor receptor	Homo sapiens		 272					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3578&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328239	8033301							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5508	N(c1ccccc1)c1ncnc2c3ccccc3[nH]c12	InChI=1S/C16H12N4/c1-2-6-11(7-3-1)19-16-15-14(17-10-18-16)12-8-4-5-9-13(12)20-15/h1-10,20H,(H,17,18,19)	OKBOHUBQBRDHRI-UHFFFAOYSA-N	3743	N-phenyl-5H-pyrimido[5,4-b]indol-4-amine::N-Phenyl-5H-pyrimido[5,4-b]indole-4-amine Hydrochloride::Pyrimido[5,4-b]indole deriv. 34	Epidermal growth factor receptor	Homo sapiens		 2110					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3743	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3743&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328384	8033449							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5509	Brc1cccc(Nc2ncnc3c4ccccc4[nH]c23)c1	InChI=1S/C16H11BrN4/c17-10-4-3-5-11(8-10)20-16-15-14(18-9-19-16)12-6-1-2-7-13(12)21-15/h1-9,21H,(H,18,19,20)	MQJJIOLMGNHHTC-UHFFFAOYSA-N	3744	N-(3-bromophenyl)-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 35	Epidermal growth factor receptor	Homo sapiens		 72					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3744	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3744&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328385	8033450							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5510	Cn1c2ccccc2c2ncnc(Nc3cccc(Br)c3)c12	InChI=1S/C17H13BrN4/c1-22-14-8-3-2-7-13(14)15-16(22)17(20-10-19-15)21-12-6-4-5-11(18)9-12/h2-10H,1H3,(H,19,20,21)	ULWYMPIRZLVNFN-UHFFFAOYSA-N	3745	N-(3-bromophenyl)-5-methyl-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 36	Epidermal growth factor receptor	Homo sapiens		 132					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3745	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3745&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328386	8033451							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5511	C(Nc1ncnc2c3ccccc3[nH]c12)c1ccccc1	InChI=1S/C17H14N4/c1-2-6-12(7-3-1)10-18-17-16-15(19-11-20-17)13-8-4-5-9-14(13)21-16/h1-9,11,21H,10H2,(H,18,19,20)	NCQYFKGTEDNHPE-UHFFFAOYSA-N	3746	N-benzyl-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 37	Epidermal growth factor receptor	Homo sapiens		 460					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3746	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3746&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			814517	8033452							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5512	C[C@@H](Nc1ncnc2c3ccccc3[nH]c12)c1ccccc1 |r|	InChI=1S/C18H16N4/c1-12(13-7-3-2-4-8-13)21-18-17-16(19-11-20-18)14-9-5-6-10-15(14)22-17/h2-12,22H,1H3,(H,19,20,21)	LITMWRKODNTXFW-UHFFFAOYSA-N	3747	N-[(1R)-1-phenylethyl]-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 38	Epidermal growth factor receptor	Homo sapiens		 419					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3747&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328387	8033453							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5513	C[C@H](Nc1ncnc2c3ccccc3[nH]c12)c1ccccc1 |r|	InChI=1S/C18H16N4/c1-12(13-7-3-2-4-8-13)21-18-17-16(19-11-20-18)14-9-5-6-10-15(14)22-17/h2-12,22H,1H3,(H,19,20,21)	LITMWRKODNTXFW-UHFFFAOYSA-N	3748	N-[(1S)-1-phenylethyl]-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 39	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3748	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3748&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328388	8033454							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5514	C1CCC(CC1)Nc1ncnc2c3ccccc3[nH]c12	InChI=1S/C16H18N4/c1-2-6-11(7-3-1)19-16-15-14(17-10-18-16)12-8-4-5-9-13(12)20-15/h4-5,8-11,20H,1-3,6-7H2,(H,17,18,19)	SVDCFDHUJJDEPO-UHFFFAOYSA-N	3749	N-cyclohexyl-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 40	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3749	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3749&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328389	8033455							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5515	CN(C)CCNc1ncnc2c3ccccc3[nH]c12	InChI=1S/C14H17N5/c1-19(2)8-7-15-14-13-12(16-9-17-14)10-5-3-4-6-11(10)18-13/h3-6,9,18H,7-8H2,1-2H3,(H,15,16,17)	KZFHGBQJNVSGMS-UHFFFAOYSA-N	3750	dimethyl(2-{5H-pyrimido[5,4-b]indol-4-ylamino}ethyl)amine::Pyrimido[5,4-b]indole deriv. 41	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3750&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			938880	8033456							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5516	CN(C)CCNc1ncnc2[nH]c3ccccc3c12	InChI=1S/C14H17N5/c1-19(2)8-7-15-13-12-10-5-3-4-6-11(10)18-14(12)17-9-16-13/h3-6,9H,7-8H2,1-2H3,(H2,15,16,17,18)	XPZFMMISYLFNHI-UHFFFAOYSA-N	3751	dimethyl(2-{9H-pyrimido[4,5-b]indol-4-ylamino}ethyl)amine::Pyrimido[4,5-b]indole deriv. 42	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3751	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3751&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328390	8033457							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5517	N(c1ccccc1)c1ncnc2[nH]c3ccccc3c12	InChI=1S/C16H12N4/c1-2-6-11(7-3-1)19-15-14-12-8-4-5-9-13(12)20-16(14)18-10-17-15/h1-10H,(H2,17,18,19,20)	RNCCWYOKKBCIPY-UHFFFAOYSA-N	3752	N-phenyl-9H-pyrimido[4,5-b]indol-4-amine::Pyrimido[4,5-b]indole deriv. 43	Epidermal growth factor receptor	Homo sapiens		 264							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3752	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3752&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328391	8033458							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5518	Brc1cccc(Nc2ncnc3[nH]c4ccccc4c23)c1	InChI=1S/C16H11BrN4/c17-10-4-3-5-11(8-10)20-15-14-12-6-1-2-7-13(12)21-16(14)19-9-18-15/h1-9H,(H2,18,19,20,21)	MHRKNNUUCCNFPI-UHFFFAOYSA-N	3753	N-(3-bromophenyl)-9H-pyrimido[4,5-b]indol-4-amine::Pyrimido[4,5-b]indole deriv. 44	Epidermal growth factor receptor	Homo sapiens		 31							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3753	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3753&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328392	8033459							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5519	Cn1c2ccccc2c2c(Nc3cccc(Br)c3)ncnc12	InChI=1S/C17H13BrN4/c1-22-14-8-3-2-7-13(14)15-16(19-10-20-17(15)22)21-12-6-4-5-11(18)9-12/h2-10H,1H3,(H,19,20,21)	CNNGEQBPRIKBIC-UHFFFAOYSA-N	3754	N-(3-bromophenyl)-9-methyl-9H-pyrimido[4,5-b]indol-4-amine::Pyrimido[4,5-b]indole deriv. 45	Epidermal growth factor receptor	Homo sapiens		 742							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3754	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3754&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328393	8033460							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5520	CCN(CC)CCn1c2ccccc2c2c(Nc3cccc(Br)c3)ncnc12	InChI=1S/C22H24BrN5/c1-3-27(4-2)12-13-28-19-11-6-5-10-18(19)20-21(24-15-25-22(20)28)26-17-9-7-8-16(23)14-17/h5-11,14-15H,3-4,12-13H2,1-2H3,(H,24,25,26)	XBYDJMWHBZJNBH-UHFFFAOYSA-N	3755	N-(3-bromophenyl)-9-[2-(diethylamino)ethyl]-9H-pyrimido[4,5-b]indol-4-amine::Pyrimido[4,5-b]indole deriv. 46	Epidermal growth factor receptor	Homo sapiens		 4100							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3755	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3755&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328394	8033461							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5521	Cc1nc(Nc2cccc(Br)c2)c2c(n1)[nH]c1ccccc21	InChI=1S/C17H13BrN4/c1-10-19-16(21-12-6-4-5-11(18)9-12)15-13-7-2-3-8-14(13)22-17(15)20-10/h2-9H,1H3,(H2,19,20,21,22)	SHXYXRGXKBHEBR-UHFFFAOYSA-N	3756	N-(3-bromophenyl)-2-methyl-9H-pyrimido[4,5-b]indol-4-amine::Pyrimido[4,5-b]indole deriv. 47	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3756	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3756&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328395	8033462							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5522	Nc1nc(Nc2cccc(Br)c2)c2c(n1)[nH]c1ccccc21	InChI=1S/C16H12BrN5/c17-9-4-3-5-10(8-9)19-14-13-11-6-1-2-7-12(11)20-15(13)22-16(18)21-14/h1-8H,(H4,18,19,20,21,22)	NOUNTOCKLNSANP-UHFFFAOYSA-N	3757	4-N-(3-bromophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine::Pyrimido[4,5-b]indole deriv. 48	Epidermal growth factor receptor	Homo sapiens		 147							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3757	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3757&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328396	8033463							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5523	COc1ccc2[nH]c3ncnc(Nc4cccc(Br)c4)c3c2c1	InChI=1S/C17H13BrN4O/c1-23-12-5-6-14-13(8-12)15-16(19-9-20-17(15)22-14)21-11-4-2-3-10(18)7-11/h2-9H,1H3,(H2,19,20,21,22)	CGDCJUNSPFHRTH-UHFFFAOYSA-N	3758	N-(3-Bromophenyl)-6-methoxy-1H-pyrimido[4,5-b]indole-4-amine::N-(3-bromophenyl)-6-methoxy-9H-pyrimido[4,5-b]indol-4-amine::Pyrimido[4,5-b]indole deriv. 49	Epidermal growth factor receptor	Homo sapiens		 1.2							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3758	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3758&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328397	8033464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5524	CCN(CC)CCn1c2ccc(OC)cc2c2c(Nc3cccc(Br)c3)ncnc12	InChI=1S/C23H26BrN5O/c1-4-28(5-2)11-12-29-20-10-9-18(30-3)14-19(20)21-22(25-15-26-23(21)29)27-17-8-6-7-16(24)13-17/h6-10,13-15H,4-5,11-12H2,1-3H3,(H,25,26,27)	KGOOHLRXQJDOJF-UHFFFAOYSA-N	3759	N-(3-bromophenyl)-9-[2-(diethylamino)ethyl]-6-methoxy-9H-pyrimido[4,5-b]indol-4-amine::Pyrimido[4,5-b]indole deriv. 50	Epidermal growth factor receptor	Homo sapiens		 4270							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3759	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3759&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328398	8033465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5525	C(Nc1ncnc2c3ccccc3sc12)c1ccccc1	InChI=1S/C17H13N3S/c1-2-6-12(7-3-1)10-18-17-16-15(19-11-20-17)13-8-4-5-9-14(13)21-16/h1-9,11H,10H2,(H,18,19,20)	XJRQKMJYHWKOOV-UHFFFAOYSA-N	3760	N-benzyl-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 51	Epidermal growth factor receptor	Homo sapiens		 191							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3760	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3760&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328399	8033466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5526	C[C@@H](Nc1ncnc2c3ccccc3sc12)c1ccccc1 |r|	InChI=1S/C18H15N3S/c1-12(13-7-3-2-4-8-13)21-18-17-16(19-11-20-18)14-9-5-6-10-15(14)22-17/h2-12H,1H3,(H,19,20,21)	WXXYNGFRGPWDFC-UHFFFAOYSA-N	3761	N-[(1R)-1-phenylethyl]-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::CHEMBL103014::Benzothieno[3,2-d]pyrimidine deriv. 52	Epidermal growth factor receptor	Homo sapiens		 538							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3761	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3761&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328400	8033467		CHEMBL103014					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5527	Brc1cccc(Nc2ncnc3c4ccccc4sc23)c1	InChI=1S/C16H10BrN3S/c17-10-4-3-5-11(8-10)20-16-15-14(18-9-19-16)12-6-1-2-7-13(12)21-15/h1-9H,(H,18,19,20)	FNWRJIWVXKOMHC-UHFFFAOYSA-N	3762	N-(3-bromophenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 53	Epidermal growth factor receptor	Homo sapiens		 1.8							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3762	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3762&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328401	8033468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5528	[O-][N+](=O)c1ccc2sc3c(Nc4ccccc4)ncnc3c2c1	InChI=1S/C16H10N4O2S/c21-20(22)11-6-7-13-12(8-11)14-15(23-13)16(18-9-17-14)19-10-4-2-1-3-5-10/h1-9H,(H,17,18,19)	NOBQECCESYXWPW-UHFFFAOYSA-N	3763	4-anilino-8-nitrobenzo[b]thieno[3,2-d]pyrimidine::12-nitro-N-phenyl-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 54	Epidermal growth factor receptor	Homo sapiens		 58							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3763	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3763&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328402	8033469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5529	Cc1cccc(Nc2ncnc3c2sc2ccc(cc32)[N+]([O-])=O)c1	InChI=1S/C17H12N4O2S/c1-10-3-2-4-11(7-10)20-17-16-15(18-9-19-17)13-8-12(21(22)23)5-6-14(13)24-16/h2-9H,1H3,(H,18,19,20)	VRACYLKRFFVNRG-UHFFFAOYSA-N	3764	N-(3-methylphenyl)-12-nitro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 55	Epidermal growth factor receptor	Homo sapiens		 11							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3764&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328403	8033470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5530	[O-][N+](=O)c1ccc2sc3c(Nc4cccc(c4)C(F)(F)F)ncnc3c2c1	InChI=1S/C17H9F3N4O2S/c18-17(19,20)9-2-1-3-10(6-9)23-16-15-14(21-8-22-16)12-7-11(24(25)26)4-5-13(12)27-15/h1-8H,(H,21,22,23)	XUMLPLGHKIPVJA-UHFFFAOYSA-N	3765	12-nitro-N-[3-(trifluoromethyl)phenyl]-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 56	Epidermal growth factor receptor	Homo sapiens		 460							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3765	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3765&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328404	8033471							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5531	[O-][N+](=O)c1ccc2sc3c(Nc4cccc(Br)c4)ncnc3c2c1	InChI=1S/C16H9BrN4O2S/c17-9-2-1-3-10(6-9)20-16-15-14(18-8-19-16)12-7-11(21(22)23)4-5-13(12)24-15/h1-8H,(H,18,19,20)	WETDBUJWZMYYBC-UHFFFAOYSA-N	3766	N-(3-bromophenyl)-12-nitro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 57	Epidermal growth factor receptor	Homo sapiens		 12.3							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3766&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328405	8033472							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5532	Nc1ccc2sc3c(Nc4ccccc4)ncnc3c2c1	InChI=1S/C16H12N4S/c17-10-6-7-13-12(8-10)14-15(21-13)16(19-9-18-14)20-11-4-2-1-3-5-11/h1-9H,17H2,(H,18,19,20)	ZRSXJSKLDBKPLV-UHFFFAOYSA-N	3767	6-N-phenyl-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine::8-Amino-4-anilinobenzo[b]thieno[3,2-d]pyrimidine::Benzothieno[3,2-d]pyrimidine deriv. 58	Epidermal growth factor receptor	Homo sapiens		 9.4							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3767	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3767&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328406	8033473							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5533	Cc1cccc(Nc2ncnc3c4cc(N)ccc4sc23)c1	InChI=1S/C17H14N4S/c1-10-3-2-4-12(7-10)21-17-16-15(19-9-20-17)13-8-11(18)5-6-14(13)22-16/h2-9H,18H2,1H3,(H,19,20,21)	OIFDROVQDZHYPF-UHFFFAOYSA-N	3768	6-N-(3-methylphenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine::Benzothieno[3,2-d]pyrimidine deriv. 59	Epidermal growth factor receptor	Homo sapiens		 2.1							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3768	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3768&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328407	8033474							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5534	Nc1ccc2sc3c(Nc4cccc(c4)C(F)(F)F)ncnc3c2c1	InChI=1S/C17H11F3N4S/c18-17(19,20)9-2-1-3-11(6-9)24-16-15-14(22-8-23-16)12-7-10(21)4-5-13(12)25-15/h1-8H,21H2,(H,22,23,24)	INSDTUVLNWKIRF-UHFFFAOYSA-N	3769	6-N-[3-(trifluoromethyl)phenyl]-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine::Benzothieno[3,2-d]pyrimidine deriv. 60	Epidermal growth factor receptor	Homo sapiens		 47							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3769	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3769&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328408	8033475							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5535	Nc1ccc2sc3c(Nc4cccc(Br)c4)ncnc3c2c1	InChI=1S/C16H11BrN4S/c17-9-2-1-3-11(6-9)21-16-15-14(19-8-20-16)12-7-10(18)4-5-13(12)22-15/h1-8H,18H2,(H,19,20,21)	MEIUULSQALVLOO-UHFFFAOYSA-N	3770	6-N-(3-bromophenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine::Benzothieno[3,2-d]pyrimidine deriv. 61	Epidermal growth factor receptor	Homo sapiens		 0.27							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3770&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328409	8033476							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5536	[O-][N+](=O)c1ccc2c(c1)sc1c(Nc3cccc(Br)c3)ncnc21	InChI=1S/C16H9BrN4O2S/c17-9-2-1-3-10(6-9)20-16-15-14(18-8-19-16)12-5-4-11(21(22)23)7-13(12)24-15/h1-8H,(H,18,19,20)	PJELGIDEIWAUCE-UHFFFAOYSA-N	3771	N-(3-bromophenyl)-11-nitro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 62	Epidermal growth factor receptor	Homo sapiens		 48							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3771	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3771&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328410	8033477							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5537	Nc1ccc2c(c1)sc1c(Nc3cccc(Br)c3)ncnc21	InChI=1S/C16H11BrN4S/c17-9-2-1-3-11(6-9)21-16-15-14(19-8-20-16)12-5-4-10(18)7-13(12)22-15/h1-8H,18H2,(H,19,20,21)	VTCCFNSRHBUEKC-UHFFFAOYSA-N	3772	6-N-(3-bromophenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,11-diamine::Benzothieno[3,2-d]pyrimidine deriv. 63	Epidermal growth factor receptor	Homo sapiens		 0.47							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3772&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328411	8033478							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5538	Nc1cc2sc3c(Nc4cccc(Br)c4)ncnc3c2cc1F	InChI=1S/C16H10BrFN4S/c17-8-2-1-3-9(4-8)22-16-15-14(20-7-21-16)10-5-11(18)12(19)6-13(10)23-15/h1-7H,19H2,(H,20,21,22)	GYZDLQGLTSJPMG-UHFFFAOYSA-N	3773	6-N-(3-bromophenyl)-12-fluoro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,11-diamine::7-Amino-4-(3-bromoanilino)-8-fluorobenzo[b]thieno-[3,2-d]pyrimidine::Benzothieno[3,2-d]pyrimidine deriv. 64	Epidermal growth factor receptor	Homo sapiens		 1.0							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328412	8033479							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5539	CCNc1cc2sc3c(Nc4cccc(Br)c4)ncnc3c2cc1F	InChI=1S/C18H14BrFN4S/c1-2-21-14-8-15-12(7-13(14)20)16-17(25-15)18(23-9-22-16)24-11-5-3-4-10(19)6-11/h3-9,21H,2H2,1H3,(H,22,23,24)	JQKNNKZQNBHDRC-UHFFFAOYSA-N	3774	6-N-(3-bromophenyl)-11-N-ethyl-12-fluoro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,11-diamine::Benzothieno[3,2-d]pyrimidine deriv. 65	Epidermal growth factor receptor	Homo sapiens		 7.9							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3774&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328413	8033480							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5540	COc1ccc2c(c1)sc1c(Nc3cccc(Br)c3)ncnc21	InChI=1S/C17H12BrN3OS/c1-22-12-5-6-13-14(8-12)23-16-15(13)19-9-20-17(16)21-11-4-2-3-10(18)7-11/h2-9H,1H3,(H,19,20,21)	JXAMULRNCBZFDI-UHFFFAOYSA-N	3775	N-(3-bromophenyl)-11-methoxy-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 66	Epidermal growth factor receptor	Homo sapiens		 80							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3775	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3775&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328414	8033481							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5541	CNc1ccc2sc3c(Nc4cccc(Br)c4)ncnc3c2c1	InChI=1S/C17H13BrN4S/c1-19-11-5-6-14-13(8-11)15-16(23-14)17(21-9-20-15)22-12-4-2-3-10(18)7-12/h2-9,19H,1H3,(H,20,21,22)	NRNGTBQZEILVIB-UHFFFAOYSA-N	3776	6-N-(3-bromophenyl)-12-N-methyl-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine::4-(3-Bromoanilino)-8-methylaminobenzo[b]thieno[3,2-d]pyrimidine::Benzothieno[3,2-d]pyrimidine deriv. 67	Epidermal growth factor receptor	Homo sapiens		 1.1							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3776	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3776&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328415	8033482							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5542	CN(C)c1ccc2sc3c(Nc4cccc(Br)c4)ncnc3c2c1	InChI=1S/C18H15BrN4S/c1-23(2)13-6-7-15-14(9-13)16-17(24-15)18(21-10-20-16)22-12-5-3-4-11(19)8-12/h3-10H,1-2H3,(H,20,21,22)	VCEGHIUOGKKYHY-UHFFFAOYSA-N	3777	6-N-(3-bromophenyl)-12-N,12-N-dimethyl-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine::4-(3-Bromoanilino)-8-dimethylaminobenzo[b]thieno[3,2-d]pyrimidine::Benzothieno[3,2-d]pyrimidine deriv. 68	Epidermal growth factor receptor	Homo sapiens		 19.8							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3777&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328416	8033483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5543	COc1cccc2c3ncnc(Nc4cccc(Br)c4)c3sc12	InChI=1S/C17H12BrN3OS/c1-22-13-7-3-6-12-14-16(23-15(12)13)17(20-9-19-14)21-11-5-2-4-10(18)8-11/h2-9H,1H3,(H,19,20,21)	DGYOMIMWPKEDOQ-UHFFFAOYSA-N	3778	N-(3-bromophenyl)-10-methoxy-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 69	Epidermal growth factor receptor	Homo sapiens		 12.6							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3778	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3778&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328417	8033484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5544	[O-][N+](=O)c1cccc2c1sc1c(Nc3cccc(Br)c3)ncnc21	InChI=1S/C16H9BrN4O2S/c17-9-3-1-4-10(7-9)20-16-15-13(18-8-19-16)11-5-2-6-12(21(22)23)14(11)24-15/h1-8H,(H,18,19,20)	CHSSRCXGDCYIHR-UHFFFAOYSA-N	3779	N-(3-bromophenyl)-10-nitro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 70	Epidermal growth factor receptor	Homo sapiens		 158							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3779	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328418	8033485							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5545	Nc1cccc2c1sc1c(Nc3cccc(Br)c3)ncnc21	InChI=1S/C16H11BrN4S/c17-9-3-1-4-10(7-9)21-16-15-13(19-8-20-16)11-5-2-6-12(18)14(11)22-15/h1-8H,18H2,(H,19,20,21)	NPDZHTFXBRQGLG-UHFFFAOYSA-N	3780	6-N-(3-bromophenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,10-diamine::Benzothieno[3,2-d]pyrimidine deriv. 71	Epidermal growth factor receptor	Homo sapiens		 2.7							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3780&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328419	8033486							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5546	COc1cccc2sc3c(Nc4cccc(Br)c4)ncnc3c12	InChI=1S/C17H12BrN3OS/c1-22-12-6-3-7-13-14(12)15-16(23-13)17(20-9-19-15)21-11-5-2-4-10(18)8-11/h2-9H,1H3,(H,19,20,21)	JOSIZTUFKBPVNZ-UHFFFAOYSA-N	3781	N-(3-bromophenyl)-13-methoxy-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 72	Epidermal growth factor receptor	Homo sapiens		 20							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3781	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3781&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328420	8033487							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5547	COc1cc2sc3c(Nc4cccc(Br)c4)ncnc3c2cc1OC	InChI=1S/C18H14BrN3O2S/c1-23-13-7-12-15(8-14(13)24-2)25-17-16(12)20-9-21-18(17)22-11-5-3-4-10(19)6-11/h3-9H,1-2H3,(H,20,21,22)	BQRQLVIVDZZXTA-UHFFFAOYSA-N	3782	N-(3-bromophenyl)-11,12-dimethoxy-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 73	Epidermal growth factor receptor	Homo sapiens		 444							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3782	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3782&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328421	8033488							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5548	Clc1cccc(Nc2ncnc3c4cccnc4sc23)c1	InChI=1S/C15H9ClN4S/c16-9-3-1-4-10(7-9)20-14-13-12(18-8-19-14)11-5-2-6-17-15(11)21-13/h1-8H,(H,18,19,20)	LRYUYVGCKNONRJ-UHFFFAOYSA-N	3783	N-(3-chlorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Pyridothieno[3,2-d]pyrimidine deriv. 74	Epidermal growth factor receptor	Homo sapiens		>1000							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3783&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328422	8033489							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5549	Brc1cccc(Nc2ncnc3c4cccnc4sc23)c1	InChI=1S/C15H9BrN4S/c16-9-3-1-4-10(7-9)20-14-13-12(18-8-19-14)11-5-2-6-17-15(11)21-13/h1-8H,(H,18,19,20)	ZGFNQDIBQOZEFU-UHFFFAOYSA-N	3784	N-(3-bromophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Pyridothieno[3,2-d]pyrimidine deriv. 75	Epidermal growth factor receptor	Homo sapiens		 732							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3784&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328423	8033490							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5550	Brc1cccc(Nc2ncnc3c2sc2ncsc32)c1	InChI=1S/C13H7BrN4S2/c14-7-2-1-3-8(4-7)18-12-10-9(15-5-16-12)11-13(20-10)17-6-19-11/h1-6H,(H,15,16,18)	RLAGSKIPOCVMQK-UHFFFAOYSA-N	3785	N-(3-bromophenyl)-3,7-dithia-5,10,12-triazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),4,9,11-pentaen-9-amine::Thiazolothieno[3,2-d]pyrimidine deriv. 76	Epidermal growth factor receptor	Homo sapiens		 40							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3785&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328424	8033491							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5551	Brc1cccc(Nc2ncnc3c4ccccc4oc23)c1	InChI=1S/C16H10BrN3O/c17-10-4-3-5-11(8-10)20-16-15-14(18-9-19-16)12-6-1-2-7-13(12)21-15/h1-9H,(H,18,19,20)	IBILPMVWJIFCOY-UHFFFAOYSA-N	3786	N-(3-bromophenyl)-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzofurano[3,2-d]pyrimidine deriv. 77	Epidermal growth factor receptor	Homo sapiens		 740							Curated from the literature by BindingDB	10.1021/jm9903949	10.7270/Q28K7783	10639288	aid1795558		Showalter, HD; Bridges, AJ; Zhou, H; Sercel, AD; McMichael, A; Fry, DW	12/30/1999	3/14/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3786&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328425	8033492							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5891	OC(=O)CC1C(=S)Nc2ccccc12	InChI=1S/C10H9NO2S/c12-9(13)5-7-6-3-1-2-4-8(6)11-10(7)14/h1-4,7H,5H2,(H,11,14)(H,12,13)	KTIODNZPIYCZSR-UHFFFAOYSA-N	3956	2-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)acetic acid::(2-thioxo-2,3-dihydro-1H-indol-3-yl)acetic acid::2-thioxo-1H-indole-3-alkanoic acid deriv. 5	Epidermal growth factor receptor	Homo sapiens		 14900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3956&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328535	8033653							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5892	CN1C(=S)C(CC(O)=O)c2ccccc12	InChI=1S/C11H11NO2S/c1-12-9-5-3-2-4-7(9)8(11(12)15)6-10(13)14/h2-5,8H,6H2,1H3,(H,13,14)	MGQMNRPORBTSDW-UHFFFAOYSA-N	3957	2-(1-methyl-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)acetic acid::2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-acetic Acid::2-thioxo-1H-indole-3-alkanoic acid deriv. 6	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3957&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328536	8033654							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5893	COC(=O)CC1C(=S)Nc2ccccc12	InChI=1S/C11H11NO2S/c1-14-10(13)6-8-7-4-2-3-5-9(7)12-11(8)15/h2-5,8H,6H2,1H3,(H,12,15)	HSUWGLPKYSSVBN-UHFFFAOYSA-N	3958	methyl 2-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)acetate::Methyl 2,3-Dihydro-2-thioxo-1H-indole-3-acetate::2-thioxo-1H-indole-3-alkanoic acid deriv. 7	Epidermal growth factor receptor	Homo sapiens		 100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3958	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3958&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328537	8033655							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5894	COC(=O)CC1C(=S)N(C)c2ccccc12	InChI=1S/C12H13NO2S/c1-13-10-6-4-3-5-8(10)9(12(13)16)7-11(14)15-2/h3-6,9H,7H2,1-2H3	ATODTYDJXOAVQA-UHFFFAOYSA-N	3959	methyl 2-(1-methyl-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)acetate::Methyl 2,3-Dihydro-l-methyl-2-thioxo-1H-indole-3-acetate::2-thioxo-1H-indole-3-alkanoic acid deriv. 8	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3959&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328538	8033656							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5895	OC(=O)CCC1C(=S)Nc2ccccc12	InChI=1S/C11H11NO2S/c13-10(14)6-5-8-7-3-1-2-4-9(7)12-11(8)15/h1-4,8H,5-6H2,(H,12,15)(H,13,14)	XZFPVQIMSWHDCR-UHFFFAOYSA-N	3960	3-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)propanoic acid::2,3-Dihydro-2-thioxo-1H-indole-3-propanoic Acid::2-thioxo-1H-indole-3-alkanoic acid deriv. 9	Epidermal growth factor receptor	Homo sapiens		 1620					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3960&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328539	8033657							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5896	CN1C(=S)C(CCC(O)=O)c2ccccc12	InChI=1S/C12H13NO2S/c1-13-10-5-3-2-4-8(10)9(12(13)16)6-7-11(14)15/h2-5,9H,6-7H2,1H3,(H,14,15)	LBALNCFWTZTSFW-UHFFFAOYSA-N	3961	3-(1-methyl-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)propanoic acid::2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-propanoic Acid::2-thioxo-1H-indole-3-alkanoic acid deriv. 10	Epidermal growth factor receptor	Homo sapiens		 6700					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3961&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328540	8033658							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5897	COC(=O)CCC1C(=S)Nc2ccccc12	InChI=1S/C12H13NO2S/c1-15-11(14)7-6-9-8-4-2-3-5-10(8)13-12(9)16/h2-5,9H,6-7H2,1H3,(H,13,16)	UXBYTLHRGMUZFT-UHFFFAOYSA-N	3962	Methyl 2,3-Dihydro-2-thioxo-1H-indole-3-propanoate::methyl 3-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)propanoate::2-thioxo-1H-indole-3-alkanoic acid deriv. 11	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3962&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328541	8033659							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5898	COC(=O)CCC1C(=S)N(C)c2ccccc12	InChI=1S/C13H15NO2S/c1-14-11-6-4-3-5-9(11)10(13(14)17)7-8-12(15)16-2/h3-6,10H,7-8H2,1-2H3	XUVRAMTZZUYTTG-UHFFFAOYSA-N	3963	Methyl 2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-propanoate::methyl 3-(1-methyl-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)propanoate::2-thioxo-1H-indole-3-alkanoic acid deriv. 12	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3963	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3963&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328542	8033660							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5899	OC(=O)CCCC1C(=S)Nc2ccccc12	InChI=1S/C12H13NO2S/c14-11(15)7-3-5-9-8-4-1-2-6-10(8)13-12(9)16/h1-2,4,6,9H,3,5,7H2,(H,13,16)(H,14,15)	OKZLZNFBUWVBMP-UHFFFAOYSA-N	3964	2,3-Dihydro-2-thioxo-1H-indole-3-butanoic Acid::4-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)butanoic acid::2-thioxo-1H-indole-3-alkanoic acid deriv. 13	Epidermal growth factor receptor	Homo sapiens		 6700					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3964&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328543	8033661							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5900	CN1C(=S)C(CCCC(O)=O)c2ccccc12	InChI=1S/C13H15NO2S/c1-14-11-7-3-2-5-9(11)10(13(14)17)6-4-8-12(15)16/h2-3,5,7,10H,4,6,8H2,1H3,(H,15,16)	QHJCJUXULVYEKC-UHFFFAOYSA-N	3965	4-(1-methyl-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)butanoic acid::2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-butanoic Acid::2-thioxo-1H-indole-3-alkanoic acid deriv. 14	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3965&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328544	8033662							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5901	COC(=O)CCCC1C(=S)Nc2ccccc12	InChI=1S/C13H15NO2S/c1-16-12(15)8-4-6-10-9-5-2-3-7-11(9)14-13(10)17/h2-3,5,7,10H,4,6,8H2,1H3,(H,14,17)	BEJWMUKDOQNVDX-UHFFFAOYSA-N	3966	Methyl 2,3-Dihydro-2-thioxo-1H-indole-3-butanoate::methyl 4-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)butanoate::2-thioxo-1H-indole-3-alkanoic acid deriv. 15	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3966&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328545	8033663							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5902	COC(=O)CCCC1C(=S)N(C)c2ccccc12	InChI=1S/C14H17NO2S/c1-15-12-8-4-3-6-10(12)11(14(15)18)7-5-9-13(16)17-2/h3-4,6,8,11H,5,7,9H2,1-2H3	ZPVGVRHNQYXYDD-UHFFFAOYSA-N	3967	methyl 4-(1-methyl-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)butanoate::Methyl 2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-butanoate::2-thioxo-1H-indole-3-alkanoic acid deriv. 16	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3967	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3967&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328546	8033664							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5903	OC(=O)CCC1(CCC(O)=O)C(=S)Nc2ccccc12	InChI=1S/C14H15NO4S/c16-11(17)5-7-14(8-6-12(18)19)9-3-1-2-4-10(9)15-13(14)20/h1-4H,5-8H2,(H,15,20)(H,16,17)(H,18,19)	IJOAKLSOTLZPAD-UHFFFAOYSA-N	3968	3-[3-(2-carboxyethyl)-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl]propanoic acid::2-thioxo-1H-indole-3-alkanoic acid deriv. 17	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3968&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328547	8033665							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5904	COC(=O)CCC1(CCC(=O)OC)C(=S)Nc2ccccc12	InChI=1S/C16H19NO4S/c1-20-13(18)7-9-16(10-8-14(19)21-2)11-5-3-4-6-12(11)17-15(16)22/h3-6H,7-10H2,1-2H3,(H,17,22)	HIYGHVDHPBJOJY-UHFFFAOYSA-N	3969	methyl 3-[3-(3-methoxy-3-oxopropyl)-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl]propanoate::Dimethyl 1,2-dihydro-2-thioxo-3H-indole-3,3-dipropanoate::2-thioxo-1H-indole-3-alkanoic acid deriv. 18	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3969	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3969&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328548	8033666							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5905	COC(=O)CCN1C(=S)C(CCC(=O)OC)(CCC(=O)OC)c2ccccc12	InChI=1S/C20H25NO6S/c1-25-16(22)8-11-20(12-9-17(23)26-2)14-6-4-5-7-15(14)21(19(20)28)13-10-18(24)27-3/h4-7H,8-13H2,1-3H3	GJMGVLXXCHTSIG-UHFFFAOYSA-N	3970	methyl 3-[1,3-bis(3-methoxy-3-oxopropyl)-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl]propanoate::Trimethyl 1,2-Dihydro-2-thioxo-1H-indole-1,3,3-tripropanoate::2-thioxo-1H-indole-3-alkanoic acid deriv. 19	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3970&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328549	8033667							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5906	OC(=O)Cc1c(SSc2[nH]c3ccccc3c2CC(O)=O)[nH]c2ccccc12	InChI=1S/C20H16N2O4S2/c23-17(24)9-13-11-5-1-3-7-15(11)21-19(13)27-28-20-14(10-18(25)26)12-6-2-4-8-16(12)22-20/h1-8,21-22H,9-10H2,(H,23,24)(H,25,26)	WYVCKDYGPDDNFV-UHFFFAOYSA-N	3971	2,2 -Dithiobis(1H-indole-3-acetic acid)::2-(2-{[3-(carboxymethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)acetic acid::dithiobis(1H-indole-3-alkanoic acid) deriv. 20	Epidermal growth factor receptor	Homo sapiens		 10200					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3971	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3971&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328550	8033668					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5907	Cn1c(SSc2c(CC(O)=O)c3ccccc3n2C)c(CC(O)=O)c2ccccc12	InChI=1S/C22H20N2O4S2/c1-23-17-9-5-3-7-13(17)15(11-19(25)26)21(23)29-30-22-16(12-20(27)28)14-8-4-6-10-18(14)24(22)2/h3-10H,11-12H2,1-2H3,(H,25,26)(H,27,28)	QWGHOVCDGWDKON-UHFFFAOYSA-N	3972	2-(2-{[3-(carboxymethyl)-1-methyl-1H-indol-2-yl]disulfanyl}-1-methyl-1H-indol-3-yl)acetic acid::2,2 -Dithiobis(1-methyl-1H-indole-3-acetic acid)::dithiobis(1H-indole-3-alkanoic acid) deriv. 21	Epidermal growth factor receptor	Homo sapiens		 53000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3972&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328551	8033669					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5908	Oc1ccc(O)c(\C=C\NC=O)c1	InChI=1S/C9H9NO3/c11-6-10-4-3-7-5-8(12)1-2-9(7)13/h1-6,12-13H,(H,10,11)	SIHZWGODIRRSRA-UHFFFAOYSA-N	3973	N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide::cid_58035::erbstatin	Epidermal growth factor receptor	Homo sapiens		 2000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3973	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3973&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328552	8033670					C06049		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5909	COC(=O)Cc1c(SSc2[nH]c3ccccc3c2CC(=O)OC)[nH]c2ccccc12	InChI=1S/C22H20N2O4S2/c1-27-19(25)11-15-13-7-3-5-9-17(13)23-21(15)29-30-22-16(12-20(26)28-2)14-8-4-6-10-18(14)24-22/h3-10,23-24H,11-12H2,1-2H3	ZTGBJDCFDDCDSR-UHFFFAOYSA-N	3974	methyl 2-(2-{[3-(2-methoxy-2-oxoethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)acetate::Dimethyl 2,2 -Dithiobis(1H-indole-3-acetate)::dithiobis(1H-indole-3-alkanoic acid) deriv. 22	Epidermal growth factor receptor	Homo sapiens		 18000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3974	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3974&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328553	8033671					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5910	COC(=O)Cc1c(SSc2c(CC(=O)OC)c3ccccc3n2C)n(C)c2ccccc12	InChI=1S/C24H24N2O4S2/c1-25-19-11-7-5-9-15(19)17(13-21(27)29-3)23(25)31-32-24-18(14-22(28)30-4)16-10-6-8-12-20(16)26(24)2/h5-12H,13-14H2,1-4H3	VKAVZECRLVSBOG-UHFFFAOYSA-N	3975	Dimethyl 2,2 -Dithiobis(1-methyl-1H-indole-3-acetate)::methyl 2-(2-{[3-(2-methoxy-2-oxoethyl)-1-methyl-1H-indol-2-yl]disulfanyl}-1-methyl-1H-indol-3-yl)acetate::dithiobis(1H-indole-3-alkanoic acid) deriv. 23	Epidermal growth factor receptor	Homo sapiens		 33000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3975	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3975&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328554	8033672					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5911	COC(=O)Cc1c(Sc2c(CC(=O)OC)c3ccccc3n2C)n(C)c2ccccc12	InChI=1S/C24H24N2O4S/c1-25-19-11-7-5-9-15(19)17(13-21(27)29-3)23(25)31-24-18(14-22(28)30-4)16-10-6-8-12-20(16)26(24)2/h5-12H,13-14H2,1-4H3	CMDIHELBUWPKKZ-UHFFFAOYSA-N	3976	Dimethyl 2,2 -Thiobis(1-methyl-1H-indole-3-acetate)::methyl 2-(2-{[3-(2-methoxy-2-oxoethyl)-1-methyl-1H-indol-2-yl]sulfanyl}-1-methyl-1H-indol-3-yl)acetate::dithiobis(1H-indole-3-alkanoic acid) deriv. 24	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3976	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3976&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328555	8033673							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5912	OC(=O)Cc1c(SSSc2[nH]c3ccccc3c2CC(O)=O)[nH]c2ccccc12	InChI=1S/C20H16N2O4S3/c23-17(24)9-13-11-5-1-3-7-15(11)21-19(13)27-29-28-20-14(10-18(25)26)12-6-2-4-8-16(12)22-20/h1-8,21-22H,9-10H2,(H,23,24)(H,25,26)	LYVWHGOHXVDLCI-UHFFFAOYSA-N	3977	2,2 -Trithiobis( 1H-indole-3-acetic acid)::2-[2-({[3-(carboxymethyl)-1H-indol-2-yl]sulfanyl}disulfanyl)-1H-indol-3-yl]acetic acid::dithiobis(1H-indole-3-alkanoic acid) deriv. 25	Epidermal growth factor receptor	Homo sapiens		 9300							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3977	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3977&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328556	8033674					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5913	COC(=O)Cc1c(SSSc2[nH]c3ccccc3c2CC(=O)OC)[nH]c2ccccc12	InChI=1S/C22H20N2O4S3/c1-27-19(25)11-15-13-7-3-5-9-17(13)23-21(15)29-31-30-22-16(12-20(26)28-2)14-8-4-6-10-18(14)24-22/h3-10,23-24H,11-12H2,1-2H3	HQPKCMPXXDIADR-UHFFFAOYSA-N	3978	Dimethyl 2,2 -Trithiobis(1H-indole-3-acetate)::methyl 2-[2-({[3-(2-methoxy-2-oxoethyl)-1H-indol-2-yl]sulfanyl}disulfanyl)-1H-indol-3-yl]acetate::dithiobis(1H-indole-3-alkanoic acid) deriv. 26	Epidermal growth factor receptor	Homo sapiens		 35000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3978	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3978&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328557	8033675					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5914	OC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(O)=O)[nH]c2ccccc12	InChI=1S/C22H20N2O4S2/c25-19(26)11-9-15-13-5-1-3-7-17(13)23-21(15)29-30-22-16(10-12-20(27)28)14-6-2-4-8-18(14)24-22/h1-8,23-24H,9-12H2,(H,25,26)(H,27,28)	WKVZBEWEEYDDMO-UHFFFAOYSA-N	3979	2,2 -Dithiobis(1H-indole-3-propanoic acid)::3-(2-{[3-(2-carboxyethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanoic acid::CHEMBL79704::dithiobis(1H-indole-3-alkanoic acid) deriv. 27	Epidermal growth factor receptor	Homo sapiens		 4200							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3979	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3979&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328558	8033676		CHEMBL79704			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5915	Cn1c(SSc2c(CCC(O)=O)c3ccccc3n2C)c(CCC(O)=O)c2ccccc12	InChI=1S/C24H24N2O4S2/c1-25-19-9-5-3-7-15(19)17(11-13-21(27)28)23(25)31-32-24-18(12-14-22(29)30)16-8-4-6-10-20(16)26(24)2/h3-10H,11-14H2,1-2H3,(H,27,28)(H,29,30)	YEQMSCNOXHUWHS-UHFFFAOYSA-N	3980	3-(2-{[3-(2-carboxyethyl)-1-methyl-1H-indol-2-yl]disulfanyl}-1-methyl-1H-indol-3-yl)propanoic acid::2,2 -Dithiobis(1-methyl-1H-indole-3-propanoic acid)::dithiobis(1H-indole-3-alkanoic acid) deriv. 28	Epidermal growth factor receptor	Homo sapiens		 3100							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3980	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3980&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328559	8033677					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5916	COC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)OC)[nH]c2ccccc12	InChI=1S/C24H24N2O4S2/c1-29-21(27)13-11-17-15-7-3-5-9-19(15)25-23(17)31-32-24-18(12-14-22(28)30-2)16-8-4-6-10-20(16)26-24/h3-10,25-26H,11-14H2,1-2H3	ZMWAFESFFVDUCV-UHFFFAOYSA-N	3981	1 H-indole-3-alkanamide deriv. 7::methyl 3-(2-{[3-(3-methoxy-3-oxopropyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanoate::Dimethyl 2,2 -Dithiobis(1H-indole-3-propanoate)::dithiobis(1H-indole-3-alkanoic acid) deriv. 29	Epidermal growth factor receptor	Homo sapiens		 21000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3981	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3981&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328560	8033678					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5917	COC(=O)CCc1c(SSc2c(CCC(=O)OC)c3ccccc3n2C)n(C)c2ccccc12	InChI=1S/C26H28N2O4S2/c1-27-21-11-7-5-9-17(21)19(13-15-23(29)31-3)25(27)33-34-26-20(14-16-24(30)32-4)18-10-6-8-12-22(18)28(26)2/h5-12H,13-16H2,1-4H3	DINHMKFQZIUDRX-UHFFFAOYSA-N	3982	Dimethyl 2,2 -dithiobis(1-methyl-1H-indole-3-propanoate)::methyl 3-(2-{[3-(3-methoxy-3-oxopropyl)-1-methyl-1H-indol-2-yl]disulfanyl}-1-methyl-1H-indol-3-yl)propanoate::CHEMBL314029::dithiobis(1H-indole-3-alkanoic acid) deriv. 30	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3982	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3982&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328561	8033679		CHEMBL314029			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5918	Cc1ccc2[nH]c(SSc3[nH]c4ccc(C)cc4c3CCC(O)=O)c(CCC(O)=O)c2c1	InChI=1S/C24H24N2O4S2/c1-13-3-7-19-17(11-13)15(5-9-21(27)28)23(25-19)31-32-24-16(6-10-22(29)30)18-12-14(2)4-8-20(18)26-24/h3-4,7-8,11-12,25-26H,5-6,9-10H2,1-2H3,(H,27,28)(H,29,30)	LOGBNOOWFMSMKQ-UHFFFAOYSA-N	3983	3-(2-{[3-(2-carboxyethyl)-5-methyl-1H-indol-2-yl]disulfanyl}-5-methyl-1H-indol-3-yl)propanoic acid::2,2 -Dithiobis(5-methyl-1H-indole-3-propanoic acid)::dithiobis(1H-indole-3-alkanoic acid) deriv. 31	Epidermal growth factor receptor	Homo sapiens		 8400							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3983	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3983&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328562	8033680					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5919	Cc1ccc2c(CCC(O)=O)c(SSc3[nH]c4cc(C)ccc4c3CCC(O)=O)[nH]c2c1	InChI=1S/C24H24N2O4S2/c1-13-3-5-15-17(7-9-21(27)28)23(25-19(15)11-13)31-32-24-18(8-10-22(29)30)16-6-4-14(2)12-20(16)26-24/h3-6,11-12,25-26H,7-10H2,1-2H3,(H,27,28)(H,29,30)	FBTLWPVPMRFARV-UHFFFAOYSA-N	3984	2,2 -Dithiobis(6-methyl-1H-indole-3-propanoic acid)::3-(2-{[3-(2-carboxyethyl)-6-methyl-1H-indol-2-yl]disulfanyl}-6-methyl-1H-indol-3-yl)propanoic acid::dithiobis(1H-indole-3-alkanoic acid) deriv. 32	Epidermal growth factor receptor	Homo sapiens		 2900							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3984	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3984&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328563	8033681					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5920	Cc1cccc2c(CCC(O)=O)c(SSc3[nH]c4c(C)cccc4c3CCC(O)=O)[nH]c12	InChI=1S/C24H24N2O4S2/c1-13-5-3-7-15-17(9-11-19(27)28)23(25-21(13)15)31-32-24-18(10-12-20(29)30)16-8-4-6-14(2)22(16)26-24/h3-8,25-26H,9-12H2,1-2H3,(H,27,28)(H,29,30)	VSGQCGRYAAEEEL-UHFFFAOYSA-N	3985	3-(2-{[3-(2-carboxyethyl)-7-methyl-1H-indol-2-yl]disulfanyl}-7-methyl-1H-indol-3-yl)propanoic acid::2,2 -Dithiobis(7-methyl-1H-indole-3-propanoic acid)::dithiobis(1H-indole-3-alkanoic acid) deriv. 33	Epidermal growth factor receptor	Homo sapiens		 1500							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3985&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328564	8033682					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5921	OC(=O)CCCc1c(SSc2[nH]c3ccccc3c2CCCC(O)=O)[nH]c2ccccc12	InChI=1S/C24H24N2O4S2/c27-21(28)13-5-9-17-15-7-1-3-11-19(15)25-23(17)31-32-24-18(10-6-14-22(29)30)16-8-2-4-12-20(16)26-24/h1-4,7-8,11-12,25-26H,5-6,9-10,13-14H2,(H,27,28)(H,29,30)	NDFJNVBQNXXJTB-UHFFFAOYSA-N	3986	2,2 -Dithiobis(1H-indole-3-butanoic acid)::4-(2-{[3-(3-carboxypropyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)butanoic acid::dithiobis(1H-indole-3-alkanoic acid) deriv. 34	Epidermal growth factor receptor	Homo sapiens		 18000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3986	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3986&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328565	8033683					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5922	Cn1c(SSc2c(CCCC(O)=O)c3ccccc3n2C)c(CCCC(O)=O)c2ccccc12	InChI=1S/C26H28N2O4S2/c1-27-21-13-5-3-9-17(21)19(11-7-15-23(29)30)25(27)33-34-26-20(12-8-16-24(31)32)18-10-4-6-14-22(18)28(26)2/h3-6,9-10,13-14H,7-8,11-12,15-16H2,1-2H3,(H,29,30)(H,31,32)	ODNORDFRKWRXFV-UHFFFAOYSA-N	3987	2,2 -Dithiobis(1-methyl-1H-indole-3-butanoic acid)::4-(2-{[3-(3-carboxypropyl)-1-methyl-1H-indol-2-yl]disulfanyl}-1-methyl-1H-indol-3-yl)butanoic acid::dithiobis(1H-indole-3-alkanoic acid) deriv. 35	Epidermal growth factor receptor	Homo sapiens		 8300							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3987&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328566	8033684					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5923	COC(=O)CCCc1c(SSc2[nH]c3ccccc3c2CCCC(=O)OC)[nH]c2ccccc12	InChI=1S/C26H28N2O4S2/c1-31-23(29)15-7-11-19-17-9-3-5-13-21(17)27-25(19)33-34-26-20(12-8-16-24(30)32-2)18-10-4-6-14-22(18)28-26/h3-6,9-10,13-14,27-28H,7-8,11-12,15-16H2,1-2H3	LTADMBRWQKYQNQ-UHFFFAOYSA-N	3988	methyl 4-(2-{[3-(4-methoxy-4-oxobutyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)butanoate::Dimethyl 2,2 -Dithiobis(1H-indole-3-butanoate)::dithiobis(1H-indole-3-alkanoic acid) deriv. 36	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3988	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3988&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328567	8033685					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5924	COC(=O)CCCc1c(SSc2c(CCCC(=O)OC)c3ccccc3n2C)n(C)c2ccccc12	InChI=1S/C28H32N2O4S2/c1-29-23-15-7-5-11-19(23)21(13-9-17-25(31)33-3)27(29)35-36-28-22(14-10-18-26(32)34-4)20-12-6-8-16-24(20)30(28)2/h5-8,11-12,15-16H,9-10,13-14,17-18H2,1-4H3	IOJZVEHURUQVIF-UHFFFAOYSA-N	3989	Dimethyl 2,2 -Dithiobis(1-methyl-1H-indole-3-butanoate)::methyl 4-(2-{[3-(4-methoxy-4-oxobutyl)-1-methyl-1H-indol-2-yl]disulfanyl}-1-methyl-1H-indol-3-yl)butanoate::dithiobis(1H-indole-3-alkanoic acid) deriv. 37	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00069a003	10.7270/Q2RJ4GNS	8355247	aid1795584		Thompson, AM; Rewcastle, GW; Tercel, M; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	8/20/1993	4/21/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3989&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328568	8033686					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5925	O=C(Cc1c(SSc2[nH]c3ccccc3c2CC(=O)NCc2ccccc2)[nH]c2ccccc12)NCc1ccccc1	InChI=1S/C34H30N4O2S2/c39-31(35-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)37-33(27)41-42-34-28(26-16-8-10-18-30(26)38-34)20-32(40)36-22-24-13-5-2-6-14-24/h1-18,37-38H,19-22H2,(H,35,39)(H,36,40)	ATSKCEZXZQLMAV-UHFFFAOYSA-N	3990	N-benzyl-2-[2-({3-[(benzylcarbamoyl)methyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]acetamide::1 H-indole-3-alkanamide deriv. 10a	Epidermal growth factor receptor	Homo sapiens		 38000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3990	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3990&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328569	8033687					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5926	N#CCc1c(SSc2[nH]c3ccccc3c2CC#N)[nH]c2ccccc12	InChI=1S/C20H14N4S2/c21-11-9-15-13-5-1-3-7-17(13)23-19(15)25-26-20-16(10-12-22)14-6-2-4-8-18(14)24-20/h1-8,23-24H,9-10H2	WRQVNXDOWPRYHH-UHFFFAOYSA-N	3991	2-(2-{[3-(cyanomethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)acetonitrile::1 H-indole-3-alkanamide deriv. 10b	Epidermal growth factor receptor	Homo sapiens		 32000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3991&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328570	8033688					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5927	OC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(O)=O)[nH]c2ccccc12	InChI=1S/C22H20N2O4S2/c25-19(26)11-9-15-13-5-1-3-7-17(13)23-21(15)29-30-22-16(10-12-20(27)28)14-6-2-4-8-18(14)24-22/h1-8,23-24H,9-12H2,(H,25,26)(H,27,28)	WKVZBEWEEYDDMO-UHFFFAOYSA-N	3979	2,2 -Dithiobis(1H-indole-3-propanoic acid)::3-(2-{[3-(2-carboxyethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanoic acid::CHEMBL79704::dithiobis(1H-indole-3-alkanoic acid) deriv. 27	Epidermal growth factor receptor	Homo sapiens		 4800					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3979	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3979&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328558	8033676		CHEMBL79704			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5928	COC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)OC)[nH]c2ccccc12	InChI=1S/C24H24N2O4S2/c1-29-21(27)13-11-17-15-7-3-5-9-19(15)25-23(17)31-32-24-18(12-14-22(28)30-2)16-8-4-6-10-20(16)26-24/h3-10,25-26H,11-14H2,1-2H3	ZMWAFESFFVDUCV-UHFFFAOYSA-N	3981	1 H-indole-3-alkanamide deriv. 7::methyl 3-(2-{[3-(3-methoxy-3-oxopropyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanoate::Dimethyl 2,2 -Dithiobis(1H-indole-3-propanoate)::dithiobis(1H-indole-3-alkanoic acid) deriv. 29	Epidermal growth factor receptor	Homo sapiens		 21000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3981	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3981&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328560	8033678					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5929	N#CCCc1c(SSc2[nH]c3ccccc3c2CCC#N)[nH]c2ccccc12	InChI=1S/C22H18N4S2/c23-13-5-9-17-15-7-1-3-11-19(15)25-21(17)27-28-22-18(10-6-14-24)16-8-2-4-12-20(16)26-22/h1-4,7-8,11-12,25-26H,5-6,9-10H2	BWFSEWLGHWAHGL-UHFFFAOYSA-N	3994	3-(2-{[3-(2-cyanoethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanenitrile::1 H-indole-3-alkanamide deriv. 10c	Epidermal growth factor receptor	Homo sapiens		 47000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3994&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328571	8033689					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5930	[O-][N+](=O)CCc1c(SSc2[nH]c3ccccc3c2CC[N+]([O-])=O)[nH]c2ccccc12	InChI=1S/C20H18N4O4S2/c25-23(26)11-9-15-13-5-1-3-7-17(13)21-19(15)29-30-20-16(10-12-24(27)28)14-6-2-4-8-18(14)22-20/h1-8,21-22H,9-12H2	WFFWDHORGIOMIR-UHFFFAOYSA-N	3995	3-(2-nitroethyl)-2-{[3-(2-nitroethyl)-1H-indol-2-yl]disulfanyl}-1H-indole::1 H-indole-3-alkanamide deriv. 10d	Epidermal growth factor receptor	Homo sapiens		 89000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3995	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3995&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328572	8033690					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5931	NC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(N)=O)[nH]c2ccccc12	InChI=1S/C22H22N4O2S2/c23-19(27)11-9-15-13-5-1-3-7-17(13)25-21(15)29-30-22-16(10-12-20(24)28)14-6-2-4-8-18(14)26-22/h1-8,25-26H,9-12H2,(H2,23,27)(H2,24,28)	HMHMZJJRNBZGQN-UHFFFAOYSA-N	3996	2,2 -Dithiobis(1H-indole-3-propanamide)::3-(2-{[3-(2-carbamoylethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanamide::1 H-indole-3-alkanamide deriv. 10e	Epidermal growth factor receptor	Homo sapiens		 16000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3996	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3996&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328573	8033691					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5932	CNC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NC)[nH]c2ccccc12	InChI=1S/C24H26N4O2S2/c1-25-21(29)13-11-17-15-7-3-5-9-19(15)27-23(17)31-32-24-18(12-14-22(30)26-2)16-8-4-6-10-20(16)28-24/h3-10,27-28H,11-14H2,1-2H3,(H,25,29)(H,26,30)	YZHVMIJXSAQUTB-UHFFFAOYSA-N	3997	N-methyl-3-[2-({3-[2-(methylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]propanamide::1 H-indole-3-alkanamide deriv. 10f	Epidermal growth factor receptor	Homo sapiens		 9400					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3997&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328574	8033692					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5933	CONC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NOC)[nH]c2ccccc12	InChI=1S/C24H26N4O4S2/c1-31-27-21(29)13-11-17-15-7-3-5-9-19(15)25-23(17)33-34-24-18(12-14-22(30)28-32-2)16-8-4-6-10-20(16)26-24/h3-10,25-26H,11-14H2,1-2H3,(H,27,29)(H,28,30)	BYVXOMRKIJSLRU-UHFFFAOYSA-N	3998	N-methoxy-3-[2-({3-[2-(methoxycarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]propanamide::1 H-indole-3-alkanamide deriv. 10g	Epidermal growth factor receptor	Homo sapiens		 68000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3998	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3998&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328575	8033693					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5934	CN(C)C(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)N(C)C)[nH]c2ccccc12	InChI=1S/C26H30N4O2S2/c1-29(2)23(31)15-13-19-17-9-5-7-11-21(17)27-25(19)33-34-26-20(14-16-24(32)30(3)4)18-10-6-8-12-22(18)28-26/h5-12,27-28H,13-16H2,1-4H3	CFTJYIOLGANXGV-UHFFFAOYSA-N	3999	3-[2-({3-[2-(dimethylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]-N,N-dimethylpropanamide::1 H-indole-3-alkanamide deriv. 10h	Epidermal growth factor receptor	Homo sapiens		 12000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3999&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328576	8033694					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5935	O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)Nc2ccccc2)[nH]c2ccccc12)Nc1ccccc1	InChI=1S/C34H30N4O2S2/c39-31(35-23-11-3-1-4-12-23)21-19-27-25-15-7-9-17-29(25)37-33(27)41-42-34-28(26-16-8-10-18-30(26)38-34)20-22-32(40)36-24-13-5-2-6-14-24/h1-18,37-38H,19-22H2,(H,35,39)(H,36,40)	MGXQRBDSSCCBIV-UHFFFAOYSA-N	4000	N-phenyl-3-[2-({3-[2-(phenylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]propanamide::2,2-Dithiobis(N-phenyl-1H-indole-3-propanamide)::1 H-indole-3-alkanamide deriv. 10i	Epidermal growth factor receptor	Homo sapiens		 25000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4000	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4000&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328577	8033695					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5936	O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NCc2ccccc2)[nH]c2ccccc12)NCc1ccccc1	InChI=1S/C36H34N4O2S2/c41-33(37-23-25-11-3-1-4-12-25)21-19-29-27-15-7-9-17-31(27)39-35(29)43-44-36-30(28-16-8-10-18-32(28)40-36)20-22-34(42)38-24-26-13-5-2-6-14-26/h1-18,39-40H,19-24H2,(H,37,41)(H,38,42)	JIEAIEPFEUNUQF-UHFFFAOYSA-N	4001	N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]propanamide::1 H-indole-3-alkanamide deriv. 10j	Epidermal growth factor receptor	Homo sapiens		 850					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4001&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328578	8033696					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5937	COC(=O)c1ccc(CNC(=O)CCc2c(SSc3[nH]c4ccccc4c3CCC(=O)NCc3ccc(cc3)C(=O)OC)[nH]c3ccccc23)cc1	InChI=1S/C40H38N4O6S2/c1-49-39(47)27-15-11-25(12-16-27)23-41-35(45)21-19-31-29-7-3-5-9-33(29)43-37(31)51-52-38-32(30-8-4-6-10-34(30)44-38)20-22-36(46)42-24-26-13-17-28(18-14-26)40(48)50-2/h3-18,43-44H,19-24H2,1-2H3,(H,41,45)(H,42,46)	SEFPCKRFUORUQG-UHFFFAOYSA-N	4002	methyl 4-({3-[2-({3-[2-({[4-(methoxycarbonyl)phenyl]methyl}carbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]propanamido}methyl)benzoate::2,2 -dithiobis[N-[[4-(methoxycarbonyl)phenyl]methyl]-1H-indole-3-propanamide]::1 H-indole-3-alkanamide deriv. 10k	Epidermal growth factor receptor	Homo sapiens		 44000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4002&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328579	8033697					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5938	OC(=O)c1ccc(CNC(=O)CCc2c(SSc3[nH]c4ccccc4c3CCC(=O)NCc3ccc(cc3)C(O)=O)[nH]c3ccccc23)cc1	InChI=1S/C38H34N4O6S2/c43-33(39-21-23-9-13-25(14-10-23)37(45)46)19-17-29-27-5-1-3-7-31(27)41-35(29)49-50-36-30(28-6-2-4-8-32(28)42-36)18-20-34(44)40-22-24-11-15-26(16-12-24)38(47)48/h1-16,41-42H,17-22H2,(H,39,43)(H,40,44)(H,45,46)(H,47,48)	WFDPOLGETIKDCU-UHFFFAOYSA-N	4003	2,2 -Dithiobis[N-[(4-carboxypheny1)methyl]-1H-indole-3-propanamide]::4-{[3-(2-{[3-(2-{[(4-carboxyphenyl)methyl]carbamoyl}ethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanamido]methyl}benzoic acid::1 H-indole-3-alkanamide deriv. 10l	Epidermal growth factor receptor	Homo sapiens		 7400					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4003&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328580	8033698					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5939	COC(=O)c1ccc(CNC(=O)CCc2c(SSc3[nH]c4ccccc4c3CCC(=O)NCc3ccc(C(=O)OC)c(O)c3)[nH]c3ccccc23)cc1O	InChI=1S/C40H38N4O8S2/c1-51-39(49)29-13-11-23(19-33(29)45)21-41-35(47)17-15-27-25-7-3-5-9-31(25)43-37(27)53-54-38-28(26-8-4-6-10-32(26)44-38)16-18-36(48)42-22-24-12-14-30(34(46)20-24)40(50)52-2/h3-14,19-20,43-46H,15-18,21-22H2,1-2H3,(H,41,47)(H,42,48)	WNVTVRRFAUAZBO-UHFFFAOYSA-N	4004	2,2 -Dithiobis[N-[[3-hydroxy-4-(methoxycarbonyl)phenyl]methyl]-1H-indole-3-propanamide]::1 H-indole-3-alkanamide deriv. 10m	Epidermal growth factor receptor	Homo sapiens		 100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4004&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328581	8033699					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5940	OC(=O)c1ccc(CNC(=O)CCc2c(SSc3[nH]c4ccccc4c3CCC(=O)NCc3ccc(C(O)=O)c(O)c3)[nH]c3ccccc23)cc1O	InChI=1S/C38H34N4O8S2/c43-31-17-21(9-11-27(31)37(47)48)19-39-33(45)15-13-25-23-5-1-3-7-29(23)41-35(25)51-52-36-26(24-6-2-4-8-30(24)42-36)14-16-34(46)40-20-22-10-12-28(38(49)50)32(44)18-22/h1-12,17-18,41-44H,13-16,19-20H2,(H,39,45)(H,40,46)(H,47,48)(H,49,50)	KUKWJPKUERJESV-UHFFFAOYSA-N	4005	2,2 -Dithiobis[N-[(4-carboxy-3-hydroxyphenyl)methyl]-1H-indole-3-propanamide]::4-{[3-(2-{[3-(2-{[(4-carboxy-3-hydroxyphenyl)methyl]carbamoyl}ethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanamido]methyl}-2-hydroxybenzoic acid::1 H-indole-3-alkanamide deriv. 10n	Epidermal growth factor receptor	Homo sapiens		 8500					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4005	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4005&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328582	8033700					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5941	O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NCCc2ccccc2)[nH]c2ccccc12)NCCc1ccccc1	InChI=1S/C38H38N4O2S2/c43-35(39-25-23-27-11-3-1-4-12-27)21-19-31-29-15-7-9-17-33(29)41-37(31)45-46-38-32(30-16-8-10-18-34(30)42-38)20-22-36(44)40-26-24-28-13-5-2-6-14-28/h1-18,41-42H,19-26H2,(H,39,43)(H,40,44)	MPGQFAMKTLPOPX-UHFFFAOYSA-N	4006	N-(2-phenylethyl)-3-{2-[(3-{2-[(2-phenylethyl)carbamoyl]ethyl}-1H-indol-2-yl)disulfanyl]-1H-indol-3-yl}propanamide::1 H-indole-3-alkanamide deriv. 10o	Epidermal growth factor receptor	Homo sapiens		 24000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4006&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328583	8033701					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5942	CC(=O)NC(Cc1c(SSc2[nH]c3ccccc3c2CC(NC(C)=O)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1	InChI=1S/C40H40N6O4S2/c1-25(47)43-35(37(49)41-23-27-13-5-3-6-14-27)21-31-29-17-9-11-19-33(29)45-39(31)51-52-40-32(30-18-10-12-20-34(30)46-40)22-36(44-26(2)48)38(50)42-24-28-15-7-4-8-16-28/h3-20,35-36,45-46H,21-24H2,1-2H3,(H,41,49)(H,42,50)(H,43,47)(H,44,48)	MTTNYIXYAZMASA-UHFFFAOYSA-N	4007	N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)-2-acetamidoethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]-2-acetamidopropanamide::2,2 -Dithiobis[alpha-(acety1amino)-N-(phenylmethyl)-1H-indole-3-propanamide]: Isolation of Diastereoisomer Pairs::1 H-indole-3-alkanamide deriv. 10p	Epidermal growth factor receptor	Homo sapiens		 51000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4007&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328584	8033702					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5943	FC(F)(F)C(=O)NC(Cc1c(SSc2[nH]c3ccccc3c2CC(NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1	InChI=1S/C40H34F6N6O4S2/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-58-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)	HPPRVVIEPVVPDV-UHFFFAOYSA-N	4008	N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)-2-(2,2,2-trifluoroacetamido)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]-2-(2,2,2-trifluoroacetamido)propanamide::2,2-Dithiobis[N-benzyl-N-(trifluoroacetyl)tryptophanamide]::1 H-indole-3-alkanamide deriv. 10q	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4008&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328585	8033703					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5944	NC(Cc1c(SSc2[nH]c3ccccc3c2CC(N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1	InChI=1S/C36H36N6O2S2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)	MCNYLFAPBYIPPD-UHFFFAOYSA-N	3351	CHEMBL336174::2-amino-3-[2-({3-[2-amino-2-(benzylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]-N-benzylpropanamide::dithiobis(1H-indoles) deriv. 4	Epidermal growth factor receptor	Homo sapiens		 7600					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3351	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3351&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328097	8033093		CHEMBL336174			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5945	CC(=O)OC(Cc1c(SSc2[nH]c3ccccc3c2CC(OC(C)=O)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1	InChI=1S/C40H38N4O6S2/c1-25(45)49-35(37(47)41-23-27-13-5-3-6-14-27)21-31-29-17-9-11-19-33(29)43-39(31)51-52-40-32(30-18-10-12-20-34(30)44-40)22-36(50-26(2)46)38(48)42-24-28-15-7-4-8-16-28/h3-20,35-36,43-44H,21-24H2,1-2H3,(H,41,47)(H,42,48)	ULJVYCBHZIELSM-UHFFFAOYSA-N	4010	1-(benzylcarbamoyl)-2-[2-({3-[2-(benzylcarbamoyl)-2-(acetyloxy)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]ethyl acetate::1 H-indole-3-alkanamide deriv. 10s	Epidermal growth factor receptor	Homo sapiens		 28000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4010&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328586	8033704					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5946	OC(Cc1c(SSc2[nH]c3ccccc3c2CC(O)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1	InChI=1S/C36H34N4O4S2/c41-31(33(43)37-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)39-35(27)45-46-36-28(26-16-8-10-18-30(26)40-36)20-32(42)34(44)38-22-24-13-5-2-6-14-24/h1-18,31-32,39-42H,19-22H2,(H,37,43)(H,38,44)	ZZEJZBLCZXHUBG-UHFFFAOYSA-N	4011	N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)-2-hydroxyethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]-2-hydroxypropanamide::2,2 -Dithiobis[alpha-hydroxy-N-(phenylmethyl)-1H-indole-3-propanamide]::1 H-indole-3-alkanamide deriv. 10t	Epidermal growth factor receptor	Homo sapiens		 14000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4011&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328587	8033705					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5947	O=C(CCCc1c(SSc2[nH]c3ccccc3c2CCCC(=O)NCc2ccccc2)[nH]c2ccccc12)NCc1ccccc1	InChI=1S/C38H38N4O2S2/c43-35(39-25-27-13-3-1-4-14-27)23-11-19-31-29-17-7-9-21-33(29)41-37(31)45-46-38-32(30-18-8-10-22-34(30)42-38)20-12-24-36(44)40-26-28-15-5-2-6-16-28/h1-10,13-18,21-22,41-42H,11-12,19-20,23-26H2,(H,39,43)(H,40,44)	OHULBTKPWJQBHV-UHFFFAOYSA-N	4012	N-benzyl-4-[2-({3-[3-(benzylcarbamoyl)propyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]butanamide::1 H-indole-3-alkanamide deriv. 10u	Epidermal growth factor receptor	Homo sapiens		 100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4012&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328588	8033706					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5948	O=C(CC1C(=S)Nc2ccccc12)NCc1ccccc1	InChI=1S/C17H16N2OS/c20-16(18-11-12-6-2-1-3-7-12)10-14-13-8-4-5-9-15(13)19-17(14)21/h1-9,14H,10-11H2,(H,18,20)(H,19,21)	AZIKYQWSIXOHGI-UHFFFAOYSA-N	4013	N-benzyl-2-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)acetamide::1 H-indole-3-alkanamide deriv. 11a	Epidermal growth factor receptor	Homo sapiens		 100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4013&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328589	8033707							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5949	NC(=O)CCC1C(=S)Nc2ccccc12	InChI=1S/C11H12N2OS/c12-10(14)6-5-8-7-3-1-2-4-9(7)13-11(8)15/h1-4,8H,5-6H2,(H2,12,14)(H,13,15)	HNVREGXKMXLVDH-UHFFFAOYSA-N	4014	2,3-Dihydro-2-thioxo-1H-indole-3-propanamide::3-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)propanamide::1 H-indole-3-alkanamide deriv. 11e	Epidermal growth factor receptor	Homo sapiens		 22000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4014&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328590	8033708							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5950	O=C(CCC1C(=S)Nc2ccccc12)NCc1ccccc1	InChI=1S/C18H18N2OS/c21-17(19-12-13-6-2-1-3-7-13)11-10-15-14-8-4-5-9-16(14)20-18(15)22/h1-9,15H,10-12H2,(H,19,21)(H,20,22)	FRECTLXXXNGYET-UHFFFAOYSA-N	4015	N-benzyl-3-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)propanamide::1 H-indole-3-alkanamide deriv. 11j	Epidermal growth factor receptor	Homo sapiens		 100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00031a009	10.7270/Q2MS3QZH	7510340	aid1795588		Thompson, AM; Fry, DW; Kraker, AJ; Denny, WA	3/4/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4015&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328591	8033709							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5972	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3ccccc3n2C)c(C(=O)Nc2ccccc2)c2ccccc12	InChI=1S/C32H26N4O2S2/c1-35-25-19-11-9-17-23(25)27(29(37)33-21-13-5-3-6-14-21)31(35)39-40-32-28(24-18-10-12-20-26(24)36(32)2)30(38)34-22-15-7-4-8-16-22/h3-20H,1-2H3,(H,33,37)(H,34,38)	PRTBWEHHMHBKER-UHFFFAOYSA-N	4016	1-methyl-2-{[1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-N-phenyl-1H-indole-3-carboxamide::CHEMBL304414::2,2 -Dithiobis( 1-methyl-N-phenyl- 1H-indole-3-carboxamide)::dithiobis(1H-indole-3-carboxamide) deriv. 10a	Epidermal growth factor receptor	Homo sapiens		 10000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4016&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328592	8033710		CHEMBL304414			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5973	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3c(Cl)cccc3n2C)c(C(=O)Nc2ccccc2)c2c(Cl)cccc12	InChI=1S/C32H24Cl2N4O2S2/c1-37-23-17-9-15-21(33)25(23)27(29(39)35-19-11-5-3-6-12-19)31(37)41-42-32-28(30(40)36-20-13-7-4-8-14-20)26-22(34)16-10-18-24(26)38(32)2/h3-18H,1-2H3,(H,35,39)(H,36,40)	BLTLMFALRUNXKG-UHFFFAOYSA-N	4017	4-chloro-2-{[4-chloro-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10b	Epidermal growth factor receptor	Homo sapiens		 100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4017&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328593	8033711					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5974	Cc1cccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4c(C)cccc4n3C)c(C(=O)Nc3ccccc3)c12	InChI=1S/C34H30N4O2S2/c1-21-13-11-19-25-27(21)29(31(39)35-23-15-7-5-8-16-23)33(37(25)3)41-42-34-30(32(40)36-24-17-9-6-10-18-24)28-22(2)14-12-20-26(28)38(34)4/h5-20H,1-4H3,(H,35,39)(H,36,40)	LDDNNZKKMXSXPS-UHFFFAOYSA-N	4018	2-{[1,4-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1,4-dimethyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10c	Epidermal growth factor receptor	Homo sapiens		>100000  					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4018	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4018&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328594	8033712					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5975	COc1cccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4c(OC)cccc4n3C)c(C(=O)Nc3ccccc3)c12	InChI=1S/C34H30N4O4S2/c1-37-23-17-11-19-25(41-3)27(23)29(31(39)35-21-13-7-5-8-14-21)33(37)43-44-34-30(32(40)36-22-15-9-6-10-16-22)28-24(38(34)2)18-12-20-26(28)42-4/h5-20H,1-4H3,(H,35,39)(H,36,40)	MCAHNIWHTWDORH-UHFFFAOYSA-N	4019	4-methoxy-2-{[4-methoxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10d	Epidermal growth factor receptor	Homo sapiens		>100000  					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4019&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328595	8033713					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5976	CC(=O)Oc1cccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4c(OC(C)=O)cccc4n3C)c(C(=O)Nc3ccccc3)c12	InChI=1S/C36H30N4O6S2/c1-21(41)45-27-19-11-17-25-29(27)31(33(43)37-23-13-7-5-8-14-23)35(39(25)3)47-48-36-32(34(44)38-24-15-9-6-10-16-24)30-26(40(36)4)18-12-20-28(30)46-22(2)42/h5-20H,1-4H3,(H,37,43)(H,38,44)	AURYYBJWNGTKQC-UHFFFAOYSA-N	4020	2-{[4-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-3-(phenylcarbamoyl)-1H-indol-4-yl acetate::dithiobis(1H-indole-3-carboxamide) deriv. 10e	Epidermal growth factor receptor	Homo sapiens		 20000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4020	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4020&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328596	8033714					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5977	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(F)ccc3n2C)c(C(=O)Nc2ccccc2)c2cc(F)ccc12	InChI=1S/C32H24F2N4O2S2/c1-37-25-15-13-19(33)17-23(25)27(29(39)35-21-9-5-3-6-10-21)31(37)41-42-32-28(30(40)36-22-11-7-4-8-12-22)24-18-20(34)14-16-26(24)38(32)2/h3-18H,1-2H3,(H,35,39)(H,36,40)	YPMYGRXQSAAYHQ-UHFFFAOYSA-N	4021	5-fluoro-2-{[5-fluoro-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10f	Epidermal growth factor receptor	Homo sapiens		>100000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4021&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328597	8033715					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5978	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(Cl)ccc3n2C)c(C(=O)Nc2ccccc2)c2cc(Cl)ccc12	InChI=1S/C32H24Cl2N4O2S2/c1-37-25-15-13-19(33)17-23(25)27(29(39)35-21-9-5-3-6-10-21)31(37)41-42-32-28(30(40)36-22-11-7-4-8-12-22)24-18-20(34)14-16-26(24)38(32)2/h3-18H,1-2H3,(H,35,39)(H,36,40)	QQYQXWACNBHSDE-UHFFFAOYSA-N	4022	5-chloro-2-{[5-chloro-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::CHEMBL293889::dithiobis(1H-indole-3-carboxamide) deriv. 10g	Epidermal growth factor receptor	Homo sapiens		 4300					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4022&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328598	8033716		CHEMBL293889			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5979	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(Br)ccc3n2C)c(C(=O)Nc2ccccc2)c2cc(Br)ccc12	InChI=1S/C32H24Br2N4O2S2/c1-37-25-15-13-19(33)17-23(25)27(29(39)35-21-9-5-3-6-10-21)31(37)41-42-32-28(30(40)36-22-11-7-4-8-12-22)24-18-20(34)14-16-26(24)38(32)2/h3-18H,1-2H3,(H,35,39)(H,36,40)	GCAJVGAKBPOEBH-UHFFFAOYSA-N	4023	5-bromo-2-{[5-bromo-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10h	Epidermal growth factor receptor	Homo sapiens		 11400					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4023&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328599	8033717					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5980	Cc1ccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4cc(C)ccc4n3C)c(C(=O)Nc3ccccc3)c2c1	InChI=1S/C34H30N4O2S2/c1-21-15-17-27-25(19-21)29(31(39)35-23-11-7-5-8-12-23)33(37(27)3)41-42-34-30(32(40)36-24-13-9-6-10-14-24)26-20-22(2)16-18-28(26)38(34)4/h5-20H,1-4H3,(H,35,39)(H,36,40)	TUPADNGSOVYYFT-UHFFFAOYSA-N	4024	2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1,5-dimethyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10i	Epidermal growth factor receptor	Homo sapiens		>100000  					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4024&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328600	8033718					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5981	COc1ccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4cc(OC)ccc4n3C)c(C(=O)Nc3ccccc3)c2c1	InChI=1S/C34H30N4O4S2/c1-37-27-17-15-23(41-3)19-25(27)29(31(39)35-21-11-7-5-8-12-21)33(37)43-44-34-30(32(40)36-22-13-9-6-10-14-22)26-20-24(42-4)16-18-28(26)38(34)2/h5-20H,1-4H3,(H,35,39)(H,36,40)	ACEXKVMSZJJLTI-UHFFFAOYSA-N	4025	5-methoxy-2-{[5-methoxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10j	Epidermal growth factor receptor	Homo sapiens		>100000  					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4025&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328601	8033719					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5982	CC(=O)Oc1ccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4cc(OC(C)=O)ccc4n3C)c(C(=O)Nc3ccccc3)c2c1	InChI=1S/C36H30N4O6S2/c1-21(41)45-25-15-17-29-27(19-25)31(33(43)37-23-11-7-5-8-12-23)35(39(29)3)47-48-36-32(34(44)38-24-13-9-6-10-14-24)28-20-26(46-22(2)42)16-18-30(28)40(36)4/h5-20H,1-4H3,(H,37,43)(H,38,44)	DQTFQGFYHRMPLB-UHFFFAOYSA-N	4026	2-{[5-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-3-(phenylcarbamoyl)-1H-indol-5-yl acetate::dithiobis(1H-indole-3-carboxamide) deriv. 10k	Epidermal growth factor receptor	Homo sapiens		 5300					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4026	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4026&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328602	8033720					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5994	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(O)ccc3n2C)c(C(=O)Nc2ccccc2)c2cc(O)ccc12	InChI=1S/C32H26N4O4S2/c1-35-25-15-13-21(37)17-23(25)27(29(39)33-19-9-5-3-6-10-19)31(35)41-42-32-28(30(40)34-20-11-7-4-8-12-20)24-18-22(38)14-16-26(24)36(32)2/h3-18,37-38H,1-2H3,(H,33,39)(H,34,40)	IWMOCSLVFAOWEJ-UHFFFAOYSA-N	4027	5-hydroxy-2-{[5-hydroxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::2,2 -Dithiobis( 5-hydroxy- 1-methyl-N-phenylindole-3-carboxamide)::dithiobis(1H-indole-3-carboxamide) deriv. 10l	Epidermal growth factor receptor	Homo sapiens		 40500							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4027&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328603	8033721					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5995	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(ccc3n2C)C(F)(F)F)c(C(=O)Nc2ccccc2)c2cc(ccc12)C(F)(F)F	InChI=1S/C34H24F6N4O2S2/c1-43-25-15-13-19(33(35,36)37)17-23(25)27(29(45)41-21-9-5-3-6-10-21)31(43)47-48-32-28(30(46)42-22-11-7-4-8-12-22)24-18-20(34(38,39)40)14-16-26(24)44(32)2/h3-18H,1-2H3,(H,41,45)(H,42,46)	HSEZITPLLAUQOF-UHFFFAOYSA-N	4028	1-methyl-2-{[1-methyl-3-(phenylcarbamoyl)-5-(trifluoromethyl)-1H-indol-2-yl]disulfanyl}-N-phenyl-5-(trifluoromethyl)-1H-indole-3-carboxamide::CHEMBL61278::dithiobis(1H-indole-3-carboxamide) deriv. 10m	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4028&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328604	8033722		CHEMBL61278			C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5996	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(ccc3n2C)C#N)c(C(=O)Nc2ccccc2)c2cc(ccc12)C#N	InChI=1S/C34H24N6O2S2/c1-39-27-15-13-21(19-35)17-25(27)29(31(41)37-23-9-5-3-6-10-23)33(39)43-44-34-30(32(42)38-24-11-7-4-8-12-24)26-18-22(20-36)14-16-28(26)40(34)2/h3-18H,1-2H3,(H,37,41)(H,38,42)	MJGOASKYDRKUGY-UHFFFAOYSA-N	4029	5-cyano-2-{[5-cyano-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10n	Epidermal growth factor receptor	Homo sapiens		 54100  							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4029	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4029&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328605	8033723					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5997	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(ccc3n2C)[N+]([O-])=O)c(C(=O)Nc2ccccc2)c2cc(ccc12)[N+]([O-])=O	InChI=1S/C32H24N6O6S2/c1-35-25-15-13-21(37(41)42)17-23(25)27(29(39)33-19-9-5-3-6-10-19)31(35)45-46-32-28(30(40)34-20-11-7-4-8-12-20)24-18-22(38(43)44)14-16-26(24)36(32)2/h3-18H,1-2H3,(H,33,39)(H,34,40)	MGEHDKGYSLPVOE-UHFFFAOYSA-N	4030	1-methyl-2-{[1-methyl-5-nitro-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-5-nitro-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10o	Epidermal growth factor receptor	Homo sapiens		 5000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4030&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328606	8033724					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5998	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3ccc(Cl)cc3n2C)c(C(=O)Nc2ccccc2)c2ccc(Cl)cc12	InChI=1S/C32H24Cl2N4O2S2/c1-37-25-17-19(33)13-15-23(25)27(29(39)35-21-9-5-3-6-10-21)31(37)41-42-32-28(30(40)36-22-11-7-4-8-12-22)24-16-14-20(34)18-26(24)38(32)2/h3-18H,1-2H3,(H,35,39)(H,36,40)	MDHSVFAJRLCBEE-UHFFFAOYSA-N	4031	6-chloro-2-{[6-chloro-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10p	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4031&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328607	8033725					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
5999	Cc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(C)cc4n3C)n(C)c2c1	InChI=1S/C34H30N4O2S2/c1-21-15-17-25-27(19-21)37(3)33(29(25)31(39)35-23-11-7-5-8-12-23)41-42-34-30(32(40)36-24-13-9-6-10-14-24)26-18-16-22(2)20-28(26)38(34)4/h5-20H,1-4H3,(H,35,39)(H,36,40)	RIWLLXKPZKILLE-UHFFFAOYSA-N	4032	2-{[1,6-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1,6-dimethyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10q	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4032&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328608	8033726					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6000	COc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(OC)cc4n3C)n(C)c2c1	InChI=1S/C34H30N4O4S2/c1-37-27-19-23(41-3)15-17-25(27)29(31(39)35-21-11-7-5-8-12-21)33(37)43-44-34-30(32(40)36-22-13-9-6-10-14-22)26-18-16-24(42-4)20-28(26)38(34)2/h5-20H,1-4H3,(H,35,39)(H,36,40)	RDOOVEMEWGTJTD-UHFFFAOYSA-N	4033	6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10r	Epidermal growth factor receptor	Homo sapiens		 3600							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4033&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328609	8033727					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6001	CC(=O)Oc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(OC(C)=O)cc4n3C)n(C)c2c1	InChI=1S/C36H30N4O6S2/c1-21(41)45-25-15-17-27-29(19-25)39(3)35(31(27)33(43)37-23-11-7-5-8-12-23)47-48-36-32(34(44)38-24-13-9-6-10-14-24)28-18-16-26(46-22(2)42)20-30(28)40(36)4/h5-20H,1-4H3,(H,37,43)(H,38,44)	YEPYWZKAUTZXSJ-UHFFFAOYSA-N	4034	2-{[6-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-3-(phenylcarbamoyl)-1H-indol-6-yl acetate::dithiobis(1H-indole-3-carboxamide) deriv. 10s	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4034	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4034&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328610	8033728					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6002	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3ccc(O)cc3n2C)c(C(=O)Nc2ccccc2)c2ccc(O)cc12	InChI=1S/C32H26N4O4S2/c1-35-25-17-21(37)13-15-23(25)27(29(39)33-19-9-5-3-6-10-19)31(35)41-42-32-28(30(40)34-20-11-7-4-8-12-20)24-16-14-22(38)18-26(24)36(32)2/h3-18,37-38H,1-2H3,(H,33,39)(H,34,40)	KGVFYDBDTHRCJU-UHFFFAOYSA-N	4035	6-hydroxy-2-{[6-hydroxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10t	Epidermal growth factor receptor	Homo sapiens		 44000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4035&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328611	8033729					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6003	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cccc(Cl)c3n2C)c(C(=O)Nc2ccccc2)c2cccc(Cl)c12	InChI=1S/C32H24Cl2N4O2S2/c1-37-27-21(15-9-17-23(27)33)25(29(39)35-19-11-5-3-6-12-19)31(37)41-42-32-26(30(40)36-20-13-7-4-8-14-20)22-16-10-18-24(34)28(22)38(32)2/h3-18H,1-2H3,(H,35,39)(H,36,40)	XXZKVHUDQGDVAB-UHFFFAOYSA-N	4036	7-chloro-2-{[7-chloro-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10u	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4036&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328612	8033730					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6004	Cc1cccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4cccc(C)c4n3C)n(C)c12	InChI=1S/C34H30N4O2S2/c1-21-13-11-19-25-27(31(39)35-23-15-7-5-8-16-23)33(37(3)29(21)25)41-42-34-28(32(40)36-24-17-9-6-10-18-24)26-20-12-14-22(2)30(26)38(34)4/h5-20H,1-4H3,(H,35,39)(H,36,40)	YZZFXHMKRBCTSB-UHFFFAOYSA-N	4037	2-{[1,7-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1,7-dimethyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10v	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4037&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328613	8033731					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6016	COc1cccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4cccc(OC)c4n3C)n(C)c12	InChI=1S/C34H30N4O4S2/c1-37-29-23(17-11-19-25(29)41-3)27(31(39)35-21-13-7-5-8-14-21)33(37)43-44-34-28(32(40)36-22-15-9-6-10-16-22)24-18-12-20-26(42-4)30(24)38(34)2/h5-20H,1-4H3,(H,35,39)(H,36,40)	AHAJMDDSMVHMGD-UHFFFAOYSA-N	4038	7-methoxy-2-{[7-methoxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10w	Epidermal growth factor receptor	Homo sapiens		 6500							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4038	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4038&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328614	8033732					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6017	CC(=O)Oc1cccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4cccc(OC(C)=O)c4n3C)n(C)c12	InChI=1S/C36H30N4O6S2/c1-21(41)45-27-19-11-17-25-29(33(43)37-23-13-7-5-8-14-23)35(39(3)31(25)27)47-48-36-30(34(44)38-24-15-9-6-10-16-24)26-18-12-20-28(46-22(2)42)32(26)40(36)4/h5-20H,1-4H3,(H,37,43)(H,38,44)	LJJMQOMCMBZYNH-UHFFFAOYSA-N	4039	2-{[7-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-3-(phenylcarbamoyl)-1H-indol-7-yl acetate::dithiobis(1H-indole-3-carboxamide) deriv. 10x	Epidermal growth factor receptor	Homo sapiens		 9900							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4039&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328615	8033733					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6018	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cccc(O)c3n2C)c(C(=O)Nc2ccccc2)c2cccc(O)c12	InChI=1S/C32H26N4O4S2/c1-35-27-21(15-9-17-23(27)37)25(29(39)33-19-11-5-3-6-12-19)31(35)41-42-32-26(30(40)34-20-13-7-4-8-14-20)22-16-10-18-24(38)28(22)36(32)2/h3-18,37-38H,1-2H3,(H,33,39)(H,34,40)	DVIOTQVUWWUVNL-UHFFFAOYSA-N	4040	7-hydroxy-2-{[7-hydroxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10y	Epidermal growth factor receptor	Homo sapiens		 100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4040	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4040&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328616	8033734					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6019	Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cccnc3n2C)c(C(=O)Nc2ccccc2)c2cccnc12	InChI=1S/C30H24N6O2S2/c1-35-25-21(15-9-17-31-25)23(27(37)33-19-11-5-3-6-12-19)29(35)39-40-30-24(22-16-10-18-32-26(22)36(30)2)28(38)34-20-13-7-4-8-14-20/h3-18H,1-2H3,(H,33,37)(H,34,38)	HCTZFBVISJHBHE-UHFFFAOYSA-N	4041	1-methyl-2-{[1-methyl-3-(phenylcarbamoyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]disulfanyl}-N-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide::2,2 -dithiobis(l,3-dihydro-1-methyl-N-phenyl-2H-pyrrolo[2,3-b]pyridme-3-carboxde)::dithiobis(1H-indole-3-carboxamide) deriv. 10z	Epidermal growth factor receptor	Homo sapiens		 22300							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4041&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328617	8033735					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6020	CN1C(=S)C(C(=O)Nc2ccccc2)c2ccccc12	InChI=1S/C16H14N2OS/c1-18-13-10-6-5-9-12(13)14(16(18)20)15(19)17-11-7-3-2-4-8-11/h2-10,14H,1H3,(H,17,19)	PMQPQXPWWRMDGF-UHFFFAOYSA-N	4042	2,3-dihydro-1-methyl-N-phenyl-2-thioxo-2H-indole-3-carboxamide::1-methyl-N-phenyl-2-sulfanylidene-2,3-dihydro-1H-indole-3-carboxamide::2-thioxo-1H-indole-3-carboxamide deriv. 9a	Epidermal growth factor receptor	Homo sapiens		 1000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4042&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328618	8033736							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6021	CN1C(=S)C(C(=O)Nc2ccccc2)c2cc(Cl)ccc12	InChI=1S/C16H13ClN2OS/c1-19-13-8-7-10(17)9-12(13)14(16(19)21)15(20)18-11-5-3-2-4-6-11/h2-9,14H,1H3,(H,18,20)	LKNJAWRXHXSFKQ-UHFFFAOYSA-N	4043	5-chloro-1-methyl-N-phenyl-2-sulfanylidene-2,3-dihydro-1H-indole-3-carboxamide::2-thioxo-1H-indole-3-carboxamide deriv. 9g	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4043	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4043&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328619	8033737							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6022	CN1C(=S)C(C(=O)Nc2ccccc2)c2cccnc12	InChI=1S/C15H13N3OS/c1-18-13-11(8-5-9-16-13)12(15(18)20)14(19)17-10-6-3-2-4-7-10/h2-9,12H,1H3,(H,17,19)	XSWFYMGWWIUBBO-UHFFFAOYSA-N	4044	1-methyl-N-phenyl-2-sulfanylidene-1H,2H,3H-pyrrolo[2,3-b]pyridine-3-carboxamide::1,3-dihydro-1-methyl-N-phenyl-2-thioxo-2H-pyrrolo[2,3-b]pyridine-3-carboxamide::2-thioxo-1H-indole-3-carboxamide deriv. 9z	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4044	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4044&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328620	8033738							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6023	CN1C(=S)C(C)(C(=O)Nc2ccccc2)c2ccccc12	InChI=1S/C17H16N2OS/c1-17(15(20)18-12-8-4-3-5-9-12)13-10-6-7-11-14(13)19(2)16(17)21/h3-11H,1-2H3,(H,18,20)	RIAZXZRDAZBVMK-UHFFFAOYSA-N	4045	1,3-dimethyl-N-phenyl-2-sulfanylidene-2,3-dihydro-1H-indole-3-carboxamide::1,3-dimethyl-N-phenyl-2-thioxoindoline-3-carboxamide::2-thioxo-1H-indole-3-carboxamide deriv. 11	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4045	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4045&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328621	8033739							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6024	CSc1c(C(=O)Nc2ccccc2)c2ccccc2n1C	InChI=1S/C17H16N2OS/c1-19-14-11-7-6-10-13(14)15(17(19)21-2)16(20)18-12-8-4-3-5-9-12/h3-11H,1-2H3,(H,18,20)	NSWAGYPTXMCALG-UHFFFAOYSA-N	4046	1-Methyl-2-(methylthio)-N-phenyl-1H-indole-3-carboxamide::1-methyl-2-(methylsulfanyl)-N-phenyl-1H-indole-3-carboxamide::2-thioxo-1H-indole-3-carboxamide deriv. 12	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4046&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328622	8033740							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6025	Cn1c(SSc2ccccc2)c(C(=O)Nc2ccccc2)c2ccccc12	InChI=1S/C22H18N2OS2/c1-24-19-15-9-8-14-18(19)20(21(25)23-16-10-4-2-5-11-16)22(24)27-26-17-12-6-3-7-13-17/h2-15H,1H3,(H,23,25)	ULDPDJYUQOVMMM-UHFFFAOYSA-N	4047	1-methyl-N-phenyl-2-(phenyldisulfanyl)-1H-indole-3-carboxamide::l-Methyl-N-phenyl-2-(phenyldithio)-1H-indole-3-carboxamide::2-thioxo-1H-indole-3-carboxamide deriv. 13	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4047&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328623	8033741					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6026	Cn1c(SSCc2ccccc2)c(C(=O)Nc2ccccc2)c2ccccc12	InChI=1S/C23H20N2OS2/c1-25-20-15-9-8-14-19(20)21(22(26)24-18-12-6-3-7-13-18)23(25)28-27-16-17-10-4-2-5-11-17/h2-15H,16H2,1H3,(H,24,26)	KFXYCDPZWVGSPZ-UHFFFAOYSA-N	4048	2-(benzyldisulfanyl)-1-methyl-N-phenyl-1H-indole-3-carboxamide::2-(Benzyldithio)-1-methyl-N-phenyl-1H-indole-3-carboxamide::2-thioxo-1H-indole-3-carboxamide deriv. 14	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm00039a016	10.7270/Q2H41PMC	8027985	aid1795591		Rewcastle, GW; Palmer, BD; Dobrusin, EM; Fry, DW; Kraker, AJ; Denny, WA	6/24/1994	4/20/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4048&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328624	8033742					C15496		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6457	N#C\[#6](=[#6]/c1cccnc1)C#N	InChI=1S/C9H4N3/c10-5-9(6-11)4-8-2-1-3-12-7-8/h1-3,7H	UANDWZJJNXWUOF-UHFFFAOYSA-N	4271	2-(pyridin-3-ylmethylidene)propanedinitrile::Tyrphostin deriv. 1	Epidermal growth factor receptor	Homo sapiens		 225000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4271	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4271&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23905	8033948							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6458	[O-]S(=O)(=O)c1ccc(C=C(C#N)C#N)o1	InChI=1S/C8H4N2O4S/c9-4-6(5-10)3-7-1-2-8(14-7)15(11,12)13/h1-3H,(H,11,12,13)/p-1	LLPRRMGWDXUHKP-UHFFFAOYSA-M	4272	sodium 5-(2,2-dicyanoeth-1-en-1-yl)furan-2-sulfonate::(5-Sulfofurfural)Sodium Salt::Tyrphostin deriv. 2	Epidermal growth factor receptor	Homo sapiens		>250000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4272	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4272&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895605	8033949							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6459	[#6]-[#6](=O)-[#7]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C12H4N3O/c1-9(16)15-12-4-2-10(3-5-12)6-11(7-13)8-14/h2-5H	CTVKWABYXLZVGC-UHFFFAOYSA-N	4273	N-[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]acetamide::Tyrphostin deriv. 3	Epidermal growth factor receptor	Homo sapiens		>325000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4273	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4273&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			33296	8033950							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6460	N#CC(=Cc1ncc[nH]1)C#N |(12.23,-11.09,;12.26,-9.41,;12.28,-7.72,;10.94,-6.96,;9.35,-7.62,;8.87,-6.15,;7.33,-6.16,;6.86,-7.62,;8.11,-8.52,;13.61,-6.93,;14.93,-6.15,)|	InChI=1S/C7H4N4/c8-4-6(5-9)3-7-10-1-2-11-7/h1-3H,(H,10,11)	AYENSJBDZMHPTB-UHFFFAOYSA-N	4274	2-(1H-imidazol-2-ylmethylidene)propanedinitrile::Tyrphostin deriv. 4	Epidermal growth factor receptor	Homo sapiens		 532000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4274	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4274&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328746	8033951							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6461	[#6]-[#16]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C11H4N2S/c1-14-11-4-2-9(3-5-11)6-10(7-12)8-13/h2-5H	CWBMWSAMPGILNT-UHFFFAOYSA-N	4275	2-{[4-(methylsulfanyl)phenyl]methylidene}propanedinitrile::Tyrphostin deriv. 5	Epidermal growth factor receptor	Homo sapiens		>625000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4275	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4275&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			710163	8033952							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6462	[#6]-[#8]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1F	InChI=1S/C11H3FN2O/c1-15-11-3-2-8(5-10(11)12)4-9(6-13)7-14/h2-3,5H	PFPLDFAUOJPYDQ-UHFFFAOYSA-N	4276	2-[(3-fluoro-4-methoxyphenyl)methylidene]propanedinitrile::Tyrphostin deriv. 6	Epidermal growth factor receptor	Homo sapiens		 800000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4276	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4276&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328747	8033953							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6463	N=C(C(C#N)C#N)C(=Cc1ccc2[nH]ccc2c1)C#N |w:8.8|	InChI=1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,13,19-20H	PEBPSCWSXYPIJD-UHFFFAOYSA-N	4277	(3Z)-2-amino-3-(1H-indol-5-ylmethylidene)prop-1-ene-1,1,3-tricarbonitrile::Indole-Containing Inhibitor 2::Tyrphostin deriv. 7	Epidermal growth factor receptor	Homo sapiens		 820000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4277	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4277&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895606	8033954							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6464	N#C\[#6](=[#6]/c1ccco1)C#N	InChI=1S/C8H3N2O/c9-5-7(6-10)4-8-2-1-3-11-8/h1-3H	SHOCFKOAKLWGNK-UHFFFAOYSA-N	4278	2-(furan-2-ylmethylidene)propanedinitrile::Tyrphostin deriv. 8	Epidermal growth factor receptor	Homo sapiens		>1250000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4278	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4278&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			18606	8033955							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6465	N#C\[#6](=[#6]/c1ccc(cc1)C#N)C#N	InChI=1S/C11H4N3/c12-6-10-3-1-9(2-4-10)5-11(7-13)8-14/h1-4H	AIBCNVVSNMPGGP-UHFFFAOYSA-N	4279	2-[(4-cyanophenyl)methylidene]propanedinitrile::Tyrphostin deriv. 10	Epidermal growth factor receptor	Homo sapiens		 1400000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4279	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4279&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			37583	8033956							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6466	N#CC(=Cc1ccn[nH]1)C#N |(14.9,-11.28,;14.93,-9.6,;14.95,-7.91,;13.61,-7.16,;12.2,-7.71,;11.72,-6.24,;10.18,-6.24,;9.7,-7.71,;10.95,-8.61,;16.28,-7.12,;17.6,-6.34,)|	InChI=1S/C7H4N4/c8-4-6(5-9)3-7-1-2-10-11-7/h1-3H,(H,10,11)	UBHAOBPYJHLFBZ-UHFFFAOYSA-N	4280	2-(1H-pyrazol-5-ylmethylidene)propanedinitrile::Tyrphostin deriv. 11	Epidermal growth factor receptor	Homo sapiens		 1480000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4280	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4280&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328749	8033957							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6467	[#6]S(=O)c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C11H4N2OS/c1-15(14)11-4-2-9(3-5-11)6-10(7-12)8-13/h2-5H	BOYLCHZUKPQMER-UHFFFAOYSA-N	4281	[4-(Methylsulfinyl)Benzylidene]malononitrile::2-[(4-methanesulfinylphenyl)methylidene]propanedinitrile::Tyrphostin deriv. 12	Epidermal growth factor receptor	Homo sapiens		 1800000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4281	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4281&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328750	8033958							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6468	N#CC(=Cc1ccc2[nH]ccc2c1)C#N |(14.9,-11.28,;14.93,-9.6,;14.95,-7.91,;13.61,-7.16,;12.28,-7.94,;12.28,-9.48,;10.95,-10.25,;9.62,-9.48,;8.15,-9.96,;7.25,-8.71,;8.15,-7.47,;9.62,-7.94,;10.95,-7.17,;16.28,-7.12,;17.6,-6.34,)|	InChI=1S/C12H7N3/c13-7-10(8-14)5-9-1-2-12-11(6-9)3-4-15-12/h1-6,15H	WXKRFPWLMFBHAV-UHFFFAOYSA-N	4282	2-(1H-indol-5-ylmethylidene)propanedinitrile::Tyrphostin deriv. 13	Epidermal growth factor receptor	Homo sapiens		 2200000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4282	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4282&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328751	8033959							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6469	N#C\[#6](=[#6]/c1ccc2-[#7](-[#6]-c3ccccc3)-[#6]-[#6]-c2c1)C#N	InChI=1S/C19H8N3/c20-12-17(13-21)10-16-6-7-19-18(11-16)8-9-22(19)14-15-4-2-1-3-5-15/h1-7,11H	HBFWMJXLOHWKFL-UHFFFAOYSA-N	4283	[(N-Benzyl-5-indolinyl)methylene)]malononitrile::2-[(1-benzyl-2,3-dihydro-1H-indol-5-yl)methylidene]propanedinitrile::Tyrphostin deriv. 14	Epidermal growth factor receptor	Homo sapiens		>2500000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4283	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4283&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328752	8033960							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6470	[#8]-c1cc2-[#6]-[#6]\[#6](=[#6](\C#N)C#N)-c2cc1-[#8]	InChI=1S/C12H2N2O2/c13-5-8(6-14)9-2-1-7-3-11(15)12(16)4-10(7)9/h3-4H	YBKLQRYOHYTACJ-UHFFFAOYSA-N	4284	2-(5,6-dihydroxy-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile::(5,6-Dihydroxyindanylidene)malononitrile::Tyrphostin deriv. 15	Epidermal growth factor receptor	Homo sapiens		 500					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4284	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4284&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328753	8033961							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6471	[#8]-c1cc2-[#7]-[#6](=O)\[#6](=[#6](\C#N)C#N)-c2cc1-[#8]	InChI=1S/C11H2N3O3/c12-3-5(4-13)10-6-1-8(15)9(16)2-7(6)14-11(10)17/h1-2H	AXLZKLXUIVMYGD-UHFFFAOYSA-N	4285	2-(5,6-dihydroxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile::(5,6-Dihydroxy-2-oxo-3-indolinidene)malononitrile::Tyrphostin deriv. 16	Epidermal growth factor receptor	Homo sapiens		 2500					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4285	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4285&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328754	8033962							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6472	[#8]-c1ccc2\[#6](-[#6]-[#6]-c2c1-[#8])=[#6](/C#N)C#N	InChI=1S/C12H2N2O2/c13-5-7(6-14)8-1-2-10-9(8)3-4-11(15)12(10)16/h3-4H	BTRFAZLTYSJCJI-UHFFFAOYSA-N	4286	2-(4,5-dihydroxy-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile::(4,5-Dihydroxyindanylidene)malononitrile::Tyrphostin deriv. 17	Epidermal growth factor receptor	Homo sapiens		 7000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4286	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4286&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328755	8033963							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6473	[#8]-c1ccc2-[#7]-[#6](=O)\[#6](=[#6](\C#N)C#N)-c2c1	InChI=1S/C11H3N3O2/c12-4-6(5-13)10-8-3-7(15)1-2-9(8)14-11(10)16/h1-3H	YZBJHSIXKLAEJP-UHFFFAOYSA-N	4287	2-(5-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile::(5-Hydroxy-2-oxo-3-indolinidene)malononitrile::Tyrphostin deriv. 18	Epidermal growth factor receptor	Homo sapiens		 12500							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4287	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4287&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328756	8033964							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6474	[#6]-[#7]-1-[#6](=O)\[#6](=[#6](\C#N)C#N)-c2cc(-[#8])ccc-12	InChI=1S/C12H3N3O2/c1-15-10-3-2-8(16)4-9(10)11(12(15)17)7(5-13)6-14/h2-4H	CULRJSQRBRCGCG-UHFFFAOYSA-N	4288	2-(5-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile::(N-Methyl-5-hydroxy-2-oxo-3-indolinidene)malononitrile::Tyrphostin deriv. 19	Epidermal growth factor receptor	Homo sapiens		 26000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4288	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4288&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328757	8033965							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6475	[#8-]-[#7+](=O)-c1ccc2-[#7]-[#6](=O)\[#6](=[#6](\C#N)C#N)-c2c1	InChI=1S/C11H3N4O3/c12-4-6(5-13)10-8-3-7(15(17)18)1-2-9(8)14-11(10)16/h1-3H	UBEMOCBYNCVVEE-UHFFFAOYSA-N	4289	2-(5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile::Tyrphostin deriv. 20	Epidermal growth factor receptor	Homo sapiens		 40000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4289	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4289&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3374314	8033966							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6476	[#6]-[#8]-c1cc2\[#6](=[#6](/C#N)C#N)-[#6](=O)-[#7]-c2cc1-[#8]	InChI=1S/C12H2N3O3/c1-18-10-2-7-8(3-9(10)16)15-12(17)11(7)6(4-13)5-14/h2-3H	IHXAKYWIIMTFPX-UHFFFAOYSA-N	4290	(5-Methoxy-6-hydroxy-2-oxo-3-indolinidene)malononitrile::2-(6-hydroxy-5-methoxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile::Tyrphostin deriv. 21	Epidermal growth factor receptor	Homo sapiens		 60000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4290	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4290&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328758	8033967							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6477	O=[#6]1-[#7]-c2ccccc2\[#6]-1=[#6](/C#N)C#N	InChI=1S/C11H4N3O/c12-5-7(6-13)10-8-3-1-2-4-9(8)14-11(10)15/h1-4H	PDDXPZIQCBVGRY-UHFFFAOYSA-N	4291	CHEMBL293798::(2-Oxo-3-indolinidene)malononitrile::2-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile::Tyrphostin deriv. 22	Epidermal growth factor receptor	Homo sapiens		>250000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4291	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4291&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			244537	8033968		CHEMBL293798					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6478	[#8]-c1cccc2\[#6](-[#6]-[#6]-[#6]-c12)=[#6](/C#N)C#N	InChI=1S/C13H3N2O/c14-7-9(8-15)10-3-1-5-12-11(10)4-2-6-13(12)16/h2,4,6H	XTSGEFHXZVLNOC-UHFFFAOYSA-N	4292	2-(5-hydroxy-1,2,3,4-tetrahydronaphthalen-1-ylidene)propanedinitrile::Tyrphostin deriv. 23	Epidermal growth factor receptor	Homo sapiens		 1200000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4292	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4292&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328759	8033969							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6479	Oc1ccc(\C=C(/C#N)C(=O)c2ccc(O)c(O)c2)cc1O	InChI=1S/C16H11NO5/c17-8-11(5-9-1-3-12(18)14(20)6-9)16(22)10-2-4-13(19)15(21)7-10/h1-7,18-21H	CANOJKGQDCJDOX-UHFFFAOYSA-N	4293	(2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphenyl)carbonyl]prop-2-enenitrile::cid_5328760::3,4-Dihydroxy-a-(3,4-dihydroxybenzoyl)-cis-cinnamonitrile 2-Cyano-3 ,4 -dihydroxyacetophenone::Tyrphostin deriv. 24	Epidermal growth factor receptor	Homo sapiens		 370							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4293	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4293&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328760	8033970							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6480	Oc1ccc(\C=C(/C#N)C(=O)c2ccc(F)cc2)cc1O	InChI=1S/C16H10FNO3/c17-13-4-2-11(3-5-13)16(21)12(9-18)7-10-1-6-14(19)15(20)8-10/h1-8,19-20H	ALUHXQXQTNRXQL-UHFFFAOYSA-N	4294	(2E)-3-(3,4-dihydroxyphenyl)-2-[(4-fluorophenyl)carbonyl]prop-2-enenitrile::3,4-Dihydroxy-a-(p-fluorobenzoyl)-cis-cinnamonitrile::Tyrphostin deriv. 25	Epidermal growth factor receptor	Homo sapiens		 560							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328761	8033971							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6481	Cc1ccc(cc1)C(=O)C(=C\c1ccc(O)c(O)c1)\C#N	InChI=1S/C17H13NO3/c1-11-2-5-13(6-3-11)17(21)14(10-18)8-12-4-7-15(19)16(20)9-12/h2-9,19-20H,1H3	ZALNJTCOAIAQFA-UHFFFAOYSA-N	4295	(2E)-3-(3,4-dihydroxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enenitrile::Tyrphostin deriv. 28	Epidermal growth factor receptor	Homo sapiens		 880							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4295	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4295&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328762	8033972							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6482	Oc1ccc(\C=C(/C#N)C(=O)c2ccccc2)cc1O	InChI=1S/C16H11NO3/c17-10-13(16(20)12-4-2-1-3-5-12)8-11-6-7-14(18)15(19)9-11/h1-9,18-19H	QBKFKKGORMOFFU-UHFFFAOYSA-N	4296	(2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Tyrphostin deriv. 29	Epidermal growth factor receptor	Homo sapiens		 1300							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4296	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4296&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328763	8033973							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6483	Oc1ccc(\C=C(/C#N)C(=O)c2ccccc2Cl)cc1O	InChI=1S/C16H10ClNO3/c17-13-4-2-1-3-12(13)16(21)11(9-18)7-10-5-6-14(19)15(20)8-10/h1-8,19-20H	JVRJGQNWQLITMA-UHFFFAOYSA-N	4297	(2E)-2-[(2-chlorophenyl)carbonyl]-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Tyrphostin deriv. 30	Epidermal growth factor receptor	Homo sapiens		 1540							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4297	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4297&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328764	8033974							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6484	Oc1ccc(\C=C(/C#N)C(=O)c2ccc(cc2)[N+]([O-])=O)cc1O	InChI=1S/C16H10N2O5/c17-9-12(7-10-1-6-14(19)15(20)8-10)16(21)11-2-4-13(5-3-11)18(22)23/h1-8,19-20H	WSDDCSPJUMHQSE-UHFFFAOYSA-N	4298	(2E)-3-(3,4-dihydroxyphenyl)-2-[(4-nitrophenyl)carbonyl]prop-2-enenitrile::Tyrphostin deriv. 33	Epidermal growth factor receptor	Homo sapiens		 2300							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4298	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4298&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328765	8033975							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6485	Oc1ccc(\C=C(/C#N)C(=O)c2cccs2)cc1O	InChI=1S/C14H9NO3S/c15-8-10(14(18)13-2-1-5-19-13)6-9-3-4-11(16)12(17)7-9/h1-7,16-17H	CPXCUSISXFTYFB-UHFFFAOYSA-N	4299	CHEMBL55994::(2E)-3-(3,4-dihydroxyphenyl)-2-(thiophen-2-ylcarbonyl)prop-2-enenitrile::Tyrphostin deriv. 36	Epidermal growth factor receptor	Homo sapiens		 3100							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4299	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4299&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328766	8033976		CHEMBL55994					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6486	Cc1cc(C)c(C(=O)C(=Cc2ccc(O)c(O)c2)C#N)c(C)c1 |w:9.9|	InChI=1S/C19H17NO3/c1-11-6-12(2)18(13(3)7-11)19(23)15(10-20)8-14-4-5-16(21)17(22)9-14/h4-9,21-22H,1-3H3	CVJUVNFCJFFASS-UHFFFAOYSA-N	4300	(2E)-3-(3,4-dihydroxyphenyl)-2-[(2,4,6-trimethylphenyl)carbonyl]prop-2-enenitrile::Tyrphostin deriv. 39	Epidermal growth factor receptor	Homo sapiens		 10700							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4300	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328767	8033977							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6487	c1cc(c(cc1/C=C(\C#N)/C(=O)N)O)O	InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)	USOXQZNJFMKTKJ-UHFFFAOYSA-N	4301	(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide::CHEMBL296407::benzylidenemalononitrile (BMN) deriv. 46::Tyrphostin deriv. 40	Epidermal growth factor receptor	Homo sapiens		 10000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4301	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4301&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	JGB	6QS5	5328768	8033978		CHEMBL296407					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6488	C[C@@H](NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)c1ccccc1 |r|	InChI=1S/C18H16N2O3/c1-12(14-5-3-2-4-6-14)20-18(23)15(11-19)9-13-7-8-16(21)17(22)10-13/h2-10,12,21-22H,1H3,(H,20,23)	UMGQVUWXNOJOSJ-UHFFFAOYSA-N	4302	cid_5328772::(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]prop-2-enamide::Tyrphostin deriv. 44	Epidermal growth factor receptor	Homo sapiens		 400							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4302	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4302&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328772	8033979							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6489	Oc1ccc(\C=C(/C#N)C(=O)NCCCc2ccccc2)cc1O	InChI=1S/C19H18N2O3/c20-13-16(11-15-8-9-17(22)18(23)12-15)19(24)21-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,22-23H,4,7,10H2,(H,21,24)	GSQOBTOAOGXIFL-UHFFFAOYSA-N	4303	MLS000069704::(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide::cid_5328770::TYRPHOSTIN AG 555::CHEMBL53898::(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide::SMR000058519::(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide::(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)acrylamide::(E)-3-[3,4-bis(oxidanyl)phenyl]-2-cyano-N-(3-phenylpropyl)prop-2-enamide::Tyrphostin deriv. 46	Epidermal growth factor receptor	Homo sapiens		 700							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4303	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4303&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328770	8033980		CHEMBL53898					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6490	Oc1ccc(\C=C(/C#N)C(=O)Nc2ccccc2)cc1O	InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)	HKHOVJYOELRGMV-UHFFFAOYSA-N	4304	cid_5328771::CHEMBL56731::(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide::tyrphostin 1	Epidermal growth factor receptor	Homo sapiens		 700							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4304	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4304&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328771	8033981		CHEMBL56731					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6491	C[C@H](NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)c1ccccc1 |r|	InChI=1S/C18H16N2O3/c1-12(14-5-3-2-4-6-14)20-18(23)15(11-19)9-13-7-8-16(21)17(22)10-13/h2-10,12,21-22H,1H3,(H,20,23)	UMGQVUWXNOJOSJ-UHFFFAOYSA-N	4305	(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide::Tyrphostin deriv. 50	Epidermal growth factor receptor	Homo sapiens		 860							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4305	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4305&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328769	8033982							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6492	Oc1ccc(\C=C(/C#N)C(=O)NCCc2ccccc2)cc1O	InChI=1S/C18H16N2O3/c19-12-15(10-14-6-7-16(21)17(22)11-14)18(23)20-9-8-13-4-2-1-3-5-13/h1-7,10-11,21-22H,8-9H2,(H,20,23)	ZZQHNBGRWRQWFI-UHFFFAOYSA-N	4306	CHEMBL293749::(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide::Tyrphostin deriv. 52	Epidermal growth factor receptor	Homo sapiens		 930							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4306	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4306&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328773	8033983		CHEMBL293749					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6493	Oc1ccc(\C=C(/C#N)C(=O)Nc2ccccc2Cl)cc1O	InChI=1S/C16H11ClN2O3/c17-12-3-1-2-4-13(12)19-16(22)11(9-18)7-10-5-6-14(20)15(21)8-10/h1-8,20-21H,(H,19,22)	NJPHTBIXEKQNKZ-UHFFFAOYSA-N	4307	(2E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide::Tyrphostin deriv. 54	Epidermal growth factor receptor	Homo sapiens		 1100							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4307	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4307&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328774	8033984							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6494	Oc1ccc(\C=C(/C#N)C(=O)NCCCCc2ccccc2)cc1O	InChI=1S/C20H20N2O3/c21-14-17(12-16-9-10-18(23)19(24)13-16)20(25)22-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,23-24H,4-5,8,11H2,(H,22,25)	GWCNJMUSWLTSCW-UHFFFAOYSA-N	4308	CHEMBL440298::(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide::Tyrphostin deriv. 56	Epidermal growth factor receptor	Homo sapiens		 1100							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4308	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4308&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328775	8033985		CHEMBL440298					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6495	CCOC(=O)C(Cc1ccccc1)NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N	InChI=1S/C21H20N2O5/c1-2-28-21(27)17(11-14-6-4-3-5-7-14)23-20(26)16(13-22)10-15-8-9-18(24)19(25)12-15/h3-10,12,17,24-25H,2,11H2,1H3,(H,23,26)	IZNDRNBAQQZJSB-UHFFFAOYSA-N	4309	ethyl 2-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]-3-phenylpropanoate::Tyrphostin deriv. 58	Epidermal growth factor receptor	Homo sapiens		 1530							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328776	8033986							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6496	Oc1ccc(\C=C(/C#N)C(=O)NC2CCCCC2)cc1O	InChI=1S/C16H18N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h6-9,13,19-20H,1-5H2,(H,18,21)	XMFXBOGXTNAKKW-UHFFFAOYSA-N	4310	(2E)-2-cyano-N-cyclohexyl-3-(3,4-dihydroxyphenyl)prop-2-enamide::Tyrphostin deriv. 60	Epidermal growth factor receptor	Homo sapiens		 1600							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4310	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4310&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2385464	8033987							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6497	COc1ccc(CCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1OC	InChI=1S/C20H20N2O5/c1-26-18-6-4-13(11-19(18)27-2)7-8-22-20(25)15(12-21)9-14-3-5-16(23)17(24)10-14/h3-6,9-11,23-24H,7-8H2,1-2H3,(H,22,25)	SPPRJVVDZRWCNP-UHFFFAOYSA-N	4311	(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide::Tyrphostin deriv. 62	Epidermal growth factor receptor	Homo sapiens		 1700							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4311	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4311&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328777	8033988							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6498	COc1ccc(NC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)c(OC)c1	InChI=1S/C18H16N2O5/c1-24-13-4-5-14(17(9-13)25-2)20-18(23)12(10-19)7-11-3-6-15(21)16(22)8-11/h3-9,21-22H,1-2H3,(H,20,23)	CSHGVUBBAZPQSJ-UHFFFAOYSA-N	4312	(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2,4-dimethoxyphenyl)prop-2-enamide::Tyrphostin deriv. 64	Epidermal growth factor receptor	Homo sapiens		 1700							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328778	8033989							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6499	Oc1ccc(\C=C(/C#N)C(=O)NCc2ccccc2)cc1O	InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)	TUCIOBMMDDOEMM-UHFFFAOYSA-N	4313	CHEMBL56543::(2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide::Tyrphostin deriv. 42::AG-490::Tyrphostin B42::Tyrphostin AG 490::AG 490	Epidermal growth factor receptor	Homo sapiens		 2000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4313	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4313&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328779	8033990		CHEMBL56543					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6500	Oc1ccc(\C=C(/C#N)C(=O)N2CCc3ccccc23)cc1O	InChI=1S/C18H14N2O3/c19-11-14(9-12-5-6-16(21)17(22)10-12)18(23)20-8-7-13-3-1-2-4-15(13)20/h1-6,9-10,21-22H,7-8H2	MYKCTDWWIWGLHW-UHFFFAOYSA-N	4314	cid_1838043::(2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Tyrphostin deriv. 66	Epidermal growth factor receptor	Homo sapiens		 2100							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4314	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4314&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1838043	8033991							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6501	Oc1ccc(\C=C(/C#N)C(=O)N2CCN(CC2)c2ccccc2)cc1O	InChI=1S/C20H19N3O3/c21-14-16(12-15-6-7-18(24)19(25)13-15)20(26)23-10-8-22(9-11-23)17-4-2-1-3-5-17/h1-7,12-13,24-25H,8-11H2	LKHXJJMDMFKAPD-UHFFFAOYSA-N	4315	(2E)-3-(3,4-dihydroxyphenyl)-2-[(4-phenylpiperazin-1-yl)carbonyl]prop-2-enenitrile::Tyrphostin deriv. 68	Epidermal growth factor receptor	Homo sapiens		 4300							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4315	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4315&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328780	8033992							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6502	Cc1cccc(C)c1NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N	InChI=1S/C18H16N2O3/c1-11-4-3-5-12(2)17(11)20-18(23)14(10-19)8-13-6-7-15(21)16(22)9-13/h3-9,21-22H,1-2H3,(H,20,23)	FDFVLFGLUAPMGB-UHFFFAOYSA-N	4316	(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2,6-dimethylphenyl)prop-2-enamide::Tyrphostin deriv. 70	Epidermal growth factor receptor	Homo sapiens		 5100							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4316	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4316&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328781	8033993							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6503	Oc1ccc(\C=C(/C#N)C(=O)N2CCCCC2)cc1O	InChI=1S/C15H16N2O3/c16-10-12(15(20)17-6-2-1-3-7-17)8-11-4-5-13(18)14(19)9-11/h4-5,8-9,18-19H,1-3,6-7H2	LNRHMUVQCQDANC-UHFFFAOYSA-N	4421	(2E)-3-(3,4-dihydroxyphenyl)-2-(piperidin-1-ylcarbonyl)prop-2-enenitrile::Tyrphostin deriv. 71	Epidermal growth factor receptor	Homo sapiens		>1000000							Curated from the literature by BindingDB	10.1021/jm00110a022	10.7270/Q2KW5D7V	1676428	aid1795628		Gazit, A; Osherov, N; Posner, I; Yaish, P; Poradosu, E; Gilon, C; Levitzki, A	6/28/1991	5/10/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4421&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328835	8034090							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6504	[#6]-[#8]-c1ccc(\[#6]=[#6](\C#N)C#N)cc1	InChI=1S/C11H4N2O/c1-14-11-4-2-9(3-5-11)6-10(7-12)8-13/h2-5H	CNVXTVIKMWPVSS-UHFFFAOYSA-N	4317	2-[(4-methoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 1	Epidermal growth factor receptor	Homo sapiens	>400000	>1250000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4317	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4317&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2063	8033994							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6505	[#6]-[#8]-c1cc(-[#8]-[#6])cc(\[#6]=[#6](/C#N)C#N)c1	InChI=1S/C12H3N2O2/c1-15-11-4-9(3-10(7-13)8-14)5-12(6-11)16-2/h4-6H	LMVLIAGGAVCODS-UHFFFAOYSA-N	4318	2-[(3,5-dimethoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 2	Epidermal growth factor receptor	Homo sapiens	>400000	>1250000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4318	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4318&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			282723	8033995							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6506	Fc1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C10H4FN2/c11-10-3-1-8(2-4-10)5-9(6-12)7-13/h1-4H	CPLUELYDSNHAAX-UHFFFAOYSA-N	4319	2-[(4-fluorophenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 3	Epidermal growth factor receptor	Homo sapiens	>400000	>1250000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4319	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4319&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			367524	8033996							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6507	[#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(-[#8]-[#6])c1-[#8]	InChI=1S/C12H2N2O3/c1-16-10-4-8(3-9(6-13)7-14)5-11(17-2)12(10)15/h4-5H	PBMAJGSINZIBHB-UHFFFAOYSA-N	4320	2-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 4	Epidermal growth factor receptor	Homo sapiens	 300000	 850000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4320	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4320&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			746495	8033997							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6508	[#8]-[#6](=O)-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C14H4N3O3/c15-8-11(9-16)7-10-1-3-12(4-2-10)17-13(18)5-6-14(19)20/h1-4H	GIYGHVZBXJYFOP-UHFFFAOYSA-N	4321	3-{[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]carbamoyl}propanoic acid::benzylidenemalononitrile (BMN) deriv. 5	Epidermal growth factor receptor	Homo sapiens	 240000	 640000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4321	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4321&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328782	8033998							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6509	N#C\[#6](=[#6]/c1ccc(cc1)-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1)C#N	InChI=1S/C14H4N3O/c15-10-13(11-16)9-12-1-3-14(4-2-12)17-5-7-18-8-6-17/h1-4H	IRHYQHOMLYUTTH-UHFFFAOYSA-N	4322	cid_321779::(4-Morpholinobenzylidene)malononitrile::2-{[4-(morpholin-4-yl)phenyl]methylidene}propanedinitrile::benzylidenemalononitrile (BMN) deriv. 6	Epidermal growth factor receptor	Homo sapiens	>250000	>625000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4322	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4322&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			321779	8033999							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6510	[#8-]-[#7+](=O)-c1cc2-[#8]-[#6]-[#8]-c2cc1\[#6]=[#6](\C#N)C#N	InChI=1S/C11H2N3O4/c12-4-7(5-13)1-8-2-10-11(18-6-17-10)3-9(8)14(15)16/h2-3H	AGROXFHUDBZJHG-UHFFFAOYSA-N	4323	2-[(6-nitro-2H-1,3-benzodioxol-5-yl)methylidene]propanedinitrile::[3,4-(Methylenedioxy)-6-nitrobenzylidene]malononitrile::benzylidenemalononitrile (BMN) deriv. 7	Epidermal growth factor receptor	Homo sapiens		 560000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4323	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4323&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			707914	8034000							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6511	[#8]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C10H4N2O/c11-6-9(7-12)5-8-1-3-10(13)4-2-8/h1-4H	GFUSFFHCWYWLFG-UHFFFAOYSA-N	4324	2-[(4-hydroxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 8	Epidermal growth factor receptor	Homo sapiens	 160000	 560000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4324	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4324&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			92970	8034001							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6512	[#6]C([#6])([#6])c1cc(\[#6]=[#6](/C#N)C#N)cc(c1-[#8])C([#6])([#6])[#6]	InChI=1S/C18H2N2O/c1-17(2,3)14-8-12(7-13(10-19)11-20)9-15(16(14)21)18(4,5)6/h8-9H	BWBIRNQVKDLDJQ-UHFFFAOYSA-N	4325	2-[(3,5-di-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 9	Epidermal growth factor receptor	Homo sapiens	 155000	 460000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4325	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4325&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5614	8034002					C19039		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6513	[#8]-c1cc(\[#6]=[#6](/C#N)C#N)ccc1-[#7+](-[#8-])=O	InChI=1S/C10H3N3O3/c11-5-8(6-12)3-7-1-2-9(13(15)16)10(14)4-7/h1-2,4H	NQDOGMAGGRGJRH-UHFFFAOYSA-N	4326	2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 10	Epidermal growth factor receptor	Homo sapiens	 150000	 450000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4326	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4326&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2046	8034003							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6514	[#8]-[#6](=O)\[#6]=[#6]\c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C13H4N2O2/c14-8-12(9-15)7-11-3-1-10(2-4-11)5-6-13(16)17/h1-4H	RJHNFBULHHCLBB-UHFFFAOYSA-N	4327	(2E)-3-[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 11	Epidermal growth factor receptor	Homo sapiens	 150000	 450000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4327	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4327&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328783	8034004							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6515	[#8]-[#6](=O)-c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C11H4N2O2/c12-6-9(7-13)5-8-1-3-10(4-2-8)11(14)15/h1-4H	QZGYQBCJXMIZHQ-UHFFFAOYSA-N	4328	4-(2,2-dicyanoeth-1-en-1-yl)benzoic acid::benzylidenemalononitrile (BMN) deriv. 12	Epidermal growth factor receptor	Homo sapiens	 143000	 430000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4328	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4328&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328784	8034005							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6516	[#8]-c1cccc(\[#6]=[#6](/C#N)C#N)c1	InChI=1S/C10H4N2O/c11-6-9(7-12)4-8-2-1-3-10(13)5-8/h1-3,5H	VPEXXVQUPIYXRD-UHFFFAOYSA-N	4329	2-[(3-hydroxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 13	Epidermal growth factor receptor	Homo sapiens	 123000	 375000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4329	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4329&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			252473	8034006							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6517	N#C\[#6](=[#6]/c1ccc2-[#8]-[#6]-[#8]-c2c1)C#N	InChI=1S/C11H3N2O2/c12-5-9(6-13)3-8-1-2-10-11(4-8)15-7-14-10/h1-2,4H	WTXKZQOCWXSXEM-UHFFFAOYSA-N	4330	2-(2H-1,3-benzodioxol-5-ylmethylidene)propanedinitrile::benzylidenemalononitrile (BMN) deriv. 14	Epidermal growth factor receptor	Homo sapiens	 117000	 350000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4330	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4330&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			18091	8034007							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6518	[#6]-[#8]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1-[#8]	InChI=1S/C11H3N2O2/c1-15-11-3-2-8(5-10(11)14)4-9(6-12)7-13/h2-3,5H	QUKHPLNHGPOPHO-UHFFFAOYSA-N	4331	2-[(3-hydroxy-4-methoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 15	Epidermal growth factor receptor	Homo sapiens		>250000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4331	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4331&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			694921	8034008							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6519	[#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)ccc1-[#8]	InChI=1S/C11H3N2O2/c1-15-11-5-8(2-3-10(11)14)4-9(6-12)7-13/h2-3,5H	FLOZATMSPHYLBP-UHFFFAOYSA-N	4332	2-[(4-hydroxy-3-methoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 16	Epidermal growth factor receptor	Homo sapiens	 67000	 200000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4332	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4332&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			19424	8034009							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6520	[#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(c1-[#8])-[#7+](-[#8-])=O	InChI=1S/C11H2N3O4/c1-18-10-4-7(2-8(5-12)6-13)3-9(11(10)15)14(16)17/h3-4H	NALSZSUCRSWSIB-UHFFFAOYSA-N	4333	2-[(4-hydroxy-3-methoxy-5-nitrophenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 17	Epidermal growth factor receptor	Homo sapiens	 55000	 160000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4333	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4333&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58857	8034010							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6521	[#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(Br)c1-[#8]	InChI=1S/C11H2BrN2O2/c1-16-10-4-7(2-8(5-13)6-14)3-9(12)11(10)15/h3-4H	NRLFKOFDRKARIG-UHFFFAOYSA-N	4334	2-[(3-bromo-4-hydroxy-5-methoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 18	Epidermal growth factor receptor	Homo sapiens	 50000	 153000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4334	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4334&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57591	8034011							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6522	[#8]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1-[#7+](-[#8-])=O	InChI=1S/C10H3N3O3/c11-5-8(6-12)3-7-1-2-10(14)9(4-7)13(15)16/h1-2,4H	CSWKNTOEZFNOPS-UHFFFAOYSA-N	4335	2-[(4-hydroxy-3-nitrophenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 19	Epidermal growth factor receptor	Homo sapiens	 49000	 125000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4335	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4335&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328785	8034012							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6523	[#8]-c1ccc(c(\[#6]=[#6](/C#N)C#N)c1)-[#7+](-[#8-])=O	InChI=1S/C10H3N3O3/c11-5-7(6-12)3-8-4-9(14)1-2-10(8)13(15)16/h1-2,4H	NIFDXIKYQVKFBD-UHFFFAOYSA-N	4336	2-[(5-hydroxy-2-nitrophenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 20	Epidermal growth factor receptor	Homo sapiens	 24000	 96000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4336	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328786	8034013							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6524	O=[#6]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1	InChI=1S/C11H4N2O/c12-6-11(7-13)5-9-1-3-10(8-14)4-2-9/h1-4H	NPBDQTRGJPQJNS-UHFFFAOYSA-N	4337	2-[(4-formylphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 21	Epidermal growth factor receptor	Homo sapiens	 20000	 60000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4337	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4337&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328787	8034014							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6525	[#8]-c1cc(-[#8])cc(\[#6]=[#6](/C#N)C#N)c1	InChI=1S/C10H3N2O2/c11-5-8(6-12)1-7-2-9(13)4-10(14)3-7/h2-4H	IEJFYFDBMKWLIG-UHFFFAOYSA-N	4338	2-[(3,5-dihydroxyphenyl)methylidene]propanedinitrile::(3,5-Dihydroxybenzylidene)malononitrile::benzylidenemalononitrile (BMN) deriv. 22	Epidermal growth factor receptor	Homo sapiens	 10000	 37000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4338	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4338&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328788	8034015							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6526	[#8]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1-[#8]	InChI=1S/C10H3N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-2,4H	FTIFYYMTIWIJAD-UHFFFAOYSA-N	4339	2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile::(3,4-Dihydroxybenzylidene)malononitrile::cid_2052::benzylidenemalononitrile (BMN) deriv. 23	Epidermal growth factor receptor	Homo sapiens	 11000	 35000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4339	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4339&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2052	8034016							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6527	[#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(-[#8])c1-[#8]	InChI=1S/C11H2N2O3/c1-16-10-4-7(2-8(5-12)6-13)3-9(14)11(10)15/h3-4H	AFRCOCWAUJWBID-UHFFFAOYSA-N	4340	(3,4-Dihydroxy-5-methoxybenzylidene)malononitrile::2-[(3,4-dihydroxy-5-methoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 24	Epidermal growth factor receptor	Homo sapiens	 2200	 6000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4340	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			667645	8034017							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6528	[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(-[#8])c1-[#8]	InChI=1S/C10H2N2O3/c11-4-7(5-12)1-6-2-8(13)10(15)9(14)3-6/h2-3H	RIZNVWODMUYYSK-UHFFFAOYSA-N	4341	2-[(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 25	Epidermal growth factor receptor	Homo sapiens	 1000	 3000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4341	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4341&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2061	8034018							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6529	OC(=O)C(=C\c1ccccc1)\C#N	InChI=1S/C10H7NO2/c11-7-9(10(12)13)6-8-4-2-1-3-5-8/h1-6H,(H,12,13)	CDUQMGQIHYISOP-UHFFFAOYSA-N	4342	(2E)-2-cyano-3-phenylprop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 26	Epidermal growth factor receptor	Homo sapiens	 850000	>2500000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4342	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4342&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			643159	8034019							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6530	COc1ccc(\C=C(/C#N)C(O)=O)cc1	InChI=1S/C11H9NO3/c1-15-10-4-2-8(3-5-10)6-9(7-12)11(13)14/h2-6H,1H3,(H,13,14)	KMHNRJDDHTZZDZ-UHFFFAOYSA-N	4343	(2E)-2-cyano-3-(4-methoxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 27	Epidermal growth factor receptor	Homo sapiens	 833000	 2500000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4343	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4343&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			736236	8034020							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6531	OC(=O)C(=C\c1ccc(F)cc1)\C#N	InChI=1S/C10H6FNO2/c11-9-3-1-7(2-4-9)5-8(6-12)10(13)14/h1-5H,(H,13,14)	OBZAFMILNGLRAL-UHFFFAOYSA-N	4344	(2E)-2-cyano-3-(4-fluorophenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 28	Epidermal growth factor receptor	Homo sapiens	 833000	 2500000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4344&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1550170	8034021							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6532	CN(C)c1ccc(\C=C(/C#N)C(O)=O)cc1	InChI=1S/C12H12N2O2/c1-14(2)11-5-3-9(4-6-11)7-10(8-13)12(15)16/h3-7H,1-2H3,(H,15,16)	CXZXLLVNQYUMAW-UHFFFAOYSA-N	4345	(2E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 29	Epidermal growth factor receptor	Homo sapiens		 1400000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4345&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1550166	8034022							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6533	Cc1ccc(\C=C(/C#N)C(O)=O)cc1	InChI=1S/C11H9NO2/c1-8-2-4-9(5-3-8)6-10(7-12)11(13)14/h2-6H,1H3,(H,13,14)	VSMAAVBAABUVMQ-UHFFFAOYSA-N	4346	(2E)-2-cyano-3-(4-methylphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 30	Epidermal growth factor receptor	Homo sapiens		 1350000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4346	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4346&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1558661	8034023							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6534	OC(=O)C(=C\c1ccc(cc1)[N+]([O-])=O)\C#N	InChI=1S/C10H6N2O4/c11-6-8(10(13)14)5-7-1-3-9(4-2-7)12(15)16/h1-5H,(H,13,14)	WVRIVHWJJWXSTM-UHFFFAOYSA-N	4347	p-Nitro-a-cyanocinnamic Acid::(2E)-2-cyano-3-(4-nitrophenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 31	Epidermal growth factor receptor	Homo sapiens		 1300000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4347&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328789	8034024							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6535	COc1cc(\C=C(/C#N)C(O)=O)ccc1O	InChI=1S/C11H9NO4/c1-16-10-5-7(2-3-9(10)13)4-8(6-12)11(14)15/h2-5,13H,1H3,(H,14,15)	VBHMEVXDNSXEME-UHFFFAOYSA-N	4348	(2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 32	Epidermal growth factor receptor	Homo sapiens	 325000	 800000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4348&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			720879	8034025							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6536	COc1cc(\C=C(/C#N)C(O)=O)cc(OC)c1O	InChI=1S/C12H11NO5/c1-17-9-4-7(3-8(6-13)12(15)16)5-10(18-2)11(9)14/h3-5,14H,1-2H3,(H,15,16)	NDBVLMVMOJCWHU-UHFFFAOYSA-N	4349	(2E)-2-cyano-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 33	Epidermal growth factor receptor	Homo sapiens	 264000	 700000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4349&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328790	8034026							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6537	OC(=O)C(=C\c1ccc(O)cc1)\C#N	InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)	AFVLVVWMAFSXCK-UHFFFAOYSA-N	4350	(2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 34	Epidermal growth factor receptor	Homo sapiens	 165000	 308000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4350&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328791	8034027							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6538	OC(=O)C(=C\c1ccc(C=O)cc1)\C#N	InChI=1S/C11H7NO3/c12-6-10(11(14)15)5-8-1-3-9(7-13)4-2-8/h1-5,7H,(H,14,15)	UJSNKTGYHDLGGE-UHFFFAOYSA-N	4351	(2E)-2-cyano-3-(4-formylphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 35	Epidermal growth factor receptor	Homo sapiens	 47000	 140000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4351	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4351&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328792	8034028							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6539	OC(=O)C(=C\c1ccc(O)c(O)c1)\C#N	InChI=1S/C10H7NO4/c11-5-7(10(14)15)3-6-1-2-8(12)9(13)4-6/h1-4,12-13H,(H,14,15)	CJMWBHLWSMKFSM-UHFFFAOYSA-N	4352	(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 36	Epidermal growth factor receptor	Homo sapiens	 25000	 70000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4352	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4352&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328793	8034029							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6540	[#6]\[#6](=[#6](\C#N)C#N)-c1ccc(-[#7])cc1	InChI=1S/C11H4N3/c1-8(10(6-12)7-13)9-2-4-11(14)5-3-9/h2-5H	IPTVMRNKWOEREA-UHFFFAOYSA-N	4353	2-[1-(4-aminophenyl)ethylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 37	Epidermal growth factor receptor	Homo sapiens		>1250000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4353&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328794	8034030							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6541	COc1cc(ccc1O)C(\C)=C(/C#N)C(O)=O	InChI=1S/C12H11NO4/c1-7(9(6-13)12(15)16)8-3-4-10(14)11(5-8)17-2/h3-5,14H,1-2H3,(H,15,16)	NFHQLTFHKJHSIE-UHFFFAOYSA-N	4354	(2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)but-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 38	Epidermal growth factor receptor	Homo sapiens	 341000	 1100000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4354&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328795	8034031							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6542	NC(=O)C(=C\c1ccc(O)cc1)\C#N	InChI=1S/C10H8N2O2/c11-6-8(10(12)14)5-7-1-3-9(13)4-2-7/h1-5,13H,(H2,12,14)	ILLYSIXRHPOKIQ-UHFFFAOYSA-N	4355	(2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enamide::CHEMBL308048::benzylidenemalononitrile (BMN) deriv. 39	Epidermal growth factor receptor	Homo sapiens		 800000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4355&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328796	8034032		CHEMBL308048					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6543	Oc1ccc(\C=C(/C#N)C(=O)NCC#N)cc1	InChI=1S/C12H9N3O2/c13-5-6-15-12(17)10(8-14)7-9-1-3-11(16)4-2-9/h1-4,7,16H,6H2,(H,15,17)	TWSUNDMWXLUVBD-UHFFFAOYSA-N	4356	(2E)-2-cyano-N-(cyanomethyl)-3-(4-hydroxyphenyl)prop-2-enamide::benzylidenemalononitrile (BMN) deriv. 40	Epidermal growth factor receptor	Homo sapiens	 360000	 625000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4356&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328797	8034033							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6544	[#6]\[#6](=[#6](\C#N)C#N)-c1ccc(-[#7]-[#6](=O)-[#6]-[#6]-[#6](-[#8])=O)cc1	InChI=1S/C15H4N3O3/c1-10(12(8-16)9-17)11-2-4-13(5-3-11)18-14(19)6-7-15(20)21/h2-5H	WWDBVULFZSDIRG-UHFFFAOYSA-N	4357	3-{[4-(1,1-dicyanoprop-1-en-2-yl)phenyl]carbamoyl}propanoic acid::benzylidenemalononitrile (BMN) deriv. 41	Epidermal growth factor receptor	Homo sapiens		 500000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4357	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4357&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328798	8034034							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6545	COc1ccc(cc1)C(=O)C(C#N)C#N	InChI=1S/C11H8N2O2/c1-15-10-4-2-8(3-5-10)11(14)9(6-12)7-13/h2-5,9H,1H3	AXWXLPRMWKUFAW-UHFFFAOYSA-N	4358	2-[hydroxy(4-methoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 42	Epidermal growth factor receptor	Homo sapiens		 450000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4358&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			21853172	8034035							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6546	Oc1ccc(cc1)C(=O)C(C#N)C#N	InChI=1S/C10H6N2O2/c11-5-8(6-12)10(14)7-1-3-9(13)4-2-7/h1-4,8,13H	QVNWVYWUJBWEDI-UHFFFAOYSA-N	4359	2-[hydroxy(4-hydroxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 43	Epidermal growth factor receptor	Homo sapiens		 230000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4359	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4359&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54249210	8034036							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6547	Oc1cc(cc(O)c1O)C(=O)C(C#N)C#N	InChI=1S/C10H6N2O4/c11-3-6(4-12)9(15)5-1-7(13)10(16)8(14)2-5/h1-2,6,13-14,16H	XHBPHEXPTIFHND-UHFFFAOYSA-N	4360	2-[hydroxy(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile::(3,4,5,B-Tetrahydroxybenzylidene)malononitrile::benzylidenemalononitrile (BMN) deriv. 44	Epidermal growth factor receptor	Homo sapiens	 4500	 13500							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4360	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4360&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54469159	8034037							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6548	CC(C)(C)c1cc(\C=C(/C#N)C(N)=O)cc(c1O)C(C)(C)C	InChI=1S/C18H24N2O2/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,21H,1-6H3,(H2,20,22)	GUBROJUTOMZSOC-UHFFFAOYSA-N	4361	(2E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enamide::benzylidenemalononitrile (BMN) deriv. 45	Epidermal growth factor receptor	Homo sapiens		 55000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4361	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4361&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328802	8034038							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6549	c1cc(c(cc1/C=C(\C#N)/C(=O)N)O)O	InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)	USOXQZNJFMKTKJ-UHFFFAOYSA-N	4301	(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide::CHEMBL296407::benzylidenemalononitrile (BMN) deriv. 46::Tyrphostin deriv. 40	Epidermal growth factor receptor	Homo sapiens	 3500	 10000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4301	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4301&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	JGB	6QS5	5328768	8033978		CHEMBL296407					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6550	NC(=S)C(=C\c1ccc(O)c(O)c1)\C#N	InChI=1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)	ZGHQGWOETPXKLY-UHFFFAOYSA-N	4363	alpha-Cyano-(3,4-dihydroxy)thiocinnamide::CHEMBL77030::RG-50864::T7540 (Tyrphostin 47)::Tyrphostin A47::benzylidenemalononitrile (BMN) deriv. 47::(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide::AG 213	Epidermal growth factor receptor	Homo sapiens	 850	 2400							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4363	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4363&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328803	8034039		CHEMBL77030					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6551	Oc1ccc(C=C(C#N)C(=N)C(C#N)C#N)cc1 |w:5.4|	InChI=1S/C13H8N4O/c14-6-10(13(17)11(7-15)8-16)5-9-1-3-12(18)4-2-9/h1-5,11,17-18H	LVERBWQDRRFJMH-UHFFFAOYSA-N	4364	(3Z)-2-amino-3-[(4-hydroxyphenyl)methylidene]prop-1-ene-1,1,3-tricarbonitrile::benzylidenemalononitrile (BMN) deriv. 48	Epidermal growth factor receptor	Homo sapiens		 125							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4364	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4364&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895607	8034040							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6552	Oc1ccc(C=C(C#N)C(=N)C(C#N)C#N)cc1[N+]([O-])=O |w:5.4|	InChI=1S/C13H7N5O3/c14-5-9(13(17)10(6-15)7-16)3-8-1-2-12(19)11(4-8)18(20)21/h1-4,10,17,19H	HIHJOMKUCBPNFS-UHFFFAOYSA-N	4365	(3Z)-2-amino-3-[(4-hydroxy-3-nitrophenyl)methylidene]prop-1-ene-1,1,3-tricarbonitrile::benzylidenemalononitrile (BMN) deriv. 49	Epidermal growth factor receptor	Homo sapiens		 60000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4365	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4365&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895608	8034041							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6553	Oc1ccc(C=C(C#N)C(=N)C(C#N)C#N)cc1O |w:5.4|	InChI=1S/C13H8N4O2/c14-5-9(13(17)10(6-15)7-16)3-8-1-2-11(18)12(19)4-8/h1-4,10,17-19H	AKTXASBDBOSAKZ-UHFFFAOYSA-N	4366	(3Z)-2-amino-3-[(3,4-dihydroxyphenyl)methylidene]prop-1-ene-1,1,3-tricarbonitrile::benzylidenemalononitrile (BMN) deriv. 50	Epidermal growth factor receptor	Homo sapiens		 2500							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4366&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895609	8034042							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6554	Oc1cc(C=C(C#N)C(=N)C(C#N)C#N)cc(O)c1O |w:4.3|	InChI=1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,9,17-20H	OPRGVJUSIWAHDE-UHFFFAOYSA-N	4367	(3Z)-2-amino-3-[(3,4,5-trihydroxyphenyl)methylidene]prop-1-ene-1,1,3-tricarbonitrile::CHEMBL78257::benzylidenemalononitrile (BMN) deriv. 51	Epidermal growth factor receptor	Homo sapiens		 800							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4367&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895610	8034043		CHEMBL78257					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6555	COc1cc(C=C(C#N)C(=N)C(C#N)C#N)cc(O)c1O |w:5.4|	InChI=1S/C14H10N4O3/c1-21-12-4-8(3-11(19)14(12)20)2-9(5-15)13(18)10(6-16)7-17/h2-4,10,18-20H,1H3	PRINOBSDVUFWNK-UHFFFAOYSA-N	4368	(3Z)-2-amino-3-[(3,4-dihydroxy-5-methoxyphenyl)methylidene]prop-1-ene-1,1,3-tricarbonitrile::benzylidenemalononitrile (BMN) deriv. 52	Epidermal growth factor receptor	Homo sapiens		 1200							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4368&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895611	8034044							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6556	Oc1cc(C=C(C#N)C(=N)C(C#N)C#N)cc(Br)c1O |w:4.3|	InChI=1S/C13H7BrN4O2/c14-10-2-7(3-11(19)13(10)20)1-8(4-15)12(18)9(5-16)6-17/h1-3,9,18-20H	GJJNPOJHPLSZEL-UHFFFAOYSA-N	4369	(3Z)-2-amino-3-[(3-bromo-4,5-dihydroxyphenyl)methylidene]prop-1-ene-1,1,3-tricarbonitrile::benzylidenemalononitrile (BMN) deriv. 53	Epidermal growth factor receptor	Homo sapiens		 500							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895612	8034045							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6557	OC(=O)C(=C/c1ccc[nH]1)\C#N	InChI=1S/C8H6N2O2/c9-5-6(8(11)12)4-7-2-1-3-10-7/h1-4,10H,(H,11,12)	RVTZJVIKNDCLAC-UHFFFAOYSA-N	4370	(2Z)-2-cyano-3-(1H-pyrrol-2-yl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 54	Epidermal growth factor receptor	Homo sapiens		 1360000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328810	8034046							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6558	N#CC(=Cc1ccc[nH]1)C#N |(13.27,-4.43,;12.5,-5.77,;11.73,-7.1,;10.27,-7.1,;9.08,-7.98,;7.83,-7.07,;6.59,-7.98,;7.06,-9.44,;8.6,-9.44,;12.5,-8.43,;13.27,-9.77,)|	InChI=1S/C8H5N3/c9-5-7(6-10)4-8-2-1-3-11-8/h1-4,11H	TYUOTJYAWYXOSN-UHFFFAOYSA-N	4371	2-(1H-pyrrol-2-ylmethylidene)propanedinitrile::benzylidenemalononitrile (BMN) deriv. 55	Epidermal growth factor receptor	Homo sapiens		 260000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2795373	8034047							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6559	N#C\[#6](=[#6]/c1ccncc1)C#N	InChI=1S/C9H4N3/c10-6-9(7-11)5-8-1-3-12-4-2-8/h1-4H	WXKAJUGKWHBSEN-UHFFFAOYSA-N	4372	2-(pyridin-4-ylmethylidene)propanedinitrile::benzylidenemalononitrile (BMN) deriv. 56	Epidermal growth factor receptor	Homo sapiens		 250000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390	8034048							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6561	c1cc(ccc1/C=C/C(=O)O)O	InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)	NGSWKAQJJWESNS-UHFFFAOYSA-N	4374	p-Coumaric Acid::p-hydroxycinnamic acid (M4)::CHEMBL66879::(2E)-3-(4-hydroxyphenyl)prop-2-enoic acid::p-hydroxycinnamic acid::p-Hydroxycinnamic acid (p-HCA)::(2E)-3-(4-hydroxyphenyl)prop-2-enoic acid (8)	Epidermal growth factor receptor	Homo sapiens	 1000000	 3000000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	HC4	3PHY,5J0A,2O7B,2O7F,2J3J,1GSX,1GSW,1GSV,4I3J,5MOV,3UME,3UMD,6UN2,3VE4,3VE3,1TS6,1TS7,1TS0,1TS8,1F98,1F9I,2QJ5,2QJ7,1OTD,1OTE,1OTB,8DZX,8DZY,8DZU,5GX9,1T18,1T19,1T1A,1T1B,1T1C,4F8J,1S4R,1S4S,2PYP,6MMD,4EYO,2I9V,3UBA,9AZ9,9AZ7,6UMY,6VZK,5VFM,5Y8T,1XFQ,1XFN,1NWZ,4I3A,2PHY,2KX6,8E1L,4WL9,1OTI,3A5R,3PYP,1S1Z,1S1Y,1OTA,1OT6,1OT9,2D01,4QEM,8BHH,4HY8,1UWN,1D7E,8E03,8E02,8E09,1ODV,1UWP,6MKT,4BBT,4BBU,4BBV,1UGU,4RGR,6TC2,7NR2,8E1K,2D02,7SJJ,2PYR,4WLA,4B9O,2QWS,7NSW,7SPV,7SPW,7SPX,4I38,4I39,4I3I,1MZU,4ALB,2ZOI,2ZOH,5X13	637542	8034050		CHEMBL66879	DB04066		C00811		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6562	c1cc(c(cc1\C=C\C(=O)O)O)O	InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)	QAIPRVGONGVQAS-UHFFFAOYSA-N	4375	3,4-Dihydroxycinnamate, XVII::cid_689043::Caffeic acid, 1::(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid::CHEMBL145::Caffeic acid::(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid (9)::US20240415800, Compound 2-9 (Caffeic Acid)	Epidermal growth factor receptor	Homo sapiens	 400000	 1200000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	DHC	3HOF,2O7D,4FB4,1KOU,6YRI,4YU7,6AWU,4EYQ,5VFJ,6I72,7NRR,7YEN,3S2Z,4N0S	689043	8034051		CHEMBL145	DB01880		C01197		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6563	[#8]-[#6](=O)-[#6](=[#6]/c1ccc(-[#8])cc1)\[#6](-[#8])=O	InChI=1S/C10H4O5/c11-7-3-1-6(2-4-7)5-8(9(12)13)10(14)15/h1-4H	AHZSRNLSLMUMMS-UHFFFAOYSA-N	4376	2-[(4-hydroxyphenyl)methylidene]propanedioic acid::benzylidenemalononitrile (BMN) deriv. 61	Epidermal growth factor receptor	Homo sapiens		 1500000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			519420	8034052							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6564	NC(Cc1ccc(O)c(O)c1)C(O)=O	InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)	WTDRDQBEARUVNC-UHFFFAOYSA-N	4377	2-amino-3-(3,4-dihydroxyphenyl)propanoic acid::L-DOPA::DOPA	Epidermal growth factor receptor	Homo sapiens		 900000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			836	8034053							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6565	Oc1ccc(CC(C#N)C#N)cc1	InChI=1S/C10H8N2O/c11-6-9(7-12)5-8-1-3-10(13)4-2-8/h1-4,9,13H,5H2	PDRLQWJJFLVIRC-UHFFFAOYSA-N	4378	2-[(4-hydroxyphenyl)methyl]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 63	Epidermal growth factor receptor	Homo sapiens		 6500000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4378&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5613	8034054							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6566	Oc1ccc(\C=C\C#N)cc1	InChI=1S/C9H7NO/c10-7-1-2-8-3-5-9(11)6-4-8/h1-6,11H	RZROIDXECXAOTO-UHFFFAOYSA-N	4379	(2E)-3-(4-hydroxyphenyl)prop-2-enenitrile::benzylidenemalononitrile (BMN) deriv. 64	Epidermal growth factor receptor	Homo sapiens		 2400000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328811	8034055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6567	OC(=O)C(=C/c1cc(O)ccc1O)\C#N	InChI=1S/C10H7NO4/c11-5-7(10(14)15)3-6-4-8(12)1-2-9(6)13/h1-4,12-13H,(H,14,15)	OKYSKNYGOHCCIR-UHFFFAOYSA-N	4380	(2Z)-2-cyano-3-(2,5-dihydroxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 65	Epidermal growth factor receptor	Homo sapiens	 24000	 75000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328812	8034056							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6568	COc1ccc(cc1)N=NC(C#N)C#N |w:9.10|	InChI=1S/C10H8N4O/c1-15-10-4-2-8(3-5-10)13-14-9(6-11)7-12/h2-5,9H,1H3	YZCHGZIONBCGFD-UHFFFAOYSA-N	4381	cyano-N-(4-methoxyphenyl)methanecarbohydrazonoyl cyanide::[(p-Methoxyphenyl)hydrazono]malononitrile::benzylidenemalononitrile (BMN) deriv. 67	Epidermal growth factor receptor	Homo sapiens		 600000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			228618	8034057							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6569	Oc1ccc(cc1)N=NC(C#N)C#N |w:8.9|	InChI=1S/C9H6N4O/c10-5-8(6-11)13-12-7-1-3-9(14)4-2-7/h1-4,8,14H	SITMWOVIGUQVHK-UHFFFAOYSA-N	4382	cyano-N-(4-hydroxyphenyl)methanecarbohydrazonoyl cyanide::benzylidenemalononitrile (BMN) deriv. 68	Epidermal growth factor receptor	Homo sapiens		 225000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4382&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			75465287	8034058							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6570	Oc1ccc(cc1)N=CC(C#N)C#N |w:8.9|	InChI=1S/C10H7N3O/c11-5-8(6-12)7-13-9-1-3-10(14)4-2-9/h1-4,7-8,14H	PWSIIVCKYNJKKF-UHFFFAOYSA-N	4383	[(p-Hydroxyanilino)methylene]malononitrile::2-{[(4-hydroxyphenyl)amino]methylidene}propanedinitrile::benzylidenemalononitrile (BMN) deriv. 69	Epidermal growth factor receptor	Homo sapiens		 350000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54212223	8034059							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6571	O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6](/C#N)C#N)-[#6](=O)-[#7]-1	InChI=1S/C7N4O3/c8-1-3(2-9)4-5(12)10-7(14)11-6(4)13	VWYVQCARAVXOEZ-UHFFFAOYSA-N	4384	2-(2,4,6-trioxo-1,3-diazinan-5-ylidene)propanedinitrile::benzylidenemalononitrile (BMN) deriv. 70	Epidermal growth factor receptor	Homo sapiens		 1400000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328815	8034060							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6572	Oc1ccc(O)c(\C=C\NC=O)c1	InChI=1S/C9H9NO3/c11-6-10-4-3-7-5-8(12)1-2-9(7)13/h1-6,12-13H,(H,10,11)	SIHZWGODIRRSRA-UHFFFAOYSA-N	3973	N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide::cid_58035::erbstatin	Epidermal growth factor receptor	Homo sapiens		 14000							Curated from the literature by BindingDB	10.1021/jm00130a020	10.7270/Q2G44NHF	2552117	aid1795632		Gazit, A; Yaish, P; Gilon, C; Levitzki, A	10/28/1989	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3973	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3973&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328552	8033670					C06049		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6573	Cc1cccc2c(Nc3cccc(Cl)c3)ncnc12	InChI=1S/C15H12ClN3/c1-10-4-2-7-13-14(10)17-9-18-15(13)19-12-6-3-5-11(16)8-12/h2-9H,1H3,(H,17,18,19)	MTWNTLCPFTVRPR-UHFFFAOYSA-N	4386	N-(3-chlorophenyl)-8-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 1a	Epidermal growth factor receptor	Homo sapiens		>100000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328816	8034061							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6574	Clc1cccc(Nc2ncnc3ccccc23)c1	InChI=1S/C14H10ClN3/c15-10-4-3-5-11(8-10)18-14-12-6-1-2-7-13(12)16-9-17-14/h1-9H,(H,16,17,18)	ZKKVUIPXPPDIRD-UHFFFAOYSA-N	3263	CHEMBL329672::N-(3-chlorophenyl)quinazolin-4-amine::CHEMBL555321::4-Anilino quinazoline deriv. 14	Epidermal growth factor receptor	Homo sapiens		 4160					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3263	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3263&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			128872	8033005		CHEMBL555321CHEMBL329672					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6575	Clc1ccccc1Nc1ncnc2ccccc12	InChI=1S/C14H10ClN3/c15-11-6-2-4-8-13(11)18-14-10-5-1-3-7-12(10)16-9-17-14/h1-9H,(H,16,17,18)	JFEPDHKPKRYMNW-UHFFFAOYSA-N	4388	N-(2-chlorophenyl)quinazolin-4-amine::4-Anilidoquinazoline deriv. 3b	Epidermal growth factor receptor	Homo sapiens		 15300					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4388	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4388&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			712154	8034062							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6576	COc1cc2ncnc(Nc3ccccc3)c2cc1OC	InChI=1S/C16H15N3O2/c1-20-14-8-12-13(9-15(14)21-2)17-10-18-16(12)19-11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,19)	MJKCGAHOCZLYDG-UHFFFAOYSA-N	3530	6,7-dimethoxy-N-phenylquinazolin-4-amine::CHEMBL542484::CHEMBL94191::PD153035 Analog 29	Epidermal growth factor receptor	Homo sapiens		 5100					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3530&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3798	8033255		CHEMBL94191CHEMBL542484					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6577	COc1cc2ncnc(Nc3cccc(F)c3)c2cc1OC	InChI=1S/C16H14FN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	DFWBDVRBHHFDNZ-UHFFFAOYSA-N	3531	CHEMBL541586::N-(3-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL94431::PD153035 Analog 30	Epidermal growth factor receptor	Homo sapiens		 90					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1474883	8033256		CHEMBL94431CHEMBL541586					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6578	COc1cc2c(cc1OC)ncnc2Nc3cccc(c3)Cl	InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	GFNNBHLJANVSQV-UHFFFAOYSA-N	3532	CHEMBL7917::CHEMBL540068::N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035 Analog 31	Epidermal growth factor receptor	Homo sapiens		 900					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3532&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0TO	4FEX	2051	8033257		CHEMBL540068CHEMBL7917					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6579	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	LSPANGZZENHZNJ-UHFFFAOYSA-N	3032	CHEMBL29197::N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL1204168::PD153035::US9422297, PD153035::US11111252, Compound PD153035::US11001595, Compound PD153035	Epidermal growth factor receptor	Homo sapiens		 16					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3032&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4705	8032779		CHEMBL1204168CHEMBL29197					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6580	COc1cc2ncnc(Nc3cccc(I)c3)c2cc1OC	InChI=1S/C16H14IN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	FGCLAQLIXMAIHT-UHFFFAOYSA-N	3533	CHEMBL1204305::N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL96065::PD153035 Analog 33	Epidermal growth factor receptor	Homo sapiens		 950					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328201	8033258		CHEMBL96065CHEMBL1204305					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6581	COc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1	InChI=1S/C17H17N3O3/c1-21-12-6-4-5-11(7-12)20-17-13-8-15(22-2)16(23-3)9-14(13)18-10-19-17/h4-10H,1-3H3,(H,18,19,20)	FMZCWRYXPHDICO-UHFFFAOYSA-N	4394	6,7-dimethoxy-N-(3-methoxyphenyl)quinazolin-4-amine::Methoxy Aniline 1::4-Anilidoquinazoline deriv. 9a	Epidermal growth factor receptor	Homo sapiens		 6300					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4394	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4394&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2808988	8034063							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6582	COc1cc2ncnc(Nc3cc(Cl)cc(Cl)c3)c2cc1OC	InChI=1S/C16H13Cl2N3O2/c1-22-14-6-12-13(7-15(14)23-2)19-8-20-16(12)21-11-4-9(17)3-10(18)5-11/h3-8H,1-2H3,(H,19,20,21)	ODARZGIYUZVYJH-UHFFFAOYSA-N	4395	N-(3,5-dichlorophenyl)-6,7-dimethoxyquinazolin-4-amine::4-Anilidoquinazoline deriv. 10a	Epidermal growth factor receptor	Homo sapiens		 4000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4395&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328817	8034064							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6583	COc1cc2c(Nc3cccc(Cl)c3)ncnc2c(OC)c1OC	InChI=1S/C17H16ClN3O3/c1-22-13-8-12-14(16(24-3)15(13)23-2)19-9-20-17(12)21-11-6-4-5-10(18)7-11/h4-9H,1-3H3,(H,19,20,21)	KXYHTLLUNBBBQS-UHFFFAOYSA-N	4396	N-(3-chlorophenyl)-6,7,8-trimethoxyquinazolin-4-amine::4-Anilidoquinazoline deriv. 11b	Epidermal growth factor receptor	Homo sapiens		>100000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4396&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328818	8034065							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6584	Clc1cccc(Nc2ncnc3ccc(Cl)cc23)c1	InChI=1S/C14H9Cl2N3/c15-9-2-1-3-11(6-9)19-14-12-7-10(16)4-5-13(12)17-8-18-14/h1-8H,(H,17,18,19)	QKCFZLIUAVWYRM-UHFFFAOYSA-N	4397	6-chloro-N-(3-chlorophenyl)quinazolin-4-amine::4-Anilidoquinazoline deriv. 12a	Epidermal growth factor receptor	Homo sapiens		 2700					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4397&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328819	8034066							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6585	Cc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1	InChI=1S/C15H12ClN3/c1-10-5-6-14-13(7-10)15(18-9-17-14)19-12-4-2-3-11(16)8-12/h2-9H,1H3,(H,17,18,19)	LAIPDDVIUXSDNH-UHFFFAOYSA-N	4398	N-(3-chlorophenyl)-6-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 13a	Epidermal growth factor receptor	Homo sapiens		 600					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4398&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			720613	8034067							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6586	Cc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C15H12BrN3/c1-10-5-6-14-13(7-10)15(18-9-17-14)19-12-4-2-3-11(16)8-12/h2-9H,1H3,(H,17,18,19)	DBGKBBBQSQCERH-UHFFFAOYSA-N	4399	N-(3-bromophenyl)-6-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 14a	Epidermal growth factor receptor	Homo sapiens		 1700					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4399	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4399&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328820	8034068							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6587	Cc1ccc2ncnc(Nc3cccc(c3)C(F)(F)F)c2c1	InChI=1S/C16H12F3N3/c1-10-5-6-14-13(7-10)15(21-9-20-14)22-12-4-2-3-11(8-12)16(17,18)19/h2-9H,1H3,(H,20,21,22)	NFEUTOJRUZZNQS-UHFFFAOYSA-N	4400	6-methyl-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine::4-Anilidoquinazoline deriv. 15b	Epidermal growth factor receptor	Homo sapiens		 2100					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4400&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			721010	8034069							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6588	Cc1ccc2ncnc(Nc3ccc(I)cc3)c2c1	InChI=1S/C15H12IN3/c1-10-2-7-14-13(8-10)15(18-9-17-14)19-12-5-3-11(16)4-6-12/h2-9H,1H3,(H,17,18,19)	FOCXBYSXUCIARP-UHFFFAOYSA-N	4401	N-(4-iodophenyl)-6-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 17a	Epidermal growth factor receptor	Homo sapiens		>50000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1185409	8034070							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6589	Cc1ccc2ncnc(Nc3ccc(cc3)C#N)c2c1	InChI=1S/C16H12N4/c1-11-2-7-15-14(8-11)16(19-10-18-15)20-13-5-3-12(9-17)4-6-13/h2-8,10H,1H3,(H,18,19,20)	AXXCJNPBASXGLQ-UHFFFAOYSA-N	4402	4-[(6-methylquinazolin-4-yl)amino]benzonitrile::4-Anilidoquinazoline deriv. 18a	Epidermal growth factor receptor	Homo sapiens		 22000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328821	8034071							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6590	Cc1ccc2ncnc(Nc3cccc(c3)C(N)=O)c2c1	InChI=1S/C16H14N4O/c1-10-5-6-14-13(7-10)16(19-9-18-14)20-12-4-2-3-11(8-12)15(17)21/h2-9H,1H3,(H2,17,21)(H,18,19,20)	MICFRXNRMMKOHU-UHFFFAOYSA-N	4403	3-[(6-methylquinazolin-4-yl)amino]benzamide::4-Anilidoquinazoline deriv. 19a	Epidermal growth factor receptor	Homo sapiens		 250							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328822	8034072							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6591	Cc1ccc2ncnc(Nc3cccc(c3)C(O)=O)c2c1	InChI=1S/C16H13N3O2/c1-10-5-6-14-13(7-10)15(18-9-17-14)19-12-4-2-3-11(8-12)16(20)21/h2-9H,1H3,(H,20,21)(H,17,18,19)	GCEMMLDIYZUPDK-UHFFFAOYSA-N	4404	3-[(6-methylquinazolin-4-yl)amino]benzoic acid::4-Anilidoquinazoline deriv. 20a	Epidermal growth factor receptor	Homo sapiens		 1000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			735129	8034073							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6592	Cc1ccc2ncnc(Nc3ccc(C)c(C)c3)c2c1	InChI=1S/C17H17N3/c1-11-4-7-16-15(8-11)17(19-10-18-16)20-14-6-5-12(2)13(3)9-14/h4-10H,1-3H3,(H,18,19,20)	RPNYYQCXJXDGDW-UHFFFAOYSA-N	4405	N-(3,4-dimethylphenyl)-6-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 21a	Epidermal growth factor receptor	Homo sapiens		 6900							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			720610	8034074							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6593	Cc1ccc2ncnc(Nc3ccc4OCOc4c3)c2c1	InChI=1S/C16H13N3O2/c1-10-2-4-13-12(6-10)16(18-8-17-13)19-11-3-5-14-15(7-11)21-9-20-14/h2-8H,9H2,1H3,(H,17,18,19)	CZJCSUFPUYPACT-UHFFFAOYSA-N	4406	N-(2H-1,3-benzodioxol-5-yl)-6-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 22b	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4406	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4406&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328823	8034075							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6594	Cc1ccc2ncnc(Nc3ccccc3C)c2c1	InChI=1S/C16H15N3/c1-11-7-8-15-13(9-11)16(18-10-17-15)19-14-6-4-3-5-12(14)2/h3-10H,1-2H3,(H,17,18,19)	MTZMNJDZBLFIAM-UHFFFAOYSA-N	4407	6-methyl-N-(2-methylphenyl)quinazolin-4-amine::4-Anilidoquinazoline deriv. 23a	Epidermal growth factor receptor	Homo sapiens		 21000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328824	8034076							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6595	Cc1ccc2ncnc(Nc3ccc(O)cc3)c2c1	InChI=1S/C15H13N3O/c1-10-2-7-14-13(8-10)15(17-9-16-14)18-11-3-5-12(19)6-4-11/h2-9,19H,1H3,(H,16,17,18)	ZFVYHWPXSXICAQ-UHFFFAOYSA-N	4408	4-[(6-methylquinazolin-4-yl)amino]phenol::4-Anilidoquinazoline deriv. 24a	Epidermal growth factor receptor	Homo sapiens		 15000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328825	8034077							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6596	Cc1ccc2ncnc(Nc3ccccc3Cl)c2c1	InChI=1S/C15H12ClN3/c1-10-6-7-13-11(8-10)15(18-9-17-13)19-14-5-3-2-4-12(14)16/h2-9H,1H3,(H,17,18,19)	AJVNFXAVAVZEJI-UHFFFAOYSA-N	4409	N-(2-chlorophenyl)-6-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 25b	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			721003	8034078							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6597	Cc1ccc2ncnc(Nc3ccc(cc3)C(O)=O)c2c1	InChI=1S/C16H13N3O2/c1-10-2-7-14-13(8-10)15(18-9-17-14)19-12-5-3-11(4-6-12)16(20)21/h2-9H,1H3,(H,20,21)(H,17,18,19)	JQLHKPXFVRGGFZ-UHFFFAOYSA-N	4410	4-[(6-methylquinazolin-4-yl)amino]benzoic acid::4-Anilidoquinazoline deriv. 26a	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4410	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4410&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328826	8034079							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6598	COc1ccc(Nc2ncnc3ccc(C)cc23)cc1	InChI=1S/C16H15N3O/c1-11-3-8-15-14(9-11)16(18-10-17-15)19-12-4-6-13(20-2)7-5-12/h3-10H,1-2H3,(H,17,18,19)	DGKCFCAEKHZWMW-UHFFFAOYSA-N	4411	cid_721008::N-(4-methoxyphenyl)-6-methylquinazolin-4-amine::4-Anilidoquinazoline deriv. 27a	Epidermal growth factor receptor	Homo sapiens		 9000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4411	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			721008	8034080							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6599	Cc1ccc(Nc2ncnc3ccc(C)cc23)cc1	InChI=1S/C16H15N3/c1-11-3-6-13(7-4-11)19-16-14-9-12(2)5-8-15(14)17-10-18-16/h3-10H,1-2H3,(H,17,18,19)	ZDJCXAZTDGVCCQ-UHFFFAOYSA-N	4412	6-methyl-N-(4-methylphenyl)quinazolin-4-amine::4-Anilidoquinazoline deriv. 28b	Epidermal growth factor receptor	Homo sapiens		 10000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4412	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4412&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328827	8034081							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6600	Cc1ccc2ncnc(Nc3ccccc3)c2c1	InChI=1S/C15H13N3/c1-11-7-8-14-13(9-11)15(17-10-16-14)18-12-5-3-2-4-6-12/h2-10H,1H3,(H,16,17,18)	JFDWMFYUKLPRSP-UHFFFAOYSA-N	4413	6-methyl-N-phenylquinazolin-4-amine::4-Anilidoquinazoline deriv. 29b	Epidermal growth factor receptor	Homo sapiens		 11300							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4413	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4413&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			720609	8034082							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6601	Cc1ccc2ncnc(Nc3ccccc3O)c2c1	InChI=1S/C15H13N3O/c1-10-6-7-12-11(8-10)15(17-9-16-12)18-13-4-2-3-5-14(13)19/h2-9,19H,1H3,(H,16,17,18)	JQEXCZFMOALLKY-UHFFFAOYSA-N	4414	2-[(6-methylquinazolin-4-yl)amino]phenol::4-Anilidoquinazoline deriv. 30b	Epidermal growth factor receptor	Homo sapiens		 13000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4414	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4414&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328828	8034083							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6602	COc1cc2nc(Cl)nc(Nc3ccc(C)cc3)c2cc1OC	InChI=1S/C17H16ClN3O2/c1-10-4-6-11(7-5-10)19-16-12-8-14(22-2)15(23-3)9-13(12)20-17(18)21-16/h4-9H,1-3H3,(H,19,20,21)	VBFXQIVTEKYBPS-UHFFFAOYSA-N	4415	2-chloro-6,7-dimethoxy-N-(4-methylphenyl)quinazolin-4-amine::4-Anilidoquinazoline deriv. 31b	Epidermal growth factor receptor	Homo sapiens		 16000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4415	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4415&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328829	8034084							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6603	COc1cc2nc(Nc3ccc(C)cc3)nc(Nc3ccc(C)cc3)c2cc1OC	InChI=1S/C24H24N4O2/c1-15-5-9-17(10-6-15)25-23-19-13-21(29-3)22(30-4)14-20(19)27-24(28-23)26-18-11-7-16(2)8-12-18/h5-14H,1-4H3,(H2,25,26,27,28)	CIHXAAJUXLYSLJ-UHFFFAOYSA-N	4416	6,7-dimethoxy-2-N,4-N-bis(4-methylphenyl)quinazoline-2,4-diamine::4-Anilidoquinazoline deriv. 32b	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328830	8034085							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6604	COc1cc2nc(nc(Nc3cccc(Cl)c3)c2cc1OC)N1CCN(C)CC1	InChI=1S/C21H24ClN5O2/c1-26-7-9-27(10-8-26)21-24-17-13-19(29-3)18(28-2)12-16(17)20(25-21)23-15-6-4-5-14(22)11-15/h4-6,11-13H,7-10H2,1-3H3,(H,23,24,25)	APICIERXNBVOHG-UHFFFAOYSA-N	4417	N-(3-chlorophenyl)-6,7-dimethoxy-2-(4-methylpiperazin-1-yl)quinazolin-4-amine::4-Anilidoquinazoline deriv. 33b	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328831	8034086							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6605	COc1cc2nc(Nc3cccc(Cl)c3)nc(Nc3cccc(Cl)c3)c2cc1OC	InChI=1S/C22H18Cl2N4O2/c1-29-19-11-17-18(12-20(19)30-2)27-22(26-16-8-4-6-14(24)10-16)28-21(17)25-15-7-3-5-13(23)9-15/h3-12H,1-2H3,(H2,25,26,27,28)	GSIJXOGHJUOJKI-UHFFFAOYSA-N	4418	2-N,4-N-bis(3-chlorophenyl)-6,7-dimethoxyquinazoline-2,4-diamine::4-Anilidoquinazoline deriv. 34b	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328832	8034087							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6606	COc1cc2nc(nc(Nc3cccc(Cl)c3)c2cc1OC)N1CCN(CC1)c1ccccc1	InChI=1S/C26H26ClN5O2/c1-33-23-16-21-22(17-24(23)34-2)29-26(30-25(21)28-19-8-6-7-18(27)15-19)32-13-11-31(12-14-32)20-9-4-3-5-10-20/h3-10,15-17H,11-14H2,1-2H3,(H,28,29,30)	ISUCGPXEDXWPBD-UHFFFAOYSA-N	4419	N-(3-chlorophenyl)-6,7-dimethoxy-2-(4-phenylpiperazin-1-yl)quinazolin-4-amine::4-Anilidoquinazoline deriv. 35b	Epidermal growth factor receptor	Homo sapiens		>50000							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328833	8034088							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6607	COc1cc2nc(Cl)nc(Nc3cccc(Cl)c3)c2cc1OC	InChI=1S/C16H13Cl2N3O2/c1-22-13-7-11-12(8-14(13)23-2)20-16(18)21-15(11)19-10-5-3-4-9(17)6-10/h3-8H,1-2H3,(H,19,20,21)	URYKHFOATQIJDL-UHFFFAOYSA-N	4420	2-chloro-N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine::4-Anilidoquinazoline deriv. 36b	Epidermal growth factor receptor	Homo sapiens		 2800							Curated from the literature by BindingDB	10.1016/0968-0896(96)00107-1	10.7270/Q2BC3WR8	8879541	aid1795635		Gazit, A; Chen, J; App, H; McMahon, G; Hirth, P; Chen, I; Levitzki, A	8/28/1996	5/9/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4420	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4420&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328834	8034089							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6628	CCOC(=O)c1cnc2cc(OC)c(OC)cc2c1Nc1cccc(Br)c1	InChI=1S/C20H19BrN2O4/c1-4-27-20(24)15-11-22-16-10-18(26-3)17(25-2)9-14(16)19(15)23-13-7-5-6-12(21)8-13/h5-11H,4H2,1-3H3,(H,22,23)	JTCMPRGLTUXNFT-UHFFFAOYSA-N	4442	ethyl 4-[(3-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carboxylate::4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carboxylic Acid Ethyl Ester::4-Anilino-6,7-dialkoxyquinoline deriv. 5	Epidermal growth factor receptor	Homo sapiens		 81300					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4442&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328837	8034111							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6629	CCOc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OCC	InChI=1S/C20H18BrN3O2/c1-3-25-18-9-16-17(10-19(18)26-4-2)23-12-13(11-22)20(16)24-15-7-5-6-14(21)8-15/h5-10,12H,3-4H2,1-2H3,(H,23,24)	ZXILYRWRAKLTOG-UHFFFAOYSA-N	4443	4-[(3-bromophenyl)amino]-6,7-diethoxyquinoline-3-carbonitrile::4-(3-Bromophenylamino)-6,7-diethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 6	Epidermal growth factor receptor	Homo sapiens		 420					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328838	8034112							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6630	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1OCC	InChI=1S/C20H17ClFN3O2/c1-3-26-18-8-14-17(9-19(18)27-4-2)24-11-12(10-23)20(14)25-13-5-6-16(22)15(21)7-13/h5-9,11H,3-4H2,1-2H3,(H,24,25)	VJTVBWNBERHDKM-UHFFFAOYSA-N	4444	4-[(3-chloro-4-fluorophenyl)amino]-6,7-diethoxyquinoline-3-carbonitrile::4-(3-Chloro-4-fluorophenylamino)-6,7-diethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 7	Epidermal growth factor receptor	Homo sapiens		 980					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328839	8034113							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6631	COc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C18H14BrN3O2/c1-23-16-7-14-15(8-17(16)24-2)21-10-11(9-20)18(14)22-13-5-3-4-12(19)6-13/h3-8,10H,1-2H3,(H,21,22)	CQKFTSMPIIYOBX-UHFFFAOYSA-N	4445	4-[(3-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::CHEMBL111038::4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 8	Epidermal growth factor receptor	Homo sapiens		 190					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328840	8034114		CHEMBL111038					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6632	COc1cc2ncc(C#N)c(Nc3cccc(Cl)c3)c2cc1OC	InChI=1S/C18H14ClN3O2/c1-23-16-7-14-15(8-17(16)24-2)21-10-11(9-20)18(14)22-13-5-3-4-12(19)6-13/h3-8,10H,1-2H3,(H,21,22)	HLBGGOYPNRIHFH-UHFFFAOYSA-N	4446	4-[(3-chlorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(3-Chlorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 9	Epidermal growth factor receptor	Homo sapiens		 180					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328841	8034115							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6633	COc1cc2ncc(C#N)c(Nc3cccc(c3)C(F)(F)F)c2cc1OC	InChI=1S/C19H14F3N3O2/c1-26-16-7-14-15(8-17(16)27-2)24-10-11(9-23)18(14)25-13-5-3-4-12(6-13)19(20,21)22/h3-8,10H,1-2H3,(H,24,25)	NPVUUFCFLLPVCM-UHFFFAOYSA-N	4447	6,7-Dimethoxy-4-(3-trifluoromethylphenylamino)-quinoline-3-carbonitrile::6,7-dimethoxy-4-{[3-(trifluoromethyl)phenyl]amino}quinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 10	Epidermal growth factor receptor	Homo sapiens		 1450					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328842	8034116							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6634	COc1ccc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)cc1OC	InChI=1S/C20H19N3O4/c1-24-16-6-5-13(7-17(16)25-2)23-20-12(10-21)11-22-15-9-19(27-4)18(26-3)8-14(15)20/h5-9,11H,1-4H3,(H,22,23)	PPNMPEHEXLGGID-UHFFFAOYSA-N	4448	4-Anilino-3-cyanoquinoline deriv. 7e::4-[(3,4-dimethoxyphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(3,4-Dimethoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 11	Epidermal growth factor receptor	Homo sapiens		 50490					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328843	8034117							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6635	COc1cc2ncc(C#N)c(Nc3cccc(F)c3)c2cc1OC	InChI=1S/C18H14FN3O2/c1-23-16-7-14-15(8-17(16)24-2)21-10-11(9-20)18(14)22-13-5-3-4-12(19)6-13/h3-8,10H,1-2H3,(H,21,22)	OLNMDVMEJYNZBA-UHFFFAOYSA-N	4449	4-[(3-fluorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(3-Fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 12	Epidermal growth factor receptor	Homo sapiens		 740					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328844	8034118							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6636	COc1cc2ncc(C#N)c(Nc3cccc(c3)C#N)c2cc1OC	InChI=1S/C19H14N4O2/c1-24-17-7-15-16(8-18(17)25-2)22-11-13(10-21)19(15)23-14-5-3-4-12(6-14)9-20/h3-8,11H,1-2H3,(H,22,23)	CCECSDRSBLPTHW-UHFFFAOYSA-N	4450	4-(3-Cyanophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(3-cyanophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 13	Epidermal growth factor receptor	Homo sapiens		 14180					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4450&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328845	8034119							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6637	COc1cc2ncc(C#N)c(Nc3ccc(F)cc3)c2cc1OC	InChI=1S/C18H14FN3O2/c1-23-16-7-14-15(8-17(16)24-2)21-10-11(9-20)18(14)22-13-5-3-12(19)4-6-13/h3-8,10H,1-2H3,(H,21,22)	PICBGXSASXFIAL-UHFFFAOYSA-N	4451	4-(4-Fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(4-fluorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 14	Epidermal growth factor receptor	Homo sapiens		 47940					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4451&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328846	8034120							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6638	COc1cc2ncc(C#N)c(Nc3cccc(c3)C(C)=O)c2cc1OC	InChI=1S/C20H17N3O3/c1-12(24)13-5-4-6-15(7-13)23-20-14(10-21)11-22-17-9-19(26-3)18(25-2)8-16(17)20/h4-9,11H,1-3H3,(H,22,23)	IGMHTUVNOCQQMP-UHFFFAOYSA-N	4452	4-(3-Acetylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(3-acetylphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 15	Epidermal growth factor receptor	Homo sapiens		 7380					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4452&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328847	8034121							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6639	COc1cc2ncc(C#N)c(Nc3cccc(N)c3)c2cc1OC	InChI=1S/C18H16N4O2/c1-23-16-7-14-15(8-17(16)24-2)21-10-11(9-19)18(14)22-13-5-3-4-12(20)6-13/h3-8,10H,20H2,1-2H3,(H,21,22)	MZQKSJFIOAVZJR-UHFFFAOYSA-N	4453	4-(3-Aminophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(3-aminophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 16	Epidermal growth factor receptor	Homo sapiens		 820					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4453&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328848	8034122							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6640	COc1cc2ncc(C#N)c(Nc3cccc(c3)N(C)C)c2cc1OC	InChI=1S/C20H20N4O2/c1-24(2)15-7-5-6-14(8-15)23-20-13(11-21)12-22-17-10-19(26-4)18(25-3)9-16(17)20/h5-10,12H,1-4H3,(H,22,23)	OLPCFXOXZCAXNQ-UHFFFAOYSA-N	4454	4-{[3-(dimethylamino)phenyl]amino}-6,7-dimethoxyquinoline-3-carbonitrile::4-(3-Dimethylaminophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 17	Epidermal growth factor receptor	Homo sapiens		 850					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4454&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328849	8034123							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6641	COc1cc2ncc(C#N)c(Nc3cccc(c3)[N+]([O-])=O)c2cc1OC	InChI=1S/C18H14N4O4/c1-25-16-7-14-15(8-17(16)26-2)20-10-11(9-19)18(14)21-12-4-3-5-13(6-12)22(23)24/h3-8,10H,1-2H3,(H,20,21)	WEOXCMIQDJTOOP-UHFFFAOYSA-N	4455	6,7-dimethoxy-4-[(3-nitrophenyl)amino]quinoline-3-carbonitrile::4-(3-Nitrophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 18	Epidermal growth factor receptor	Homo sapiens		 870					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4455&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328850	8034124							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6642	COc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1OC	InChI=1S/C18H13ClFN3O2/c1-24-16-6-12-15(7-17(16)25-2)22-9-10(8-21)18(12)23-11-3-4-14(20)13(19)5-11/h3-7,9H,1-2H3,(H,22,23)	LNWSYCUKHBLOIW-UHFFFAOYSA-N	4456	4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(3-chloro-4-fluorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::CHEMBL109372::6,7-dialkoxyquinoline-3-carbonitrile deriv. 19	Epidermal growth factor receptor	Homo sapiens		 540					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4456&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328851	8034125		CHEMBL109372					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6643	COc1cc2ncc(C#N)c(Nc3ccc(Cl)cc3F)c2cc1OC	InChI=1S/C18H13ClFN3O2/c1-24-16-6-12-15(7-17(16)25-2)22-9-10(8-21)18(12)23-14-4-3-11(19)5-13(14)20/h3-7,9H,1-2H3,(H,22,23)	AZGVCABJHURYHG-UHFFFAOYSA-N	4457	4-Phenylamino-3-quinolinecarbonitrile deriv. 2r::4-[(4-chloro-2-fluorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(4-Chloro-2-fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 20	Epidermal growth factor receptor	Homo sapiens		 13850					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4457&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328852	8034126							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6644	COc1cc2ncc(C#N)c(Nc3cccc(O)c3)c2cc1OC	InChI=1S/C18H15N3O3/c1-23-16-7-14-15(8-17(16)24-2)20-10-11(9-19)18(14)21-12-4-3-5-13(22)6-12/h3-8,10,22H,1-2H3,(H,20,21)	IKUBPVIBISSEJV-UHFFFAOYSA-N	4458	4-[(3-hydroxyphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(3-Hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 21	Epidermal growth factor receptor	Homo sapiens		 6360					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4458&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328853	8034127							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6645	COc1cc2ncc(C#N)c(Nc3ccc(C)cc3)c2cc1OC	InChI=1S/C19H17N3O2/c1-12-4-6-14(7-5-12)22-19-13(10-20)11-21-16-9-18(24-3)17(23-2)8-15(16)19/h4-9,11H,1-3H3,(H,21,22)	JXLUYPNXIHHINO-UHFFFAOYSA-N	4459	6,7-dimethoxy-4-[(4-methylphenyl)amino]quinoline-3-carbonitrile::4-(4-Methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 22	Epidermal growth factor receptor	Homo sapiens		 2730							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4459&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328854	8034128							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6646	COc1cc2ncc(C#N)c(Nc3cccc(c3)C(N)=O)c2cc1OC	InChI=1S/C19H16N4O3/c1-25-16-7-14-15(8-17(16)26-2)22-10-12(9-20)18(14)23-13-5-3-4-11(6-13)19(21)24/h3-8,10H,1-2H3,(H2,21,24)(H,22,23)	SFJYOSIAYPFZDP-UHFFFAOYSA-N	4460	3-(3-Cyano-6,7-dimethoxyquinolin-4-ylamino)benzamide::3-[(3-cyano-6,7-dimethoxyquinolin-4-yl)amino]benzamide::6,7-dialkoxyquinoline-3-carbonitrile deriv. 23	Epidermal growth factor receptor	Homo sapiens		 7690							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4460&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328855	8034129							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6647	COc1cc2ncc(C#N)c(Nc3ccc(C)c(Br)c3)c2cc1OC	InChI=1S/C19H16BrN3O2/c1-11-4-5-13(6-15(11)20)23-19-12(9-21)10-22-16-8-18(25-3)17(24-2)7-14(16)19/h4-8,10H,1-3H3,(H,22,23)	BOXDQGATHFGEIB-UHFFFAOYSA-N	4461	4-[(3-bromo-4-methylphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(3-Bromo-4-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 24	Epidermal growth factor receptor	Homo sapiens		 1790							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4461&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328856	8034130							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6648	COc1cc2ncc(C#N)c(Nc3ccc(O)c(Cl)c3)c2cc1OC	InChI=1S/C18H14ClN3O3/c1-24-16-6-12-14(7-17(16)25-2)21-9-10(8-20)18(12)22-11-3-4-15(23)13(19)5-11/h3-7,9,23H,1-2H3,(H,21,22)	DUDXBCAIXIMAKI-UHFFFAOYSA-N	4462	4-(3-Chloro-4-hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(3-chloro-4-hydroxyphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 25	Epidermal growth factor receptor	Homo sapiens		 9040							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4462&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328857	8034131							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6649	COc1cc2ncc(C#N)c(Nc3cc(Cl)c(O)c(Cl)c3)c2cc1OC	InChI=1S/C18H13Cl2N3O3/c1-25-15-5-11-14(6-16(15)26-2)22-8-9(7-21)17(11)23-10-3-12(19)18(24)13(20)4-10/h3-6,8,24H,1-2H3,(H,22,23)	YJBYKRFNOYCMSK-UHFFFAOYSA-N	4463	4-(3,5-Dichloro-4-hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(3,5-dichloro-4-hydroxyphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 26	Epidermal growth factor receptor	Homo sapiens		 3150							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4463&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328858	8034132							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6650	COc1cc2ncc(C#N)c(Nc3cc(Cl)ccc3O)c2cc1OC	InChI=1S/C18H14ClN3O3/c1-24-16-6-12-13(7-17(16)25-2)21-9-10(8-20)18(12)22-14-5-11(19)3-4-15(14)23/h3-7,9,23H,1-2H3,(H,21,22)	IVWBIVZBYRCUFO-UHFFFAOYSA-N	4464	4-[(5-chloro-2-hydroxyphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(5-Chloro-2-hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride::6,7-dialkoxyquinoline-3-carbonitrile deriv. 27	Epidermal growth factor receptor	Homo sapiens		 17020							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4464&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328859	8034133							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6651	COc1cc2ncc(C#N)c(Nc3cccc(SC)c3)c2cc1OC	InChI=1S/C19H17N3O2S/c1-23-17-8-15-16(9-18(17)24-2)21-11-12(10-20)19(15)22-13-5-4-6-14(7-13)25-3/h4-9,11H,1-3H3,(H,21,22)	ZSJDOQUXSFYFRM-UHFFFAOYSA-N	4465	6,7-Dimethoxy-4-(3-methylthiophenylamino)quinoline-3-carbonitrile Hydrochloride::6,7-dimethoxy-4-{[3-(methylsulfanyl)phenyl]amino}quinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 28	Epidermal growth factor receptor	Homo sapiens		 760							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4465&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328860	8034134							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6652	COc1cc2ncc(C#N)c(Nc3ccc(C)c(Cl)c3)c2cc1OC	InChI=1S/C19H16ClN3O2/c1-11-4-5-13(6-15(11)20)23-19-12(9-21)10-22-16-8-18(25-3)17(24-2)7-14(16)19/h4-8,10H,1-3H3,(H,22,23)	OSNTXNDDUYHOPC-UHFFFAOYSA-N	4466	4-[(3-chloro-4-methylphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(3-Chloro-4-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride::6,7-dialkoxyquinoline-3-carbonitrile deriv. 29	Epidermal growth factor receptor	Homo sapiens		 1480							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4466&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328861	8034135							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6653	COc1cc2ncc(C#N)c(Nc3ccc(Br)cc3F)c2cc1OC	InChI=1S/C18H13BrFN3O2/c1-24-16-6-12-15(7-17(16)25-2)22-9-10(8-21)18(12)23-14-4-3-11(19)5-13(14)20/h3-7,9H,1-2H3,(H,22,23)	ZGDAFEZSQVKBGC-UHFFFAOYSA-N	4467	4-[(4-bromo-2-fluorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(4-Bromo-2-fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride::6,7-dialkoxyquinoline-3-carbonitrile deriv. 30	Epidermal growth factor receptor	Homo sapiens		>91200							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4467&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328862	8034136							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6654	COc1cc2ncc(C#N)c(Nc3ccc(cc3)C(C)C)c2cc1OC	InChI=1S/C21H21N3O2/c1-13(2)14-5-7-16(8-6-14)24-21-15(11-22)12-23-18-10-20(26-4)19(25-3)9-17(18)21/h5-10,12-13H,1-4H3,(H,23,24)	GRSMJKZUNQCQJN-UHFFFAOYSA-N	4468	4-(4-Isopropylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dimethoxy-4-{[4-(propan-2-yl)phenyl]amino}quinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 31	Epidermal growth factor receptor	Homo sapiens		 230							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4468&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328863	8034137							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6655	COc1cc2ncc(C#N)c(Nc3ccccc3C(C)C)c2cc1OC	InChI=1S/C21H21N3O2/c1-13(2)15-7-5-6-8-17(15)24-21-14(11-22)12-23-18-10-20(26-4)19(25-3)9-16(18)21/h5-10,12-13H,1-4H3,(H,23,24)	DPCPGZUYFHEOOS-UHFFFAOYSA-N	4469	6,7-dimethoxy-4-{[2-(propan-2-yl)phenyl]amino}quinoline-3-carbonitrile::4-(2-Isopropylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 32	Epidermal growth factor receptor	Homo sapiens		 360							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4469&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328864	8034138							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6656	COc1cc2ncc(C#N)c(Nc3cccc(c3)C(C)C)c2cc1OC	InChI=1S/C21H21N3O2/c1-13(2)14-6-5-7-16(8-14)24-21-15(11-22)12-23-18-10-20(26-4)19(25-3)9-17(18)21/h5-10,12-13H,1-4H3,(H,23,24)	AMKUXKLKCBIHIX-UHFFFAOYSA-N	4470	6,7-dimethoxy-4-{[3-(propan-2-yl)phenyl]amino}quinoline-3-carbonitrile::4-(3-Isopropylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 33	Epidermal growth factor receptor	Homo sapiens		 62320							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4470&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328865	8034139							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6657	COc1cc2ncc(C#N)c(Nc3ccc(Br)cc3)c2cc1OC	InChI=1S/C18H14BrN3O2/c1-23-16-7-14-15(8-17(16)24-2)21-10-11(9-20)18(14)22-13-5-3-12(19)4-6-13/h3-8,10H,1-2H3,(H,21,22)	QDYBHXHSYKICNF-UHFFFAOYSA-N	4471	4-(4-Bromophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(4-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 34	Epidermal growth factor receptor	Homo sapiens		 6650							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4471&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328866	8034140							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6658	COc1cc2ncc(C#N)c(Nc3ccccc3Br)c2cc1OC	InChI=1S/C18H14BrN3O2/c1-23-16-7-12-15(8-17(16)24-2)21-10-11(9-20)18(12)22-14-6-4-3-5-13(14)19/h3-8,10H,1-2H3,(H,21,22)	JNLAWKYAXVEZSA-UHFFFAOYSA-N	4472	4-(2-Bromophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(2-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 35	Epidermal growth factor receptor	Homo sapiens		 4180							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4472&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328867	8034141							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6659	COc1cc2ncc(C#N)c(Nc3ccc(F)c(c3)C(F)(F)F)c2cc1OC	InChI=1S/C19H13F4N3O2/c1-27-16-6-12-15(7-17(16)28-2)25-9-10(8-24)18(12)26-11-3-4-14(20)13(5-11)19(21,22)23/h3-7,9H,1-2H3,(H,25,26)	JOFXBKKTSVGEOP-UHFFFAOYSA-N	4473	4-(4-Fluoro-3-trifluoromethylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride::4-{[4-fluoro-3-(trifluoromethyl)phenyl]amino}-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 36	Epidermal growth factor receptor	Homo sapiens		 160							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4473&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328868	8034142							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6660	COc1cc2ncc(C#N)c(Nc3cccc(Br)c3C)c2cc1OC	InChI=1S/C19H16BrN3O2/c1-11-14(20)5-4-6-15(11)23-19-12(9-21)10-22-16-8-18(25-3)17(24-2)7-13(16)19/h4-8,10H,1-3H3,(H,22,23)	PIFMNYYGBVDDCK-UHFFFAOYSA-N	4474	4-[(3-bromo-2-methylphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(3-Bromo-2-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 37	Epidermal growth factor receptor	Homo sapiens		 840							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4474	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4474&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328869	8034143							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6661	COc1cc2ncc(C#N)c(Nc3ccc(Br)c(C)c3)c2cc1OC	InChI=1S/C19H16BrN3O2/c1-11-6-13(4-5-15(11)20)23-19-12(9-21)10-22-16-8-18(25-3)17(24-2)7-14(16)19/h4-8,10H,1-3H3,(H,22,23)	MXOPSZOIOVSYKI-UHFFFAOYSA-N	4475	4-[(4-bromo-3-methylphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::4-(4-Bromo-3-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 38	Epidermal growth factor receptor	Homo sapiens		 620							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4475&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328870	8034144							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6662	COc1cc2ncc(C#N)c(Nc3cccc(c3)N=[N+]=[N-])c2cc1OC	InChI=1S/C18H14N6O2/c1-25-16-7-14-15(8-17(16)26-2)21-10-11(9-19)18(14)22-12-4-3-5-13(6-12)23-24-20/h3-8,10H,1-2H3,(H,21,22)	PVGQFSJIEXPGDS-UHFFFAOYSA-N	4476	4-(3-Azidophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::4-[(3-azidophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 39	Epidermal growth factor receptor	Homo sapiens		 2210							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4476&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328871	8034145							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6663	COc1cc2ncc(C#N)c(Nc3cccc(NC(C)=O)c3)c2cc1OC	InChI=1S/C20H18N4O3/c1-12(25)23-14-5-4-6-15(7-14)24-20-13(10-21)11-22-17-9-19(27-3)18(26-2)8-16(17)20/h4-9,11H,1-3H3,(H,22,24)(H,23,25)	ADTHOQASRLCLRF-UHFFFAOYSA-N	4477	N-{3-[(3-cyano-6,7-dimethoxyquinolin-4-yl)amino]phenyl}acetamide::N-[3-(3-Cyano-6,7-dimethoxyquinolin-4-ylamino)phenyl]acetamide::6,7-dialkoxyquinoline-3-carbonitrile deriv. 40	Epidermal growth factor receptor	Homo sapiens		 69400							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4477&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328872	8034146							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6664	CCOc1cc2c(Nc3cccc(Br)c3)c(cnc2cc1OC)C#N	InChI=1S/C19H16BrN3O2/c1-3-25-18-8-15-16(9-17(18)24-2)22-11-12(10-21)19(15)23-14-6-4-5-13(20)7-14/h4-9,11H,3H2,1-2H3,(H,22,23)	IKOYWGLBVGPRAG-UHFFFAOYSA-N	4478	4-[(3-bromophenyl)amino]-6-ethoxy-7-methoxyquinoline-3-carbonitrile::4-(3-Bromophenylamino)-6-ethoxy-7-methoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 48	Epidermal growth factor receptor	Homo sapiens		 21190							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4478	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4478&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328873	8034147							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6665	CCOc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C19H16BrN3O2/c1-3-25-18-9-16-15(8-17(18)24-2)19(12(10-21)11-22-16)23-14-6-4-5-13(20)7-14/h4-9,11H,3H2,1-2H3,(H,22,23)	WCNVEOXERDZIOX-UHFFFAOYSA-N	4479	4-[(3-bromophenyl)amino]-7-ethoxy-6-methoxyquinoline-3-carbonitrile::4-(3-Bromophenylamino)-7-ethoxy-6-methoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 49	Epidermal growth factor receptor	Homo sapiens		 33020							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4479&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328874	8034148							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6666	Brc1cccc(Nc2c(cnc3cc4OCCOc4cc23)C#N)c1	InChI=1S/C18H12BrN3O2/c19-12-2-1-3-13(6-12)22-18-11(9-20)10-21-15-8-17-16(7-14(15)18)23-4-5-24-17/h1-3,6-8,10H,4-5H2,(H,21,22)	XXZCQPXVPDUWAA-UHFFFAOYSA-N	4480	9-[(3-bromophenyl)amino]-2H,3H-[1,4]dioxino[2,3-g]quinoline-8-carbonitrile::9-(3-Bromophenylamino)-2,3-dihydro[1,4]dioxino[2,3-g]quinoline-8-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 50	Epidermal growth factor receptor	Homo sapiens		>104700							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4480	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4480&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328875	8034149							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6667	COc1cc2ncc(CO)c(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C18H17BrN2O3/c1-23-16-7-14-15(8-17(16)24-2)20-9-11(10-22)18(14)21-13-5-3-4-12(19)6-13/h3-9,22H,10H2,1-2H3,(H,20,21)	NMNOCAWQEQWSTF-UHFFFAOYSA-N	4481	{4-[(3-bromophenyl)amino]-6,7-dimethoxyquinolin-3-yl}methanol::[4-(3-Bromophenylamino)-6,7-dimethoxyquinolin-3-yl]-methanol::6,7-dialkoxyquinoline deriv. 51	Epidermal growth factor receptor	Homo sapiens		>102200							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4481&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328876	8034150							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6668	COc1cc2ncc(C=O)c(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C18H15BrN2O3/c1-23-16-7-14-15(8-17(16)24-2)20-9-11(10-22)18(14)21-13-5-3-4-12(19)6-13/h3-10H,1-2H3,(H,20,21)	ZCPJQXKRMPRGNF-UHFFFAOYSA-N	4482	4-[(3-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carbaldehyde::4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carbaldehyde::6,7-dialkoxyquinoline deriv. 52	Epidermal growth factor receptor	Homo sapiens		 3370							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4482&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328877	8034151							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6669	COc1cc2ncc(C(O)=O)c(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C18H15BrN2O4/c1-24-15-7-12-14(8-16(15)25-2)20-9-13(18(22)23)17(12)21-11-5-3-4-10(19)6-11/h3-9H,1-2H3,(H,20,21)(H,22,23)	CISJBDCCOIMBGW-UHFFFAOYSA-N	4483	4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carboxylic Acid::4-[(3-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carboxylic acid::6,7-dialkoxyquinoline deriv. 53	Epidermal growth factor receptor	Homo sapiens		 34220							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4483&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328878	8034152							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6670	COc1cc2ncc(C(N)=O)c(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C18H16BrN3O3/c1-24-15-7-12-14(8-16(15)25-2)21-9-13(18(20)23)17(12)22-11-5-3-4-10(19)6-11/h3-9H,1-2H3,(H2,20,23)(H,21,22)	SMPOMXVCIHTEMB-UHFFFAOYSA-N	4484	4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carboxylic Acid Amide::4-[(3-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carboxamide::6,7-dialkoxyquinoline deriv. 54	Epidermal growth factor receptor	Homo sapiens		 15170							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4484&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328879	8034153							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6671	Oc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1O	InChI=1S/C16H10BrN3O2/c17-10-2-1-3-11(4-10)20-16-9(7-18)8-19-13-6-15(22)14(21)5-12(13)16/h1-6,8,21-22H,(H,19,20)	UMAUXDSUHUAKMF-UHFFFAOYSA-N	4485	4-[(3-bromophenyl)amino]-6,7-dihydroxyquinoline-3-carbonitrile::4-(3-Bromophenylamino)-6,7-dihydroxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 55	Epidermal growth factor receptor	Homo sapiens		 350							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4485&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328880	8034154							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6672	COCOc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OCOC	InChI=1S/C20H18BrN3O4/c1-25-11-27-18-7-16-17(8-19(18)28-12-26-2)23-10-13(9-22)20(16)24-15-5-3-4-14(21)6-15/h3-8,10H,11-12H2,1-2H3,(H,23,24)	TUZMSVARIRHFNQ-UHFFFAOYSA-N	4486	4-[(3-bromophenyl)amino]-6,7-bis(methoxymethoxy)quinoline-3-carbonitrile::4-(3-Bromophenylamino)-6,7-bis(methoxymethoxy)-quinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 56	Epidermal growth factor receptor	Homo sapiens		 6750							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4486&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328881	8034155							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6673	COCCOc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OCCOC	InChI=1S/C22H22BrN3O4/c1-27-6-8-29-20-11-18-19(12-21(20)30-9-7-28-2)25-14-15(13-24)22(18)26-17-5-3-4-16(23)10-17/h3-5,10-12,14H,6-9H2,1-2H3,(H,25,26)	NVHCPPNJEXAXNA-UHFFFAOYSA-N	4487	4-[(3-bromophenyl)amino]-6,7-bis(2-methoxyethoxy)quinoline-3-carbonitrile::4-(3-Bromophenylamino)-6,7-bis(2-methoxyethoxy)-quinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 57	Epidermal growth factor receptor	Homo sapiens		 1100							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4487	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4487&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328882	8034156							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6674	Brc1cccc(Nc2c(cnc3cc4OCOc4cc23)C#N)c1	InChI=1S/C17H10BrN3O2/c18-11-2-1-3-12(4-11)21-17-10(7-19)8-20-14-6-16-15(5-13(14)17)22-9-23-16/h1-6,8H,9H2,(H,20,21)	AVKRWJGYHFZIQI-UHFFFAOYSA-N	4488	8-[(3-bromophenyl)amino]-2H-[1,3]dioxolo[4,5-g]quinoline-7-carbonitrile::8-(3-Bromophenylamino)[1,3]dioxolo[4,5-g]quinoline-7-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 58	Epidermal growth factor receptor	Homo sapiens		 6790							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4488	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4488&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328883	8034157							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6675	Brc1cccc(Nc2c(cnc3cc4OCCCOc4cc23)C#N)c1	InChI=1S/C19H14BrN3O2/c20-13-3-1-4-14(7-13)23-19-12(10-21)11-22-16-9-18-17(8-15(16)19)24-5-2-6-25-18/h1,3-4,7-9,11H,2,5-6H2,(H,22,23)	WGCFPJONRQWILN-UHFFFAOYSA-N	4489	4-(3-Bromophenylamino)-3,4-dihydro-2H-[1,4]dioxepino[2,3-g]quinoline-3-carbonitrile::10-[(3-bromophenyl)amino]-2H,3H,4H-[1,4]dioxepino[2,3-g]quinoline-9-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 59	Epidermal growth factor receptor	Homo sapiens		 5150							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4489&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328884	8034158							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6676	COc1cc2c(Nc3cccc(Br)c3)ncc(C#N)c2cc1OC	InChI=1S/C18H14BrN3O2/c1-23-16-7-14-11(9-20)10-21-18(15(14)8-17(16)24-2)22-13-5-3-4-12(19)6-13/h3-8,10H,1-2H3,(H,21,22)	KCTRDGYZIGFRDH-UHFFFAOYSA-N	4490	1-(3-Bromophenylamino)-6,7-dimethoxyisoquinoline-4-carbonitrile::1-[(3-bromophenyl)amino]-6,7-dimethoxyisoquinoline-4-carbonitrile::6,7-dimethoxyisoquinoline-4-carbonitrile deriv. 61	Epidermal growth factor receptor	Homo sapiens		 70840							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4490&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328885	8034159							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6677	COc1cc2c(Nc3cccc(Cl)c3)ncc(C#N)c2cc1OC	InChI=1S/C18H14ClN3O2/c1-23-16-7-14-11(9-20)10-21-18(15(14)8-17(16)24-2)22-13-5-3-4-12(19)6-13/h3-8,10H,1-2H3,(H,21,22)	FGOHOSIVNWPTCI-UHFFFAOYSA-N	4491	1-(3-Chlorophenylamino)-6,7-dimethoxyisoquinoline-4-carbonitrile::1-[(3-chlorophenyl)amino]-6,7-dimethoxyisoquinoline-4-carbonitrile::6,7-dimethoxyisoquinoline-4-carbonitrile deriv. 62	Epidermal growth factor receptor	Homo sapiens		 88290							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4491&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328886	8034160							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6678	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	LSPANGZZENHZNJ-UHFFFAOYSA-N	3032	CHEMBL29197::N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL1204168::PD153035::US9422297, PD153035::US11111252, Compound PD153035::US11001595, Compound PD153035	Epidermal growth factor receptor	Homo sapiens		 70							Curated from the literature by BindingDB	10.1021/jm000206a	10.7270/Q22V2D9M	10966743	aid1795638		Wissner, A; Berger, DM; Boschelli, DH; Floyd, MB; Greenberger, LM; Gruber, BC; Johnson, BD; Mamuya, N; Nilakantan, R; Reich, MF; Shen, R; Tsou, HR; Upeslacis, E; Wang, YF; Wu, B; Ye, F; Zhang, N	8/24/2000	5/17/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3032&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4705	8032779		CHEMBL1204168CHEMBL29197					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6753	CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3,5-11H,1H3,(H,22,24)(H,20,21,23)	BTYYWOYVBXILOJ-UHFFFAOYSA-N	4566	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide::CHEMBL91867::4-anilinoquinazoline deriv. 1	Epidermal growth factor receptor	Homo sapiens		 8					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4566&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2776	8034229		CHEMBL91867					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6754	C=CC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br	InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)	HTUBKQUPEREOGA-UHFFFAOYSA-N	4567	CHEMBL285063::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}prop-2-enamide::BMC163482 Compound 1::4-anilinoquinazoline deriv. 2::US9422297, PD168393	Epidermal growth factor receptor	Homo sapiens		 2					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4567	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4567&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	DJK	3LOK,4LQM,2J5F,2HWP	4708	8034230		CHEMBL285063	DB07662				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6755	CN(C)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C20H18BrN5O/c1-26(2)10-4-7-19(27)24-16-8-9-18-17(12-16)20(23-13-22-18)25-15-6-3-5-14(21)11-15/h3,5-6,8-9,11-13H,10H2,1-2H3,(H,24,27)(H,22,23,25)	OTMPOVZNMVTURI-UHFFFAOYSA-N	4568	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-ynamide::4-anilinoquinazoline deriv. 10a	Epidermal growth factor receptor	Homo sapiens		 6					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4568	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4568&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328954	8034231							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6756	CCN(CC)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C22H22BrN5O/c1-3-28(4-2)12-6-9-21(29)26-18-10-11-20-19(14-18)22(25-15-24-20)27-17-8-5-7-16(23)13-17/h5,7-8,10-11,13-15H,3-4,12H2,1-2H3,(H,26,29)(H,24,25,27)	RWRYVPUMPZVZSS-UHFFFAOYSA-N	4569	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(diethylamino)but-2-ynamide::4-anilinoquinazoline deriv. 10b	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4569&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328955	8034232							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6757	CCCN(CCC)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C24H26BrN5O/c1-3-12-30(13-4-2)14-6-9-23(31)28-20-10-11-22-21(16-20)24(27-17-26-22)29-19-8-5-7-18(25)15-19/h5,7-8,10-11,15-17H,3-4,12-14H2,1-2H3,(H,28,31)(H,26,27,29)	HYIYITLSLFGRPG-UHFFFAOYSA-N	4570	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dipropylamino)but-2-ynamide::4-anilinoquinazoline deriv. 10c	Epidermal growth factor receptor	Homo sapiens		 62					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4570&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328956	8034233							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6758	CC(C)N(C)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C22H22BrN5O/c1-15(2)28(3)11-5-8-21(29)26-18-9-10-20-19(13-18)22(25-14-24-20)27-17-7-4-6-16(23)12-17/h4,6-7,9-10,12-15H,11H2,1-3H3,(H,26,29)(H,24,25,27)	INNDLQJCKYFJTJ-UHFFFAOYSA-N	4571	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[methyl(propan-2-yl)amino]but-2-ynamide::4-anilinoquinazoline deriv. 10d	Epidermal growth factor receptor	Homo sapiens		 85					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4571	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4571&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328957	8034234							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6759	CC(C)N(CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)C(C)C	InChI=1S/C24H26BrN5O/c1-16(2)30(17(3)4)12-6-9-23(31)28-20-10-11-22-21(14-20)24(27-15-26-22)29-19-8-5-7-18(25)13-19/h5,7-8,10-11,13-17H,12H2,1-4H3,(H,28,31)(H,26,27,29)	OZIQEFLVKCIGLR-UHFFFAOYSA-N	4572	4-[bis(propan-2-yl)amino]-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide::4-anilinoquinazoline deriv. 10e	Epidermal growth factor receptor	Homo sapiens		 97					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4572&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328958	8034235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6760	CN(CC=C)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C22H20BrN5O/c1-3-11-28(2)12-5-8-21(29)26-18-9-10-20-19(14-18)22(25-15-24-20)27-17-7-4-6-16(23)13-17/h3-4,6-7,9-10,13-15H,1,11-12H2,2H3,(H,26,29)(H,24,25,27)	BFXGHOJOXUBCTO-UHFFFAOYSA-N	4573	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[methyl(prop-2-en-1-yl)amino]but-2-ynamide::4-anilinoquinazoline deriv. 10f	Epidermal growth factor receptor	Homo sapiens		 71					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4573	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4573&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328959	8034236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6761	Brc1cccc(Nc2ncnc3ccc(NC(=O)C#CCN4CCCCC4)cc23)c1	InChI=1S/C23H22BrN5O/c24-17-6-4-7-18(14-17)28-23-20-15-19(9-10-21(20)25-16-26-23)27-22(30)8-5-13-29-11-2-1-3-12-29/h4,6-7,9-10,14-16H,1-3,11-13H2,(H,27,30)(H,25,26,28)	BQMMBUOYOGSCCG-UHFFFAOYSA-N	4574	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(piperidin-1-yl)but-2-ynamide::4-anilinoquinazoline deriv. 10g	Epidermal growth factor receptor	Homo sapiens		 57					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4574&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328960	8034237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6762	Brc1cccc(Nc2ncnc3ccc(NC(=O)C#CCN4CCOCC4)cc23)c1	InChI=1S/C22H20BrN5O2/c23-16-3-1-4-17(13-16)27-22-19-14-18(6-7-20(19)24-15-25-22)26-21(29)5-2-8-28-9-11-30-12-10-28/h1,3-4,6-7,13-15H,8-12H2,(H,26,29)(H,24,25,27)	GGHZBUPPNLNXED-UHFFFAOYSA-N	4575	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(morpholin-4-yl)but-2-ynamide::4-anilinoquinazoline deriv. 10h	Epidermal growth factor receptor	Homo sapiens		 20					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4575	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4575&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328961	8034238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6763	Brc1cccc(Nc2ncnc3ccc(NC(=O)C#CCN4CCSCC4)cc23)c1	InChI=1S/C22H20BrN5OS/c23-16-3-1-4-17(13-16)27-22-19-14-18(6-7-20(19)24-15-25-22)26-21(29)5-2-8-28-9-11-30-12-10-28/h1,3-4,6-7,13-15H,8-12H2,(H,26,29)(H,24,25,27)	MXFUQFIEHKHLRL-UHFFFAOYSA-N	4576	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(thiomorpholin-4-yl)but-2-ynamide::4-anilinoquinazoline deriv. 10i	Epidermal growth factor receptor	Homo sapiens		 95					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4576&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328962	8034239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6764	COC[C@@H]1CCCN1CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |r|	InChI=1S/C24H24BrN5O2/c1-32-15-20-7-3-11-30(20)12-4-8-23(31)28-19-9-10-22-21(14-19)24(27-16-26-22)29-18-6-2-5-17(25)13-18/h2,5-6,9-10,13-14,16,20H,3,7,11-12,15H2,1H3,(H,28,31)(H,26,27,29)	RLNZIWVIDMGNEN-UHFFFAOYSA-N	4577	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-ynamide::4-anilinoquinazoline deriv. 10j	Epidermal growth factor receptor	Homo sapiens		 65					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4577&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328963	8034240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6765	CCN1CCN(CC#CC(=O)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)CC1	InChI=1S/C24H25BrN6O/c1-2-30-11-13-31(14-12-30)10-4-7-23(32)28-20-8-9-22-21(16-20)24(27-17-26-22)29-19-6-3-5-18(25)15-19/h3,5-6,8-9,15-17H,2,10-14H2,1H3,(H,28,32)(H,26,27,29)	JEZCURNCWCILAV-UHFFFAOYSA-N	4578	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(4-ethylpiperazin-1-yl)but-2-ynamide::4-anilinoquinazoline deriv. 10k	Epidermal growth factor receptor	Homo sapiens		 65					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4578&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328964	8034241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6766	COCC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C19H15BrN4O2/c1-26-9-3-6-18(25)23-15-7-8-17-16(11-15)19(22-12-21-17)24-14-5-2-4-13(20)10-14/h2,4-5,7-8,10-12H,9H2,1H3,(H,23,25)(H,21,22,24)	VKFHLVGNIPONMR-UHFFFAOYSA-N	4579	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-methoxybut-2-ynamide::4-anilinoquinazoline deriv. 10l	Epidermal growth factor receptor	Homo sapiens		 9					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4579&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328965	8034242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6767	COCCOCC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C21H19BrN4O3/c1-28-10-11-29-9-3-6-20(27)25-17-7-8-19-18(13-17)21(24-14-23-19)26-16-5-2-4-15(22)12-16/h2,4-5,7-8,12-14H,9-11H2,1H3,(H,25,27)(H,23,24,26)	WGYDIWMVEHEUEZ-UHFFFAOYSA-N	4580	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(2-methoxyethoxy)but-2-ynamide::4-anilinoquinazoline deriv. 10m	Epidermal growth factor receptor	Homo sapiens		 65					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4580	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4580&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328966	8034243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6768	COCOCC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C20H17BrN4O3/c1-27-13-28-9-3-6-19(26)24-16-7-8-18-17(11-16)20(23-12-22-18)25-15-5-2-4-14(21)10-15/h2,4-5,7-8,10-12H,9,13H2,1H3,(H,24,26)(H,22,23,25)	UCKKZOCKASQMFK-UHFFFAOYSA-N	4581	CHEMBL93049::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(methoxymethoxy)but-2-ynamide::4-anilinoquinazoline deriv. 10n	Epidermal growth factor receptor	Homo sapiens		 59					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4581	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4581&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328967	8034244		CHEMBL93049					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6769	OCC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H13BrN4O2/c19-12-3-1-4-13(9-12)23-18-15-10-14(22-17(25)5-2-8-24)6-7-16(15)20-11-21-18/h1,3-4,6-7,9-11,24H,8H2,(H,22,25)(H,20,21,23)	IHZHFIKEGVXLHF-UHFFFAOYSA-N	4582	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-hydroxybut-2-ynamide::4-anilinoquinazoline deriv. 10o	Epidermal growth factor receptor	Homo sapiens		 2					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4582&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328968	8034245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6770	CN(C)CC=CC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br	InChI=1S/C20H20BrN5O/c1-26(2)10-4-7-19(27)24-16-8-9-18-17(12-16)20(23-13-22-18)25-15-6-3-5-14(21)11-15/h3-9,11-13H,10H2,1-2H3,(H,24,27)(H,22,23,25)	ZCIXBBSRVLSRJQ-UHFFFAOYSA-N	4583	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide::CHEMBL94061::BMC163482 Compound 2::4-anilinoquinazoline deriv. 16a	Epidermal growth factor receptor	Homo sapiens		 11					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4583&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	SR2	2QQ7,2QLQ	5328969	8034246		CHEMBL94061	DB08564				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6771	CCN(CC)C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C22H24BrN5O/c1-3-28(4-2)12-6-9-21(29)26-18-10-11-20-19(14-18)22(25-15-24-20)27-17-8-5-7-16(23)13-17/h5-11,13-15H,3-4,12H2,1-2H3,(H,26,29)(H,24,25,27)	PJDCIIPPRINIGB-UHFFFAOYSA-N	4584	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(diethylamino)but-2-enamide::4-anilinoquinazoline deriv. 16b	Epidermal growth factor receptor	Homo sapiens		 73					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4584&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328970	8034247							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6772	CCCN(CCC)C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C24H28BrN5O/c1-3-12-30(13-4-2)14-6-9-23(31)28-20-10-11-22-21(16-20)24(27-17-26-22)29-19-8-5-7-18(25)15-19/h5-11,15-17H,3-4,12-14H2,1-2H3,(H,28,31)(H,26,27,29)	BLCWDFQAJUMTGJ-UHFFFAOYSA-N	4585	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dipropylamino)but-2-enamide::4-anilinoquinazoline deriv. 16c	Epidermal growth factor receptor	Homo sapiens		 90							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4585	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4585&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328971	8034248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6773	Brc1cccc(Nc2ncnc3ccc(NC(=O)\C=C\CN4CCCCC4)cc23)c1	InChI=1S/C23H24BrN5O/c24-17-6-4-7-18(14-17)28-23-20-15-19(9-10-21(20)25-16-26-23)27-22(30)8-5-13-29-11-2-1-3-12-29/h4-10,14-16H,1-3,11-13H2,(H,27,30)(H,25,26,28)	XDNJRZIUYRZKNY-UHFFFAOYSA-N	4586	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide::4-anilinoquinazoline deriv. 16g	Epidermal growth factor receptor	Homo sapiens		 106							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4586	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4586&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328972	8034249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6774	Brc1cccc(Nc2ncnc3ccc(NC(=O)\C=C\CN4CCOCC4)cc23)c1	InChI=1S/C22H22BrN5O2/c23-16-3-1-4-17(13-16)27-22-19-14-18(6-7-20(19)24-15-25-22)26-21(29)5-2-8-28-9-11-30-12-10-28/h1-7,13-15H,8-12H2,(H,26,29)(H,24,25,27)	OWNBJKMTBSDGLB-UHFFFAOYSA-N	4587	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(morpholin-4-yl)but-2-enamide::4-anilinoquinazoline deriv. 16h	Epidermal growth factor receptor	Homo sapiens		 74							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4587&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328973	8034250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6775	Brc1cccc(Nc2ncnc3ccc(NC(=O)\C=C\CN4CCSCC4)cc23)c1	InChI=1S/C22H22BrN5OS/c23-16-3-1-4-17(13-16)27-22-19-14-18(6-7-20(19)24-15-25-22)26-21(29)5-2-8-28-9-11-30-12-10-28/h1-7,13-15H,8-12H2,(H,26,29)(H,24,25,27)	WFWOGZGJIURUFA-UHFFFAOYSA-N	4588	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(thiomorpholin-4-yl)but-2-enamide::4-anilinoquinazoline deriv. 16i	Epidermal growth factor receptor	Homo sapiens		 203							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4588&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328974	8034251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6776	COC[C@@H]1CCCN1C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |r|	InChI=1S/C24H26BrN5O2/c1-32-15-20-7-3-11-30(20)12-4-8-23(31)28-19-9-10-22-21(14-19)24(27-16-26-22)29-18-6-2-5-17(25)13-18/h2,4-6,8-10,13-14,16,20H,3,7,11-12,15H2,1H3,(H,28,31)(H,26,27,29)	RHVQWSMLJGXEQH-UHFFFAOYSA-N	4589	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-enamide::4-anilinoquinazoline deriv. 16j	Epidermal growth factor receptor	Homo sapiens		 131							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4589&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328975	8034252							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6777	COC[C@H]1CCCN1C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |r|	InChI=1S/C24H26BrN5O2/c1-32-15-20-7-3-11-30(20)12-4-8-23(31)28-19-9-10-22-21(14-19)24(27-16-26-22)29-18-6-2-5-17(25)13-18/h2,4-6,8-10,13-14,16,20H,3,7,11-12,15H2,1H3,(H,28,31)(H,26,27,29)	RHVQWSMLJGXEQH-UHFFFAOYSA-N	4590	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-enamide::4-anilinoquinazoline deriv. 16p	Epidermal growth factor receptor	Homo sapiens		 85							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4590	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4590&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328976	8034253							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6778	COCCN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C22H24BrN5O2/c1-28(11-12-30-2)10-4-7-21(29)26-18-8-9-20-19(14-18)22(25-15-24-20)27-17-6-3-5-16(23)13-17/h3-9,13-15H,10-12H2,1-2H3,(H,26,29)(H,24,25,27)	BDNLTOXSGSRVFC-UHFFFAOYSA-N	4591	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[(2-methoxyethyl)(methyl)amino]but-2-enamide::4-anilinoquinazoline deriv. 16q	Epidermal growth factor receptor	Homo sapiens		 62							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4591	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4591&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328977	8034254							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6779	CN(CCO)C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C21H22BrN5O2/c1-27(10-11-28)9-3-6-20(29)25-17-7-8-19-18(13-17)21(24-14-23-19)26-16-5-2-4-15(22)12-16/h2-8,12-14,28H,9-11H2,1H3,(H,25,29)(H,23,24,26)	UFLUWNRWPWDTEF-UHFFFAOYSA-N	4592	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[(2-hydroxyethyl)(methyl)amino]but-2-enamide::4-anilinoquinazoline deriv. 16r	Epidermal growth factor receptor	Homo sapiens		 14							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4592	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4592&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328978	8034255							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6780	Brc1cccc(Nc2ncnc3ccc(NC(=O)\C=C\CN4CCC(CC4)N4CCCCC4)cc23)c1	InChI=1S/C28H33BrN6O/c29-21-6-4-7-22(18-21)33-28-25-19-23(9-10-26(25)30-20-31-28)32-27(36)8-5-13-34-16-11-24(12-17-34)35-14-2-1-3-15-35/h4-10,18-20,24H,1-3,11-17H2,(H,32,36)(H,30,31,33)	SSRSEBNRBASBBM-UHFFFAOYSA-N	4593	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[4-(piperidin-1-yl)piperidin-1-yl]but-2-enamide::4-anilinoquinazoline deriv. 16s	Epidermal growth factor receptor	Homo sapiens		 68							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4593	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4593&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328979	8034256							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6781	Brc1cccc(Nc2ncnc3ccc(NC(=O)\C=C\Cn4cccn4)cc23)c1	InChI=1S/C21H17BrN6O/c22-15-4-1-5-16(12-15)27-21-18-13-17(7-8-19(18)23-14-24-21)26-20(29)6-2-10-28-11-3-9-25-28/h1-9,11-14H,10H2,(H,26,29)(H,23,24,27)	UOQUXSNSYHWJQN-UHFFFAOYSA-N	4594	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(1H-pyrazol-1-yl)but-2-enamide::4-anilinoquinazoline deriv. 16t	Epidermal growth factor receptor	Homo sapiens		 1124							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4594&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328980	8034257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6782	CC(=C)C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H15BrN4O/c1-11(2)18(24)23-14-6-7-16-15(9-14)17(21-10-20-16)22-13-5-3-4-12(19)8-13/h3-10H,1H2,2H3,(H,23,24)(H,20,21,22)	YBGIIBLAQDXGRC-UHFFFAOYSA-N	4595	6-Substituted 4-Anilinoquinazoline 9::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-2-methylprop-2-enamide::4-anilinoquinazoline deriv. 17	Epidermal growth factor receptor	Homo sapiens		 339							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4595	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4595&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328981	8034258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6783	C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H15BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h2-11H,1H3,(H,22,24)(H,20,21,23)	JPHUTKJINPEEPQ-UHFFFAOYSA-N	4596	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-enamide::6-Substituted 4-Anilinoquinazoline 11::4-anilinoquinazoline deriv. 18	Epidermal growth factor receptor	Homo sapiens		 236							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4596&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328982	8034259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6784	COC\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C19H17BrN4O2/c1-26-9-3-6-18(25)23-15-7-8-17-16(11-15)19(22-12-21-17)24-14-5-2-4-13(20)10-14/h2-8,10-12H,9H2,1H3,(H,23,25)(H,21,22,24)	VHGGLPYMJXZJFI-UHFFFAOYSA-N	4597	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-methoxybut-2-enamide::4-anilinoquinazoline deriv. 19	Epidermal growth factor receptor	Homo sapiens		 1132							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4597&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328983	8034260							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6785	CN1CCC=C(C1)C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |c:4|	InChI=1S/C21H20BrN5O/c1-27-9-3-4-14(12-27)21(28)26-17-7-8-19-18(11-17)20(24-13-23-19)25-16-6-2-5-15(22)10-16/h2,4-8,10-11,13H,3,9,12H2,1H3,(H,26,28)(H,23,24,25)	QHSKAAHDPBBIMT-UHFFFAOYSA-N	4598	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-1-methyl-1,2,5,6-tetrahydropyridine-3-carboxamide::4-anilinoquinazoline deriv. 20	Epidermal growth factor receptor	Homo sapiens		 115							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4598	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4598&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328984	8034261							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6786	Brc1cccc(Nc2ncnc3ccc(NC(=O)C(=C)CN4CCOCC4)cc23)c1	InChI=1S/C22H22BrN5O2/c1-15(13-28-7-9-30-10-8-28)22(29)27-18-5-6-20-19(12-18)21(25-14-24-20)26-17-4-2-3-16(23)11-17/h2-6,11-12,14H,1,7-10,13H2,(H,27,29)(H,24,25,26)	VANCZLKVOHARGS-UHFFFAOYSA-N	4599	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-2-(morpholin-4-ylmethyl)prop-2-enamide::4-anilinoquinazoline deriv. 23	Epidermal growth factor receptor	Homo sapiens		 107							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4599	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4599&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328985	8034262							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6787	CN(C)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C19H18BrN5O/c1-25(2)9-8-18(26)23-15-6-7-17-16(11-15)19(22-12-21-17)24-14-5-3-4-13(20)10-14/h3-12H,1-2H3,(H,23,26)(H,21,22,24)	FSGPEDYXNUKDAG-UHFFFAOYSA-N	4600	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-3-(dimethylamino)prop-2-enamide::4-anilinoquinazoline deriv. 25a	Epidermal growth factor receptor	Homo sapiens		 250							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4600&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328986	8034263							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6788	Brc1cccc(Nc2ncnc3ccc(NC(=O)\C=C\N4CCOCC4)cc23)c1	InChI=1S/C21H20BrN5O2/c22-15-2-1-3-16(12-15)26-21-18-13-17(4-5-19(18)23-14-24-21)25-20(28)6-7-27-8-10-29-11-9-27/h1-7,12-14H,8-11H2,(H,25,28)(H,23,24,26)	AGTPOONMTANNPL-UHFFFAOYSA-N	4601	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-3-(morpholin-4-yl)prop-2-enamide::4-anilinoquinazoline deriv. 25h	Epidermal growth factor receptor	Homo sapiens		 215							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4601	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4601&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328987	8034264							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6789	C\C=C/C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H15BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h2-11H,1H3,(H,22,24)(H,20,21,23)	JPHUTKJINPEEPQ-UHFFFAOYSA-N	4602	(2Z)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-enamide::4-anilinoquinazoline deriv. 26	Epidermal growth factor receptor	Homo sapiens		 269							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4602	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4602&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328988	8034265							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
6790	COC[C@@H]1CCCN1C\C=C/C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |r|	InChI=1S/C24H26BrN5O2/c1-32-15-20-7-3-11-30(20)12-4-8-23(31)28-19-9-10-22-21(14-19)24(27-16-26-22)29-18-6-2-5-17(25)13-18/h2,4-6,8-10,13-14,16,20H,3,7,11-12,15H2,1H3,(H,28,31)(H,26,27,29)	RHVQWSMLJGXEQH-UHFFFAOYSA-N	4603	(2Z)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-enamide::4-anilinoquinazoline deriv. 27	Epidermal growth factor receptor	Homo sapiens		 194							Curated from the literature by BindingDB	10.1021/jm0005555	10.7270/Q2PN93TS	11495584	aid1795646		Tsou, HR; Mamuya, N; Johnson, BD; Reich, MF; Gruber, BC; Ye, F; Nilakantan, R; Shen, R; Discafani, C; DeBlanc, R; Davis, R; Koehn, FE; Greenberger, LM; Wang, YF; Wissner, A	8/16/2001	5/18/2005	Wyeth-Ayerst Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4603&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328989	8034266							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7068	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCn1ccnn1	InChI=1S/C19H16BrFN6O2/c1-28-17-9-13-16(10-18(17)29-7-6-27-5-4-24-26-27)22-11-23-19(13)25-15-3-2-12(20)8-14(15)21/h2-5,8-11H,6-7H2,1H3,(H,22,23,25)	YBTGTVGEKMZEQX-UHFFFAOYSA-N	4651	N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2,3-triazol-1-yl)ethoxy]quinazolin-4-amine::ZD4190	Epidermal growth factor receptor	Homo sapiens		 400						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4651&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329032	8034314							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7069	CN1CCC(CC1)COc2cc3c(cc2OC)c(ncn3)Nc4ccc(cc4F)Br	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	VANDETANIB::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::cid_3081361::ZD-6474::ZD6474::CHEMBL24828	Epidermal growth factor receptor	Homo sapiens		 500						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012		CHEMBL24828	DB08764				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7070	COCCOc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC	InChI=1S/C18H17ClFN3O3/c1-24-5-6-26-17-9-15-12(8-16(17)25-2)18(22-10-21-15)23-14-4-3-11(19)7-13(14)20/h3-4,7-10H,5-6H2,1-2H3,(H,21,22,23)	SWIHGAFGYUTAOY-UHFFFAOYSA-N	4628	KDR Kinase Inhibitor, 10::N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-(2-methoxyethoxy)-4-quinazolinylamine hydrochloride::CHEMBL286160::N-(4-chloro-2-fluorophenyl)-6-methoxy-7-(2-methoxyethoxy)quinazolin-4-amine::Anilinoquinazoline deriv. 11	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4628	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4628&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329011	8034291		CHEMBL286160					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7071	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCN1CCN(C)CC1	InChI=1S/C23H27ClFN5O2/c1-29-7-9-30(10-8-29)6-3-11-32-22-14-20-17(13-21(22)31-2)23(27-15-26-20)28-19-5-4-16(24)12-18(19)25/h4-5,12-15H,3,6-11H2,1-2H3,(H,26,27,28)	LSHMOEOLVFEUHJ-UHFFFAOYSA-N	4657	N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-amine::4-Anilinoquinazoline 4	Epidermal growth factor receptor	Homo sapiens		 75						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4657	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4657&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329035	8034318							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7072	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCCN1CCN(C)CC1	InChI=1S/C23H27BrFN5O2/c1-29-7-9-30(10-8-29)6-3-11-32-22-14-20-17(13-21(22)31-2)23(27-15-26-20)28-19-5-4-16(24)12-18(19)25/h4-5,12-15H,3,6-11H2,1-2H3,(H,26,27,28)	ZTHXTCUTPBRCGU-UHFFFAOYSA-N	4658	N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-amine::4-Anilinoquinazoline 5	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4658	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4658&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329036	8034319							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7073	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN1CCN(C)CC1	InChI=1S/C22H25ClFN5O2/c1-28-5-7-29(8-6-28)9-10-31-21-13-19-16(12-20(21)30-2)22(26-14-25-19)27-18-4-3-15(23)11-17(18)24/h3-4,11-14H,5-10H2,1-2H3,(H,25,26,27)	GSFNVLNOUTVLFC-UHFFFAOYSA-N	4659	N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-(4-methylpiperazin-1-yl)ethoxy]quinazolin-4-amine::4-Anilinoquinazoline 6	Epidermal growth factor receptor	Homo sapiens		 200						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4659	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4659&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4913175	8034320							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7074	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-12-16-19(13-21(20)31-8-2-5-28-6-9-30-10-7-28)25-14-26-22(16)27-18-4-3-15(23)11-17(18)24/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	JNAHSSCHKKAPHI-UHFFFAOYSA-N	4639	N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::4-Anilinoquinazoline 7::Anilinoquinazoline deriv. 22	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4639	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4639&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329020	8034302							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7075	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN1CCOCC1	InChI=1S/C21H22ClFN4O3/c1-28-19-11-15-18(12-20(19)30-9-6-27-4-7-29-8-5-27)24-13-25-21(15)26-17-3-2-14(22)10-16(17)23/h2-3,10-13H,4-9H2,1H3,(H,24,25,26)	WOSBEBRTYHKLTR-UHFFFAOYSA-N	4638	4-Anilinoquinazoline 8::N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(morpholin-4-yl)ethoxy]quinazolin-4-amine::Anilinoquinazoline deriv. 21	Epidermal growth factor receptor	Homo sapiens		 400						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4638	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4638&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329019	8034301							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7076	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCN1CCCC1	InChI=1S/C22H24ClFN4O2/c1-29-20-12-16-19(13-21(20)30-10-4-9-28-7-2-3-8-28)25-14-26-22(16)27-18-6-5-15(23)11-17(18)24/h5-6,11-14H,2-4,7-10H2,1H3,(H,25,26,27)	KQVFLNYZDGJFNM-UHFFFAOYSA-N	4662	N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine::N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-4-amine::4-Anilinoquinazoline 9	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4662&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329037	8034321							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7077	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OC\C=C\CN1CCCC1	InChI=1S/C23H24ClFN4O2/c1-30-21-13-17-20(14-22(21)31-11-5-4-10-29-8-2-3-9-29)26-15-27-23(17)28-19-7-6-16(24)12-18(19)25/h4-7,12-15H,2-3,8-11H2,1H3,(H,26,27,28)	BMEKKWWFQMYXPU-UHFFFAOYSA-N	4663	N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{[(2E)-4-(pyrrolidin-1-yl)but-2-en-1-yl]oxy}quinazolin-4-amine::N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-{[(2E)-4-pyrrolidin-1-ylbut-2-enyl]oxy}quinazolin-4-amine::4-Anilinoquinazoline 10	Epidermal growth factor receptor	Homo sapiens		 90						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4663	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4663&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329038	8034322							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7078	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC\C=C\CN1CCCC1	InChI=1S/C23H24BrFN4O2/c1-30-21-13-17-20(14-22(21)31-11-5-4-10-29-8-2-3-9-29)26-15-27-23(17)28-19-7-6-16(24)12-18(19)25/h4-7,12-15H,2-3,8-11H2,1H3,(H,26,27,28)	ZMAGOHAYMIZJEE-UHFFFAOYSA-N	4664	N-(4-bromo-2-fluorophenyl)-6-methoxy-7-{[(2E)-4-(pyrrolidin-1-yl)but-2-en-1-yl]oxy}quinazolin-4-amine::N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-{[(2E)-4-pyrrolidin-1-ylbut-2-enyl]oxy}quinazolin-4-amine::4-Anilinoquinazoline 11	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4664&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329039	8034323							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7079	COc1cc2c(Nc3ccc(cc3F)C#N)ncnc2cc1OC\C=C\CN1CCCC1	InChI=1S/C24H24FN5O2/c1-31-22-13-18-21(14-23(22)32-11-5-4-10-30-8-2-3-9-30)27-16-28-24(18)29-20-7-6-17(15-26)12-19(20)25/h4-7,12-14,16H,2-3,8-11H2,1H3,(H,27,28,29)	DIZVEEIWWJAIEW-UHFFFAOYSA-N	4665	3-fluoro-4-[(6-methoxy-7-{[(2E)-4-(pyrrolidin-1-yl)but-2-en-1-yl]oxy}quinazolin-4-yl)amino]benzonitrile::4-Anilinoquinazoline 12	Epidermal growth factor receptor	Homo sapiens		 800						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4665	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4665&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329040	8034324							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7080	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN(C)c1ccncc1	InChI=1S/C23H21ClFN5O2/c1-30(16-5-7-26-8-6-16)9-10-32-22-13-20-17(12-21(22)31-2)23(28-14-27-20)29-19-4-3-15(24)11-18(19)25/h3-8,11-14H,9-10H2,1-2H3,(H,27,28,29)	HTZZYCNEQVCJJB-UHFFFAOYSA-N	4645	N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{2-[methyl(pyridin-4-yl)amino]ethoxy}quinazolin-4-amine::4-Anilinoquinazoline 13::Anilinoquinazoline deriv. 28	Epidermal growth factor receptor	Homo sapiens		 300						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4645	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4645&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329026	8034308							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7081	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24ClFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	KNAJKXGUAHBQTI-UHFFFAOYSA-N	4668	N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::4-Anilinoquinazoline 15	Epidermal growth factor receptor	Homo sapiens		 300						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4668&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329041	8034325							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7082	COc1cc2c(Nc3ccc(C)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C23H27FN4O2/c1-15-4-5-19(18(24)10-15)27-23-17-11-21(29-3)22(12-20(17)25-14-26-23)30-13-16-6-8-28(2)9-7-16/h4-5,10-12,14,16H,6-9,13H2,1-3H3,(H,25,26,27)	WPCUQWCGLJALCN-UHFFFAOYSA-N	4669	N-(2-fluoro-4-methylphenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::N-(4-Methyl-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::4-Anilinoquinazoline 16	Epidermal growth factor receptor	Homo sapiens		 1000						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4669	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4669&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329042	8034326							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7083	COc1cc2c(Nc3cc(O)c(Cl)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24ClFN4O3/c1-28-5-3-13(4-6-28)11-31-21-10-17-14(7-20(21)30-2)22(26-12-25-17)27-18-9-19(29)15(23)8-16(18)24/h7-10,12-13,29H,3-6,11H2,1-2H3,(H,25,26,27)	HCAUEIOBSYOQPN-UHFFFAOYSA-N	4670	2-chloro-4-fluoro-5-({6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-yl}amino)phenol::4-Anilinoquinazoline 17	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4670	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4670&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329043	8034327							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7084	COc1cc2c(Nc3cc(O)c(C)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C23H27FN4O3/c1-14-8-17(24)19(10-20(14)29)27-23-16-9-21(30-3)22(11-18(16)25-13-26-23)31-12-15-4-6-28(2)7-5-15/h8-11,13,15,29H,4-7,12H2,1-3H3,(H,25,26,27)	SIABKVPDKZOJCK-UHFFFAOYSA-N	4671	4-fluoro-5-({6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-yl}amino)-2-methylphenol::4-Anilinoquinazoline 18	Epidermal growth factor receptor	Homo sapiens		 300						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4671	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4671&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329044	8034328							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7085	COc1cc2c(Nc3c(F)cc(Cl)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H23ClF2N4O2/c1-29-5-3-13(4-6-29)11-31-20-10-18-15(9-19(20)30-2)22(27-12-26-18)28-21-16(24)7-14(23)8-17(21)25/h7-10,12-13H,3-6,11H2,1-2H3,(H,26,27,28)	KQEHWOWUWGAOSR-UHFFFAOYSA-N	4672	N-(4-Chloro-2,6-difluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::4-Anilinoquinazoline 19	Epidermal growth factor receptor	Homo sapiens		 450						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4672	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4672&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329045	8034329							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7086	COc1cc2c(Nc3c(F)cc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H23BrF2N4O2/c1-29-5-3-13(4-6-29)11-31-20-10-18-15(9-19(20)30-2)22(27-12-26-18)28-21-16(24)7-14(23)8-17(21)25/h7-10,12-13H,3-6,11H2,1-2H3,(H,26,27,28)	KIWKXIDEBINNAK-UHFFFAOYSA-N	4673	N-(4-bromo-2,6-difluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::4-Anilinoquinazoline 20	Epidermal growth factor receptor	Homo sapiens		 300						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4673	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4673&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329046	8034330							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7087	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC1CCNCC1	InChI=1S/C21H22ClFN4O2/c1-28-19-9-15-18(10-20(19)29-11-13-4-6-24-7-5-13)25-12-26-21(15)27-17-3-2-14(22)8-16(17)23/h2-3,8-10,12-13,24H,4-7,11H2,1H3,(H,25,26,27)	AVQNSHZBOYOSQZ-UHFFFAOYSA-N	4674	N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine::4-Anilinoquinazoline 21	Epidermal growth factor receptor	Homo sapiens		 300						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4674	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4674&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329047	8034331							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7088	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCNCC1	InChI=1S/C21H22BrFN4O2/c1-28-19-9-15-18(10-20(19)29-11-13-4-6-24-7-5-13)25-12-26-21(15)27-17-3-2-14(22)8-16(17)23/h2-3,8-10,12-13,24H,4-7,11H2,1H3,(H,25,26,27)	HTCPERSEGREUFC-UHFFFAOYSA-N	4675	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine::4-Anilinoquinazoline 22	Epidermal growth factor receptor	Homo sapiens		 200						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4675	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4675&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329048	8034332							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7089	COc1cc2c(Nc3ccc(C)cc3F)ncnc2cc1OCC1CCNCC1	InChI=1S/C22H25FN4O2/c1-14-3-4-18(17(23)9-14)27-22-16-10-20(28-2)21(11-19(16)25-13-26-22)29-12-15-5-7-24-8-6-15/h3-4,9-11,13,15,24H,5-8,12H2,1-2H3,(H,25,26,27)	QAWSAMDJZZDGDW-UHFFFAOYSA-N	4676	N-(2-fluoro-4-methylphenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine::4-Anilinoquinazoline 23	Epidermal growth factor receptor	Homo sapiens		 500						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4676&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329049	8034333							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7090	COc1cc2c(Nc3c(F)cc(Cl)cc3F)ncnc2cc1OCC1CCNCC1	InChI=1S/C21H21ClF2N4O2/c1-29-18-8-14-17(9-19(18)30-10-12-2-4-25-5-3-12)26-11-27-21(14)28-20-15(23)6-13(22)7-16(20)24/h6-9,11-12,25H,2-5,10H2,1H3,(H,26,27,28)	FYZOPODRENDNJN-UHFFFAOYSA-N	4677	N-(4-chloro-2,6-difluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine::4-Anilinoquinazoline 24	Epidermal growth factor receptor	Homo sapiens		 500						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4677	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4677&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329050	8034334							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7091	COc1cc2c(Nc3c(F)cc(Br)cc3F)ncnc2cc1OCC1CCNCC1	InChI=1S/C21H21BrF2N4O2/c1-29-18-8-14-17(9-19(18)30-10-12-2-4-25-5-3-12)26-11-27-21(14)28-20-15(23)6-13(22)7-16(20)24/h6-9,11-12,25H,2-5,10H2,1H3,(H,26,27,28)	PBESGEKOQIKSKI-UHFFFAOYSA-N	4678	N-(4-bromo-2,6-difluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine::4-Anilinoquinazoline 25	Epidermal growth factor receptor	Homo sapiens		 450						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4678	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4678&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329051	8034335							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7092	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCC1CCN(C)CC1	InChI=1S/C23H26ClFN4O2/c1-29-8-5-15(6-9-29)7-10-31-22-13-20-17(12-21(22)30-2)23(27-14-26-20)28-19-4-3-16(24)11-18(19)25/h3-4,11-15H,5-10H2,1-2H3,(H,26,27,28)	VEOIWTSZBRXBQG-UHFFFAOYSA-N	4679	N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(1-methylpiperidin-4-yl)ethoxy]quinazolin-4-amine::4-Anilinoquinazoline 26	Epidermal growth factor receptor	Homo sapiens		 300						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4679	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4679&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329052	8034336							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7093	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCC1CCN(C)CC1	InChI=1S/C23H26BrFN4O2/c1-29-8-5-15(6-9-29)7-10-31-22-13-20-17(12-21(22)30-2)23(27-14-26-20)28-19-4-3-16(24)11-18(19)25/h3-4,11-15H,5-10H2,1-2H3,(H,26,27,28)	OORQGKRPXSYBAR-UHFFFAOYSA-N	4680	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[2-(1-methylpiperidin-4-yl)ethoxy]quinazolin-4-amine::4-Anilinoquinazoline 27	Epidermal growth factor receptor	Homo sapiens		 200						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4680	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4680&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329053	8034337							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7094	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCC1CCNCC1	InChI=1S/C22H24BrFN4O2/c1-29-20-11-16-19(12-21(20)30-9-6-14-4-7-25-8-5-14)26-13-27-22(16)28-18-3-2-15(23)10-17(18)24/h2-3,10-14,25H,4-9H2,1H3,(H,26,27,28)	ZESRALQQFCOMOY-UHFFFAOYSA-N	4681	N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[2-(piperidin-4-yl)ethoxy]quinazolin-4-amine::N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine::4-Anilinoquinazoline 28	Epidermal growth factor receptor	Homo sapiens		 200						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4681	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4681&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329054	8034338							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7095	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OC[C@@H]1CCCN(C)C1 |r|	InChI=1S/C22H24ClFN4O2/c1-28-7-3-4-14(11-28)12-30-21-10-19-16(9-20(21)29-2)22(26-13-25-19)27-18-6-5-15(23)8-17(18)24/h5-6,8-10,13-14H,3-4,7,11-12H2,1-2H3,(H,25,26,27)	OZVUSEVFXCWUBV-UHFFFAOYSA-N	4682	N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{[(3R)-1-methylpiperidin-3-yl]methoxy}quinazolin-4-amine::4-Anilinoquinazoline 29	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4682	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4682&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329055	8034339							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7096	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC[C@@H]1CCCN(C)C1 |r|	InChI=1S/C22H24BrFN4O2/c1-28-7-3-4-14(11-28)12-30-21-10-19-16(9-20(21)29-2)22(26-13-25-19)27-18-6-5-15(23)8-17(18)24/h5-6,8-10,13-14H,3-4,7,11-12H2,1-2H3,(H,25,26,27)	JFGLOXKNWPNMQT-UHFFFAOYSA-N	4683	N-(4-bromo-2-fluorophenyl)-6-methoxy-7-{[(3R)-1-methylpiperidin-3-yl]methoxy}quinazolin-4-amine::4-Anilinoquinazoline 30	Epidermal growth factor receptor	Homo sapiens		 200						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4683	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4683&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329056	8034340							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7097	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC[C@H]1CCCN(C)C1 |r|	InChI=1S/C22H24BrFN4O2/c1-28-7-3-4-14(11-28)12-30-21-10-19-16(9-20(21)29-2)22(26-13-25-19)27-18-6-5-15(23)8-17(18)24/h5-6,8-10,13-14H,3-4,7,11-12H2,1-2H3,(H,25,26,27)	JFGLOXKNWPNMQT-UHFFFAOYSA-N	4684	N-(4-bromo-2-fluorophenyl)-6-methoxy-7-{[(3S)-1-methylpiperidin-3-yl]methoxy}quinazolin-4-amine::4-Anilinoquinazoline 31	Epidermal growth factor receptor	Homo sapiens		 100						25.00 C	Curated from the literature by BindingDB	10.1021/jm011022e	10.7270/Q29C6VMW	11881999	aid1795660		Hennequin, LF; Stokes, ES; Thomas, AP; Johnstone, C; Ple, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO	3/14/2002	5/24/2005	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4684	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4684&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329057	8034341							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7246	Brc1cccc(Nc2ncnc3cnc(NC(=O)C=C)cc23)c1	InChI=1S/C16H12BrN5O/c1-2-15(23)22-14-7-12-13(8-18-14)19-9-20-16(12)21-11-5-3-4-10(17)6-11/h2-9H,1H2,(H,18,22,23)(H,19,20,21)	OLYVUTGQXNIQQG-UHFFFAOYSA-N	4777	N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}prop-2-enamide::CHEMBL51659::4-Anilinopyrido[3,4-d]pyrimidine 3	Epidermal growth factor receptor	Homo sapiens		 0.91					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4777&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329069	8034428		CHEMBL51659					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7247	C=CC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br	InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)	HTUBKQUPEREOGA-UHFFFAOYSA-N	4567	CHEMBL285063::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}prop-2-enamide::BMC163482 Compound 1::4-anilinoquinazoline deriv. 2::US9422297, PD168393	Epidermal growth factor receptor	Homo sapiens		 0.70					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4567	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4567&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	DJK	3LOK,4LQM,2J5F,2HWP	4708	8034230		CHEMBL285063	DB07662				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7248	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	cid_156414::PD0183805::CHEMBL545315::CHEMBL31965::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::CI-1033::US9730934, CI-1033::Canertinib::US10507209, Compound CI-1033	Epidermal growth factor receptor	Homo sapiens		 1.5					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429		CHEMBL31965CHEMBL545315	DB05424				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7249	CN(C(=O)C=C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C17H14BrN5O/c1-3-16(24)23(2)15-8-13-14(9-19-15)20-10-21-17(13)22-12-6-4-5-11(18)7-12/h3-10H,1H2,2H3,(H,20,21,22)	RCWLMTHCAVCUFY-UHFFFAOYSA-N	4780	N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-methylacrylamide::N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N-methylprop-2-enamide::4-Anilinopyrido[3,4-d]pyrimidine 7	Epidermal growth factor receptor	Homo sapiens		 0.17					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4780&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329070	8034430							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7250	CC(=C)C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C17H14BrN5O/c1-10(2)17(24)23-15-7-13-14(8-19-15)20-9-21-16(13)22-12-5-3-4-11(18)6-12/h3-9H,1H2,2H3,(H,19,23,24)(H,20,21,22)	UGKRCKRGEISAKC-UHFFFAOYSA-N	4781	N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-2-methylprop-2-enamide::N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-2-methylacrylamide::4-Anilinopyrido[3,4-d]pyrimidine 8	Epidermal growth factor receptor	Homo sapiens		 1.6					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4781	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4781&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329071	8034431							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7251	CC(=C)C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H15BrN4O/c1-11(2)18(24)23-14-6-7-16-15(9-14)17(21-10-20-16)22-13-5-3-4-12(19)8-13/h3-10H,1H2,2H3,(H,23,24)(H,20,21,22)	YBGIIBLAQDXGRC-UHFFFAOYSA-N	4595	6-Substituted 4-Anilinoquinazoline 9::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-2-methylprop-2-enamide::4-anilinoquinazoline deriv. 17	Epidermal growth factor receptor	Homo sapiens		 1.2					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4595	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4595&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328981	8034258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7252	C\C=C\C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C17H14BrN5O/c1-2-4-16(24)23-15-8-13-14(9-19-15)20-10-21-17(13)22-12-6-3-5-11(18)7-12/h2-10H,1H3,(H,19,23,24)(H,20,21,22)	PCRKFWDIMUJRAW-UHFFFAOYSA-N	4783	(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}but-2-enamide::(2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-2-butenamide::4-Anilinopyrido[3,4-d]pyrimidine 10	Epidermal growth factor receptor	Homo sapiens		 0.5					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4783&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329072	8034432							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7253	C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H15BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h2-11H,1H3,(H,22,24)(H,20,21,23)	JPHUTKJINPEEPQ-UHFFFAOYSA-N	4596	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-enamide::6-Substituted 4-Anilinoquinazoline 11::4-anilinoquinazoline deriv. 18	Epidermal growth factor receptor	Homo sapiens		 0.55					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4596&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328982	8034259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7254	Cl\C=C/C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C16H11BrClN5O/c17-10-2-1-3-11(6-10)22-16-12-7-14(23-15(24)4-5-18)19-8-13(12)20-9-21-16/h1-9H,(H,19,23,24)(H,20,21,22)	MNRDWWUGMJRIIM-UHFFFAOYSA-N	4785	(2Z)-N-[4-(3-Bromoanilino)-6-pyrido[3,4-d]pyrimidin-6-yl]-3-chloro-2-propenamide::(2Z)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-3-chloroprop-2-enamide::4-Anilinopyrido[3,4-d]pyrimidine 12	Epidermal growth factor receptor	Homo sapiens		 0.69					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4785&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329073	8034433							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7255	FC(F)(F)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H12BrF3N4O/c19-11-2-1-3-12(8-11)26-17-14-9-13(4-5-15(14)23-10-24-17)25-16(27)6-7-18(20,21)22/h1-10H,(H,25,27)(H,23,24,26)	IINXAWRVTBPNCW-UHFFFAOYSA-N	4786	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4,4,4-trifluorobut-2-enamide::(2E)-N-[4-(3-Bromoanilino)-6-quinazolinyl]-4,4,4-trifluoro-2-butenamide::6-Substituted 4-Anilinoquinazoline 13	Epidermal growth factor receptor	Homo sapiens		 1.75					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4786&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329074	8034434							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7256	Brc1cccc(Nc2ncnc3cnc(NC(=O)\C=C\C=C)cc23)c1	InChI=1S/C18H14BrN5O/c1-2-3-7-17(25)24-16-9-14-15(10-20-16)21-11-22-18(14)23-13-6-4-5-12(19)8-13/h2-11H,1H2,(H,20,24,25)(H,21,22,23)	UHUXAMBAPFKPGQ-UHFFFAOYSA-N	4787	(2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-2,4-pentadienamide::(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}penta-2,4-dienamide::4-Anilinopyrido[3,4-d]pyrimidine 14	Epidermal growth factor receptor	Homo sapiens		 1.1					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4787&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329075	8034435							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7257	Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C=C)cc23)c1	InChI=1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3-11H,1H2,(H,22,24)(H,20,21,23)	AWZOTLBLGSFFML-UHFFFAOYSA-N	4788	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}buta-2,3-dienamide::N-[4-(3-Bromoanilino)-6-quinazolinyl]-2,3-butadienamide::6-Substituted 4-Anilinoquinazoline 15	Epidermal growth factor receptor	Homo sapiens		 1.6					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4788	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4788&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329076	8034436							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7258	Brc1cccc(Nc2ncnc3cnc(NC(=O)\C=C\c4ccccc4)cc23)c1	InChI=1S/C22H16BrN5O/c23-16-7-4-8-17(11-16)27-22-18-12-20(24-13-19(18)25-14-26-22)28-21(29)10-9-15-5-2-1-3-6-15/h1-14H,(H,24,28,29)(H,25,26,27)	LECUYHDYEGPFIS-UHFFFAOYSA-N	4789	(2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-3-phenyl-2-propenamide::(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-3-phenylprop-2-enamide::4-Anilinopyrido[3,4-d]pyrimidine 16	Epidermal growth factor receptor	Homo sapiens		 9.1					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4789&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329077	8034437							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7259	CC(=O)C=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |w:4.4|	InChI=1S/C19H15BrN4O2/c1-12(25)5-8-18(26)23-15-6-7-17-16(10-15)19(22-11-21-17)24-14-4-2-3-13(20)9-14/h2-11H,1H3,(H,23,26)(H,21,22,24)	GOZHWVCSXUTKRE-UHFFFAOYSA-N	4790	(2E)-N-[4-(3-Bromoanilino)-6-quinazolinyl]-4-oxo-2-pentenamide::(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-oxopent-2-enamide::6-Substituted 4-Anilinoquinazoline 17	Epidermal growth factor receptor	Homo sapiens		 1.2					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4790	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4790&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329078	8034438							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7260	OC(=O)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C18H13BrN4O3/c19-11-2-1-3-12(8-11)23-18-14-9-13(4-5-15(14)20-10-21-18)22-16(24)6-7-17(25)26/h1-10H,(H,22,24)(H,25,26)(H,20,21,23)	DZDCQTBAAQYSND-UHFFFAOYSA-N	4791	(2E)-3-({4-[(3-bromophenyl)amino]quinazolin-6-yl}carbamoyl)prop-2-enoic acid::(2E)-4-{[4-(3-Bromoanilino)-6-quinazolinyl]amino}-4-oxo-2-butenoic Acid::6-Substituted 4-Anilinoquinazoline 18	Epidermal growth factor receptor	Homo sapiens		 0.37					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4791&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329079	8034439							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7261	CCOC(=O)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C20H17BrN4O3/c1-2-28-19(27)9-8-18(26)24-15-6-7-17-16(11-15)20(23-12-22-17)25-14-5-3-4-13(21)10-14/h3-12H,2H2,1H3,(H,24,26)(H,22,23,25)	VWESXNFYLQAEJY-UHFFFAOYSA-N	4792	ethyl (2E)-3-({4-[(3-bromophenyl)amino]quinazolin-6-yl}carbamoyl)prop-2-enoate::Ethyl (2E)-4-{[4-(3-Bromoanilino)-6-quinazolinyl]amino}-4-oxo-2-butenoate::6-Substituted 4-Anilinoquinazoline 19	Epidermal growth factor receptor	Homo sapiens		 2.7					7.4000	25.00 C	Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4792&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329080	8034440							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7262	CCOC(=O)\C=C\C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C19H16BrN5O3/c1-2-28-18(27)7-6-17(26)25-16-9-14-15(10-21-16)22-11-23-19(14)24-13-5-3-4-12(20)8-13/h3-11H,2H2,1H3,(H,21,25,26)(H,22,23,24)	GSAMPEADMMYOLW-UHFFFAOYSA-N	4793	ethyl (2E)-3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}carbamoyl)prop-2-enoate::Ethyl (2E)-4-{[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]amino}-4-oxo-2-butenoate::4-Anilinopyrido[3,4-d]pyrimidine 20	Epidermal growth factor receptor	Homo sapiens		 1.5							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4793	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4793&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329081	8034441							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7263	CN(C)CCN(C(=O)C=C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C20H21BrN6O/c1-4-19(28)27(9-8-26(2)3)18-11-16-17(12-22-18)23-13-24-20(16)25-15-7-5-6-14(21)10-15/h4-7,10-13H,1,8-9H2,2-3H3,(H,23,24,25)	JXKNVASLVHCEQV-UHFFFAOYSA-N	4794	N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-[2-(dimethylamino)ethyl]acrylamide::N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N-[2-(dimethylamino)ethyl]prop-2-enamide::4-Anilinopyrido[3,4-d]pyrimidine 21	Epidermal growth factor receptor	Homo sapiens		 4.2							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4794&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329082	8034442							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7264	Brc1cccc(Nc2ncnc3cnc(cc23)N(CCCN2CCOCC2)C(=O)C=C)c1	InChI=1S/C23H25BrN6O2/c1-2-22(31)30(8-4-7-29-9-11-32-12-10-29)21-14-19-20(15-25-21)26-16-27-23(19)28-18-6-3-5-17(24)13-18/h2-3,5-6,13-16H,1,4,7-12H2,(H,26,27,28)	OCBRGIXVRJXGMM-UHFFFAOYSA-N	4795	N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N-[3-(morpholin-4-yl)propyl]prop-2-enamide::N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-[3-(4-morpholinyl)propyl]acrylamide::4-Anilinopyrido[3,4-d]pyrimidine 22	Epidermal growth factor receptor	Homo sapiens		 2.7							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4795&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329083	8034443							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7265	Brc1cccc(Nc2ncnc3ccc(cc23)N(CCCN2CCOCC2)C(=O)C=C)c1	InChI=1S/C24H26BrN5O2/c1-2-23(31)30(10-4-9-29-11-13-32-14-12-29)20-7-8-22-21(16-20)24(27-17-26-22)28-19-6-3-5-18(25)15-19/h2-3,5-8,15-17H,1,4,9-14H2,(H,26,27,28)	FQAVYQDBRCNTBT-UHFFFAOYSA-N	4796	N-[4-(3-Bromoanilino)-6-quinazolinyl]-N-[3-(4-morpholinyl)propyl]acrylamide::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-N-[3-(morpholin-4-yl)propyl]prop-2-enamide::6-Substituted 4-Anilinoquinazoline 23	Epidermal growth factor receptor	Homo sapiens		 3.3							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4796&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329084	8034444							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7266	CN(C)CCCOC(=O)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C23H24BrN5O3/c1-29(2)11-4-12-32-22(31)10-9-21(30)27-18-7-8-20-19(14-18)23(26-15-25-20)28-17-6-3-5-16(24)13-17/h3,5-10,13-15H,4,11-12H2,1-2H3,(H,27,30)(H,25,26,28)	BBIKEXVBWCYZFP-UHFFFAOYSA-N	4797	3-(dimethylamino)propyl (2E)-3-({4-[(3-bromophenyl)amino]quinazolin-6-yl}carbamoyl)prop-2-enoate::3-(Dimethylamino)propyl (2E)-4-{[4-(3-Bromoanilino)-6-quinazolinyl]amino}-4-oxo-2-butenoate::6-Substituted 4-Anilinoquinazoline 24	Epidermal growth factor receptor	Homo sapiens		 2.4							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4797	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4797&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329085	8034445							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7267	CN(C)CCCNC(=O)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C23H25BrN6O2/c1-30(2)12-4-11-25-21(31)9-10-22(32)28-18-7-8-20-19(14-18)23(27-15-26-20)29-17-6-3-5-16(24)13-17/h3,5-10,13-15H,4,11-12H2,1-2H3,(H,25,31)(H,28,32)(H,26,27,29)	JKAXXKYYTNYYGM-UHFFFAOYSA-N	4798	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-N'-[3-(dimethylamino)propyl]but-2-enediamide::(2E)-N1-[4-(3-Bromoanilino)-6-quinazolinyl]-N4-[3-(dimethylamino)propyl]-2-butenediamide::6-Substituted 4-Anilinoquinazoline 25	Epidermal growth factor receptor	Homo sapiens		 0.44							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4798&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329086	8034446							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7268	CN(C)CCCNC(=O)\C=C\C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C22H24BrN7O2/c1-30(2)10-4-9-24-20(31)7-8-21(32)29-19-12-17-18(13-25-19)26-14-27-22(17)28-16-6-3-5-15(23)11-16/h3,5-8,11-14H,4,9-10H2,1-2H3,(H,24,31)(H,25,29,32)(H,26,27,28)	IDQAZRHOHYFAOQ-UHFFFAOYSA-N	4799	(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(dimethylamino)propyl]but-2-enediamide::(2E)-N1-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N4-[3-(dimethylamino)propyl]-2-butenediamide::4-Anilinopyrido[3,4-d]pyrimidine 26	Epidermal growth factor receptor	Homo sapiens		 1.1							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4799&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329087	8034447							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7269	CCN(CC)CCCNC(=O)\C=C\C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C24H28BrN7O2/c1-3-32(4-2)12-6-11-26-22(33)9-10-23(34)31-21-14-19-20(15-27-21)28-16-29-24(19)30-18-8-5-7-17(25)13-18/h5,7-10,13-16H,3-4,6,11-12H2,1-2H3,(H,26,33)(H,27,31,34)(H,28,29,30)	TYPAATJNKNDNOD-UHFFFAOYSA-N	4800	(2E)-N1-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N4-[3-(diethylamino)propyl]-2-butenediamide::(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(diethylamino)propyl]but-2-enediamide::4-Anilinopyrido[3,4-d]pyrimidine 27	Epidermal growth factor receptor	Homo sapiens		 0.73							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4800&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329088	8034448							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7270	Brc1cccc(Nc2ncnc3cnc(NC(=O)\C=C\C(=O)NCCCN4CCOCC4)cc23)c1	InChI=1S/C24H26BrN7O3/c25-17-3-1-4-18(13-17)30-24-19-14-21(27-15-20(19)28-16-29-24)31-23(34)6-5-22(33)26-7-2-8-32-9-11-35-12-10-32/h1,3-6,13-16H,2,7-12H2,(H,26,33)(H,27,31,34)(H,28,29,30)	JPHMUYSWHKPNKF-UHFFFAOYSA-N	4801	(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(morpholin-4-yl)propyl]but-2-enediamide::(2E)-N1-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N4-[3-(4-morpholinyl)propyl]-2-butenediamide::4-Anilinopyrido[3,4-d]pyrimidine 28	Epidermal growth factor receptor	Homo sapiens		 0.81							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4801&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329089	8034449							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7271	Brc1cccc(Nc2ncnc3cnc(NC(=O)\C=C\C(=O)NCCCn4ccnc4)cc23)c1	InChI=1S/C23H21BrN8O2/c24-16-3-1-4-17(11-16)30-23-18-12-20(27-13-19(18)28-14-29-23)31-22(34)6-5-21(33)26-7-2-9-32-10-8-25-15-32/h1,3-6,8,10-15H,2,7,9H2,(H,26,33)(H,27,31,34)(H,28,29,30)	RCQQOUGGIYVAKT-UHFFFAOYSA-N	4802	(2E)-N1-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N4-[3-(1H-imidazol-1-yl)propyl]-2-butenediamide::(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(1H-imidazol-1-yl)propyl]but-2-enediamide::4-Anilinopyrido[3,4-d]pyrimidine 29	Epidermal growth factor receptor	Homo sapiens		 0.56							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4802&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329090	8034450							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7272	CN(C)CCCNC(=O)\C=C\C(=O)N(C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C23H26BrN7O2/c1-30(2)11-5-10-25-21(32)8-9-22(33)31(3)20-13-18-19(14-26-20)27-15-28-23(18)29-17-7-4-6-16(24)12-17/h4,6-9,12-15H,5,10-11H2,1-3H3,(H,25,32)(H,27,28,29)	NXHJGHKRQJSQMH-UHFFFAOYSA-N	4803	(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(dimethylamino)propyl]-N''-methylbut-2-enediamide::(2E)-N1-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N4-[3-(dimethylamino)propyl]-N1-methyl-2-butenediamide::4-Anilinopyrido[3,4-d]pyrimidine 30	Epidermal growth factor receptor	Homo sapiens		 1.45							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4803&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329091	8034451							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7273	Fc1ccc(Nc2ncnc3cnc(NC(=O)\C=C\C(=O)NCCCN4CCOCC4)cc23)cc1Cl	InChI=1S/C24H25ClFN7O3/c25-18-12-16(2-3-19(18)26)31-24-17-13-21(28-14-20(17)29-15-30-24)32-23(35)5-4-22(34)27-6-1-7-33-8-10-36-11-9-33/h2-5,12-15H,1,6-11H2,(H,27,34)(H,28,32,35)(H,29,30,31)	KNXXEFGLJICDBL-UHFFFAOYSA-N	4804	(2E)-N1-[4-(3-Chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-N4-[3-(4-morpholinyl)propyl]-2-butenediamide::(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(morpholin-4-yl)propyl]but-2-enediamide::4-Anilinopyrido[3,4-d]pyrimidine 31	Epidermal growth factor receptor	Homo sapiens		 0.61							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4804&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329092	8034452							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7274	Brc1cccc(Nc2ncnc3cnc(NS(=O)(=O)C=C)cc23)c1	InChI=1S/C15H12BrN5O2S/c1-2-24(22,23)21-14-7-12-13(8-17-14)18-9-19-15(12)20-11-5-3-4-10(16)6-11/h2-9H,1H2,(H,17,21)(H,18,19,20)	DECUBVXBHCLQNY-UHFFFAOYSA-N	4805	N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}ethene-1-sulfonamide::N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]ethylenesulfonamide::4-Anilinopyrido[3,4-d]pyrimidine 32	Epidermal growth factor receptor	Homo sapiens		 0.76							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4805&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329093	8034453							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7275	Brc1cccc(Nc2ncnc3ccc(NS(=O)(=O)C=C)cc23)c1	InChI=1S/C16H13BrN4O2S/c1-2-24(22,23)21-13-6-7-15-14(9-13)16(19-10-18-15)20-12-5-3-4-11(17)8-12/h2-10,21H,1H2,(H,18,19,20)	XDSBIBMMFWAPMJ-UHFFFAOYSA-N	4806	N-[4-(3-Bromoanilino)-6-quinazolinyl]ethylenesulfonamide::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}ethene-1-sulfonamide::6-Substituted 4-Anilinoquinazoline 33	Epidermal growth factor receptor	Homo sapiens		 1.4							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4806&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329094	8034454							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7276	OCCS(=O)(=O)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1	InChI=1S/C15H13BrN4O3S/c16-10-2-1-3-11(6-10)20-15-12-7-14(24(22,23)5-4-21)17-8-13(12)18-9-19-15/h1-3,6-9,21H,4-5H2,(H,18,19,20)	XMBAKOAIBDXONF-UHFFFAOYSA-N	4807	2-{[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-sulfonyl}ethanol::2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidine-6-}sulfonyl)ethan-1-ol::4-Anilinopyrido[3,4-d]pyrimidine 34	Epidermal growth factor receptor	Homo sapiens		 93.5							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4807&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329095	8034455							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7277	Brc1cccc(Nc2ncnc3cnc(cc23)S(=O)(=O)C=C)c1	InChI=1S/C15H11BrN4O2S/c1-2-23(21,22)14-7-12-13(8-17-14)18-9-19-15(12)20-11-5-3-4-10(16)6-11/h2-9H,1H2,(H,18,19,20)	BNVCHCSZEJOIPQ-UHFFFAOYSA-N	4808	N-(3-Bromophenyl)-6-(vinylsulfonyl)pyrido[3,4-d]pyrimidin-4-amine::N-(3-bromophenyl)-6-(ethenesulfonyl)pyrido[3,4-d]pyrimidin-4-amine::4-Anilinopyrido[3,4-d]pyrimidine 35	Epidermal growth factor receptor	Homo sapiens		 0.43							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4808&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329096	8034456							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7278	Brc1cccc(Nc2ncnc3cnc(cc23)S(=O)C=C)c1	InChI=1S/C15H11BrN4OS/c1-2-22(21)14-7-12-13(8-17-14)18-9-19-15(12)20-11-5-3-4-10(16)6-11/h2-9H,1H2,(H,18,19,20)	UIYHGNBEHXNFBN-UHFFFAOYSA-N	4809	N-(3-Bromophenyl)-6-(vinylsulfinyl)pyrido[3,4-d]pyrimidin-4-amine::N-(3-bromophenyl)-6-(ethenesulfinyl)pyrido[3,4-d]pyrimidin-4-amine::4-Anilinopyrido[3,4-d]pyrimidine 36	Epidermal growth factor receptor	Homo sapiens		 4.6							Curated from the literature by BindingDB	10.1021/jm000372i	10.7270/Q2HX19WB	11462982	aid1795681		Smaill, JB; Showalter, HD; Zhou, H; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA	2/1/2001	6/2/2005	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4809&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329097	8034457							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7318	Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1	InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)	WUWDLXZGHZSWQZ-UHFFFAOYSA-N	4810	cid_5329098::CHEMBL276711::SU5146::(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one::SU5416::US9422297, SU5416::Semaxanib::US10189853, semaxanib::US11111252, Compound SU5416	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329098	8034458		CHEMBL276711					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7319	Cc1c(c([nH]c1/C=C\2/c3ccccc3NC2=O)C)CCC(=O)O	InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)	NHFDRBXTEDBWCZ-UHFFFAOYSA-N	4811	(Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid::CHEMBL274654::3-(2,4-dimethyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::SU6668	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4811&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	SU6	4JLC,5YVC	5329099	8034459		CHEMBL274654					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7320	CN1CCN(CCCc2c(C)[nH]c(\C=C3/C(=O)Nc4ccccc34)c2C)CC1	InChI=1S/C23H30N4O/c1-16-18(8-6-10-27-13-11-26(3)12-14-27)17(2)24-22(16)15-20-19-7-4-5-9-21(19)25-23(20)28/h4-5,7,9,15,24H,6,8,10-14H2,1-3H3,(H,25,28)	LPLGZUZPKACGSS-UHFFFAOYSA-N	4812	(3Z)-3-({3,5-dimethyl-4-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrol-2-yl}methylidene)-2,3-dihydro-1H-indol-2-one::SU5416 analog 5c	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4812&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329100	8034460							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7321	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccccc23)c1C	InChI=1S/C22H28N4O2/c1-5-26(6-2)12-11-23-22(28)20-14(3)19(24-15(20)4)13-17-16-9-7-8-10-18(16)25-21(17)27/h7-10,13,24H,5-6,11-12H2,1-4H3,(H,23,28)(H,25,27)	UJGXTMZILSGDLG-UHFFFAOYSA-N	4813	N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrole-3-carboxamide::SU11248 analog 12a	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4813&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329101	8034461							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7322	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C	InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)	WINHZLLDWRZWRT-UHFFFAOYSA-N	4814	SUNITINIB MALATE::CHEMBL535::N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU11248::N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::SUNITINIB::US9163010, Sunitinib::US9914707, SU11248::US10464902, Sunitinib::US20240058459, Compound Sunit-inib	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4814&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329102	8034462		CHEMBL535	DB01268				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7323	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(Cl)cc23)c1C	InChI=1S/C22H27ClN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)	XPLJEFSRINKZLC-UHFFFAOYSA-N	4815	5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::CHEMBL13485::SU11248 analog 12c::US10981896, Compound 572660	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4815&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329103	8034463		CHEMBL13485	DB08009				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7324	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(Br)cc23)c1C	InChI=1S/C22H27BrN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)	IVURVTQZRJNNOE-UHFFFAOYSA-N	4816	5-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU11248 analog 12d	Epidermal growth factor receptor	Homo sapiens		 10000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4816&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329104	8034464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7325	CN(C)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C	InChI=1S/C20H23FN4O2/c1-11-17(23-12(2)18(11)20(27)22-7-8-25(3)4)10-15-14-9-13(21)5-6-16(14)24-19(15)26/h5-6,9-10,23H,7-8H2,1-4H3,(H,22,27)(H,24,26)	MBTDIENWIYANIG-UHFFFAOYSA-N	4817	N-[2-(dimethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU11248 analog 12e	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4817&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329105	8034465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7326	Cc1c([nH]c(c1C(=O)NCCN2CCCC2)C)/C=C\3/c4cc(ccc4NC3=O)F	InChI=1S/C22H25FN4O2/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27/h5-6,11-12,25H,3-4,7-10H2,1-2H3,(H,24,29)(H,26,28)	SRSGVKWWVXWSJT-UHFFFAOYSA-N	4818	5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-N-[2-(pyrrolidin-1-yl)ethyl]-1H-pyrrole-3-carboxamide::SU11248 analog 12f	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4818&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	BWC	6M13	5329106	8034466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7327	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN1CCOCC1	InChI=1S/C22H25FN4O3/c1-13-19(12-17-16-11-15(23)3-4-18(16)26-21(17)28)25-14(2)20(13)22(29)24-5-6-27-7-9-30-10-8-27/h3-4,11-12,25H,5-10H2,1-2H3,(H,24,29)(H,26,28)	HGAQQKPBNGSIMU-UHFFFAOYSA-N	4820	5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-3-carboxamide::SU11248 analog 12h	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4820&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329108	8034468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7328	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCc1ccncc1	InChI=1S/C22H19FN4O2/c1-12-19(10-17-16-9-15(23)3-4-18(16)27-21(17)28)26-13(2)20(12)22(29)25-11-14-5-7-24-8-6-14/h3-10,26H,11H2,1-2H3,(H,25,29)(H,27,28)	DIKCCHQBRVVDJR-UHFFFAOYSA-N	4821	5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-N-(pyridin-4-ylmethyl)-1H-pyrrole-3-carboxamide::SU11248 analog 12i	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4821&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329109	8034469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7329	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCn1ccnn1	InChI=1S/C20H19FN6O2/c1-11-17(10-15-14-9-13(21)3-4-16(14)25-19(15)28)24-12(2)18(11)20(29)22-5-7-27-8-6-23-26-27/h3-4,6,8-10,24H,5,7H2,1-2H3,(H,22,29)(H,25,28)	GBLFVKOVMVPIQF-UHFFFAOYSA-N	4822	5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-N-[2-(1H-1,2,3-triazol-1-yl)ethyl]-1H-pyrrole-3-carboxamide::SU11248 analog 12j	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm0204183	10.7270/Q2D50K5B	12646019	aid1795684		Sun, L; Liang, C; Shirazian, S; Zhou, Y; Miller, T; Cui, J; Fukuda, JY; Chu, JY; Nematalla, A; Wang, X; Chen, H; Sistla, A; Luu, TC; Tang, F; Wei, J; Tang, C	3/27/2003	6/8/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4822&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329110	8034470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7574	Cc1c[nH]c(\C=C2/C(=O)Nc3ccccc23)c1CCC(O)=O	InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)	JNDVEAXZWJIOKB-UHFFFAOYSA-N	4882	3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::(Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)methylidenyl]indolin-2-one::CHEMBL89363::KDR Kinase Inhibitor, 5::SU5402	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4882	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4882&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5289418	8034525		CHEMBL89363	DB08577				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7575	Cc1c[nH]c(\C=C2/C(=O)Nc3cccc(C)c23)c1CCC(O)=O	InChI=1S/C18H18N2O3/c1-10-4-3-5-14-17(10)13(18(23)20-14)8-15-12(6-7-16(21)22)11(2)9-19-15/h3-5,8-9,19H,6-7H2,1-2H3,(H,20,23)(H,21,22)	WFEYKXAXXWJCGD-UHFFFAOYSA-N	4883	SU5402 analog 9a::3-(4-methyl-2-{[(3Z)-4-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 9a	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4883	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4883&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329134	8034526							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7576	Cc1c[nH]c(\C=C2/C(=O)Nc3ccc(Br)cc23)c1CCC(O)=O	InChI=1S/C17H15BrN2O3/c1-9-8-19-15(11(9)3-5-16(21)22)7-13-12-6-10(18)2-4-14(12)20-17(13)23/h2,4,6-8,19H,3,5H2,1H3,(H,20,23)(H,21,22)	MLCYRSPCPRZKNI-UHFFFAOYSA-N	4884	3-(2-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::SU5402 analog 9b::3-substituted indolin-2-one 9b	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4884	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4884&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329135	8034527							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7577	COc1cccc(c1)-c1ccc2\C(=C\c3[nH]cc(C)c3CCC(O)=O)C(=O)Nc2c1	InChI=1S/C24H22N2O4/c1-14-13-25-21(18(14)8-9-23(27)28)12-20-19-7-6-16(11-22(19)26-24(20)29)15-4-3-5-17(10-15)30-2/h3-7,10-13,25H,8-9H2,1-2H3,(H,26,29)(H,27,28)	JDISROKFUAYCBM-UHFFFAOYSA-N	4885	SU5402 analog 9c::3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 9c	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4885	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4885&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329136	8034528							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7578	CCOc1cccc(c1)-c1ccc2\C(=C\c3[nH]cc(C)c3CCC(O)=O)C(=O)Nc2c1	InChI=1S/C25H24N2O4/c1-3-31-18-6-4-5-16(11-18)17-7-8-20-21(25(30)27-23(20)12-17)13-22-19(9-10-24(28)29)15(2)14-26-22/h4-8,11-14,26H,3,9-10H2,1-2H3,(H,27,30)(H,28,29)	OYFXUFAPLNTDRA-UHFFFAOYSA-N	4886	3-(2-{[(3Z)-6-(3-ethoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::SU5402 analog 9d::3-substituted indolin-2-one 9d	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4886	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4886&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329137	8034529							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7579	Cc1c(CCC(O)=O)c[nH]c1\C=C1/C(=O)Nc2ccccc12	InChI=1S/C17H16N2O3/c1-10-11(6-7-16(20)21)9-18-15(10)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)	XZLCDAKBNFQCMU-UHFFFAOYSA-N	4887	3-(4-methyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::SU5402 analog 11a::3-[4-Methyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic Acid::3-substituted indolin-2-one 11a	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4887	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4887&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329138	8034530							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7580	Cc1c(CCC(O)=O)c[nH]c1\C=C1/C(=O)Nc2ccc(cc12)C(O)=O	InChI=1S/C18H16N2O5/c1-9-11(3-5-16(21)22)8-19-15(9)7-13-12-6-10(18(24)25)2-4-14(12)20-17(13)23/h2,4,6-8,19H,3,5H2,1H3,(H,20,23)(H,21,22)(H,24,25)	PBQQBKGLQWKLKQ-UHFFFAOYSA-N	4888	SU5402 analog 11b::3-[4-(2-Carboxyethyl)-3-methyl-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-carboxylic Acid::(3Z)-3-{[4-(2-carboxyethyl)-3-methyl-1H-pyrrol-2-yl]methylidene}-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid::3-substituted indolin-2-one 11b	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4888	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4888&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329139	8034531							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7581	Cc1c(CCC(O)=O)c[nH]c1\C=C1/C(=O)Nc2ccc(cc12)S(N)(=O)=O	InChI=1S/C17H17N3O5S/c1-9-10(2-5-16(21)22)8-19-15(9)7-13-12-6-11(26(18,24)25)3-4-14(12)20-17(13)23/h3-4,6-8,19H,2,5H2,1H3,(H,20,23)(H,21,22)(H2,18,24,25)	YLOCIDYFMMJTMC-UHFFFAOYSA-N	4889	3-(4-methyl-5-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::SU5402 analog 11c::3-[4-Methyl-5-(2-oxo-5-sulfamoyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic Acid::3-substituted indolin-2-one 11c	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4889	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4889&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329140	8034532							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7582	COc1ccc2\C(=C\c3[nH]cc(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C18H18N2O4/c1-10-11(3-6-17(21)22)9-19-15(10)8-14-13-5-4-12(24-2)7-16(13)20-18(14)23/h4-5,7-9,19H,3,6H2,1-2H3,(H,20,23)(H,21,22)	FTYXAWPLQFJPBB-UHFFFAOYSA-N	4890	3-(5-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::3-[5-(6-Methoxy-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-4-methyl-1H-pyrrol-3-yl]propionic Acid::SU5402 analog 11d::3-substituted indolin-2-one 11d	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4890	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4890&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329141	8034533							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7583	Cc1c(CCC(O)=O)c[nH]c1\C=C1/C(=O)Nc2cc(ccc12)-c1ccccc1	InChI=1S/C23H20N2O3/c1-14-17(8-10-22(26)27)13-24-20(14)12-19-18-9-7-16(11-21(18)25-23(19)28)15-5-3-2-4-6-15/h2-7,9,11-13,24H,8,10H2,1H3,(H,25,28)(H,26,27)	CEFJMJRPRONXNH-UHFFFAOYSA-N	4891	3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-[4-Methyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic Acid::SU5402 analog 11e::3-substituted indolin-2-one 11e	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4891	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4891&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329142	8034534							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7584	COc1cccc(c1)-c1ccc2\C(=C\c3[nH]cc(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C24H22N2O4/c1-14-17(7-9-23(27)28)13-25-21(14)12-20-19-8-6-16(11-22(19)26-24(20)29)15-4-3-5-18(10-15)30-2/h3-6,8,10-13,25H,7,9H2,1-2H3,(H,26,29)(H,27,28)	YAHVZVQVATYZMK-UHFFFAOYSA-N	4892	3-{5-[6-(3-Methoxy-phenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-4-methyl-1H-pyrrol-3-yl}propionic Acid::SU5402 analog 11f::3-(5-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 11f	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4892	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4892&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329143	8034535							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7585	COc1ccccc1-c1ccc2\C(=C\c3[nH]cc(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C24H22N2O4/c1-14-16(8-10-23(27)28)13-25-20(14)12-19-18-9-7-15(11-21(18)26-24(19)29)17-5-3-4-6-22(17)30-2/h3-7,9,11-13,25H,8,10H2,1-2H3,(H,26,29)(H,27,28)	IZKQKZYHPAYOKJ-UHFFFAOYSA-N	4893	3-{5-[6-(2-Methoxy-phenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-4-methyl-1H-pyrrol-3-yl}propionic Acid::3-(5-{[(3Z)-6-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::SU5402 analog 11g::3-substituted indolin-2-one 11g	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4893	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4893&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329144	8034536							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7586	COc1ccc(cc1)-c1ccc2\C(=C\c3[nH]cc(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C24H22N2O4/c1-14-17(6-10-23(27)28)13-25-21(14)12-20-19-9-5-16(11-22(19)26-24(20)29)15-3-7-18(30-2)8-4-15/h3-5,7-9,11-13,25H,6,10H2,1-2H3,(H,26,29)(H,27,28)	RDIYTLWMJLEVPM-UHFFFAOYSA-N	4894	3-(5-{[(3Z)-6-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid::SU5402 analog 11h::3-{5-[6-(4-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-4-methyl-1H-pyrrol-3-yl}propionic Acid::3-substituted indolin-2-one 11h	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4894	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4894&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329145	8034537							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7587	Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1	InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)	WUWDLXZGHZSWQZ-UHFFFAOYSA-N	4810	cid_5329098::CHEMBL276711::SU5146::(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one::SU5416::US9422297, SU5416::Semaxanib::US10189853, semaxanib::US11111252, Compound SU5416	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329098	8034458		CHEMBL276711					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7588	Cc1c(c([nH]c1/C=C\2/c3ccccc3NC2=O)C)CCC(=O)O	InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)	NHFDRBXTEDBWCZ-UHFFFAOYSA-N	4811	(Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid::CHEMBL274654::3-(2,4-dimethyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::SU6668	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4811&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	SU6	4JLC,5YVC	5329099	8034459		CHEMBL274654					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7589	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(Br)cc23)c(C)c1CCC(O)=O	InChI=1S/C18H17BrN2O3/c1-9-12(4-6-17(22)23)10(2)20-16(9)8-14-13-7-11(19)3-5-15(13)21-18(14)24/h3,5,7-8,20H,4,6H2,1-2H3,(H,21,24)(H,22,23)	CQXPYMNBBOWLME-UHFFFAOYSA-N	4896	3-(5-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 16b	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4896	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4896&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329146	8034538							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7590	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C(O)=O)c(C)c1CCC(O)=O	InChI=1S/C19H18N2O5/c1-9-12(4-6-17(22)23)10(2)20-16(9)8-14-13-7-11(19(25)26)3-5-15(13)21-18(14)24/h3,5,7-8,20H,4,6H2,1-2H3,(H,21,24)(H,22,23)(H,25,26)	AVQJNCBAUVLRRN-UHFFFAOYSA-N	4897	(3Z)-3-{[4-(2-carboxyethyl)-3,5-dimethyl-1H-pyrrol-2-yl]methylidene}-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid::3-substituted indolin-2-one 16c	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4897	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4897&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329147	8034539							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7591	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(N)(=O)=O)c(C)c1CCC(O)=O	InChI=1S/C18H19N3O5S/c1-9-12(4-6-17(22)23)10(2)20-16(9)8-14-13-7-11(27(19,25)26)3-5-15(13)21-18(14)24/h3,5,7-8,20H,4,6H2,1-2H3,(H,21,24)(H,22,23)(H2,19,25,26)	NCORNUPANAVMRQ-UHFFFAOYSA-N	4898	3-(2,4-dimethyl-5-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 16d	Epidermal growth factor receptor	Homo sapiens		 84800							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4898	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4898&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329148	8034540							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7592	COc1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C19H20N2O4/c1-10-13(6-7-18(22)23)11(2)20-16(10)9-15-14-5-4-12(25-3)8-17(14)21-19(15)24/h4-5,8-9,20H,6-7H2,1-3H3,(H,21,24)(H,22,23)	IYOHDJYJJGGYFL-UHFFFAOYSA-N	4899	3-(5-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 16e	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4899	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4899&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329149	8034541							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7593	Cc1[nH]c(\C=C2/C(=O)Nc3cc(ccc23)-c2ccccc2)c(C)c1CCC(O)=O	InChI=1S/C24H22N2O3/c1-14-18(10-11-23(27)28)15(2)25-21(14)13-20-19-9-8-17(12-22(19)26-24(20)29)16-6-4-3-5-7-16/h3-9,12-13,25H,10-11H2,1-2H3,(H,26,29)(H,27,28)	APYYTEJNOZQZNA-UHFFFAOYSA-N	4900	CHEMBL149201::3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 16f	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4900	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4900&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329150	8034542		CHEMBL149201					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7594	COc1cccc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C25H24N2O4/c1-14-19(9-10-24(28)29)15(2)26-22(14)13-21-20-8-7-17(12-23(20)27-25(21)30)16-5-4-6-18(11-16)31-3/h4-8,11-13,26H,9-10H2,1-3H3,(H,27,30)(H,28,29)	XLHWOGDAUMWGHR-UHFFFAOYSA-N	4901	3-(5-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::CHEMBL358728::3-substituted indolin-2-one 16g	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4901	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4901&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329151	8034543		CHEMBL358728					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7595	COc1ccccc1-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C25H24N2O4/c1-14-17(10-11-24(28)29)15(2)26-21(14)13-20-19-9-8-16(12-22(19)27-25(20)30)18-6-4-5-7-23(18)31-3/h4-9,12-13,26H,10-11H2,1-3H3,(H,27,30)(H,28,29)	MPBRWFJYTOVGPY-UHFFFAOYSA-N	4902	3-(5-{[(3Z)-6-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 16h	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4902	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4902&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329152	8034544							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7596	COc1ccc(cc1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1	InChI=1S/C25H24N2O4/c1-14-19(10-11-24(28)29)15(2)26-22(14)13-21-20-9-6-17(12-23(20)27-25(21)30)16-4-7-18(31-3)8-5-16/h4-9,12-13,26H,10-11H2,1-3H3,(H,27,30)(H,28,29)	JAKZLBJBNMIQMP-UHFFFAOYSA-N	4903	3-(5-{[(3Z)-6-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::3-substituted indolin-2-one 16i	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9904295	10.7270/Q20Z71GM	10602697	aid1795704		Sun, L; Tran, N; Liang, C; Tang, F; Rice, A; Schreck, R; Waltz, K; Shawver, LK; McMahon, G; Tang, C	12/16/1999	6/29/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4903	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4903&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329153	8034545							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7677	Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1	InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)	WUWDLXZGHZSWQZ-UHFFFAOYSA-N	4810	cid_5329098::CHEMBL276711::SU5146::(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one::SU5416::US9422297, SU5416::Semaxanib::US10189853, semaxanib::US11111252, Compound SU5416	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329098	8034458		CHEMBL276711					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7678	O=C1Nc2ccccc2\C1=C\c1cc2CCCCc2[nH]1	InChI=1S/C17H16N2O/c20-17-14(13-6-2-4-8-16(13)19-17)10-12-9-11-5-1-3-7-15(11)18-12/h2,4,6,8-10,18H,1,3,5,7H2,(H,19,20)	PEQAQVCHUDMZPB-UHFFFAOYSA-N	4904	(3Z)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::3-(4,5,6,7-Tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::Indolin-2-one deriv. 4a	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4904	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4904&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329154	8034546							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7679	Brc1ccc2NC(=O)\C(=C/c3cc4CCCCc4[nH]3)c2c1	InChI=1S/C17H15BrN2O/c18-11-5-6-16-13(8-11)14(17(21)20-16)9-12-7-10-3-1-2-4-15(10)19-12/h5-9,19H,1-4H2,(H,20,21)	RFHPWPWVGFSLOP-UHFFFAOYSA-N	4905	5-Bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::(3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::Indolin-2-one deriv. 4b	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4905	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4905&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329155	8034547							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7680	NS(=O)(=O)c1ccc2NC(=O)\C(=C/c3cc4CCCCc4[nH]3)c2c1	InChI=1S/C17H17N3O3S/c18-24(22,23)12-5-6-16-13(9-12)14(17(21)20-16)8-11-7-10-3-1-2-4-15(10)19-11/h5-9,19H,1-4H2,(H,20,21)(H2,18,22,23)	FHSRUXRMSRJDQV-UHFFFAOYSA-N	4906	2-Oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-2,3-dihydro-1H-indole-5-sulfonic Acid Amide::(3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indole-5-sulfonamide::Indolin-2-one deriv. 4c	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4906&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329156	8034548							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7681	OC(=O)c1ccc2NC(=O)\C(=C/c3cc4CCCCc4[nH]3)c2c1	InChI=1S/C18H16N2O3/c21-17-14(9-12-7-10-3-1-2-4-15(10)19-12)13-8-11(18(22)23)5-6-16(13)20-17/h5-9,19H,1-4H2,(H,20,21)(H,22,23)	CKNQIKAQBWDTIP-UHFFFAOYSA-N	4907	2-Oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-2,3-dihydro-1H-indole-5-carboxylic Acid::(3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indole-5-carboxylic acid::Indolin-2-one deriv. 4d	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4907	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4907&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329157	8034549							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7682	COc1ccc2\C(=C\c3cc4CCCCc4[nH]3)C(=O)Nc2c1	InChI=1S/C18H18N2O2/c1-22-13-6-7-14-15(18(21)20-17(14)10-13)9-12-8-11-4-2-3-5-16(11)19-12/h6-10,19H,2-5H2,1H3,(H,20,21)	FZYFCOVGBMTUON-UHFFFAOYSA-N	4908	(3Z)-6-methoxy-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::6-Methoxy-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::Indolin-2-one deriv. 4e	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4908&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329158	8034550							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7683	O=C1Nc2cc(ccc2\C1=C\c1cc2CCCCc2[nH]1)-c1ccccc1	InChI=1S/C23H20N2O/c26-23-20(14-18-12-17-8-4-5-9-21(17)24-18)19-11-10-16(13-22(19)25-23)15-6-2-1-3-7-15/h1-3,6-7,10-14,24H,4-5,8-9H2,(H,25,26)	BCEALSZPAPLOJG-UHFFFAOYSA-N	4909	(3Z)-6-phenyl-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::6-Phenyl-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::Indolin-2-one deriv. 4f	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4909	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4909&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329159	8034551							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7684	COc1cccc(c1)-c1ccc2\C(=C\c3cc4CCCCc4[nH]3)C(=O)Nc2c1	InChI=1S/C24H22N2O2/c1-28-19-7-4-6-15(12-19)16-9-10-20-21(24(27)26-23(20)13-16)14-18-11-17-5-2-3-8-22(17)25-18/h4,6-7,9-14,25H,2-3,5,8H2,1H3,(H,26,27)	NHBNPOFEIABVTF-UHFFFAOYSA-N	4910	(3Z)-6-(3-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::6-(3-Methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::Indolin-2-one deriv. 4g	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4910	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4910&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329160	8034552							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7685	COc1ccccc1-c1ccc2\C(=C\c3cc4CCCCc4[nH]3)C(=O)Nc2c1	InChI=1S/C24H22N2O2/c1-28-23-9-5-3-7-18(23)15-10-11-19-20(24(27)26-22(19)13-15)14-17-12-16-6-2-4-8-21(16)25-17/h3,5,7,9-14,25H,2,4,6,8H2,1H3,(H,26,27)	PFORQVNUDXKNNV-UHFFFAOYSA-N	4911	(3Z)-6-(2-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::6-(2-Methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::Indolin-2-one deriv. 4h	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4911	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4911&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329161	8034553							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7686	COc1ccc(cc1)-c1ccc2\C(=C\c3cc4CCCCc4[nH]3)C(=O)Nc2c1	InChI=1S/C24H22N2O2/c1-28-19-9-6-15(7-10-19)16-8-11-20-21(24(27)26-23(20)13-16)14-18-12-17-4-2-3-5-22(17)25-18/h6-14,25H,2-5H2,1H3,(H,26,27)	DPKWEIZIBQDTFF-UHFFFAOYSA-N	4912	(3Z)-6-(4-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::6-(4-Methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one::Indolin-2-one deriv. 4i	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4912	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4912&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329162	8034554							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7687	Cc1c[nH]c(\C=C2/C(=O)Nc3ccccc23)c1CCC(O)=O	InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)	JNDVEAXZWJIOKB-UHFFFAOYSA-N	4882	3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::(Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)methylidenyl]indolin-2-one::CHEMBL89363::KDR Kinase Inhibitor, 5::SU5402	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4882	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4882&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5289418	8034525		CHEMBL89363	DB08577				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7688	OC(=O)CCc1c(\C=C2/C(=O)Nc3ccccc23)[nH]c2CCCCc12	InChI=1S/C20H20N2O3/c23-19(24)10-9-14-12-5-1-3-7-16(12)21-18(14)11-15-13-6-2-4-8-17(13)22-20(15)25/h2,4,6,8,11,21H,1,3,5,7,9-10H2,(H,22,25)(H,23,24)	NPNOMACTPXEJJY-UHFFFAOYSA-N	4914	3-(2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-[2-(2-Oxo-1,2-dihydroindol-3-ylidenemethyl)-4,5,6,7-tetrahydro-1H-indol-3-yl]propionic Acid::Indolin-2-one deriv. 9a	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4914	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4914&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329163	8034555							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7689	OC(=O)CCc1c(\C=C2/C(=O)Nc3ccc(Br)cc23)[nH]c2CCCCc12	InChI=1S/C20H19BrN2O3/c21-11-5-7-17-14(9-11)15(20(26)23-17)10-18-13(6-8-19(24)25)12-3-1-2-4-16(12)22-18/h5,7,9-10,22H,1-4,6,8H2,(H,23,26)(H,24,25)	OICXIBPVOXVRBW-UHFFFAOYSA-N	4915	3-(2-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-[2-(5-Bromo-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-4,5,6,7-tetrahydro-1H-indol-3-yl]propionic Acid::Indolin-2-one deriv. 9b	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4915	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4915&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329164	8034556							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7690	NS(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c4CCCCc4c3CCC(O)=O)c2c1	InChI=1S/C20H21N3O5S/c21-29(27,28)11-5-7-17-14(9-11)15(20(26)23-17)10-18-13(6-8-19(24)25)12-3-1-2-4-16(12)22-18/h5,7,9-10,22H,1-4,6,8H2,(H,23,26)(H,24,25)(H2,21,27,28)	UYARELCPLIZIEQ-UHFFFAOYSA-N	4916	3-(2-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-[2-(2-Oxo-5-sulfamoyl-1,2-dihydroindol-3-ylidenemethyl)-4,5,6,7-tetrahydro-1H-indol-3-yl]propionic Acid::Indolin-2-one deriv. 9c	Epidermal growth factor receptor	Homo sapiens		 29100							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4916	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4916&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329165	8034557							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7691	OC(=O)CCc1c(\C=C2/C(=O)Nc3ccc(cc23)C(O)=O)[nH]c2CCCCc12	InChI=1S/C21H20N2O5/c24-19(25)8-6-13-12-3-1-2-4-16(12)22-18(13)10-15-14-9-11(21(27)28)5-7-17(14)23-20(15)26/h5,7,9-10,22H,1-4,6,8H2,(H,23,26)(H,24,25)(H,27,28)	WEEGIHLRCOYVPM-UHFFFAOYSA-N	4917	(3Z)-3-{[3-(2-carboxyethyl)-4,5,6,7-tetrahydro-1H-indol-2-yl]methylidene}-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid::3-[3-(2-Carboxyethyl)-4,5,6,7-tetrahydro-1H-indol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-carboxylic Acid::Indolin-2-one deriv. 9d	Epidermal growth factor receptor	Homo sapiens		 56500							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4917	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4917&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329166	8034558							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7692	COc1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1	InChI=1S/C21H22N2O4/c1-27-12-6-7-15-16(21(26)23-18(15)10-12)11-19-14(8-9-20(24)25)13-4-2-3-5-17(13)22-19/h6-7,10-11,22H,2-5,8-9H2,1H3,(H,23,26)(H,24,25)	QKVUBIOLQLJVKI-UHFFFAOYSA-N	4918	3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::Indolin-2-one deriv. 9e	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4918	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4918&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329167	8034559							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7693	OC(=O)CCc1c(\C=C2/C(=O)Nc3cc(ccc23)-c2ccccc2)[nH]c2CCCCc12	InChI=1S/C26H24N2O3/c29-25(30)13-12-19-18-8-4-5-9-22(18)27-24(19)15-21-20-11-10-17(14-23(20)28-26(21)31)16-6-2-1-3-7-16/h1-3,6-7,10-11,14-15,27H,4-5,8-9,12-13H2,(H,28,31)(H,29,30)	NQIZOXPPUYQOQV-UHFFFAOYSA-N	4919	3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-[2-(2-Oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-4,5,6,7-tetrahydro-1H-indol-3-yl]propionic Acid::Indolin-2-one deriv. 9f	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4919&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329168	8034560							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7694	COc1cccc(c1)-c1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1	InChI=1S/C27H26N2O4/c1-33-18-6-4-5-16(13-18)17-9-10-21-22(27(32)29-24(21)14-17)15-25-20(11-12-26(30)31)19-7-2-3-8-23(19)28-25/h4-6,9-10,13-15,28H,2-3,7-8,11-12H2,1H3,(H,29,32)(H,30,31)	FUXHNAHZJZOIIP-UHFFFAOYSA-N	4920	3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3ylidenemethyl]-4,5,6,7-tetrahydro-1H-indol-3-yl}-propionic Acid::3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::Indolin-2-one deriv. 9g	Epidermal growth factor receptor	Homo sapiens		 8880							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4920	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4920&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329169	8034561							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7695	COc1ccccc1-c1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1	InChI=1S/C27H26N2O4/c1-33-25-9-5-3-6-17(25)16-10-11-20-21(27(32)29-23(20)14-16)15-24-19(12-13-26(30)31)18-7-2-4-8-22(18)28-24/h3,5-6,9-11,14-15,28H,2,4,7-8,12-13H2,1H3,(H,29,32)(H,30,31)	JROBWQZZQGDCLF-UHFFFAOYSA-N	4921	3-(2-{[(3Z)-6-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-{2-[6-(2-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-4,5,6,7-tetrahydro-1H-indol-3-yl}-propionic Acid::Indolin-2-one deriv. 9h	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4921	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4921&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329170	8034562							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
7696	COc1ccc(cc1)-c1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1	InChI=1S/C27H26N2O4/c1-33-18-9-6-16(7-10-18)17-8-11-21-22(27(32)29-24(21)14-17)15-25-20(12-13-26(30)31)19-4-2-3-5-23(19)28-25/h6-11,14-15,28H,2-5,12-13H2,1H3,(H,29,32)(H,30,31)	IEDHIXOGGAHSLI-UHFFFAOYSA-N	4922	3-(2-{[(3Z)-6-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-{2-[6-(4-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-4,5,6,7-tetrahydro-1H-indol-3-yl}-propionic Acid::Indolin-2-one deriv. 9i	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm9906116	10.7270/Q2W66J0N	10893303	aid1795712		Sun, L; Tran, N; Liang, C; Hubbard, S; Tang, F; Lipson, K; Schreck, R; Zhou, Y; McMahon, G; Tang, C	7/13/2000	6/16/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4922	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4922&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329171	8034563							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8202	Fc1ccc(Nc2ncnc3NC(=O)\C(=C/c4ccc[nH]4)c23)cc1Cl	InChI=1S/C17H11ClFN5O/c18-12-7-10(3-4-13(12)19)23-15-14-11(6-9-2-1-5-20-9)17(25)24-16(14)22-8-21-15/h1-8,20H,(H2,21,22,23,24,25)	GJJATVDARFZDOM-UHFFFAOYSA-N	5123	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-(1H-pyrrol-2-ylmethylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26a	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5123	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5123&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329229	8034760							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8203	Cc1[nH]c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)c(C)c1CCC(O)=O	InChI=1S/C22H19ClFN5O3/c1-10-13(4-6-18(30)31)11(2)27-17(10)8-14-19-20(25-9-26-21(19)29-22(14)32)28-12-3-5-16(24)15(23)7-12/h3,5,7-9,27H,4,6H2,1-2H3,(H,30,31)(H2,25,26,28,29,32)	GDKHQUDZTDIVIZ-UHFFFAOYSA-N	5124	3-(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26b	Epidermal growth factor receptor	Homo sapiens		 180							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5124	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5124&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329230	8034761							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8204	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)c1C	InChI=1S/C26H29ClFN7O2/c1-5-35(6-2)10-9-29-26(37)21-14(3)20(32-15(21)4)12-17-22-23(30-13-31-24(22)34-25(17)36)33-16-7-8-19(28)18(27)11-16/h7-8,11-13,32H,5-6,9-10H2,1-4H3,(H,29,37)(H2,30,31,33,34,36)	DYAPCMBXNXESMW-UHFFFAOYSA-N	5125	5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26c	Epidermal growth factor receptor	Homo sapiens		 200							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5125	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5125&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329231	8034762							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8205	Cc1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)[nH]1	InChI=1S/C19H15ClFN5O/c1-9-5-10(2)24-15(9)7-12-16-17(22-8-23-18(16)26-19(12)27)25-11-3-4-14(21)13(20)6-11/h3-8,24H,1-2H3,(H2,22,23,25,26,27)	YFDRVUYGJJBGOU-UHFFFAOYSA-N	5126	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26d	Epidermal growth factor receptor	Homo sapiens		 41							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5126	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5126&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329232	8034763							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8206	Cc1cc(CCC(O)=O)[nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c12	InChI=1S/C21H17ClFN5O3/c1-10-6-11(3-5-17(29)30)26-16(10)8-13-18-19(24-9-25-20(18)28-21(13)31)27-12-2-4-15(23)14(22)7-12/h2,4,6-9,26H,3,5H2,1H3,(H,29,30)(H2,24,25,27,28,31)	QKAUOZDTEZWAOG-UHFFFAOYSA-N	5127	3-(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-1H-pyrrol-2-yl)propanoic acid::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26e	Epidermal growth factor receptor	Homo sapiens		 4.7							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5127	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5127&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329233	8034764							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8207	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c12)C(O)=O	InChI=1S/C19H13ClFN5O3/c1-8-4-14(19(28)29)25-13(8)6-10-15-16(22-7-23-17(15)26-18(10)27)24-9-2-3-12(21)11(20)5-9/h2-7,25H,1H3,(H,28,29)(H2,22,23,24,26,27)	QQRLVNGJKMMEMW-UHFFFAOYSA-N	5128	5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-1H-pyrrole-2-carboxylic acid::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26f	Epidermal growth factor receptor	Homo sapiens		 29							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5128	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5128&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329234	8034765							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8208	Fc1ccc(Nc2ncnc3NC(=O)\C(=C/c4ccc([nH]4)C(=O)NCCN4CCOCC4)c23)cc1Cl	InChI=1S/C24H23ClFN7O3/c25-17-12-15(1-3-18(17)26)31-21-20-16(23(34)32-22(20)29-13-28-21)11-14-2-4-19(30-14)24(35)27-5-6-33-7-9-36-10-8-33/h1-4,11-13,30H,5-10H2,(H,27,35)(H2,28,29,31,32,34)	YXYOPRGOSTYKLY-UHFFFAOYSA-N	5129	5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26g	Epidermal growth factor receptor	Homo sapiens		 22							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5129	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5129&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329235	8034766							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8209	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c12)C(=O)NCCN1CCOCC1	InChI=1S/C25H25ClFN7O3/c1-14-10-20(25(36)28-4-5-34-6-8-37-9-7-34)32-19(14)12-16-21-22(29-13-30-23(21)33-24(16)35)31-15-2-3-18(27)17(26)11-15/h2-3,10-13,32H,4-9H2,1H3,(H,28,36)(H2,29,30,31,33,35)	OLURIASFBDWIAK-UHFFFAOYSA-N	5130	5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26h	Epidermal growth factor receptor	Homo sapiens		 6.5							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5130	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5130&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329236	8034767							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8210	CN1C(=O)\C(=C/c2[nH]c(C)cc2C)c2c1ncnc2Nc1ccc(F)c(Cl)c1	InChI=1S/C20H17ClFN5O/c1-10-6-11(2)25-16(10)8-13-17-18(23-9-24-19(17)27(3)20(13)28)26-12-4-5-15(22)14(21)7-12/h4-9,25H,1-3H3,(H,23,24,26)	WAYQKXZMUDFDDG-UHFFFAOYSA-N	5131	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-7-methyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26i	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5131	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5131&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329237	8034768							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8211	CN1C(=O)\C(=C/c2[nH]c(cc2C)C(=O)NCCN2CCOCC2)c2c1ncnc2Nc1ccc(F)c(Cl)c1	InChI=1S/C26H27ClFN7O3/c1-15-11-21(25(36)29-5-6-35-7-9-38-10-8-35)33-20(15)13-17-22-23(30-14-31-24(22)34(2)26(17)37)32-16-3-4-19(28)18(27)12-16/h3-4,11-14,33H,5-10H2,1-2H3,(H,29,36)(H,30,31,32)	VZVRWQGDDKSERZ-UHFFFAOYSA-N	5132	5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-7-methyl-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26j	Epidermal growth factor receptor	Homo sapiens		 5310							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5132	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5132&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329238	8034769							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8212	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c12)C(=O)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-12-8-18(23(33)31-4-6-34-7-5-31)29-17(12)10-14-19-20(26-11-27-21(19)30-22(14)32)28-13-2-3-16(25)15(24)9-13/h2-3,8-11,29H,4-7H2,1H3,(H2,26,27,28,30,32)	JQPOKKSPLVGJGJ-UHFFFAOYSA-N	5133	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26k	Epidermal growth factor receptor	Homo sapiens		 170							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5133	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5133&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329239	8034770							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8213	CN1CCN(CC1)C(=O)c1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)[nH]1	InChI=1S/C24H23ClFN7O2/c1-13-9-19(24(35)33-7-5-32(2)6-8-33)30-18(13)11-15-20-21(27-12-28-22(20)31-23(15)34)29-14-3-4-17(26)16(25)10-14/h3-4,9-12,30H,5-8H2,1-2H3,(H2,27,28,29,31,34)	FNFNGVSJMJREKW-UHFFFAOYSA-N	5134	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26l	Epidermal growth factor receptor	Homo sapiens		 2.8							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795747		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5134	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5134&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329240	8034771							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8214	CN1CCN(CC1)C(=O)c1[nH]c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)cc1C	InChI=1S/C24H23ClFN7O2/c1-13-9-15(29-20(13)24(35)33-7-5-32(2)6-8-33)10-16-19-21(27-12-28-22(19)31-23(16)34)30-14-3-4-18(26)17(25)11-14/h3-4,9-12,29H,5-8H2,1-2H3,(H2,27,28,30,31,34)	FHYFHSYZOSQOFM-UHFFFAOYSA-N	5135	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({4-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26m	Epidermal growth factor receptor	Homo sapiens		 210							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5135	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5135&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329241	8034772							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8215	CN1CCN(CC1)C(=O)c1c[nH]c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)c1C	InChI=1S/C24H23ClFN7O2/c1-13-16(24(35)33-7-5-32(2)6-8-33)11-27-19(13)10-15-20-21(28-12-29-22(20)31-23(15)34)30-14-3-4-18(26)17(25)9-14/h3-4,9-12,27H,5-8H2,1-2H3,(H2,28,29,30,31,34)	UYSSUZUSGKWSFS-UHFFFAOYSA-N	5136	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-methyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26n	Epidermal growth factor receptor	Homo sapiens		 410							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5136	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5136&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329242	8034773							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8216	CCN1CCN(CC1)C(=O)c1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)[nH]1	InChI=1S/C25H25ClFN7O2/c1-3-33-6-8-34(9-7-33)25(36)20-10-14(2)19(31-20)12-16-21-22(28-13-29-23(21)32-24(16)35)30-15-4-5-18(27)17(26)11-15/h4-5,10-13,31H,3,6-9H2,1-2H3,(H2,28,29,30,32,35)	IKPVHBRKTATKGA-UHFFFAOYSA-N	5137	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(4-ethylpiperazin-1-yl)carbonyl]-3-methyl-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26o	Epidermal growth factor receptor	Homo sapiens		 13							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5137	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5137&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329243	8034774							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8217	CCN(CC)CCNC(=O)c1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)[nH]1	InChI=1S/C25H27ClFN7O2/c1-4-34(5-2)9-8-28-25(36)20-10-14(3)19(32-20)12-16-21-22(29-13-30-23(21)33-24(16)35)31-15-6-7-18(27)17(26)11-15/h6-7,10-13,32H,4-5,8-9H2,1-3H3,(H,28,36)(H2,29,30,31,33,35)	SXQLWNOERMLQGM-UHFFFAOYSA-N	5138	5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-4-methyl-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26p	Epidermal growth factor receptor	Homo sapiens		 1.2							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5138	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5138&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329244	8034775							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8218	CC1CN(CC(C)N1)C(=O)c1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)[nH]1	InChI=1S/C25H25ClFN7O2/c1-12-6-20(25(36)34-9-13(2)30-14(3)10-34)32-19(12)8-16-21-22(28-11-29-23(21)33-24(16)35)31-15-4-5-18(27)17(26)7-15/h4-8,11,13-14,30,32H,9-10H2,1-3H3,(H2,28,29,31,33,35)	WVDAQTVGUQLXLW-UHFFFAOYSA-N	5139	(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(3,5-dimethylpiperazin-1-yl)carbonyl]-3-methyl-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26q	Epidermal growth factor receptor	Homo sapiens		 5.9							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5139	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5139&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329245	8034776							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8219	CCN(CC)CC(O)CNC(=O)c1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)[nH]1	InChI=1S/C26H29ClFN7O3/c1-4-35(5-2)12-16(36)11-29-26(38)21-8-14(3)20(33-21)10-17-22-23(30-13-31-24(22)34-25(17)37)32-15-6-7-19(28)18(27)9-15/h6-10,13,16,33,36H,4-5,11-12H2,1-3H3,(H,29,38)(H2,30,31,32,34,37)	CBPCSPAXUJCCML-UHFFFAOYSA-N	5140	5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[3-(diethylamino)-2-hydroxypropyl]-4-methyl-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26r	Epidermal growth factor receptor	Homo sapiens		 0.45							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5140	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5140&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329246	8034777							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8220	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3cccc(c3)C#C)c12)C(=O)NCCN1CCOCC1	InChI=1S/C27H27N7O3/c1-3-18-5-4-6-19(14-18)31-24-23-20(26(35)33-25(23)30-16-29-24)15-21-17(2)13-22(32-21)27(36)28-7-8-34-9-11-37-12-10-34/h1,4-6,13-16,32H,7-12H2,2H3,(H,28,36)(H2,29,30,31,33,35)	ZJXFDKWJAGZFLT-UHFFFAOYSA-N	5141	5-{[(5Z)-4-[(3-ethynylphenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26s	Epidermal growth factor receptor	Homo sapiens		 18							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5141	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5141&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10300451	8034778							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8221	CCN(CC)CCNC(=O)c1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(Cl)cc4F)c23)[nH]1	InChI=1S/C25H27ClFN7O2/c1-4-34(5-2)9-8-28-25(36)20-10-14(3)19(31-20)12-16-21-22(29-13-30-23(21)33-24(16)35)32-18-7-6-15(26)11-17(18)27/h6-7,10-13,31H,4-5,8-9H2,1-3H3,(H,28,36)(H2,29,30,32,33,35)	VYCCLXYWLSXHKT-UHFFFAOYSA-N	5142	5-{[(5Z)-4-[(4-chloro-2-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-4-methyl-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26t	Epidermal growth factor receptor	Homo sapiens		 450							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5142	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5142&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329248	8034779							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8222	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc4CCCc4c3)c12)C(=O)N1CCOCC1	InChI=1S/C26H26N6O3/c1-15-11-21(26(34)32-7-9-35-10-8-32)30-20(15)13-19-22-23(27-14-28-24(22)31-25(19)33)29-18-6-5-16-3-2-4-17(16)12-18/h5-6,11-14,30H,2-4,7-10H2,1H3,(H2,27,28,29,31,33)	OZSZUGKQFYJEMK-UHFFFAOYSA-N	5143	(5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 28a	Epidermal growth factor receptor	Homo sapiens		 1410							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5143	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5143&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329249	8034780							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8223	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc4n(Cc5ccccc5)ccc4c3)c12)C(=O)N1CCOCC1	InChI=1S/C32H29N7O3/c1-20-15-26(32(41)38-11-13-42-14-12-38)36-25(20)17-24-28-29(33-19-34-30(28)37-31(24)40)35-23-7-8-27-22(16-23)9-10-39(27)18-21-5-3-2-4-6-21/h2-10,15-17,19,36H,11-14,18H2,1H3,(H2,33,34,35,37,40)	CBRVEUABHHKTIL-UHFFFAOYSA-N	5144	(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 28b	Epidermal growth factor receptor	Homo sapiens		 4.5							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5144	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5144&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329250	8034781							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8224	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)N1CCOCC1	InChI=1S/C31H28N8O3/c1-19-13-25(31(41)38-9-11-42-12-10-38)36-24(19)15-23-27-28(32-18-33-29(27)37-30(23)40)35-22-7-8-26-21(14-22)16-34-39(26)17-20-5-3-2-4-6-20/h2-8,13-16,18,36H,9-12,17H2,1H3,(H2,32,33,35,37,40)	MDCWIVYFXQKDOP-UHFFFAOYSA-N	5145	(5Z)-4-[(1-benzyl-1H-indazol-5-yl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 28c	Epidermal growth factor receptor	Homo sapiens		 1.8							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5145	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5145&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329251	8034782							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8225	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc4n(Cc5ccccc5)ccc4c3)c12)C(=O)NCCN1CCOCC1	InChI=1S/C34H34N8O3/c1-22-17-28(34(44)35-10-12-41-13-15-45-16-14-41)39-27(22)19-26-30-31(36-21-37-32(30)40-33(26)43)38-25-7-8-29-24(18-25)9-11-42(29)20-23-5-3-2-4-6-23/h2-9,11,17-19,21,39H,10,12-16,20H2,1H3,(H,35,44)(H2,36,37,38,40,43)	JHZHWAOFJSCIEJ-UHFFFAOYSA-N	5146	5-{[(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 28d	Epidermal growth factor receptor	Homo sapiens		 1.1							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5146	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5146&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329252	8034783							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8226	Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(N3CCCCC3)c12)C(=O)N1CCOCC1	InChI=1S/C22H26N6O3/c1-14-11-17(22(30)28-7-9-31-10-8-28)25-16(14)12-15-18-19(26-21(15)29)23-13-24-20(18)27-5-3-2-4-6-27/h11-13,25H,2-10H2,1H3,(H,23,24,26,29)	VIJTXHKQZRDGPG-UHFFFAOYSA-N	5147	(5Z)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-4-(piperidin-1-yl)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 29	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1016/s0960-894x(02)00364-5	10.7270/Q200009N	12127526	aid1795746		Sun, L; Cui, J; Liang, C; Zhou, Y; Nematalla, A; Wang, X; Chen, H; Tang, C; Wei, J	8/19/2002	7/18/2005	Sugen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5147&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329253	8034784							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8252	Oc1cc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2cc(O)c(O)c(Br)c2)\C#N)cc(Br)c1O	InChI=1S/C23H18Br2N4O6/c24-16-6-12(8-18(30)20(16)32)4-14(10-26)22(34)28-2-1-3-29-23(35)15(11-27)5-13-7-17(25)21(33)19(31)9-13/h4-9,30-33H,1-3H2,(H,28,34)(H,29,35)	XYZWEMNNBFBAKA-UHFFFAOYSA-N	5148	(2E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-{3-[(2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-cyanoprop-2-enamido]propyl}-2-cyanoprop-2-enamide::Dimeric Tyrphostin 1	Epidermal growth factor receptor	Homo sapiens		 340					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5148	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5148&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329254	8034785							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8253	Oc1ccc(\C=C(/C#N)C(=O)NCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C23H20N4O6/c24-12-16(8-14-2-4-18(28)20(30)10-14)22(32)26-6-1-7-27-23(33)17(13-25)9-15-3-5-19(29)21(31)11-15/h2-5,8-11,28-31H,1,6-7H2,(H,26,32)(H,27,33)	ZHOKHSGWBNPFQU-UHFFFAOYSA-N	5149	CHEMBL67535::(2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]propyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 2	Epidermal growth factor receptor	Homo sapiens		 400					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5149	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5149&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329255	8034786		CHEMBL67535					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8254	Oc1ccc(\C=C(/C#N)C(=O)NCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C22H18N4O6/c23-11-15(7-13-1-3-17(27)19(29)9-13)21(31)25-5-6-26-22(32)16(12-24)8-14-2-4-18(28)20(30)10-14/h1-4,7-10,27-30H,5-6H2,(H,25,31)(H,26,32)	PZIRTMUUDNWDHP-UHFFFAOYSA-N	5150	CHEMBL144908::(2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]ethyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 3	Epidermal growth factor receptor	Homo sapiens		 500					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5150	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5150&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329256	8034787		CHEMBL144908					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8255	Oc1ccc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C24H22N4O6/c25-13-17(9-15-3-5-19(29)21(31)11-15)23(33)27-7-1-2-8-28-24(34)18(14-26)10-16-4-6-20(30)22(32)12-16/h3-6,9-12,29-32H,1-2,7-8H2,(H,27,33)(H,28,34)	XHDRIPWTMPMRTA-UHFFFAOYSA-N	5151	(2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]butyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::CHEMBL144589::Dimeric Tyrphostin 4	Epidermal growth factor receptor	Homo sapiens		 600					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5151	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5151&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329257	8034788		CHEMBL144589					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8256	Oc1cc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O	InChI=1S/C24H22N4O8/c25-11-15(5-13-7-17(29)21(33)18(30)8-13)23(35)27-3-1-2-4-28-24(36)16(12-26)6-14-9-19(31)22(34)20(32)10-14/h5-10,29-34H,1-4H2,(H,27,35)(H,28,36)	ZJGWOFFIHTYMCZ-UHFFFAOYSA-N	5152	(2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydroxyphenyl)prop-2-enamido]butyl}-3-(3,4,5-trihydroxyphenyl)prop-2-enamide::CHEMBL358746::Dimeric Tyrphostin 5	Epidermal growth factor receptor	Homo sapiens		 600					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5152	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5152&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329258	8034789		CHEMBL358746					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8257	Oc1ccc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C25H24N4O6/c26-14-18(10-16-4-6-20(30)22(32)12-16)24(34)28-8-2-1-3-9-29-25(35)19(15-27)11-17-5-7-21(31)23(33)13-17/h4-7,10-13,30-33H,1-3,8-9H2,(H,28,34)(H,29,35)	KVIXQTKOWBEGMT-UHFFFAOYSA-N	5153	CHEMBL144842::(2E)-2-cyano-N-{5-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]pentyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 6	Epidermal growth factor receptor	Homo sapiens		 700					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5153	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5153&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329259	8034790		CHEMBL144842					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8258	Oc1ccc(\C=C(/C#N)C(=O)NCCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C26H26N4O6/c27-15-19(11-17-5-7-21(31)23(33)13-17)25(35)29-9-3-1-2-4-10-30-26(36)20(16-28)12-18-6-8-22(32)24(34)14-18/h5-8,11-14,31-34H,1-4,9-10H2,(H,29,35)(H,30,36)	WDXFBHIKHUGEOU-UHFFFAOYSA-N	5154	(2E)-2-cyano-N-{6-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]hexyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::CHEMBL144760::Dimeric Tyrphostin 7	Epidermal growth factor receptor	Homo sapiens		 700					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5154	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5154&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329260	8034791		CHEMBL144760					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8259	Oc1ccc(\C=C(/C#N)C(=O)NCCCCCCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C30H34N4O6/c31-19-23(15-21-9-11-25(35)27(37)17-21)29(39)33-13-7-5-3-1-2-4-6-8-14-34-30(40)24(20-32)16-22-10-12-26(36)28(38)18-22/h9-12,15-18,35-38H,1-8,13-14H2,(H,33,39)(H,34,40)	UXBLTQHRJBAYNB-UHFFFAOYSA-N	5155	(2E)-2-cyano-N-{10-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]decyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 8	Epidermal growth factor receptor	Homo sapiens		 1300					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5155	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5155&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329261	8034792							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8260	Oc1ccc(\C=C(/C#N)C(=O)NCc2cccc(CNC(=O)C(=C\c3ccc(O)c(O)c3)\C#N)c2)cc1O	InChI=1S/C28H22N4O6/c29-13-21(9-17-4-6-23(33)25(35)11-17)27(37)31-15-19-2-1-3-20(8-19)16-32-28(38)22(14-30)10-18-5-7-24(34)26(36)12-18/h1-12,33-36H,15-16H2,(H,31,37)(H,32,38)	GMDJBNDWRYPPBA-UHFFFAOYSA-N	5156	(2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]methyl}phenyl)methyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide::CHEMBL144159::Dimeric Tyrphostin 9	Epidermal growth factor receptor	Homo sapiens		 1600					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5156	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5156&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329262	8034793		CHEMBL144159					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8261	Oc1ccc(\C=C(/C#N)C(=O)NCC2CCCC(CNC(=O)C(=C\c3ccc(O)c(O)c3)\C#N)C2)cc1O	InChI=1S/C28H28N4O6/c29-13-21(9-17-4-6-23(33)25(35)11-17)27(37)31-15-19-2-1-3-20(8-19)16-32-28(38)22(14-30)10-18-5-7-24(34)26(36)12-18/h4-7,9-12,19-20,33-36H,1-3,8,15-16H2,(H,31,37)(H,32,38)	YESNFWRNMLAXJB-UHFFFAOYSA-N	5157	(2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]methyl}cyclohexyl)methyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 10	Epidermal growth factor receptor	Homo sapiens		 1800					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5157	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5157&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329263	8034794							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8262	COc1cc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2cc(OC)c(O)c(c2)[N+]([O-])=O)\C#N)cc(c1O)[N+]([O-])=O	InChI=1S/C26H24N6O10/c1-41-21-11-15(9-19(23(21)33)31(37)38)7-17(13-27)25(35)29-5-3-4-6-30-26(36)18(14-28)8-16-10-20(32(39)40)24(34)22(12-16)42-2/h7-12,33-34H,3-6H2,1-2H3,(H,29,35)(H,30,36)	KELGROZXKWYKRA-UHFFFAOYSA-N	5158	(2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(4-hydroxy-3-methoxy-5-nitrophenyl)prop-2-enamido]butyl}-3-(4-hydroxy-3-methoxy-5-nitrophenyl)prop-2-enamide::Dimeric Tyrphostin 11	Epidermal growth factor receptor	Homo sapiens		 112000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5158	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5158&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329264	8034795							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8263	Oc1ccc(\C=C(/C#N)C(=O)NC2CCCCC2NC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C26H24N4O6/c27-13-17(9-15-5-7-21(31)23(33)11-15)25(35)29-19-3-1-2-4-20(19)30-26(36)18(14-28)10-16-6-8-22(32)24(34)12-16/h5-12,19-20,31-34H,1-4H2,(H,29,35)(H,30,36)	LLQAFRKQJAOAMO-UHFFFAOYSA-N	5159	(2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]cyclohexyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 12	Epidermal growth factor receptor	Homo sapiens		 2100					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5159	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5159&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329265	8034796							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8264	Oc1ccc(\C=C(/C#N)C(=O)NCCCCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C28H30N4O6/c29-17-21(13-19-7-9-23(33)25(35)15-19)27(37)31-11-5-3-1-2-4-6-12-32-28(38)22(18-30)14-20-8-10-24(34)26(36)16-20/h7-10,13-16,33-36H,1-6,11-12H2,(H,31,37)(H,32,38)	LTAJUBMRIAMNSU-UHFFFAOYSA-N	5160	(2E)-2-cyano-N-{8-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]octyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 13	Epidermal growth factor receptor	Homo sapiens		 2200					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5160	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5160&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329266	8034797							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8265	Oc1ccc(\C=C(/C#N)C(=O)NCCN2CCN(CC2)C(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C26H25N5O6/c27-15-19(11-17-1-3-21(32)23(34)13-17)25(36)29-5-6-30-7-9-31(10-8-30)26(37)20(16-28)12-18-2-4-22(33)24(35)14-18/h1-4,11-14,32-35H,5-10H2,(H,29,36)	VUEAWOKXEQLRJW-UHFFFAOYSA-N	5161	(2E)-2-cyano-N-(2-{4-[(2E)-2-cyano-2-[(3,4-dihydroxyphenyl)methylidene]acetyl]piperazin-1-yl}ethyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 14	Epidermal growth factor receptor	Homo sapiens		 2200					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5161	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5161&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329267	8034798							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8266	Oc1ccc(\C=C(/C#N)C(=O)N2CCN(CC2)C(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C24H20N4O6/c25-13-17(9-15-1-3-19(29)21(31)11-15)23(33)27-5-7-28(8-6-27)24(34)18(14-26)10-16-2-4-20(30)22(32)12-16/h1-4,9-12,29-32H,5-8H2	LGNJLNMJHWXSGQ-UHFFFAOYSA-N	5162	CHEMBL358494::(2E)-2-({4-[(2E)-2-cyano-2-[(3,4-dihydroxyphenyl)methylidene]acetyl]piperazin-1-yl}carbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Dimeric Tyrphostin 15	Epidermal growth factor receptor	Homo sapiens		 4000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5162	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5162&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329268	8034799		CHEMBL358494					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8267	O=C(NCCCNC(=O)C(=C\c1ccc2[nH]ccc2c1)\C#N)C(=C\c1ccc2[nH]ccc2c1)\C#N	InChI=1S/C27H22N6O2/c28-16-22(14-18-2-4-24-20(12-18)6-10-30-24)26(34)32-8-1-9-33-27(35)23(17-29)15-19-3-5-25-21(13-19)7-11-31-25/h2-7,10-15,30-31H,1,8-9H2,(H,32,34)(H,33,35)	OBKFTXZDEKYDTC-UHFFFAOYSA-N	5163	(2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(1H-indol-5-yl)prop-2-enamido]propyl}-3-(1H-indol-5-yl)prop-2-enamide::Dimeric Tyrphostin 21	Epidermal growth factor receptor	Homo sapiens		>100000					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5163	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5163&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329269	8034800							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8268	Oc1ccc(\C=C(/C#N)S(=O)(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O	InChI=1S/C18H12N2O6S/c19-9-13(5-11-1-3-15(21)17(23)7-11)27(25,26)14(10-20)6-12-2-4-16(22)18(24)8-12/h1-8,21-24H	JMRYQFOYVAUPPK-UHFFFAOYSA-N	5164	(2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxyphenyl)eth-1-ene-1-]sulfonyl}-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Dimeric Tyrphostin 22	Epidermal growth factor receptor	Homo sapiens		 380					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5164	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5164&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329270	8034801							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8269	Oc1cc(\C=C(/C#N)S(=O)(=O)C(=C\c2cc(O)c(O)c(Br)c2)\C#N)cc(Br)c1O	InChI=1S/C18H10Br2N2O6S/c19-13-3-9(5-15(23)17(13)25)1-11(7-21)29(27,28)12(8-22)2-10-4-14(20)18(26)16(24)6-10/h1-6,23-26H	VBOBOVYYRHVGSJ-UHFFFAOYSA-N	5165	(2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-{[(1E)-2-(3-bromo-4,5-dihydroxyphenyl)-1-cyanoeth-1-ene-1-]sulfonyl}prop-2-enenitrile::Dimeric Tyrphostin 23	Epidermal growth factor receptor	Homo sapiens		 850					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5165	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5165&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329271	8034802							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8270	COc1cc(\C=C(/C#N)S(=O)(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O	InChI=1S/C20H16N2O8S/c1-29-17-7-11(5-15(23)19(17)25)3-13(9-21)31(27,28)14(10-22)4-12-6-16(24)20(26)18(8-12)30-2/h3-8,23-26H,1-2H3	RALUAQCUICRVFY-UHFFFAOYSA-N	5166	(2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxy-5-methoxyphenyl)eth-1-ene-1-]sulfonyl}-3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enenitrile::Dimeric Tyrphostin 24	Epidermal growth factor receptor	Homo sapiens		 940					7.6000	22.00 C	Curated from the literature by BindingDB	10.1021/jm960225d	10.7270/Q2V69GSZ	8960549	aid1795752		Gazit, A; Osherov, N; Gilon, C; Levitzki, A	12/6/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5166	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5166&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329272	8034803							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8271	Oc1ccc(\C=C(/C#N)C(=O)Nc2ccccc2)cc1O	InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)	HKHOVJYOELRGMV-UHFFFAOYSA-N	4304	cid_5328771::CHEMBL56731::(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide::tyrphostin 1	Epidermal growth factor receptor	Homo sapiens		 10000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4304	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4304&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328771	8033981		CHEMBL56731					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8272	N=C(C(C#N)C#N)C(=Cc1ccc2[nH]ccc2c1)C#N |w:8.8|	InChI=1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,13,19-20H	PEBPSCWSXYPIJD-UHFFFAOYSA-N	4277	(3Z)-2-amino-3-(1H-indol-5-ylmethylidene)prop-1-ene-1,1,3-tricarbonitrile::Indole-Containing Inhibitor 2::Tyrphostin deriv. 7	Epidermal growth factor receptor	Homo sapiens		 100000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4277	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4277&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895606	8033954							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8273	CC(NC(=O)C(=C\c1ccc2[nH]ccc2c1)\C#N)c1ccccc1	InChI=1S/C20H17N3O/c1-14(16-5-3-2-4-6-16)23-20(24)18(13-21)12-15-7-8-19-17(11-15)9-10-22-19/h2-12,14,22H,1H3,(H,23,24)	YAKSTXXJGSXXCJ-UHFFFAOYSA-N	5169	(2E)-2-cyano-3-(1H-indol-5-yl)-N-(1-phenylethyl)prop-2-enamide::Indole-Containing Inhibitor 3	Epidermal growth factor receptor	Homo sapiens		 10000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5169	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5169&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329273	8034804							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8274	Oc1ccc(cc1O)C(=O)C(=C\c1ccc2[nH]ccc2c1)\C#N	InChI=1S/C18H12N2O3/c19-10-14(18(23)13-2-4-16(21)17(22)9-13)8-11-1-3-15-12(7-11)5-6-20-15/h1-9,20-22H	TWEQSBKXFOZXRA-UHFFFAOYSA-N	5170	(2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol-5-yl)prop-2-enenitrile::Indole-Containing Inhibitor 4	Epidermal growth factor receptor	Homo sapiens		 10000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5170	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5170&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329274	8034805							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8275	Oc1ccc(cc1O)C(=O)C(=C\c1c[nH]c2ccccc12)\C#N	InChI=1S/C18H12N2O3/c19-9-12(18(23)11-5-6-16(21)17(22)8-11)7-13-10-20-15-4-2-1-3-14(13)15/h1-8,10,20-22H	TTZDOBVWBQXGDC-UHFFFAOYSA-N	5171	(2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol-3-yl)prop-2-enenitrile::Indole-Containing Inhibitor 5	Epidermal growth factor receptor	Homo sapiens		 30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5171	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5171&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329275	8034806							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8276	N#CC(=Cc1c[nH]c2ccccc12)C#N |(2.53,2.99,;1.76,4.33,;.99,5.66,;-.55,5.66,;-1.64,4.57,;-.73,3.32,;-1.64,2.08,;-3.1,2.55,;-4.32,1.78,;-5.65,2.55,;-5.65,4.1,;-4.32,4.87,;-3.1,4.1,;1.76,6.99,;2.53,8.33,)|	InChI=1S/C12H7N3/c13-6-9(7-14)5-10-8-15-12-4-2-1-3-11(10)12/h1-5,8,15H	KCGMQWDGOQQAGN-UHFFFAOYSA-N	5172	2-(1H-indol-3-ylmethylidene)propanedinitrile::Indole-Containing Inhibitor 6	Epidermal growth factor receptor	Homo sapiens		>100000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5172	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5172&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			269623	8034807							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8277	NC(=S)C(=C\c1c[nH]c2ccccc12)\C#N	InChI=1S/C12H9N3S/c13-6-8(12(14)16)5-9-7-15-11-4-2-1-3-10(9)11/h1-5,7,15H,(H2,14,16)	YGJSREKVWCOLRY-UHFFFAOYSA-N	5173	(2E)-2-cyano-3-(1H-indol-3-yl)prop-2-enethioamide::Indole-Containing Inhibitor 7	Epidermal growth factor receptor	Homo sapiens		 65000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5173	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5173&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2302598	8034808							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8278	N=C(C(C#N)C#N)C(=Cc1c[nH]c2ccccc12)C#N |w:8.8|	InChI=1S/C15H9N5/c16-6-10(15(19)12(7-17)8-18)5-11-9-20-14-4-2-1-3-13(11)14/h1-5,9,12,19-20H	DMLMRVXYGWEZFP-UHFFFAOYSA-N	5174	(3Z)-2-amino-3-(1H-indol-3-ylmethylidene)prop-1-ene-1,1,3-tricarbonitrile::Indole-Containing Inhibitor 8	Epidermal growth factor receptor	Homo sapiens		>300000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5174	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5174&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91895614	8034809							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8279	O=C(\C(=C\c1c[nH]c2ccccc12)C#N)c1ccccc1	InChI=1S/C18H12N2O/c19-11-14(18(21)13-6-2-1-3-7-13)10-15-12-20-17-9-5-4-8-16(15)17/h1-10,12,20H	SBVGJXFYLSNMAI-UHFFFAOYSA-N	5175	(2E)-2-benzoyl-3-(1H-indol-3-yl)prop-2-enenitrile::Indole-Containing Inhibitor 9	Epidermal growth factor receptor	Homo sapiens		 300000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5175	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5175&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329276	8034810							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8280	NC(=O)C(=C\c1c[nH]c2ccccc12)\C#N	InChI=1S/C12H9N3O/c13-6-8(12(14)16)5-9-7-15-11-4-2-1-3-10(9)11/h1-5,7,15H,(H2,14,16)	NLJUQIIPXVMEAA-UHFFFAOYSA-N	5176	(2E)-2-cyano-3-(1H-indol-3-yl)prop-2-enamide::Indole-Containing Inhibitor 10	Epidermal growth factor receptor	Homo sapiens		 65000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5176	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5176&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			1551085	8034811							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8281	Nc1[nH]nc(C(=Cc2c[nH]c3ccccc23)C#N)c1C#N |w:6.6|	InChI=1S/C15H10N6/c16-6-9(14-12(7-17)15(18)21-20-14)5-10-8-19-13-4-2-1-3-11(10)13/h1-5,8,19H,(H3,18,20,21)	OJMXHLJIMZMFGX-UHFFFAOYSA-N	5177	3-amino-5-[(1Z)-1-cyano-2-(1H-indol-3-yl)eth-1-en-1-yl]-1H-pyrazole-4-carbonitrile::Indole-Containing Inhibitor 11	Epidermal growth factor receptor	Homo sapiens		 100000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5177	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5177&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329277	8034812							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8282	N#C\C(=C/c1c[nH]c2ccccc12)c1nc2ccccc2s1	InChI=1S/C18H11N3S/c19-10-12(18-21-16-7-3-4-8-17(16)22-18)9-13-11-20-15-6-2-1-5-14(13)15/h1-9,11,20H	KKZSLQGVLBCOIH-UHFFFAOYSA-N	5178	(2E)-2-(1,3-benzothiazol-2-yl)-3-(1H-indol-3-yl)prop-2-enenitrile::Indole-Containing Inhibitor 12	Epidermal growth factor receptor	Homo sapiens		 100000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5178	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5178&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329278	8034813							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8283	COc1ccc2nc(Cl)c(cc2c1)-c1ccccc1	InChI=1S/C16H12ClNO/c1-19-13-7-8-15-12(9-13)10-14(16(17)18-15)11-5-3-2-4-6-11/h2-10H,1H3	GGBHOBDCDNXFFD-UHFFFAOYSA-N	5179	2-chloro-6-methoxy-3-phenylquinoline::Quinoline-Containing Inhibitor 13	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5179	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5179&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329279	8034814							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8284	Clc1nc2cc3OCOc3cc2cc1-c1ccccc1	InChI=1S/C16H10ClNO2/c17-16-12(10-4-2-1-3-5-10)6-11-7-14-15(20-9-19-14)8-13(11)18-16/h1-8H,9H2	TWSDEOXKXYWQFW-UHFFFAOYSA-N	5180	6-chloro-7-phenyl-2H-[1,3]dioxolo[4,5-g]quinoline::Quinoline-Containing Inhibitor 14	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5180	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5180&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329280	8034815							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8285	COc1cc2nc(Cl)c(cc2c(OC)c1OC)-c1ccccc1	InChI=1S/C18H16ClNO3/c1-21-15-10-14-13(16(22-2)17(15)23-3)9-12(18(19)20-14)11-7-5-4-6-8-11/h4-10H,1-3H3	GHKHNSLJHMVOEJ-UHFFFAOYSA-N	5181	2-chloro-5,6,7-trimethoxy-3-phenylquinoline::Quinoline-Containing Inhibitor 15	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5181	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5181&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329281	8034816							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8286	COc1ccc(OC)c2nc(Cl)c(cc12)-c1ccccc1	InChI=1S/C17H14ClNO2/c1-20-14-8-9-15(21-2)16-13(14)10-12(17(18)19-16)11-6-4-3-5-7-11/h3-10H,1-2H3	YWNHDGBMSPPQJA-UHFFFAOYSA-N	5182	2-chloro-5,8-dimethoxy-3-phenylquinoline::Quinoline-Containing Inhibitor 16	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5182	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5182&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329282	8034817							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8287	COc1cc2cc(c(Cl)nc2cc1OC)-c1ccccc1	InChI=1S/C17H14ClNO2/c1-20-15-9-12-8-13(11-6-4-3-5-7-11)17(18)19-14(12)10-16(15)21-2/h3-10H,1-2H3	JOYQLLBQXFUCSK-UHFFFAOYSA-N	5183	2-chloro-6,7-dimethoxy-3-phenylquinoline::2-Chloro-3-phenyl-6,7-dimethoxyquinoline::Quinoline-Containing Inhibitor 17	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5183	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5183&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			2794462	8034818							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8288	COc1cc2cc(-c3ccccc3)c(nc2cc1OC)-c1ccccc1	InChI=1S/C23H19NO2/c1-25-21-14-18-13-19(16-9-5-3-6-10-16)23(17-11-7-4-8-12-17)24-20(18)15-22(21)26-2/h3-15H,1-2H3	MRAWBMVCIHFKSI-UHFFFAOYSA-N	5184	6,7-dimethoxy-2,3-diphenylquinoline::2,3-Diphenyl-6,7-dimethoxyquinoline::Quinoline-Containing Inhibitor 18	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5184	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5184&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329283	8034819							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8289	COC(=O)c1cc2cc(OC)c(OC)cc2nc1-c1ccc(cc1)[N+]([O-])=O	InChI=1S/C19H16N2O6/c1-25-16-9-12-8-14(19(22)27-3)18(20-15(12)10-17(16)26-2)11-4-6-13(7-5-11)21(23)24/h4-10H,1-3H3	ZHROVCLRKOLMGN-UHFFFAOYSA-N	5185	(2-(p-Nitrophenyl)-3-carbomethoxy-6,7-dimethoxyquinoline)::methyl 6,7-dimethoxy-2-(4-nitrophenyl)quinoline-3-carboxylate::Quinoline-Containing Inhibitor 19	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5185	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5185&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329284	8034820							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8290	O=C(Cc1ccccc1)Nc1cnc2ccccc2c1	InChI=1S/C17H14N2O/c20-17(10-13-6-2-1-3-7-13)19-15-11-14-8-4-5-9-16(14)18-12-15/h1-9,11-12H,10H2,(H,19,20)	HVAOGEIUKHSAGM-UHFFFAOYSA-N	5186	2-phenyl-N-(quinolin-3-yl)acetamide::Quinoline-Containing Inhibitor 20	Epidermal growth factor receptor	Homo sapiens		>30000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5186	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5186&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329285	8034821							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8291	N#C\[#6](=[#6]\c1ccnc2ccccc12)C#N	InChI=1S/C13H6N3/c14-8-10(9-15)7-11-5-6-16-13-4-2-1-3-12(11)13/h1-6H	YCTIYOFAIBUURJ-UHFFFAOYSA-N	5187	4-Quinylidenemalononitrile::2-(quinolin-4-ylmethylidene)propanedinitrile::Quinoline-Containing Inhibitor 21	Epidermal growth factor receptor	Homo sapiens		 10000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5187	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5187&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			297036	8034822							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8292	N#C\[#6](=[#6]\c1cccc2ccccc12)C#N	InChI=1S/C14H7N2/c15-9-11(10-16)8-13-6-3-5-12-4-1-2-7-14(12)13/h1-7H	MKBJXHKFIGVWDE-UHFFFAOYSA-N	5188	2-(naphthalen-1-ylmethylidene)propanedinitrile::naphthalene deriv. 22	Epidermal growth factor receptor	Homo sapiens		>100000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5188	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5188&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			18092	8034823							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8293	NC(=O)C(=C\c1cccc2ccccc12)\C#N	InChI=1S/C14H10N2O/c15-9-12(14(16)17)8-11-6-3-5-10-4-1-2-7-13(10)11/h1-8H,(H2,16,17)	AVMHTBJNERNMNF-UHFFFAOYSA-N	5189	(2E)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide::naphthalene deriv. 23	Epidermal growth factor receptor	Homo sapiens		>100000					7.5000	4.00 C	Curated from the literature by BindingDB	10.1021/jm950727b	10.7270/Q2QF8R2N	8667360	aid1795753		Gazit, A; App, H; McMahon, G; Chen, J; Levitzki, A; Bohmer, FD	5/24/1996	7/19/2005	Hebrew University of Jerusalem	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5189	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5189&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			730856	8034824							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8638	CS(=O)(=O)CCNCc1nc(cs1)-c1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1	InChI=1S/C21H19ClFN5O2S2/c1-32(29,30)7-6-24-10-20-28-19(11-31-20)13-2-5-18-15(8-13)21(26-12-25-18)27-14-3-4-17(23)16(22)9-14/h2-5,8-9,11-12,24H,6-7,10H2,1H3,(H,25,26,27)	BNEUQUONQBLCSG-UHFFFAOYSA-N	5439	N-(3-chloro-4-fluorophenyl)-6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)quinazolin-4-amine::6-Thiazolylquinazoline 1	Epidermal growth factor receptor	Homo sapiens		 35					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5439&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329475	8035058							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8639	CS(=O)(=O)CCNCc1nc(cs1)-c1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1	InChI=1S/C28H27N5O3S2/c1-38(34,35)14-13-29-16-27-33-26(18-37-27)21-7-12-25-24(15-21)28(31-19-30-25)32-22-8-10-23(11-9-22)36-17-20-5-3-2-4-6-20/h2-12,15,18-19,29H,13-14,16-17H2,1H3,(H,30,31,32)	GSPYOWLUBSMHCV-UHFFFAOYSA-N	5440	N-[4-(benzyloxy)phenyl]-6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)quinazolin-4-amine::6-Thiazolylquinazoline 2	Epidermal growth factor receptor	Homo sapiens		 82					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5440&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329476	8035059							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8640	CS(=O)(=O)CCNCc1nc(cs1)-c1ccc2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1	InChI=1S/C29H27N7O2S2/c1-40(37,38)12-11-30-16-28-35-26(18-39-28)21-7-9-25-24(14-21)29(32-19-31-25)34-23-8-10-27-22(13-23)15-33-36(27)17-20-5-3-2-4-6-20/h2-10,13-15,18-19,30H,11-12,16-17H2,1H3,(H,31,32,34)	ZJAASMJOPRABKY-UHFFFAOYSA-N	5441	N-(1-benzyl-1H-indazol-5-yl)-6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)quinazolin-4-amine::6-Thiazolylquinazoline 3	Epidermal growth factor receptor	Homo sapiens		 71					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329477	8035060							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8641	CS(=O)(=O)CCNCc1nc(cs1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(c4)C(F)(F)F)cc3)c2c1	InChI=1S/C29H26F3N5O3S2/c1-42(38,39)12-11-33-15-27-37-26(17-41-27)20-5-10-25-24(14-20)28(35-18-34-25)36-22-6-8-23(9-7-22)40-16-19-3-2-4-21(13-19)29(30,31)32/h2-10,13-14,17-18,33H,11-12,15-16H2,1H3,(H,34,35,36)	OOURSYCFPYHWPU-UHFFFAOYSA-N	5442	6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)-N-(4-{[3-(trifluoromethyl)phenyl]methoxy}phenyl)quinazolin-4-amine::6-Thiazolylquinazoline 4	Epidermal growth factor receptor	Homo sapiens		 540					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5442&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329478	8035061							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8642	CS(=O)(=O)CCNCc1nc(cs1)-c1ccc2ncnc(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2c1	InChI=1S/C28H26ClN5O3S2/c1-39(35,36)12-11-30-15-27-34-25(17-38-27)20-7-9-24-22(13-20)28(32-18-31-24)33-21-8-10-26(23(29)14-21)37-16-19-5-3-2-4-6-19/h2-10,13-14,17-18,30H,11-12,15-16H2,1H3,(H,31,32,33)	AXVKGZLOECWENV-UHFFFAOYSA-N	5443	N-[4-(benzyloxy)-3-chlorophenyl]-6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)quinazolin-4-amine::6-Thiazolylquinazoline 5	Epidermal growth factor receptor	Homo sapiens		 8					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329479	8035062							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8643	CS(=O)(=O)CCNCc1nc(cs1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C28H25ClFN5O3S2/c1-40(36,37)10-9-31-14-27-35-25(16-39-27)19-5-7-24-22(12-19)28(33-17-32-24)34-21-6-8-26(23(29)13-21)38-15-18-3-2-4-20(30)11-18/h2-8,11-13,16-17,31H,9-10,14-15H2,1H3,(H,32,33,34)	MNNXRVSQOABRRP-UHFFFAOYSA-N	5444	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)quinazolin-4-amine::CHEMBL453376::6-Thiazolylquinazoline 6	Epidermal growth factor receptor	Homo sapiens		 10					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329480	8035063		CHEMBL453376					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8644	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::cid_208908::CHEMBL554::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::LAPATINIB DITOSYLATE::GW572016::Tykerb::US9730934, Lapatinib ditosylate::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib	Epidermal growth factor receptor	Homo sapiens		 10					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			208908	8035064		CHEMBL554	DB01259				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8645	COCCOc1cc2c(cc1OCCOC)ncnc2Nc3cccc(c3)C#C	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	Erlotinib::OSI-774::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::CHEMBL553::ERLOTINIB HYDROCHLORIDE::cid_176870::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::Tarceva::US9409845, Table 1, Compound 22: erlotinib::US10189853, erlotinib::US9730934, Erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::WO2022090481, Example erlotinib	Epidermal growth factor receptor	Homo sapiens		 1					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065		CHEMBL553	DB00530				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8646	COc1cc2c(cc1OCCCN3CCOCC3)c(ncn2)Nc4ccc(c(c4)Cl)F	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	ZD1839::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::cid_123631::CHEMBL939::GEFITINIB::Iressa::US9416123, Gefitinib::US10106508, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::US10507209, Compound Gefitinib::WO2022090481, Example gefitinib	Epidermal growth factor receptor	Homo sapiens		 1					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2003.10.010	10.7270/Q2HQ3X4M	14684309	aid1795774		Zhang, YM; Cockerill, S; Guntrip, SB; Rusnak, D; Smith, K; Vanderwall, D; Wood, E; Lackey, K	1/5/2004	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	IRE	2ITZ,2ITY,2ITO,5Y7Z,4WKQ,4I22,5Y80,3UG2	123631	8035066		CHEMBL939	DB00317				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8656	Oc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1	InChI=1S/C21H17N3O2/c25-17-8-11-20-19(12-17)21(23-14-22-20)24-16-6-9-18(10-7-16)26-13-15-4-2-1-3-5-15/h1-12,14,25H,13H2,(H,22,23,24)	BURBAFXROHRDAV-UHFFFAOYSA-N	5448	4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-ol::4-anilinoquinazoline 4a	Epidermal growth factor receptor	Homo sapiens		 98					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329481	8035067							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8657	CS(=O)(=O)CCN(CCCCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1)C(=O)C(F)(F)F	InChI=1S/C30H31F3N4O5S/c1-43(39,40)18-16-37(29(38)30(31,32)33)15-5-6-17-41-25-13-14-27-26(19-25)28(35-21-34-27)36-23-9-11-24(12-10-23)42-20-22-7-3-2-4-8-22/h2-4,7-14,19,21H,5-6,15-18,20H2,1H3,(H,34,35,36)	XUAWYHMIPSETPV-UHFFFAOYSA-N	5449	N-{4-[(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-yl)oxy]butyl}-2,2,2-trifluoro-N-(2-methanesulfonylethyl)acetamide::6-alkoxy-4-anilinoquinazoline 7a	Epidermal growth factor receptor	Homo sapiens		 263					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329482	8035068							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8658	CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1	InChI=1S/C28H32N4O4S/c1-37(33,34)18-16-29-15-5-6-17-35-25-13-14-27-26(19-25)28(31-21-30-27)32-23-9-11-24(12-10-23)36-20-22-7-3-2-4-8-22/h2-4,7-14,19,21,29H,5-6,15-18,20H2,1H3,(H,30,31,32)	YNAWKCAJCGIVQB-UHFFFAOYSA-N	5450	N-[4-(benzyloxy)phenyl]-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 8a	Epidermal growth factor receptor	Homo sapiens		 74					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5450&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329483	8035069							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8659	COc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1	InChI=1S/C22H19N3O2/c1-26-19-11-12-21-20(13-19)22(24-15-23-21)25-17-7-9-18(10-8-17)27-14-16-5-3-2-4-6-16/h2-13,15H,14H2,1H3,(H,23,24,25)	RARTTYYZTRKYDS-UHFFFAOYSA-N	5451	N-[4-(benzyloxy)phenyl]-6-methoxyquinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 9a	Epidermal growth factor receptor	Homo sapiens		 68					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5451&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329484	8035070							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8660	C=CCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1	InChI=1S/C24H21N3O2/c1-2-14-28-21-12-13-23-22(15-21)24(26-17-25-23)27-19-8-10-20(11-9-19)29-16-18-6-4-3-5-7-18/h2-13,15,17H,1,14,16H2,(H,25,26,27)	PNZSTSKDYDRMIY-UHFFFAOYSA-N	5452	N-[4-(benzyloxy)phenyl]-6-(prop-2-en-1-yloxy)quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 10a	Epidermal growth factor receptor	Homo sapiens		 79					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5452&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329485	8035071							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8661	CS(=O)(=O)CCNCCCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1	InChI=1S/C27H30N4O4S/c1-36(32,33)17-15-28-14-5-16-34-24-12-13-26-25(18-24)27(30-20-29-26)31-22-8-10-23(11-9-22)35-19-21-6-3-2-4-7-21/h2-4,6-13,18,20,28H,5,14-17,19H2,1H3,(H,29,30,31)	PFBNCPMUCGZALP-UHFFFAOYSA-N	5453	N-[4-(benzyloxy)phenyl]-6-{3-[(2-methanesulfonylethyl)amino]propoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 12a	Epidermal growth factor receptor	Homo sapiens		 104					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5453&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329486	8035072							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8662	CN(CCCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1)CCS(C)(=O)=O	InChI=1S/C28H32N4O4S/c1-32(16-18-37(2,33)34)15-6-17-35-25-13-14-27-26(19-25)28(30-21-29-27)31-23-9-11-24(12-10-23)36-20-22-7-4-3-5-8-22/h3-5,7-14,19,21H,6,15-18,20H2,1-2H3,(H,29,30,31)	XOQKZEMXCAEBHU-UHFFFAOYSA-N	5454	N-[4-(benzyloxy)phenyl]-6-{3-[(2-methanesulfonylethyl)(methyl)amino]propoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 13a	Epidermal growth factor receptor	Homo sapiens		 830					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5454&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329487	8035073							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8663	FC(F)(F)C(=O)NCCCCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1	InChI=1S/C27H25F3N4O3/c28-27(29,30)26(35)31-14-4-5-15-36-22-12-13-24-23(16-22)25(33-18-32-24)34-20-8-10-21(11-9-20)37-17-19-6-2-1-3-7-19/h1-3,6-13,16,18H,4-5,14-15,17H2,(H,31,35)(H,32,33,34)	BVASVOATLGXWDS-UHFFFAOYSA-N	5455	N-{4-[(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-yl)oxy]butyl}-2,2,2-trifluoroacetamide::6-alkoxy-4-anilinoquinazoline 14a	Epidermal growth factor receptor	Homo sapiens		 74					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5455&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329488	8035074							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8664	CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3cccc(c3)C#C)c2c1	InChI=1S/C23H26N4O3S/c1-3-18-7-6-8-19(15-18)27-23-21-16-20(9-10-22(21)25-17-26-23)30-13-5-4-11-24-12-14-31(2,28)29/h1,6-10,15-17,24H,4-5,11-14H2,2H3,(H,25,26,27)	WLLKPDBSPXZCTG-UHFFFAOYSA-N	5456	N-(3-ethynylphenyl)-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 8b	Epidermal growth factor receptor	Homo sapiens		 11					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5456&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329489	8035075							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8665	CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1	InChI=1S/C21H24ClFN4O3S/c1-31(28,29)11-9-24-8-2-3-10-30-16-5-7-20-17(13-16)21(26-14-25-20)27-15-4-6-19(23)18(22)12-15/h4-7,12-14,24H,2-3,8-11H2,1H3,(H,25,26,27)	SPEQBPSZWOMRLO-UHFFFAOYSA-N	5457	N-(3-chloro-4-fluorophenyl)-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 8c	Epidermal growth factor receptor	Homo sapiens		 20					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5457&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329490	8035076							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8666	CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3ccc(cc3)S(=O)(=O)c3ccccc3)c2c1	InChI=1S/C27H30N4O5S2/c1-37(32,33)18-16-28-15-5-6-17-36-22-11-14-26-25(19-22)27(30-20-29-26)31-21-9-12-24(13-10-21)38(34,35)23-7-3-2-4-8-23/h2-4,7-14,19-20,28H,5-6,15-18H2,1H3,(H,29,30,31)	PEBATQNNPRRNAH-UHFFFAOYSA-N	5458	N-[4-(benzenesulfonyl)phenyl]-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 8d	Epidermal growth factor receptor	Homo sapiens		 93					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5458&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329491	8035077							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8667	CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C28H30ClFN4O4S/c1-39(35,36)14-12-31-11-2-3-13-37-23-8-9-26-24(17-23)28(33-19-32-26)34-22-7-10-27(25(29)16-22)38-18-20-5-4-6-21(30)15-20/h4-10,15-17,19,31H,2-3,11-14,18H2,1H3,(H,32,33,34)	FUAWEXVTNBAJGV-UHFFFAOYSA-N	5459	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 8e	Epidermal growth factor receptor	Homo sapiens		 27					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5459&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329492	8035078							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
8668	CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c2c1	InChI=1S/C29H31FN6O3S/c1-40(37,38)14-12-31-11-2-3-13-39-25-8-9-27-26(17-25)29(33-20-32-27)35-24-7-10-28-22(16-24)18-34-36(28)19-21-5-4-6-23(30)15-21/h4-10,15-18,20,31H,2-3,11-14,19H2,1H3,(H,32,33,35)	FMKJJNOFXVDHKH-UHFFFAOYSA-N	5460	N-{1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine::6-alkoxy-4-anilinoquinazoline 8f	Epidermal growth factor receptor	Homo sapiens		 24					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/s0960-894x(02)01047-8	10.7270/Q2D21VS2	12639547	aid1795775		Gaul, MD; Guo, Y; Affleck, K; Cockerill, GS; Gilmer, TM; Griffin, RJ; Guntrip, S; Keith, BR; Knight, WB; Mullin, RJ; Murray, DM; Rusnak, DW; Smith, K; Tadepalli, S; Wood, ER; Lackey, K	2/24/2003	8/11/2005	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5460&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5329493	8035079							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10602	OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1	InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	UCHQCSDTPQKAKL-UHFFFAOYSA-N	6416	3-[[5-[6-[(3-chlorophenyl)amino]pyrazinyl]-3-pyridinyl]amino]-1-propanol::Pyrazine-Pyridine deriv. 15::3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridin-3-yl)amino]propan-1-ol::Pyrazine-Pyridine Biheteroaryl 7	Epidermal growth factor receptor	Homo sapiens		 1360							Curated from the literature by BindingDB	10.1021/jm040099a	10.7270/Q2HM56NC	15771433	aid1795900		Kuo, GH; Wang, A; Emanuel, S; Deangelis, A; Zhang, R; Connolly, PJ; Murray, WV; Gruninger, RH; Sechler, J; Fuentes-Pesquera, A; Johnson, D; Middleton, SA; Jolliffe, L; Chen, X	3/24/2005	11/5/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330387	8036008							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10626	OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1	InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	UCHQCSDTPQKAKL-UHFFFAOYSA-N	6416	3-[[5-[6-[(3-chlorophenyl)amino]pyrazinyl]-3-pyridinyl]amino]-1-propanol::Pyrazine-Pyridine deriv. 15::3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridin-3-yl)amino]propan-1-ol::Pyrazine-Pyridine Biheteroaryl 7	Epidermal growth factor receptor	Homo sapiens		 1360							Curated from the literature by BindingDB	10.1021/jm058205b	10.7270/Q2NC5ZD5	16033269	aid1795895		Kuo, GH; Prouty, C; Wang, A; Emanuel, S; Deangelis, A; Zhang, Y; Song, F; Beall, L; Connolly, PJ; Karnachi, P; Chen, X; Gruninger, RH; Sechler, J; Fuentes-Pesquera, A; Middleton, SA; Jolliffe, L; Murray, WV	7/28/2005	11/7/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330387	8036008							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10627	OCCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1	InChI=1S/C19H20ClN5O/c20-15-4-3-5-16(9-15)24-19-13-22-12-18(25-19)14-8-17(11-21-10-14)23-6-1-2-7-26/h3-5,8-13,23,26H,1-2,6-7H2,(H,24,25)	IDNNHUIRPPFJBA-UHFFFAOYSA-N	6417	4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridin-3-yl)amino]butan-1-ol::4-{5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-pyridin-3-ylamino}-butan-1-ol::Pyrazine-Pyridine Biheteroaryl 39	Epidermal growth factor receptor	Homo sapiens		 7400							Curated from the literature by BindingDB	10.1021/jm058205b	10.7270/Q2NC5ZD5	16033269	aid1795895		Kuo, GH; Prouty, C; Wang, A; Emanuel, S; Deangelis, A; Zhang, Y; Song, F; Beall, L; Connolly, PJ; Karnachi, P; Chen, X; Gruninger, RH; Sechler, J; Fuentes-Pesquera, A; Middleton, SA; Jolliffe, L; Murray, WV	7/28/2005	11/7/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330388	8036009							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10628	CN(C)CCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1	InChI=1S/C19H21ClN6/c1-26(2)7-6-23-17-8-14(10-21-11-17)18-12-22-13-19(25-18)24-16-5-3-4-15(20)9-16/h3-5,8-13,23H,6-7H2,1-2H3,(H,24,25)	XTEWWTLBXKFYCF-UHFFFAOYSA-N	6418	N-{5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-pyridin-3-yl}-N ,N -dimethyl-ethane-1,2-diamine::N-(3-chlorophenyl)-6-(5-{[2-(dimethylamino)ethyl]amino}pyridin-3-yl)pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 41	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm058205b	10.7270/Q2NC5ZD5	16033269	aid1795895		Kuo, GH; Prouty, C; Wang, A; Emanuel, S; Deangelis, A; Zhang, Y; Song, F; Beall, L; Connolly, PJ; Karnachi, P; Chen, X; Gruninger, RH; Sechler, J; Fuentes-Pesquera, A; Middleton, SA; Jolliffe, L; Murray, WV	7/28/2005	11/7/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330389	8036010							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10629	Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3cccnc3)c2)c1	InChI=1S/C23H21ClN6/c24-19-6-1-7-20(11-19)29-23-16-27-15-22(30-23)18-10-21(14-26-13-18)28-9-3-5-17-4-2-8-25-12-17/h1-2,4,6-8,10-16,28H,3,5,9H2,(H,29,30)	IRNVMUQZQDLZAK-UHFFFAOYSA-N	6419	N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine::N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]amino]-3-pyridinyl]-2-pyrazinamine::Pyrazine-Pyridine Biheteroaryl 56	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm058205b	10.7270/Q2NC5ZD5	16033269	aid1795895		Kuo, GH; Prouty, C; Wang, A; Emanuel, S; Deangelis, A; Zhang, Y; Song, F; Beall, L; Connolly, PJ; Karnachi, P; Chen, X; Gruninger, RH; Sechler, J; Fuentes-Pesquera, A; Middleton, SA; Jolliffe, L; Murray, WV	7/28/2005	11/7/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330390	8036011							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10782	CN1c2c(cnc(n2)Nc3cccc(c3)CO)C=C(C1=O)c4c(cccc4Cl)Cl	InChI=1S/C21H16Cl2N4O2/c1-27-19-13(9-15(20(27)29)18-16(22)6-3-7-17(18)23)10-24-21(26-19)25-14-5-2-4-12(8-14)11-28/h2-10,28H,11H2,1H3,(H,24,25,26)	ZIQFYVPVJZEOFS-UHFFFAOYSA-N	3085	6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::PD166326	Epidermal growth factor receptor	Homo sapiens		 82							Curated from the literature by BindingDB	10.1016/s0006-2952(00)00405-6	10.7270/Q2MC8X7B	10974196			Kraker, AJ; Hartl, BG; Amar, AM; Barvian, MR; Showalter, HD; Moore, CW	10/1/2000	11/16/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3085	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	P16	2FO0,2G2H,1OPK,1OPL	447700	8032832			DB08339				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10783	Cn1c2nc(Nc3ccc(F)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(-.18,-.45,;-.18,1.09,;-1.51,1.86,;-2.84,1.08,;-4.18,1.85,;-5.51,1.08,;-6.84,1.86,;-6.84,3.4,;-8.18,4.17,;-9.51,3.4,;-10.84,4.17,;-9.51,1.86,;-8.18,1.08,;-4.18,3.39,;-2.84,4.16,;-1.51,3.4,;-.18,4.17,;1.16,3.4,;2.49,4.17,;2.49,5.71,;1.16,6.48,;3.83,6.48,;5.16,5.71,;5.16,4.17,;3.83,3.39,;3.83,1.85,;1.16,1.86,;2.49,1.09,)|	InChI=1S/C20H13Cl2FN4O/c1-27-18-11(9-14(19(27)28)17-15(21)3-2-4-16(17)22)10-24-20(26-18)25-13-7-5-12(23)6-8-13/h2-10H,1H3,(H,24,25,26)	ZSHRAUSJZQDIJR-UHFFFAOYSA-N	6569	6-(2,6-dichlorophenyl)-2-[(4-fluorophenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD173956	Epidermal growth factor receptor	Homo sapiens		 380							Curated from the literature by BindingDB	10.1016/s0006-2952(00)00405-6	10.7270/Q2MC8X7B	10974196			Kraker, AJ; Hartl, BG; Amar, AM; Barvian, MR; Showalter, HD; Moore, CW	10/1/2000	11/16/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6569&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330524	8036146							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10784	Cc1cc(ccc1F)Nc2ncc3c(n2)N(C(=O)C(=C3)c4c(cccc4Cl)Cl)C	InChI=1S/C21H15Cl2FN4O/c1-11-8-13(6-7-17(11)24)26-21-25-10-12-9-14(20(29)28(2)19(12)27-21)18-15(22)4-3-5-16(18)23/h3-10H,1-2H3,(H,25,26,27)	SLCFEJAMCRLYRG-UHFFFAOYSA-N	6572	6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one::PD-180970::6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD180970	Epidermal growth factor receptor	Homo sapiens		 390							Curated from the literature by BindingDB	10.1016/s0006-2952(00)00405-6	10.7270/Q2MC8X7B	10974196			Kraker, AJ; Hartl, BG; Amar, AM; Barvian, MR; Showalter, HD; Moore, CW	10/1/2000	11/16/2005	Parke-Davis Pharmaceutical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6572&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	JIN	2HZI	5311104	8036149							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
10836	O=C(Nc1ccccn1)Nc1cccc2C(=O)N3CCC[C@@H]3c12 |r|	InChI=1S/C17H16N4O2/c22-16-11-5-3-6-12(15(11)13-7-4-10-21(13)16)19-17(23)20-14-8-1-2-9-18-14/h1-3,5-6,8-9,13H,4,7,10H2,(H2,18,19,20,23)	KLVYMYQTRZCMLE-UHFFFAOYSA-N	6619	3-[(9bR)-5-oxo-1H,2H,3H,5H,9bH-benzo[a]pyrrolizin-9-yl]-1-pyridin-2-ylurea::CHEMBL141247::Pyridin-2-yl urea::N -(pyrrolidino[2,1-b]isoindolin-4-on-8-yl)-N-(pyridin-2yl)urea::diarylurea deriv. 1	Epidermal growth factor receptor	Homo sapiens		>20000					7.0000	22.00 C	Curated from the literature by BindingDB	10.1021/jm010326y	10.7270/Q2BV7DS8	11741480	aid1795920		Honma, T; Yoshizumi, T; Hashimoto, N; Hayashi, K; Kawanishi, N; Fukasawa, K; Takaki, T; Ikeura, C; Ikuta, M; Suzuki-Takahashi, I; Hayama, T; Nishimura, S; Morishima, H	12/20/2001	12/6/2005	Banyu Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6619	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6619&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			445840	8036196		CHEMBL141247	DB04186				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
11535	c1cc(c(c(c1)F)C(=O)n2c(nc(n2)Nc3ccc(cc3)S(=O)(=O)N)N)F	InChI=1S/C15H12F2N6O3S/c16-10-2-1-3-11(17)12(10)13(24)23-14(18)21-15(22-23)20-8-4-6-9(7-5-8)27(19,25)26/h1-7H,(H2,19,25,26)(H3,18,20,21,22)	KDKUVYLMPJIGKA-UHFFFAOYSA-N	6866	1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b::4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzene-1-sulfonamide::4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]-benzenesulfonamide::CHEMBL191003::cid_5330790::JNJ-7706621::US12110278, Compound 1::US20250034112, Compound 1	Epidermal growth factor receptor	Homo sapiens		>100000							Curated from the literature by BindingDB	10.1021/jm050267e	10.7270/Q22F7KNX	15974571	aid1795974		Lin, R; Connolly, PJ; Huang, S; Wetter, SK; Lu, Y; Murray, WV; Emanuel, SL; Gruninger, RH; Fuentes-Pesquera, AR; Rugg, CA; Middleton, SA; Jolliffe, LK	6/30/2005	12/22/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6866	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6866&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	SKE	5WIN,5USZ,5USY,5DR9,8B99,5OBR,6DRW,5DPV,5DR6,6P11,6P10,3AMA,4QMU,5DT0	5330790	8036422		CHEMBL191003					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
11536	Cc1ccc(F)c(C(=O)n2nc(Nc3ccc(cc3)S(N)(=O)=O)nc2N)c1F	InChI=1S/C16H14F2N6O3S/c1-8-2-7-11(17)12(13(8)18)14(25)24-15(19)22-16(23-24)21-9-3-5-10(6-4-9)28(20,26)27/h2-7H,1H3,(H2,20,26,27)(H3,19,21,22,23)	IEWLQUDDCQIINQ-UHFFFAOYSA-N	6867	4-({5-amino-1-[(2,6-difluoro-3-methylphenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzene-1-sulfonamide::4-[[5-Amino-1-(2,6-difluoro-3-methylbenzoyl)-1H-1,2,4-triazol-3-yl]amino]-benzenesulfonamide::1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3c	Epidermal growth factor receptor	Homo sapiens		 45800							Curated from the literature by BindingDB	10.1021/jm050267e	10.7270/Q22F7KNX	15974571	aid1795974		Lin, R; Connolly, PJ; Huang, S; Wetter, SK; Lu, Y; Murray, WV; Emanuel, SL; Gruninger, RH; Fuentes-Pesquera, AR; Rugg, CA; Middleton, SA; Jolliffe, LK	6/30/2005	12/22/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6867&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330800	8036432							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
11537	Cc1ccsc1C(=O)n1nc(Nc2ccc(cc2)S(N)(=O)=O)nc1N	InChI=1S/C14H14N6O3S2/c1-8-6-7-24-11(8)12(21)20-13(15)18-14(19-20)17-9-2-4-10(5-3-9)25(16,22)23/h2-7H,1H3,(H2,16,22,23)(H3,15,17,18,19)	KQWTXAWKBUUOMU-UHFFFAOYSA-N	6870	4-({5-amino-1-[(3-methylthiophen-2-yl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzene-1-sulfonamide::4-[[5-Amino-1-[(3-methyl-2-thienyl)carbonyl]-1H-1,2,4-triazol-3-yl]amino]-benzenesulfonamide::1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f	Epidermal growth factor receptor	Homo sapiens		 8400							Curated from the literature by BindingDB	10.1021/jm050267e	10.7270/Q22F7KNX	15974571	aid1795974		Lin, R; Connolly, PJ; Huang, S; Wetter, SK; Lu, Y; Murray, WV; Emanuel, SL; Gruninger, RH; Fuentes-Pesquera, AR; Rugg, CA; Middleton, SA; Jolliffe, LK	6/30/2005	12/22/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6870&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5330804	8036436							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
11538	c1cc(c(c(c1)F)NC(=S)n2c(nc(n2)Nc3ccc(cc3)S(=O)(=O)N)N)F	InChI=1S/C15H13F2N7O2S2/c16-10-2-1-3-11(17)12(10)21-15(27)24-13(18)22-14(23-24)20-8-4-6-9(7-5-8)28(19,25)26/h1-7H,(H,21,27)(H2,19,25,26)(H3,18,20,22,23)	ARIOBGGRZJITQX-UHFFFAOYSA-N	6878	5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbothioamide::1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n	Epidermal growth factor receptor	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1021/jm050267e	10.7270/Q22F7KNX	15974571	aid1795974		Lin, R; Connolly, PJ; Huang, S; Wetter, SK; Lu, Y; Murray, WV; Emanuel, SL; Gruninger, RH; Fuentes-Pesquera, AR; Rugg, CA; Middleton, SA; Jolliffe, LK	6/30/2005	12/22/2005	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6878	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6878&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	DKI	3LJ1,2CHL,4FZF,4AAA,2J51,3HMI,2JFL,4QMP,2W4O,2WU6	5330812	8036444			DB07664				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24948	CCOC(=O)c1cn2ncnc(Nc3ccc(F)c(Cl)c3)c2c1CC	InChI=1S/C17H16ClFN4O2/c1-3-11-12(17(24)25-4-2)8-23-15(11)16(20-9-21-23)22-10-5-6-14(19)13(18)7-10/h5-9H,3-4H2,1-2H3,(H,20,21,22)	DCVODVBLQRXBMG-UHFFFAOYSA-N	13900	ethyl 4-[(3-chloro-4-fluorophenyl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::CHEMBL196018::pyrrolo[2,1-f][1,2,4]triazine analog 5a	Epidermal growth factor receptor	Homo sapiens		 90							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13900	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13900&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646535	46514278		CHEMBL196018					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24949	CCOC(=O)c1cn2ncnc(Nc3cccc(Br)c3)c2c1CC	InChI=1S/C17H17BrN4O2/c1-3-13-14(17(23)24-4-2)9-22-15(13)16(19-10-20-22)21-12-7-5-6-11(18)8-12/h5-10H,3-4H2,1-2H3,(H,19,20,21)	ZCKGARDCKJFLRH-UHFFFAOYSA-N	13901	ethyl 4-[(3-bromophenyl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::CHEMBL370934::pyrrolo[2,1-f][1,2,4]triazine analog 5b	Epidermal growth factor receptor	Homo sapiens		 60							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13901	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13901&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646536	46514279		CHEMBL370934					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24950	CCOC(=O)c1cn2ncnc(Nc3ccc4[nH]ncc4c3)c2c1CC	InChI=1S/C18H18N6O2/c1-3-13-14(18(25)26-4-2)9-24-16(13)17(19-10-21-24)22-12-5-6-15-11(7-12)8-20-23-15/h5-10H,3-4H2,1-2H3,(H,20,23)(H,19,21,22)	XSFGXVBMHUSTNL-UHFFFAOYSA-N	13902	CHEMBL372112::ethyl 5-ethyl-4-(1H-indazol-5-ylamino)pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5c	Epidermal growth factor receptor	Homo sapiens		 50							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13902	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13902&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646537	46514280		CHEMBL372112					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24951	CCOC(=O)c1cn2ncnc(N[C@H](C)c3ccccc3)c2c1CC |r|	InChI=1S/C19H22N4O2/c1-4-15-16(19(24)25-5-2)11-23-17(15)18(20-12-21-23)22-13(3)14-9-7-6-8-10-14/h6-13H,4-5H2,1-3H3,(H,20,21,22)	IKFNDVGENZZACI-UHFFFAOYSA-N	13903	ethyl 5-ethyl-4-{[(1R)-1-phenylethyl]amino}pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5d	Epidermal growth factor receptor	Homo sapiens		 200							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13903	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13903&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646538	46514281							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24952	CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC	InChI=1S/C25H24N6O2/c1-3-20-21(25(32)33-4-2)15-31-23(20)24(26-16-28-31)29-19-10-11-22-18(12-19)13-27-30(22)14-17-8-6-5-7-9-17/h5-13,15-16H,3-4,14H2,1-2H3,(H,26,28,29)	DLQGOUYSCARQKO-UHFFFAOYSA-N	13904	CHEMBL196925::ethyl 4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5e	Epidermal growth factor receptor	Homo sapiens		 120							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13904	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13904&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23589545	46514282		CHEMBL196925					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24953	CCOC(=O)c1cn2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2c1CC	InChI=1S/C23H22N4O3/c1-3-19-20(23(28)29-4-2)14-27-21(19)22(24-15-25-27)26-16-10-12-18(13-11-16)30-17-8-6-5-7-9-17/h5-15H,3-4H2,1-2H3,(H,24,25,26)	SXUTWMUWKOLBDA-UHFFFAOYSA-N	13905	CHEMBL194349::ethyl 5-ethyl-4-[(4-phenoxyphenyl)amino]pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5f	Epidermal growth factor receptor	Homo sapiens		 610							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13905	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13905&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646539	46514283		CHEMBL194349					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24954	CCOC(=O)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnn2c1	InChI=1S/C23H20N6O2/c1-2-31-23(30)18-11-21-22(24-15-26-29(21)14-18)27-19-8-9-20-17(10-19)12-25-28(20)13-16-6-4-3-5-7-16/h3-12,14-15H,2,13H2,1H3,(H,24,26,27)	KBVZETYUCGGMRC-UHFFFAOYSA-N	13906	CHEMBL425738::ethyl 4-[(1-benzyl-1H-indazol-5-yl)amino]pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5g	Epidermal growth factor receptor	Homo sapiens		 120							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13906&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646540	46514284		CHEMBL425738					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24955	CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1C	InChI=1S/C24H22N6O2/c1-3-32-24(31)20-14-30-22(16(20)2)23(25-15-27-30)28-19-9-10-21-18(11-19)12-26-29(21)13-17-7-5-4-6-8-17/h4-12,14-15H,3,13H2,1-2H3,(H,25,27,28)	GPXPDUOFHSGRBJ-UHFFFAOYSA-N	13907	ethyl 4-[(1-benzyl-1H-indazol-5-yl)amino]-5-methylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::CHEMBL196738::pyrrolo[2,1-f][1,2,4]triazine analog 5h	Epidermal growth factor receptor	Homo sapiens		 200							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13907	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13907&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646541	46514285		CHEMBL196738					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24956	CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1C(C)C	InChI=1S/C26H26N6O2/c1-4-34-26(33)21-15-32-24(23(21)17(2)3)25(27-16-29-32)30-20-10-11-22-19(12-20)13-28-31(22)14-18-8-6-5-7-9-18/h5-13,15-17H,4,14H2,1-3H3,(H,27,29,30)	DLACNDICKJWAMH-UHFFFAOYSA-N	13908	CHEMBL365606::ethyl 4-[(1-benzyl-1H-indazol-5-yl)amino]-5-(propan-2-yl)pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5i	Epidermal growth factor receptor	Homo sapiens		 200							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13908&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646542	46514286		CHEMBL365606					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24957	CCCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)OCC	InChI=1S/C26H26N6O2/c1-3-8-21-22(26(33)34-4-2)16-32-24(21)25(27-17-29-32)30-20-11-12-23-19(13-20)14-28-31(23)15-18-9-6-5-7-10-18/h5-7,9-14,16-17H,3-4,8,15H2,1-2H3,(H,27,29,30)	VRGOWRHHJHLAFC-UHFFFAOYSA-N	13909	ethyl 4-[(1-benzyl-1H-indazol-5-yl)amino]-5-propylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::CHEMBL438805::pyrrolo[2,1-f][1,2,4]triazine analog 5j	Epidermal growth factor receptor	Homo sapiens		 950							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13909	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13909&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23589555	46514287		CHEMBL438805					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24958	CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1Cc1ccccc1	InChI=1S/C30H26N6O2/c1-2-38-30(37)26-19-36-28(25(26)15-21-9-5-3-6-10-21)29(31-20-33-36)34-24-13-14-27-23(16-24)17-32-35(27)18-22-11-7-4-8-12-22/h3-14,16-17,19-20H,2,15,18H2,1H3,(H,31,33,34)	MVZAPDAYTFZUSI-UHFFFAOYSA-N	13910	ethyl 5-benzyl-4-[(1-benzyl-1H-indazol-5-yl)amino]pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::CHEMBL197568::pyrrolo[2,1-f][1,2,4]triazine analog 5k	Epidermal growth factor receptor	Homo sapiens		>25000							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13910	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13910&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646543	46514288		CHEMBL197568					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24959	CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(O)=O	InChI=1S/C23H20N6O2/c1-2-18-19(23(30)31)13-29-21(18)22(24-14-26-29)27-17-8-9-20-16(10-17)11-25-28(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H,30,31)(H,24,26,27)	WHYDOZDJTWFLEP-UHFFFAOYSA-N	13911	4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylic acid::CHEMBL196438::pyrrolo[2,1-f][1,2,4]triazine analog 6	Epidermal growth factor receptor	Homo sapiens		 20							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13911	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13911&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16730263	46514289		CHEMBL196438					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24960	CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(N)=O	InChI=1S/C23H21N7O/c1-2-18-19(22(24)31)13-30-21(18)23(25-14-27-30)28-17-8-9-20-16(10-17)11-26-29(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H2,24,31)(H,25,27,28)	UMFUSRXYNCISOO-UHFFFAOYSA-N	13912	CHEMBL194958::4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide::pyrrolo[2,1-f][1,2,4]triazine analog 7a	Epidermal growth factor receptor	Homo sapiens		 120							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13912	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13912&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646544	46514290		CHEMBL194958					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24961	CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NC	InChI=1S/C24H23N7O/c1-3-19-20(24(32)25-2)14-31-22(19)23(26-15-28-31)29-18-9-10-21-17(11-18)12-27-30(21)13-16-7-5-4-6-8-16/h4-12,14-15H,3,13H2,1-2H3,(H,25,32)(H,26,28,29)	XSUGKVVBKGFATM-UHFFFAOYSA-N	13913	4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-methylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide::CHEMBL197689::pyrrolo[2,1-f][1,2,4]triazine analog 7b	Epidermal growth factor receptor	Homo sapiens		 70							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13913	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13913&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646545	46514291		CHEMBL197689					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24962	CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)N(C)C	InChI=1S/C25H25N7O/c1-4-20-21(25(33)30(2)3)15-32-23(20)24(26-16-28-32)29-19-10-11-22-18(12-19)13-27-31(22)14-17-8-6-5-7-9-17/h5-13,15-16H,4,14H2,1-3H3,(H,26,28,29)	FAFIJKWOYIPTEN-UHFFFAOYSA-N	13914	CHEMBL372293::4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N,N-dimethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide::pyrrolo[2,1-f][1,2,4]triazine analog 7c	Epidermal growth factor receptor	Homo sapiens		 200							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13914	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13914&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			21945841	46514292		CHEMBL372293					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24963	CCc1c(NC(=O)OCc2ccccc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12	InChI=1S/C30H27N7O2/c1-2-25-26(35-30(38)39-19-22-11-7-4-8-12-22)18-37-28(25)29(31-20-33-37)34-24-13-14-27-23(15-24)16-32-36(27)17-21-9-5-3-6-10-21/h3-16,18,20H,2,17,19H2,1H3,(H,35,38)(H,31,33,34)	MHHWMILMVAWLOJ-UHFFFAOYSA-N	13915	benzyl N-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}carbamate::CHEMBL372523::pyrrolo[2,1-f][1,2,4]triazine analog 9a	Epidermal growth factor receptor	Homo sapiens		 210							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13915	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13915&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646546	46514293		CHEMBL372523					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24964	CCc1c(CO)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12	InChI=1S/C23H22N6O/c1-2-20-18(14-30)13-29-22(20)23(24-15-26-29)27-19-8-9-21-17(10-19)11-25-28(21)12-16-6-4-3-5-7-16/h3-11,13,15,30H,2,12,14H2,1H3,(H,24,26,27)	RVFNMWDKGFLUFT-UHFFFAOYSA-N	13916	CHEMBL373025::{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}methanol::pyrrolo[2,1-f][1,2,4]triazine analog 10	Epidermal growth factor receptor	Homo sapiens		 490							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13916	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13916&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			21945809	46514294		CHEMBL373025					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24965	CCNCc1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC	InChI=1S/C25H27N7/c1-3-22-20(13-26-4-2)16-32-24(22)25(27-17-29-32)30-21-10-11-23-19(12-21)14-28-31(23)15-18-8-6-5-7-9-18/h5-12,14,16-17,26H,3-4,13,15H2,1-2H3,(H,27,29,30)	XLQRPZAGFWJWJE-UHFFFAOYSA-N	13917	1-benzyl-N-{5-ethyl-6-[(ethylamino)methyl]pyrrolo[1,2-a][1,2,4]triazin-4-yl}-1H-indazol-5-amine::CHEMBL369967::pyrrolo[2,1-f][1,2,4]triazine analog 11	Epidermal growth factor receptor	Homo sapiens		 7400							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13917	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13917&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646547	46514295		CHEMBL369967					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24966	CCOCc1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC	InChI=1S/C25H26N6O/c1-3-22-20(16-32-4-2)15-31-24(22)25(26-17-28-31)29-21-10-11-23-19(12-21)13-27-30(23)14-18-8-6-5-7-9-18/h5-13,15,17H,3-4,14,16H2,1-2H3,(H,26,28,29)	CBDBASHBUAODSV-UHFFFAOYSA-N	13918	CHEMBL196548::1-benzyl-N-[6-(ethoxymethyl)-5-ethylpyrrolo[1,2-a][1,2,4]triazin-4-yl]-1H-indazol-5-amine::pyrrolo[2,1-f][1,2,4]triazine analog 12	Epidermal growth factor receptor	Homo sapiens		 950							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13918	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13918&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646548	46514296		CHEMBL196548					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24967	CCc1c(CC(N)=O)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12	InChI=1S/C24H23N7O/c1-2-20-18(11-22(25)32)14-31-23(20)24(26-15-28-31)29-19-8-9-21-17(10-19)12-27-30(21)13-16-6-4-3-5-7-16/h3-10,12,14-15H,2,11,13H2,1H3,(H2,25,32)(H,26,28,29)	LVLMWYNJGBBWEX-UHFFFAOYSA-N	13919	2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}acetamide::CHEMBL194160::pyrrolo[2,1-f][1,2,4]triazine analog 13	Epidermal growth factor receptor	Homo sapiens		 1100							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13919&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646549	46514297		CHEMBL194160					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24968	CCc1c(CC(O)=O)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12	InChI=1S/C24H22N6O2/c1-2-20-18(11-22(31)32)14-30-23(20)24(25-15-27-30)28-19-8-9-21-17(10-19)12-26-29(21)13-16-6-4-3-5-7-16/h3-10,12,14-15H,2,11,13H2,1H3,(H,31,32)(H,25,27,28)	NFCDGHRKDYRHJM-UHFFFAOYSA-N	13920	CHEMBL372692::2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}acetic acid::pyrrolo[2,1-f][1,2,4]triazine analog 14	Epidermal growth factor receptor	Homo sapiens		 1600							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13920	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13920&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23644675	46509430		CHEMBL372692					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24969	CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NCCCn1ccnc1	InChI=1S/C29H29N9O/c1-2-24-25(29(39)31-11-6-13-36-14-12-30-20-36)18-38-27(24)28(32-19-34-38)35-23-9-10-26-22(15-23)16-33-37(26)17-21-7-4-3-5-8-21/h3-5,7-10,12,14-16,18-20H,2,6,11,13,17H2,1H3,(H,31,39)(H,32,34,35)	TYIJYIGEKOSLCM-UHFFFAOYSA-N	13921	CHEMBL193681::4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(1H-imidazol-1-yl)propyl]pyrrolo[1,2-a][1,2,4]triazine-6-carboxamide::pyrrolo[2,1-f][1,2,4]triazine analog 7d	Epidermal growth factor receptor	Homo sapiens		 40							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13921	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13921&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			21945968	46514298		CHEMBL193681					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24970	CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)OCCCn1ccnc1	InChI=1S/C29H28N8O2/c1-2-24-25(29(38)39-14-6-12-35-13-11-30-20-35)18-37-27(24)28(31-19-33-37)34-23-9-10-26-22(15-23)16-32-36(26)17-21-7-4-3-5-8-21/h3-5,7-11,13,15-16,18-20H,2,6,12,14,17H2,1H3,(H,31,33,34)	CQTPFJKIPFEALQ-UHFFFAOYSA-N	13922	3-(1H-imidazol-1-yl)propyl 4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::CHEMBL193368::pyrrolo[2,1-f][1,2,4]triazine analog 8a	Epidermal growth factor receptor	Homo sapiens		 170							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13922	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13922&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			23646550	46514299		CHEMBL193368					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
24971	CCc1c(NC(=O)OCCn2ccnc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12	InChI=1S/C28H27N9O2/c1-2-23-24(34-28(38)39-13-12-35-11-10-29-19-35)17-37-26(23)27(30-18-32-37)33-22-8-9-25-21(14-22)15-31-36(25)16-20-6-4-3-5-7-20/h3-11,14-15,17-19H,2,12-13,16H2,1H3,(H,34,38)(H,30,32,33)	VTLGISZPEUFMGV-UHFFFAOYSA-N	13923	2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}carbamate::CHEMBL412367::pyrrolo[2,1-f][1,2,4]triazine analog 9b	Epidermal growth factor receptor	Homo sapiens		 40							Curated from the literature by BindingDB	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	9/26/2005	11/10/2009	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13923	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13923&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9871380	46514300		CHEMBL412367					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39758	Fc1ccc(Nc2c(cnc3ccc(NCc4cnc[nH]4)cc23)C#N)cc1Cl	InChI=1S/C20H14ClFN6/c21-17-6-14(1-3-18(17)22)28-20-12(7-23)8-26-19-4-2-13(5-16(19)20)25-10-15-9-24-11-27-15/h1-6,8-9,11,25H,10H2,(H,24,27)(H,26,28)	HFOOHVUKODGHBP-UHFFFAOYSA-N	21896	BMCL193485 Compound 2::CHEMBL220037::4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 2	Epidermal growth factor receptor	Homo sapiens		 30							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21896	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21896&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16066845	49701000		CHEMBL220037					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39759	Fc1ccc(Nc2c(cnc3c(F)cc(NCc4cnc[nH]4)cc23)C#N)cc1Cl	InChI=1S/C20H13ClF2N6/c21-16-4-12(1-2-17(16)22)29-19-11(6-24)7-27-20-15(19)3-13(5-18(20)23)26-9-14-8-25-10-28-14/h1-5,7-8,10,26H,9H2,(H,25,28)(H,27,29)	GRPUCYCKBBWGEO-UHFFFAOYSA-N	21897	4-[(3-chloro-4-fluorophenyl)amino]-8-fluoro-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 10	Epidermal growth factor receptor	Homo sapiens		 500							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21897	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21897&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17758240	49701001							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39760	Fc1ccc(Nc2c(cnc3c(Cl)cc(NCc4cnc[nH]4)cc23)C#N)cc1Cl	InChI=1S/C20H13Cl2FN6/c21-16-4-12(1-2-18(16)23)29-19-11(6-24)7-27-20-15(19)3-13(5-17(20)22)26-9-14-8-25-10-28-14/h1-5,7-8,10,26H,9H2,(H,25,28)(H,27,29)	ONXROKMQGCSOMG-UHFFFAOYSA-N	21898	8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile::CHEMBL436817::Cyanoquinoline, 11	Epidermal growth factor receptor	Homo sapiens		 1800							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21898	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21898&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17759555	49701002		CHEMBL436817					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39761	Fc1ccc(Nc2c(cnc3c(Br)cc(NCc4cnc[nH]4)cc23)C#N)cc1Cl	InChI=1S/C20H13BrClFN6/c21-16-4-13(26-9-14-8-25-10-28-14)3-15-19(11(6-24)7-27-20(15)16)29-12-1-2-18(23)17(22)5-12/h1-5,7-8,10,26H,9H2,(H,25,28)(H,27,29)	SKFFXBWGYMDLSC-UHFFFAOYSA-N	21899	8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 12	Epidermal growth factor receptor	Homo sapiens		 3300							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21899	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21899&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17758241	49701003							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39762	Fc1ccc(Nc2c(cnc3c(cc(NCc4cnc[nH]4)cc23)C(F)(F)F)C#N)cc1Cl	InChI=1S/C21H13ClF4N6/c22-17-5-12(1-2-18(17)23)32-19-11(6-27)7-30-20-15(19)3-13(4-16(20)21(24,25)26)29-9-14-8-28-10-31-14/h1-5,7-8,10,29H,9H2,(H,28,31)(H,30,32)	VNDJQGZFTOLUSU-UHFFFAOYSA-N	21900	4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]-8-(trifluoromethyl)quinoline-3-carbonitrile::Cyanoquinoline, 13	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21900	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21900&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17759556	49701004							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39763	COc1cc(NCc2cnc[nH]2)cc2c(Nc3ccc(F)c(Cl)c3)c(cnc12)C#N	InChI=1S/C21H16ClFN6O/c1-30-19-6-14(26-10-15-9-25-11-28-15)4-16-20(12(7-24)8-27-21(16)19)29-13-2-3-18(23)17(22)5-13/h2-6,8-9,11,26H,10H2,1H3,(H,25,28)(H,27,29)	KPQYADFSXWRWHU-UHFFFAOYSA-N	21902	4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]-8-methoxyquinoline-3-carbonitrile::Cyanoquinoline, 15	Epidermal growth factor receptor	Homo sapiens		 2080							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21902	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21902&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17759673	49701006							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39764	CS(=O)c1cc(NCc2cnc[nH]2)cc2c(Nc3ccc(F)c(Cl)c3)c(cnc12)C#N	InChI=1S/C21H16ClFN6OS/c1-31(30)19-6-14(26-10-15-9-25-11-28-15)4-16-20(12(7-24)8-27-21(16)19)29-13-2-3-18(23)17(22)5-13/h2-6,8-9,11,26H,10H2,1H3,(H,25,28)(H,27,29)	VISPUVFNHYLBPQ-UHFFFAOYSA-N	21903	4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]-8-methanesulfinylquinoline-3-carbonitrile::Cyanoquinoline, 16	Epidermal growth factor receptor	Homo sapiens		 5000							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21903	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21903&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17758353	49701007							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39765	CN(C)C(=O)c1cc(NCc2cnc[nH]2)cc2c(Nc3ccc(F)c(Cl)c3)c(cnc12)C#N	InChI=1S/C23H19ClFN7O/c1-32(2)23(33)18-6-15(28-11-16-10-27-12-30-16)5-17-21(13(8-26)9-29-22(17)18)31-14-3-4-20(25)19(24)7-14/h3-7,9-10,12,28H,11H2,1-2H3,(H,27,30)(H,29,31)	QCSDGVKAAVVIBF-UHFFFAOYSA-N	21905	4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-6-[(1H-imidazol-4-ylmethyl)amino]-N,N-dimethylquinoline-8-carboxamide::Cyanoquinoline, 18	Epidermal growth factor receptor	Homo sapiens		>20000							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21905	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21905&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17759675	49701009							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39766	CC(=O)c1cc(NCc2cnc[nH]2)cc2c(Nc3ccc(F)c(Cl)c3)c(cnc12)C#N	InChI=1S/C22H16ClFN6O/c1-12(31)17-4-15(27-10-16-9-26-11-29-16)5-18-21(13(7-25)8-28-22(17)18)30-14-2-3-20(24)19(23)6-14/h2-6,8-9,11,27H,10H2,1H3,(H,26,29)(H,28,30)	FYBDFTOKGKWXLM-UHFFFAOYSA-N	21906	4-[(3-chloro-4-fluorophenyl)amino]-8-acetyl-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 19	Epidermal growth factor receptor	Homo sapiens		 156							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21906&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17758354	49701010							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39767	Fc1ccc(Nc2c(cnc3c(Cl)cc(NCc4cccnc4)cc23)C#N)cc1Cl	InChI=1S/C22H14Cl2FN5/c23-18-7-15(3-4-20(18)25)30-21-14(9-26)12-29-22-17(21)6-16(8-19(22)24)28-11-13-2-1-5-27-10-13/h1-8,10,12,28H,11H2,(H,29,30)	VERMEYXVPILBCD-UHFFFAOYSA-N	21915	8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(pyridin-3-ylmethyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 28	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21915	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21915&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17758358	49701019							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39768	[O-][n+]1ccccc1CNc1cc(Cl)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1	InChI=1S/C22H14Cl2FN5O/c23-18-8-14(4-5-20(18)25)29-21-13(10-26)11-28-22-17(21)7-15(9-19(22)24)27-12-16-3-1-2-6-30(16)31/h1-9,11,27H,12H2,(H,28,29)	ORVPEVIDEJOHIY-UHFFFAOYSA-N	21920	2-[({8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-3-cyanoquinolin-6-yl}amino)methyl]-1-oxidopyridin-1-ium::Cyanoquinoline, 33	Epidermal growth factor receptor	Homo sapiens		 2900							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21920	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21920&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17759787	49701024							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39769	Fc1ccc(Nc2c(cnc3c(Br)cc(NCc4cnn[nH]4)cc23)C#N)cc1Cl	InChI=1S/C19H12BrClFN7/c20-15-4-12(24-8-13-9-26-29-28-13)3-14-18(10(6-23)7-25-19(14)15)27-11-1-2-17(22)16(21)5-11/h1-5,7,9,24H,8H2,(H,25,27)(H,26,28,29)	KEZDJRADZYWSSG-UHFFFAOYSA-N	21925	8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-1,2,3-triazol-4-ylmethyl)amino]quinoline-3-carbonitrile::BMCL193485 Compound 8::Cyanoquinoline, 51	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21925	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21925&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17758019	49701029							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
39770	CN(C)CCCn1cc(CNc2cc(Br)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)nn1	InChI=1S/C24H23BrClFN8/c1-34(2)6-3-7-35-14-18(32-33-35)13-29-17-8-19-23(31-16-4-5-22(27)21(26)10-16)15(11-28)12-30-24(19)20(25)9-17/h4-5,8-10,12,14,29H,3,6-7,13H2,1-2H3,(H,30,31)	RUCXDAGQSXXFMK-UHFFFAOYSA-N	21926	8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[({1-[3-(dimethylamino)propyl]-1H-1,2,3-triazol-4-yl}methyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 55	Epidermal growth factor receptor	Homo sapiens		>5000							Curated from the literature by BindingDB	10.1021/jm070436q	10.7270/Q2891441	17715908	aid1798141		Green, N; Hu, Y; Janz, K; Li, HQ; Kaila, N; Guler, S; Thomason, J; Joseph-McCarthy, D; Tam, SY; Hotchandani, R; Wu, J; Huang, A; Wang, Q; Leung, L; Pelker, J; Marusic, S; Hsu, S; Telliez, JB; Hall, JP; Cuozzo, JW; Lin, LL	9/20/2007	4/30/2008	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21926	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21926&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			17758020	49701030							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
44874	CC1(CNc2c1ccc(c2)NC(=O)c3cccnc3NCc4ccncc4)C	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::cid_11667893::AMG-706::Motesanib::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::AMG 706::US10464902, Motesanib	Epidermal growth factor receptor	Homo sapiens		>3000					7.5000	22.00 C	Curated from the literature by BindingDB	10.1158/0008-5472.CAN-05-4665	10.7270/Q2057D73	16951187	aid1798470		Polverino, A; Coxon, A; Starnes, C; Diaz, Z; DeMelfi, T; Wang, L; Bready, J; Estrada, J; Cattley, R; Kaufman, S; Chen, D; Gan, Y; Kumar, G; Meyer, J; Neervannan, S; Alva, G; Talvenheimo, J; Montestruque, S; Tasker, A; Patel, V; Radinsky, R; Kendall, R	9/1/2006	10/13/2008	Amgen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
47427	COc1cc2c(cc1OCCCN3CCOCC3)c(ncn2)Nc4ccc(c(c4)Cl)F	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	ZD1839::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::cid_123631::CHEMBL939::GEFITINIB::Iressa::US9416123, Gefitinib::US10106508, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::US10507209, Compound Gefitinib::WO2022090481, Example gefitinib	Epidermal growth factor receptor	Homo sapiens			 53.5				7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.ccr.2006.12.017	10.7270/Q2JQ0ZBW	17349580	aid1798633		Yun, CH; Boggon, TJ; Li, Y; Woo, MS; Greulich, H; Meyerson, M; Eck, MJ	3/28/2007	12/18/2008	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	IRE	2ITZ,2ITY,2ITO,5Y7Z,4WKQ,4I22,5Y80,3UG2	123631	8035066		CHEMBL939	DB00317				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
47428	CCN1CCN(Cc2ccc(cc2)-c2cc3c(N[C@H](C)c4ccccc4)ncnc3[nH]2)CC1 |r|	InChI=1S/C27H32N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,17,19-20H,3,13-16,18H2,1-2H3,(H2,28,29,30,31)	OONFNUWBHFSNBT-UHFFFAOYSA-N	26105	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine::AEE788	Epidermal growth factor receptor	Homo sapiens			 10.9				7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.ccr.2006.12.017	10.7270/Q2JQ0ZBW	17349580	aid1798633		Yun, CH; Boggon, TJ; Li, Y; Woo, MS; Greulich, H; Meyerson, M; Eck, MJ	3/28/2007	12/18/2008	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26105&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10297043	56464542							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
47433	COc1cc2c(cc1OCCCN3CCOCC3)c(ncn2)Nc4ccc(c(c4)Cl)F	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	ZD1839::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::cid_123631::CHEMBL939::GEFITINIB::Iressa::US9416123, Gefitinib::US10106508, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::US10507209, Compound Gefitinib::WO2022090481, Example gefitinib	Epidermal growth factor receptor	Homo sapiens			 35.3				7.4000	22.00 C	Curated from the literature by BindingDB	10.1073/pnas.0709662105	10.7270/Q2DZ06MJ	18227510	aid1798634		Yun, CH; Mengwasser, KE; Toms, AV; Woo, MS; Greulich, H; Wong, KK; Meyerson, M; Eck, MJ	2/12/2008	12/15/2008	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	IRE	2ITZ,2ITY,2ITO,5Y7Z,4WKQ,4I22,5Y80,3UG2	123631	8035066		CHEMBL939	DB00317				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
47434	CCN1CCN(Cc2ccc(cc2)-c2cc3c(N[C@H](C)c4ccccc4)ncnc3[nH]2)CC1 |r|	InChI=1S/C27H32N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,17,19-20H,3,13-16,18H2,1-2H3,(H2,28,29,30,31)	OONFNUWBHFSNBT-UHFFFAOYSA-N	26105	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine::AEE788	Epidermal growth factor receptor	Homo sapiens			 5.3				7.4000	22.00 C	Curated from the literature by BindingDB	10.1073/pnas.0709662105	10.7270/Q2DZ06MJ	18227510	aid1798634		Yun, CH; Mengwasser, KE; Toms, AV; Woo, MS; Greulich, H; Wong, KK; Meyerson, M; Eck, MJ	2/12/2008	12/15/2008	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26105&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10297043	56464542							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51111	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C)cc2Cl)c1	InChI=1S/C21H13ClFN3OS/c1-2-16-10-18-20(28-16)21(25-12-24-18)26-15-6-7-19(17(22)9-15)27-11-13-4-3-5-14(23)8-13/h1,3-10,12H,11H2,(H,24,25,26)	RBBZLSVNHVBMRU-UHFFFAOYSA-N	27971	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-ethynylthieno[3,2-d]pyrimidin-4-amine::6-Ethynylthieno[3,2-d]pyrimidine, 6	Epidermal growth factor receptor	Homo sapiens		 24					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27971	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27971&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10309835	57560483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51112	C[C@H](N)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C23H18ClFN4OS/c1-14(26)5-7-18-11-20-22(31-18)23(28-13-27-20)29-17-6-8-21(19(24)10-17)30-12-15-3-2-4-16(25)9-15/h2-4,6,8-11,13-14H,12,26H2,1H3,(H,27,28,29)	DWJSVGCODPLRLP-UHFFFAOYSA-N	27972	6-[(3S)-3-aminobut-1-yn-1-yl]-N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}thieno[3,2-d]pyrimidin-4-amine::6-Ethynylthieno[3,2-d]pyrimidine, 7	Epidermal growth factor receptor	Homo sapiens		 64					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27972&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218694	57560484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51113	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@H]3CCCN3)cc2Cl)c1 |r|	InChI=1S/C25H20ClFN4OS/c26-21-12-19(7-9-23(21)32-14-16-3-1-4-17(27)11-16)31-25-24-22(29-15-30-25)13-20(33-24)8-6-18-5-2-10-28-18/h1,3-4,7,9,11-13,15,18,28H,2,5,10,14H2,(H,29,30,31)	FNYHTKUCTLSINN-UHFFFAOYSA-N	27973	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{2-[(2R)-pyrrolidin-2-yl]ethynyl}thieno[3,2-d]pyrimidin-4-amine::6-Ethynylthieno[3,2-d]pyrimidine, 8	Epidermal growth factor receptor	Homo sapiens		 7					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27973	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27973&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11420204	57560485							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51114	Nc1cnc(cn1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1	InChI=1S/C25H16ClFN6OS/c26-20-9-17(5-7-22(20)34-13-15-2-1-3-16(27)8-15)33-25-24-21(31-14-32-25)10-19(35-24)6-4-18-11-30-23(28)12-29-18/h1-3,5,7-12,14H,13H2,(H2,28,30)(H,31,32,33)	KWBKHNYGQSAYCE-UHFFFAOYSA-N	27974	5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrazin-2-amine::6-Ethynylthieno[3,2-d]pyrimidine, 9	Epidermal growth factor receptor	Homo sapiens		 47					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27974	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27974&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11420697	57560486							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51115	Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)C#C)cc2Cl)c1	InChI=1S/C21H13ClFN3OS/c1-2-16-10-17-20(24-12-25-21(17)28-16)26-15-6-7-19(18(22)9-15)27-11-13-4-3-5-14(23)8-13/h1,3-10,12H,11H2,(H,24,25,26)	POJRAIDOFSJODM-UHFFFAOYSA-N	27975	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-ethynylthieno[2,3-d]pyrimidin-4-amine::6-Ethynylthieno[2,3-d]pyrimidine, 10	Epidermal growth factor receptor	Homo sapiens		 71					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27975	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27975&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218695	57560487							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51116	C[C@H](N)C#Cc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2s1 |r|	InChI=1S/C23H18ClFN4OS/c1-14(26)5-7-18-11-19-22(27-13-28-23(19)31-18)29-17-6-8-21(20(24)10-17)30-12-15-3-2-4-16(25)9-15/h2-4,6,8-11,13-14H,12,26H2,1H3,(H,27,28,29)	UMGYMAXDIGYRMA-UHFFFAOYSA-N	27976	6-[(3S)-3-aminobut-1-yn-1-yl]-N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}thieno[2,3-d]pyrimidin-4-amine::6-Ethynylthieno[2,3-d]pyrimidine, 11	Epidermal growth factor receptor	Homo sapiens		 69					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27976	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27976&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218696	57560488							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51117	Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)C#C[C@H]3CCCN3)cc2Cl)c1 |r|	InChI=1S/C25H20ClFN4OS/c26-22-12-19(7-9-23(22)32-14-16-3-1-4-17(27)11-16)31-24-21-13-20(33-25(21)30-15-29-24)8-6-18-5-2-10-28-18/h1,3-4,7,9,11-13,15,18,28H,2,5,10,14H2,(H,29,30,31)	TWIUFSQIKGYUBP-UHFFFAOYSA-N	27977	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{2-[(2R)-pyrrolidin-2-yl]ethynyl}thieno[2,3-d]pyrimidin-4-amine::6-Ethynylthieno[2,3-d]pyrimidine, 12	Epidermal growth factor receptor	Homo sapiens		 109					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27977	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27977&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218697	57560489							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51118	Nc1cnc(cn1)C#Cc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2s1	InChI=1S/C25H16ClFN6OS/c26-21-9-17(5-7-22(21)34-13-15-2-1-3-16(27)8-15)33-24-20-10-19(35-25(20)32-14-31-24)6-4-18-11-30-23(28)12-29-18/h1-3,5,7-12,14H,13H2,(H2,28,30)(H,31,32,33)	WLEIXJUVTKOBDP-UHFFFAOYSA-N	27978	5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[2,3-d]pyrimidin-6-yl]ethynyl}pyrazin-2-amine::6-Ethynylthieno[2,3-d]pyrimidine, 13	Epidermal growth factor receptor	Homo sapiens		 372					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27978	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27978&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11260603	57560490							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51119	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::cid_208908::CHEMBL554::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::LAPATINIB DITOSYLATE::GW572016::Tykerb::US9730934, Lapatinib ditosylate::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib	Epidermal growth factor receptor	Homo sapiens		 11					7.5000	23.00 C	Curated from the literature by BindingDB	10.1073/pnas.0708281105	10.7270/Q27S7M35	18287036	aid1798859		Wood, ER; Shewchuk, LM; Ellis, B; Brignola, P; Brashear, RL; Caferro, TR; Dickerson, SH; Dickson, HD; Donaldson, KH; Gaul, M; Griffin, RJ; Hassell, AM; Keith, B; Mullin, R; Petrov, KG; Reno, MJ; Rusnak, DW; Tadepalli, SM; Ulrich, JC; Wagner, CD; Vanderwall, DE; Waterson, AG; Williams, JD; White, WL; Uehling, DE	2/26/2008	4/5/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			208908	8035064		CHEMBL554	DB01259				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51749	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cc2Cl)c1 |r|	InChI=1S/C30H27ClFN5O4S/c31-25-14-22(5-7-27(25)40-17-19-2-1-3-20(32)12-19)36-29-28-26(34-18-35-29)15-24(42-28)6-4-21-13-23(16-33-21)41-30(38)37-8-10-39-11-9-37/h1-3,5,7,12,14-15,18,21,23,33H,8-11,13,16-17H2,(H,34,35,36)	NKOJMDRKLJSOJR-UHFFFAOYSA-N	28489	BMCL1921 Compound 6h::(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15a	Epidermal growth factor receptor	Homo sapiens		 80					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28489&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11284937	58097677							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51750	Clc1cc(Nc2ncnc3cc(sc23)C#C[C@@H]2C[C@H](CN2)OC(=O)N2CCOCC2)ccc1OCc1ccccn1 |r|	InChI=1S/C29H27ClN6O4S/c30-24-14-20(5-7-26(24)39-17-21-3-1-2-8-31-21)35-28-27-25(33-18-34-28)15-23(41-27)6-4-19-13-22(16-32-19)40-29(37)36-9-11-38-12-10-36/h1-3,5,7-8,14-15,18-19,22,32H,9-13,16-17H2,(H,33,34,35)	WFTNHECJAZFTJB-UHFFFAOYSA-N	28490	(3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15b	Epidermal growth factor receptor	Homo sapiens		 50					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28490&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263246	58097678							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51751	Clc1cc(Nc2ncnc3cc(sc23)C#C[C@@H]2C[C@H](CN2)OC(=O)N2CCOCC2)ccc1OCc1cscn1 |r|	InChI=1S/C27H25ClN6O4S2/c28-22-10-18(2-4-24(22)37-13-19-14-39-16-32-19)33-26-25-23(30-15-31-26)11-21(40-25)3-1-17-9-20(12-29-17)38-27(35)34-5-7-36-8-6-34/h2,4,10-11,14-17,20,29H,5-9,12-13H2,(H,30,31,33)	LYJHHXBOBVEKHY-UHFFFAOYSA-N	28491	(3R,5S)-5-[2-(4-{[3-chloro-4-(1,3-thiazol-4-ylmethoxy)phenyl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15c	Epidermal growth factor receptor	Homo sapiens		 120					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28491&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263247	58097679							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51752	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cn2)c1 |r|	InChI=1S/C29H27FN6O4S/c30-20-3-1-2-19(12-20)17-39-26-7-5-22(15-32-26)35-28-27-25(33-18-34-28)14-24(41-27)6-4-21-13-23(16-31-21)40-29(37)36-8-10-38-11-9-36/h1-3,5,7,12,14-15,18,21,23,31H,8-11,13,16-17H2,(H,33,34,35)	NWRYHCNPTDKBAI-UHFFFAOYSA-N	28492	(3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyridin-3-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15d	Epidermal growth factor receptor	Homo sapiens		 2600					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28492	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28492&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263248	58097680							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51753	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc4c(Oc5ccccn5)cccc4c3)c2s1)N1CCOCC1 |r|	InChI=1S/C32H28N6O4S/c39-32(38-12-14-40-15-13-38)41-24-17-22(34-19-24)7-9-25-18-27-30(43-25)31(36-20-35-27)37-23-8-10-26-21(16-23)4-3-5-28(26)42-29-6-1-2-11-33-29/h1-6,8,10-11,16,18,20,22,24,34H,12-15,17,19H2,(H,35,36,37)	IUDNEWGUEHBBOQ-UHFFFAOYSA-N	28493	(3R,5S)-5-[2-(4-{[5-(pyridin-2-yloxy)naphthalen-2-yl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15e	Epidermal growth factor receptor	Homo sapiens		 1050					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28493&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263249	58097681							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51754	Clc1cc(Nc2ncnc3cc(sc23)C#C[C@@H]2C[C@H](CN2)OC(=O)N2CCOCC2)ccc1Oc1ccccn1 |r|	InChI=1S/C28H25ClN6O4S/c29-22-14-19(5-7-24(22)39-25-3-1-2-8-30-25)34-27-26-23(32-17-33-27)15-21(40-26)6-4-18-13-20(16-31-18)38-28(36)35-9-11-37-12-10-35/h1-3,5,7-8,14-15,17-18,20,31H,9-13,16H2,(H,32,33,34)	LJKWMYHCZOUEOQ-UHFFFAOYSA-N	28494	(3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-yloxy)phenyl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15f	Epidermal growth factor receptor	Homo sapiens		 190					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28494&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263250	58097682							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51755	Cc1cc(Oc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cc2Cl)no1 |r|	InChI=1S/C27H25ClN6O5S/c1-16-10-24(33-39-16)38-23-5-3-18(12-21(23)28)32-26-25-22(30-15-31-26)13-20(40-25)4-2-17-11-19(14-29-17)37-27(35)34-6-8-36-9-7-34/h3,5,10,12-13,15,17,19,29H,6-9,11,14H2,1H3,(H,30,31,32)	SBYLTLVZZWSDEP-UHFFFAOYSA-N	28495	(3R,5S)-5-{2-[4-({3-chloro-4-[(5-methyl-1,2-oxazol-3-yl)oxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15g	Epidermal growth factor receptor	Homo sapiens		 400					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28495&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263251	58097683							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51756	Fc1ccc2nccc(Oc3ccc(Nc4ncnc5cc(sc45)C#C[C@@H]4C[C@H](CN4)OC(=O)N4CCOCC4)cc3Cl)c2c1 |r|	InChI=1S/C32H26ClFN6O4S/c33-25-15-21(3-6-29(25)44-28-7-8-35-26-5-1-19(34)13-24(26)28)39-31-30-27(37-18-38-31)16-23(45-30)4-2-20-14-22(17-36-20)43-32(41)40-9-11-42-12-10-40/h1,3,5-8,13,15-16,18,20,22,36H,9-12,14,17H2,(H,37,38,39)	FCKGEOQXHWZJHO-UHFFFAOYSA-N	28496	(3R,5S)-5-{2-[4-({3-chloro-4-[(6-fluoroquinolin-4-yl)oxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15h	Epidermal growth factor receptor	Homo sapiens		 280					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28496&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263252	58097684							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51757	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(NCc3cccc(Oc4ccccc4)c3)c2s1)N1CCOCC1 |r|	InChI=1S/C30H29N5O4S/c36-30(35-11-13-37-14-12-35)39-25-16-22(31-19-25)9-10-26-17-27-28(40-26)29(34-20-33-27)32-18-21-5-4-8-24(15-21)38-23-6-2-1-3-7-23/h1-8,15,17,20,22,25,31H,11-14,16,18-19H2,(H,32,33,34)	BGHXZIFCCVTXMJ-UHFFFAOYSA-N	28497	(3R,5S)-5-[2-(4-{[(3-phenoxyphenyl)methyl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15i	Epidermal growth factor receptor	Homo sapiens		 180					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28497&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263253	58097685							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51758	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(Cc4ccccc4)cc3)c2s1)N1CCOCC1 |r|	InChI=1S/C30H29N5O3S/c36-30(35-12-14-37-15-13-35)38-25-17-24(31-19-25)10-11-26-18-27-28(39-26)29(33-20-32-27)34-23-8-6-22(7-9-23)16-21-4-2-1-3-5-21/h1-9,18,20,24-25,31H,12-17,19H2,(H,32,33,34)	QAOIGWCWWITZTC-UHFFFAOYSA-N	28498	(3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-d]pyrimidin-6-yl}ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15j	Epidermal growth factor receptor	Homo sapiens		 240					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28498&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263254	58097686							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51759	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(Sc4ccccn4)cc3)c2s1)N1CCOCC1 |r|	InChI=1S/C28H26N6O3S2/c35-28(34-11-13-36-14-12-34)37-21-15-20(30-17-21)6-9-23-16-24-26(39-23)27(32-18-31-24)33-19-4-7-22(8-5-19)38-25-3-1-2-10-29-25/h1-5,7-8,10,16,18,20-21,30H,11-15,17H2,(H,31,32,33)	WCDMWNJUWOHGEY-UHFFFAOYSA-N	28499	(3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15k	Epidermal growth factor receptor	Homo sapiens		 1650					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28499&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263255	58097687							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51760	Fc1cccc(Sc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cc2Cl)c1 |r|	InChI=1S/C29H25ClFN5O3S2/c30-24-14-20(5-7-26(24)40-22-3-1-2-18(31)12-22)35-28-27-25(33-17-34-28)15-23(41-27)6-4-19-13-21(16-32-19)39-29(37)36-8-10-38-11-9-36/h1-3,5,7,12,14-15,17,19,21,32H,8-11,13,16H2,(H,33,34,35)	RJZPDKUWHMCJNM-UHFFFAOYSA-N	28500	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulfanyl]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15l	Epidermal growth factor receptor	Homo sapiens		 630					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28500&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263256	58097688							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51761	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2s1)N1CCOCC1 |r|	InChI=1S/C31H29N7O3S/c39-31(37-10-12-40-13-11-37)41-25-15-23(32-18-25)6-8-26-16-27-29(42-26)30(34-20-33-27)36-24-7-9-28-22(14-24)17-35-38(28)19-21-4-2-1-3-5-21/h1-5,7,9,14,16-17,20,23,25,32H,10-13,15,18-19H2,(H,33,34,36)	SDHRCQGCPUPURT-UHFFFAOYSA-N	28501	(3R,5S)-5-(2-{4-[(1-benzyl-1H-indazol-5-yl)amino]thieno[3,2-d]pyrimidin-6-yl}ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15m	Epidermal growth factor receptor	Homo sapiens		 80					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28501&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263257	58097689							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51762	Fc1cccc(Cn2ncc3cc(Nc4ncnc5cc(sc45)C#C[C@@H]4C[C@H](CN4)OC(=O)N4CCOCC4)ccc23)c1 |r|	InChI=1S/C31H28FN7O3S/c32-22-3-1-2-20(12-22)18-39-28-7-5-24(13-21(28)16-36-39)37-30-29-27(34-19-35-30)15-26(43-29)6-4-23-14-25(17-33-23)42-31(40)38-8-10-41-11-9-38/h1-3,5,7,12-13,15-16,19,23,25,33H,8-11,14,17-18H2,(H,34,35,37)	LRLNQABHVFTDEO-UHFFFAOYSA-N	28502	(3R,5S)-5-{2-[4-({1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15n	Epidermal growth factor receptor	Homo sapiens		 30					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28502&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263258	58097690							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51763	Fc1ccc(F)c(Cn2ncc3cc(Nc4ncnc5cc(sc45)C#C[C@@H]4C[C@H](CN4)OC(=O)N4CCOCC4)ccc23)c1 |r|	InChI=1S/C31H27F2N7O3S/c32-21-1-5-26(33)20(11-21)17-40-28-6-3-23(12-19(28)15-37-40)38-30-29-27(35-18-36-30)14-25(44-29)4-2-22-13-24(16-34-22)43-31(41)39-7-9-42-10-8-39/h1,3,5-6,11-12,14-15,18,22,24,34H,7-10,13,16-17H2,(H,35,36,38)	HRADRJGXRLBLGD-UHFFFAOYSA-N	28503	(3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1H-indazol-5-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15o	Epidermal growth factor receptor	Homo sapiens		 33					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28503&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263259	58097691							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51764	CC(c1cccc(F)c1)n1ncc2cc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)ccc12 |r|	InChI=1S/C32H30FN7O3S/c1-20(21-3-2-4-23(33)13-21)40-29-8-6-25(14-22(29)17-37-40)38-31-30-28(35-19-36-31)16-27(44-30)7-5-24-15-26(18-34-24)43-32(41)39-9-11-42-12-10-39/h2-4,6,8,13-14,16-17,19-20,24,26,34H,9-12,15,18H2,1H3,(H,35,36,38)	OMNUQQMMTVDCHE-UHFFFAOYSA-N	28504	(3R,5S)-5-{2-[4-({1-[1-(3-fluorophenyl)ethyl]-1H-indazol-5-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15p	Epidermal growth factor receptor	Homo sapiens		 120					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28504&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263260	58097692							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51765	Fc1cccc(c1)S(=O)(=O)n1ncc2cc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)ccc12 |r|	InChI=1S/C30H26FN7O5S2/c31-20-2-1-3-25(13-20)45(40,41)38-27-7-5-22(12-19(27)16-35-38)36-29-28-26(33-18-34-29)15-24(44-28)6-4-21-14-23(17-32-21)43-30(39)37-8-10-42-11-9-37/h1-3,5,7,12-13,15-16,18,21,23,32H,8-11,14,17H2,(H,33,34,36)	DNGKMKTZKCGWMO-UHFFFAOYSA-N	28505	(3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H-indazol-5-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15q	Epidermal growth factor receptor	Homo sapiens		 230					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28505&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263261	58097693							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51766	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc4n(ccc4c3)S(=O)(=O)c3cccs3)c2s1)N1CCOCC1 |r|	InChI=1S/C29H26N6O5S3/c36-29(34-9-11-39-12-10-34)40-22-15-20(30-17-22)3-5-23-16-24-27(42-23)28(32-18-31-24)33-21-4-6-25-19(14-21)7-8-35(25)43(37,38)26-2-1-13-41-26/h1-2,4,6-8,13-14,16,18,20,22,30H,9-12,15,17H2,(H,31,32,33)	ZFBVZPNEZMXKOV-UHFFFAOYSA-N	28506	(3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indol-5-yl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15r	Epidermal growth factor receptor	Homo sapiens		 150					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28506&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263262	58097694							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51767	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc4n(Cc5ccccc5)ccc4c3)c2s1)N1CCOCC1 |r|	InChI=1S/C32H30N6O3S/c39-32(37-12-14-40-15-13-37)41-26-17-24(33-19-26)6-8-27-18-28-30(42-27)31(35-21-34-28)36-25-7-9-29-23(16-25)10-11-38(29)20-22-4-2-1-3-5-22/h1-5,7,9-11,16,18,21,24,26,33H,12-15,17,19-20H2,(H,34,35,36)	JKMMLNQHOCOLSR-UHFFFAOYSA-N	28507	(3R,5S)-5-(2-{4-[(1-benzyl-1H-indol-5-yl)amino]thieno[3,2-d]pyrimidin-6-yl}ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15s	Epidermal growth factor receptor	Homo sapiens		 90					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28507&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263263	58097695							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51768	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc4n(CCc5ccccc5)ccc4c3)c2s1)N1CCOCC1 |r|	InChI=1S/C33H32N6O3S/c40-33(39-14-16-41-17-15-39)42-27-19-25(34-21-27)6-8-28-20-29-31(43-28)32(36-22-35-29)37-26-7-9-30-24(18-26)11-13-38(30)12-10-23-4-2-1-3-5-23/h1-5,7,9,11,13,18,20,22,25,27,34H,10,12,14-17,19,21H2,(H,35,36,37)	JOAKGRBKTPJXHB-UHFFFAOYSA-N	28508	(3R,5S)-5-[2-(4-{[1-(2-phenylethyl)-1H-indol-5-yl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15t	Epidermal growth factor receptor	Homo sapiens		 3160					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28508&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263264	58097696							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51769	O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc4n(Cc5cscn5)ccc4c3)c2s1)N1CCOCC1 |r|	InChI=1S/C29H27N7O3S2/c37-29(35-7-9-38-10-8-35)39-23-12-20(30-14-23)1-3-24-13-25-27(41-24)28(32-17-31-25)34-21-2-4-26-19(11-21)5-6-36(26)15-22-16-40-18-33-22/h2,4-6,11,13,16-18,20,23,30H,7-10,12,14-15H2,(H,31,32,34)	OMQOMUUJUACRFX-UHFFFAOYSA-N	28509	(3R,5S)-5-[2-(4-{[1-(1,3-thiazol-4-ylmethyl)-1H-indol-5-yl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15u	Epidermal growth factor receptor	Homo sapiens		 680					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28509&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263265	58097697							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51770	Fc1cn(Cc2ccccc2)c2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cc12 |r|	InChI=1S/C32H29FN6O3S/c33-27-19-39(18-21-4-2-1-3-5-21)29-9-7-23(15-26(27)29)37-31-30-28(35-20-36-31)16-25(43-30)8-6-22-14-24(17-34-22)42-32(40)38-10-12-41-13-11-38/h1-5,7,9,15-16,19-20,22,24,34H,10-14,17-18H2,(H,35,36,37)	VURXMUNOWCBINZ-UHFFFAOYSA-N	28510	(3R,5S)-5-(2-{4-[(1-benzyl-3-fluoro-1H-indol-5-yl)amino]thieno[3,2-d]pyrimidin-6-yl}ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15v	Epidermal growth factor receptor	Homo sapiens		 240					7.5000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.01.080	10.7270/Q2SN078S	19208477	aid1798897		Waterson, AG; Petrov, KG; Hornberger, KR; Hubbard, RD; Sammond, DM; Smith, SC; Dickson, HD; Caferro, TR; Hinkle, KW; Stevens, KL; Dickerson, SH; Rusnak, DW; Spehar, GM; Wood, ER; Griffin, RJ; Uehling, DE	3/1/2009	4/20/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28510&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263266	58097698							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51793	NC(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C26H21ClFN5O3S/c27-21-10-18(5-7-23(21)35-13-15-2-1-3-16(28)8-15)33-25-24-22(31-14-32-25)11-20(37-24)6-4-17-9-19(12-30-17)36-26(29)34/h1-3,5,7-8,10-11,14,17,19,30H,9,12-13H2,(H2,29,34)(H,31,32,33)	QAIGLWIBJKERDJ-UHFFFAOYSA-N	28511	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl carbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6a	Epidermal growth factor receptor	Homo sapiens		 40					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28511&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263267	58097699							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51794	CNC(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C27H23ClFN5O3S/c1-30-27(35)37-20-10-18(31-13-20)5-7-21-12-23-25(38-21)26(33-15-32-23)34-19-6-8-24(22(28)11-19)36-14-16-3-2-4-17(29)9-16/h2-4,6,8-9,11-12,15,18,20,31H,10,13-14H2,1H3,(H,30,35)(H,32,33,34)	XNBMKLASHVMECR-UHFFFAOYSA-N	28512	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N-methylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6b	Epidermal growth factor receptor	Homo sapiens		 50					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28512&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263268	58097700							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51795	CCNC(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-2-31-28(36)38-21-11-19(32-14-21)6-8-22-13-24-26(39-22)27(34-16-33-24)35-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,32H,2,11,14-15H2,1H3,(H,31,36)(H,33,34,35)	IYINYGZMZPUBOK-UHFFFAOYSA-N	28513	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N-ethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6c	Epidermal growth factor receptor	Homo sapiens		 32					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28513&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11307581	58097701							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51796	CN(C)C(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-35(2)28(36)38-21-11-19(31-14-21)6-8-22-13-24-26(39-22)27(33-16-32-24)34-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,31H,11,14-15H2,1-2H3,(H,32,33,34)	YEIAMNOHYKXSFB-UHFFFAOYSA-N	28514	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N,N-dimethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6d	Epidermal growth factor receptor	Homo sapiens		 28					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28514&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11273032	58097702							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51797	CCN(CC)C(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C30H29ClFN5O3S/c1-3-37(4-2)30(38)40-23-13-21(33-16-23)8-10-24-15-26-28(41-24)29(35-18-34-26)36-22-9-11-27(25(31)14-22)39-17-19-6-5-7-20(32)12-19/h5-7,9,11-12,14-15,18,21,23,33H,3-4,13,16-17H2,1-2H3,(H,34,35,36)	GWKMIVYJIGCSBU-UHFFFAOYSA-N	28515	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N,N-diethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6e	Epidermal growth factor receptor	Homo sapiens		 63					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28515&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11490270	58097703							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51798	CCN(C)C(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C29H27ClFN5O3S/c1-3-36(2)29(37)39-22-12-20(32-15-22)7-9-23-14-25-27(40-23)28(34-17-33-25)35-21-8-10-26(24(30)13-21)38-16-18-5-4-6-19(31)11-18/h4-6,8,10-11,13-14,17,20,22,32H,3,12,15-16H2,1-2H3,(H,33,34,35)	OQGBHQFXDSBPBX-UHFFFAOYSA-N	28516	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N-ethyl-N-methylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6f	Epidermal growth factor receptor	Homo sapiens		 50					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28516&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263269	58097704							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51799	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCCC3)cc2Cl)c1 |r|	InChI=1S/C30H27ClFN5O3S/c31-25-14-22(7-9-27(25)39-17-19-4-3-5-20(32)12-19)36-29-28-26(34-18-35-29)15-24(41-28)8-6-21-13-23(16-33-21)40-30(38)37-10-1-2-11-37/h3-5,7,9,12,14-15,18,21,23,33H,1-2,10-11,13,16-17H2,(H,34,35,36)	UWADRORTXGMUIP-UHFFFAOYSA-N	28517	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl pyrrolidine-1-carboxylate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6g	Epidermal growth factor receptor	Homo sapiens		 99					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28517	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28517&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263270	58097705							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51800	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cc2Cl)c1 |r|	InChI=1S/C30H27ClFN5O4S/c31-25-14-22(5-7-27(25)40-17-19-2-1-3-20(32)12-19)36-29-28-26(34-18-35-29)15-24(42-28)6-4-21-13-23(16-33-21)41-30(38)37-8-10-39-11-9-37/h1-3,5,7,12,14-15,18,21,23,33H,8-11,13,16-17H2,(H,34,35,36)	NKOJMDRKLJSOJR-UHFFFAOYSA-N	28489	BMCL1921 Compound 6h::(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15a	Epidermal growth factor receptor	Homo sapiens		 65					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28489&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11284937	58097677							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51801	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCNCC3)cc2Cl)c1 |r|	InChI=1S/C30H28ClFN6O3S/c31-25-14-22(5-7-27(25)40-17-19-2-1-3-20(32)12-19)37-29-28-26(35-18-36-29)15-24(42-28)6-4-21-13-23(16-34-21)41-30(39)38-10-8-33-9-11-38/h1-3,5,7,12,14-15,18,21,23,33-34H,8-11,13,16-17H2,(H,35,36,37)	QHVIPDJZOQGJIA-UHFFFAOYSA-N	28518	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl piperazine-1-carboxylate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6i	Epidermal growth factor receptor	Homo sapiens		 63					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28518&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263271	58097706							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51802	CS(=O)(=O)CCNC(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C29H27ClFN5O5S2/c1-43(38,39)10-9-32-29(37)41-22-12-20(33-15-22)5-7-23-14-25-27(42-23)28(35-17-34-25)36-21-6-8-26(24(30)13-21)40-16-18-3-2-4-19(31)11-18/h2-4,6,8,11,13-14,17,20,22,33H,9-10,12,15-16H2,1H3,(H,32,37)(H,34,35,36)	NWDMCJXGXJGDKM-UHFFFAOYSA-N	28519	(3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N-(2-methanesulfonylethyl)carbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 6j	Epidermal growth factor receptor	Homo sapiens		 40					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28519&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263272	58097707							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51803	CCNC(=O)O[C@@H]1CN[C@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-2-31-28(36)38-21-11-19(32-14-21)6-8-22-13-24-26(39-22)27(34-16-33-24)35-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,32H,2,11,14-15H2,1H3,(H,31,36)(H,33,34,35)	IYINYGZMZPUBOK-UHFFFAOYSA-N	28520	(3S,5R)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N-ethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 14	Epidermal growth factor receptor	Homo sapiens		 50					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28520&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263273	58097708							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51804	CN(C)C(=O)O[C@@H]1CN[C@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-35(2)28(36)38-21-11-19(31-14-21)6-8-22-13-24-26(39-22)27(33-16-32-24)34-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,31H,11,14-15H2,1-2H3,(H,32,33,34)	YEIAMNOHYKXSFB-UHFFFAOYSA-N	28521	(3S,5R)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N,N-dimethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 15	Epidermal growth factor receptor	Homo sapiens		 40					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28521	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28521&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263274	58097709							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51805	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@H]3C[C@@H](CN3)OC(=O)N3CCOCC3)cc2Cl)c1 |r|	InChI=1S/C30H27ClFN5O4S/c31-25-14-22(5-7-27(25)40-17-19-2-1-3-20(32)12-19)36-29-28-26(34-18-35-29)15-24(42-28)6-4-21-13-23(16-33-21)41-30(38)37-8-10-39-11-9-37/h1-3,5,7,12,14-15,18,21,23,33H,8-11,13,16-17H2,(H,34,35,36)	NKOJMDRKLJSOJR-UHFFFAOYSA-N	28522	(3S,5R)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 16	Epidermal growth factor receptor	Homo sapiens		 40					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28522&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263275	58097710							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51806	CCNC(=O)O[C@@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-2-31-28(36)38-21-11-19(32-14-21)6-8-22-13-24-26(39-22)27(34-16-33-24)35-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,32H,2,11,14-15H2,1H3,(H,31,36)(H,33,34,35)	IYINYGZMZPUBOK-UHFFFAOYSA-N	28523	(3S,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N-ethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 17	Epidermal growth factor receptor	Homo sapiens		 125					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28523&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263276	58097711							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51807	CN(C)C(=O)O[C@@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-35(2)28(36)38-21-11-19(31-14-21)6-8-22-13-24-26(39-22)27(33-16-32-24)34-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,31H,11,14-15H2,1-2H3,(H,32,33,34)	YEIAMNOHYKXSFB-UHFFFAOYSA-N	28524	(3S,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N,N-dimethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 18	Epidermal growth factor receptor	Homo sapiens		 79					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28524&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263277	58097712							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51808	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@@H](CN3)OC(=O)N3CCOCC3)cc2Cl)c1 |r|	InChI=1S/C30H27ClFN5O4S/c31-25-14-22(5-7-27(25)40-17-19-2-1-3-20(32)12-19)36-29-28-26(34-18-35-29)15-24(42-28)6-4-21-13-23(16-33-21)41-30(38)37-8-10-39-11-9-37/h1-3,5,7,12,14-15,18,21,23,33H,8-11,13,16-17H2,(H,34,35,36)	NKOJMDRKLJSOJR-UHFFFAOYSA-N	28525	(3S,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 19	Epidermal growth factor receptor	Homo sapiens		 79					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28525&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263278	58097713							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51809	CCNC(=O)O[C@H]1CN[C@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-2-31-28(36)38-21-11-19(32-14-21)6-8-22-13-24-26(39-22)27(34-16-33-24)35-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,32H,2,11,14-15H2,1H3,(H,31,36)(H,33,34,35)	IYINYGZMZPUBOK-UHFFFAOYSA-N	28526	(3R,5R)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N-ethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 20	Epidermal growth factor receptor	Homo sapiens		 32					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28526&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263279	58097714							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51810	CN(C)C(=O)O[C@H]1CN[C@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 |r|	InChI=1S/C28H25ClFN5O3S/c1-35(2)28(36)38-21-11-19(31-14-21)6-8-22-13-24-26(39-22)27(33-16-32-24)34-20-7-9-25(23(29)12-20)37-15-17-4-3-5-18(30)10-17/h3-5,7,9-10,12-13,16,19,21,31H,11,14-15H2,1-2H3,(H,32,33,34)	YEIAMNOHYKXSFB-UHFFFAOYSA-N	28527	(3R,5R)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl N,N-dimethylcarbamate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 21	Epidermal growth factor receptor	Homo sapiens		 79					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28527&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263280	58097715							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51811	Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cc2Cl)c1 |r|	InChI=1S/C30H27ClFN5O4S/c31-25-14-22(5-7-27(25)40-17-19-2-1-3-20(32)12-19)36-29-28-26(34-18-35-29)15-24(42-28)6-4-21-13-23(16-33-21)41-30(38)37-8-10-39-11-9-37/h1-3,5,7,12,14-15,18,21,23,33H,8-11,13,16-17H2,(H,34,35,36)	NKOJMDRKLJSOJR-UHFFFAOYSA-N	28528	(3R,5R)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine, 22	Epidermal growth factor receptor	Homo sapiens		 50					7.5000	23.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.11.023	10.7270/Q2NV9GKZ	19028424	aid1798900		Stevens, KL; Alligood, KJ; Alberti, JG; Caferro, TR; Chamberlain, SD; Dickerson, SH; Dickson, HD; Emerson, HK; Griffin, RJ; Hubbard, RD; Keith, BR; Mullin, RJ; Petrov, KG; Gerding, RM; Reno, MJ; Rheault, TR; Rusnak, DW; Sammond, DM; Smith, SC; Uehling, DE; Waterson, AG; Wood, ER	1/1/2009	4/21/2009	Gsk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28528&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25263281	58097716							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59721	C/C(=C\c1coc2c1c(nc(n2)N)N)/c3ccccc3OC	InChI=1S/C16H16N4O2/c1-9(11-5-3-4-6-12(11)21-2)7-10-8-22-15-13(10)14(17)19-16(18)20-15/h3-8H,1-2H3,(H4,17,18,19,20)	JXICVPBZQSPDOK-UHFFFAOYSA-N	33394	E-isomer::2,4-diaminofuro[2,3-d]pyrimidine, 1a	Epidermal growth factor receptor	Homo sapiens		>50000					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33394	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33394&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	D09		6477203	85267012							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59722	C/C(=C/c1coc2c1c(nc(n2)N)N)/c3ccccc3OC	InChI=1S/C16H16N4O2/c1-9(11-5-3-4-6-12(11)21-2)7-10-8-22-15-13(10)14(17)19-16(18)20-15/h3-8H,1-2H3,(H4,17,18,19,20)	JXICVPBZQSPDOK-UHFFFAOYSA-N	33395	Z-isomer::2,4-diaminofuro[2,3-d]pyrimidine, 1b	Epidermal growth factor receptor	Homo sapiens		>200000					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33395&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	51P	3GYF	11687971	85267013							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59723	CCC\C(=C\c1coc2nc(N)nc(N)c12)c1ccccc1OC	InChI=1S/C18H20N4O2/c1-3-6-11(13-7-4-5-8-14(13)23-2)9-12-10-24-17-15(12)16(19)21-18(20)22-17/h4-5,7-10H,3,6H2,1-2H3,(H4,19,20,21,22)	QRIUQJQGVYRORZ-UHFFFAOYSA-N	33396	E/Z ratio=2:1::2,4-diaminofuro[2,3-d]pyrimidine, 2	Epidermal growth factor receptor	Homo sapiens		 160300					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33396&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246319	85267014							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59724	CC(C)/C(=C/c1coc2c1c(nc(n2)N)N)/c3ccccc3OC	InChI=1S/C18H20N4O2/c1-10(2)13(12-6-4-5-7-14(12)23-3)8-11-9-24-17-15(11)16(19)21-18(20)22-17/h4-10H,1-3H3,(H4,19,20,21,22)	ZBHMLBFDTQKTKI-UHFFFAOYSA-N	33397	E/Z ratio=3:1::2,4-diaminofuro[2,3-d]pyrimidine, 3	Epidermal growth factor receptor	Homo sapiens		 111400					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33397&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	D2B	3NXO	44246320	85267015							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59725	COc1ccccc1\C(=C/c1coc2nc(N)nc(N)c12)C1CC1	InChI=1S/C18H18N4O2/c1-23-14-5-3-2-4-12(14)13(10-6-7-10)8-11-9-24-17-15(11)16(19)21-18(20)22-17/h2-5,8-10H,6-7H2,1H3,(H4,19,20,21,22)	PUOLMVSSUQSKAQ-UHFFFAOYSA-N	33398	E/Z ratio=2:1::2,4-diaminofuro[2,3-d]pyrimidine, 4	Epidermal growth factor receptor	Homo sapiens		>200000					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33398&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246321	85267016							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59726	CCCC\C(=C\c1coc2nc(N)nc(N)c12)c1ccccc1OC	InChI=1S/C19H22N4O2/c1-3-4-7-12(14-8-5-6-9-15(14)24-2)10-13-11-25-18-16(13)17(20)22-19(21)23-18/h5-6,8-11H,3-4,7H2,1-2H3,(H4,20,21,22,23)	OJEFVGFDNJBOHB-UHFFFAOYSA-N	33399	E/Z ratio=3:2::2,4-diaminofuro[2,3-d]pyrimidine, 5	Epidermal growth factor receptor	Homo sapiens		 529300					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33399	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33399&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246322	85267017							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59727	COc1ccccc1\C(CC(C)C)=C/c1coc2nc(N)nc(N)c12	InChI=1S/C19H22N4O2/c1-11(2)8-12(14-6-4-5-7-15(14)24-3)9-13-10-25-18-16(13)17(20)22-19(21)23-18/h4-7,9-11H,8H2,1-3H3,(H4,20,21,22,23)	GSEWOBPWXZKJLQ-UHFFFAOYSA-N	33400	E/Z ratio=2:1::2,4-diaminofuro[2,3-d]pyrimidine, 6	Epidermal growth factor receptor	Homo sapiens		>200000					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33400&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246323	85267018							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59728	CCC(C)C(=C\c1coc2nc(N)nc(N)c12)\c1ccccc1OC	InChI=1S/C19H22N4O2/c1-4-11(2)14(13-7-5-6-8-15(13)24-3)9-12-10-25-18-16(12)17(20)22-19(21)23-18/h5-11H,4H2,1-3H3,(H4,20,21,22,23)	GGNUJBNONVTLHE-UHFFFAOYSA-N	33401	E/Z ratio=3:2::2,4-diaminofuro[2,3-d]pyrimidine, 7	Epidermal growth factor receptor	Homo sapiens		>200000					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246324	85267019							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59729	CCCC(Cc1coc2nc(N)nc(N)c12)c1ccccc1OC	InChI=1S/C18H22N4O2/c1-3-6-11(13-7-4-5-8-14(13)23-2)9-12-10-24-17-15(12)16(19)21-18(20)22-17/h4-5,7-8,10-11H,3,6,9H2,1-2H3,(H4,19,20,21,22)	YGUDCFAGRCRLHT-UHFFFAOYSA-N	33402	2,4-diaminofuro[2,3-d]pyrimidine, 8	Epidermal growth factor receptor	Homo sapiens		 2200					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246325	85267020							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59730	COc1ccccc1C(Cc1coc2nc(N)nc(N)c12)C(C)C	InChI=1S/C18H22N4O2/c1-10(2)13(12-6-4-5-7-14(12)23-3)8-11-9-24-17-15(11)16(19)21-18(20)22-17/h4-7,9-10,13H,8H2,1-3H3,(H4,19,20,21,22)	AALMZTNNZVHOAS-UHFFFAOYSA-N	33403	2,4-diaminofuro[2,3-d]pyrimidine, 9	Epidermal growth factor receptor	Homo sapiens		 18200					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246326	85267021							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59731	COc1ccccc1C(Cc1coc2nc(N)nc(N)c12)C1CC1	InChI=1S/C18H20N4O2/c1-23-14-5-3-2-4-12(14)13(10-6-7-10)8-11-9-24-17-15(11)16(19)21-18(20)22-17/h2-5,9-10,13H,6-8H2,1H3,(H4,19,20,21,22)	ABOUXXMKTJTICI-UHFFFAOYSA-N	33404	2,4-diaminofuro[2,3-d]pyrimidine, 10	Epidermal growth factor receptor	Homo sapiens		 56500					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246327	85267022							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59732	CCCCC(Cc1coc2nc(N)nc(N)c12)c1ccccc1OC	InChI=1S/C19H24N4O2/c1-3-4-7-12(14-8-5-6-9-15(14)24-2)10-13-11-25-18-16(13)17(20)22-19(21)23-18/h5-6,8-9,11-12H,3-4,7,10H2,1-2H3,(H4,20,21,22,23)	VYSGSWCDOXJVNF-UHFFFAOYSA-N	33405	2,4-diaminofuro[2,3-d]pyrimidine, 11	Epidermal growth factor receptor	Homo sapiens		 13400					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246328	85267023							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59733	COc1ccccc1C(CC(C)C)Cc1coc2nc(N)nc(N)c12	InChI=1S/C19H24N4O2/c1-11(2)8-12(14-6-4-5-7-15(14)24-3)9-13-10-25-18-16(13)17(20)22-19(21)23-18/h4-7,10-12H,8-9H2,1-3H3,(H4,20,21,22,23)	FZTBMWCWXXNRIA-UHFFFAOYSA-N	33406	2,4-diaminofuro[2,3-d]pyrimidine, 12	Epidermal growth factor receptor	Homo sapiens		>500000					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33406	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33406&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246329	85267024							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59734	CCC(C)C(Cc1coc2nc(N)nc(N)c12)c1ccccc1OC	InChI=1S/C19H24N4O2/c1-4-11(2)14(13-7-5-6-8-15(13)24-3)9-12-10-25-18-16(12)17(20)22-19(21)23-18/h5-8,10-11,14H,4,9H2,1-3H3,(H4,20,21,22,23)	AYLKSELOGWVDPG-UHFFFAOYSA-N	33407	2,4-diaminofuro[2,3-d]pyrimidine, 13	Epidermal growth factor receptor	Homo sapiens		>200000					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44246330	85267025							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
59735	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	LSPANGZZENHZNJ-UHFFFAOYSA-N	3032	CHEMBL29197::N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::CHEMBL1204168::PD153035::US9422297, PD153035::US11111252, Compound PD153035::US11001595, Compound PD153035	Epidermal growth factor receptor	Homo sapiens		 200					7.4000	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2009.08.044	10.7270/Q2ZC8167	19748785	aid1799243		Gangjee, A; Li, W; Lin, L; Zeng, Y; Ihnat, M; Warnke, LA; Green, DW; Cody, V; Pace, J; Queener, SF	10/15/2009	11/6/2009	Duquesne University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3032&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4705	8032779		CHEMBL1204168CHEMBL29197					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65375	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	Epidermal growth factor receptor	Homo sapiens			 15						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65376	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	Epidermal growth factor receptor	Homo sapiens			 520						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65377	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	Epidermal growth factor receptor	Homo sapiens			 450						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65378	Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C	InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	MVCOAUNKQVWQHZ-UHFFFAOYSA-N	13533	1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(4-methylphenyl)-3-pyrazolyl]-3-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea::1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea::3-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-1-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB 796::BIRB-796::BIRB-796, 3::CHEMBL103667::D3RKN_73::Doramapimod::US11407771, Compound 43::US8933228, BIRB 796::US9187470, 43 (BIRB-796)::US9242960, BIRB 796::US9260410, BIRB796::cid_156422::diaryl urea compound 10	Epidermal growth factor receptor	Homo sapiens			 7000						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	B96	4JVG,1KV2,6GTT,5N66,4TWN,3NPC,3FZS	156422	46513934		CHEMBL103667	DB03044	5668		ZINC24044436	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65379	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.19						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65380	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 42						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65381	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 120						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65382	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.44						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65383	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 0.67						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65384	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 1.0						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65385	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 2.4						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65386	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 410						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65387	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 1300						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65388	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 2600						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65389	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 1700						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65390	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 370						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65391	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 9.5						PubChem		10.7270/Q2KD1W8R		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65392	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	Epidermal growth factor receptor	Homo sapiens			 1200						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65393	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	Epidermal growth factor receptor	Homo sapiens			 520						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65394	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	Epidermal growth factor receptor	Homo sapiens			 170						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65395	Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C	InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	MVCOAUNKQVWQHZ-UHFFFAOYSA-N	13533	1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(4-methylphenyl)-3-pyrazolyl]-3-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea::1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea::3-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-1-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB 796::BIRB-796::BIRB-796, 3::CHEMBL103667::D3RKN_73::Doramapimod::US11407771, Compound 43::US8933228, BIRB 796::US9187470, 43 (BIRB-796)::US9242960, BIRB 796::US9260410, BIRB796::cid_156422::diaryl urea compound 10	Epidermal growth factor receptor	Homo sapiens			 9100						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	B96	4JVG,1KV2,6GTT,5N66,4TWN,3NPC,3FZS	156422	46513934		CHEMBL103667	DB03044	5668		ZINC24044436	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65396	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.19						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65397	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 17						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65398	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 79						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65399	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.42						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65400	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 0.52						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65401	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 1.1						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65402	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 2.1						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65403	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 230						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65404	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 5300						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65405	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 1900						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65406	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 1300						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65407	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 1100						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65408	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 5.9						PubChem		10.7270/Q2FN14JD		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65409	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	Epidermal growth factor receptor	Homo sapiens			 1200						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65410	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	Epidermal growth factor receptor	Homo sapiens			 220						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65411	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	Epidermal growth factor receptor	Homo sapiens			 2900						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65412	Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C	InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	MVCOAUNKQVWQHZ-UHFFFAOYSA-N	13533	1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(4-methylphenyl)-3-pyrazolyl]-3-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea::1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea::3-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-1-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB 796::BIRB-796::BIRB-796, 3::CHEMBL103667::D3RKN_73::Doramapimod::US11407771, Compound 43::US8933228, BIRB 796::US9187470, 43 (BIRB-796)::US9242960, BIRB 796::US9260410, BIRB796::cid_156422::diaryl urea compound 10	Epidermal growth factor receptor	Homo sapiens			 5300						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	B96	4JVG,1KV2,6GTT,5N66,4TWN,3NPC,3FZS	156422	46513934		CHEMBL103667	DB03044	5668		ZINC24044436	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65413	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.17						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65414	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 720						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65415	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 110						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65416	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.24						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65417	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 0.52						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65418	CN1CCC([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl	InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12?,17-/m1/s1	BIIVYFLTOXDAOV-RGUGMKFQSA-N	31099	2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methyl-4-piperidinyl]-1-benzopyran-4-one::2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methyl-4-piperidyl]chromone::2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one::2-(2-chlorophenyl)-8-[(3S)-1-methyl-3-oxidanyl-piperidin-4-yl]-5,7-bis(oxidanyl)chromen-4-one::CHEMBL45741::Flavopiridol::cid_24867231	Epidermal growth factor receptor	Homo sapiens			 2300						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31099&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		3BLR,1C8K,1E1Y	24867231	252615340		CHEMBL45741				ZINC29416077	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65419	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 0.57						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65420	CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1	InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	KTUFNOKKBVMGRW-UHFFFAOYSA-N	13530	4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide::CHEMBL941::Gleevec::Imatinib::Imatinib, 21::N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide::STI-571::STI571::US10906896, Cpd imatinib::US11649218, Example Imatinib::US9255107, Imatinib::cid_5291::imatinib-CD3::med.21724, Compound 6	Epidermal growth factor receptor	Homo sapiens			 7600						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13530&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	STI	6HD6,6HD4,2HYY,4BKJ,2PL0,3GVU,6NPU,6NPV,6NPE,4CSV,3MS9,3MSS,4R7I,7N9G,2OIQ,1IEP,1XBB,3HEC,1T46,3FW1,3PYY,6VXH,6JOL,3K5V,5MQT,3OEZ,6KTN,1OPJ	5291	46513933	45783	CHEMBL941	DB00619	5687		ZINC19632618	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65421	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 2.2						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65422	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 260						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65423	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 620						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65424	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 2000						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65425	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 1700						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65426	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 96						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65427	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 12						PubChem		10.7270/Q29W0CTP		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65428	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	Epidermal growth factor receptor	Homo sapiens			 4500						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65429	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	Epidermal growth factor receptor	Homo sapiens			 550						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65430	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	Epidermal growth factor receptor	Homo sapiens			 8800						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65431	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.26						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65432	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 1800						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65433	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 320						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65434	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.27						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65435	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 0.47						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65436	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 0.57						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65437	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 3.9						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65438	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 410						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65439	OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2F)cc1	InChI=1S/C25H15ClF2N4O2/c26-15-6-9-17-18(10-15)23(21-19(27)2-1-3-20(21)28)29-11-14-12-30-25(32-22(14)17)31-16-7-4-13(5-8-16)24(33)34/h1-10,12H,11H2,(H,33,34)(H,30,31,32)	HHFBDROWDBDFBR-UHFFFAOYSA-N	31093	4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid::4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid::BDBM31832::CHEMBL259084::MLN-8054::cid_11712649	Epidermal growth factor receptor	Homo sapiens			 6400						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31093&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZZL	2X81,5IA1,2WTW,2WTV	11712649	252615338		CHEMBL259084		5696		ZINC18825334	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65440	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 1700						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65441	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 1400						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65442	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 1600						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65443	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 300						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65444	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 7.9						PubChem		10.7270/Q2639N34		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65445	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	Epidermal growth factor receptor	Homo sapiens			 2600						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65446	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	Epidermal growth factor receptor	Homo sapiens			 530						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65447	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	Epidermal growth factor receptor	Homo sapiens			 3500						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65448	Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C	InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	MVCOAUNKQVWQHZ-UHFFFAOYSA-N	13533	1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(4-methylphenyl)-3-pyrazolyl]-3-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea::1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea::3-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-1-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB 796::BIRB-796::BIRB-796, 3::CHEMBL103667::D3RKN_73::Doramapimod::US11407771, Compound 43::US8933228, BIRB 796::US9187470, 43 (BIRB-796)::US9242960, BIRB 796::US9260410, BIRB796::cid_156422::diaryl urea compound 10	Epidermal growth factor receptor	Homo sapiens			 6800						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	B96	4JVG,1KV2,6GTT,5N66,4TWN,3NPC,3FZS	156422	46513934		CHEMBL103667	DB03044	5668		ZINC24044436	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65449	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.26						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65450	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 560						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65451	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 160						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65452	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.23						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65453	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 0.35						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65454	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 0.52						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65455	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 3.5						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65456	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 470						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65457	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 1900						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65458	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 1100						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65459	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 1500						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65460	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 210						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65461	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 8.9						PubChem		10.7270/Q22B8WDV		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65462	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	Epidermal growth factor receptor	Homo sapiens			 3900						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65463	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	Epidermal growth factor receptor	Homo sapiens			 970						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65464	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	Epidermal growth factor receptor	Homo sapiens			 510						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65465	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.22						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65466	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 36						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65467	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 110						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65468	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.44						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65469	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 1.2						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65470	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 1.4						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65471	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 1.2						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65472	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 870						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65473	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 2800						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65474	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 2300						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65475	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 3200						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65476	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 600						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65477	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 11						PubChem		10.7270/Q2XP738C		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65877	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	Epidermal growth factor receptor	Homo sapiens			 1900						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65878	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.26						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65879	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 2000						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65880	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 130						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65881	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.38						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65882	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 0.48						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65883	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 0.54						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65884	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 8.6						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65885	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 330						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65886	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 7000						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65887	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 210						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65888	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 340						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65889	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 120						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
65890	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 4.8						PubChem		10.7270/Q2DJ5D15		aid1433		PubChem, PC	11/21/2008	4/22/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66421	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	Epidermal growth factor receptor	Homo sapiens			 5200						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66422	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens			 0.19						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66423	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	Epidermal growth factor receptor	Homo sapiens			 1000						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66424	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	Epidermal growth factor receptor	Homo sapiens			 330						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66425	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	Epidermal growth factor receptor	Homo sapiens			 0.33						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66426	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens			 1.6						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66427	CN1CCC([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl	InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12?,17-/m1/s1	BIIVYFLTOXDAOV-RGUGMKFQSA-N	31099	2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methyl-4-piperidinyl]-1-benzopyran-4-one::2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methyl-4-piperidyl]chromone::2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one::2-(2-chlorophenyl)-8-[(3S)-1-methyl-3-oxidanyl-piperidin-4-yl]-5,7-bis(oxidanyl)chromen-4-one::CHEMBL45741::Flavopiridol::cid_24867231	Epidermal growth factor receptor	Homo sapiens			 1400						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31099&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		3BLR,1C8K,1E1Y	24867231	252615340		CHEMBL45741				ZINC29416077	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66428	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens			 0.98						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66429	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens			 4.2						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66430	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	Epidermal growth factor receptor	Homo sapiens			 350						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66431	CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1	BMGQWWVMWDBQGC-PZFYLCKJSA-N	31094	PKC-412::cid_24202429	Epidermal growth factor receptor	Homo sapiens			 1800						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31094&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24202429	242052840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66432	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	Epidermal growth factor receptor	Homo sapiens			 1700						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66433	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	Epidermal growth factor receptor	Homo sapiens			 2000						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66434	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	Epidermal growth factor receptor	Homo sapiens			 290						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
66435	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	Epidermal growth factor receptor	Homo sapiens			 12						PubChem		10.7270/Q21Z42S7		aid1433		PubChem, PC	11/21/2008	4/23/2011	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
154840	Cc1cccc(Nc2ncnc3ccc(N)cc23)c1	InChI=1S/C15H14N4/c1-10-3-2-4-12(7-10)19-15-13-8-11(16)5-6-14(13)17-9-18-15/h2-9H,16H2,1H3,(H,17,18,19)	NFBCSWGEYDCCDW-UHFFFAOYSA-N	50133384	N4-(3-methylphenyl)-4,6-quinazolinediamine::Anilinoquinazoline, 4a::CHEMBL336113::N*4*-m-Tolyl-quinazoline-4,6-diamine	Epidermal growth factor receptor	Homo sapiens		 1000						37.00 C	Curated from the literature by BindingDB	10.1111/j.1747-0285.2008.00638.x	10.7270/Q29P303S	18324926	aid1799574		Larroque, AL; Peori, B; Williams, C; Fang, YQ; Qiu, Q; Rachid, Z; Jean-Claude, BJ	4/28/2008	10/31/2011	Mcgill University/Royal Victoria Hospital	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220590	104024215		CHEMBL336113					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
154841	Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C14H11BrN4/c15-9-2-1-3-11(6-9)19-14-12-7-10(16)4-5-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	IZQHULBHKPGOAP-UHFFFAOYSA-N	3294	CHEMBL52765::4-N-(3-bromophenyl)quinazoline-4,6-diamine::Anilinoquinazoline, 4b::4-Anilinoquinazoline deriv. 45	Epidermal growth factor receptor	Homo sapiens		 44						37.00 C	Curated from the literature by BindingDB	10.1111/j.1747-0285.2008.00638.x	10.7270/Q29P303S	18324926	aid1799574		Larroque, AL; Peori, B; Williams, C; Fang, YQ; Qiu, Q; Rachid, Z; Jean-Claude, BJ	4/28/2008	10/31/2011	Mcgill University/Royal Victoria Hospital	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5328042	8033036		CHEMBL52765					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
154842	Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1	InChI=1S/C14H11ClN4/c15-9-2-1-3-11(6-9)19-14-12-7-10(16)4-5-13(12)17-8-18-14/h1-8H,16H2,(H,17,18,19)	AWAYNEMCHILZCF-UHFFFAOYSA-N	50133382	CHEMBL343352::N4-(3-chlorophenyl)-4,6-quinazolinediamine::Anilinoquinazoline, 4c::N*4*-(3-Chloro-phenyl)-quinazoline-4,6-diamine::N4-(3-chlorophenyl)quinazoline-4,6-diamine	Epidermal growth factor receptor	Homo sapiens		 200						37.00 C	Curated from the literature by BindingDB	10.1111/j.1747-0285.2008.00638.x	10.7270/Q29P303S	18324926	aid1799574		Larroque, AL; Peori, B; Williams, C; Fang, YQ; Qiu, Q; Rachid, Z; Jean-Claude, BJ	4/28/2008	10/31/2011	Mcgill University/Royal Victoria Hospital	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133382&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11807783	104024213		CHEMBL343352					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
154843	CN(CCN(CCN(C)\N=N\c1ccc2ncnc(Nc3cccc(C)c3)c2c1)CCN1CCOCC1)\N=N\c1ccc2ncnc(Nc3cccc(C)c3)c2c1	InChI=1S/C42H50N14O/c1-31-7-5-9-33(25-31)47-41-37-27-35(11-13-39(37)43-29-45-41)49-51-53(3)15-17-55(19-20-56-21-23-57-24-22-56)18-16-54(4)52-50-36-12-14-40-38(28-36)42(46-30-44-40)48-34-10-6-8-32(2)26-34/h5-14,25-30H,15-24H2,1-4H3,(H,43,45,47)(H,44,46,48)	RDINVSMNTGHQSR-UHFFFAOYSA-N	81726	Bis-quinazolinotriazene, 5a	Epidermal growth factor receptor	Homo sapiens		 9.5e+2						37.00 C	Curated from the literature by BindingDB	10.1111/j.1747-0285.2008.00638.x	10.7270/Q29P303S	18324926	aid1799574		Larroque, AL; Peori, B; Williams, C; Fang, YQ; Qiu, Q; Rachid, Z; Jean-Claude, BJ	4/28/2008	10/31/2011	Mcgill University/Royal Victoria Hospital	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81726	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81726&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24851059	131342300							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
154844	CN(CCN(CCN(C)\N=N\c1ccc2ncnc(Nc3cccc(Br)c3)c2c1)CCN1CCOCC1)\N=N\c1ccc2ncnc(Nc3cccc(Br)c3)c2c1	InChI=1S/C40H44Br2N14O/c1-53(51-49-33-9-11-37-35(25-33)39(45-27-43-37)47-31-7-3-5-29(41)23-31)13-15-55(17-18-56-19-21-57-22-20-56)16-14-54(2)52-50-34-10-12-38-36(26-34)40(46-28-44-38)48-32-8-4-6-30(42)24-32/h3-12,23-28H,13-22H2,1-2H3,(H,43,45,47)(H,44,46,48)	YHFNFGDIARBZCQ-UHFFFAOYSA-N	81727	Bis-quinazolinotriazene, 5b	Epidermal growth factor receptor	Homo sapiens		 1.2e+2						37.00 C	Curated from the literature by BindingDB	10.1111/j.1747-0285.2008.00638.x	10.7270/Q29P303S	18324926	aid1799574		Larroque, AL; Peori, B; Williams, C; Fang, YQ; Qiu, Q; Rachid, Z; Jean-Claude, BJ	4/28/2008	10/31/2011	Mcgill University/Royal Victoria Hospital	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81727	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81727&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24816403	131342301							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
154845	CN(CCN(CCN(C)\N=N\c1ccc2ncnc(Nc3cccc(Cl)c3)c2c1)CCN1CCOCC1)\N=N\c1ccc2ncnc(Nc3cccc(Cl)c3)c2c1	InChI=1S/C40H44Cl2N14O/c1-53(51-49-33-9-11-37-35(25-33)39(45-27-43-37)47-31-7-3-5-29(41)23-31)13-15-55(17-18-56-19-21-57-22-20-56)16-14-54(2)52-50-34-10-12-38-36(26-34)40(46-28-44-38)48-32-8-4-6-30(42)24-32/h3-12,23-28H,13-22H2,1-2H3,(H,43,45,47)(H,44,46,48)	LHUARZLDBGCPLO-UHFFFAOYSA-N	81728	Bis-quinazolinotriazene, 5c	Epidermal growth factor receptor	Homo sapiens		 1.5e+2						37.00 C	Curated from the literature by BindingDB	10.1111/j.1747-0285.2008.00638.x	10.7270/Q29P303S	18324926	aid1799574		Larroque, AL; Peori, B; Williams, C; Fang, YQ; Qiu, Q; Rachid, Z; Jean-Claude, BJ	4/28/2008	10/31/2011	Mcgill University/Royal Victoria Hospital	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81728	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81728&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24851121	131342302							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169508	CCC1=C(CC(O)=O)c2cc(F)ccc2\C1=C/c1ccoc1 |c:2|	InChI=1S/C18H15FO3/c1-2-13-15(7-11-5-6-22-10-11)14-4-3-12(19)8-16(14)17(13)9-18(20)21/h3-8,10H,2,9H2,1H3,(H,20,21)	SYZJSPFCXVXDAA-UHFFFAOYSA-N	84518	Sulindac analogue, 15	Epidermal growth factor receptor	Homo sapiens		 9e+2							Curated from the literature by BindingDB	10.1002/cbic.200400192	10.7270/Q2KP80PS	15696596	aid1799615		Gourzoulidou, E; Carpintero, M; Baumhof, P; Giannis, A; Waldmann, H	3/28/2005	1/16/2012	Max-Planck-Institut FÜR Molekulare Physiologie	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84518&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10286274	136350618							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169513	CC1=C(CC(O)=O)c2cc(Cl)ccc2\C1=C/c1ccoc1 |c:1|	InChI=1S/C17H13ClO3/c1-10-14(6-11-4-5-21-9-11)13-3-2-12(18)7-16(13)15(10)8-17(19)20/h2-7,9H,8H2,1H3,(H,19,20)	TVDUJJFQSQWXMR-UHFFFAOYSA-N	84520	Sulindac analogue, 17	Epidermal growth factor receptor	Homo sapiens		 8e+3							Curated from the literature by BindingDB	10.1002/cbic.200400192	10.7270/Q2KP80PS	15696596	aid1799615		Gourzoulidou, E; Carpintero, M; Baumhof, P; Giannis, A; Waldmann, H	3/28/2005	1/16/2012	Max-Planck-Institut FÜR Molekulare Physiologie	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84520&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10171769	136350620							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169519	CC1=C(CC(O)=O)c2ccc(Br)cc2\C1=C/c1ccsc1 |c:1|	InChI=1S/C17H13BrO2S/c1-10-14(6-11-4-5-21-9-11)16-7-12(18)2-3-13(16)15(10)8-17(19)20/h2-7,9H,8H2,1H3,(H,19,20)	ALAVELGECUJLKK-UHFFFAOYSA-N	84522	Sulindac analogue, 19	Epidermal growth factor receptor	Homo sapiens		 1.2e+4							Curated from the literature by BindingDB	10.1002/cbic.200400192	10.7270/Q2KP80PS	15696596	aid1799615		Gourzoulidou, E; Carpintero, M; Baumhof, P; Giannis, A; Waldmann, H	3/28/2005	1/16/2012	Max-Planck-Institut FÜR Molekulare Physiologie	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84522&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10406261	136350622							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169527	CC1=C(CC(O)=O)c2ccc(Br)cc2\C1=C/c1ccoc1 |c:1|	InChI=1S/C17H13BrO3/c1-10-14(6-11-4-5-21-9-11)16-7-12(18)2-3-13(16)15(10)8-17(19)20/h2-7,9H,8H2,1H3,(H,19,20)	ZBOCJDCPGUKFJE-UHFFFAOYSA-N	84524	Sulindac analogue, 21	Epidermal growth factor receptor	Homo sapiens		 2.2e+4							Curated from the literature by BindingDB	10.1002/cbic.200400192	10.7270/Q2KP80PS	15696596	aid1799615		Gourzoulidou, E; Carpintero, M; Baumhof, P; Giannis, A; Waldmann, H	3/28/2005	1/16/2012	Max-Planck-Institut FÜR Molekulare Physiologie	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84524&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57339733	136350624							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169589	Brc1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1 |w:8.20|	InChI=1S/C16H9BrN2O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)14-15(20)9-3-1-2-4-11(9)18-14/h1-7,18H,(H,19,21)	IEQQJQHHJMQETK-UHFFFAOYSA-N	54680	cid_5287845::UNM-0000305770::(3Z)-5-bromanyl-3-(3-oxidanylidene-1H-indol-2-ylidene)-1H-indol-2-one::(3Z)-5-bromo-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one::(3Z)-5-bromo-3-(3-ketoindolin-2-ylidene)oxindole	Epidermal growth factor receptor	Homo sapiens		>1.0e+4					7.0000	22.00 C	Curated from the literature by BindingDB	10.1002/cbic.200400108	10.7270/Q2B56H8H	15742375	aid1799617		Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G	3/28/2005	1/16/2012	Schering	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54680	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54680&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5287845	252634706							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169590	OS(=O)(=O)c1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1 |w:12.21|	InChI=1S/C16H10N2O5S/c19-15-9-3-1-2-4-11(9)17-14(15)13-10-7-8(24(21,22)23)5-6-12(10)18-16(13)20/h1-7,17H,(H,18,20)(H,21,22,23)	IHBOEHLUIBMBMY-UHFFFAOYSA-N	84534	Indirubin derivative, 20	Epidermal growth factor receptor	Homo sapiens		>1.0e+4					7.0000	22.00 C	Curated from the literature by BindingDB	10.1002/cbic.200400108	10.7270/Q2B56H8H	15742375	aid1799617		Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G	3/28/2005	1/16/2012	Schering	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84534&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5288641	136350634							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169591	CN(C)CCN(C)S(=O)(=O)c1ccc2NC(=O)C(C3=Nc4ccccc4C3(C)O)c2c1 |t:18|	InChI=1S/C22H26N4O4S/c1-22(28)16-7-5-6-8-18(16)23-20(22)19-15-13-14(9-10-17(15)24-21(19)27)31(29,30)26(4)12-11-25(2)3/h5-10,13,19,28H,11-12H2,1-4H3,(H,24,27)	BBKQDKWGGKCIQA-UHFFFAOYSA-N	84553	Indirubin derivative, 28b::Indirubin derivative, 28a	Epidermal growth factor receptor	Homo sapiens		>1.0e+4					7.0000	22.00 C	Curated from the literature by BindingDB	10.1002/cbic.200400108	10.7270/Q2B56H8H	15742375	aid1799617		Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G	3/28/2005	1/16/2012	Schering	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84553&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91898890	136350653							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169592	CN(C)CCN(C)S(=O)(=O)c1ccc2NC(=O)C(C3=Nc4ccccc4C3(C)O)c2c1 |t:18|	InChI=1S/C22H26N4O4S/c1-22(28)16-7-5-6-8-18(16)23-20(22)19-15-13-14(9-10-17(15)24-21(19)27)31(29,30)26(4)12-11-25(2)3/h5-10,13,19,28H,11-12H2,1-4H3,(H,24,27)	BBKQDKWGGKCIQA-UHFFFAOYSA-N	84553	Indirubin derivative, 28b::Indirubin derivative, 28a	Epidermal growth factor receptor	Homo sapiens		>1.0e+4					7.0000	22.00 C	Curated from the literature by BindingDB	10.1002/cbic.200400108	10.7270/Q2B56H8H	15742375	aid1799617		Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G	3/28/2005	1/16/2012	Schering	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84553&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91898890	136350653							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169593	CN(C)CCN(C)S(=O)(=O)c1ccc2NC(=O)C(C3=Nc4ccccc4C3(O)CC=C)c2c1 |t:18|	InChI=1S/C24H28N4O4S/c1-5-12-24(30)18-8-6-7-9-20(18)25-22(24)21-17-15-16(10-11-19(17)26-23(21)29)33(31,32)28(4)14-13-27(2)3/h5-11,15,21,30H,1,12-14H2,2-4H3,(H,26,29)	SJDBWFBIDFWMRX-UHFFFAOYSA-N	84555	Indirubin derivative, 30b::Indirubin derivative, 30a	Epidermal growth factor receptor	Homo sapiens		>1.0e+4					7.0000	22.00 C	Curated from the literature by BindingDB	10.1002/cbic.200400108	10.7270/Q2B56H8H	15742375	aid1799617		Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G	3/28/2005	1/16/2012	Schering	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84555	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84555&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91898891	136350655							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
169594	CN(C)CCN(C)S(=O)(=O)c1ccc2NC(=O)C(C3=Nc4ccccc4C3(O)CC=C)c2c1 |t:18|	InChI=1S/C24H28N4O4S/c1-5-12-24(30)18-8-6-7-9-20(18)25-22(24)21-17-15-16(10-11-19(17)26-23(21)29)33(31,32)28(4)14-13-27(2)3/h5-11,15,21,30H,1,12-14H2,2-4H3,(H,26,29)	SJDBWFBIDFWMRX-UHFFFAOYSA-N	84555	Indirubin derivative, 30b::Indirubin derivative, 30a	Epidermal growth factor receptor	Homo sapiens		>1.0e+4					7.0000	22.00 C	Curated from the literature by BindingDB	10.1002/cbic.200400108	10.7270/Q2B56H8H	15742375	aid1799617		Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G	3/28/2005	1/16/2012	Schering	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84555	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84555&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91898891	136350655							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
170117	OC(=O)CC(=O)OCCOCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H22BrFN4O7/c1-2-21(31)29-19-10-15-18(27-13-28-24(15)30-17-4-3-14(25)9-16(17)26)11-20(19)36-7-5-35-6-8-37-23(34)12-22(32)33/h2-4,9-11,13H,1,5-8,12H2,(H,29,31)(H,32,33)(H,27,28,30)	XRHZCKCSIVHXIK-UHFFFAOYSA-N	18748	US8846699, 70	Epidermal growth factor receptor	Homo sapiens		 956					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18748	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18748&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91618185	249493543					C01656		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
170295	CC(C)Nc1nc(nc2ccc(cc12)C#CCO)-c1ccco1	InChI=1S/C18H17N3O2/c1-12(2)19-17-14-11-13(5-3-9-22)7-8-15(14)20-18(21-17)16-6-4-10-23-16/h4,6-8,10-12,22H,9H2,1-2H3,(H,19,20,21)	RXMATXXHYMCLLO-UHFFFAOYSA-N	84649	TC-28	Epidermal growth factor receptor	Homo sapiens		>1.00e+5					7.5000	4.00 C	Curated from the literature by BindingDB	10.1002/cbic.200800600	10.7270/Q24F1P8K	19199284	aid1799625		Sardon, T; Cottin, T; Xu, J; Giannis, A; Vernos, I	2/13/2009	2/6/2012	Parc De Recerca Biomedica De Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84649	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84649&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			46843405	136350749							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
170296	CC(C)Nc1nc(nc2ccc(C=CC(C)(C)O)cc12)-c1ccco1	InChI=1S/C20H23N3O2/c1-13(2)21-18-15-12-14(9-10-20(3,4)24)7-8-16(15)22-19(23-18)17-6-5-11-25-17/h5-13,24H,1-4H3,(H,21,22,23)	INWQHHRLNZWEFG-UHFFFAOYSA-N	84650	TC-34	Epidermal growth factor receptor	Homo sapiens		>1.00e+5					7.5000	4.00 C	Curated from the literature by BindingDB	10.1002/cbic.200800600	10.7270/Q24F1P8K	19199284	aid1799625		Sardon, T; Cottin, T; Xu, J; Giannis, A; Vernos, I	2/13/2009	2/6/2012	Parc De Recerca Biomedica De Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84650	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84650&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57339806	136350750							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
170297	OCC=Cc1ccc2ncnc(Nc3cccc(F)c3)c2c1	InChI=1S/C17H14FN3O/c18-13-4-1-5-14(10-13)21-17-15-9-12(3-2-8-22)6-7-16(15)19-11-20-17/h1-7,9-11,22H,8H2,(H,19,20,21)	IDHRRIVXMOYZOP-UHFFFAOYSA-N	84651	TC-107	Epidermal growth factor receptor	Homo sapiens		>1.00e+5					7.5000	4.00 C	Curated from the literature by BindingDB	10.1002/cbic.200800600	10.7270/Q24F1P8K	19199284	aid1799625		Sardon, T; Cottin, T; Xu, J; Giannis, A; Vernos, I	2/13/2009	2/6/2012	Parc De Recerca Biomedica De Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84651&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57339807	136350751							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
176157	CCOC(=O)CC(=O)OCCOCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C26H26BrFN4O7/c1-3-23(33)31-21-12-17-20(29-15-30-26(17)32-19-6-5-16(27)11-18(19)28)13-22(21)38-9-7-36-8-10-39-25(35)14-24(34)37-4-2/h3,5-6,11-13,15H,1,4,7-10,14H2,2H3,(H,31,33)(H,29,30,32)	PPNPTLLSQTYHSE-UHFFFAOYSA-N	18747	US8846699, 69	Epidermal growth factor receptor	Homo sapiens		 246					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18747&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91618184	249493542							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
176887	CC(COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C24H26BrFN6O3/c1-5-22(33)30-20-9-16-19(10-21(20)35-12-14(2)29-23(34)11-32(3)4)27-13-28-24(16)31-18-7-6-15(25)8-17(18)26/h5-10,13-14H,1,11-12H2,2-4H3,(H,29,34)(H,30,33)(H,27,28,31)	VHQAZGVURZXKGM-UHFFFAOYSA-N	18749	US8846699, 153	Epidermal growth factor receptor	Homo sapiens		 172					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18749	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18749&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91618186	249493544							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
176889	CC(C)C(COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C26H30BrFN6O3/c1-6-24(35)31-21-10-17-20(29-14-30-26(17)33-19-8-7-16(27)9-18(19)28)11-23(21)37-13-22(15(2)3)32-25(36)12-34(4)5/h6-11,14-15,22H,1,12-13H2,2-5H3,(H,31,35)(H,32,36)(H,29,30,33)	ZEIPSBCNYPQWSX-UHFFFAOYSA-N	18750	US8846699, 156	Epidermal growth factor receptor	Homo sapiens		 149					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18750&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69106185	249493545							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200455	CC(C)([O-])CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)c12	InChI=1S/C26H24ClF3N5O3/c1-25(2,37)14-22(36)31-9-11-35-10-8-20-23(35)24(33-15-32-20)34-17-6-7-21(19(27)13-17)38-18-5-3-4-16(12-18)26(28,29)30/h3-8,10,12-13,15H,9,11,14H2,1-2H3,(H,31,36)(H,32,33,34)/q-1	QGZVSVHWQCGWDX-UHFFFAOYSA-N	92453	TAK-285	Epidermal growth factor receptor	Homo sapiens		 23					7.5000		Curated from the literature by BindingDB	10.1074/jbc.M110.206193	10.7270/Q27W69TH	21454582	aid1799771		Aertgeerts, K; Skene, R; Yano, J; Sang, BC; Zou, H; Snell, G; Jennings, A; Iwamoto, K; Habuka, N; Hirokawa, A; Ishikawa, T; Tanaka, T; Miki, H; Ohta, Y; Sogabe, S	5/27/2011	9/10/2012	Takeda Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92453&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70701994	160844950							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200456	[O-]CCOCn1ccc2ncnc(Nc3cnc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)c12	InChI=1S/C21H16ClF3N5O3/c22-16-9-14(10-26-20(16)33-15-3-1-2-13(8-15)21(23,24)25)29-19-18-17(27-11-28-19)4-5-30(18)12-32-7-6-31/h1-5,8-11H,6-7,12H2,(H,27,28,29)/q-1	SBMNMLFWVOAHCS-UHFFFAOYSA-N	92454	SYR127063	Epidermal growth factor receptor	Homo sapiens		 429					7.5000		Curated from the literature by BindingDB	10.1074/jbc.M110.206193	10.7270/Q27W69TH	21454582	aid1799771		Aertgeerts, K; Skene, R; Yano, J; Sang, BC; Zou, H; Snell, G; Jennings, A; Iwamoto, K; Habuka, N; Hirokawa, A; Ishikawa, T; Tanaka, T; Miki, H; Ohta, Y; Sogabe, S	5/27/2011	9/10/2012	Takeda Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92454&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70701995	160844951							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200457	COCCOc1cc2c(cc1OCCOC)ncnc2Nc3cccc(c3)C#C	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	Erlotinib::OSI-774::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::CHEMBL553::ERLOTINIB HYDROCHLORIDE::cid_176870::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::Tarceva::US9409845, Table 1, Compound 22: erlotinib::US10189853, erlotinib::US9730934, Erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::WO2022090481, Example erlotinib	Epidermal growth factor receptor	Homo sapiens		 0.7					7.5000		Curated from the literature by BindingDB	10.1074/jbc.M110.206193	10.7270/Q27W69TH	21454582	aid1799771		Aertgeerts, K; Skene, R; Yano, J; Sang, BC; Zou, H; Snell, G; Jennings, A; Iwamoto, K; Habuka, N; Hirokawa, A; Ishikawa, T; Tanaka, T; Miki, H; Ohta, Y; Sogabe, S	5/27/2011	9/10/2012	Takeda Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065		CHEMBL553	DB00530				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200458	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::cid_208908::CHEMBL554::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::LAPATINIB DITOSYLATE::GW572016::Tykerb::US9730934, Lapatinib ditosylate::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib	Epidermal growth factor receptor	Homo sapiens		 3					7.5000		Curated from the literature by BindingDB	10.1074/jbc.M110.206193	10.7270/Q27W69TH	21454582	aid1799771		Aertgeerts, K; Skene, R; Yano, J; Sang, BC; Zou, H; Snell, G; Jennings, A; Iwamoto, K; Habuka, N; Hirokawa, A; Ishikawa, T; Tanaka, T; Miki, H; Ohta, Y; Sogabe, S	5/27/2011	9/10/2012	Takeda Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			208908	8035064		CHEMBL554	DB01259				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200979	Cn1c(O)csc1=NN=C1SC(=C)C(=O)N1CC=C |w:7.8,9.10|	InChI=1S/C11H12N4O2S2/c1-4-5-15-9(17)7(2)19-11(15)13-12-10-14(3)8(16)6-18-10/h4,6,16H,1-2,5H2,3H3	IJDRIAQFBMTDHF-UHFFFAOYSA-N	92632	Thiazolidine-dione, 1	Epidermal growth factor receptor	Homo sapiens		 6e+3							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92632	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92632&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899445	160845125							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200984	CC(=C)CN1C(SC(=C)C1=O)=NN=c1scc(O)n1C |w:12.12,5.5|	InChI=1S/C12H14N4O2S2/c1-7(2)5-16-10(18)8(3)20-12(16)14-13-11-15(4)9(17)6-19-11/h6,17H,1,3,5H2,2,4H3	MGXJFHQMSHIMIV-UHFFFAOYSA-N	92633	Thiazolidine-dione, 2	Epidermal growth factor receptor	Homo sapiens		 1e+3							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92633	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92633&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899446	160845126							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200989	CN(C)Cc1sc(=NN=c2scc(O)n2C)n(CC(C)=C)c1O |w:8.7|	InChI=1S/C14H21N5O2S2/c1-9(2)6-19-12(21)10(7-17(3)4)23-14(19)16-15-13-18(5)11(20)8-22-13/h8,20-21H,1,6-7H2,2-5H3	RHAPCRNMYBVFGA-UHFFFAOYSA-N	92634	Thiazolidine-dione, 3	Epidermal growth factor receptor	Homo sapiens		 2e+3							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92634	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92634&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899447	160845127							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200994	CC(=C)Cn1c(O)csc1=NN=c1scc(O)n1C |w:11.11|	InChI=1S/C11H14N4O2S2/c1-7(2)4-15-9(17)6-19-11(15)13-12-10-14(3)8(16)5-18-10/h5-6,16-17H,1,4H2,2-3H3	GIBVKNSMYATPDW-UHFFFAOYSA-N	92635	Thiazolidine-dione, 4	Epidermal growth factor receptor	Homo sapiens		>5.0e+4							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92635	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92635&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899448	160845128							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
200998	Cc1sc(=NN=c2scc(O)n2C)n(CC=C)c1O |w:5.4|	InChI=1S/C11H14N4O2S2/c1-4-5-15-9(17)7(2)19-11(15)13-12-10-14(3)8(16)6-18-10/h4,6,16-17H,1,5H2,2-3H3	GOJRMCNDIMTXOB-UHFFFAOYSA-N	92636	Thiazolidine-dione, 5	Epidermal growth factor receptor	Homo sapiens		>5.0e+4							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92636&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899449	160845129							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
201002	CC(=C)Cn1c(O)c(C)sc1=NN=c1scc(O)n1C |w:12.12|	InChI=1S/C12H16N4O2S2/c1-7(2)5-16-10(18)8(3)20-12(16)14-13-11-15(4)9(17)6-19-11/h6,17-18H,1,5H2,2-4H3	TZWYPINHXVSJSP-UHFFFAOYSA-N	92637	Thiazolidine-dione, 6	Epidermal growth factor receptor	Homo sapiens		>5.0e+4							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92637&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899450	160845130							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
201006	CC(=C)Cn1c(O)c(O)sc1=NN=c1scc(O)n1C |w:12.12|	InChI=1S/C11H14N4O3S2/c1-6(2)4-15-8(17)9(18)20-11(15)13-12-10-14(3)7(16)5-19-10/h5,16-18H,1,4H2,2-3H3	QCYDMMYMXPOEPI-UHFFFAOYSA-N	92638	Thiazolidine-dione, 7	Epidermal growth factor receptor	Homo sapiens		>1.00e+5							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92638	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92638&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899451	160845131							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
201010	CC(=C)Cn1c(O)c(CO)sc1=NN=c1scc(O)n1C |w:13.13|	InChI=1S/C12H16N4O3S2/c1-7(2)4-16-10(19)8(5-17)21-12(16)14-13-11-15(3)9(18)6-20-11/h6,17-19H,1,4-5H2,2-3H3	OHGXQWZYWJYQPA-UHFFFAOYSA-N	92639	Thiazolidine-dione, 8	Epidermal growth factor receptor	Homo sapiens		>5.0e+4							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92639	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92639&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899452	160845132							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
201013	Cn1c(O)csc1=NN=c1sc(CC(O)=O)c(O)n1CC=C |w:7.8|	InChI=1S/C12H14N4O4S2/c1-3-4-16-10(20)7(5-9(18)19)22-12(16)14-13-11-15(2)8(17)6-21-11/h3,6,17,20H,1,4-5H2,2H3,(H,18,19)	LSSPQUWDKRNSKJ-UHFFFAOYSA-N	92640	Thiazolidine-dione, 9	Epidermal growth factor receptor	Homo sapiens		>1.00e+5							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92640	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92640&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899453	160845133							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
201017	CC(=C)Cn1c(O)c(OS(O)=O)sc1=NN=c1scc(O)n1C |w:15.15|	InChI=1S/C11H14N4O5S3/c1-6(2)4-15-8(17)9(20-23(18)19)22-11(15)13-12-10-14(3)7(16)5-21-10/h5,16-17H,1,4H2,2-3H3,(H,18,19)	WXOZKXJCPMZCFA-UHFFFAOYSA-N	92641	Thiazolidine-dione, 10	Epidermal growth factor receptor	Homo sapiens		 1.00e+5							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92641&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91899454	160845134					C01615		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
201022	c1cc(ccc1C2=COc3cc(cc(c3C2=O)O)O)O	InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H	TZBJGXHYKVUXJN-UHFFFAOYSA-N	19459	Prunetol::Genisteol::CHEMBL44::US8552057, 2::cid_5280961::Genistein, 8::5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one::Genistein	Epidermal growth factor receptor	Homo sapiens		 1e+3							Curated from the literature by BindingDB		10.7270/Q2319TGH	2176210	aid1799815		Geissler, JF; Traxler, P; Regenass, U; Murray, BJ; Roesel, JL; Meyer, T; McGlynn, E; Storni, A; Lydon, NB	12/25/1990	1/7/2013	Ciba-Geigy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19459&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	GEN	1X7J,1X7R,5AV4,5AUZ,8FOA,3KGU,3KGT,2QA8,1QKM,6G8G,4FJ1,5KDA,7NFB	5280961	46519480		CHEMBL44	DB01645		C06563		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218469	Fc1ccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)\C=C\CN2CCCOCC2)cc1Cl	InChI=1S/C24H25ClFN5O2S/c25-18-13-16(4-5-19(18)26)29-23-22-17-6-9-31(14-20(17)34-24(22)28-15-27-23)21(32)3-1-7-30-8-2-11-33-12-10-30/h1,3-5,13,15H,2,6-12,14H2,(H,27,28,29)	RWLIEDPJUCGAIH-UHFFFAOYSA-N	101226	US8524722, 5	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101226	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101226&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25195479	165223687							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218470	Fc1ccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)\C=C\CN2C3CCC2CC3)cc1Cl	InChI=1S/C25H25ClFN5OS/c26-19-12-15(3-8-20(19)27)30-24-23-18-9-11-31(13-21(18)34-25(23)29-14-28-24)22(33)2-1-10-32-16-4-5-17(32)7-6-16/h1-3,8,12,14,16-17H,4-7,9-11,13H2,(H,28,29,30)	ZXPWQTWHRXRMRM-UHFFFAOYSA-N	101227	US8524722, 10	Epidermal growth factor receptor	Homo sapiens		 1.1					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101227	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101227&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25221216	165223688							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218471	CC(C)(CN1CCOCC1)NC\C=C\C(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)c(Cl)c3)c21	InChI=1S/C27H32ClFN6O2S/c1-27(2,16-34-10-12-37-13-11-34)32-8-3-4-23(36)35-9-7-19-22(15-35)38-26-24(19)25(30-17-31-26)33-18-5-6-21(29)20(28)14-18/h3-6,14,17,32H,7-13,15-16H2,1-2H3,(H,30,31,33)	YAZVLKFUKNILLX-UHFFFAOYSA-N	101228	US8524722, 12	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101228	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101228&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25221214	165223689							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218472	Fc1ccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)\C=C\[C@@H]2CCCN2)cc1Cl |r|	InChI=1S/C22H21ClFN5OS/c23-16-10-14(3-5-17(16)24)28-21-20-15-7-9-29(11-18(15)31-22(20)27-12-26-21)19(30)6-4-13-2-1-8-25-13/h3-6,10,12-13,25H,1-2,7-9,11H2,(H,26,27,28)	SMQXTKSNVNONRG-UHFFFAOYSA-N	101229	US8524722, 13	Epidermal growth factor receptor	Homo sapiens		 2.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101229	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101229&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25222665	165223690							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218473	CN1CCC[C@H]1\C=C\C(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)c(Cl)c3)c21 |r|	InChI=1S/C23H23ClFN5OS/c1-29-9-2-3-15(29)5-7-20(31)30-10-8-16-19(12-30)32-23-21(16)22(26-13-27-23)28-14-4-6-18(25)17(24)11-14/h4-7,11,13,15H,2-3,8-10,12H2,1H3,(H,26,27,28)	IHAMQXNCAXXWHB-UHFFFAOYSA-N	101230	US8524722, 14	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101230	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101230&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25221099	165223691							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218474	C[C@@H](Nc1ncnc2sc3CN(CCc3c12)C(=O)\C=C\CN(C)C)c1ccccc1 |r|	InChI=1S/C23H27N5OS/c1-16(17-8-5-4-6-9-17)26-22-21-18-11-13-28(20(29)10-7-12-27(2)3)14-19(18)30-23(21)25-15-24-22/h4-10,15-16H,11-14H2,1-3H3,(H,24,25,26)	BVGZQNBERZRYJK-UHFFFAOYSA-N	50330241	CHEMBL1271561::US8524722, 23::(E)-4-(Dimethylamino)-1-(4-[(1R)-1-phenylethyl]amino-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl)-2-buten-1-one	Epidermal growth factor receptor	Homo sapiens		 4.6					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330241	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330241&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49788490	123109356		CHEMBL1271561					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218475	COCCN(CCOC)C\C=C\C(=O)N1CCc2c(C1)sc1ncnc(Nc3ccc(F)c(Cl)c3)c21	InChI=1S/C25H29ClFN5O3S/c1-34-12-10-31(11-13-35-2)8-3-4-22(33)32-9-7-18-21(15-32)36-25-23(18)24(28-16-29-25)30-17-5-6-20(27)19(26)14-17/h3-6,14,16H,7-13,15H2,1-2H3,(H,28,29,30)	FVHRXNQLQCFNOX-UHFFFAOYSA-N	101231	US8524722, 31	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101231	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101231&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116996	165223692							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218476	CN(C)C(=O)N1CCN(C\C=C\C(=O)N2CCc3c(C2)sc2ncnc(Nc4ccc(F)c(Cl)c4)c32)CC1	InChI=1S/C26H29ClFN7O2S/c1-32(2)26(37)34-12-10-33(11-13-34)8-3-4-22(36)35-9-7-18-21(15-35)38-25-23(18)24(29-16-30-25)31-17-5-6-20(28)19(27)14-17/h3-6,14,16H,7-13,15H2,1-2H3,(H,29,30,31)	PJXFDSFGZUPIKW-UHFFFAOYSA-N	101232	US8524722, 70	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101232	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101232&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116823	165223693							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218477	CN(C)C\C=C\C(=O)N1Cc2sc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2C1	InChI=1S/C20H19ClFN5OS/c1-26(2)7-3-4-17(28)27-9-13-16(10-27)29-20-18(13)19(23-11-24-20)25-12-5-6-15(22)14(21)8-12/h3-6,8,11H,7,9-10H2,1-2H3,(H,23,24,25)	LCOUDBVKMKTAKW-UHFFFAOYSA-N	101233	US8524722, 81	Epidermal growth factor receptor	Homo sapiens		 12					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101233	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101233&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			46938197	165223694							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218478	CC(C)N(C)C\C=C\C(=O)N1Cc2sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3c2C1	InChI=1S/C22H23Cl2N5OS/c1-13(2)28(3)8-4-5-19(30)29-10-15-18(11-29)31-22-20(15)21(25-12-26-22)27-14-6-7-16(23)17(24)9-14/h4-7,9,12-13H,8,10-11H2,1-3H3,(H,25,26,27)	HPLAILWNQKGFFP-UHFFFAOYSA-N	101234	US8524722, 84	Epidermal growth factor receptor	Homo sapiens		 1.4					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101234	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101234&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116878	165223695							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218479	CN(C)C\C=C\C(=O)N1Cc2sc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2C1	InChI=1S/C27H25ClFN5O2S/c1-33(2)10-4-7-24(35)34-13-20-23(14-34)37-27-25(20)26(30-16-31-27)32-19-8-9-22(21(28)12-19)36-15-17-5-3-6-18(29)11-17/h3-9,11-12,16H,10,13-15H2,1-2H3,(H,30,31,32)	HVEVWNBOUFTSIY-UHFFFAOYSA-N	101235	US8524722, 86	Epidermal growth factor receptor	Homo sapiens		 5.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101235	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101235&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116918	165223696							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218480	CN(C)C\C=C\C(=O)N1Cc2sc3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c3c2C1	InChI=1S/C26H25ClN6O2S/c1-32(2)11-5-7-23(34)33-13-19-22(14-33)36-26-24(19)25(29-16-30-26)31-17-8-9-21(20(27)12-17)35-15-18-6-3-4-10-28-18/h3-10,12,16H,11,13-15H2,1-2H3,(H,29,30,31)	FKHGTMQRLLWPJO-UHFFFAOYSA-N	101236	US8524722, 87	Epidermal growth factor receptor	Homo sapiens		 19					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101236	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101236&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116992	165223697							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218481	CC(C)N(C)C\C=C\C(=O)N1CCc2c(C1)oc1ncnc(Nc3ccc(F)c(Cl)c3)c21	InChI=1S/C23H25ClFN5O2/c1-14(2)29(3)9-4-5-20(31)30-10-8-16-19(12-30)32-23-21(16)22(26-13-27-23)28-15-6-7-18(25)17(24)11-15/h4-7,11,13-14H,8-10,12H2,1-3H3,(H,26,27,28)	KKAZCEHVMNTCEU-UHFFFAOYSA-N	101237	US8524722, 90	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101237	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101237&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116812	165223698							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218482	CN(C)C\C=C\C(=O)N1CCc2c(C1)sc1ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c21	InChI=1S/C23H21ClFN5OS/c1-29(2)8-3-4-20(31)30-9-7-16-19(13-30)32-23-21(16)22(14(11-26)12-27-23)28-15-5-6-18(25)17(24)10-15/h3-6,10,12H,7-9,13H2,1-2H3,(H,27,28)	NVLFBEYJQFJUAT-UHFFFAOYSA-N	101238	US8524722, 95	Epidermal growth factor receptor	Homo sapiens		 10					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101238	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101238&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116995	165223699							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218483	Clc1ccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)\C=C\CNC23CC4CC(CC(C4)C2)C3)cc1Cl |TLB:34:25:32:28.29.30,THB:33:25:28:32.31.30,33:31:28:25.34.26,24:25:32:28.29.30,34:29:32:25.33.26|	InChI=1S/C29H31Cl2N5OS/c30-22-4-3-20(11-23(22)31)35-27-26-21-5-7-36(15-24(21)38-28(26)33-16-32-27)25(37)2-1-6-34-29-12-17-8-18(13-29)10-19(9-17)14-29/h1-4,11,16-19,34H,5-10,12-15H2,(H,32,33,35)	GXLYEAVLPHCXKU-UHFFFAOYSA-N	101239	US8524722, 119	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101239	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101239&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116997	165223700							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218484	CC(C)C(C)C\C=C\C(=O)N1CCc2c(C1)sc1ncnc(Nc3cc(O)cc(Cl)c3)c21	InChI=1S/C24H27ClN4O2S/c1-14(2)15(3)5-4-6-21(31)29-8-7-19-20(12-29)32-24-22(19)23(26-13-27-24)28-17-9-16(25)10-18(30)11-17/h4,6,9-11,13-15,30H,5,7-8,12H2,1-3H3,(H,26,27,28)	FHNHKAFWHQJIDM-UHFFFAOYSA-N	101240	US8524722, 123	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101240	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101240&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116858	165223701							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218485	CN(C\C=C\C(=O)N1CCc2c(C1)sc1ncnc(Nc3cc(O)c(Cl)c(Cl)c3)c21)C(C)(C)C	InChI=1S/C24H27Cl2N5O2S/c1-24(2,3)30(4)8-5-6-19(33)31-9-7-15-18(12-31)34-23-20(15)22(27-13-28-23)29-14-10-16(25)21(26)17(32)11-14/h5-6,10-11,13,32H,7-9,12H2,1-4H3,(H,27,28,29)	IMDIVOQCLUSJJU-UHFFFAOYSA-N	101241	US8524722, 134	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101241	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101241&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116936	165223702							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218486	CC(C)N(C)C\C=C\C(=O)N1CCc2sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3c2C1	InChI=1S/C23H25Cl2N5OS/c1-14(2)29(3)9-4-5-20(31)30-10-8-19-16(12-30)21-22(26-13-27-23(21)32-19)28-15-6-7-17(24)18(25)11-15/h4-7,11,13-14H,8-10,12H2,1-3H3,(H,26,27,28)	LUAGTXJZTHBNFU-UHFFFAOYSA-N	101242	US8524722, 139	Epidermal growth factor receptor	Homo sapiens		 9.2					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101242	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101242&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116894	165223703							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218487	Clc1ccc(Nc2ncnc3sc4CN(CCCc4c23)C(=O)\C=C\CN2CCCOCC2)cc1Cl	InChI=1S/C25H27Cl2N5O2S/c26-19-7-6-17(14-20(19)27)30-24-23-18-4-1-10-32(15-21(18)35-25(23)29-16-28-24)22(33)5-2-8-31-9-3-12-34-13-11-31/h2,5-7,14,16H,1,3-4,8-13,15H2,(H,28,29,30)	IXUDUNWMTNELOE-UHFFFAOYSA-N	101243	US8524722, 143	Epidermal growth factor receptor	Homo sapiens		 1.0					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101243	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101243&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25222663	165223704							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218488	Clc1ccc(Nc2c(cnc3sc4CN(CCc4c23)C(=O)\C=C\CN2CCCOCC2)C#N)cc1Cl	InChI=1S/C26H25Cl2N5O2S/c27-20-5-4-18(13-21(20)28)31-25-17(14-29)15-30-26-24(25)19-6-9-33(16-22(19)36-26)23(34)3-1-7-32-8-2-11-35-12-10-32/h1,3-5,13,15H,2,6-12,16H2,(H,30,31)	JMUZSSQPGDQMCG-UHFFFAOYSA-N	101244	US8524722, 148	Epidermal growth factor receptor	Homo sapiens		 4.3					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101244	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101244&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116979	165223705							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
218489	CC(C)N(C)C\C=C\C(=O)N1CCc2c(C1)sc1ncc(C#N)c(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c21	InChI=1S/C33H32FN7OS/c1-21(2)39(3)12-5-8-30(42)40-13-11-27-29(20-40)43-33-31(27)32(24(16-35)17-36-33)38-26-9-10-28-23(15-26)18-37-41(28)19-22-6-4-7-25(34)14-22/h4-10,14-15,17-18,21H,11-13,19-20H2,1-3H3,(H,36,38)	LGPPNTOFGJQREB-UHFFFAOYSA-N	101245	US8524722, 151	Epidermal growth factor receptor	Homo sapiens		 6.4					7.0000	22.00 C	US Patent		10.7270/Q2B856RQ		aid1800017	US8524722	Schirok, H; Li-Sommer, Y; Brands, M; Lobell, M; Tersteegen, A; Himmel, H; Schlemmer, K; Lang, D; Petersen, K; Renz, M; Mumberg, D; Hoffmann, J; Siemeister, G; Bomer, U	9/3/2013	10/18/2013	Bayer Intellectual Property	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101245	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101245&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58116927	165223706							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
233605	FCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCC1	InChI=1S/C25H26ClF2N5O2/c26-19-13-17(6-7-20(19)28)31-25-18-14-22(23(35-12-8-27)15-21(18)29-16-30-25)32-24(34)5-4-11-33-9-2-1-3-10-33/h4-7,13-16H,1-3,8-12H2,(H,32,34)(H,29,30,31)	GFMMDHSSOIPFTF-UHFFFAOYSA-N	112498	US8623883, No. 1	Epidermal growth factor receptor	Homo sapiens		 6.44					7.4000	25.00 C	US Patent		10.7270/Q29885P7		aid1800296	US8623883	Fakhoury, SA; Lee, HT; Reed, JE; Schlosser, KM; Sexton, KE; Tecle, H; Winters, RT	1/7/2014	7/22/2014	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112498&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11584208	194690239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
233606	COc1cc2c(cc1NC(=O)/C=C/CN3CCCCC3)c(ncn2)Nc4ccc(c(c4)Cl)F	InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8,12-15H,2-4,9-11H2,1H3,(H,30,32)(H,27,28,29)	LVXJQMNHJWSHET-UHFFFAOYSA-N	112499	DACOMITINIB::US8623883, No. 2::WO2022090481, Example dacomitinib	Epidermal growth factor receptor	Homo sapiens		 6.9					7.4000	25.00 C	US Patent		10.7270/Q29885P7		aid1800296	US8623883	Fakhoury, SA; Lee, HT; Reed, JE; Schlosser, KM; Sexton, KE; Tecle, H; Winters, RT	1/7/2014	7/22/2014	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112499&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1C9	4I24,4I23	11511120	194690240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
233607	FC(F)COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCC1	InChI=1S/C25H25ClF3N5O2/c26-18-11-16(6-7-19(18)27)32-25-17-12-21(22(36-14-23(28)29)13-20(17)30-15-31-25)33-24(35)5-4-10-34-8-2-1-3-9-34/h4-7,11-13,15,23H,1-3,8-10,14H2,(H,33,35)(H,30,31,32)	ICDUDMAKDBBZOT-UHFFFAOYSA-N	112500	US8623883, No. 6	Epidermal growth factor receptor	Homo sapiens		 9.87					7.4000	25.00 C	US Patent		10.7270/Q29885P7		aid1800296	US8623883	Fakhoury, SA; Lee, HT; Reed, JE; Schlosser, KM; Sexton, KE; Tecle, H; Winters, RT	1/7/2014	7/22/2014	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112500&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11692115	194690241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
233608	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)\C=C\CN4CCCCC4)cc23)cc1Cl	InChI=1S/C30H36ClFN6O3/c31-24-18-22(7-8-25(24)32)35-30-23-19-27(36-29(39)6-4-11-37-9-2-1-3-10-37)28(20-26(23)33-21-34-30)41-15-5-12-38-13-16-40-17-14-38/h4,6-8,18-21H,1-3,5,9-17H2,(H,36,39)(H,33,34,35)	CJIJVEOGUOJOMJ-UHFFFAOYSA-N	112501	US8623883, No. 7	Epidermal growth factor receptor	Homo sapiens		 11.35					7.4000	25.00 C	US Patent		10.7270/Q29885P7		aid1800296	US8623883	Fakhoury, SA; Lee, HT; Reed, JE; Schlosser, KM; Sexton, KE; Tecle, H; Winters, RT	1/7/2014	7/22/2014	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112501&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11721216	194690242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
233609	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCC(F)C1	InChI=1S/C24H24ClF2N5O2/c1-34-22-12-20-17(24(29-14-28-20)30-16-6-7-19(27)18(25)10-16)11-21(22)31-23(33)5-3-9-32-8-2-4-15(26)13-32/h3,5-7,10-12,14-15H,2,4,8-9,13H2,1H3,(H,31,33)(H,28,29,30)	XFXOYVZSTQCSQN-UHFFFAOYSA-N	112502	US8623883, No. 8	Epidermal growth factor receptor	Homo sapiens		 45.34					7.4000	25.00 C	US Patent		10.7270/Q29885P7		aid1800296	US8623883	Fakhoury, SA; Lee, HT; Reed, JE; Schlosser, KM; Sexton, KE; Tecle, H; Winters, RT	1/7/2014	7/22/2014	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112502&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11554905	194690243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
233610	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCC(F)CC1	InChI=1S/C24H24ClF2N5O2/c1-34-22-13-20-17(24(29-14-28-20)30-16-4-5-19(27)18(25)11-16)12-21(22)31-23(33)3-2-8-32-9-6-15(26)7-10-32/h2-5,11-15H,6-10H2,1H3,(H,31,33)(H,28,29,30)	YMQSEEOAYCTNQU-UHFFFAOYSA-N	112503	US8623883, No. 9	Epidermal growth factor receptor	Homo sapiens		 18.08					7.4000	25.00 C	US Patent		10.7270/Q29885P7		aid1800296	US8623883	Fakhoury, SA; Lee, HT; Reed, JE; Schlosser, KM; Sexton, KE; Tecle, H; Winters, RT	1/7/2014	7/22/2014	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112503&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11605533	194690244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
233611	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCCC1	InChI=1S/C25H27ClFN5O2/c1-34-23-15-21-18(25(29-16-28-21)30-17-8-9-20(27)19(26)13-17)14-22(23)31-24(33)7-6-12-32-10-4-2-3-5-11-32/h6-9,13-16H,2-5,10-12H2,1H3,(H,31,33)(H,28,29,30)	HNVQCOJZTIBBPB-UHFFFAOYSA-N	112504	US8623883, No. 10	Epidermal growth factor receptor	Homo sapiens		 12.13					7.4000	25.00 C	US Patent		10.7270/Q29885P7		aid1800296	US8623883	Fakhoury, SA; Lee, HT; Reed, JE; Schlosser, KM; Sexton, KE; Tecle, H; Winters, RT	1/7/2014	7/22/2014	Warner-Lambert	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112504&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11496734	194690245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266712	CC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C25H25BrFN5O3/c1-3-24(34)30-22-11-18-21(12-23(22)35-13-16-6-8-32(9-7-16)15(2)33)28-14-29-25(18)31-20-5-4-17(26)10-19(20)27/h3-5,10-12,14,16H,1,6-9,13H2,2H3,(H,30,34)(H,28,29,31)	UIKREWNIYFBAFO-UHFFFAOYSA-N	133685	US8846699, 1	Epidermal growth factor receptor	Homo sapiens		 3					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133685&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678540	242079819							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266713	Fc1cc(Br)ccc1Nc1ncnc2cc(OCC3CCN(CC3)C(=O)C(F)(F)F)c(NC(=O)C=C)cc12	InChI=1S/C25H22BrF4N5O3/c1-2-22(36)33-20-10-16-19(31-13-32-23(16)34-18-4-3-15(26)9-17(18)27)11-21(20)38-12-14-5-7-35(8-6-14)24(37)25(28,29)30/h2-4,9-11,13-14H,1,5-8,12H2,(H,33,36)(H,31,32,34)	UIMWWLHPSZWOBD-UHFFFAOYSA-N	133686	US8846699, 2	Epidermal growth factor receptor	Homo sapiens		 47					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133686&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678541	242079820							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266714	CS(=O)(=O)CC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C26H27BrFN5O5S/c1-3-24(34)31-22-11-18-21(29-15-30-26(18)32-20-5-4-17(27)10-19(20)28)12-23(22)38-13-16-6-8-33(9-7-16)25(35)14-39(2,36)37/h3-5,10-12,15-16H,1,6-9,13-14H2,2H3,(H,31,34)(H,29,30,32)	QOLLSSWROWSEGI-UHFFFAOYSA-N	133687	US8846699, 3	Epidermal growth factor receptor	Homo sapiens		 26					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133687&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678542	242079821							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266715	NC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C24H24BrFN6O3/c1-2-22(33)30-20-10-16-19(11-21(20)35-12-14-5-7-32(8-6-14)24(27)34)28-13-29-23(16)31-18-4-3-15(25)9-17(18)26/h2-4,9-11,13-14H,1,5-8,12H2,(H2,27,34)(H,30,33)(H,28,29,31)	JRVWLHJZBRHYIL-UHFFFAOYSA-N	133688	US8846699, 4	Epidermal growth factor receptor	Homo sapiens		 15					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133688	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133688&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678641	242079822							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266716	Fc1cc(Br)ccc1Nc1ncnc2cc(OCC3CCN(CC3)C(=O)C=C)c(NC(=O)C=C)cc12	InChI=1S/C26H25BrFN5O3/c1-3-24(34)31-22-12-18-21(29-15-30-26(18)32-20-6-5-17(27)11-19(20)28)13-23(22)36-14-16-7-9-33(10-8-16)25(35)4-2/h3-6,11-13,15-16H,1-2,7-10,14H2,(H,31,34)(H,29,30,32)	VZMZAYAKDHWCNK-UHFFFAOYSA-N	133689	US8846699, 5	Epidermal growth factor receptor	Homo sapiens		 3					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133689	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133689&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678642	242079823							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266717	Fc1cc(Br)ccc1Nc1ncnc2cc(OCc3ccncc3)c(NC(=O)C=C)cc12	InChI=1S/C23H17BrFN5O2/c1-2-22(31)29-20-10-16-19(11-21(20)32-12-14-5-7-26-8-6-14)27-13-28-23(16)30-18-4-3-15(24)9-17(18)25/h2-11,13H,1,12H2,(H,29,31)(H,27,28,30)	SNBZJZUPCUEFMH-UHFFFAOYSA-N	133690	US8846699, 6	Epidermal growth factor receptor	Homo sapiens		 56					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133690	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133690&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678643	242079824							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266718	CC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(F)c(F)c4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C25H24F3N5O3/c1-3-22(35)31-20-10-16-19(11-21(20)36-12-15-6-8-33(9-7-15)14(2)34)29-13-30-25(16)32-18-5-4-17(26)23(27)24(18)28/h3-5,10-11,13,15H,1,6-9,12H2,2H3,(H,31,35)(H,29,30,32)	CANUXFBJESAWLP-UHFFFAOYSA-N	133691	US8846699, 7	Epidermal growth factor receptor	Homo sapiens		 26					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133691	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133691&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678644	242079825							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266719	CC(=O)N1CCC(COc2cc3ncnc(Nc4c(F)cc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C25H24BrF2N5O3/c1-3-23(35)31-21-10-17-20(11-22(21)36-12-15-4-6-33(7-5-15)14(2)34)29-13-30-25(17)32-24-18(27)8-16(26)9-19(24)28/h3,8-11,13,15H,1,4-7,12H2,2H3,(H,31,35)(H,29,30,32)	MAXJTBAHZSUMAV-UHFFFAOYSA-N	133692	US8846699, 8	Epidermal growth factor receptor	Homo sapiens		 13					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133692	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133692&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678645	242079826							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266720	CCCNC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C27H30BrFN6O3/c1-3-9-30-27(37)35-10-7-17(8-11-35)15-38-24-14-22-19(13-23(24)33-25(36)4-2)26(32-16-31-22)34-21-6-5-18(28)12-20(21)29/h4-6,12-14,16-17H,2-3,7-11,15H2,1H3,(H,30,37)(H,33,36)(H,31,32,34)	OSTKLEYGNLUETG-UHFFFAOYSA-N	133693	US8846699, 9	Epidermal growth factor receptor	Homo sapiens		 36					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133693	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133693&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678646	242079827							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266721	CN(C)CC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C27H30BrFN6O3/c1-4-25(36)32-23-12-19-22(30-16-31-27(19)33-21-6-5-18(28)11-20(21)29)13-24(23)38-15-17-7-9-35(10-8-17)26(37)14-34(2)3/h4-6,11-13,16-17H,1,7-10,14-15H2,2-3H3,(H,32,36)(H,30,31,33)	RIFKDQITWFTYJS-UHFFFAOYSA-N	133694	US8846699, 10	Epidermal growth factor receptor	Homo sapiens		 6					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133694	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133694&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678751	242079828							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266722	CC(C)(C)NC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C28H32BrFN6O3/c1-5-25(37)33-23-13-19-22(31-16-32-26(19)34-21-7-6-18(29)12-20(21)30)14-24(23)39-15-17-8-10-36(11-9-17)27(38)35-28(2,3)4/h5-7,12-14,16-17H,1,8-11,15H2,2-4H3,(H,33,37)(H,35,38)(H,31,32,34)	SFSSJAHDZCXDRO-UHFFFAOYSA-N	133695	US8846699, 11	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133695	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133695&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678752	242079829							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266723	CN(C)CC(=O)NCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H26BrFN6O3/c1-4-22(33)30-20-11-16-19(12-21(20)35-9-5-8-27-23(34)13-32(2)3)28-14-29-24(16)31-18-7-6-15(25)10-17(18)26/h4,6-7,10-12,14H,1,5,8-9,13H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	SUPFKVRCENJLNR-UHFFFAOYSA-N	133696	US8846699, 12	Epidermal growth factor receptor	Homo sapiens		 2					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133696	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133696&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678753	242079830							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266724	CC(=O)NCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O3/c1-3-21(31)28-19-10-15-18(11-20(19)32-8-4-7-25-13(2)30)26-12-27-22(15)29-17-6-5-14(23)9-16(17)24/h3,5-6,9-12H,1,4,7-8H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	DTNINSLBWVYZJC-UHFFFAOYSA-N	133697	US8846699, 13	Epidermal growth factor receptor	Homo sapiens		 4					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133697	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133697&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678754	242079831							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266725	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCCNC(=O)C(F)(F)F)c(NC(=O)C=C)cc12	InChI=1S/C22H18BrF4N5O3/c1-2-19(33)31-17-9-13-16(10-18(17)35-7-3-6-28-21(34)22(25,26)27)29-11-30-20(13)32-15-5-4-12(23)8-14(15)24/h2,4-5,8-11H,1,3,6-7H2,(H,28,34)(H,31,33)(H,29,30,32)	RVHJFVOVALAVIJ-UHFFFAOYSA-N	133698	US8846699, 14	Epidermal growth factor receptor	Homo sapiens		 59					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133698	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133698&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678755	242079832							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266726	CS(=O)(=O)CC(=O)NCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrFN5O5S/c1-3-21(31)29-19-10-15-18(11-20(19)35-8-4-7-26-22(32)12-36(2,33)34)27-13-28-23(15)30-17-6-5-14(24)9-16(17)25/h3,5-6,9-11,13H,1,4,7-8,12H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	AZWGHQIJMYOUGY-UHFFFAOYSA-N	133699	US8846699, 15	Epidermal growth factor receptor	Homo sapiens		 68					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133699	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133699&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678756	242079833							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266727	CCNC(=O)NCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H24BrFN6O3/c1-3-21(32)30-19-11-15-18(12-20(19)34-9-5-8-27-23(33)26-4-2)28-13-29-22(15)31-17-7-6-14(24)10-16(17)25/h3,6-7,10-13H,1,4-5,8-9H2,2H3,(H,30,32)(H2,26,27,33)(H,28,29,31)	RWZGZLPZVJTIAS-UHFFFAOYSA-N	133700	US8846699, 16	Epidermal growth factor receptor	Homo sapiens		 11					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133700	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133700&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678855	242079834							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266728	CNCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H21BrFN5O2/c1-3-20(29)27-18-10-14-17(11-19(18)30-8-4-7-24-2)25-12-26-21(14)28-16-6-5-13(22)9-15(16)23/h3,5-6,9-12,24H,1,4,7-8H2,2H3,(H,27,29)(H,25,26,28)	NFWFBDDHXYCYHP-UHFFFAOYSA-N	133701	US8846699, 17	Epidermal growth factor receptor	Homo sapiens		 3					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133701&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678856	242079835							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266729	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H19BrFN5O3/c1-3-20(30)27-18-9-14-17(10-19(18)31-7-6-24-12(2)29)25-11-26-21(14)28-16-5-4-13(22)8-15(16)23/h3-5,8-11H,1,6-7H2,2H3,(H,24,29)(H,27,30)(H,25,26,28)	BTYFROXGYQVTDB-UHFFFAOYSA-N	133702	US8846699, 18	Epidermal growth factor receptor	Homo sapiens		 2					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133702&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678857	242079836							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266730	CN(C)CCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H21BrFN5O2/c1-4-20(29)26-18-10-14-17(11-19(18)30-8-7-28(2)3)24-12-25-21(14)27-16-6-5-13(22)9-15(16)23/h4-6,9-12H,1,7-8H2,2-3H3,(H,26,29)(H,24,25,27)	FZPKPBLYVQTKPP-UHFFFAOYSA-N	133703	US8846699, 19	Epidermal growth factor receptor	Homo sapiens		 9					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133703	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133703&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678858	242079837							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266731	CC(=O)NCCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrFN5O3/c1-3-22(32)29-20-11-16-19(12-21(20)33-9-5-4-8-26-14(2)31)27-13-28-23(16)30-18-7-6-15(24)10-17(18)25/h3,6-7,10-13H,1,4-5,8-9H2,2H3,(H,26,31)(H,29,32)(H,27,28,30)	RWBZRZZVHCQBPV-UHFFFAOYSA-N	133704	US8846699, 20	Epidermal growth factor receptor	Homo sapiens		 10					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133704	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133704&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678859	242079838							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266732	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)C3CC3)c(NC(=O)C=C)cc12	InChI=1S/C23H21BrFN5O3/c1-2-21(31)29-19-10-15-18(11-20(19)33-8-7-26-23(32)13-3-4-13)27-12-28-22(15)30-17-6-5-14(24)9-16(17)25/h2,5-6,9-13H,1,3-4,7-8H2,(H,26,32)(H,29,31)(H,27,28,30)	KDCWCHYNUNBAEU-UHFFFAOYSA-N	133705	US8846699, 21	Epidermal growth factor receptor	Homo sapiens		 8					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133705&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678860	242079839							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266733	FC(F)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H17BrF3N5O3/c1-2-18(31)29-16-8-12-15(9-17(16)33-6-5-26-21(32)19(24)25)27-10-28-20(12)30-14-4-3-11(22)7-13(14)23/h2-4,7-10,19H,1,5-6H2,(H,26,32)(H,29,31)(H,27,28,30)	BDGBUNQPUJHMAM-UHFFFAOYSA-N	133706	US8846699, 22	Epidermal growth factor receptor	Homo sapiens		 5					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133706	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133706&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678861	242079840							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266734	CCNC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H22BrFN6O3/c1-3-20(31)29-18-10-14-17(11-19(18)33-8-7-26-22(32)25-4-2)27-12-28-21(14)30-16-6-5-13(23)9-15(16)24/h3,5-6,9-12H,1,4,7-8H2,2H3,(H,29,31)(H2,25,26,32)(H,27,28,30)	FFMVKPOWYKTXJH-UHFFFAOYSA-N	133707	US8846699, 23	Epidermal growth factor receptor	Homo sapiens		 2					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133707	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133707&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678954	242079841							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266735	NC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C20H18BrFN6O3/c1-2-18(29)27-16-8-12-15(9-17(16)31-6-5-24-20(23)30)25-10-26-19(12)28-14-4-3-11(21)7-13(14)22/h2-4,7-10H,1,5-6H2,(H,27,29)(H3,23,24,30)(H,25,26,28)	YMDWARQKAFASNA-UHFFFAOYSA-N	133708	US8846699, 24	Epidermal growth factor receptor	Homo sapiens		 4					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133708	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133708&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678955	242079842							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266736	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H24BrFN6O3/c1-4-21(32)29-19-10-15-18(11-20(19)34-8-7-26-22(33)12-31(2)3)27-13-28-23(15)30-17-6-5-14(24)9-16(17)25/h4-6,9-11,13H,1,7-8,12H2,2-3H3,(H,26,33)(H,29,32)(H,27,28,30)	SOYOGGAXHRNJSO-UHFFFAOYSA-N	133709	US8846699, 25	Epidermal growth factor receptor	Homo sapiens		 2					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133709	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133709&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678956	242079843							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266737	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)C=C)c(NC(=O)C=C)cc12	InChI=1S/C22H19BrFN5O3/c1-3-20(30)25-7-8-32-19-11-17-14(10-18(19)28-21(31)4-2)22(27-12-26-17)29-16-6-5-13(23)9-15(16)24/h3-6,9-12H,1-2,7-8H2,(H,25,30)(H,28,31)(H,26,27,29)	YOHNLHXVSFTRLR-UHFFFAOYSA-N	133710	US8846699, 26	Epidermal growth factor receptor	Homo sapiens		 5					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133710	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133710&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678957	242079844							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266738	CC(=O)CNCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O3/c1-3-21(31)28-19-9-15-18(10-20(19)32-7-6-25-11-13(2)30)26-12-27-22(15)29-17-5-4-14(23)8-16(17)24/h3-5,8-10,12,25H,1,6-7,11H2,2H3,(H,28,31)(H,26,27,29)	BJQOPTDJQILKBE-UHFFFAOYSA-N	133711	US8846699, 55::US8846699, 27	Epidermal growth factor receptor	Homo sapiens		 3					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133711	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133711&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679448	242079845							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266739	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)C(F)(F)F)c(NC(=O)C=C)cc12	InChI=1S/C21H16BrF4N5O3/c1-2-18(32)30-16-8-12-15(9-17(16)34-6-5-27-20(33)21(24,25)26)28-10-29-19(12)31-14-4-3-11(22)7-13(14)23/h2-4,7-10H,1,5-6H2,(H,27,33)(H,30,32)(H,28,29,31)	CRPONWBREIIKIJ-UHFFFAOYSA-N	133712	US8846699, 28	Epidermal growth factor receptor	Homo sapiens		 23					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133712	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133712&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678959	242079846							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266740	NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C19H17BrFN5O2/c1-2-18(27)25-16-8-12-15(9-17(16)28-6-5-22)23-10-24-19(12)26-14-4-3-11(20)7-13(14)21/h2-4,7-10H,1,5-6,22H2,(H,25,27)(H,23,24,26)	RZLHXVSQWOPUOD-UHFFFAOYSA-N	133713	US8846699, 29	Epidermal growth factor receptor	Homo sapiens		 4					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133713	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133713&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678960	242079847							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266741	CNCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C20H19BrFN5O2/c1-3-19(28)26-17-9-13-16(10-18(17)29-7-6-23-2)24-11-25-20(13)27-15-5-4-12(21)8-14(15)22/h3-5,8-11,23H,1,6-7H2,2H3,(H,26,28)(H,24,25,27)	XCGXIKJHGROCJB-UHFFFAOYSA-N	133714	US8846699, 30	Epidermal growth factor receptor	Homo sapiens		 96					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133714	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133714&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679051	242079848							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266742	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCC=C)c(NC(=O)C=C)cc12	InChI=1S/C21H18BrFN4O2/c1-3-5-8-29-19-11-17-14(10-18(19)26-20(28)4-2)21(25-12-24-17)27-16-7-6-13(22)9-15(16)23/h3-4,6-7,9-12H,1-2,5,8H2,(H,26,28)(H,24,25,27)	DDQQLDVFRBXYBU-UHFFFAOYSA-N	133715	US8846699, 31	Epidermal growth factor receptor	Homo sapiens		 90					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133715	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133715&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679052	242079849							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266743	COCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C20H18BrFN4O3/c1-3-19(27)25-17-9-13-16(10-18(17)29-7-6-28-2)23-11-24-20(13)26-15-5-4-12(21)8-14(15)22/h3-5,8-11H,1,6-7H2,2H3,(H,25,27)(H,23,24,26)	UJQBDJHFABZCBZ-UHFFFAOYSA-N	133716	US8846699, 32	Epidermal growth factor receptor	Homo sapiens		 25					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133716	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133716&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679053	242079850							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266744	CS(=O)(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C20H19BrFN5O4S/c1-3-19(28)26-17-9-13-16(10-18(17)31-7-6-25-32(2,29)30)23-11-24-20(13)27-15-5-4-12(21)8-14(15)22/h3-5,8-11,25H,1,6-7H2,2H3,(H,26,28)(H,23,24,27)	RHPPSEKINPIOTC-UHFFFAOYSA-N	133717	US8846699, 33	Epidermal growth factor receptor	Homo sapiens		 25					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133717&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679054	242079851							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266745	CCCNC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H24BrFN6O3/c1-3-7-26-23(33)27-8-9-34-20-12-18-15(11-19(20)30-21(32)4-2)22(29-13-28-18)31-17-6-5-14(24)10-16(17)25/h4-6,10-13H,2-3,7-9H2,1H3,(H,30,32)(H2,26,27,33)(H,28,29,31)	PFRACGZLZAHSRL-UHFFFAOYSA-N	133718	US8846699, 34	Epidermal growth factor receptor	Homo sapiens		 26					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133718	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133718&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679055	242079852							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266746	CNC(=S)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H20BrFN6O2S/c1-3-19(30)28-17-9-13-16(10-18(17)31-7-6-25-21(32)24-2)26-11-27-20(13)29-15-5-4-12(22)8-14(15)23/h3-5,8-11H,1,6-7H2,2H3,(H,28,30)(H2,24,25,32)(H,26,27,29)	NCWOITZVEWWDCD-UHFFFAOYSA-N	133719	US8846699, 35	Epidermal growth factor receptor	Homo sapiens		 98					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133719	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133719&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679056	242079853							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266747	CCNC(=S)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H22BrFN6O2S/c1-3-20(31)29-18-10-14-17(11-19(18)32-8-7-26-22(33)25-4-2)27-12-28-21(14)30-16-6-5-13(23)9-15(16)24/h3,5-6,9-12H,1,4,7-8H2,2H3,(H,29,31)(H2,25,26,33)(H,27,28,30)	BNKGZNXIORHJHK-UHFFFAOYSA-N	133720	US8846699, 36	Epidermal growth factor receptor	Homo sapiens		 91					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133720	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133720&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679057	242079854							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266748	CC(C)NC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H24BrFN6O3/c1-4-21(32)30-19-10-15-18(11-20(19)34-8-7-26-23(33)29-13(2)3)27-12-28-22(15)31-17-6-5-14(24)9-16(17)25/h4-6,9-13H,1,7-8H2,2-3H3,(H,30,32)(H2,26,29,33)(H,27,28,31)	ZRODGYIOYZYWNC-UHFFFAOYSA-N	133721	US8846699, 37	Epidermal growth factor receptor	Homo sapiens		 36					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133721	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133721&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679149	242079855							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266749	CCC(C)NC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H26BrFN6O3/c1-4-14(3)30-24(34)27-8-9-35-21-12-19-16(11-20(21)31-22(33)5-2)23(29-13-28-19)32-18-7-6-15(25)10-17(18)26/h5-7,10-14H,2,4,8-9H2,1,3H3,(H,31,33)(H2,27,30,34)(H,28,29,32)	QIAQUEWCLIWXJA-UHFFFAOYSA-N	133722	US8846699, 38	Epidermal growth factor receptor	Homo sapiens		 20					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133722	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133722&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679150	242079856							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266750	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)NC=C)c(NC(=O)C=C)cc12	InChI=1S/C22H20BrFN6O3/c1-3-20(31)29-18-10-14-17(11-19(18)33-8-7-26-22(32)25-4-2)27-12-28-21(14)30-16-6-5-13(23)9-15(16)24/h3-6,9-12H,1-2,7-8H2,(H,29,31)(H2,25,26,32)(H,27,28,30)	RLISPUUHADIREB-UHFFFAOYSA-N	133723	US8846699, 39	Epidermal growth factor receptor	Homo sapiens		 29					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133723	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133723&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679151	242079857							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266751	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)NCC=C)c(NC(=O)C=C)cc12	InChI=1S/C23H22BrFN6O3/c1-3-7-26-23(33)27-8-9-34-20-12-18-15(11-19(20)30-21(32)4-2)22(29-13-28-18)31-17-6-5-14(24)10-16(17)25/h3-6,10-13H,1-2,7-9H2,(H,30,32)(H2,26,27,33)(H,28,29,31)	YNLXJJCFNYBGEB-UHFFFAOYSA-N	133724	US8846699, 40	Epidermal growth factor receptor	Homo sapiens		 19					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133724	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133724&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679152	242079858							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266752	Fc1c(Cl)c(Br)ccc1Nc1ncnc2cc(OCCNC(=O)N3CCOCC3)c(NC(=O)C=C)cc12	InChI=1S/C24H23BrClFN6O4/c1-2-20(34)31-18-11-14-17(12-19(18)37-8-5-28-24(35)33-6-9-36-10-7-33)29-13-30-23(14)32-16-4-3-15(25)21(26)22(16)27/h2-4,11-13H,1,5-10H2,(H,28,35)(H,31,34)(H,29,30,32)	MTPCBGCWGDTUPD-UHFFFAOYSA-N	133725	US8846699, 41	Epidermal growth factor receptor	Homo sapiens		 35					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133725	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133725&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679153	242079859							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266753	CN(CCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)C(C)=O	InChI=1S/C22H21BrFN5O3/c1-4-21(31)27-19-10-15-18(11-20(19)32-8-7-29(3)13(2)30)25-12-26-22(15)28-17-6-5-14(23)9-16(17)24/h4-6,9-12H,1,7-8H2,2-3H3,(H,27,31)(H,25,26,28)	HFPYKICVHQECPZ-UHFFFAOYSA-N	133726	US8846699, 42	Epidermal growth factor receptor	Homo sapiens		 59					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133726	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133726&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679154	242079860							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266754	CC(=O)NCCSc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H19BrFN5O2S/c1-3-20(30)27-18-9-14-17(10-19(18)31-7-6-24-12(2)29)25-11-26-21(14)28-16-5-4-13(22)8-15(16)23/h3-5,8-11H,1,6-7H2,2H3,(H,24,29)(H,27,30)(H,25,26,28)	RLCCESPCQUPJAN-UHFFFAOYSA-N	133727	US8846699, 43	Epidermal growth factor receptor	Homo sapiens		 109					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133727	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133727&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679247	242079861							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266755	COCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O4/c1-3-20(30)28-18-9-14-17(10-19(18)33-7-6-25-21(31)11-32-2)26-12-27-22(14)29-16-5-4-13(23)8-15(16)24/h3-5,8-10,12H,1,6-7,11H2,2H3,(H,25,31)(H,28,30)(H,26,27,29)	COTCOYMOTSGNJY-UHFFFAOYSA-N	133728	US8846699, 44	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133728	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133728&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679248	242079862							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266756	OCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H19BrFN5O4/c1-2-19(30)27-17-8-13-16(9-18(17)32-6-5-24-20(31)10-29)25-11-26-21(13)28-15-4-3-12(22)7-14(15)23/h2-4,7-9,11,29H,1,5-6,10H2,(H,24,31)(H,27,30)(H,25,26,28)	AVWUQSBIDMSXKK-UHFFFAOYSA-N	133729	US8846699, 45	Epidermal growth factor receptor	Homo sapiens		 32					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133729	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133729&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679249	242079863							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266757	CSCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O3S/c1-3-20(30)28-18-9-14-17(10-19(18)32-7-6-25-21(31)11-33-2)26-12-27-22(14)29-16-5-4-13(23)8-15(16)24/h3-5,8-10,12H,1,6-7,11H2,2H3,(H,25,31)(H,28,30)(H,26,27,29)	RFLCMWQKNNQDPU-UHFFFAOYSA-N	133730	US8846699, 46	Epidermal growth factor receptor	Homo sapiens		 39					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133730	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133730&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679250	242079864							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266758	CS(=O)(=O)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O5S/c1-3-20(30)28-18-9-14-17(10-19(18)34-7-6-25-21(31)11-35(2,32)33)26-12-27-22(14)29-16-5-4-13(23)8-15(16)24/h3-5,8-10,12H,1,6-7,11H2,2H3,(H,25,31)(H,28,30)(H,26,27,29)	UNFSZGKSDKZSHK-UHFFFAOYSA-N	133731	US8846699, 47	Epidermal growth factor receptor	Homo sapiens		 24					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133731	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133731&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679251	242079865							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266759	CC(C)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrFN5O3/c1-4-21(31)29-19-10-15-18(11-20(19)33-8-7-26-23(32)13(2)3)27-12-28-22(15)30-17-6-5-14(24)9-16(17)25/h4-6,9-13H,1,7-8H2,2-3H3,(H,26,32)(H,29,31)(H,27,28,30)	ODIVICGOEIOVIQ-UHFFFAOYSA-N	133732	US8846699, 48	Epidermal growth factor receptor	Homo sapiens		 128					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133732	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133732&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679252	242079866							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266760	CC(=C)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H21BrFN5O3/c1-4-21(31)29-19-10-15-18(11-20(19)33-8-7-26-23(32)13(2)3)27-12-28-22(15)30-17-6-5-14(24)9-16(17)25/h4-6,9-12H,1-2,7-8H2,3H3,(H,26,32)(H,29,31)(H,27,28,30)	XAISGNDPHUTFTD-UHFFFAOYSA-N	133733	US8846699, 49	Epidermal growth factor receptor	Homo sapiens		 69					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133733	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133733&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679253	242079867							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266761	CC=CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C |w:1.0|	InChI=1S/C23H21BrFN5O3/c1-3-5-22(32)26-8-9-33-20-12-18-15(11-19(20)29-21(31)4-2)23(28-13-27-18)30-17-7-6-14(24)10-16(17)25/h3-7,10-13H,2,8-9H2,1H3,(H,26,32)(H,29,31)(H,27,28,30)	AYCVHMDIHRQBDR-UHFFFAOYSA-N	133734	US8846699, 50	Epidermal growth factor receptor	Homo sapiens		 19					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133734	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133734&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679354	242079868							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266762	CCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrFN5O3/c1-3-5-22(32)26-8-9-33-20-12-18-15(11-19(20)29-21(31)4-2)23(28-13-27-18)30-17-7-6-14(24)10-16(17)25/h4,6-7,10-13H,2-3,5,8-9H2,1H3,(H,26,32)(H,29,31)(H,27,28,30)	LAJAGNNRQYMPDT-UHFFFAOYSA-N	133735	US8846699, 51	Epidermal growth factor receptor	Homo sapiens		 32					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133735&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679355	242079869							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266763	CCC=CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C |w:3.3|	InChI=1S/C24H23BrFN5O3/c1-3-5-6-23(33)27-9-10-34-21-13-19-16(12-20(21)30-22(32)4-2)24(29-14-28-19)31-18-8-7-15(25)11-17(18)26/h4-8,11-14H,2-3,9-10H2,1H3,(H,27,33)(H,30,32)(H,28,29,31)	PGZSGIRUWAIJMW-UHFFFAOYSA-N	133736	US8846699, 52	Epidermal growth factor receptor	Homo sapiens		 36					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133736	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133736&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679356	242079870							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266764	CN(C)CC=CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C |w:5.5|	InChI=1S/C25H26BrFN6O3/c1-4-23(34)31-21-13-17-20(14-22(21)36-11-9-28-24(35)6-5-10-33(2)3)29-15-30-25(17)32-19-8-7-16(26)12-18(19)27/h4-8,12-15H,1,9-11H2,2-3H3,(H,28,35)(H,31,34)(H,29,30,32)	RBVDARIRGNJNFG-UHFFFAOYSA-N	133737	US8846699, 53	Epidermal growth factor receptor	Homo sapiens		 16					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133737	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133737&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679357	242079871							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266765	CC(C)(C)NC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C24H25BrClFN6O3/c1-5-19(34)31-17-10-13-16(11-18(17)36-9-8-28-23(35)33-24(2,3)4)29-12-30-22(13)32-15-7-6-14(25)20(26)21(15)27/h5-7,10-12H,1,8-9H2,2-4H3,(H,31,34)(H2,28,33,35)(H,29,30,32)	VNJIDIZIWFGYFN-UHFFFAOYSA-N	133738	US8846699, 54	Epidermal growth factor receptor	Homo sapiens		 45					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133738	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133738&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679358	242079872							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266766	CCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O3/c1-3-20(30)25-7-8-32-19-11-17-14(10-18(19)28-21(31)4-2)22(27-12-26-17)29-16-6-5-13(23)9-15(16)24/h4-6,9-12H,2-3,7-8H2,1H3,(H,25,30)(H,28,31)(H,26,27,29)	CUKHNNMXTRUTGY-UHFFFAOYSA-N	18662	US8846699, 55	Epidermal growth factor receptor	Homo sapiens		 589					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18662&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678958	249493541							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266767	CCN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H26BrFN6O3/c1-4-22(33)30-20-11-16-19(12-21(20)35-9-8-27-23(34)13-32(3)5-2)28-14-29-24(16)31-18-7-6-15(25)10-17(18)26/h4,6-7,10-12,14H,1,5,8-9,13H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	KBHOZTNSGNVWQF-UHFFFAOYSA-N	133740	US8846699, 56	Epidermal growth factor receptor	Homo sapiens		 198					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133740	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133740&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679449	242079873							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266768	NCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H20BrFN6O3/c1-2-19(30)28-17-8-13-16(9-18(17)32-6-5-25-20(31)10-24)26-11-27-21(13)29-15-4-3-12(22)7-14(15)23/h2-4,7-9,11H,1,5-6,10,24H2,(H,25,31)(H,28,30)(H,26,27,29)	RHNPQUDHHOMHDW-UHFFFAOYSA-N	133741	US8846699, 57	Epidermal growth factor receptor	Homo sapiens		 89					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133741	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133741&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679450	242079874							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266769	CC(N(C)C)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H26BrFN6O3/c1-5-22(33)30-20-11-16-19(12-21(20)35-9-8-27-24(34)14(2)32(3)4)28-13-29-23(16)31-18-7-6-15(25)10-17(18)26/h5-7,10-14H,1,8-9H2,2-4H3,(H,27,34)(H,30,33)(H,28,29,31)	FROYTOQPRFQLJH-UHFFFAOYSA-N	133742	US8846699, 58	Epidermal growth factor receptor	Homo sapiens		 125					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133742	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133742&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679451	242079875							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266770	CCN(CC)CCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C26H30BrFN6O3/c1-4-24(35)32-22-14-18-21(30-16-31-26(18)33-20-8-7-17(27)13-19(20)28)15-23(22)37-12-10-29-25(36)9-11-34(5-2)6-3/h4,7-8,13-16H,1,5-6,9-12H2,2-3H3,(H,29,36)(H,32,35)(H,30,31,33)	YJTSMQVXARPZGP-UHFFFAOYSA-N	133743	US8846699, 59	Epidermal growth factor receptor	Homo sapiens		 44					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133743	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133743&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679452	242079876							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266771	CNCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H22BrFN6O3/c1-3-20(31)29-18-9-14-17(10-19(18)33-7-6-26-21(32)11-25-2)27-12-28-22(14)30-16-5-4-13(23)8-15(16)24/h3-5,8-10,12,25H,1,6-7,11H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	OZCTZZBPWFFISD-UHFFFAOYSA-N	133744	US8846699, 60	Epidermal growth factor receptor	Homo sapiens		 136					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133744	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133744&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679453	242079877							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266772	CN(C)CCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H26BrFN6O3/c1-4-22(33)30-20-12-16-19(13-21(20)35-10-8-27-23(34)7-9-32(2)3)28-14-29-24(16)31-18-6-5-15(25)11-17(18)26/h4-6,11-14H,1,7-10H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	YLOOVLOMQTYREV-UHFFFAOYSA-N	133745	US8846699, 61	Epidermal growth factor receptor	Homo sapiens		 9					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133745	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133745&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16066678	242079878							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266773	NCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H22BrFN6O3/c1-2-20(31)29-18-10-14-17(11-19(18)33-8-7-26-21(32)5-6-25)27-12-28-22(14)30-16-4-3-13(23)9-15(16)24/h2-4,9-12H,1,5-8,25H2,(H,26,32)(H,29,31)(H,27,28,30)	HXCZCEAQVPKCAF-UHFFFAOYSA-N	133746	US8846699, 62	Epidermal growth factor receptor	Homo sapiens		 258					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133746	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133746&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679546	242079879							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266774	COC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H19BrFN5O4/c1-3-19(29)27-17-9-13-16(10-18(17)32-7-6-24-21(30)31-2)25-11-26-20(13)28-15-5-4-12(22)8-14(15)23/h3-5,8-11H,1,6-7H2,2H3,(H,24,30)(H,27,29)(H,25,26,28)	GUFBSFFWXVLWCF-UHFFFAOYSA-N	133747	US8846699, 63	Epidermal growth factor receptor	Homo sapiens		 158					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133747&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679547	242079880							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266775	COCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrFN5O4/c1-3-21(31)29-19-11-15-18(12-20(19)34-9-7-26-22(32)6-8-33-2)27-13-28-23(15)30-17-5-4-14(24)10-16(17)25/h3-5,10-13H,1,6-9H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	MHPAMQNXZMJMLZ-UHFFFAOYSA-N	133748	US8846699, 64	Epidermal growth factor receptor	Homo sapiens		 70					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133748	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133748&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679548	242079881							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266776	CCN(CC)CCNC(=O)COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H28BrFN6O3/c1-4-23(34)31-21-12-17-20(13-22(21)36-14-24(35)28-9-10-33(5-2)6-3)29-15-30-25(17)32-19-8-7-16(26)11-18(19)27/h4,7-8,11-13,15H,1,5-6,9-10,14H2,2-3H3,(H,28,35)(H,31,34)(H,29,30,32)	JLWNHWBYVLABOU-UHFFFAOYSA-N	133749	US8846699, 65	Epidermal growth factor receptor	Homo sapiens		 652					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133749	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133749&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679549	242079882							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266777	CN(C)CCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H28BrFN6O3/c1-4-23(34)31-21-13-17-20(14-22(21)36-11-9-28-24(35)6-5-10-33(2)3)29-15-30-25(17)32-19-8-7-16(26)12-18(19)27/h4,7-8,12-15H,1,5-6,9-11H2,2-3H3,(H,28,35)(H,31,34)(H,29,30,32)	VWJOQIGDVVMABO-UHFFFAOYSA-N	133750	US8846699, 66	Epidermal growth factor receptor	Homo sapiens		 21					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133750&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679550	242079883							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266778	OCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O4/c1-2-20(31)28-18-10-14-17(11-19(18)33-8-6-25-21(32)5-7-30)26-12-27-22(14)29-16-4-3-13(23)9-15(16)24/h2-4,9-12,30H,1,5-8H2,(H,25,32)(H,28,31)(H,26,27,29)	ANFPFYSQIJYLHA-UHFFFAOYSA-N	133751	US8846699, 67	Epidermal growth factor receptor	Homo sapiens		 89					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133751	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133751&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679551	242079884							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266779	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(F)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H24F2N6O3/c1-4-21(32)29-19-10-15-18(11-20(19)34-8-7-26-22(33)12-31(2)3)27-13-28-23(15)30-17-6-5-14(24)9-16(17)25/h4-6,9-11,13H,1,7-8,12H2,2-3H3,(H,26,33)(H,29,32)(H,27,28,30)	UGQFWYMJDDLZLM-UHFFFAOYSA-N	133752	US8846699, 68	Epidermal growth factor receptor	Homo sapiens		 156					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133752	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133752&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679637	242079885							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266780	CCOC(=O)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H21BrFN5O5/c1-3-20(31)29-18-10-14-17(11-19(18)35-8-7-26-22(32)23(33)34-4-2)27-12-28-21(14)30-16-6-5-13(24)9-15(16)25/h3,5-6,9-12H,1,4,7-8H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	QEWGTHVMSDULHL-UHFFFAOYSA-N	133753	US8846699, 71	Epidermal growth factor receptor	Homo sapiens		 98					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133753	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133753&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100338	242079886							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266781	OC(=O)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H17BrFN5O5/c1-2-18(29)27-16-8-12-15(9-17(16)33-6-5-24-20(30)21(31)32)25-10-26-19(12)28-14-4-3-11(22)7-13(14)23/h2-4,7-10H,1,5-6H2,(H,24,30)(H,27,29)(H,31,32)(H,25,26,28)	WTKHKEHPGMXSBH-UHFFFAOYSA-N	133754	US8846699, 72	Epidermal growth factor receptor	Homo sapiens		 102					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133754	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133754&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101091	242079887							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266782	CON=CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C |w:3.3|	InChI=1S/C22H20BrFN6O4/c1-3-20(31)29-18-9-14-17(10-19(18)34-7-6-25-21(32)11-28-33-2)26-12-27-22(14)30-16-5-4-13(23)8-15(16)24/h3-5,8-12H,1,6-7H2,2H3,(H,25,32)(H,29,31)(H,26,27,30)	CVUZHHCFPFIVKB-UHFFFAOYSA-N	133755	US8846699, 73	Epidermal growth factor receptor	Homo sapiens		 256					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133755	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133755&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679638	242079888							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266783	CC(CN(C)C)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H28BrFN6O3/c1-5-23(34)31-21-11-17-20(12-22(21)36-9-8-28-25(35)15(2)13-33(3)4)29-14-30-24(17)32-19-7-6-16(26)10-18(19)27/h5-7,10-12,14-15H,1,8-9,13H2,2-4H3,(H,28,35)(H,31,34)(H,29,30,32)	HEYAJCDUBCQMPG-UHFFFAOYSA-N	133756	US8846699, 74	Epidermal growth factor receptor	Homo sapiens		 251					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133756	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133756&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679639	242079889							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266784	CC(CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)N(C)C	InChI=1S/C25H28BrFN6O3/c1-5-23(34)31-21-12-17-20(13-22(21)36-9-8-28-24(35)10-15(2)33(3)4)29-14-30-25(17)32-19-7-6-16(26)11-18(19)27/h5-7,11-15H,1,8-10H2,2-4H3,(H,28,35)(H,31,34)(H,29,30,32)	AVINRNFZBJEYNB-UHFFFAOYSA-N	133757	US8846699, 75	Epidermal growth factor receptor	Homo sapiens		 325					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133757	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133757&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679640	242079890							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266785	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C(C)=C	InChI=1S/C22H21BrFN5O3/c1-12(2)22(31)29-19-9-15-18(10-20(19)32-7-6-25-13(3)30)26-11-27-21(15)28-17-5-4-14(23)8-16(17)24/h4-5,8-11H,1,6-7H2,2-3H3,(H,25,30)(H,29,31)(H,26,27,28)	UQBFLJPRNOOVSR-UHFFFAOYSA-N	133758	US8846699, 76	Epidermal growth factor receptor	Homo sapiens		 1020					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133758	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133758&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679641	242079891							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266786	CCC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(C)=O	InChI=1S/C21H21BrFN5O3/c1-3-20(30)27-18-9-14-17(10-19(18)31-7-6-24-12(2)29)25-11-26-21(14)28-16-5-4-13(22)8-15(16)23/h4-5,8-11H,3,6-7H2,1-2H3,(H,24,29)(H,27,30)(H,25,26,28)	FUDZVMAAPBVLTJ-UHFFFAOYSA-N	133759	US8846699, 77	Epidermal growth factor receptor	Homo sapiens		 866					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133759	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133759&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16679642	242079892							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266787	CN(C(=O)C=C)c1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(C)=O	InChI=1S/C22H21BrFN5O3/c1-4-21(31)29(3)19-10-15-18(11-20(19)32-8-7-25-13(2)30)26-12-27-22(15)28-17-6-5-14(23)9-16(17)24/h4-6,9-12H,1,7-8H2,2-3H3,(H,25,30)(H,26,27,28)	LQZIDSSLBIXXRD-UHFFFAOYSA-N	133760	US8846699, 78	Epidermal growth factor receptor	Homo sapiens		 389					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133760	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133760&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678147	242079893							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266788	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(F)c3)c2cc1NC(=O)C=C	InChI=1S/C23H24BrFN6O3/c1-4-21(32)30-19-10-15-18(11-20(19)34-8-7-26-22(33)12-31(2)3)27-13-28-23(15)29-14-5-6-16(24)17(25)9-14/h4-6,9-11,13H,1,7-8,12H2,2-3H3,(H,26,33)(H,30,32)(H,27,28,29)	RIGSMDFVBGSWIZ-UHFFFAOYSA-N	133761	US8846699, 79	Epidermal growth factor receptor	Homo sapiens		 78					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133761	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133761&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678148	242079894							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266789	CC(CNC(C)=O)Oc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrFN5O3/c1-4-21(31)28-19-8-15-18(9-20(19)32-12(2)10-25-13(3)30)26-11-27-22(15)29-17-6-5-14(23)7-16(17)24/h4-9,11-12H,1,10H2,2-3H3,(H,25,30)(H,28,31)(H,26,27,29)	QEEAABFVJCOYPN-UHFFFAOYSA-N	133762	US8846699, 80	Epidermal growth factor receptor	Homo sapiens		 36					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133762	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133762&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678149	242079895							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266790	CC(COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)NC(C)=O	InChI=1S/C22H21BrFN5O3/c1-4-21(31)28-19-8-15-18(9-20(19)32-10-12(2)27-13(3)30)25-11-26-22(15)29-17-6-5-14(23)7-16(17)24/h4-9,11-12H,1,10H2,2-3H3,(H,27,30)(H,28,31)(H,25,26,29)	AXWQPHKBZRUJSS-UHFFFAOYSA-N	133763	US8846699, 81	Epidermal growth factor receptor	Homo sapiens		 154					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133763	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133763&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678150	242079896							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266791	C[C@H](COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)NC(C)=O	InChI=1S/C22H21BrFN5O3/c1-4-21(31)28-19-8-15-18(9-20(19)32-10-12(2)27-13(3)30)25-11-26-22(15)29-17-6-5-14(23)7-16(17)24/h4-9,11-12H,1,10H2,2-3H3,(H,27,30)(H,28,31)(H,25,26,29)	AXWQPHKBZRUJSS-UHFFFAOYSA-N	133764	US8846699, 82	Epidermal growth factor receptor	Homo sapiens		 29					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133764&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678151	242079897							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266792	C[C@@H](COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)NC(C)=O	InChI=1S/C22H21BrFN5O3/c1-4-21(31)28-19-8-15-18(9-20(19)32-10-12(2)27-13(3)30)25-11-26-22(15)29-17-6-5-14(23)7-16(17)24/h4-9,11-12H,1,10H2,2-3H3,(H,27,30)(H,28,31)(H,25,26,29)	AXWQPHKBZRUJSS-UHFFFAOYSA-N	133765	US8846699, 83	Epidermal growth factor receptor	Homo sapiens		 98					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133765	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133765&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678152	242079898							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266793	CC(=O)CNCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrFN5O3/c1-3-22(32)29-20-10-16-19(11-21(20)33-8-4-7-26-12-14(2)31)27-13-28-23(16)30-18-6-5-15(24)9-17(18)25/h3,5-6,9-11,13,26H,1,4,7-8,12H2,2H3,(H,29,32)(H,27,28,30)	JCZWCPLKQPNPTP-UHFFFAOYSA-N	133766	US8846699, 84	Epidermal growth factor receptor	Homo sapiens		 26					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133766&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100684	242079899							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266794	CCCNC(=O)NC(C)COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H26BrFN6O3/c1-4-8-27-24(34)30-14(3)12-35-21-11-19-16(10-20(21)31-22(33)5-2)23(29-13-28-19)32-18-7-6-15(25)9-17(18)26/h5-7,9-11,13-14H,2,4,8,12H2,1,3H3,(H,31,33)(H2,27,30,34)(H,28,29,32)	WKGRZWRDIRBFPN-UHFFFAOYSA-N	133767	US8846699, 85	Epidermal growth factor receptor	Homo sapiens		 29					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133767	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133767&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678241	242079900							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266795	CCC(COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)NC(C)=O	InChI=1S/C23H23BrFN5O3/c1-4-15(28-13(3)31)11-33-21-10-19-16(9-20(21)29-22(32)5-2)23(27-12-26-19)30-18-7-6-14(24)8-17(18)25/h5-10,12,15H,2,4,11H2,1,3H3,(H,28,31)(H,29,32)(H,26,27,30)	GTDDUMDJAUSXRI-UHFFFAOYSA-N	133768	US8846699, 86	Epidermal growth factor receptor	Homo sapiens		 69					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133768	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133768&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678242	242079901							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266796	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCCNCCC=O)c(NC(=O)C=C)cc12	InChI=1S/C23H23BrFN5O3/c1-2-22(32)29-20-12-16-19(13-21(20)33-10-4-8-26-7-3-9-31)27-14-28-23(16)30-18-6-5-15(24)11-17(18)25/h2,5-6,9,11-14,26H,1,3-4,7-8,10H2,(H,29,32)(H,27,28,30)	YEDYIUXXVIDJPB-UHFFFAOYSA-N	133769	US8846699, 87	Epidermal growth factor receptor	Homo sapiens		 40					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133769	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133769&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87694463	242079902					C00609		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266797	CC(=O)N1CCC(C1)Oc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H21BrFN5O3/c1-3-22(32)28-20-9-16-19(10-21(20)33-15-6-7-30(11-15)13(2)31)26-12-27-23(16)29-18-5-4-14(24)8-17(18)25/h3-5,8-10,12,15H,1,6-7,11H2,2H3,(H,28,32)(H,26,27,29)	ZUDNAVLBOYSKME-UHFFFAOYSA-N	133770	US8846699, 88	Epidermal growth factor receptor	Homo sapiens		 94					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133770&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678244	242079903							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266798	CC(=O)N1CCCC(C1)Oc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H23BrFN5O3/c1-3-23(33)29-21-10-17-20(11-22(21)34-16-5-4-8-31(12-16)14(2)32)27-13-28-24(17)30-19-7-6-15(25)9-18(19)26/h3,6-7,9-11,13,16H,1,4-5,8,12H2,2H3,(H,29,33)(H,27,28,30)	NQECTGFZOQWBSF-UHFFFAOYSA-N	133771	US8846699, 89	Epidermal growth factor receptor	Homo sapiens		 128					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133771	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133771&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678245	242079904							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266799	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNc3nccs3)c(NC(=O)C=C)cc12	InChI=1S/C22H18BrFN6O2S/c1-2-20(31)29-18-10-14-17(11-19(18)32-7-5-25-22-26-6-8-33-22)27-12-28-21(14)30-16-4-3-13(23)9-15(16)24/h2-4,6,8-12H,1,5,7H2,(H,25,26)(H,29,31)(H,27,28,30)	DPSBYADGWLEODU-UHFFFAOYSA-N	133772	US8846699, 90	Epidermal growth factor receptor	Homo sapiens		 295					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133772&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678342	242079905							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266800	Fc1cc(Br)ccc1Nc1ncnc2cc(OCC3CNC(=O)O3)c(NC(=O)C=C)cc12	InChI=1S/C21H17BrFN5O4/c1-2-19(29)27-17-6-13-16(7-18(17)31-9-12-8-24-21(30)32-12)25-10-26-20(13)28-15-4-3-11(22)5-14(15)23/h2-7,10,12H,1,8-9H2,(H,24,30)(H,27,29)(H,25,26,28)	PJTNXYFSQNXMMA-UHFFFAOYSA-N	133773	US8846699, 91	Epidermal growth factor receptor	Homo sapiens		 17					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678343	242079906							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266801	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)c3cccs3)c(NC(=O)C=C)cc12	InChI=1S/C24H19BrFN5O3S/c1-2-22(32)30-19-11-15-18(12-20(19)34-8-7-27-24(33)21-4-3-9-35-21)28-13-29-23(15)31-17-6-5-14(25)10-16(17)26/h2-6,9-13H,1,7-8H2,(H,27,33)(H,30,32)(H,28,29,31)	KARDRLFZPWJXEI-UHFFFAOYSA-N	133774	US8846699, 92	Epidermal growth factor receptor	Homo sapiens		 47					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133774&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678344	242079907							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266802	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)N3CCOCC3)c(NC(=O)C=C)cc12	InChI=1S/C24H24BrFN6O4/c1-2-22(33)30-20-12-16-19(28-14-29-23(16)31-18-4-3-15(25)11-17(18)26)13-21(20)36-8-5-27-24(34)32-6-9-35-10-7-32/h2-4,11-14H,1,5-10H2,(H,27,34)(H,30,33)(H,28,29,31)	MASSBJVLAZTBSY-UHFFFAOYSA-N	133775	US8846699, 93	Epidermal growth factor receptor	Homo sapiens		 36					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133775	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133775&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678345	242079908							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266803	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)N3CCNCC3)c(NC(=O)C=C)cc12	InChI=1S/C24H25BrFN7O3/c1-2-22(34)31-20-12-16-19(29-14-30-23(16)32-18-4-3-15(25)11-17(18)26)13-21(20)36-10-7-28-24(35)33-8-5-27-6-9-33/h2-4,11-14,27H,1,5-10H2,(H,28,35)(H,31,34)(H,29,30,32)	AHAJHWAHRBXVFH-UHFFFAOYSA-N	133776	US8846699, 94	Epidermal growth factor receptor	Homo sapiens		 698					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133776	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133776&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678346	242079909							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266804	CC(=O)N1CCN(CC1)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C26H27BrFN7O4/c1-3-24(37)32-22-13-18-21(30-15-31-25(18)33-20-5-4-17(27)12-19(20)28)14-23(22)39-11-6-29-26(38)35-9-7-34(8-10-35)16(2)36/h3-5,12-15H,1,6-11H2,2H3,(H,29,38)(H,32,37)(H,30,31,33)	XMXFPUFSKWPYBL-UHFFFAOYSA-N	133777	US8846699, 95	Epidermal growth factor receptor	Homo sapiens		 76					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133777&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678347	242079910							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266805	CN1CCN(CC1)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H27BrFN7O3/c1-3-23(35)31-21-13-17-20(29-15-30-24(17)32-19-5-4-16(26)12-18(19)27)14-22(21)37-11-6-28-25(36)34-9-7-33(2)8-10-34/h3-5,12-15H,1,6-11H2,2H3,(H,28,36)(H,31,35)(H,29,30,32)	SPELKVATJBMWHZ-UHFFFAOYSA-N	133778	US8846699, 96	Epidermal growth factor receptor	Homo sapiens		 13					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133778	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133778&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678439	242079911							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266806	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)C3CCCN3)c(NC(=O)C=C)cc12	InChI=1S/C24H24BrFN6O3/c1-2-22(33)31-20-11-15-19(12-21(20)35-9-8-28-24(34)18-4-3-7-27-18)29-13-30-23(15)32-17-6-5-14(25)10-16(17)26/h2,5-6,10-13,18,27H,1,3-4,7-9H2,(H,28,34)(H,31,33)(H,29,30,32)	HFETUOIHWSJPSY-UHFFFAOYSA-N	133779	US8846699, 97	Epidermal growth factor receptor	Homo sapiens		 1954					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133779	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678440	242079912							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266807	CN1CCCC1C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H26BrFN6O3/c1-3-23(34)31-20-12-16-19(29-14-30-24(16)32-18-7-6-15(26)11-17(18)27)13-22(20)36-10-8-28-25(35)21-5-4-9-33(21)2/h3,6-7,11-14,21H,1,4-5,8-10H2,2H3,(H,28,35)(H,31,34)(H,29,30,32)	QKEQHMZWPIXXEY-UHFFFAOYSA-N	133780	US8846699, 100::US8846699, 98	Epidermal growth factor receptor	Homo sapiens		 69					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133780&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678441	242079913							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266808	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)c3ccc[nH]3)c(NC(=O)C=C)cc12	InChI=1S/C24H20BrFN6O3/c1-2-22(33)31-20-11-15-19(12-21(20)35-9-8-28-24(34)18-4-3-7-27-18)29-13-30-23(15)32-17-6-5-14(25)10-16(17)26/h2-7,10-13,27H,1,8-9H2,(H,28,34)(H,31,33)(H,29,30,32)	GAONTQMLYXNEGT-UHFFFAOYSA-N	133781	US8846699, 99	Epidermal growth factor receptor	Homo sapiens		 368					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133781	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133781&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678442	242079914							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266809	CN1CCCC1C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H26BrFN6O3/c1-3-23(34)31-20-12-16-19(29-14-30-24(16)32-18-7-6-15(26)11-17(18)27)13-22(20)36-10-8-28-25(35)21-5-4-9-33(21)2/h3,6-7,11-14,21H,1,4-5,8-10H2,2H3,(H,28,35)(H,31,34)(H,29,30,32)	QKEQHMZWPIXXEY-UHFFFAOYSA-N	133780	US8846699, 100::US8846699, 98	Epidermal growth factor receptor	Homo sapiens		 24					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133780&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678441	242079913							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266810	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)CN3CCCCC3)c(NC(=O)C=C)cc12	InChI=1S/C26H28BrFN6O3/c1-2-24(35)32-22-13-18-21(30-16-31-26(18)33-20-7-6-17(27)12-19(20)28)14-23(22)37-11-8-29-25(36)15-34-9-4-3-5-10-34/h2,6-7,12-14,16H,1,3-5,8-11,15H2,(H,29,36)(H,32,35)(H,30,31,33)	RHGWXTYSJLZTBJ-UHFFFAOYSA-N	133783	US8846699, 101	Epidermal growth factor receptor	Homo sapiens		 7					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133783&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678443	242079915							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266811	CN1CCN(CC(=O)NCCOc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C26H29BrFN7O3/c1-3-24(36)32-22-13-18-21(30-16-31-26(18)33-20-5-4-17(27)12-19(20)28)14-23(22)38-11-6-29-25(37)15-35-9-7-34(2)8-10-35/h3-5,12-14,16H,1,6-11,15H2,2H3,(H,29,37)(H,32,36)(H,30,31,33)	BVCQMVAUBMWNAI-UHFFFAOYSA-N	133784	US8846699, 102	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133784&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678444	242079916							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266812	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)CN3CCOCC3)c(NC(=O)C=C)cc12	InChI=1S/C25H26BrFN6O4/c1-2-23(34)31-21-12-17-20(29-15-30-25(17)32-19-4-3-16(26)11-18(19)27)13-22(21)37-8-5-28-24(35)14-33-6-9-36-10-7-33/h2-4,11-13,15H,1,5-10,14H2,(H,28,35)(H,31,34)(H,29,30,32)	DTTIJFZDEJYJJU-UHFFFAOYSA-N	133785	US8846699, 103	Epidermal growth factor receptor	Homo sapiens		 32					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133785&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100801	242079917							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266813	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)CCN3CCCCC3)c(NC(=O)C=C)cc12	InChI=1S/C27H30BrFN6O3/c1-2-25(36)33-23-15-19-22(31-17-32-27(19)34-21-7-6-18(28)14-20(21)29)16-24(23)38-13-9-30-26(37)8-12-35-10-4-3-5-11-35/h2,6-7,14-17H,1,3-5,8-13H2,(H,30,37)(H,33,36)(H,31,32,34)	MSXNFZGSSBGIKB-UHFFFAOYSA-N	133786	US8846699, 104	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133786&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69106405	242079918							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266814	CC(=O)N1CCCC1C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C26H26BrFN6O4/c1-3-24(36)32-21-12-17-20(30-14-31-25(17)33-19-7-6-16(27)11-18(19)28)13-23(21)38-10-8-29-26(37)22-5-4-9-34(22)15(2)35/h3,6-7,11-14,22H,1,4-5,8-10H2,2H3,(H,29,37)(H,32,36)(H,30,31,33)	OFLPGWWOQOMMAK-UHFFFAOYSA-N	133787	US8846699, 105	Epidermal growth factor receptor	Homo sapiens		 25					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133787&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90657048	242079919							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266815	CCC(=O)N1CCCC1C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C27H28BrFN6O4/c1-3-24(36)33-21-13-17-20(31-15-32-26(17)34-19-8-7-16(28)12-18(19)29)14-23(21)39-11-9-30-27(38)22-6-5-10-35(22)25(37)4-2/h3,7-8,12-15,22H,1,4-6,9-11H2,2H3,(H,30,38)(H,33,36)(H,31,32,34)	BZVKQRRVFARJOO-UHFFFAOYSA-N	133788	US8846699, 106	Epidermal growth factor receptor	Homo sapiens		 196					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133788	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133788&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90657049	242079920							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266816	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)CN3CCCC3)c(NC(=O)C=C)cc12	InChI=1S/C25H26BrFN6O3/c1-2-23(34)31-21-12-17-20(29-15-30-25(17)32-19-6-5-16(26)11-18(19)27)13-22(21)36-10-7-28-24(35)14-33-8-3-4-9-33/h2,5-6,11-13,15H,1,3-4,7-10,14H2,(H,28,35)(H,31,34)(H,29,30,32)	OELVTHONNCJUEV-UHFFFAOYSA-N	133789	US8846699, 107	Epidermal growth factor receptor	Homo sapiens		 45					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133789&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101051	242079921							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266817	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)CN3CC=CC3)c(NC(=O)C=C)cc12 |c:26|	InChI=1S/C25H24BrFN6O3/c1-2-23(34)31-21-12-17-20(29-15-30-25(17)32-19-6-5-16(26)11-18(19)27)13-22(21)36-10-7-28-24(35)14-33-8-3-4-9-33/h2-6,11-13,15H,1,7-10,14H2,(H,28,35)(H,31,34)(H,29,30,32)	QWIUMUFIKLQVQM-UHFFFAOYSA-N	133790	US8846699, 108	Epidermal growth factor receptor	Homo sapiens		 32					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133790	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133790&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69309010	242079922							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266818	Fc1cc(Br)ccc1Nc1ncnc2cc(OCC3=NCCO3)c(NC(=O)C=C)cc12 |t:19|	InChI=1S/C21H17BrFN5O3/c1-2-19(29)27-17-8-13-16(9-18(17)31-10-20-24-5-6-30-20)25-11-26-21(13)28-15-4-3-12(22)7-14(15)23/h2-4,7-9,11H,1,5-6,10H2,(H,27,29)(H,25,26,28)	MWSSSMXMJMXNIJ-UHFFFAOYSA-N	133791	US8846699, 109	Epidermal growth factor receptor	Homo sapiens		 125					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133791&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100619	242079923							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266819	Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)CN3CCC3)c(NC(=O)C=C)cc12	InChI=1S/C24H24BrFN6O3/c1-2-22(33)30-20-11-16-19(12-21(20)35-9-6-27-23(34)13-32-7-3-8-32)28-14-29-24(16)31-18-5-4-15(25)10-17(18)26/h2,4-5,10-12,14H,1,3,6-9,13H2,(H,27,34)(H,30,33)(H,28,29,31)	LRZJFGQTXFKLHL-UHFFFAOYSA-N	133792	US8846699, 110	Epidermal growth factor receptor	Homo sapiens		 987					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133792&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69310070	242079924							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266820	CC(=O)NCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C	InChI=1S/C21H19ClFN5O3/c1-3-20(30)28-18-9-14-17(10-19(18)31-7-6-24-12(2)29)25-11-26-21(14)27-13-4-5-16(23)15(22)8-13/h3-5,8-11H,1,6-7H2,2H3,(H,24,29)(H,28,30)(H,25,26,27)	CFOUMODXZDZQSQ-UHFFFAOYSA-N	133793	US8846699, 111	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133793	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133793&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101132	242079925							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266821	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H19ClFN5O3/c1-3-20(30)27-18-9-14-17(10-19(18)31-7-6-24-12(2)29)25-11-26-21(14)28-16-5-4-13(22)8-15(16)23/h3-5,8-11H,1,6-7H2,2H3,(H,24,29)(H,27,30)(H,25,26,28)	DYYFQDXLUYZKPP-UHFFFAOYSA-N	133794	US8846699, 112	Epidermal growth factor receptor	Homo sapiens		 18					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133794&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100796	242079926							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266822	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1NC(=O)C=C	InChI=1S/C21H19Cl2N5O3/c1-3-20(30)27-18-9-14-17(10-19(18)31-7-6-24-12(2)29)25-11-26-21(14)28-16-5-4-13(22)8-15(16)23/h3-5,8-11H,1,6-7H2,2H3,(H,24,29)(H,27,30)(H,25,26,28)	CXPFXSZABUYPDJ-UHFFFAOYSA-N	133795	US8846699, 113	Epidermal growth factor receptor	Homo sapiens		 49					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133795&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101130	242079927							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266823	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3C(F)(F)F)c2cc1NC(=O)C=C	InChI=1S/C22H19BrF3N5O3/c1-3-20(33)30-18-9-14-17(10-19(18)34-7-6-27-12(2)32)28-11-29-21(14)31-16-5-4-13(23)8-15(16)22(24,25)26/h3-5,8-11H,1,6-7H2,2H3,(H,27,32)(H,30,33)(H,28,29,31)	NLQQNMZMFMGGET-UHFFFAOYSA-N	133796	US8846699, 114	Epidermal growth factor receptor	Homo sapiens		 456					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133796&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101554	242079928							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266824	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3Cl)c2cc1NC(=O)C=C	InChI=1S/C21H19BrClN5O3/c1-3-20(30)27-18-9-14-17(10-19(18)31-7-6-24-12(2)29)25-11-26-21(14)28-16-5-4-13(22)8-15(16)23/h3-5,8-11H,1,6-7H2,2H3,(H,24,29)(H,27,30)(H,25,26,28)	YEPJSPZWMLQZDI-UHFFFAOYSA-N	133797	US8846699, 115	Epidermal growth factor receptor	Homo sapiens		 42					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133797	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133797&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100194	242079929							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266825	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H24ClFN6O3/c1-4-21(32)29-19-10-15-18(11-20(19)34-8-7-26-22(33)12-31(2)3)27-13-28-23(15)30-17-6-5-14(24)9-16(17)25/h4-6,9-11,13H,1,7-8,12H2,2-3H3,(H,26,33)(H,29,32)(H,27,28,30)	PDIFYYQHVFGSAI-UHFFFAOYSA-N	133798	US8846699, 116	Epidermal growth factor receptor	Homo sapiens		 419					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133798&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100478	242079930							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266826	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C23H24ClFN6O3/c1-4-20(32)29-18-10-14-17(11-19(18)34-9-8-26-21(33)12-31(2)3)27-13-28-23(14)30-16-7-5-6-15(24)22(16)25/h4-7,10-11,13H,1,8-9,12H2,2-3H3,(H,26,33)(H,29,32)(H,27,28,30)	JCPZKXGIFPYHHJ-UHFFFAOYSA-N	133799	US8846699, 117	Epidermal growth factor receptor	Homo sapiens		 924					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133799&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100943	242079931							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266827	CC(=O)NCCOc1cc2ncnc(Nc3ccc(F)c(F)c3F)c2cc1NC(=O)C=C	InChI=1S/C21H18F3N5O3/c1-3-18(31)28-16-8-12-15(9-17(16)32-7-6-25-11(2)30)26-10-27-21(12)29-14-5-4-13(22)19(23)20(14)24/h3-5,8-10H,1,6-7H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	YHAXBZNUIZZLFJ-UHFFFAOYSA-N	133800	US8846699, 118	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133800&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100501	242079932							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266828	CC(=O)NCCOc1cc2ncnc(Nc3cc(F)c(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H18BrF2N5O3/c1-3-20(31)28-18-6-12-16(9-19(18)32-5-4-25-11(2)30)26-10-27-21(12)29-17-8-14(23)13(22)7-15(17)24/h3,6-10H,1,4-5H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	UGPMTGRGGQYKIB-UHFFFAOYSA-N	133801	US8846699, 119	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133801&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100921	242079933							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266829	CC(=O)NCCOc1cc2ncnc(Nc3c(F)cc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H18BrF2N5O3/c1-3-19(31)28-17-8-13-16(9-18(17)32-5-4-25-11(2)30)26-10-27-21(13)29-20-14(23)6-12(22)7-15(20)24/h3,6-10H,1,4-5H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	PSPLRUCSARYWEJ-UHFFFAOYSA-N	133802	US8846699, 120	Epidermal growth factor receptor	Homo sapiens		 22					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133802&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101149	242079934							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266830	CC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H18Cl2FN5O3/c1-3-20(31)28-18-6-12-16(9-19(18)32-5-4-25-11(2)30)26-10-27-21(12)29-17-8-14(23)13(22)7-15(17)24/h3,6-10H,1,4-5H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	TZDAEWGVZVGBPE-UHFFFAOYSA-N	133803	US8846699, 121	Epidermal growth factor receptor	Homo sapiens		 5					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133803&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100914	242079935							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266831	CC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3Cl)c2cc1NC(=O)C=C	InChI=1S/C21H18Cl3N5O3/c1-3-20(31)28-18-6-12-16(9-19(18)32-5-4-25-11(2)30)26-10-27-21(12)29-17-8-14(23)13(22)7-15(17)24/h3,6-10H,1,4-5H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	GANZOBRZAGYPGJ-UHFFFAOYSA-N	133804	US8846699, 122	Epidermal growth factor receptor	Homo sapiens		 876					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133804&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101477	242079936							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266832	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3c(F)cc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrF2N6O3/c1-4-20(33)30-18-9-14-17(10-19(18)35-6-5-27-21(34)11-32(2)3)28-12-29-23(14)31-22-15(25)7-13(24)8-16(22)26/h4,7-10,12H,1,5-6,11H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	FYZZYOSCIAZCBA-UHFFFAOYSA-N	133805	US8846699, 123	Epidermal growth factor receptor	Homo sapiens		 175					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133805&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100740	242079937							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266833	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(F)c3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrF2N6O3/c1-4-19(33)30-17-9-13-16(10-18(17)35-8-7-27-20(34)11-32(2)3)28-12-29-23(13)31-15-6-5-14(24)21(25)22(15)26/h4-6,9-10,12H,1,7-8,11H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	ARBSTGKTOSHPOE-UHFFFAOYSA-N	133806	US8846699, 124	Epidermal growth factor receptor	Homo sapiens		 18					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133806&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101343	242079938							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266834	CCN(CC)CCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(F)c3F)c2cc1NC(=O)C=C	InChI=1S/C26H29BrF2N6O3/c1-4-22(36)33-20-13-16-19(14-21(20)38-12-10-30-23(37)9-11-35(5-2)6-3)31-15-32-26(16)34-18-8-7-17(27)24(28)25(18)29/h4,7-8,13-15H,1,5-6,9-12H2,2-3H3,(H,30,37)(H,33,36)(H,31,32,34)	YRLMDFYRQYWKJM-UHFFFAOYSA-N	133807	US8846699, 125	Epidermal growth factor receptor	Homo sapiens		 19					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133807&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100658	242079939							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266835	Fc1c(Br)ccc(Nc2ncnc3cc(OCCNC(=O)CCN4CCCCC4)c(NC(=O)C=C)cc23)c1F	InChI=1S/C27H29BrF2N6O3/c1-2-23(37)34-21-14-17-20(32-16-33-27(17)35-19-7-6-18(28)25(29)26(19)30)15-22(21)39-13-9-31-24(38)8-12-36-10-4-3-5-11-36/h2,6-7,14-16H,1,3-5,8-13H2,(H,31,38)(H,34,37)(H,32,33,35)	KXWGCUQJTHVLTN-UHFFFAOYSA-N	133808	US8846699, 126	Epidermal growth factor receptor	Homo sapiens		 894					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133808&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100402	242079940							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266836	CN(C)CCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(F)c3F)c2cc1NC(=O)C=C	InChI=1S/C25H27BrF2N6O3/c1-4-21(35)32-19-12-15-18(13-20(19)37-11-9-29-22(36)6-5-10-34(2)3)30-14-31-25(15)33-17-8-7-16(26)23(27)24(17)28/h4,7-8,12-14H,1,5-6,9-11H2,2-3H3,(H,29,36)(H,32,35)(H,30,31,33)	ZSDKABQQQPOUIS-UHFFFAOYSA-N	133809	US8846699, 127	Epidermal growth factor receptor	Homo sapiens		 568					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133809&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100879	242079941							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266837	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Cl)nc3)c2cc1NC(=O)C=C	InChI=1S/C20H19ClN6O3/c1-3-19(29)27-16-8-14-15(9-17(16)30-7-6-22-12(2)28)24-11-25-20(14)26-13-4-5-18(21)23-10-13/h3-5,8-11H,1,6-7H2,2H3,(H,22,28)(H,27,29)(H,24,25,26)	LZAXPBKXHBEHAS-UHFFFAOYSA-N	133810	US8846699, 128	Epidermal growth factor receptor	Homo sapiens		 65					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87694328	242079942							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266838	COc1cc(Nc2ncnc3cc(OCCNC(C)=O)c(NC(=O)C=C)cc23)c(F)cc1Cl	InChI=1S/C22H21ClFN5O4/c1-4-21(31)28-18-7-13-16(9-20(18)33-6-5-25-12(2)30)26-11-27-22(13)29-17-10-19(32-3)14(23)8-15(17)24/h4,7-11H,1,5-6H2,2-3H3,(H,25,30)(H,28,31)(H,26,27,29)	VAYPWRLVYXYEQY-UHFFFAOYSA-N	133811	US8846699, 129	Epidermal growth factor receptor	Homo sapiens		 80					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133811&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100292	242079943							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266839	CC(=O)NCCOc1cc2ncnc(Nc3ccc(OCc4cccnc4)c(Cl)c3)c2cc1NC(=O)C=C	InChI=1S/C27H25ClN6O4/c1-3-26(36)34-23-12-20-22(13-25(23)37-10-9-30-17(2)35)31-16-32-27(20)33-19-6-7-24(21(28)11-19)38-15-18-5-4-8-29-14-18/h3-8,11-14,16H,1,9-10,15H2,2H3,(H,30,35)(H,34,36)(H,31,32,33)	KLGKOFYRMVUFIH-UHFFFAOYSA-N	133812	US8846699, 130	Epidermal growth factor receptor	Homo sapiens		 796					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133812&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100043	242079944							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266840	CONC(=O)c1cc(Nc2ncnc3cc(OCCNC(C)=O)c(NC(=O)C=C)cc23)c(F)cc1Br	InChI=1S/C23H22BrFN6O5/c1-4-21(33)29-19-8-14-17(10-20(19)36-6-5-26-12(2)32)27-11-28-22(14)30-18-7-13(23(34)31-35-3)15(24)9-16(18)25/h4,7-11H,1,5-6H2,2-3H3,(H,26,32)(H,29,33)(H,31,34)(H,27,28,30)	JVCLZAIVGDIVLO-UHFFFAOYSA-N	133813	US8846699, 131	Epidermal growth factor receptor	Homo sapiens		 10000					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133813&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87694338	242079945							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266841	COc1cc(Nc2ncnc3cc(OCCNC(C)=O)c(NC(=O)C=C)cc23)c(Cl)cc1Cl	InChI=1S/C22H21Cl2N5O4/c1-4-21(31)28-18-7-13-16(9-20(18)33-6-5-25-12(2)30)26-11-27-22(13)29-17-10-19(32-3)15(24)8-14(17)23/h4,7-11H,1,5-6H2,2-3H3,(H,25,30)(H,28,31)(H,26,27,29)	KEOKRCKVDHLVOO-UHFFFAOYSA-N	133814	US8846699, 132	Epidermal growth factor receptor	Homo sapiens		 42					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133814&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101236	242079946							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266842	CC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H18BrClFN5O3/c1-3-20(31)28-18-6-12-16(9-19(18)32-5-4-25-11(2)30)26-10-27-21(12)29-17-8-14(23)13(22)7-15(17)24/h3,6-10H,1,4-5H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	HCNASUOYSCKZNG-UHFFFAOYSA-N	133815	US8846699, 133	Epidermal growth factor receptor	Homo sapiens		 15					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133815&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101128	242079947							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266843	CC(=O)CNCCOc1cc2ncnc(Nc3cc(Cl)c(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H20BrClFN5O3/c1-3-21(32)29-19-6-13-17(9-20(19)33-5-4-26-10-12(2)31)27-11-28-22(13)30-18-8-15(24)14(23)7-16(18)25/h3,6-9,11,26H,1,4-5,10H2,2H3,(H,29,32)(H,27,28,30)	MLSWVVZNGKLNPB-UHFFFAOYSA-N	133816	US8846699, 134	Epidermal growth factor receptor	Homo sapiens		 13					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133816&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100437	242079948							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266844	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrClFN6O3/c1-4-21(33)30-19-7-13-17(10-20(19)35-6-5-27-22(34)11-32(2)3)28-12-29-23(13)31-18-9-15(25)14(24)8-16(18)26/h4,7-10,12H,1,5-6,11H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	PNENUMJQDWNJEW-UHFFFAOYSA-N	133817	US8846699, 135	Epidermal growth factor receptor	Homo sapiens		 9					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133817&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100367	242079949							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266845	CN(C)CCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C21H20Cl2FN5O2/c1-4-20(30)27-18-7-12-16(10-19(18)31-6-5-29(2)3)25-11-26-21(12)28-17-9-14(23)13(22)8-15(17)24/h4,7-11H,1,5-6H2,2-3H3,(H,27,30)(H,25,26,28)	ZMTLVNLUQRLETC-UHFFFAOYSA-N	133818	US8846699, 136	Epidermal growth factor receptor	Homo sapiens		 321					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133818&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101380	242079950							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266846	CC(=O)CNCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H20Cl2FN5O3/c1-3-21(32)29-19-6-13-17(9-20(19)33-5-4-26-10-12(2)31)27-11-28-22(13)30-18-8-15(24)14(23)7-16(18)25/h3,6-9,11,26H,1,4-5,10H2,2H3,(H,29,32)(H,27,28,30)	LAPPKGYTRPDHPM-UHFFFAOYSA-N	133819	US8846699, 137	Epidermal growth factor receptor	Homo sapiens		 4					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133819&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100539	242079951							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266847	COCC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H20Cl2FN5O4/c1-3-20(31)29-18-6-12-16(9-19(18)34-5-4-26-21(32)10-33-2)27-11-28-22(12)30-17-8-14(24)13(23)7-15(17)25/h3,6-9,11H,1,4-5,10H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	YSZALBLOXLXRCK-UHFFFAOYSA-N	133820	US8846699, 138	Epidermal growth factor receptor	Homo sapiens		 20					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133820&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100990	242079952							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266848	CS(=O)(=O)CC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H20Cl2FN5O5S/c1-3-20(31)29-18-6-12-16(9-19(18)35-5-4-26-21(32)10-36(2,33)34)27-11-28-22(12)30-17-8-14(24)13(23)7-15(17)25/h3,6-9,11H,1,4-5,10H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	XQNPQCDWAUIUPF-UHFFFAOYSA-N	133821	US8846699, 139	Epidermal growth factor receptor	Homo sapiens		 40					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133821&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100433	242079953							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266849	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1NC(=O)C=C	InChI=1S/C23H23Cl2FN6O3/c1-4-21(33)30-19-7-13-17(10-20(19)35-6-5-27-22(34)11-32(2)3)28-12-29-23(13)31-18-9-15(25)14(24)8-16(18)26/h4,7-10,12H,1,5-6,11H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	SHRZDXFZUPQARN-UHFFFAOYSA-N	133822	US8846699, 140	Epidermal growth factor receptor	Homo sapiens		 9					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133822&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100476	242079954							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266850	CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C21H18BrClFN5O3/c1-3-18(31)28-16-8-12-15(9-17(16)32-7-6-25-11(2)30)26-10-27-21(12)29-14-5-4-13(22)19(23)20(14)24/h3-5,8-10H,1,6-7H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	GENOBEOZZLHYRL-UHFFFAOYSA-N	133823	US8846699, 141	Epidermal growth factor receptor	Homo sapiens		 13					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133823&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100738	242079955							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266851	CC(=O)CNCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C22H20BrClFN5O3/c1-3-19(32)29-17-8-13-16(9-18(17)33-7-6-26-10-12(2)31)27-11-28-22(13)30-15-5-4-14(23)20(24)21(15)25/h3-5,8-9,11,26H,1,6-7,10H2,2H3,(H,29,32)(H,27,28,30)	OHXVMYFKIJOOLR-UHFFFAOYSA-N	133824	US8846699, 142	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133824&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101066	242079956							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266852	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrClFN6O3/c1-4-19(33)30-17-9-13-16(10-18(17)35-8-7-27-20(34)11-32(2)3)28-12-29-23(13)31-15-6-5-14(24)21(25)22(15)26/h4-6,9-10,12H,1,7-8,11H2,2-3H3,(H,27,34)(H,30,33)(H,28,29,31)	FQIQGTLQUPPSRD-UHFFFAOYSA-N	133825	US8846699, 143	Epidermal growth factor receptor	Homo sapiens		 19					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133825&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100198	242079957							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266853	CCN(CC)CCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C26H29BrClFN6O3/c1-4-22(36)33-20-13-16-19(14-21(20)38-12-10-30-23(37)9-11-35(5-2)6-3)31-15-32-26(16)34-18-8-7-17(27)24(28)25(18)29/h4,7-8,13-15H,1,5-6,9-12H2,2-3H3,(H,30,37)(H,33,36)(H,31,32,34)	QASOHECZVDQOIK-UHFFFAOYSA-N	133826	US8846699, 144	Epidermal growth factor receptor	Homo sapiens		 7					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133826&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100537	242079958							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266854	OCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C22H20BrClFN5O4/c1-2-18(32)29-16-9-12-15(10-17(16)34-8-6-26-19(33)5-7-31)27-11-28-22(12)30-14-4-3-13(23)20(24)21(14)25/h2-4,9-11,31H,1,5-8H2,(H,26,33)(H,29,32)(H,27,28,30)	VXXSTZLCZOCSDY-UHFFFAOYSA-N	133827	US8846699, 145	Epidermal growth factor receptor	Homo sapiens		 41					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133827&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100637	242079959							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266855	COCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C22H20BrClFN5O4/c1-3-18(31)29-16-8-12-15(9-17(16)34-7-6-26-19(32)10-33-2)27-11-28-22(12)30-14-5-4-13(23)20(24)21(14)25/h3-5,8-9,11H,1,6-7,10H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	URGDWDVOUMUUID-UHFFFAOYSA-N	133828	US8846699, 146	Epidermal growth factor receptor	Homo sapiens		 213					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133828&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101036	242079960							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266856	Fc1c(Cl)c(Br)ccc1Nc1ncnc2cc(OCCNC(=O)CCN3CCCCC3)c(NC(=O)C=C)cc12	InChI=1S/C27H29BrClFN6O3/c1-2-23(37)34-21-14-17-20(32-16-33-27(17)35-19-7-6-18(28)25(29)26(19)30)15-22(21)39-13-9-31-24(38)8-12-36-10-4-3-5-11-36/h2,6-7,14-16H,1,3-5,8-13H2,(H,31,38)(H,34,37)(H,32,33,35)	JLRRXORWMUQGQX-UHFFFAOYSA-N	133829	US8846699, 147	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133829&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100375	242079961							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266857	CN(C)CCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C25H27BrClFN6O3/c1-4-21(35)32-19-12-15-18(13-20(19)37-11-9-29-22(36)6-5-10-34(2)3)30-14-31-25(15)33-17-8-7-16(26)23(27)24(17)28/h4,7-8,12-14H,1,5-6,9-11H2,2-3H3,(H,29,36)(H,32,35)(H,30,31,33)	UDBLADDGFQBCCT-UHFFFAOYSA-N	133830	US8846699, 148	Epidermal growth factor receptor	Homo sapiens		 28					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133830&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100751	242079962							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266858	OCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C21H18BrClFN5O4/c1-2-17(31)28-15-7-11-14(8-16(15)33-6-5-25-18(32)9-30)26-10-27-21(11)29-13-4-3-12(22)19(23)20(13)24/h2-4,7-8,10,30H,1,5-6,9H2,(H,25,32)(H,28,31)(H,26,27,29)	AYRINFKNJPHSKZ-UHFFFAOYSA-N	133831	US8846699, 149	Epidermal growth factor receptor	Homo sapiens		 16					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133831&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101018	242079963							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266859	COCCC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C23H22BrClFN5O4/c1-3-19(32)30-17-10-13-16(11-18(17)35-9-7-27-20(33)6-8-34-2)28-12-29-23(13)31-15-5-4-14(24)21(25)22(15)26/h3-5,10-12H,1,6-9H2,2H3,(H,27,33)(H,30,32)(H,28,29,31)	HUFVZUNTJJLXLG-UHFFFAOYSA-N	133832	US8846699, 150	Epidermal growth factor receptor	Homo sapiens		 21					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133832&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100420	242079964							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266860	CCN(CC)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C25H27BrClFN6O3/c1-4-21(35)32-19-11-15-18(12-20(19)37-10-9-29-22(36)13-34(5-2)6-3)30-14-31-25(15)33-17-8-7-16(26)23(27)24(17)28/h4,7-8,11-12,14H,1,5-6,9-10,13H2,2-3H3,(H,29,36)(H,32,35)(H,30,31,33)	ZBOCBASKJOBZTN-UHFFFAOYSA-N	133833	US8846699, 151	Epidermal growth factor receptor	Homo sapiens		 58					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133833&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100750	242079965							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266861	CN(C)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1NC(=O)C=C	InChI=1S/C23H24BrClN6O3/c1-4-21(32)30-19-10-15-18(11-20(19)34-8-7-26-22(33)12-31(2)3)27-13-28-23(15)29-14-5-6-16(24)17(25)9-14/h4-6,9-11,13H,1,7-8,12H2,2-3H3,(H,26,33)(H,30,32)(H,27,28,29)	HRMPHPPMLURQFC-UHFFFAOYSA-N	133834	US8846699, 152	Epidermal growth factor receptor	Homo sapiens		 75					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133834&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100334	242079966							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266862	CN(C)CC(=O)NC(C)(C)COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H28BrFN6O3/c1-6-22(34)30-20-10-16-19(11-21(20)36-13-25(2,3)32-23(35)12-33(4)5)28-14-29-24(16)31-18-8-7-15(26)9-17(18)27/h6-11,14H,1,12-13H2,2-5H3,(H,30,34)(H,32,35)(H,28,29,31)	DDJVPPJAZUNTIE-UHFFFAOYSA-N	133835	US8846699, 154	Epidermal growth factor receptor	Homo sapiens		 222					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133835&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100860	242079967							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266863	CCN(CC)CCC(=O)NC(C)COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C27H32BrFN6O3/c1-5-25(36)33-23-13-19-22(30-16-31-27(19)34-21-9-8-18(28)12-20(21)29)14-24(23)38-15-17(4)32-26(37)10-11-35(6-2)7-3/h5,8-9,12-14,16-17H,1,6-7,10-11,15H2,2-4H3,(H,32,37)(H,33,36)(H,30,31,34)	XKROSFHVZFKVQN-UHFFFAOYSA-N	133836	US8846699, 155	Epidermal growth factor receptor	Homo sapiens		 24					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133836&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100283	242079968							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266864	CC(COc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C24H25BrClFN6O3/c1-5-20(34)31-18-8-14-17(9-19(18)36-11-13(2)30-21(35)10-33(3)4)28-12-29-24(14)32-16-7-6-15(25)22(26)23(16)27/h5-9,12-13H,1,10-11H2,2-4H3,(H,30,35)(H,31,34)(H,28,29,32)	GRBIBILPWGFKCS-UHFFFAOYSA-N	133837	US8846699, 157	Epidermal growth factor receptor	Homo sapiens		 88					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133837&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100385	242079969							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266865	C[C@@H](COc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C24H25BrClFN6O3/c1-5-20(34)31-18-8-14-17(9-19(18)36-11-13(2)30-21(35)10-33(3)4)28-12-29-24(14)32-16-7-6-15(25)22(26)23(16)27/h5-9,12-13H,1,10-11H2,2-4H3,(H,30,35)(H,31,34)(H,28,29,32)	GRBIBILPWGFKCS-UHFFFAOYSA-N	133838	US8846699, 163::US8846699, 158	Epidermal growth factor receptor	Homo sapiens		 23.1					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133838&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100384	242079970							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266866	C[C@H](COc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C24H25BrClFN6O3/c1-5-20(34)31-18-8-14-17(9-19(18)36-11-13(2)30-21(35)10-33(3)4)28-12-29-24(14)32-16-7-6-15(25)22(26)23(16)27/h5-9,12-13H,1,10-11H2,2-4H3,(H,30,35)(H,31,34)(H,28,29,32)	GRBIBILPWGFKCS-UHFFFAOYSA-N	133839	US8846699, 164::US8846699, 159	Epidermal growth factor receptor	Homo sapiens		 286					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133839&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101073	242079971							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266867	CCC(COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C25H28BrFN6O3/c1-5-16(30-24(35)12-33(3)4)13-36-22-11-20-17(10-21(22)31-23(34)6-2)25(29-14-28-20)32-19-8-7-15(26)9-18(19)27/h6-11,14,16H,2,5,12-13H2,1,3-4H3,(H,30,35)(H,31,34)(H,28,29,32)	OIPVBSQFFJQZSU-UHFFFAOYSA-N	133840	US8846699, 160	Epidermal growth factor receptor	Homo sapiens		 23					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133840&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100952	242079972							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266868	COCC(N(C)C)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H28BrFN6O4/c1-5-23(34)31-20-11-16-19(29-14-30-24(16)32-18-7-6-15(26)10-17(18)27)12-22(20)37-9-8-28-25(35)21(13-36-4)33(2)3/h5-7,10-12,14,21H,1,8-9,13H2,2-4H3,(H,28,35)(H,31,34)(H,29,30,32)	XOJPXZWMZWFJFS-UHFFFAOYSA-N	133841	US8846699, 161	Epidermal growth factor receptor	Homo sapiens		 57					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133841&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100692	242079973							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266869	CN(C)C(CO)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C24H26BrFN6O4/c1-4-22(34)30-19-10-15-18(11-21(19)36-8-7-27-24(35)20(12-33)32(2)3)28-13-29-23(15)31-17-6-5-14(25)9-16(17)26/h4-6,9-11,13,20,33H,1,7-8,12H2,2-3H3,(H,27,35)(H,30,34)(H,28,29,31)	GNZCXFIXXQWSSZ-UHFFFAOYSA-N	133842	US8846699, 162	Epidermal growth factor receptor	Homo sapiens		 126					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133842&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100837	242079974							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266870	C[C@@H](COc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C24H25BrClFN6O3/c1-5-20(34)31-18-8-14-17(9-19(18)36-11-13(2)30-21(35)10-33(3)4)28-12-29-24(14)32-16-7-6-15(25)22(26)23(16)27/h5-9,12-13H,1,10-11H2,2-4H3,(H,30,35)(H,31,34)(H,28,29,32)	GRBIBILPWGFKCS-UHFFFAOYSA-N	133838	US8846699, 163::US8846699, 158	Epidermal growth factor receptor	Homo sapiens		 12					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133838&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100384	242079970							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266871	C[C@H](COc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C	InChI=1S/C24H25BrClFN6O3/c1-5-20(34)31-18-8-14-17(9-19(18)36-11-13(2)30-21(35)10-33(3)4)28-12-29-24(14)32-16-7-6-15(25)22(26)23(16)27/h5-9,12-13H,1,10-11H2,2-4H3,(H,30,35)(H,31,34)(H,28,29,32)	GRBIBILPWGFKCS-UHFFFAOYSA-N	133839	US8846699, 164::US8846699, 159	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133839&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101073	242079971							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266872	COC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C21H18BrClFN5O4/c1-3-17(30)28-15-8-11-14(9-16(15)33-7-6-25-21(31)32-2)26-10-27-20(11)29-13-5-4-12(22)18(23)19(13)24/h3-5,8-10H,1,6-7H2,2H3,(H,25,31)(H,28,30)(H,26,27,29)	QQNYFZMXLDOHEF-UHFFFAOYSA-N	133845	US8846699, 165	Epidermal growth factor receptor	Homo sapiens		 98					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133845&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90657050	242079975							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266873	COc1cc(Nc2ncnc3cc(OCCNC(=O)CN(C)C)c(NC(=O)C=C)cc23)c(OC)cc1Cl	InChI=1S/C25H29ClN6O5/c1-6-23(33)30-18-9-15-17(11-22(18)37-8-7-27-24(34)13-32(2)3)28-14-29-25(15)31-19-12-20(35-4)16(26)10-21(19)36-5/h6,9-12,14H,1,7-8,13H2,2-5H3,(H,27,34)(H,30,33)(H,28,29,31)	QCROOTBGMAHVGX-UHFFFAOYSA-N	133846	US8846699, 166	Epidermal growth factor receptor	Homo sapiens		 14					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133846	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133846&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100135	242079976							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266874	CCN(CC)CC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C25H28BrFN6O3/c1-4-23(34)31-21-12-17-20(13-22(21)36-10-9-28-24(35)14-33(5-2)6-3)29-15-30-25(17)32-19-8-7-16(26)11-18(19)27/h4,7-8,11-13,15H,1,5-6,9-10,14H2,2-3H3,(H,28,35)(H,31,34)(H,29,30,32)	LYDMZKUPEIUXHG-UHFFFAOYSA-N	133847	US8846699, 167	Epidermal growth factor receptor	Homo sapiens		 26					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133847	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133847&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101165	242079977							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266875	CCNC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrClFN6O3/c1-3-18(32)30-16-9-12-15(10-17(16)34-8-7-27-22(33)26-4-2)28-11-29-21(12)31-14-6-5-13(23)19(24)20(14)25/h3,5-6,9-11H,1,4,7-8H2,2H3,(H,30,32)(H2,26,27,33)(H,28,29,31)	KOVLLCNIJRZXSU-UHFFFAOYSA-N	133848	US8846699, 168	Epidermal growth factor receptor	Homo sapiens		 8					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133848&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101056	242079978							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266876	CCCNC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C23H23BrClFN6O3/c1-3-7-27-23(34)28-8-9-35-18-11-16-13(10-17(18)31-19(33)4-2)22(30-12-29-16)32-15-6-5-14(24)20(25)21(15)26/h4-6,10-12H,2-3,7-9H2,1H3,(H,31,33)(H2,27,28,34)(H,29,30,32)	UCGXLPHREMHIFF-UHFFFAOYSA-N	133849	US8846699, 169	Epidermal growth factor receptor	Homo sapiens		 26					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133849&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101069	242079979							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266877	CCNC(=S)NCCOc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C	InChI=1S/C22H21BrClFN6O2S/c1-3-18(32)30-16-9-12-15(10-17(16)33-8-7-27-22(34)26-4-2)28-11-29-21(12)31-14-6-5-13(23)19(24)20(14)25/h3,5-6,9-11H,1,4,7-8H2,2H3,(H,30,32)(H2,26,27,34)(H,28,29,31)	JKFAFNGFEBNHQY-UHFFFAOYSA-N	133850	US8846699, 170	Epidermal growth factor receptor	Homo sapiens		 68					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133850&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87694224	242079980							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266878	CCNC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1	InChI=1S/C26H28BrFN6O3/c1-3-24(35)32-22-12-18-21(30-15-31-25(18)33-20-6-5-17(27)11-19(20)28)13-23(22)37-14-16-7-9-34(10-8-16)26(36)29-4-2/h3,5-6,11-13,15-16H,1,4,7-10,14H2,2H3,(H,29,36)(H,32,35)(H,30,31,33)	QYXDMOYCHRRSMH-UHFFFAOYSA-N	133851	US8846699, 171	Epidermal growth factor receptor	Homo sapiens		 20					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133851&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69100973	242079981							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266879	COc1cc(Nc2ncnc3cc(OCCNC(C)=O)c(NC(=O)C=C)cc23)c(OC)cc1Cl	InChI=1S/C23H24ClN5O5/c1-5-22(31)28-17-8-14-16(10-21(17)34-7-6-25-13(2)30)26-12-27-23(14)29-18-11-19(32-3)15(24)9-20(18)33-4/h5,8-12H,1,6-7H2,2-4H3,(H,25,30)(H,28,31)(H,26,27,29)	UVUWLFQIXSVZBI-UHFFFAOYSA-N	133852	US8846699, 172	Epidermal growth factor receptor	Homo sapiens		 87					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133852&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69101050	242079982							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
266880	CC(N)C(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C	InChI=1S/C22H22BrFN6O3/c1-3-20(31)29-18-9-14-17(10-19(18)33-7-6-26-22(32)12(2)25)27-11-28-21(14)30-16-5-4-13(23)8-15(16)24/h3-5,8-12H,1,6-7,25H2,2H3,(H,26,32)(H,29,31)(H,27,28,30)	PPYSXGBNOGMWKR-UHFFFAOYSA-N	133853	US8846699, 173	Epidermal growth factor receptor	Homo sapiens		 18					7.4000	25.00 C	US Patent		10.7270/Q2KW5DRK		aid1800686	US8846699	Ahn, Y; Kim, JW; Bang, KC; Park, BW; Kim, SY; Lee, K; Lee, K; Ko, M; Kim, HK; Kim, YH; Kim, MS; Lee, GS	9/30/2014	3/3/2015	Hanmi Pharm.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=133853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=133853&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16678543	242079983							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
274969	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1C |r|	InChI=1S/C32H31ClN6O3/c1-3-41-30-17-27-25(16-28(30)38-31(40)12-10-24-8-6-14-39(24)2)32(21(18-34)19-36-27)37-22-9-11-29(26(33)15-22)42-20-23-7-4-5-13-35-23/h4-5,7,9-13,15-17,19,24H,3,6,8,14,20H2,1-2H3,(H,36,37)(H,38,40)	SADXACCFNXBCFY-UHFFFAOYSA-N	139988	US8901140, 1::US9358227, 1	Epidermal growth factor receptor	Homo sapiens		 48							US Patent		10.7270/Q2VX0F76		aid1800785	US8901140	Tang, PC; Li, X; Wang, B; Wang, J; Chen, L	12/2/2014	5/4/2015	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139988	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139988&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038981	250184292							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
274970	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1 |r|	InChI=1S/C31H29ClN6O3/c1-2-40-29-16-26-24(15-27(29)38-30(39)11-9-21-7-5-13-34-21)31(20(17-33)18-36-26)37-22-8-10-28(25(32)14-22)41-19-23-6-3-4-12-35-23/h3-4,6,8-12,14-16,18,21,34H,2,5,7,13,19H2,1H3,(H,36,37)(H,38,39)	BXYUWIKGVQXGEA-UHFFFAOYSA-N	139989	US8901140, 2::US9358227, 2	Epidermal growth factor receptor	Homo sapiens		 6							US Patent		10.7270/Q2VX0F76		aid1800785	US8901140	Tang, PC; Li, X; Wang, B; Wang, J; Chen, L	12/2/2014	5/4/2015	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139989&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039032	250184293							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
274971	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1C[C@@H](O)CN1C |r|	InChI=1S/C32H31ClN6O4/c1-3-42-30-15-27-25(14-28(30)38-31(41)10-8-23-13-24(40)18-39(23)2)32(20(16-34)17-36-27)37-21-7-9-29(26(33)12-21)43-19-22-6-4-5-11-35-22/h4-12,14-15,17,23-24,40H,3,13,18-19H2,1-2H3,(H,36,37)(H,38,41)	MGJMZWXLGRKRAN-UHFFFAOYSA-N	139990	US8901140, 3::US9358227, 3	Epidermal growth factor receptor	Homo sapiens		 59							US Patent		10.7270/Q2VX0F76		aid1800785	US8901140	Tang, PC; Li, X; Wang, B; Wang, J; Chen, L	12/2/2014	5/4/2015	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139990	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139990&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038275	250184294							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
274972	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C |r|	InChI=1S/C32H31ClN6O3/c1-3-41-30-17-27-25(16-28(30)38-31(40)12-10-24-8-6-14-39(24)2)32(21(18-34)19-36-27)37-22-9-11-29(26(33)15-22)42-20-23-7-4-5-13-35-23/h4-5,7,9-13,15-17,19,24H,3,6,8,14,20H2,1-2H3,(H,36,37)(H,38,40)	SADXACCFNXBCFY-UHFFFAOYSA-N	139991	US8901140, 5::US9358227, 5	Epidermal growth factor receptor	Homo sapiens		 13							US Patent		10.7270/Q2VX0F76		aid1800785	US8901140	Tang, PC; Li, X; Wang, B; Wang, J; Chen, L	12/2/2014	5/4/2015	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139991&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039030	250184295							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
274973	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1C |r|	InChI=1S/C24H25ClFN5O2/c1-3-33-22-13-20-17(12-21(22)30-23(32)9-7-16-5-4-10-31(16)2)24(28-14-27-20)29-15-6-8-19(26)18(25)11-15/h6-9,11-14,16H,3-5,10H2,1-2H3,(H,30,32)(H,27,28,29)	JZQOPZNZLUYLTR-UHFFFAOYSA-N	139992	US8901140, 7::US9358227, 7	Epidermal growth factor receptor	Homo sapiens		 4							US Patent		10.7270/Q2VX0F76		aid1800785	US8901140	Tang, PC; Li, X; Wang, B; Wang, J; Chen, L	12/2/2014	5/4/2015	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139992	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139992&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039031	250184296							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
274974	COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C |r|	InChI=1S/C25H27ClFN5O3/c1-32-9-3-4-17(32)6-8-24(33)31-22-13-18-21(14-23(22)35-11-10-34-2)28-15-29-25(18)30-16-5-7-20(27)19(26)12-16/h5-8,12-15,17H,3-4,9-11H2,1-2H3,(H,31,33)(H,28,29,30)	JLZPLOMYCANQFI-UHFFFAOYSA-N	139993	US8901140, 8::US9358227, 8	Epidermal growth factor receptor	Homo sapiens		 2							US Patent		10.7270/Q2VX0F76		aid1800785	US8901140	Tang, PC; Li, X; Wang, B; Wang, J; Chen, L	12/2/2014	5/4/2015	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139993&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038277	250184297							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
274975	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C |r|	InChI=1S/C24H25ClFN5O2/c1-3-33-22-13-20-17(12-21(22)30-23(32)9-7-16-5-4-10-31(16)2)24(28-14-27-20)29-15-6-8-19(26)18(25)11-15/h6-9,11-14,16H,3-5,10H2,1-2H3,(H,30,32)(H,27,28,29)	JZQOPZNZLUYLTR-UHFFFAOYSA-N	139994	US8901140, 9::US9358227, 9	Epidermal growth factor receptor	Homo sapiens		 2							US Patent		10.7270/Q2VX0F76		aid1800785	US8901140	Tang, PC; Li, X; Wang, B; Wang, J; Chen, L	12/2/2014	5/4/2015	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139994&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039044	250184298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
276192	NS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C28H25ClFN5O4S/c29-24-14-21(5-8-27(24)38-16-18-2-1-3-20(30)12-18)35-28-23-13-19(4-7-25(23)33-17-34-28)26-9-6-22(39-26)15-32-10-11-40(31,36)37/h1-9,12-14,17,32H,10-11,15-16H2,(H2,31,36,37)(H,33,34,35)	ZZKJYWJMKZJTKA-UHFFFAOYSA-N	140984	US8916574, Compound 1	Epidermal growth factor receptor	Homo sapiens		 2.71						25.00 C	US Patent		10.7270/Q2SX6BXK		aid1800803	US8916574	Wang, J; Fan, C; Zhang, L; Guo, Z; Li, Y; Yang, S; Yan, S; Zhu, J; Yang, Q; Zhang, M	12/23/2014	5/11/2015	Qilu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=140984	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=140984&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51348454	250231186							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
276193	CS(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O3S/c1-39(36)12-11-32-16-23-7-10-27(38-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)37-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	OAMVGUFHZPRXOM-UHFFFAOYSA-N	140985	US8916574, Compound 2	Epidermal growth factor receptor	Homo sapiens		 52.67						25.00 C	US Patent		10.7270/Q2SX6BXK		aid1800803	US8916574	Wang, J; Fan, C; Zhang, L; Guo, Z; Li, Y; Yang, S; Yan, S; Zhu, J; Yang, Q; Zhang, M	12/23/2014	5/11/2015	Qilu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=140985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=140985&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51348455	250231187							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
276194	CSCCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O2S/c1-38-12-11-32-16-23-7-10-27(37-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)36-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	SVDARJHLGCNCRG-UHFFFAOYSA-N	140986	US8916574, Compound 3	Epidermal growth factor receptor	Homo sapiens		 56.24						25.00 C	US Patent		10.7270/Q2SX6BXK		aid1800803	US8916574	Wang, J; Fan, C; Zhang, L; Guo, Z; Li, Y; Yang, S; Yan, S; Zhu, J; Yang, Q; Zhang, M	12/23/2014	5/11/2015	Qilu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=140986	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=140986&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51348456	250231188							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
276195	CS(=O)(=O)NCCNCc5ccc(c4ccc3ncnc(Nc2ccc(OCc1cccc(F)c1)c(Cl)c2)c3c4)o5	InChI=1S/C29H27ClFN5O4S/c1-41(37,38)35-12-11-32-16-23-7-10-27(40-23)20-5-8-26-24(14-20)29(34-18-33-26)36-22-6-9-28(25(30)15-22)39-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32,35H,11-12,16-17H2,1H3,(H,33,34,36)	QXBRLYYVUXFWHN-UHFFFAOYSA-N	140987	US8916574, Compound 4	Epidermal growth factor receptor	Homo sapiens		 15.54						25.00 C	US Patent		10.7270/Q2SX6BXK		aid1800803	US8916574	Wang, J; Fan, C; Zhang, L; Guo, Z; Li, Y; Yang, S; Yan, S; Zhu, J; Yang, Q; Zhang, M	12/23/2014	5/11/2015	Qilu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=140987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=140987&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			68155180	250231189							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
276196	Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)-c3ccc(CNCCS(=O)(=O)CC(F)(F)F)o3)cc2Cl)c1	InChI=1S/C30H25ClF4N4O4S/c31-25-14-22(5-8-28(25)42-16-19-2-1-3-21(32)12-19)39-29-24-13-20(4-7-26(24)37-18-38-29)27-9-6-23(43-27)15-36-10-11-44(40,41)17-30(33,34)35/h1-9,12-14,18,36H,10-11,15-17H2,(H,37,38,39)	VPRLBIZASKQOSZ-UHFFFAOYSA-N	140988	US8916574, Compound 5	Epidermal growth factor receptor	Homo sapiens		 14.61						25.00 C	US Patent		10.7270/Q2SX6BXK		aid1800803	US8916574	Wang, J; Fan, C; Zhang, L; Guo, Z; Li, Y; Yang, S; Yan, S; Zhu, J; Yang, Q; Zhang, M	12/23/2014	5/11/2015	Qilu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=140988	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=140988&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51348457	250231190							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
276197	Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)-c3ccc(CNS(=O)(=O)C(F)(F)F)o3)cc2Cl)c1	InChI=1S/C27H19ClF4N4O4S/c28-22-12-19(5-8-25(22)39-14-16-2-1-3-18(29)10-16)36-26-21-11-17(4-7-23(21)33-15-34-26)24-9-6-20(40-24)13-35-41(37,38)27(30,31)32/h1-12,15,35H,13-14H2,(H,33,34,36)	MVVFGYFCZLTASL-UHFFFAOYSA-N	140989	US8916574, Compound 6	Epidermal growth factor receptor	Homo sapiens		 32.4						25.00 C	US Patent		10.7270/Q2SX6BXK		aid1800803	US8916574	Wang, J; Fan, C; Zhang, L; Guo, Z; Li, Y; Yang, S; Yan, S; Zhu, J; Yang, Q; Zhang, M	12/23/2014	5/11/2015	Qilu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=140989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=140989&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91754915	250231191							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287800	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H24F3N5O4/c1-3-22(34)30-16-5-4-6-18(13-16)37-23-19(25(26,27)28)15-29-24(32-23)31-20-8-7-17(14-21(20)35-2)33-9-11-36-12-10-33/h3-8,13-15H,1,9-12H2,2H3,(H,30,34)(H,29,31,32)	NDTRZENFRVHAFZ-UHFFFAOYSA-N	149401	US8975249, I-1::US10434101, Compound I-1::US11096942, Compound I-1	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			67513439	252149356							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287801	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H25F3N6O3/c1-3-22(35)30-16-5-4-6-17(13-16)31-23-19(25(26,27)28)15-29-24(33-23)32-20-8-7-18(14-21(20)36-2)34-9-11-37-12-10-34/h3-8,13-15H,1,9-12H2,2H3,(H,30,35)(H2,29,31,32,33)	WXDGNJJCOMJRLQ-UHFFFAOYSA-N	149402	US8975249, I-2::US10434101, Compound I-2::US11096942, Compound I-2	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335382	252149357							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287802	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO	InChI=1S/C26H27ClN6O5/c1-3-23(35)29-17-5-4-6-19(13-17)38-25-20(27)15-28-26(31-25)30-21-8-7-18(14-22(21)37-2)32-9-11-33(12-10-32)24(36)16-34/h3-8,13-15,34H,1,9-12,16H2,2H3,(H,29,35)(H,28,30,31)	WIKQZNCZVKHLAP-UHFFFAOYSA-N	149403	US8975249, I-3::US10434101, Compound I-3::US11096942, Compound I-3	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335383	252149358							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287803	CC(=O)N1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Nc4cccc(c4)NC(=O)C=C)C(F)(F)F	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	US8975249, I-4::CO-1686::Rociletinib::AVL-301::CNX-419::Tube721::CHEMBL3545308::US10167264, Compound CO-1686::US9783524, CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDL,5XDK	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287804	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H24ClN5O4/c1-3-22(31)27-16-5-4-6-18(13-16)34-23-19(25)15-26-24(29-23)28-20-8-7-17(14-21(20)32-2)30-9-11-33-12-10-30/h3-8,13-15H,1,9-12H2,2H3,(H,27,31)(H,26,28,29)	SGYVANQNHBGWFO-UHFFFAOYSA-N	149405	US8975249, I-15::US8975249, I-5::US10434101, Compound I-5::US11096942, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49820427	252149360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287805	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO	InChI=1S/C27H28F3N7O4/c1-3-23(39)32-17-5-4-6-18(13-17)33-25-20(27(28,29)30)15-31-26(35-25)34-21-8-7-19(14-22(21)41-2)36-9-11-37(12-10-36)24(40)16-38/h3-8,13-15,38H,1,9-12,16H2,2H3,(H,32,39)(H2,31,33,34,35)	PCXGVIRJVAHFKJ-UHFFFAOYSA-N	149406	US8975249, I-6::US10434101, Compound I-6::US11096942, Compound I-6	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149406	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149406&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335533	252149361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287806	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(C)=O	InChI=1S/C28H30F3N7O3/c1-4-25(40)33-19-7-5-8-20(15-19)34-26-22(28(29,30)31)17-32-27(36-26)35-23-10-9-21(16-24(23)41-3)38-12-6-11-37(13-14-38)18(2)39/h4-5,7-10,15-17H,1,6,11-14H2,2-3H3,(H,33,40)(H2,32,34,35,36)	DXLOPZBHQGBEJJ-UHFFFAOYSA-N	149407	US8975249, I-7::US10434101, Compound I-7::US11096942, Compound I-7	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335534	252149362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287807	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H28ClN7O3/c1-4-24(36)29-18-6-5-7-19(14-18)30-25-21(27)16-28-26(32-25)31-22-9-8-20(15-23(22)37-3)34-12-10-33(11-13-34)17(2)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,36)(H2,28,30,31,32)	YNECADZSNDKLQG-UHFFFAOYSA-N	149408	US8975249, I-8::US9796700, Compound I-298::US10434101, Compound I-8::US11096942, Compound I-8	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335536	252149363							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287808	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H27ClN6O4/c1-4-24(35)29-18-6-5-7-20(14-18)37-25-21(27)16-28-26(31-25)30-22-9-8-19(15-23(22)36-3)33-12-10-32(11-13-33)17(2)34/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,35)(H,28,30,31)	XDXTWQGIOKCMIE-UHFFFAOYSA-N	149409	US8975249, I-9::US10434101, Compound I-9::US11096942, Compound I-9	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335535	252149364							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287809	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O	InChI=1S/C27H27F3N6O4/c1-4-24(38)32-18-6-5-7-20(14-18)40-25-21(27(28,29)30)16-31-26(34-25)33-22-9-8-19(15-23(22)39-3)36-12-10-35(11-13-36)17(2)37/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,38)(H,31,33,34)	BKGAQRNSVMXWHB-UHFFFAOYSA-N	149410	US8975249, I-10::US10434101, Compound I-10::US11096942, Compound I-10	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149410	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149410&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336240	252149365							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287810	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO	InChI=1S/C27H27F3N6O5/c1-3-23(38)32-17-5-4-6-19(13-17)41-25-20(27(28,29)30)15-31-26(34-25)33-21-8-7-18(14-22(21)40-2)35-9-11-36(12-10-35)24(39)16-37/h3-8,13-15,37H,1,9-12,16H2,2H3,(H,32,38)(H,31,33,34)	WKEXNNJACJTUAS-UHFFFAOYSA-N	149411	US8975249, I-11::US10434101, Compound I-11::US11096942, Compound I-11	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149411	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335537	252149366							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287811	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO	InChI=1S/C26H28ClN7O4/c1-3-23(36)29-17-5-4-6-18(13-17)30-25-20(27)15-28-26(32-25)31-21-8-7-19(14-22(21)38-2)33-9-11-34(12-10-33)24(37)16-35/h3-8,13-15,35H,1,9-12,16H2,2H3,(H,29,36)(H2,28,30,31,32)	BMMHTJXCXNYDDS-UHFFFAOYSA-N	149412	US8975249, I-12::US10434101, Compound I-12::US11096942, Compound I-12	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149412	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149412&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335674	252149367							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287812	FC(F)Oc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H22F5N5O4/c1-2-21(36)32-15-4-3-5-17(12-15)38-22-18(25(28,29)30)14-31-24(34-22)33-19-7-6-16(13-20(19)39-23(26)27)35-8-10-37-11-9-35/h2-7,12-14,23H,1,8-11H2,(H,32,36)(H,31,33,34)	KUYLULOJVXLEOJ-UHFFFAOYSA-N	149413	US8975249, I-13::US10434101, Compound I-13::US11096942, Compound I-13	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149413	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149413&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335675	252149368							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287813	FC(F)Oc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H23F5N6O3/c1-2-21(37)32-15-4-3-5-16(12-15)33-22-18(25(28,29)30)14-31-24(35-22)34-19-7-6-17(13-20(19)39-23(26)27)36-8-10-38-11-9-36/h2-7,12-14,23H,1,8-11H2,(H,32,37)(H2,31,33,34,35)	AHOJFMYEJUDGPC-UHFFFAOYSA-N	149414	US8975249, I-14::US10434101, Compound I-14::US11096942, Compound I-14	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149414	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149414&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335676	252149369							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287814	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H24ClN5O4/c1-3-22(31)27-16-5-4-6-18(13-16)34-23-19(25)15-26-24(29-23)28-20-8-7-17(14-21(20)32-2)30-9-11-33-12-10-30/h3-8,13-15H,1,9-12H2,2H3,(H,27,31)(H,26,28,29)	SGYVANQNHBGWFO-UHFFFAOYSA-N	149405	US8975249, I-15::US8975249, I-5::US10434101, Compound I-5::US11096942, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49820427	252149360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287815	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C26H28F3N7O4S/c1-4-23(37)31-17-6-5-7-18(14-17)32-24-20(26(27,28)29)16-30-25(34-24)33-21-9-8-19(15-22(21)40-2)35-10-12-36(13-11-35)41(3,38)39/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,37)(H2,30,32,33,34)	SHSKZEADGDUNPX-UHFFFAOYSA-N	149416	US8975249, I-17::US10434101, Compound I-17::US11096942, Compound I-17	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335810	252149370							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287816	CCOc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C30H35ClN6O5/c1-6-26(38)33-20-9-8-10-22(17-20)41-27-23(31)19-32-28(35-27)34-24-12-11-21(18-25(24)40-7-2)36-13-15-37(16-14-36)29(39)42-30(3,4)5/h6,8-12,17-19H,1,7,13-16H2,2-5H3,(H,33,38)(H,32,34,35)	URSWCQCZHBRDPK-UHFFFAOYSA-N	149417	US8975249, I-18::US10434101, Compound I-18::US11096942, Compound I-18	Epidermal growth factor receptor	Homo sapiens		>1000					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335812	252149371							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287817	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)C(F)(F)F	InChI=1S/C28H27F6N7O3/c1-3-23(42)36-17-6-4-7-18(14-17)37-24-20(27(29,30)31)16-35-26(39-24)38-21-9-8-19(15-22(21)44-2)40-10-5-11-41(13-12-40)25(43)28(32,33)34/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,36,42)(H2,35,37,38,39)	XSXWUJOTESYJJR-UHFFFAOYSA-N	149418	US8975249, I-19::US10434101, Compound I-19::US11096942, Compound I-19	Epidermal growth factor receptor	Homo sapiens		 200					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335811	252149372							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287818	COC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H27F3N6O5/c1-4-23(37)32-17-6-5-7-19(14-17)41-24-20(27(28,29)30)16-31-25(34-24)33-21-9-8-18(15-22(21)39-2)35-10-12-36(13-11-35)26(38)40-3/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,37)(H,31,33,34)	HYWICFNCOAZGSB-UHFFFAOYSA-N	149419	US8975249, I-20::US10434101, Compound I-20::US11096942, Compound I-20	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336241	252149373							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287819	CNC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H28F3N7O4/c1-4-23(38)33-17-6-5-7-19(14-17)41-24-20(27(28,29)30)16-32-25(35-24)34-21-9-8-18(15-22(21)40-3)36-10-12-37(13-11-36)26(39)31-2/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,39)(H,33,38)(H,32,34,35)	OZBXOHUAVAGHLZ-UHFFFAOYSA-N	149420	US8975249, I-21::US10434101, Compound I-21::US11096942, Compound I-21	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149420	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149420&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335813	252149374							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287820	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C26H27F3N6O5S/c1-4-23(36)31-17-6-5-7-19(14-17)40-24-20(26(27,28)29)16-30-25(33-24)32-21-9-8-18(15-22(21)39-2)34-10-12-35(13-11-34)41(3,37)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,36)(H,30,32,33)	SNFZHTGBYLFGLP-UHFFFAOYSA-N	149421	US8975249, I-22::US10434101, Compound I-22::US11096942, Compound I-22	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149421&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335814	252149375							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287821	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C30H35ClN6O4/c1-6-26(38)33-20-8-7-9-22(16-20)41-28-23(31)19-32-29(35-28)34-24-11-10-21(17-25(24)40-5)36-12-14-37(15-13-36)27(39)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,33,38)(H,32,34,35)	DECLEZRWEXSBKQ-UHFFFAOYSA-N	149422	US8975249, I-23::US10434101, Compound I-23::US11096942, Compound I-23	Epidermal growth factor receptor	Homo sapiens		 200					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149422	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149422&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335951	252149376							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287822	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)C(F)(F)F	InChI=1S/C26H24ClF3N6O4/c1-3-22(37)32-16-5-4-6-18(13-16)40-23-19(27)15-31-25(34-23)33-20-8-7-17(14-21(20)39-2)35-9-11-36(12-10-35)24(38)26(28,29)30/h3-8,13-15H,1,9-12H2,2H3,(H,32,37)(H,31,33,34)	ZISHQPULHRIZOI-UHFFFAOYSA-N	149423	US8975249, I-24::US10434101, Compound I-24::US11096942, Compound I-24	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149423&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335953	252149377							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287823	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C25H27ClN6O5S/c1-4-23(33)28-17-6-5-7-19(14-17)37-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)36-2)31-10-12-32(13-11-31)38(3,34)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,33)(H,27,29,30)	LXSALHKZTCSKQV-UHFFFAOYSA-N	149424	US8975249, I-26::US10434101, Compound I-26::US11096942, Compound I-26	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149424	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149424&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336242	252149378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287824	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(N)(=O)=O	InChI=1S/C25H26F3N7O5S/c1-3-22(36)31-16-5-4-6-18(13-16)40-23-19(25(26,27)28)15-30-24(33-23)32-20-8-7-17(14-21(20)39-2)34-9-11-35(12-10-34)41(29,37)38/h3-8,13-15H,1,9-12H2,2H3,(H,31,36)(H2,29,37,38)(H,30,32,33)	DSKKGMALLDPGIT-UHFFFAOYSA-N	149425	US8975249, I-27::US10434101, Compound I-27::US11096942, Compound I-27	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149425	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149425&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335954	252149379							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287825	CNC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H29F3N8O3/c1-4-23(39)33-17-6-5-7-18(14-17)34-24-20(27(28,29)30)16-32-25(36-24)35-21-9-8-19(15-22(21)41-3)37-10-12-38(13-11-37)26(40)31-2/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,40)(H,33,39)(H2,32,34,35,36)	QBKCKCBRLDNUCY-UHFFFAOYSA-N	149426	US8975249, I-28::US10434101, Compound I-28::US11096942, Compound I-28	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149426&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335955	252149380							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287826	COC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H28F3N7O4/c1-4-23(38)32-17-6-5-7-18(14-17)33-24-20(27(28,29)30)16-31-25(35-24)34-21-9-8-19(15-22(21)40-2)36-10-12-37(13-11-36)26(39)41-3/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,38)(H2,31,33,34,35)	KHVUCJNBJOOTNT-UHFFFAOYSA-N	149427	US8975249, I-29::US10434101, Compound I-29::US11096942, Compound I-29	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336096	252149381							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287827	OCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)(F)F)c1	InChI=1S/C27H25F6N7O4/c1-2-22(42)35-16-4-3-5-17(12-16)36-24-19(26(28,29)30)14-34-25(38-24)37-20-7-6-18(13-21(20)44-27(31,32)33)39-8-10-40(11-9-39)23(43)15-41/h2-7,12-14,41H,1,8-11,15H2,(H,35,42)(H2,34,36,37,38)	PPOKBGQNCHKPRL-UHFFFAOYSA-N	149428	US8975249, I-30::US10434101, Compound I-30::US11096942, Compound I-30	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336097	252149382							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287828	OCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)F)c1	InChI=1S/C27H26F5N7O4/c1-2-22(41)34-16-4-3-5-17(12-16)35-24-19(27(30,31)32)14-33-26(37-24)36-20-7-6-18(13-21(20)43-25(28)29)38-8-10-39(11-9-38)23(42)15-40/h2-7,12-14,25,40H,1,8-11,15H2,(H,34,41)(H2,33,35,36,37)	DYRCSDCGUVHPRS-UHFFFAOYSA-N	149429	US8975249, I-31::US10434101, Compound I-31::US11096942, Compound I-31	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336098	252149383							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287829	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)F)c1	InChI=1S/C27H26F5N7O3/c1-3-23(41)34-17-5-4-6-18(13-17)35-24-20(27(30,31)32)15-33-26(37-24)36-21-8-7-19(14-22(21)42-25(28)29)39-11-9-38(10-12-39)16(2)40/h3-8,13-15,25H,1,9-12H2,2H3,(H,34,41)(H2,33,35,36,37)	NCFGMTUIORXQEA-UHFFFAOYSA-N	149430	US8975249, I-32::US10434101, Compound I-32::US11096942, Compound I-32	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336099	252149384							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287830	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)(F)F)c1	InChI=1S/C27H25F6N7O3/c1-3-23(42)35-17-5-4-6-18(13-17)36-24-20(26(28,29)30)15-34-25(38-24)37-21-8-7-19(14-22(21)43-27(31,32)33)40-11-9-39(10-12-40)16(2)41/h3-8,13-15H,1,9-12H2,2H3,(H,35,42)(H2,34,36,37,38)	XQFBCBIHUAIWGV-UHFFFAOYSA-N	149431	US8975249, I-33::US10434101, Compound I-33::US11096942, Compound I-33	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336239	252149385							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287831	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)C(C)(C)C	InChI=1S/C30H34F3N7O3/c1-6-25(41)35-19-8-7-9-20(16-19)36-26-22(30(31,32)33)18-34-28(38-26)37-23-11-10-21(17-24(23)43-5)39-12-14-40(15-13-39)27(42)29(2,3)4/h6-11,16-18H,1,12-15H2,2-5H3,(H,35,41)(H2,34,36,37,38)	VSPRQVANTMCJBV-UHFFFAOYSA-N	149432	US8975249, I-34::US10434101, Compound I-34::US11096942, Compound I-34	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149432&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336243	252149386							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287832	CCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C28H30F3N7O3/c1-4-24(39)33-18-7-6-8-19(15-18)34-26-21(28(29,30)31)17-32-27(36-26)35-22-10-9-20(16-23(22)41-3)37-11-13-38(14-12-37)25(40)5-2/h4,6-10,15-17H,1,5,11-14H2,2-3H3,(H,33,39)(H2,32,34,35,36)	NSHHXIZJTQXLQE-UHFFFAOYSA-N	149433	US8975249, I-35::US10434101, Compound I-35::US11096942, Compound I-35	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334019	252149387							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287833	FC(F)Oc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H22ClF2N5O4/c1-2-21(33)29-15-4-3-5-17(12-15)35-22-18(25)14-28-24(31-22)30-19-7-6-16(13-20(19)36-23(26)27)32-8-10-34-11-9-32/h2-7,12-14,23H,1,8-11H2,(H,29,33)(H,28,30,31)	NXBMDDBXMAQAPS-UHFFFAOYSA-N	149434	US8975249, I-36::US10434101, Compound I-36::US11096942, Compound I-36	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149434&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334020	252149388							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287834	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCCOCC1	InChI=1S/C25H26ClN5O4/c1-3-23(32)28-17-6-4-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)33-2)31-10-5-12-34-13-11-31/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,28,32)(H,27,29,30)	FTEJKODFWXJJEP-UHFFFAOYSA-N	149435	US8975249, I-37::US10434101, Compound I-37::US11096942, Compound I-37	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334021	252149389							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287835	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCOCC1	InChI=1S/C26H27F3N6O3/c1-3-23(36)31-17-6-4-7-18(14-17)32-24-20(26(27,28)29)16-30-25(34-24)33-21-9-8-19(15-22(21)37-2)35-10-5-12-38-13-11-35/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,31,36)(H2,30,32,33,34)	CKHWLGJWGNTAIV-UHFFFAOYSA-N	149436	US8975249, I-38::US10434101, Compound I-38::US11096942, Compound I-38	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334022	252149390							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287836	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C31H36F3N7O4/c1-6-26(42)36-20-9-7-10-21(17-20)37-27-23(31(32,33)34)19-35-28(39-27)38-24-12-11-22(18-25(24)44-5)40-13-8-14-41(16-15-40)29(43)45-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,36,42)(H2,35,37,38,39)	WORKLTLCQSPUJP-UHFFFAOYSA-N	149437	US8975249, I-44::US8975249, I-39::US10434101, Compound I-44::US11096942, Compound I-44	Epidermal growth factor receptor	Homo sapiens		>1000					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334181	252149391							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287837	COc1cc(ccc1Nc1ncc(Br)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H28BrN7O3/c1-4-24(36)29-18-6-5-7-19(14-18)30-25-21(27)16-28-26(32-25)31-22-9-8-20(15-23(22)37-3)34-12-10-33(11-13-34)17(2)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,36)(H2,28,30,31,32)	FXJRSQCZSIOFJL-UHFFFAOYSA-N	149438	US8975249, I-40::US10434101, Compound I-40::US11096942, Compound I-40	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334179	252149392							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287838	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C25H28ClN7O4S/c1-4-23(34)28-17-6-5-7-18(14-17)29-24-20(26)16-27-25(31-24)30-21-9-8-19(15-22(21)37-2)32-10-12-33(13-11-32)38(3,35)36/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,34)(H2,27,29,30,31)	SYBJZAZQBBVLFV-UHFFFAOYSA-N	149439	US8975249, I-41::US10434101, Compound I-41::US11096942, Compound I-41	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149439&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334180	252149393							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287839	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C31H35F3N6O4/c1-6-26(41)36-20-8-7-9-22(16-20)44-28-23(31(32,33)34)19-35-29(38-28)37-24-11-10-21(17-25(24)43-5)39-12-14-40(15-13-39)27(42)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,36,41)(H,35,37,38)	PYNFIMQJVVVSBG-UHFFFAOYSA-N	149440	US8975249, I-42::US10434101, Compound I-42::US11096942, Compound I-42	Epidermal growth factor receptor	Homo sapiens		 650					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149440&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			67978922	252149394							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287840	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C30H35ClN6O5/c1-6-26(38)33-20-9-7-10-22(17-20)41-27-23(31)19-32-28(35-27)34-24-12-11-21(18-25(24)40-5)36-13-8-14-37(16-15-36)29(39)42-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,33,38)(H,32,34,35)	FHDQQJPNVWQLDP-UHFFFAOYSA-N	149441	US8975249, I-43::US10434101, Compound I-43::US11096942, Compound I-43	Epidermal growth factor receptor	Homo sapiens		 650					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334183	252149395							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287841	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C31H36F3N7O4/c1-6-26(42)36-20-9-7-10-21(17-20)37-27-23(31(32,33)34)19-35-28(39-27)38-24-12-11-22(18-25(24)44-5)40-13-8-14-41(16-15-40)29(43)45-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,36,42)(H2,35,37,38,39)	WORKLTLCQSPUJP-UHFFFAOYSA-N	149437	US8975249, I-44::US8975249, I-39::US10434101, Compound I-44::US11096942, Compound I-44	Epidermal growth factor receptor	Homo sapiens		 650					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334181	252149391							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287842	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C31H36F3N7O3/c1-6-26(42)36-20-8-7-9-21(16-20)37-28-23(31(32,33)34)19-35-29(39-28)38-24-11-10-22(17-25(24)44-5)40-12-14-41(15-13-40)27(43)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,36,42)(H2,35,37,38,39)	BCSFIPUWAMSZBP-UHFFFAOYSA-N	149443	US8975249, I-45::US10434101, Compound I-45::US11096942, Compound I-45	Epidermal growth factor receptor	Homo sapiens		 65					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			68027150	252149396							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287843	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C29H33ClN6O5/c1-6-25(37)32-19-8-7-9-21(16-19)40-26-22(30)18-31-27(34-26)33-23-11-10-20(17-24(23)39-5)35-12-14-36(15-13-35)28(38)41-29(2,3)4/h6-11,16-18H,1,12-15H2,2-5H3,(H,32,37)(H,31,33,34)	KJCFRHMSJIYOPR-UHFFFAOYSA-N	149444	US8975249, I-46::US10434101, Compound I-46::US11096942, Compound I-46	Epidermal growth factor receptor	Homo sapiens		 200					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334328	252149397							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287844	CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC(F)(F)F)c1	InChI=1S/C29H30ClF3N6O5/c1-5-24(40)35-18-7-6-8-20(15-18)42-25-21(30)17-34-26(37-25)36-22-10-9-19(16-23(22)43-29(31,32)33)38-11-13-39(14-12-38)27(41)44-28(2,3)4/h5-10,15-17H,1,11-14H2,2-4H3,(H,35,40)(H,34,36,37)	CQSIBUGHZLHKBV-UHFFFAOYSA-N	149445	US8975249, I-47::US10434101, Compound I-47::US11096942, Compound I-47	Epidermal growth factor receptor	Homo sapiens		>1000					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334329	252149398							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287845	COC(=O)[C@@H]1CN(CCN1C(C)=O)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1 |r|	InChI=1S/C29H30F3N7O5/c1-5-25(41)34-18-7-6-8-19(13-18)35-26-21(29(30,31)32)15-33-28(37-26)36-22-10-9-20(14-24(22)43-3)38-11-12-39(17(2)40)23(16-38)27(42)44-4/h5-10,13-15,23H,1,11-12,16H2,2-4H3,(H,34,41)(H2,33,35,36,37)	FJEBNLPKFAZSEO-UHFFFAOYSA-N	149446	US8975249, I-48::US10434101, Compound I-48::US11096942, Compound I-48	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334330	252149399							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287846	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCS(=O)(=O)CC1	InChI=1S/C25H25F3N6O4S/c1-3-22(35)30-16-5-4-6-17(13-16)31-23-19(25(26,27)28)15-29-24(33-23)32-20-8-7-18(14-21(20)38-2)34-9-11-39(36,37)12-10-34/h3-8,13-15H,1,9-12H2,2H3,(H,30,35)(H2,29,31,32,33)	ZUMAVVJXTLHREC-UHFFFAOYSA-N	149447	US8975249, I-49::US10434101, Compound I-49::US11096942, Compound I-49	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334476	252149400							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287847	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H24F3N5O4/c1-3-22(34)30-16-5-4-6-18(13-16)37-23-19(25(26,27)28)15-29-24(32-23)31-20-8-7-17(14-21(20)35-2)33-9-11-36-12-10-33/h3-8,13-15H,1,9-12H2,2H3,(H,30,34)(H,29,31,32)	NDTRZENFRVHAFZ-UHFFFAOYSA-N	149401	US8975249, I-1::US10434101, Compound I-1::US11096942, Compound I-1	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			67513439	252149356							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287848	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H25F3N6O3/c1-3-22(35)30-16-5-4-6-17(13-16)31-23-19(25(26,27)28)15-29-24(33-23)32-20-8-7-18(14-21(20)36-2)34-9-11-37-12-10-34/h3-8,13-15H,1,9-12H2,2H3,(H,30,35)(H2,29,31,32,33)	WXDGNJJCOMJRLQ-UHFFFAOYSA-N	149402	US8975249, I-2::US10434101, Compound I-2::US11096942, Compound I-2	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335382	252149357							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287849	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO	InChI=1S/C26H27ClN6O5/c1-3-23(35)29-17-5-4-6-19(13-17)38-25-20(27)15-28-26(31-25)30-21-8-7-18(14-22(21)37-2)32-9-11-33(12-10-32)24(36)16-34/h3-8,13-15,34H,1,9-12,16H2,2H3,(H,29,35)(H,28,30,31)	WIKQZNCZVKHLAP-UHFFFAOYSA-N	149403	US8975249, I-3::US10434101, Compound I-3::US11096942, Compound I-3	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335383	252149358							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287850	CC(=O)N1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Nc4cccc(c4)NC(=O)C=C)C(F)(F)F	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	US8975249, I-4::CO-1686::Rociletinib::AVL-301::CNX-419::Tube721::CHEMBL3545308::US10167264, Compound CO-1686::US9783524, CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDL,5XDK	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287851	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H24ClN5O4/c1-3-22(31)27-16-5-4-6-18(13-16)34-23-19(25)15-26-24(29-23)28-20-8-7-17(14-21(20)32-2)30-9-11-33-12-10-30/h3-8,13-15H,1,9-12H2,2H3,(H,27,31)(H,26,28,29)	SGYVANQNHBGWFO-UHFFFAOYSA-N	149405	US8975249, I-15::US8975249, I-5::US10434101, Compound I-5::US11096942, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49820427	252149360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287852	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO	InChI=1S/C27H28F3N7O4/c1-3-23(39)32-17-5-4-6-18(13-17)33-25-20(27(28,29)30)15-31-26(35-25)34-21-8-7-19(14-22(21)41-2)36-9-11-37(12-10-36)24(40)16-38/h3-8,13-15,38H,1,9-12,16H2,2H3,(H,32,39)(H2,31,33,34,35)	PCXGVIRJVAHFKJ-UHFFFAOYSA-N	149406	US8975249, I-6::US10434101, Compound I-6::US11096942, Compound I-6	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149406	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149406&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335533	252149361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287853	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(C)=O	InChI=1S/C28H30F3N7O3/c1-4-25(40)33-19-7-5-8-20(15-19)34-26-22(28(29,30)31)17-32-27(36-26)35-23-10-9-21(16-24(23)41-3)38-12-6-11-37(13-14-38)18(2)39/h4-5,7-10,15-17H,1,6,11-14H2,2-3H3,(H,33,40)(H2,32,34,35,36)	DXLOPZBHQGBEJJ-UHFFFAOYSA-N	149407	US8975249, I-7::US10434101, Compound I-7::US11096942, Compound I-7	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335534	252149362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287854	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H28ClN7O3/c1-4-24(36)29-18-6-5-7-19(14-18)30-25-21(27)16-28-26(32-25)31-22-9-8-20(15-23(22)37-3)34-12-10-33(11-13-34)17(2)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,36)(H2,28,30,31,32)	YNECADZSNDKLQG-UHFFFAOYSA-N	149408	US8975249, I-8::US9796700, Compound I-298::US10434101, Compound I-8::US11096942, Compound I-8	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335536	252149363							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287855	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H27ClN6O4/c1-4-24(35)29-18-6-5-7-20(14-18)37-25-21(27)16-28-26(31-25)30-22-9-8-19(15-23(22)36-3)33-12-10-32(11-13-33)17(2)34/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,35)(H,28,30,31)	XDXTWQGIOKCMIE-UHFFFAOYSA-N	149409	US8975249, I-9::US10434101, Compound I-9::US11096942, Compound I-9	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335535	252149364							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287856	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O	InChI=1S/C27H27F3N6O4/c1-4-24(38)32-18-6-5-7-20(14-18)40-25-21(27(28,29)30)16-31-26(34-25)33-22-9-8-19(15-23(22)39-3)36-12-10-35(11-13-36)17(2)37/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,38)(H,31,33,34)	BKGAQRNSVMXWHB-UHFFFAOYSA-N	149410	US8975249, I-10::US10434101, Compound I-10::US11096942, Compound I-10	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149410	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149410&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336240	252149365							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287857	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO	InChI=1S/C27H27F3N6O5/c1-3-23(38)32-17-5-4-6-19(13-17)41-25-20(27(28,29)30)15-31-26(34-25)33-21-8-7-18(14-22(21)40-2)35-9-11-36(12-10-35)24(39)16-37/h3-8,13-15,37H,1,9-12,16H2,2H3,(H,32,38)(H,31,33,34)	WKEXNNJACJTUAS-UHFFFAOYSA-N	149411	US8975249, I-11::US10434101, Compound I-11::US11096942, Compound I-11	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149411	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335537	252149366							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287858	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO	InChI=1S/C26H28ClN7O4/c1-3-23(36)29-17-5-4-6-18(13-17)30-25-20(27)15-28-26(32-25)31-21-8-7-19(14-22(21)38-2)33-9-11-34(12-10-33)24(37)16-35/h3-8,13-15,35H,1,9-12,16H2,2H3,(H,29,36)(H2,28,30,31,32)	BMMHTJXCXNYDDS-UHFFFAOYSA-N	149412	US8975249, I-12::US10434101, Compound I-12::US11096942, Compound I-12	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149412	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149412&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335674	252149367							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287859	FC(F)Oc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H22F5N5O4/c1-2-21(36)32-15-4-3-5-17(12-15)38-22-18(25(28,29)30)14-31-24(34-22)33-19-7-6-16(13-20(19)39-23(26)27)35-8-10-37-11-9-35/h2-7,12-14,23H,1,8-11H2,(H,32,36)(H,31,33,34)	KUYLULOJVXLEOJ-UHFFFAOYSA-N	149413	US8975249, I-13::US10434101, Compound I-13::US11096942, Compound I-13	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149413	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149413&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335675	252149368							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287860	FC(F)Oc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H23F5N6O3/c1-2-21(37)32-15-4-3-5-16(12-15)33-22-18(25(28,29)30)14-31-24(35-22)34-19-7-6-17(13-20(19)39-23(26)27)36-8-10-38-11-9-36/h2-7,12-14,23H,1,8-11H2,(H,32,37)(H2,31,33,34,35)	AHOJFMYEJUDGPC-UHFFFAOYSA-N	149414	US8975249, I-14::US10434101, Compound I-14::US11096942, Compound I-14	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149414	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149414&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335676	252149369							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287861	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H24ClN5O4/c1-3-22(31)27-16-5-4-6-18(13-16)34-23-19(25)15-26-24(29-23)28-20-8-7-17(14-21(20)32-2)30-9-11-33-12-10-30/h3-8,13-15H,1,9-12H2,2H3,(H,27,31)(H,26,28,29)	SGYVANQNHBGWFO-UHFFFAOYSA-N	149405	US8975249, I-15::US8975249, I-5::US10434101, Compound I-5::US11096942, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49820427	252149360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287862	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C26H28F3N7O4S/c1-4-23(37)31-17-6-5-7-18(14-17)32-24-20(26(27,28)29)16-30-25(34-24)33-21-9-8-19(15-22(21)40-2)35-10-12-36(13-11-35)41(3,38)39/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,37)(H2,30,32,33,34)	SHSKZEADGDUNPX-UHFFFAOYSA-N	149416	US8975249, I-17::US10434101, Compound I-17::US11096942, Compound I-17	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335810	252149370							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287863	CCOc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C30H35ClN6O5/c1-6-26(38)33-20-9-8-10-22(17-20)41-27-23(31)19-32-28(35-27)34-24-12-11-21(18-25(24)40-7-2)36-13-15-37(16-14-36)29(39)42-30(3,4)5/h6,8-12,17-19H,1,7,13-16H2,2-5H3,(H,33,38)(H,32,34,35)	URSWCQCZHBRDPK-UHFFFAOYSA-N	149417	US8975249, I-18::US10434101, Compound I-18::US11096942, Compound I-18	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335812	252149371							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287864	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)C(F)(F)F	InChI=1S/C28H27F6N7O3/c1-3-23(42)36-17-6-4-7-18(14-17)37-24-20(27(29,30)31)16-35-26(39-24)38-21-9-8-19(15-22(21)44-2)40-10-5-11-41(13-12-40)25(43)28(32,33)34/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,36,42)(H2,35,37,38,39)	XSXWUJOTESYJJR-UHFFFAOYSA-N	149418	US8975249, I-19::US10434101, Compound I-19::US11096942, Compound I-19	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335811	252149372							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287865	COC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H27F3N6O5/c1-4-23(37)32-17-6-5-7-19(14-17)41-24-20(27(28,29)30)16-31-25(34-24)33-21-9-8-18(15-22(21)39-2)35-10-12-36(13-11-35)26(38)40-3/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,37)(H,31,33,34)	HYWICFNCOAZGSB-UHFFFAOYSA-N	149419	US8975249, I-20::US10434101, Compound I-20::US11096942, Compound I-20	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336241	252149373							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287866	CNC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H28F3N7O4/c1-4-23(38)33-17-6-5-7-19(14-17)41-24-20(27(28,29)30)16-32-25(35-24)34-21-9-8-18(15-22(21)40-3)36-10-12-37(13-11-36)26(39)31-2/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,39)(H,33,38)(H,32,34,35)	OZBXOHUAVAGHLZ-UHFFFAOYSA-N	149420	US8975249, I-21::US10434101, Compound I-21::US11096942, Compound I-21	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149420	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149420&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335813	252149374							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287867	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C26H27F3N6O5S/c1-4-23(36)31-17-6-5-7-19(14-17)40-24-20(26(27,28)29)16-30-25(33-24)32-21-9-8-18(15-22(21)39-2)34-10-12-35(13-11-34)41(3,37)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,36)(H,30,32,33)	SNFZHTGBYLFGLP-UHFFFAOYSA-N	149421	US8975249, I-22::US10434101, Compound I-22::US11096942, Compound I-22	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149421&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335814	252149375							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287868	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C30H35ClN6O4/c1-6-26(38)33-20-8-7-9-22(16-20)41-28-23(31)19-32-29(35-28)34-24-11-10-21(17-25(24)40-5)36-12-14-37(15-13-36)27(39)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,33,38)(H,32,34,35)	DECLEZRWEXSBKQ-UHFFFAOYSA-N	149422	US8975249, I-23::US10434101, Compound I-23::US11096942, Compound I-23	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149422	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149422&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335951	252149376							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287869	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)C(F)(F)F	InChI=1S/C26H24ClF3N6O4/c1-3-22(37)32-16-5-4-6-18(13-16)40-23-19(27)15-31-25(34-23)33-20-8-7-17(14-21(20)39-2)35-9-11-36(12-10-35)24(38)26(28,29)30/h3-8,13-15H,1,9-12H2,2H3,(H,32,37)(H,31,33,34)	ZISHQPULHRIZOI-UHFFFAOYSA-N	149423	US8975249, I-24::US10434101, Compound I-24::US11096942, Compound I-24	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149423&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335953	252149377							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287870	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C25H27ClN6O5S/c1-4-23(33)28-17-6-5-7-19(14-17)37-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)36-2)31-10-12-32(13-11-31)38(3,34)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,33)(H,27,29,30)	LXSALHKZTCSKQV-UHFFFAOYSA-N	149424	US8975249, I-26::US10434101, Compound I-26::US11096942, Compound I-26	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149424	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149424&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336242	252149378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287871	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(N)(=O)=O	InChI=1S/C25H26F3N7O5S/c1-3-22(36)31-16-5-4-6-18(13-16)40-23-19(25(26,27)28)15-30-24(33-23)32-20-8-7-17(14-21(20)39-2)34-9-11-35(12-10-34)41(29,37)38/h3-8,13-15H,1,9-12H2,2H3,(H,31,36)(H2,29,37,38)(H,30,32,33)	DSKKGMALLDPGIT-UHFFFAOYSA-N	149425	US8975249, I-27::US10434101, Compound I-27::US11096942, Compound I-27	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149425	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149425&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335954	252149379							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287872	CNC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H29F3N8O3/c1-4-23(39)33-17-6-5-7-18(14-17)34-24-20(27(28,29)30)16-32-25(36-24)35-21-9-8-19(15-22(21)41-3)37-10-12-38(13-11-37)26(40)31-2/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,40)(H,33,39)(H2,32,34,35,36)	QBKCKCBRLDNUCY-UHFFFAOYSA-N	149426	US8975249, I-28::US10434101, Compound I-28::US11096942, Compound I-28	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149426&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335955	252149380							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287873	COC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H28F3N7O4/c1-4-23(38)32-17-6-5-7-18(14-17)33-24-20(27(28,29)30)16-31-25(35-24)34-21-9-8-19(15-22(21)40-2)36-10-12-37(13-11-36)26(39)41-3/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,38)(H2,31,33,34,35)	KHVUCJNBJOOTNT-UHFFFAOYSA-N	149427	US8975249, I-29::US10434101, Compound I-29::US11096942, Compound I-29	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336096	252149381							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287874	OCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)(F)F)c1	InChI=1S/C27H25F6N7O4/c1-2-22(42)35-16-4-3-5-17(12-16)36-24-19(26(28,29)30)14-34-25(38-24)37-20-7-6-18(13-21(20)44-27(31,32)33)39-8-10-40(11-9-39)23(43)15-41/h2-7,12-14,41H,1,8-11,15H2,(H,35,42)(H2,34,36,37,38)	PPOKBGQNCHKPRL-UHFFFAOYSA-N	149428	US8975249, I-30::US10434101, Compound I-30::US11096942, Compound I-30	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336097	252149382							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287875	OCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)F)c1	InChI=1S/C27H26F5N7O4/c1-2-22(41)34-16-4-3-5-17(12-16)35-24-19(27(30,31)32)14-33-26(37-24)36-20-7-6-18(13-21(20)43-25(28)29)38-8-10-39(11-9-38)23(42)15-40/h2-7,12-14,25,40H,1,8-11,15H2,(H,34,41)(H2,33,35,36,37)	DYRCSDCGUVHPRS-UHFFFAOYSA-N	149429	US8975249, I-31::US10434101, Compound I-31::US11096942, Compound I-31	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336098	252149383							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287876	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)F)c1	InChI=1S/C27H26F5N7O3/c1-3-23(41)34-17-5-4-6-18(13-17)35-24-20(27(30,31)32)15-33-26(37-24)36-21-8-7-19(14-22(21)42-25(28)29)39-11-9-38(10-12-39)16(2)40/h3-8,13-15,25H,1,9-12H2,2H3,(H,34,41)(H2,33,35,36,37)	NCFGMTUIORXQEA-UHFFFAOYSA-N	149430	US8975249, I-32::US10434101, Compound I-32::US11096942, Compound I-32	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336099	252149384							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287877	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)(F)F)c1	InChI=1S/C27H25F6N7O3/c1-3-23(42)35-17-5-4-6-18(13-17)36-24-20(26(28,29)30)15-34-25(38-24)37-21-8-7-19(14-22(21)43-27(31,32)33)40-11-9-39(10-12-40)16(2)41/h3-8,13-15H,1,9-12H2,2H3,(H,35,42)(H2,34,36,37,38)	XQFBCBIHUAIWGV-UHFFFAOYSA-N	149431	US8975249, I-33::US10434101, Compound I-33::US11096942, Compound I-33	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336239	252149385							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287878	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)C(C)(C)C	InChI=1S/C30H34F3N7O3/c1-6-25(41)35-19-8-7-9-20(16-19)36-26-22(30(31,32)33)18-34-28(38-26)37-23-11-10-21(17-24(23)43-5)39-12-14-40(15-13-39)27(42)29(2,3)4/h6-11,16-18H,1,12-15H2,2-5H3,(H,35,41)(H2,34,36,37,38)	VSPRQVANTMCJBV-UHFFFAOYSA-N	149432	US8975249, I-34::US10434101, Compound I-34::US11096942, Compound I-34	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149432&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336243	252149386							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287879	CCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C28H30F3N7O3/c1-4-24(39)33-18-7-6-8-19(15-18)34-26-21(28(29,30)31)17-32-27(36-26)35-22-10-9-20(16-23(22)41-3)37-11-13-38(14-12-37)25(40)5-2/h4,6-10,15-17H,1,5,11-14H2,2-3H3,(H,33,39)(H2,32,34,35,36)	NSHHXIZJTQXLQE-UHFFFAOYSA-N	149433	US8975249, I-35::US10434101, Compound I-35::US11096942, Compound I-35	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334019	252149387							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287880	FC(F)Oc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H22ClF2N5O4/c1-2-21(33)29-15-4-3-5-17(12-15)35-22-18(25)14-28-24(31-22)30-19-7-6-16(13-20(19)36-23(26)27)32-8-10-34-11-9-32/h2-7,12-14,23H,1,8-11H2,(H,29,33)(H,28,30,31)	NXBMDDBXMAQAPS-UHFFFAOYSA-N	149434	US8975249, I-36::US10434101, Compound I-36::US11096942, Compound I-36	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149434&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334020	252149388							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287881	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCCOCC1	InChI=1S/C25H26ClN5O4/c1-3-23(32)28-17-6-4-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)33-2)31-10-5-12-34-13-11-31/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,28,32)(H,27,29,30)	FTEJKODFWXJJEP-UHFFFAOYSA-N	149435	US8975249, I-37::US10434101, Compound I-37::US11096942, Compound I-37	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334021	252149389							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287882	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCOCC1	InChI=1S/C26H27F3N6O3/c1-3-23(36)31-17-6-4-7-18(14-17)32-24-20(26(27,28)29)16-30-25(34-24)33-21-9-8-19(15-22(21)37-2)35-10-5-12-38-13-11-35/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,31,36)(H2,30,32,33,34)	CKHWLGJWGNTAIV-UHFFFAOYSA-N	149436	US8975249, I-38::US10434101, Compound I-38::US11096942, Compound I-38	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334022	252149390							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287883	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C31H36F3N7O4/c1-6-26(42)36-20-9-7-10-21(17-20)37-27-23(31(32,33)34)19-35-28(39-27)38-24-12-11-22(18-25(24)44-5)40-13-8-14-41(16-15-40)29(43)45-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,36,42)(H2,35,37,38,39)	WORKLTLCQSPUJP-UHFFFAOYSA-N	149437	US8975249, I-44::US8975249, I-39::US10434101, Compound I-44::US11096942, Compound I-44	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334181	252149391							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287884	COc1cc(ccc1Nc1ncc(Br)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H28BrN7O3/c1-4-24(36)29-18-6-5-7-19(14-18)30-25-21(27)16-28-26(32-25)31-22-9-8-20(15-23(22)37-3)34-12-10-33(11-13-34)17(2)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,36)(H2,28,30,31,32)	FXJRSQCZSIOFJL-UHFFFAOYSA-N	149438	US8975249, I-40::US10434101, Compound I-40::US11096942, Compound I-40	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334179	252149392							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287885	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C25H28ClN7O4S/c1-4-23(34)28-17-6-5-7-18(14-17)29-24-20(26)16-27-25(31-24)30-21-9-8-19(15-22(21)37-2)32-10-12-33(13-11-32)38(3,35)36/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,34)(H2,27,29,30,31)	SYBJZAZQBBVLFV-UHFFFAOYSA-N	149439	US8975249, I-41::US10434101, Compound I-41::US11096942, Compound I-41	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149439&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334180	252149393							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287886	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C31H35F3N6O4/c1-6-26(41)36-20-8-7-9-22(16-20)44-28-23(31(32,33)34)19-35-29(38-28)37-24-11-10-21(17-25(24)43-5)39-12-14-40(15-13-39)27(42)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,36,41)(H,35,37,38)	PYNFIMQJVVVSBG-UHFFFAOYSA-N	149440	US8975249, I-42::US10434101, Compound I-42::US11096942, Compound I-42	Epidermal growth factor receptor	Homo sapiens		 650					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149440&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			67978922	252149394							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287887	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C30H35ClN6O5/c1-6-26(38)33-20-9-7-10-22(17-20)41-27-23(31)19-32-28(35-27)34-24-12-11-21(18-25(24)40-5)36-13-8-14-37(16-15-36)29(39)42-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,33,38)(H,32,34,35)	FHDQQJPNVWQLDP-UHFFFAOYSA-N	149441	US8975249, I-43::US10434101, Compound I-43::US11096942, Compound I-43	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334183	252149395							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287888	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C31H36F3N7O4/c1-6-26(42)36-20-9-7-10-21(17-20)37-27-23(31(32,33)34)19-35-28(39-27)38-24-12-11-22(18-25(24)44-5)40-13-8-14-41(16-15-40)29(43)45-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,36,42)(H2,35,37,38,39)	WORKLTLCQSPUJP-UHFFFAOYSA-N	149437	US8975249, I-44::US8975249, I-39::US10434101, Compound I-44::US11096942, Compound I-44	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334181	252149391							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287889	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C31H36F3N7O3/c1-6-26(42)36-20-8-7-9-21(16-20)37-28-23(31(32,33)34)19-35-29(39-28)38-24-11-10-22(17-25(24)44-5)40-12-14-41(15-13-40)27(43)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,36,42)(H2,35,37,38,39)	BCSFIPUWAMSZBP-UHFFFAOYSA-N	149443	US8975249, I-45::US10434101, Compound I-45::US11096942, Compound I-45	Epidermal growth factor receptor	Homo sapiens		 5.5					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			68027150	252149396							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287890	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C29H33ClN6O5/c1-6-25(37)32-19-8-7-9-21(16-19)40-26-22(30)18-31-27(34-26)33-23-11-10-20(17-24(23)39-5)35-12-14-36(15-13-35)28(38)41-29(2,3)4/h6-11,16-18H,1,12-15H2,2-5H3,(H,32,37)(H,31,33,34)	KJCFRHMSJIYOPR-UHFFFAOYSA-N	149444	US8975249, I-46::US10434101, Compound I-46::US11096942, Compound I-46	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334328	252149397							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287891	CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC(F)(F)F)c1	InChI=1S/C29H30ClF3N6O5/c1-5-24(40)35-18-7-6-8-20(15-18)42-25-21(30)17-34-26(37-25)36-22-10-9-19(16-23(22)43-29(31,32)33)38-11-13-39(14-12-38)27(41)44-28(2,3)4/h5-10,15-17H,1,11-14H2,2-4H3,(H,35,40)(H,34,36,37)	CQSIBUGHZLHKBV-UHFFFAOYSA-N	149445	US8975249, I-47::US10434101, Compound I-47::US11096942, Compound I-47	Epidermal growth factor receptor	Homo sapiens		 20					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334329	252149398							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287892	COC(=O)[C@@H]1CN(CCN1C(C)=O)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1 |r|	InChI=1S/C29H30F3N7O5/c1-5-25(41)34-18-7-6-8-19(13-18)35-26-21(29(30,31)32)15-33-28(37-26)36-22-10-9-20(14-24(22)43-3)38-11-12-39(17(2)40)23(16-38)27(42)44-4/h5-10,13-15,23H,1,11-12,16H2,2-4H3,(H,34,41)(H2,33,35,36,37)	FJEBNLPKFAZSEO-UHFFFAOYSA-N	149446	US8975249, I-48::US10434101, Compound I-48::US11096942, Compound I-48	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334330	252149399							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
287893	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCS(=O)(=O)CC1	InChI=1S/C25H25F3N6O4S/c1-3-22(35)30-16-5-4-6-17(13-16)31-23-19(25(26,27)28)15-29-24(33-23)32-20-8-7-18(14-21(20)38-2)34-9-11-39(36,37)12-10-34/h3-8,13-15H,1,9-12H2,2H3,(H,30,35)(H2,29,31,32,33)	ZUMAVVJXTLHREC-UHFFFAOYSA-N	149447	US8975249, I-49::US10434101, Compound I-49::US11096942, Compound I-49	Epidermal growth factor receptor	Homo sapiens		<1					7.5000		US Patent		10.7270/Q22V2DVS		aid1800956	US8975249	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	3/10/2015	8/3/2015	Celgene Avilomics Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334476	252149400							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311806	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccccc1	InChI=1S/C21H24N4O2/c26-18(15-27-21-19-8-4-5-9-20(19)22-16-23-21)14-24-10-12-25(13-11-24)17-6-2-1-3-7-17/h1-9,16,18,26H,10-15H2	WEDMVAMOHXVMLB-UHFFFAOYSA-N	167945	1-(4-Phenylpiperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3a)	Epidermal growth factor receptor	Homo sapiens		 399.63					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167945	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167945&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796621	312525359							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311807	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccccc1Cl	InChI=1S/C21H23ClN4O2/c22-18-6-2-4-8-20(18)26-11-9-25(10-12-26)13-16(27)14-28-21-17-5-1-3-7-19(17)23-15-24-21/h1-8,15-16,27H,9-14H2	FDSOODAZYPJSDK-UHFFFAOYSA-N	167946	1-(4-(2-Chlorophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3b)	Epidermal growth factor receptor	Homo sapiens		 417.61					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167946	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167946&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796622	312525360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311808	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1cccc(Cl)c1	InChI=1S/C21H23ClN4O2/c22-16-4-3-5-17(12-16)26-10-8-25(9-11-26)13-18(27)14-28-21-19-6-1-2-7-20(19)23-15-24-21/h1-7,12,15,18,27H,8-11,13-14H2	PBVMZTYHLDTQAD-UHFFFAOYSA-N	167947	1-(4-(3-Chlorophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3c)	Epidermal growth factor receptor	Homo sapiens		 412.87					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167947	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167947&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796623	312525361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311809	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccccc1F	InChI=1S/C21H23FN4O2/c22-18-6-2-4-8-20(18)26-11-9-25(10-12-26)13-16(27)14-28-21-17-5-1-3-7-19(17)23-15-24-21/h1-8,15-16,27H,9-14H2	KFGMUASCSOBKRG-UHFFFAOYSA-N	167948	1-(4-(2-Fluorophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3d)	Epidermal growth factor receptor	Homo sapiens		 408.51					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167948	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167948&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796624	312525362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311810	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccc(F)cc1	InChI=1S/C21H23FN4O2/c22-16-5-7-17(8-6-16)26-11-9-25(10-12-26)13-18(27)14-28-21-19-3-1-2-4-20(19)23-15-24-21/h1-8,15,18,27H,9-14H2	BZBBEQZGZCRHQF-UHFFFAOYSA-N	167949	1-(4-(4-Fluorophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3e)	Epidermal growth factor receptor	Homo sapiens		 403.12					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167949	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167949&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796625	312525363							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311811	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C21H23N5O4/c27-18(14-30-21-19-3-1-2-4-20(19)22-15-23-21)13-24-9-11-25(12-10-24)16-5-7-17(8-6-16)26(28)29/h1-8,15,18,27H,9-14H2	LDYXRYLRGPOXCN-UHFFFAOYSA-N	167950	1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3f)	Epidermal growth factor receptor	Homo sapiens		 381.94					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167950&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796626	312525364							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311812	COc1ccccc1N1CCN(CC(O)COc2ncnc3ccccc23)CC1	InChI=1S/C22H26N4O3/c1-28-21-9-5-4-8-20(21)26-12-10-25(11-13-26)14-17(27)15-29-22-18-6-2-3-7-19(18)23-16-24-22/h2-9,16-17,27H,10-15H2,1H3	XTGBRYIIOQFQBY-UHFFFAOYSA-N	167951	1-(4-(2-Methoxyphenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3g)	Epidermal growth factor receptor	Homo sapiens		 356.78					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167951	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167951&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796627	312525365							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311813	COc1cccc(c1)N1CCN(CC(O)COc2ncnc3ccccc23)CC1	InChI=1S/C22H26N4O3/c1-28-19-6-4-5-17(13-19)26-11-9-25(10-12-26)14-18(27)15-29-22-20-7-2-3-8-21(20)23-16-24-22/h2-8,13,16,18,27H,9-12,14-15H2,1H3	NQWHKZFLRJPUMS-UHFFFAOYSA-N	167952	1-(4-(3-Methoxyphenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3h)	Epidermal growth factor receptor	Homo sapiens		 208.43					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167952	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167952&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796628	312525366							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311814	COc1ccc(cc1)N1CCN(CC(O)COc2ncnc3ccccc23)CC1	InChI=1S/C22H26N4O3/c1-28-19-8-6-17(7-9-19)26-12-10-25(11-13-26)14-18(27)15-29-22-20-4-2-3-5-21(20)23-16-24-22/h2-9,16,18,27H,10-15H2,1H3	UGSJIBBLYLHNRN-UHFFFAOYSA-N	167953	1-(4-(4-Methoxyphenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3i)	Epidermal growth factor receptor	Homo sapiens		 276.12					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167953&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796629	312525367							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311815	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1cccc(c1)C(F)(F)F	InChI=1S/C22H23F3N4O2/c23-22(24,25)16-4-3-5-17(12-16)29-10-8-28(9-11-29)13-18(30)14-31-21-19-6-1-2-7-20(19)26-15-27-21/h1-7,12,15,18,30H,8-11,13-14H2	ZYCGVUUIDVXHPY-UHFFFAOYSA-N	167954	1-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3j)	Epidermal growth factor receptor	Homo sapiens		 306.91					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167954	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167954&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796630	312525368							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311816	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1cccc(Cl)c1Cl	InChI=1S/C21H22Cl2N4O2/c22-17-5-3-7-19(20(17)23)27-10-8-26(9-11-27)12-15(28)13-29-21-16-4-1-2-6-18(16)24-14-25-21/h1-7,14-15,28H,8-13H2	RYKBULXCTATJCV-UHFFFAOYSA-N	167955	1-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3k)	Epidermal growth factor receptor	Homo sapiens		 409.11					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167955	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167955&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796631	312525369							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311817	OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccc(Cl)c(Cl)c1	InChI=1S/C21H22Cl2N4O2/c22-18-6-5-15(11-19(18)23)27-9-7-26(8-10-27)12-16(28)13-29-21-17-3-1-2-4-20(17)24-14-25-21/h1-6,11,14,16,28H,7-10,12-13H2	JRAVSSVQUHVZMC-UHFFFAOYSA-N	167956	1-(4-(3,4-Dichlorophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3l)	Epidermal growth factor receptor	Homo sapiens		 343.52					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167956&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796632	312525370							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311818	Cc1ccc(N2CCN(CC(O)COc3ncnc4ccccc34)CC2)c(C)c1	InChI=1S/C23H28N4O2/c1-17-7-8-22(18(2)13-17)27-11-9-26(10-12-27)14-19(28)15-29-23-20-5-3-4-6-21(20)24-16-25-23/h3-8,13,16,19,28H,9-12,14-15H2,1-2H3	XXURFXAKIUOJDN-UHFFFAOYSA-N	167957	1-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3m)	Epidermal growth factor receptor	Homo sapiens		 394.82					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167957&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796633	312525371							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311819	OC(COc1ncnc2ccccc12)CN1CCN(Cc2ccccc2)CC1	InChI=1S/C22H26N4O2/c27-19(16-28-22-20-8-4-5-9-21(20)23-17-24-22)15-26-12-10-25(11-13-26)14-18-6-2-1-3-7-18/h1-9,17,19,27H,10-16H2	GJRDMRRBRLWIMA-UHFFFAOYSA-N	167958	1-(4-Benzylpiperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3n)	Epidermal growth factor receptor	Homo sapiens		 434.79					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167958	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167958&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796634	312525372							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311820	CN1CCN(CC(O)COc2ncnc3ccccc23)CC1	InChI=1S/C16H22N4O2/c1-19-6-8-20(9-7-19)10-13(21)11-22-16-14-4-2-3-5-15(14)17-12-18-16/h2-5,12-13,21H,6-11H2,1H3	NZLWNFZAMQUOSN-UHFFFAOYSA-N	167959	1-(4-Methylpiperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3o)	Epidermal growth factor receptor	Homo sapiens		 474.32					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167959&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796635	312525373							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311821	CCN1CCN(CC(O)COc2ncnc3ccccc23)CC1	InChI=1S/C17H24N4O2/c1-2-20-7-9-21(10-8-20)11-14(22)12-23-17-15-5-3-4-6-16(15)18-13-19-17/h3-6,13-14,22H,2,7-12H2,1H3	CAQCMXFJWJJJLH-UHFFFAOYSA-N	167960	1-(4-Ethylpiperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3p)	Epidermal growth factor receptor	Homo sapiens		 461.54					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167960&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796636	312525374							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311822	CN(C)CC(O)COc1ncnc2ccccc12	InChI=1S/C13H17N3O2/c1-16(2)7-10(17)8-18-13-11-5-3-4-6-12(11)14-9-15-13/h3-6,9-10,17H,7-8H2,1-2H3	UXXWCLFQFHSDIF-UHFFFAOYSA-N	167961	1-(Dimethylamino)-3-(quinazolin-4-yloxy)propan-2-ol (3q)	Epidermal growth factor receptor	Homo sapiens		 454.83					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167961&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			12237537	312525375							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311823	OC(COc1ncnc2ccccc12)CN1CCOCC1	InChI=1S/C15H19N3O3/c19-12(9-18-5-7-20-8-6-18)10-21-15-13-3-1-2-4-14(13)16-11-17-15/h1-4,11-12,19H,5-10H2	SUXXKYXDLFQQTP-UHFFFAOYSA-N	167962	1-Morpholino-3-(quinazolin-4-yloxy)propan-2-ol (3r)	Epidermal growth factor receptor	Homo sapiens		 482.86					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167962&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			12237547	312525376							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311824	OC(COc1ncnc2ccccc12)CN1CCCCC1	InChI=1S/C16H21N3O2/c20-13(10-19-8-4-1-5-9-19)11-21-16-14-6-2-3-7-15(14)17-12-18-16/h2-3,6-7,12-13,20H,1,4-5,8-11H2	ZZZNJDODCKXBLN-UHFFFAOYSA-N	167963	1-(Piperidin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3s)	Epidermal growth factor receptor	Homo sapiens		 473.58					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167963	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167963&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			12237545	312525377							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311825	OC(COc1ncnc2ccccc12)Cn1ccnc1	InChI=1S/C14H14N4O2/c19-11(7-18-6-5-15-10-18)8-20-14-12-3-1-2-4-13(12)16-9-17-14/h1-6,9-11,19H,7-8H2	KTWJKWUVFXXMTI-UHFFFAOYSA-N	167964	1-(1H-Imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3t)	Epidermal growth factor receptor	Homo sapiens		 483.26					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167964&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796637	312525378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311826	Cc1nccn1CC(O)COc1ncnc2ccccc12	InChI=1S/C15H16N4O2/c1-11-16-6-7-19(11)8-12(20)9-21-15-13-4-2-3-5-14(13)17-10-18-15/h2-7,10,12,20H,8-9H2,1H3	XTCMHHNUPIPYQB-UHFFFAOYSA-N	167965	1-(2-Methyl-1H-imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3u)	Epidermal growth factor receptor	Homo sapiens		 443.95					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167965&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796638	312525379							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311827	Cc1cn(CC(O)COc2ncnc3ccccc23)cn1	InChI=1S/C15H16N4O2/c1-11-6-19(10-18-11)7-12(20)8-21-15-13-4-2-3-5-14(13)16-9-17-15/h2-6,9-10,12,20H,7-8H2,1H3	NRKBLKNBNMFJGW-UHFFFAOYSA-N	167966	1-(4-Methyl-1H-imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3v)	Epidermal growth factor receptor	Homo sapiens		 451.84					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=167966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=167966&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118796639	312525380							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
311828	COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC	InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)	SPMVMDHWKHCIDT-UHFFFAOYSA-N	50331095	Tivozanib::CHEMBL1289494::US10464902, Tivozanib	Epidermal growth factor receptor	Homo sapiens		 123.64					7.2000	25.00 C	Curated from the literature by BindingDB	10.1111/cbdd.12596	10.7270/Q2GB22TR	26032487	aid1801412		Yin, Y; Sha, S; Wang, YT; Wu, X; Wang, SF; Qiao, F; Lv, PC; Zhu, HL	11/28/2015	3/3/2016	Nanjing University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50331095	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50331095&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9911830	123110210		CHEMBL1289494					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314489	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C27H31N7O3/c1-4-22-27(37-21-8-6-7-19(17-21)29-23(35)5-2)32-26(24(31-22)25(28)36)30-18-9-11-20(12-10-18)34-15-13-33(3)14-16-34/h5-12,17H,2,4,13-16H2,1,3H3,(H2,28,36)(H,29,35)(H,30,32)	LVQGVZUDZSVRBM-UHFFFAOYSA-N	170461	US9085540, 1	Epidermal growth factor receptor	Homo sapiens		 1.3							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170461&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667534	312527235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314490	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)\C=C\CN(C)C)c1	InChI=1S/C30H38N8O3/c1-5-25-30(41-24-9-6-8-22(20-24)32-26(39)10-7-15-36(2)3)35-29(27(34-25)28(31)40)33-21-11-13-23(14-12-21)38-18-16-37(4)17-19-38/h6-14,20H,5,15-19H2,1-4H3,(H2,31,40)(H,32,39)(H,33,35)	HIBWFBVIUFIIAN-UHFFFAOYSA-N	170463	US9085540, 3	Epidermal growth factor receptor	Homo sapiens		 1.4							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170463&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667533	312527236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314491	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1C	InChI=1S/C28H33N7O3/c1-5-21-28(38-23-9-7-8-22(18(23)3)31-24(36)6-2)33-27(25(32-21)26(29)37)30-19-10-12-20(13-11-19)35-16-14-34(4)15-17-35/h6-13H,2,5,14-17H2,1,3-4H3,(H2,29,37)(H,30,33)(H,31,36)	AEBNZKWTLCUZBW-UHFFFAOYSA-N	170475	US9085540, 15	Epidermal growth factor receptor	Homo sapiens		 1.2							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170475&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667535	312527237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314492	CC(C)c1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C28H33N7O3/c1-5-23(36)30-20-7-6-8-22(17-20)38-28-24(18(2)3)32-25(26(29)37)27(33-28)31-19-9-11-21(12-10-19)35-15-13-34(4)14-16-35/h5-12,17-18H,1,13-16H2,2-4H3,(H2,29,37)(H,30,36)(H,31,33)	NXOMUJIORBFHSR-UHFFFAOYSA-N	170482	US9085540, 22	Epidermal growth factor receptor	Homo sapiens		 1.5							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170482&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667536	312527238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314493	CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(C)c2)nc1C1CCN(CC1)C(=O)C=C	InChI=1S/C32H46N8O2/c1-5-26-29(23-9-13-40(14-10-23)28(41)6-2)36-32(30(35-26)31(33)42)34-24-7-8-27(22(3)21-24)39-15-11-25(12-16-39)38-19-17-37(4)18-20-38/h6-8,21,23,25H,2,5,9-20H2,1,3-4H3,(H2,33,42)(H,34,36)	OVIJPRKXAGWPIR-UHFFFAOYSA-N	170484	US9085540, 24	Epidermal growth factor receptor	Homo sapiens		 1.1							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170484&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667664	312527239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314494	CN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)cnc2C(N)=O)cc1	InChI=1S/C25H27N7O3/c1-3-21(33)28-18-5-4-6-20(15-18)35-22-16-27-23(24(26)34)25(30-22)29-17-7-9-19(10-8-17)32-13-11-31(2)12-14-32/h3-10,15-16H,1,11-14H2,2H3,(H2,26,34)(H,28,33)(H,29,30)	YGIBTSMHVRPSJH-UHFFFAOYSA-N	170486	US9085540, 26	Epidermal growth factor receptor	Homo sapiens		 1.1							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170486&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667665	312527240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314495	CCc1nc(C(N)=O)c(Nc2ccc(OC)c(c2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C28H33N7O4/c1-5-21-28(39-20-9-7-8-18(16-20)30-24(36)6-2)33-27(25(32-21)26(29)37)31-19-10-11-23(38-4)22(17-19)35-14-12-34(3)13-15-35/h6-11,16-17H,2,5,12-15H2,1,3-4H3,(H2,29,37)(H,30,36)(H,31,33)	DLYLXKIKTZVXLV-UHFFFAOYSA-N	170502	US9085540, 42	Epidermal growth factor receptor	Homo sapiens		 1.2							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170502&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667666	312527241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314496	CCN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)c(CC)nc2C(N)=O)cc1	InChI=1S/C28H33N7O3/c1-4-23-28(38-22-9-7-8-20(18-22)30-24(36)5-2)33-27(25(32-23)26(29)37)31-19-10-12-21(13-11-19)35-16-14-34(6-3)15-17-35/h5,7-13,18H,2,4,6,14-17H2,1,3H3,(H2,29,37)(H,30,36)(H,31,33)	BLVSTWDZDHSEQQ-UHFFFAOYSA-N	170503	US9085540, 43	Epidermal growth factor receptor	Homo sapiens		 1.4							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170503&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667667	312527242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314497	CCc1c(nc(c(n1)C(=O)N)Nc2ccc(cc2)N3CCC(CC3)N4CCN(CC4)C)O[C@@H]5CCN(C5)C(=O)C=C	InChI=1S/C30H42N8O3/c1-4-25-30(41-24-12-15-38(20-24)26(39)5-2)34-29(27(33-25)28(31)40)32-21-6-8-22(9-7-21)36-13-10-23(11-14-36)37-18-16-35(3)17-19-37/h5-9,23-24H,2,4,10-20H2,1,3H3,(H2,31,40)(H,32,34)	QKDCLUARMDUUKN-UHFFFAOYSA-N	170514	US9085540, 54	Epidermal growth factor receptor	Homo sapiens		 1.7							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170514&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8RC	7LG8,5Y9T	71667668	312527243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314498	CC(C)c1nc(C(N)=O)c(Nc2cnn(c2)C2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C26H32N8O3/c1-5-21(35)29-17-7-6-8-20(13-17)37-26-22(16(2)3)31-23(24(27)36)25(32-26)30-18-14-28-34(15-18)19-9-11-33(4)12-10-19/h5-8,13-16,19H,1,9-12H2,2-4H3,(H2,27,36)(H,29,35)(H,30,32)	GWYBVGHLDQLEPN-UHFFFAOYSA-N	170516	US9085540, 56	Epidermal growth factor receptor	Homo sapiens		 1.3							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170516&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667814	312527244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314499	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)[C@@H](C)C2)nc1Oc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C28H33N7O3/c1-5-23-28(38-22-9-7-8-20(16-22)30-24(36)6-2)33-27(25(32-23)26(29)37)31-19-10-12-21(13-11-19)35-15-14-34(4)18(3)17-35/h6-13,16,18H,2,5,14-15,17H2,1,3-4H3,(H2,29,37)(H,30,36)(H,31,33)	VIKYVWOFKQNEHB-UHFFFAOYSA-N	170523	US9085540, 63	Epidermal growth factor receptor	Homo sapiens		 1.8							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170523&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667815	312527245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314500	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)[C@H](C)C2)nc1Oc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C28H33N7O3/c1-5-23-28(38-22-9-7-8-20(16-22)30-24(36)6-2)33-27(25(32-23)26(29)37)31-19-10-12-21(13-11-19)35-15-14-34(4)18(3)17-35/h6-13,16,18H,2,5,14-15,17H2,1,3-4H3,(H2,29,37)(H,30,36)(H,31,33)	VIKYVWOFKQNEHB-UHFFFAOYSA-N	170524	US9085540, 64	Epidermal growth factor receptor	Homo sapiens		 1.7							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170524&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667816	312527246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314501	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1C1CCN(CC1)C(=O)C=C	InChI=1S/C31H44N8O2/c1-4-26-28(22-10-14-39(15-11-22)27(40)5-2)35-31(29(34-26)30(32)41)33-23-6-8-24(9-7-23)37-16-12-25(13-17-37)38-20-18-36(3)19-21-38/h5-9,22,25H,2,4,10-21H2,1,3H3,(H2,32,41)(H,33,35)	ZBFUCVHDBVLZOQ-UHFFFAOYSA-N	170529	US9085540, 69	Epidermal growth factor receptor	Homo sapiens		 1.3							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170529&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667817	312527247							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314502	CCC(=O)N1CC[C@H](C1)Oc1nc(Nc2ccc(cc2)N2CCN(C)CC2)c(nc1CC)C(N)=O |r|	InChI=1S/C25H35N7O3/c1-4-20-25(35-19-10-11-32(16-19)21(33)5-2)29-24(22(28-20)23(26)34)27-17-6-8-18(9-7-17)31-14-12-30(3)13-15-31/h6-9,19H,4-5,10-16H2,1-3H3,(H2,26,34)(H,27,29)	NHPBMYSFPQSLCG-UHFFFAOYSA-N	170533	US9085540, 73	Epidermal growth factor receptor	Homo sapiens		 1.2							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117675851	312527248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314503	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1O[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C31H44N8O3/c1-4-26-31(42-25-7-6-14-39(21-25)27(40)5-2)35-30(28(34-26)29(32)41)33-22-8-10-23(11-9-22)37-15-12-24(13-16-37)38-19-17-36(3)18-20-38/h5,8-11,24-25H,2,4,6-7,12-21H2,1,3H3,(H2,32,41)(H,33,35)	JSVPZRBHIKMSLF-UHFFFAOYSA-N	170539	US9085540, 79	Epidermal growth factor receptor	Homo sapiens		 1.3							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667975	312527249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314504	CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(C)c2)nc1O[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C32H46N8O3/c1-5-26-32(43-25-8-7-13-40(21-25)28(41)6-2)36-31(29(35-26)30(33)42)34-23-9-10-27(22(3)20-23)39-14-11-24(12-15-39)38-18-16-37(4)17-19-38/h6,9-10,20,24-25H,2,5,7-8,11-19,21H2,1,3-4H3,(H2,33,42)(H,34,36)	IQUSBNFTZLAHTF-UHFFFAOYSA-N	170540	US9085540, 80	Epidermal growth factor receptor	Homo sapiens		 1.2							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667976	312527250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314505	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cc(NC(=O)C=C)ccc1F	InChI=1S/C27H30FN7O3/c1-4-21-27(38-22-16-18(8-11-20(22)28)30-23(36)5-2)33-26(24(32-21)25(29)37)31-17-6-9-19(10-7-17)35-14-12-34(3)13-15-35/h5-11,16H,2,4,12-15H2,1,3H3,(H2,29,37)(H,30,36)(H,31,33)	GNMULHTXVBBKDA-UHFFFAOYSA-N	170542	US9085540, 82	Epidermal growth factor receptor	Homo sapiens		 1.5							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667977	312527251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314506	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C27H31N7O3/c1-4-22-27(37-21-8-6-7-19(17-21)29-23(35)5-2)32-26(24(31-22)25(28)36)30-18-9-11-20(12-10-18)34-15-13-33(3)14-16-34/h5-12,17H,2,4,13-16H2,1,3H3,(H2,28,36)(H,29,35)(H,30,32)	LVQGVZUDZSVRBM-UHFFFAOYSA-N	170461	US9085540, 1	Epidermal growth factor receptor	Homo sapiens		 2.2							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170461&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667534	312527235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314507	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)\C=C\CN(C)C)c1	InChI=1S/C30H38N8O3/c1-5-25-30(41-24-9-6-8-22(20-24)32-26(39)10-7-15-36(2)3)35-29(27(34-25)28(31)40)33-21-11-13-23(14-12-21)38-18-16-37(4)17-19-38/h6-14,20H,5,15-19H2,1-4H3,(H2,31,40)(H,32,39)(H,33,35)	HIBWFBVIUFIIAN-UHFFFAOYSA-N	170463	US9085540, 3	Epidermal growth factor receptor	Homo sapiens		 17							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170463&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667533	312527236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314508	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1C	InChI=1S/C28H33N7O3/c1-5-21-28(38-23-9-7-8-22(18(23)3)31-24(36)6-2)33-27(25(32-21)26(29)37)30-19-10-12-20(13-11-19)35-16-14-34(4)15-17-35/h6-13H,2,5,14-17H2,1,3-4H3,(H2,29,37)(H,30,33)(H,31,36)	AEBNZKWTLCUZBW-UHFFFAOYSA-N	170475	US9085540, 15	Epidermal growth factor receptor	Homo sapiens		 1.1							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170475&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667535	312527237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314509	CC(C)c1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C28H33N7O3/c1-5-23(36)30-20-7-6-8-22(17-20)38-28-24(18(2)3)32-25(26(29)37)27(33-28)31-19-9-11-21(12-10-19)35-15-13-34(4)14-16-35/h5-12,17-18H,1,13-16H2,2-4H3,(H2,29,37)(H,30,36)(H,31,33)	NXOMUJIORBFHSR-UHFFFAOYSA-N	170482	US9085540, 22	Epidermal growth factor receptor	Homo sapiens		 1.9							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170482&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667536	312527238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314510	CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(C)c2)nc1C1CCN(CC1)C(=O)C=C	InChI=1S/C32H46N8O2/c1-5-26-29(23-9-13-40(14-10-23)28(41)6-2)36-32(30(35-26)31(33)42)34-24-7-8-27(22(3)21-24)39-15-11-25(12-16-39)38-19-17-37(4)18-20-38/h6-8,21,23,25H,2,5,9-20H2,1,3-4H3,(H2,33,42)(H,34,36)	OVIJPRKXAGWPIR-UHFFFAOYSA-N	170484	US9085540, 24	Epidermal growth factor receptor	Homo sapiens		 2.1							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170484&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667664	312527239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314511	CN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)cnc2C(N)=O)cc1	InChI=1S/C25H27N7O3/c1-3-21(33)28-18-5-4-6-20(15-18)35-22-16-27-23(24(26)34)25(30-22)29-17-7-9-19(10-8-17)32-13-11-31(2)12-14-32/h3-10,15-16H,1,11-14H2,2H3,(H2,26,34)(H,28,33)(H,29,30)	YGIBTSMHVRPSJH-UHFFFAOYSA-N	170486	US9085540, 26	Epidermal growth factor receptor	Homo sapiens		 0.92							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170486&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667665	312527240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314512	CCc1nc(C(N)=O)c(Nc2ccc(OC)c(c2)N2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C28H33N7O4/c1-5-21-28(39-20-9-7-8-18(16-20)30-24(36)6-2)33-27(25(32-21)26(29)37)31-19-10-11-23(38-4)22(17-19)35-14-12-34(3)13-15-35/h6-11,16-17H,2,5,12-15H2,1,3-4H3,(H2,29,37)(H,30,36)(H,31,33)	DLYLXKIKTZVXLV-UHFFFAOYSA-N	170502	US9085540, 42	Epidermal growth factor receptor	Homo sapiens		 1.4							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170502&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667666	312527241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314513	CCN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)c(CC)nc2C(N)=O)cc1	InChI=1S/C28H33N7O3/c1-4-23-28(38-22-9-7-8-20(18-22)30-24(36)5-2)33-27(25(32-23)26(29)37)31-19-10-12-21(13-11-19)35-16-14-34(6-3)15-17-35/h5,7-13,18H,2,4,6,14-17H2,1,3H3,(H2,29,37)(H,30,36)(H,31,33)	BLVSTWDZDHSEQQ-UHFFFAOYSA-N	170503	US9085540, 43	Epidermal growth factor receptor	Homo sapiens		 0.66							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170503&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667667	312527242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314514	CCc1c(nc(c(n1)C(=O)N)Nc2ccc(cc2)N3CCC(CC3)N4CCN(CC4)C)O[C@@H]5CCN(C5)C(=O)C=C	InChI=1S/C30H42N8O3/c1-4-25-30(41-24-12-15-38(20-24)26(39)5-2)34-29(27(33-25)28(31)40)32-21-6-8-22(9-7-21)36-13-10-23(11-14-36)37-18-16-35(3)17-19-37/h5-9,23-24H,2,4,10-20H2,1,3H3,(H2,31,40)(H,32,34)	QKDCLUARMDUUKN-UHFFFAOYSA-N	170514	US9085540, 54	Epidermal growth factor receptor	Homo sapiens		 4.5							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170514&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8RC	7LG8,5Y9T	71667668	312527243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314515	CC(C)c1nc(C(N)=O)c(Nc2cnn(c2)C2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C26H32N8O3/c1-5-21(35)29-17-7-6-8-20(13-17)37-26-22(16(2)3)31-23(24(27)36)25(32-26)30-18-14-28-34(15-18)19-9-11-33(4)12-10-19/h5-8,13-16,19H,1,9-12H2,2-4H3,(H2,27,36)(H,29,35)(H,30,32)	GWYBVGHLDQLEPN-UHFFFAOYSA-N	170516	US9085540, 56	Epidermal growth factor receptor	Homo sapiens		 2							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170516&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667814	312527244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314516	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)[C@@H](C)C2)nc1Oc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C28H33N7O3/c1-5-23-28(38-22-9-7-8-20(16-22)30-24(36)6-2)33-27(25(32-23)26(29)37)31-19-10-12-21(13-11-19)35-15-14-34(4)18(3)17-35/h6-13,16,18H,2,5,14-15,17H2,1,3-4H3,(H2,29,37)(H,30,36)(H,31,33)	VIKYVWOFKQNEHB-UHFFFAOYSA-N	170523	US9085540, 63	Epidermal growth factor receptor	Homo sapiens		 1.2							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170523&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667815	312527245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314517	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)[C@H](C)C2)nc1Oc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C28H33N7O3/c1-5-23-28(38-22-9-7-8-20(16-22)30-24(36)6-2)33-27(25(32-23)26(29)37)31-19-10-12-21(13-11-19)35-15-14-34(4)18(3)17-35/h6-13,16,18H,2,5,14-15,17H2,1,3-4H3,(H2,29,37)(H,30,36)(H,31,33)	VIKYVWOFKQNEHB-UHFFFAOYSA-N	170524	US9085540, 64	Epidermal growth factor receptor	Homo sapiens		 0.56							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170524&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667816	312527246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314518	CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1C1CCN(CC1)C(=O)C=C	InChI=1S/C31H44N8O2/c1-4-26-28(22-10-14-39(15-11-22)27(40)5-2)35-31(29(34-26)30(32)41)33-23-6-8-24(9-7-23)37-16-12-25(13-17-37)38-20-18-36(3)19-21-38/h5-9,22,25H,2,4,10-21H2,1,3H3,(H2,32,41)(H,33,35)	ZBFUCVHDBVLZOQ-UHFFFAOYSA-N	170529	US9085540, 69	Epidermal growth factor receptor	Homo sapiens		 4							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170529&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71667817	312527247							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
314519	CCC(=O)N1CC[C@H](C1)Oc1nc(Nc2ccc(cc2)N2CCN(C)CC2)c(nc1CC)C(N)=O |r|	InChI=1S/C25H35N7O3/c1-4-20-25(35-19-10-11-32(16-19)21(33)5-2)29-24(22(28-20)23(26)34)27-17-6-8-18(9-7-17)31-14-12-30(3)13-15-31/h6-9,19H,4-5,10-16H2,1-3H3,(H2,26,34)(H,27,29)	NHPBMYSFPQSLCG-UHFFFAOYSA-N	170533	US9085540, 73	Epidermal growth factor receptor	Homo sapiens		 5.6							US Patent		10.7270/Q2154FSV		aid1801434	US9085540	Matsuya, T; Kondoh, Y; Shimada, I; Kikuchi, S; Iida, M; Onda, K; Fukudome, H; Takemoto, Y; Shindou, N; Sakagami, H; Hamaguchi, H	7/21/2015	3/14/2016	Astellas Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=170533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=170533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117675851	312527248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318691	CC(C)n5c(Nc1ccccc1)nc4cnc(Nc3ccc(C(=O)NN2CCN(C)CC2)cc3)nc45	InChI=1S/C26H31N9O/c1-18(2)35-23-22(30-26(35)29-20-7-5-4-6-8-20)17-27-25(31-23)28-21-11-9-19(10-12-21)24(36)32-34-15-13-33(3)14-16-34/h4-12,17-18H,13-16H2,1-3H3,(H,29,30)(H,32,36)(H,27,28,31)	XPVKDEYRNJRERS-UHFFFAOYSA-N	173427	US9096601, 8-1	Epidermal growth factor receptor	Homo sapiens		 3							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122196914	312697338							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318692	CC(C)n1c(Nc2ccc(F)c(Cl)c2)nc2cnc(Nc3ccc(cc3)C(=O)NN3CCN(C)CC3)nc12	InChI=1S/C26H29ClFN9O/c1-16(2)37-23-22(32-26(37)31-19-8-9-21(28)20(27)14-19)15-29-25(33-23)30-18-6-4-17(5-7-18)24(38)34-36-12-10-35(3)11-13-36/h4-9,14-16H,10-13H2,1-3H3,(H,31,32)(H,34,38)(H,29,30,33)	LSNFUHFMDCZXMM-UHFFFAOYSA-N	173428	US9096601, 8-2	Epidermal growth factor receptor	Homo sapiens		 2							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759464	312697339							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318693	CC(=O)Nc5cccc(Nc4nc3cnc(Nc2ccc(C(=O)NN1CCN(C)CC1)cc2F)nc3n4C(C)C)c5	InChI=1S/C28H33FN10O2/c1-17(2)39-25-24(34-28(39)32-21-7-5-6-20(15-21)31-18(3)40)16-30-27(35-25)33-23-9-8-19(14-22(23)29)26(41)36-38-12-10-37(4)11-13-38/h5-9,14-17H,10-13H2,1-4H3,(H,31,40)(H,32,34)(H,36,41)(H,30,33,35)	ABJQOAJWHXIMAK-UHFFFAOYSA-N	173429	US9096601, 8-3	Epidermal growth factor receptor	Homo sapiens		 25							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122196915	312697340							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318694	CC(C)n1c(Nc2ccccc2)nc2cnc(Nc3ccc(cc3F)C(=O)NN3CCN(C)CC3)nc12	InChI=1S/C26H30FN9O/c1-17(2)36-23-22(31-26(36)29-19-7-5-4-6-8-19)16-28-25(32-23)30-21-10-9-18(15-20(21)27)24(37)33-35-13-11-34(3)12-14-35/h4-10,15-17H,11-14H2,1-3H3,(H,29,31)(H,33,37)(H,28,30,32)	NVOZOBFMWRZFHB-UHFFFAOYSA-N	173430	US9096601, 8-6::US9096601, 8-4	Epidermal growth factor receptor	Homo sapiens		 30							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759463	312697341							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318695	CC(C)n1c(Nc2ccc(F)c(Cl)c2)nc2cnc(Nc3ccc(cc3F)C(=O)NN3CCN(C)CC3)nc12	InChI=1S/C26H28ClF2N9O/c1-15(2)38-23-22(33-26(38)31-17-5-6-19(28)18(27)13-17)14-30-25(34-23)32-21-7-4-16(12-20(21)29)24(39)35-37-10-8-36(3)9-11-37/h4-7,12-15H,8-11H2,1-3H3,(H,31,33)(H,35,39)(H,30,32,34)	BMNRVDRIGUMQRP-UHFFFAOYSA-N	173431	US9096601, 8-5	Epidermal growth factor receptor	Homo sapiens		 4							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759657	312697342							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318696	CC(C)n1c(Nc2ccccc2)nc2cnc(Nc3ccc(cc3F)C(=O)NN3CCN(C)CC3)nc12	InChI=1S/C26H30FN9O/c1-17(2)36-23-22(31-26(36)29-19-7-5-4-6-8-19)16-28-25(32-23)30-21-10-9-18(15-20(21)27)24(37)33-35-13-11-34(3)12-14-35/h4-10,15-17H,11-14H2,1-3H3,(H,29,31)(H,33,37)(H,28,30,32)	NVOZOBFMWRZFHB-UHFFFAOYSA-N	173430	US9096601, 8-6::US9096601, 8-4	Epidermal growth factor receptor	Homo sapiens		 1							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759463	312697341							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318697	COc1cc(ccc1Nc1ncc2nc(Nc3ccccc3)n(C(C)C)c2n1)C(=O)NN1CCN(C)CC1	InChI=1S/C27H33N9O2/c1-18(2)36-24-22(31-27(36)29-20-8-6-5-7-9-20)17-28-26(32-24)30-21-11-10-19(16-23(21)38-4)25(37)33-35-14-12-34(3)13-15-35/h5-11,16-18H,12-15H2,1-4H3,(H,29,31)(H,33,37)(H,28,30,32)	RCODRVRIPGNRTG-UHFFFAOYSA-N	173433	US9096601, 8-7	Epidermal growth factor receptor	Homo sapiens		 7							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759659	312697343							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318698	CC(C)n1c(Nc2ccccc2)nc2cnc(Nc3ccc(cc3)C(=O)NC3CCN(C)CC3)nc12	InChI=1S/C27H32N8O/c1-18(2)35-24-23(32-27(35)31-20-7-5-4-6-8-20)17-28-26(33-24)30-21-11-9-19(10-12-21)25(36)29-22-13-15-34(3)16-14-22/h4-12,17-18,22H,13-16H2,1-3H3,(H,29,36)(H,31,32)(H,28,30,33)	FXJYGGNAOIGUCL-UHFFFAOYSA-N	173435	US9096601, 8-9	Epidermal growth factor receptor	Homo sapiens		 1							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759840	312697344							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318699	CC(C)n1c2c(cnc(n2)Nc3ccc(cc3)N4CCN(CC4)C)nc1Nc5ccccc5	InChI=1S/C25H30N8/c1-18(2)33-23-22(29-25(33)28-19-7-5-4-6-8-19)17-26-24(30-23)27-20-9-11-21(12-10-20)32-15-13-31(3)14-16-32/h4-12,17-18H,13-16H2,1-3H3,(H,28,29)(H,26,27,30)	BJQHKZQCLPRNHN-UHFFFAOYSA-N	173436	US9096601, 8-10	Epidermal growth factor receptor	Homo sapiens		 5							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	7XO	5X26,5X2A	54759842	312697345							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318700	CC(C)n1c(Nc2cccc(Br)c2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C25H29BrN8/c1-17(2)34-23-22(30-25(34)29-20-6-4-5-18(26)15-20)16-27-24(31-23)28-19-7-9-21(10-8-19)33-13-11-32(3)12-14-33/h4-10,15-17H,11-14H2,1-3H3,(H,29,30)(H,27,28,31)	NYBSAZXOBAFBSJ-UHFFFAOYSA-N	173437	US9096601, 8-11	Epidermal growth factor receptor	Homo sapiens		 7							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759841	312697346							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318701	CC(C)n1c(Nc2cccc(c2)C#C)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C27H30N8/c1-5-20-7-6-8-22(17-20)30-27-31-24-18-28-26(32-25(24)35(27)19(2)3)29-21-9-11-23(12-10-21)34-15-13-33(4)14-16-34/h1,6-12,17-19H,13-16H2,2-4H3,(H,30,31)(H,28,29,32)	UHUCLHAHTSRPSQ-UHFFFAOYSA-N	173438	US9096601, 8-12	Epidermal growth factor receptor	Homo sapiens		 4							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759843	312697347							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318702	CC(C)n1c(Nc2ccc(F)c(Cl)c2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C25H28ClFN8/c1-16(2)35-23-22(31-25(35)30-18-6-9-21(27)20(26)14-18)15-28-24(32-23)29-17-4-7-19(8-5-17)34-12-10-33(3)11-13-34/h4-9,14-16H,10-13H2,1-3H3,(H,30,31)(H,28,29,32)	DACSXLTVEKOFCW-UHFFFAOYSA-N	173439	US9096601, 8-13	Epidermal growth factor receptor	Homo sapiens		 4							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173439&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54759844	312697348							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318703	CC(C)n1c(Nc2ccc(Br)cc2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C25H29BrN8/c1-17(2)34-23-22(30-25(34)29-20-6-4-18(26)5-7-20)16-27-24(31-23)28-19-8-10-21(11-9-19)33-14-12-32(3)13-15-33/h4-11,16-17H,12-15H2,1-3H3,(H,29,30)(H,27,28,31)	YLRQTRNCNYEOFF-UHFFFAOYSA-N	173441	US9096601, 8-15	Epidermal growth factor receptor	Homo sapiens		 3							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70647974	312697349							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318704	CC(C)n1c(Nc2cccc(c2)C(F)(F)F)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C26H29F3N8/c1-17(2)37-23-22(33-25(37)32-20-6-4-5-18(15-20)26(27,28)29)16-30-24(34-23)31-19-7-9-21(10-8-19)36-13-11-35(3)12-14-36/h4-10,15-17H,11-14H2,1-3H3,(H,32,33)(H,30,31,34)	WBIXSULLIITHLG-UHFFFAOYSA-N	173442	US9096601, 8-16	Epidermal growth factor receptor	Homo sapiens		 3							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173442&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760027	312697350							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318705	COc1cccc(Nc2nc3cnc(Nc4ccc(cc4)N4CCN(C)CC4)nc3n2C(C)C)c1	InChI=1S/C26H32N8O/c1-18(2)34-24-23(30-26(34)29-20-6-5-7-22(16-20)35-4)17-27-25(31-24)28-19-8-10-21(11-9-19)33-14-12-32(3)13-15-33/h5-11,16-18H,12-15H2,1-4H3,(H,29,30)(H,27,28,31)	RPHNDUBGTOJBFI-UHFFFAOYSA-N	173443	US9096601, 8-17	Epidermal growth factor receptor	Homo sapiens		 4							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760028	312697351							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318706	COc1ccc(Nc2nc3cnc(Nc4ccc(cc4)N4CCN(C)CC4)nc3n2C(C)C)cc1	InChI=1S/C26H32N8O/c1-18(2)34-24-23(30-26(34)29-20-7-11-22(35-4)12-8-20)17-27-25(31-24)28-19-5-9-21(10-6-19)33-15-13-32(3)14-16-33/h5-12,17-18H,13-16H2,1-4H3,(H,29,30)(H,27,28,31)	VHHKVHHSKBHBAO-UHFFFAOYSA-N	173444	US9096601, 8-18	Epidermal growth factor receptor	Homo sapiens		 30							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760029	312697352							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318707	CC(C)n1c(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C32H34ClFN8O/c1-21(2)42-30-28(19-35-31(39-30)36-24-7-10-26(11-8-24)41-15-13-40(3)14-16-41)38-32(42)37-25-9-12-29(27(33)18-25)43-20-22-5-4-6-23(34)17-22/h4-12,17-19,21H,13-16,20H2,1-3H3,(H,37,38)(H,35,36,39)	VSRRLIKKZGFAMN-UHFFFAOYSA-N	173445	US9096601, 8-19	Epidermal growth factor receptor	Homo sapiens		 5							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760030	312697353							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318708	CC(C)n1c(Nc2ccc(NC(=O)Nc3ccc(F)c(Cl)c3)cc2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C32H34ClFN10O/c1-20(2)44-29-28(19-35-30(41-29)36-21-8-11-25(12-9-21)43-16-14-42(3)15-17-43)40-31(44)37-22-4-6-23(7-5-22)38-32(45)39-24-10-13-27(34)26(33)18-24/h4-13,18-20H,14-17H2,1-3H3,(H,37,40)(H,35,36,41)(H2,38,39,45)	OAZZXYMTTQCAGN-UHFFFAOYSA-N	173447	US9096601, 8-21	Epidermal growth factor receptor	Homo sapiens		 11							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760200	312697354							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318709	CC(C)n1c(Nc2ccc(cc2)C(=O)Nc2cccc(F)c2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C32H34FN9O/c1-21(2)42-29-28(20-34-31(39-29)36-24-11-13-27(14-12-24)41-17-15-40(3)16-18-41)38-32(42)37-25-9-7-22(8-10-25)30(43)35-26-6-4-5-23(33)19-26/h4-14,19-21H,15-18H2,1-3H3,(H,35,43)(H,37,38)(H,34,36,39)	IKULNRLYMKMRGA-UHFFFAOYSA-N	173448	US9096601, 8-22	Epidermal growth factor receptor	Homo sapiens		 117							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760201	312697355							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318710	CN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)n(C4CC4)c3n2)cc1	InChI=1S/C25H28N8/c1-31-13-15-32(16-14-31)20-9-7-19(8-10-20)27-24-26-17-22-23(30-24)33(21-11-12-21)25(29-22)28-18-5-3-2-4-6-18/h2-10,17,21H,11-16H2,1H3,(H,28,29)(H,26,27,30)	WABPITVYBFPGOY-UHFFFAOYSA-N	173449	US9096601, 8-23	Epidermal growth factor receptor	Homo sapiens		 7							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760202	312697356							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318711	CN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)n(C)c3n2)cc1	InChI=1S/C23H26N8/c1-29-12-14-31(15-13-29)19-10-8-18(9-11-19)25-22-24-16-20-21(28-22)30(2)23(27-20)26-17-6-4-3-5-7-17/h3-11,16H,12-15H2,1-2H3,(H,26,27)(H,24,25,28)	ZZSYRUGQSJWOAC-UHFFFAOYSA-N	173450	US9096601, 8-24	Epidermal growth factor receptor	Homo sapiens		 12							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173450&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760203	312697357							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318712	CN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)[nH]c3n2)cc1	InChI=1S/C22H24N8/c1-29-11-13-30(14-12-29)18-9-7-17(8-10-18)24-21-23-15-19-20(27-21)28-22(26-19)25-16-5-3-2-4-6-16/h2-10,15H,11-14H2,1H3,(H3,23,24,25,26,27,28)	FKSOXOHTTFKOQL-UHFFFAOYSA-N	173451	US9096601, 8-25	Epidermal growth factor receptor	Homo sapiens		 29							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173451&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760382	312697358							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318713	CN1CCN(CC1)c2ccc(cc2)Nc3ncc4c(n3)n(c(n4)Nc5ccccc5)C6CCCC6	InChI=1S/C27H32N8/c1-33-15-17-34(18-16-33)22-13-11-21(12-14-22)29-26-28-19-24-25(32-26)35(23-9-5-6-10-23)27(31-24)30-20-7-3-2-4-8-20/h2-4,7-8,11-14,19,23H,5-6,9-10,15-18H2,1H3,(H,30,31)(H,28,29,32)	QPOURHROVVCOHC-UHFFFAOYSA-N	50399676	CHEMBL2178352::US9096601, 8-26	Epidermal growth factor receptor	Homo sapiens		 1							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399676&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	7XR	5X2C,5X27	54760383	163348700		CHEMBL2178352					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318714	CC(C)n1c(Nc2ccc(cc2)C(F)(F)F)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C26H29F3N8/c1-17(2)37-23-22(33-25(37)32-20-6-4-18(5-7-20)26(27,28)29)16-30-24(34-23)31-19-8-10-21(11-9-19)36-14-12-35(3)13-15-36/h4-11,16-17H,12-15H2,1-3H3,(H,32,33)(H,30,31,34)	FSMLLEGNJUYKOD-UHFFFAOYSA-N	173452	US9096601, 8-27	Epidermal growth factor receptor	Homo sapiens		 34							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173452&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760384	312697359							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318715	CC(C)n1c(Nc2cccnc2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C24H29N9/c1-17(2)33-22-21(29-24(33)28-19-5-4-10-25-15-19)16-26-23(30-22)27-18-6-8-20(9-7-18)32-13-11-31(3)12-14-32/h4-10,15-17H,11-14H2,1-3H3,(H,28,29)(H,26,27,30)	WSOHOUHPUOAXIN-UHFFFAOYSA-N	173454	US9096601, 8-29	Epidermal growth factor receptor	Homo sapiens		 31							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173454&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760385	312697360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318716	CC(C)n1c(NC2CCCCC2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12	InChI=1S/C25H36N8/c1-18(2)33-23-22(29-25(33)28-19-7-5-4-6-8-19)17-26-24(30-23)27-20-9-11-21(12-10-20)32-15-13-31(3)14-16-32/h9-12,17-19H,4-8,13-16H2,1-3H3,(H,28,29)(H,26,27,30)	IDRLVNWZKKHTGY-UHFFFAOYSA-N	173455	US9096601, 8-30	Epidermal growth factor receptor	Homo sapiens		 15							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173455&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760577	312697361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
318717	CC(C)n1c(Nc2ccccc2)nc2cnc(Nc3cccc(NC(=O)C=C)c3)nc12	InChI=1S/C23H23N7O/c1-4-20(31)25-17-11-8-12-18(13-17)26-22-24-14-19-21(29-22)30(15(2)3)23(28-19)27-16-9-6-5-7-10-16/h4-15H,1H2,2-3H3,(H,25,31)(H,27,28)(H,24,26,29)	KJFSEEWSSQIOAL-UHFFFAOYSA-N	173463	US9096601, 8-38	Epidermal growth factor receptor	Homo sapiens		 2							US Patent		10.7270/Q2NS0SNG		aid1801474	US9096601	Yang, S; Wei, Y	8/4/2015	3/28/2016	Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=173463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=173463&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54760773	312697362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
327971	Cc1nn(-c2ccccc2)c2nc(C)cc(OCC(=O)N\N=C\c3ccc(O)cc3)c12	InChI=1S/C23H21N5O3/c1-15-12-20(31-14-21(30)26-24-13-17-8-10-19(29)11-9-17)22-16(2)27-28(23(22)25-15)18-6-4-3-5-7-18/h3-13,29H,14H2,1-2H3,(H,26,30)	ALTUINAZDKCEFE-UHFFFAOYSA-N	181095	N-(4-Hydroxybenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl-oxy)acetohydrazide (12a)	Epidermal growth factor receptor	Homo sapiens		 1.050e+4							Curated from the literature by BindingDB	10.1016/j.bioorg.2016.03.011	10.7270/Q2VQ31GF	27043178	aid1801647		Abdelgawad, MA; Bakr, RB; Alkhoja, OA; Mohamed, WR	6/28/2016	5/26/2016	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=181095	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=181095&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			119081284	313389142							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
327972	Cc1nn(-c2ccccc2)c2nc(C)cc(OCC(=O)N\N=C\c3ccc(F)cc3)c12	InChI=1S/C23H20FN5O2/c1-15-12-20(31-14-21(30)27-25-13-17-8-10-18(24)11-9-17)22-16(2)28-29(23(22)26-15)19-6-4-3-5-7-19/h3-13H,14H2,1-2H3,(H,27,30)	RGOKSDDGCXEJFD-UHFFFAOYSA-N	181096	N-(4-fluorobenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)acetohydrazide (12b)	Epidermal growth factor receptor	Homo sapiens		 3.002e+4							Curated from the literature by BindingDB	10.1016/j.bioorg.2016.03.011	10.7270/Q2VQ31GF	27043178	aid1801647		Abdelgawad, MA; Bakr, RB; Alkhoja, OA; Mohamed, WR	6/28/2016	5/26/2016	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=181096	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=181096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			119081285	313389143							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
327973	COc1ccc(\C=N\NC(=O)COc2cc(C)nc3n(nc(C)c23)-c2ccccc2)cc1	InChI=1S/C24H23N5O3/c1-16-13-21(23-17(2)28-29(24(23)26-16)19-7-5-4-6-8-19)32-15-22(30)27-25-14-18-9-11-20(31-3)12-10-18/h4-14H,15H2,1-3H3,(H,27,30)	VSFKWJSAWPSEMX-UHFFFAOYSA-N	181097	N-(4-methoxybenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)acetohydrazide (12c)	Epidermal growth factor receptor	Homo sapiens		 4.72e+3							Curated from the literature by BindingDB	10.1016/j.bioorg.2016.03.011	10.7270/Q2VQ31GF	27043178	aid1801647		Abdelgawad, MA; Bakr, RB; Alkhoja, OA; Mohamed, WR	6/28/2016	5/26/2016	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=181097	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=181097&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			119081286	313389144							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
327974	Cc1nn(-c2ccccc2)c2nc(C)cc(OCC(=O)N\N=C\c3ccc(Cl)cc3)c12	InChI=1S/C23H20ClN5O2/c1-15-12-20(31-14-21(30)27-25-13-17-8-10-18(24)11-9-17)22-16(2)28-29(23(22)26-15)19-6-4-3-5-7-19/h3-13H,14H2,1-2H3,(H,27,30)	BUXZATISTDMNKH-UHFFFAOYSA-N	181098	N-(4-chlorobenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)acetohydrazide (12d)	Epidermal growth factor receptor	Homo sapiens		 5.01e+3							Curated from the literature by BindingDB	10.1016/j.bioorg.2016.03.011	10.7270/Q2VQ31GF	27043178	aid1801647		Abdelgawad, MA; Bakr, RB; Alkhoja, OA; Mohamed, WR	6/28/2016	5/26/2016	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=181098	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=181098&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			119081287	313389145							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
327975	Cc1nn(-c2ccccc2)c2nc(C)cc(OCC(=O)N\N=C\c3ccc(cc3)[N+]([O-])=O)c12	InChI=1S/C23H20N6O4/c1-15-12-20(22-16(2)27-28(23(22)25-15)18-6-4-3-5-7-18)33-14-21(30)26-24-13-17-8-10-19(11-9-17)29(31)32/h3-13H,14H2,1-2H3,(H,26,30)	WTDFEKPJLXZHRM-UHFFFAOYSA-N	181099	N-(4-chlorobenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)acetohydrazide (12e)	Epidermal growth factor receptor	Homo sapiens		 1.149e+4							Curated from the literature by BindingDB	10.1016/j.bioorg.2016.03.011	10.7270/Q2VQ31GF	27043178	aid1801647		Abdelgawad, MA; Bakr, RB; Alkhoja, OA; Mohamed, WR	6/28/2016	5/26/2016	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=181099	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=181099&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			119081288	313389146							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
327976	Cc1nn(-c2ccccc2)c2nc(C)cc(OCC(=O)N\N=C\c3ccc(cc3)C(F)(F)F)c12	InChI=1S/C24H20F3N5O2/c1-15-12-20(22-16(2)31-32(23(22)29-15)19-6-4-3-5-7-19)34-14-21(33)30-28-13-17-8-10-18(11-9-17)24(25,26)27/h3-13H,14H2,1-2H3,(H,30,33)	NLPLBZBEQOPVHV-UHFFFAOYSA-N	181100	N-(4-Trifluoromethylbenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)acetohydrazide (12f)	Epidermal growth factor receptor	Homo sapiens		 3.588e+4							Curated from the literature by BindingDB	10.1016/j.bioorg.2016.03.011	10.7270/Q2VQ31GF	27043178	aid1801647		Abdelgawad, MA; Bakr, RB; Alkhoja, OA; Mohamed, WR	6/28/2016	5/26/2016	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=181100	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=181100&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			119081289	313389147							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
327977	COc1cc(\C=N\NC(=O)COc2cc(C)nc3n(nc(C)c23)-c2ccccc2)cc(OC)c1OC	InChI=1S/C26H27N5O5/c1-16-11-20(24-17(2)30-31(26(24)28-16)19-9-7-6-8-10-19)36-15-23(32)29-27-14-18-12-21(33-3)25(35-5)22(13-18)34-4/h6-14H,15H2,1-5H3,(H,29,32)	BYWFIBRCZKTKIW-UHFFFAOYSA-N	181101	N-(3,4,5-trimethoxybenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)acetohydrazide (12g)	Epidermal growth factor receptor	Homo sapiens		 4.18e+3							Curated from the literature by BindingDB	10.1016/j.bioorg.2016.03.011	10.7270/Q2VQ31GF	27043178	aid1801647		Abdelgawad, MA; Bakr, RB; Alkhoja, OA; Mohamed, WR	6/28/2016	5/26/2016	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=181101	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=181101&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			119081290	313389148							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342605	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)	XYFPWWZEPKGCCK-UHFFFAOYSA-N	50357312	IBRUTINIB::US9181263, 1::US9108973, Ref 1::US9278100, 1::US10124003, Ref. Ex. Compound 1::PCI-32765::US10711006, Compound Ibrutinib::US10919899, Ibrutinib::US10835536, Ref. Ex. Comp 1::US10793575, Example ibrutinib::US11186578, Example Ibrutinib::US11078206, Example Ibrutinib::US11407754, Example Ibrutinib::US11339167, Example Ibrutinib::US20230364079, Example Ibrutinib::US20240059694, Compound Ibrutinib::US20240139326, Compound Ibrutinib::US20240358707, Compound 13	Epidermal growth factor receptor	Homo sapiens		 0.5							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821094	136961336			DB09053				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342626	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C |r,wU:23			97672	US8476284, 40::US9133201, 10::US9181263, 9::US9278100, 9::US20240317756, Compound 9::US20240358707, Compound 10	Epidermal growth factor receptor	Homo sapiens		 20.6							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97672	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97672&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821881	164038916							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342687	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)	XYFPWWZEPKGCCK-UHFFFAOYSA-N	50357312	IBRUTINIB::US9181263, 1::US9108973, Ref 1::US9278100, 1::US10124003, Ref. Ex. Compound 1::PCI-32765::US10711006, Compound Ibrutinib::US10919899, Ibrutinib::US10835536, Ref. Ex. Comp 1::US10793575, Example ibrutinib::US11186578, Example Ibrutinib::US11078206, Example Ibrutinib::US11407754, Example Ibrutinib::US11339167, Example Ibrutinib::US20230364079, Example Ibrutinib::US20240059694, Compound Ibrutinib::US20240139326, Compound Ibrutinib::US20240358707, Compound 13	Epidermal growth factor receptor	Homo sapiens		 0.5							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821094	136961336			DB09053				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342688	CN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r|	InChI=1S/C28H31N7O2/c1-33(2)16-7-11-24(36)34-17-6-8-21(18-34)35-28-25(27(29)30-19-31-28)26(32-35)20-12-14-23(15-13-20)37-22-9-4-3-5-10-22/h3-5,7,9-15,19,21H,6,8,16-18H2,1-2H3,(H2,29,30,31)	IDIZKFVKMFGLPN-UHFFFAOYSA-N	97675	BDBM698786::US8497277, 15::US9181263, 2::US9278100, 2::US9133201, 15::US8476284, 43	Epidermal growth factor receptor	Homo sapiens		 48.8							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97675	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97675&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49868739	164038919							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342689	CN(CCO)C\C=C\C(=O)N1CCCC(C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C29H33N7O3/c1-34(17-18-37)15-6-10-25(38)35-16-5-7-22(19-35)36-29-26(28(30)31-20-32-29)27(33-36)21-11-13-24(14-12-21)39-23-8-3-2-4-9-23/h2-4,6,8-14,20,22,37H,5,7,15-19H2,1H3,(H2,30,31,32)	PHFLKOZUXLCTPT-UHFFFAOYSA-N	191609	US9181263, 3::US9278100, 3	Epidermal growth factor receptor	Homo sapiens		 74.5							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191609	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191609&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096323	317222888							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342690	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)\C=C\c1c[nH]cn1	InChI=1S/C28H26N8O2/c29-27-25-26(19-8-11-23(12-9-19)38-22-6-2-1-3-7-22)34-36(28(25)33-18-32-27)21-5-4-14-35(16-21)24(37)13-10-20-15-30-17-31-20/h1-3,6-13,15,17-18,21H,4-5,14,16H2,(H,30,31)(H2,29,32,33)	HDANHRSDLMCNQU-UHFFFAOYSA-N	191610	US9181263, 4::US9278100, 4	Epidermal growth factor receptor	Homo sapiens		 487.6							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191610	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191610&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25095805	317222889							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342691	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)\C=C\CN1CCOCC1	InChI=1S/C30H33N7O3/c31-29-27-28(22-10-12-25(13-11-22)40-24-7-2-1-3-8-24)34-37(30(27)33-21-32-29)23-6-4-15-36(20-23)26(38)9-5-14-35-16-18-39-19-17-35/h1-3,5,7-13,21,23H,4,6,14-20H2,(H2,31,32,33)	MADROAFGGPUYNI-UHFFFAOYSA-N	191611	US9181263, 5::US9278100, 5	Epidermal growth factor receptor	Homo sapiens		 326							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191611	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191611&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25095802	317222890							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342692	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCN(CC1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-12-18(13-15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-8-10-20(11-9-17)33-19-6-4-3-5-7-19/h2-11,16,18H,1,12-15H2,(H2,26,27,28)	KALPRSFUZYGTNU-UHFFFAOYSA-N	97678	US8497277, 10::US8497277, 9::US8476284, 9::US9133201, 9::US9181263, 6::US9278100, 6::US20240317756, Compound 6	Epidermal growth factor receptor	Homo sapiens		 60.9							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97678	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97678&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821880	164038922							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342693	CN(C)C\C=C\C(=O)N1CCC(CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C28H31N7O2/c1-33(2)16-6-9-24(36)34-17-14-21(15-18-34)35-28-25(27(29)30-19-31-28)26(32-35)20-10-12-23(13-11-20)37-22-7-4-3-5-8-22/h3-13,19,21H,14-18H2,1-2H3,(H2,29,30,31)	KAKJQMPMDALLHT-UHFFFAOYSA-N	191612	US9181263, 7::US9278100, 7::US20240317756, Compound 7	Epidermal growth factor receptor	Homo sapiens		 268.7							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191612	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191612&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024272	317222891							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342694	CN(C)C\C=C\C(=O)N[C@H]1CC[C@H](CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r,wU:12.15,9.8,(5.41,-.16,;4.32,-1.25,;4.72,-2.74,;2.83,-.85,;1.74,-1.94,;.25,-1.54,;-.84,-2.63,;-.44,-4.12,;-2.32,-2.23,;-2.72,-.74,;-4.21,-.35,;-4.61,1.14,;-3.52,2.23,;-2.03,1.83,;-1.63,.35,;-3.92,3.72,;-3.37,5.16,;-4.56,6.13,;-4.56,7.67,;-3.23,8.44,;-3.23,9.98,;-4.56,10.75,;-4.56,12.29,;-3.23,13.06,;-1.9,12.29,;-.56,13.06,;-.56,14.6,;-1.9,15.37,;-3.23,14.6,;-5.9,9.98,;-5.9,8.44,;-5.85,5.29,;-7.34,5.69,;-7.74,7.17,;-8.43,4.6,;-8.03,3.11,;-6.55,2.71,;-5.46,3.8,)|	InChI=1S/C29H33N7O2/c1-35(2)18-6-9-25(37)33-21-12-14-22(15-13-21)36-29-26(28(30)31-19-32-29)27(34-36)20-10-16-24(17-11-20)38-23-7-4-3-5-8-23/h3-11,16-17,19,21-22H,12-15,18H2,1-2H3,(H,33,37)(H2,30,31,32)	SYFFKWAKQHJCOM-UHFFFAOYSA-N	191613	US9181263, 8::US9278100, 8	Epidermal growth factor receptor	Homo sapiens		 83.4							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191613&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024093	317222892							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342695	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C |r,wU:23			97672	US8476284, 40::US9133201, 10::US9181263, 9::US9278100, 9::US20240317756, Compound 9::US20240358707, Compound 10	Epidermal growth factor receptor	Homo sapiens		 20.6							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97672	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97672&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821881	164038916							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342696	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@H]1CC[C@@H](CC1)NC(=O)C=C |r,wU:23.26,wD:26.33,(-8.87,3.22,;-8.1,1.89,;-8.87,.55,;-8.1,-.78,;-6.56,-.78,;-5.79,.55,;-4.28,.87,;-4.12,2.4,;-5.53,3.03,;-5.93,4.52,;-4.84,5.61,;-5.24,7.1,;-6.72,7.49,;-7.12,8.98,;-6.03,10.07,;-4.55,9.67,;-3.46,10.76,;-3.86,12.25,;-5.34,12.65,;-6.43,11.56,;-7.81,6.4,;-7.41,4.92,;-6.56,1.89,;-2.95,.1,;-1.62,.87,;-.28,.1,;-.28,-1.44,;-1.62,-2.21,;-2.95,-1.44,;1.05,-2.21,;2.39,-1.44,;2.39,.1,;3.72,-2.21,;5.05,-1.44,)|	InChI=1S/C26H26N6O2/c1-2-22(33)30-18-10-12-19(13-11-18)32-26-23(25(27)28-16-29-26)24(31-32)17-8-14-21(15-9-17)34-20-6-4-3-5-7-20/h2-9,14-16,18-19H,1,10-13H2,(H,30,33)(H2,27,28,29)	SSDFTYWIYVWCIE-UHFFFAOYSA-N	191614	US9181263, 10::US9278100, 10::US20240317756, Compound 10	Epidermal growth factor receptor	Homo sapiens		 44.5							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191614	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191614&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821881	317222893							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342697	CN(C)C\C=C\C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C28H31N7O2/c1-33(2)16-7-11-24(36)34-17-6-8-21(34)18-35-28-25(27(29)30-19-31-28)26(32-35)20-12-14-23(15-13-20)37-22-9-4-3-5-10-22/h3-5,7,9-15,19,21H,6,8,16-18H2,1-2H3,(H2,29,30,31)	DINVXRZOGZOFRM-UHFFFAOYSA-N	191608	US9181263, 11	Epidermal growth factor receptor	Homo sapiens		 18.85							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191608&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58432963	317222887							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342698	CN(C)C\C=C\C(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r|	InChI=1S/C28H31N7O2/c1-33(2)16-7-11-24(36)34-17-6-8-21(34)18-35-28-25(27(29)30-19-31-28)26(32-35)20-12-14-23(15-13-20)37-22-9-4-3-5-10-22/h3-5,7,9-15,19,21H,6,8,16-18H2,1-2H3,(H2,29,30,31)	DINVXRZOGZOFRM-UHFFFAOYSA-N	191616	US9181263, 12::US9278100, 12::US20240317756, Compound 12	Epidermal growth factor receptor	Homo sapiens		 698.3							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191616&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24970289	317222894							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342699	Nc1ncnc2n(C[C@H]3CCCN3C(=O)C=C)nc(-c3ccc(Oc4ccccc4)cc3)c12 |r|	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(30)15-31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)	MWNASUNUUFWMNK-UHFFFAOYSA-N	191617	US9181263, 13::US9278100, 13::US20240317756, Compound 13	Epidermal growth factor receptor	Homo sapiens		 18.75							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191617&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096066	317222895							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342700	Nc1ncnc2n(C[C@@H]3CCCN3C(=O)C=C)nc(-c3ccc(Oc4ccccc4)cc3)c12 |r|	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(30)15-31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)	MWNASUNUUFWMNK-UHFFFAOYSA-N	191605	US9181263, 14::US9278100, 14::US20240317756, Compound 14	Epidermal growth factor receptor	Homo sapiens		 2.298							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191605	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191605&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096065	317222885							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342701	CC#CC(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r|	InChI=1S/C26H24N6O2/c1-2-7-22(33)31-15-6-8-19(31)16-32-26-23(25(27)28-17-29-26)24(30-32)18-11-13-21(14-12-18)34-20-9-4-3-5-10-20/h3-5,9-14,17,19H,6,8,15-16H2,1H3,(H2,27,28,29)	MCHPKOULFPNIOZ-UHFFFAOYSA-N	191619	US9181263, 15::US9278100, 15::US20240317756, Compound 15	Epidermal growth factor receptor	Homo sapiens		 289.4							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191619	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191619&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096067	317222896							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342702	CC#CC(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r|	InChI=1S/C26H24N6O2/c1-2-7-22(33)31-15-6-8-19(31)16-32-26-23(25(27)28-17-29-26)24(30-32)18-11-13-21(14-12-18)34-20-9-4-3-5-10-20/h3-5,9-14,17,19H,6,8,15-16H2,1H3,(H2,27,28,29)	MCHPKOULFPNIOZ-UHFFFAOYSA-N	191620	US9181263, 16::US9278100, 16::US20240317756, Compound 16	Epidermal growth factor receptor	Homo sapiens		 2807							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191620&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096068	317222897							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342703	CC#CC(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r|	InChI=1S/C26H24N6O2/c1-2-7-22(33)31-15-6-8-19(16-31)32-26-23(25(27)28-17-29-26)24(30-32)18-11-13-21(14-12-18)34-20-9-4-3-5-10-20/h3-5,9-14,17,19H,6,8,15-16H2,1H3,(H2,27,28,29)	KEOXYNOFRLIAAM-UHFFFAOYSA-N	191621	US9181263, 17::US9278100, 17::US20240317756, Compound 17	Epidermal growth factor receptor	Homo sapiens		 435.3							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191621	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191621&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66678435	317222898							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342704	CN(C)C\C=C\C(=O)N[C@H]1CC[C@@H](CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r,wU:12.15,wD:9.8,(5.67,1.62,;4.9,.28,;5.67,-1.05,;3.36,.28,;2.59,-1.05,;1.05,-1.05,;.28,-2.39,;1.05,-3.72,;-1.26,-2.39,;-2.03,-1.05,;-1.26,.28,;-2.03,1.62,;-3.57,1.62,;-4.34,.28,;-3.57,-1.05,;-4.34,2.95,;-3.79,4.39,;-4.98,5.36,;-4.98,6.9,;-3.65,7.67,;-3.65,9.21,;-4.98,9.98,;-4.98,11.52,;-3.65,12.29,;-2.32,11.52,;-.98,12.29,;-.98,13.83,;-2.32,14.6,;-3.65,13.83,;-6.32,9.21,;-6.32,7.67,;-6.27,4.52,;-7.76,4.92,;-8.16,6.4,;-8.85,3.83,;-8.45,2.34,;-6.97,1.94,;-5.88,3.03,)|	InChI=1S/C29H33N7O2/c1-35(2)18-6-9-25(37)33-21-12-14-22(15-13-21)36-29-26(28(30)31-19-32-29)27(34-36)20-10-16-24(17-11-20)38-23-7-4-3-5-8-23/h3-11,16-17,19,21-22H,12-15,18H2,1-2H3,(H,33,37)(H2,30,31,32)	SYFFKWAKQHJCOM-UHFFFAOYSA-N	191622	US9181263, 18	Epidermal growth factor receptor	Homo sapiens		 22.53							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191622&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024093	317222899							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342705	CN(CCn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12)C(=O)C=C	InChI=1S/C23H22N6O2/c1-3-19(30)28(2)13-14-29-23-20(22(24)25-15-26-23)21(27-29)16-9-11-18(12-10-16)31-17-7-5-4-6-8-17/h3-12,15H,1,13-14H2,2H3,(H2,24,25,26)	ZFHREWWRBHSDLZ-UHFFFAOYSA-N	191623	US9181263, 19::US9278100, 19::US20240317756, Compound 19	Epidermal growth factor receptor	Homo sapiens		 28.22							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191623	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191623&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024469	317222900							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342706	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCN(CC1)C(=O)\C=C\CN1CCOCC1	InChI=1S/C30H33N7O3/c31-29-27-28(22-8-10-25(11-9-22)40-24-5-2-1-3-6-24)34-37(30(27)33-21-32-29)23-12-15-36(16-13-23)26(38)7-4-14-35-17-19-39-20-18-35/h1-11,21,23H,12-20H2,(H2,31,32,33)	NIKYELXINWPOQX-UHFFFAOYSA-N	191624	US9181263, 20::US9278100, 20::US20240317756, Compound 20	Epidermal growth factor receptor	Homo sapiens		 303.6							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191624	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191624&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096320	317222901							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342707	Nc1ncnc2n(C[C@@H]3CCCN3C(=O)\C=C\CN3CCOCC3)nc(-c3ccc(Oc4ccccc4)cc3)c12 |r|	InChI=1S/C30H33N7O3/c31-29-27-28(22-10-12-25(13-11-22)40-24-7-2-1-3-8-24)34-37(30(27)33-21-32-29)20-23-6-4-15-36(23)26(38)9-5-14-35-16-18-39-19-17-35/h1-3,5,7-13,21,23H,4,6,14-20H2,(H2,31,32,33)	CZCUSNQZHNYXNJ-UHFFFAOYSA-N	191625	US9181263, 21::US9278100, 21::US20240317756, Compound 21	Epidermal growth factor receptor	Homo sapiens		 6238							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191625	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191625&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096321	317222902							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342708	CC#CC(=O)N[C@H]1CC[C@H](CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r,wU:9.12,6.5,(4.06,2.48,;3.67,1,;3.27,-.49,;2.87,-1.98,;3.96,-3.07,;1.38,-2.38,;.29,-1.29,;-1.2,-1.69,;-2.28,-.6,;-1.89,.89,;-.4,1.29,;.69,.2,;-2.98,1.98,;-2.42,3.42,;-3.62,4.39,;-3.62,5.93,;-2.29,6.7,;-2.29,8.24,;-3.62,9.01,;-3.62,10.55,;-2.29,11.32,;-.95,10.55,;.38,11.32,;.38,12.86,;-.95,13.63,;-2.29,12.86,;-4.95,8.24,;-4.95,6.7,;-4.91,3.55,;-6.4,3.95,;-6.8,5.43,;-7.49,2.86,;-7.09,1.37,;-5.6,.97,;-4.51,2.06,)|	InChI=1S/C27H26N6O2/c1-2-6-23(34)31-19-11-13-20(14-12-19)33-27-24(26(28)29-17-30-27)25(32-33)18-9-15-22(16-10-18)35-21-7-4-3-5-8-21/h3-5,7-10,15-17,19-20H,11-14H2,1H3,(H,31,34)(H2,28,29,30)	PTPSYWCHGKIOKO-UHFFFAOYSA-N	191626	US9181263, 22::US9278100, 22::US20240317756, Compound 22	Epidermal growth factor receptor	Homo sapiens		 156.3							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191626&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25095803	317222903							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342709	Nc1ncnc2n(CCNC(=O)C=C)nc(-c3ccc(Oc4ccccc4)cc3)c12	InChI=1S/C22H20N6O2/c1-2-18(29)24-12-13-28-22-19(21(23)25-14-26-22)20(27-28)15-8-10-17(11-9-15)30-16-6-4-3-5-7-16/h2-11,14H,1,12-13H2,(H,24,29)(H2,23,25,26)	ZAZQUFKQXMNBTJ-UHFFFAOYSA-N	191606	US9181263, 23::US9278100, 23::US20240317756, Compound 23	Epidermal growth factor receptor	Homo sapiens		 70.49							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191606	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191606&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024472	317222886							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342710	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)\C=C\CN1CCOCC1 |r|	InChI=1S/C30H33N7O3/c31-29-27-28(22-10-12-25(13-11-22)40-24-7-2-1-3-8-24)34-37(30(27)33-21-32-29)23-6-4-15-36(20-23)26(38)9-5-14-35-16-18-39-19-17-35/h1-3,5,7-13,21,23H,4,6,14-20H2,(H2,31,32,33)	MADROAFGGPUYNI-UHFFFAOYSA-N	191628	US9181263, 24::US9278100, 24::US20240317756, Compound 24	Epidermal growth factor receptor	Homo sapiens		 383.7							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191628	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191628&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66687479	317222904							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
342711	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)\C=C\CN1CCOCC1 |r,wU:23.26,26.33,(-9.32,6.4,;-8.92,4.92,;-10.01,3.83,;-9.61,2.34,;-8.12,1.94,;-7.03,3.03,;-5.49,2.95,;-4.94,4.39,;-6.14,5.36,;-6.14,6.9,;-4.8,7.67,;-4.8,9.21,;-6.14,9.98,;-6.14,11.52,;-4.8,12.29,;-3.47,11.52,;-2.14,12.29,;-2.14,13.83,;-3.47,14.6,;-4.8,13.83,;-7.47,9.21,;-7.47,7.67,;-7.43,4.52,;-4.72,1.62,;-5.49,.28,;-4.72,-1.05,;-3.18,-1.05,;-2.41,.28,;-3.18,1.62,;-2.41,-2.39,;-.87,-2.39,;-.1,-3.72,;-.1,-1.05,;1.44,-1.05,;2.21,.28,;3.75,.28,;4.52,1.62,;6.06,1.62,;6.83,.28,;6.06,-1.05,;4.52,-1.05,)|	InChI=1S/C31H35N7O3/c32-30-28-29(22-8-14-26(15-9-22)41-25-5-2-1-3-6-25)36-38(31(28)34-21-33-30)24-12-10-23(11-13-24)35-27(39)7-4-16-37-17-19-40-20-18-37/h1-9,14-15,21,23-24H,10-13,16-20H2,(H,35,39)(H2,32,33,34)	QWEKIGQOBHAQDZ-UHFFFAOYSA-N	191629	US9181263, 25::US9278100, 25::US20240317756, Compound 25	Epidermal growth factor receptor	Homo sapiens		 272.9							US Patent		10.7270/Q2765D5Z		aid1801874	US9181263	Honigberg, L; Verner, E; Buggy, JJ; Loury, D; Chen, W	11/10/2015	9/6/2016	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191629	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191629&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66687269	317222905							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
344203	CO[C@@H]1COC2[C@@H](COC12)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C |r|	InChI=1S/C27H29ClFN5O5/c1-34(2)8-4-5-24(35)33-20-10-16-19(30-14-31-27(16)32-15-6-7-18(29)17(28)9-15)11-21(20)39-23-13-38-25-22(36-3)12-37-26(23)25/h4-7,9-11,14,22-23,25-26H,8,12-13H2,1-3H3,(H,33,35)(H,30,31,32)	JEMSOXTWRRHLSY-UHFFFAOYSA-N	192316	US9187459, 1	Epidermal growth factor receptor	Homo sapiens		 0.4						25.00 C	US Patent		10.7270/Q25719TF		aid1801898	US9187459	Shen, W; Xiao, W; Maung, J; Zhang, A; Zheng, X; Wang, Z; Guo, Q; Li, Y	11/17/2015	9/12/2016	Newgen Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=192316	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=192316&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121596253	317227919							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
344204	CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1C2COCC12	InChI=1S/C26H27ClFN5O3/c1-33(2)7-3-4-25(34)32-23-9-16-22(10-24(23)36-13-19-17-11-35-12-18(17)19)29-14-30-26(16)31-15-5-6-21(28)20(27)8-15/h3-6,8-10,14,17-19H,7,11-13H2,1-2H3,(H,32,34)(H,29,30,31)	YFQGFLOTVWXVMG-UHFFFAOYSA-N	192317	US9187459, 2	Epidermal growth factor receptor	Homo sapiens		 0.13						25.00 C	US Patent		10.7270/Q25719TF		aid1801898	US9187459	Shen, W; Xiao, W; Maung, J; Zhang, A; Zheng, X; Wang, Z; Guo, Q; Li, Y	11/17/2015	9/12/2016	Newgen Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=192317	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=192317&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71014491	317227920							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
344205	CN(C)CC\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@@]12C[C@@H]1COC2 |r|	InChI=1S/C27H29ClFN5O3/c1-34(2)8-4-3-5-25(35)33-23-10-19-22(11-24(23)37-15-27-12-17(27)13-36-14-27)30-16-31-26(19)32-18-6-7-21(29)20(28)9-18/h3,5-7,9-11,16-17H,4,8,12-15H2,1-2H3,(H,33,35)(H,30,31,32)	LKPIQEOIBNBGGY-UHFFFAOYSA-N	192318	US9187459, 3	Epidermal growth factor receptor	Homo sapiens		 0.54						25.00 C	US Patent		10.7270/Q25719TF		aid1801898	US9187459	Shen, W; Xiao, W; Maung, J; Zhang, A; Zheng, X; Wang, Z; Guo, Q; Li, Y	11/17/2015	9/12/2016	Newgen Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=192318	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=192318&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121596254	317227921							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
344206	CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@]12C[C@H]1COC2 |r|	InChI=1S/C26H27ClFN5O3/c1-33(2)7-3-4-24(34)32-22-9-18-21(10-23(22)36-14-26-11-16(26)12-35-13-26)29-15-30-25(18)31-17-5-6-20(28)19(27)8-17/h3-6,8-10,15-16H,7,11-14H2,1-2H3,(H,32,34)(H,29,30,31)	VPBAXWOWGZTFTQ-UHFFFAOYSA-N	192319	US9187459, 4	Epidermal growth factor receptor	Homo sapiens		 0.51						25.00 C	US Patent		10.7270/Q25719TF		aid1801898	US9187459	Shen, W; Xiao, W; Maung, J; Zhang, A; Zheng, X; Wang, Z; Guo, Q; Li, Y	11/17/2015	9/12/2016	Newgen Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=192319	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=192319&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71618040	317227922							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
344207	CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC12CC1COC2	InChI=1S/C26H27ClFN5O3/c1-33(2)7-3-4-24(34)32-22-9-18-21(10-23(22)36-14-26-11-16(26)12-35-13-26)29-15-30-25(18)31-17-5-6-20(28)19(27)8-17/h3-6,8-10,15-16H,7,11-14H2,1-2H3,(H,32,34)(H,29,30,31)	VPBAXWOWGZTFTQ-UHFFFAOYSA-N	192320	US9187459, 5	Epidermal growth factor receptor	Homo sapiens		 0.37						25.00 C	US Patent		10.7270/Q25719TF		aid1801898	US9187459	Shen, W; Xiao, W; Maung, J; Zhang, A; Zheng, X; Wang, Z; Guo, Q; Li, Y	11/17/2015	9/12/2016	Newgen Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=192320	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=192320&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71014204	317227923							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A,8A27,8HY7,8HV5,8HV3,8HV1,7OXB,5Y25,5HIC,5HIB,5HCZ,5HCY,5HCX,5EM7,5EM6,5EM5	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358422	COc1ccccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H18F3N5O2/c1-3-18(30)26-13-7-6-8-14(11-13)27-19-15(21(22,23)24)12-25-20(29-19)28-16-9-4-5-10-17(16)31-2/h3-12H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	ARSGAAANDMOADX-UHFFFAOYSA-N	202369	US10081606, Compound I-1::US9238629, I-1::US9765038, Compound I-1	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56965025	319495463							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358423	COc1ccccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H17F3N4O3/c1-3-18(29)26-13-7-6-8-14(11-13)31-19-15(21(22,23)24)12-25-20(28-19)27-16-9-4-5-10-17(16)30-2/h3-12H,1H2,2H3,(H,26,29)(H,25,27,28)	KGGXRCWBXUHQBM-UHFFFAOYSA-N	202370	US10081606, Compound I-2::US9238629, I-2::US9765038, Compound I-2	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336077	319495464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358424	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H20F3N5O3/c1-4-19(31)27-13-6-5-7-14(10-13)28-20-16(22(23,24)25)12-26-21(30-20)29-17-9-8-15(32-2)11-18(17)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	ARWJHMPQGVRJGR-UHFFFAOYSA-N	202371	US10081606, Compound I-3::US9238629, I-3::US9765038, Compound I-3	Epidermal growth factor receptor	Homo sapiens		 20					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336078	319495465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358425	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22ClN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	AWLYEWOENDLBPJ-UHFFFAOYSA-N	202372	US10081606, Compound I-4::US9238629, I-4::US9765038, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 65					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336218	319495466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358426	COc1ccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22BrN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	UKFLBAQMJNODAB-UHFFFAOYSA-N	202373	US10081606, Compound I-5::US9238629, I-5::US9765038, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 65					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336219	319495467							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358427	COc1cccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H19BrN4O4/c1-4-18(27)24-13-7-5-8-14(11-13)30-20-15(22)12-23-21(26-20)25-16-9-6-10-17(28-2)19(16)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	MOQWLDSTRHMSCL-UHFFFAOYSA-N	202374	US10081606, Compound I-6::US9238629, I-14::US9238629, I-6::US9765038, Compound I-6	Epidermal growth factor receptor	Homo sapiens		 650					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336220	319495468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358428	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21ClN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	KKXHOHZIJWZIMH-UHFFFAOYSA-N	202375	US10081606, Compound I-7::US9238629, I-7::US9765038, Compound I-7	Epidermal growth factor receptor	Homo sapiens		 20					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336221	319495469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358429	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21BrN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	YVPOPEGFKSLPQP-UHFFFAOYSA-N	202376	US10081606, Compound I-8::US9238629, I-8::US9765038, Compound I-8	Epidermal growth factor receptor	Homo sapiens		 65					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336222	319495470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358430	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H19F3N4O4/c1-4-19(30)27-13-6-5-7-15(10-13)33-20-16(22(23,24)25)12-26-21(29-20)28-17-9-8-14(31-2)11-18(17)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	YQRLADVWFUXYQX-UHFFFAOYSA-N	202377	US10081606, Compound I-9::US9238629, I-9::US9765038, Compound I-9	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336223	319495471							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358431	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H21F3N4O5/c1-5-18(31)28-13-7-6-8-14(11-13)35-21-15(23(24,25)26)12-27-22(30-21)29-16-9-10-17(32-2)20(34-4)19(16)33-3/h5-12H,1H2,2-4H3,(H,28,31)(H,27,29,30)	BJXUJZVUNLHQJX-UHFFFAOYSA-N	202378	US10081606, Compound I-10::US9238629, I-10::US9765038, Compound I-10	Epidermal growth factor receptor	Homo sapiens		 65					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202378&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333995	319495472							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358432	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H22F3N5O4/c1-5-18(32)28-13-7-6-8-14(11-13)29-21-15(23(24,25)26)12-27-22(31-21)30-16-9-10-17(33-2)20(35-4)19(16)34-3/h5-12H,1H2,2-4H3,(H,28,32)(H2,27,29,30,31)	XTEXGVCQXOYDOW-UHFFFAOYSA-N	202379	US10081606, Compound I-11::US9238629, I-11::US9765038, Compound I-11	Epidermal growth factor receptor	Homo sapiens		 20					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333996	319495473							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358433	COc1ccccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H17ClN4O3/c1-3-18(26)23-13-7-6-8-14(11-13)28-19-15(21)12-22-20(25-19)24-16-9-4-5-10-17(16)27-2/h3-12H,1H2,2H3,(H,23,26)(H,22,24,25)	DSRXZMGDJDQWJM-UHFFFAOYSA-N	202380	US10081606, Compound I-12::US9238629, I-12::US9765038, Compound I-12	Epidermal growth factor receptor	Homo sapiens		 650					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333997	319495474							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358434	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19BrN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	OKWMEKZLQMLGEO-UHFFFAOYSA-N	202381	US10081606, Compound I-13::US9238629, I-13::US9765038, Compound I-13	Epidermal growth factor receptor	Homo sapiens		 65					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333998	319495475							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358435	COc1cccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H19BrN4O4/c1-4-18(27)24-13-7-5-8-14(11-13)30-20-15(22)12-23-21(26-20)25-16-9-6-10-17(28-2)19(16)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	MOQWLDSTRHMSCL-UHFFFAOYSA-N	202374	US10081606, Compound I-6::US9238629, I-14::US9238629, I-6::US9765038, Compound I-6	Epidermal growth factor receptor	Homo sapiens		 650					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336220	319495468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358436	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19ClN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	UVQSPGYTMSYCFZ-UHFFFAOYSA-N	202383	US10081606, Compound I-15::US9238629, I-15::US9765038, Compound I-15	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334000	319495476							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358437	COc1cccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H20F3N5O3/c1-4-18(31)27-13-7-5-8-14(11-13)28-20-15(22(23,24)25)12-26-21(30-20)29-16-9-6-10-17(32-2)19(16)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	NBLFLERZTPRKQT-UHFFFAOYSA-N	202384	US10081606, Compound I-16::US9238629, I-16::US9765038, Compound I-16	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334304	319495477							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358438	COc1cccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H20ClN5O3/c1-4-18(28)24-13-7-5-8-14(11-13)25-20-15(22)12-23-21(27-20)26-16-9-6-10-17(29-2)19(16)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	BHJUAKDTALSDNG-UHFFFAOYSA-N	202385	US9238629, I-17	Epidermal growth factor receptor	Homo sapiens		 650					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202385&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			67966801	319495478							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358439	COc1ccccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H18ClN5O2/c1-3-18(27)23-13-7-6-8-14(11-13)24-19-15(21)12-22-20(26-19)25-16-9-4-5-10-17(16)28-2/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	IJBMVFJGJFRXOX-UHFFFAOYSA-N	202386	US10081606, Compound I-18::US9238629, I-18::US9765038, Compound I-18	Epidermal growth factor receptor	Homo sapiens		 650					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334158	319495479							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358440	COc1ccccc1Nc1ncc(F)c(Oc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H17FN4O3/c1-3-18(26)23-13-7-6-8-14(11-13)28-19-15(21)12-22-20(25-19)24-16-9-4-5-10-17(16)27-2/h3-12H,1H2,2H3,(H,23,26)(H,22,24,25)	XSYRRKUEQTWUCQ-UHFFFAOYSA-N	202387	US10081606, Compound I-19::US9238629, I-19::US9765038, Compound I-19	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334159	319495480							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358441	COc1ccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H20BrN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-17-9-8-15(29-2)11-18(17)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	HPWXLWYAEGDGKI-UHFFFAOYSA-N	202388	US10081606, Compound I-20::US9238629, I-20::US9765038, Compound I-20	Epidermal growth factor receptor	Homo sapiens		 65					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202388&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334160	319495481							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358442	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H20ClN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-17-9-8-15(29-2)11-18(17)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	UGZHYAQGGADKAK-UHFFFAOYSA-N	202389	US10081606, Compound I-21::US9238629, I-21::US9765038, Compound I-21	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334161	319495482							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358443	COc1ccccc1Nc1ncc(Br)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H18BrN5O2/c1-3-18(27)23-13-7-6-8-14(11-13)24-19-15(21)12-22-20(26-19)25-16-9-4-5-10-17(16)28-2/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	FMTXHOXUJYVAMG-UHFFFAOYSA-N	202390	US10081606, Compound I-22::US9238629, I-22::US9765038, Compound I-22	Epidermal growth factor receptor	Homo sapiens		 200					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202390&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334303	319495483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
358444	COc1cccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H19F3N4O4/c1-4-18(30)27-13-7-5-8-14(11-13)33-20-15(22(23,24)25)12-26-21(29-20)28-16-9-6-10-17(31-2)19(16)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	HIMGGUFXIBERNV-UHFFFAOYSA-N	202391	US10081606, Compound I-23::US9238629, I-23::US9765038, Compound I-23	Epidermal growth factor receptor	Homo sapiens		>1000					7.5	25.00 C	US Patent		10.7270/Q2P849Q7		aid1802136	US9238629	Lee, K; Niu, D; Petter, RC; Singh, J	1/19/2016	11/21/2016	Celgene Avilomics Research, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202391&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334156	319495484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
370863	C[C@H]1CC[C@H](CN1C(=O)C=C)Nc1ncnc2[nH]ccc12			209866	PF-06651600::US11111242, Example 5::US9617258, Example 5	Epidermal growth factor receptor	Homo sapiens		>50000					7.4	25.00 C	Curated from the literature by BindingDB	10.1021/acschembio.6b00677	10.7270/Q2PN94F8	27791347	aid1802325		Telliez, JB; Dowty, ME; Wang, L; Jussif, J; Lin, T; Li, L; Moy, E; Balbo, P; Li, W; Zhao, Y; Crouse, K; Dickinson, C; Symanowicz, P; Hegen, M; Banker, ME; Vincent, F; Unwalla, R; Liang, S; Gilbert, AM; Brown, MF; Hayward, M; Montgomery, J; Yang, X; Bauman, J; Trujillo, JI; Casimiro-Garcia, A; Vajdos, FF; Leung, L; Geoghegan, KF; Quazi, A; Xuan, D; Jones, L; Hett, E; Wright, K; Clark, JD; Thorarensen, A	12/16/2016	1/23/2017	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=209866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=209866&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115473	328082845							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
384997	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m1/s1	XYFPWWZEPKGCCK-GOSISDBHSA-N	50357312	IBRUTINIB::PCI-32765::US10124003, Ref. Ex. Compound 1::US10711006, Compound Ibrutinib::US10793575, Example ibrutinib::US10835536, Ref. Ex. Comp 1::US10919899, Ibrutinib::US11078206, Example Ibrutinib::US11186578, Example Ibrutinib::US11339167, Example Ibrutinib::US11407754, Example Ibrutinib::US9108973, Ref 1::US9181263, 1::US9278100, 1	Epidermal growth factor receptor	Homo sapiens		 0.5							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1E8	5YU9,4IFG,6YG2,6YZ4,4RZ7,6L8L,5P9I	24821094	136961336			DB09053			ZINC35328014	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385018	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C	InChI=1S/C26H26N6O2/c1-2-22(33)30-18-10-12-19(13-11-18)32-26-23(25(27)28-16-29-26)24(31-32)17-8-14-21(15-9-17)34-20-6-4-3-5-7-20/h2-9,14-16,18-19H,1,10-13H2,(H,30,33)(H2,27,28,29)/t18-,19+	SSDFTYWIYVWCIE-KDURUIRLSA-N	97672	US8476284, 40::US9133201, 10::US9181263, 9::US9278100, 9	Epidermal growth factor receptor	Homo sapiens		 20.6							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97672&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821881	164038916						ZINC96167578	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385079	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m1/s1	XYFPWWZEPKGCCK-GOSISDBHSA-N	50357312	IBRUTINIB::PCI-32765::US10124003, Ref. Ex. Compound 1::US10711006, Compound Ibrutinib::US10793575, Example ibrutinib::US10835536, Ref. Ex. Comp 1::US10919899, Ibrutinib::US11078206, Example Ibrutinib::US11186578, Example Ibrutinib::US11339167, Example Ibrutinib::US11407754, Example Ibrutinib::US9108973, Ref 1::US9181263, 1::US9278100, 1	Epidermal growth factor receptor	Homo sapiens		 0.5							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	1E8	5YU9,4IFG,6YG2,6YZ4,4RZ7,6L8L,5P9I	24821094	136961336			DB09053			ZINC35328014	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385080	CN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C28H31N7O2/c1-33(2)16-7-11-24(36)34-17-6-8-21(18-34)35-28-25(27(29)30-19-31-28)26(32-35)20-12-14-23(15-13-20)37-22-9-4-3-5-10-22/h3-5,7,9-15,19,21H,6,8,16-18H2,1-2H3,(H2,29,30,31)/b11-7+/t21-/m1/s1	IDIZKFVKMFGLPN-FTUXVVSKSA-N	97675	US8476284, 43::US8497277, 15::US9133201, 15::US9181263, 2::US9278100, 2	Epidermal growth factor receptor	Homo sapiens		 48.8							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97675&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49868739	164038919						ZINC96167584	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385081	CN(CCO)C\C=C\C(=O)N1CCCC(C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C29H33N7O3/c1-34(17-18-37)15-6-10-25(38)35-16-5-7-22(19-35)36-29-26(28(30)31-20-32-29)27(33-36)21-11-13-24(14-12-21)39-23-8-3-2-4-9-23/h2-4,6,8-14,20,22,37H,5,7,15-19H2,1H3,(H2,30,31,32)/b10-6+	PHFLKOZUXLCTPT-UXBLZVDNSA-N	191609	US9181263, 3::US9278100, 3	Epidermal growth factor receptor	Homo sapiens		 74.5							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191609&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096323	317222888							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385082	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)\C=C\c1c[nH]cn1			191610	US9181263, 4::US9278100, 4	Epidermal growth factor receptor	Homo sapiens		 487.6							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191610&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25095805	317222889							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385083	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)\C=C\CN1CCOCC1	InChI=1S/C30H33N7O3/c31-29-27-28(22-10-12-25(13-11-22)40-24-7-2-1-3-8-24)34-37(30(27)33-21-32-29)23-6-4-15-36(20-23)26(38)9-5-14-35-16-18-39-19-17-35/h1-3,5,7-13,21,23H,4,6,14-20H2,(H2,31,32,33)/b9-5+	MADROAFGGPUYNI-WEVVVXLNSA-N	191611	US9181263, 5::US9278100, 5	Epidermal growth factor receptor	Homo sapiens		 326							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191611&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25095802	317222890							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385084	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCN(CC1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-12-18(13-15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-8-10-20(11-9-17)33-19-6-4-3-5-7-19/h2-11,16,18H,1,12-15H2,(H2,26,27,28)	KALPRSFUZYGTNU-UHFFFAOYSA-N	97678	US8476284, 9::US8497277, 10::US8497277, 9::US9133201, 9::US9181263, 6::US9278100, 6	Epidermal growth factor receptor	Homo sapiens		 60.9							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97678&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821880	164038922							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385085	CN(C)C\C=C\C(=O)N1CCC(CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C28H31N7O2/c1-33(2)16-6-9-24(36)34-17-14-21(15-18-34)35-28-25(27(29)30-19-31-28)26(32-35)20-10-12-23(13-11-20)37-22-7-4-3-5-8-22/h3-13,19,21H,14-18H2,1-2H3,(H2,29,30,31)/b9-6+	KAKJQMPMDALLHT-RMKNXTFCSA-N	191612	US9181263, 7::US9278100, 7	Epidermal growth factor receptor	Homo sapiens		 268.7							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191612&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024272	317222891							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385086	CN(C)C\C=C\C(=O)N[C@H]1CC[C@H](CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C29H33N7O2/c1-35(2)18-6-9-25(37)33-21-12-14-22(15-13-21)36-29-26(28(30)31-19-32-29)27(34-36)20-10-16-24(17-11-20)38-23-7-4-3-5-8-23/h3-11,16-17,19,21-22H,12-15,18H2,1-2H3,(H,33,37)(H2,30,31,32)/b9-6+/t21-,22+	SYFFKWAKQHJCOM-YEALQQFWSA-N	191613	US9181263, 8::US9278100, 8	Epidermal growth factor receptor	Homo sapiens		 83.4							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191613&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024093	317222892							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385087	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C	InChI=1S/C26H26N6O2/c1-2-22(33)30-18-10-12-19(13-11-18)32-26-23(25(27)28-16-29-26)24(31-32)17-8-14-21(15-9-17)34-20-6-4-3-5-7-20/h2-9,14-16,18-19H,1,10-13H2,(H,30,33)(H2,27,28,29)/t18-,19+	SSDFTYWIYVWCIE-KDURUIRLSA-N	97672	US8476284, 40::US9133201, 10::US9181263, 9::US9278100, 9	Epidermal growth factor receptor	Homo sapiens		 20.6							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97672&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821881	164038916						ZINC96167578	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385088	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@H]1CC[C@@H](CC1)NC(=O)C=C	InChI=1S/C26H26N6O2/c1-2-22(33)30-18-10-12-19(13-11-18)32-26-23(25(27)28-16-29-26)24(31-32)17-8-14-21(15-9-17)34-20-6-4-3-5-7-20/h2-9,14-16,18-19H,1,10-13H2,(H,30,33)(H2,27,28,29)/t18-,19-	SSDFTYWIYVWCIE-WGSAOQKQSA-N	191614	US9181263, 10::US9278100, 10	Epidermal growth factor receptor	Homo sapiens		 44.5							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191614&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821881	317222893							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385089	CN(C)C\C=C\C(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(C)ncnc12	InChI=1S/C29H32N6O2/c1-21-27-28(22-13-15-25(16-14-22)37-24-10-5-4-6-11-24)32-35(29(27)31-20-30-21)19-23-9-7-18-34(23)26(36)12-8-17-33(2)3/h4-6,8,10-16,20,23H,7,9,17-19H2,1-3H3/b12-8+/t23-/m1/s1	UBDKHMQBZNCDSH-ZRGXPQFDSA-N	220128	US9278100, 11	Epidermal growth factor receptor	Homo sapiens		 18.85							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220128&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			124222780	329995266							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385090	CN(C)C\C=C\C(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C28H31N7O2/c1-33(2)16-7-11-24(36)34-17-6-8-21(34)18-35-28-25(27(29)30-19-31-28)26(32-35)20-12-14-23(15-13-20)37-22-9-4-3-5-10-22/h3-5,7,9-15,19,21H,6,8,16-18H2,1-2H3,(H2,29,30,31)/b11-7+/t21-/m0/s1	DINVXRZOGZOFRM-AKERNLMBSA-N	191616	US9181263, 12::US9278100, 12	Epidermal growth factor receptor	Homo sapiens		 698.3							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191616&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24970289	317222894							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385091	Nc1ncnc2n(C[C@H]3CCCN3C(=O)C=C)nc(-c3ccc(Oc4ccccc4)cc3)c12	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(30)15-31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m1/s1	MWNASUNUUFWMNK-GOSISDBHSA-N	191617	US9181263, 13::US9278100, 13	Epidermal growth factor receptor	Homo sapiens		 18.75							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191617&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096066	317222895							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385092	Nc1ncnc2n(C[C@@H]3CCCN3C(=O)C=C)nc(-c3ccc(Oc4ccccc4)cc3)c12	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(30)15-31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m0/s1	MWNASUNUUFWMNK-SFHVURJKSA-N	191605	US9181263, 14::US9278100, 14	Epidermal growth factor receptor	Homo sapiens		 2.298							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191605&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096065	317222885							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385093	CC#CC(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C26H24N6O2/c1-2-7-22(33)31-15-6-8-19(31)16-32-26-23(25(27)28-17-29-26)24(30-32)18-11-13-21(14-12-18)34-20-9-4-3-5-10-20/h3-5,9-14,17,19H,6,8,15-16H2,1H3,(H2,27,28,29)/t19-/m1/s1	MCHPKOULFPNIOZ-LJQANCHMSA-N	191619	US9181263, 15::US9278100, 15	Epidermal growth factor receptor	Homo sapiens		 289.4							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191619&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096067	317222896							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385094	CC#CC(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C26H24N6O2/c1-2-7-22(33)31-15-6-8-19(31)16-32-26-23(25(27)28-17-29-26)24(30-32)18-11-13-21(14-12-18)34-20-9-4-3-5-10-20/h3-5,9-14,17,19H,6,8,15-16H2,1H3,(H2,27,28,29)/t19-/m0/s1	MCHPKOULFPNIOZ-IBGZPJMESA-N	191620	US9181263, 16::US9278100, 16	Epidermal growth factor receptor	Homo sapiens		 2807							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191620&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096068	317222897							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385095	CC#CC(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C26H24N6O2/c1-2-7-22(33)31-15-6-8-19(16-31)32-26-23(25(27)28-17-29-26)24(30-32)18-11-13-21(14-12-18)34-20-9-4-3-5-10-20/h3-5,9-14,17,19H,6,8,15-16H2,1H3,(H2,27,28,29)/t19-/m1/s1	KEOXYNOFRLIAAM-LJQANCHMSA-N	191621	US9181263, 17::US9278100, 17	Epidermal growth factor receptor	Homo sapiens		 435.3							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191621&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66678435	317222898							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385096	CN(C)C\C=C\C(=O)NC1CC[C@@H](CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C29H33N7O2/c1-35(2)18-6-9-25(37)33-21-12-14-22(15-13-21)36-29-26(28(30)31-19-32-29)27(34-36)20-10-16-24(17-11-20)38-23-7-4-3-5-8-23/h3-11,16-17,19,21-22H,12-15,18H2,1-2H3,(H,33,37)(H2,30,31,32)/b9-6+/t21?,22-	SYFFKWAKQHJCOM-CYAXNICHSA-N	220129	US9278100, 18	Epidermal growth factor receptor	Homo sapiens		 22.53							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220129&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024093	329995267							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385097	CN(CCn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12)C(=O)C=C	InChI=1S/C23H22N6O2/c1-3-19(30)28(2)13-14-29-23-20(22(24)25-15-26-23)21(27-29)16-9-11-18(12-10-16)31-17-7-5-4-6-8-17/h3-12,15H,1,13-14H2,2H3,(H2,24,25,26)	ZFHREWWRBHSDLZ-UHFFFAOYSA-N	191623	US9181263, 19::US9278100, 19	Epidermal growth factor receptor	Homo sapiens		 28.22							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191623&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024469	317222900							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385098	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCN(CC1)C(=O)\C=C\CN1CCOCC1	InChI=1S/C30H33N7O3/c31-29-27-28(22-8-10-25(11-9-22)40-24-5-2-1-3-6-24)34-37(30(27)33-21-32-29)23-12-15-36(16-13-23)26(38)7-4-14-35-17-19-39-20-18-35/h1-11,21,23H,12-20H2,(H2,31,32,33)/b7-4+	NIKYELXINWPOQX-QPJJXVBHSA-N	191624	US9181263, 20::US9278100, 20	Epidermal growth factor receptor	Homo sapiens		 303.6							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191624&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096320	317222901							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385099	Nc1ncnc2n(C[C@@H]3CCCN3C(=O)\C=C\CN3CCOCC3)nc(-c3ccc(Oc4ccccc4)cc3)c12	InChI=1S/C30H33N7O3/c31-29-27-28(22-10-12-25(13-11-22)40-24-7-2-1-3-8-24)34-37(30(27)33-21-32-29)20-23-6-4-15-36(23)26(38)9-5-14-35-16-18-39-19-17-35/h1-3,5,7-13,21,23H,4,6,14-20H2,(H2,31,32,33)/b9-5+/t23-/m0/s1	CZCUSNQZHNYXNJ-LKYAVPRHSA-N	191625	US9181263, 21::US9278100, 21	Epidermal growth factor receptor	Homo sapiens		 6238							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191625&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25096321	317222902							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385100	CC#CC(=O)N[C@H]1CC[C@H](CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12	InChI=1S/C27H26N6O2/c1-2-6-23(34)31-19-11-13-20(14-12-19)33-27-24(26(28)29-17-30-27)25(32-33)18-9-15-22(16-10-18)35-21-7-4-3-5-8-21/h3-5,7-10,15-17,19-20H,11-14H2,1H3,(H,31,34)(H2,28,29,30)/t19-,20+	PTPSYWCHGKIOKO-BGYRXZFFSA-N	191626	US9181263, 22::US9278100, 22	Epidermal growth factor receptor	Homo sapiens		 156.3							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191626&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25095803	317222903							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385101	Nc1ncnc2n(CCNC(=O)C=C)nc(-c3ccc(Oc4ccccc4)cc3)c12	InChI=1S/C22H20N6O2/c1-2-18(29)24-12-13-28-22-19(21(23)25-14-26-22)20(27-28)15-8-10-17(11-9-15)30-16-6-4-3-5-7-16/h2-11,14H,1,12-13H2,(H,24,29)(H2,23,25,26)	ZAZQUFKQXMNBTJ-UHFFFAOYSA-N	191606	US9181263, 23::US9278100, 23	Epidermal growth factor receptor	Homo sapiens		 70.49							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191606&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25024472	317222886							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385102	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)\C=C\CN1CCOCC1	InChI=1S/C30H33N7O3/c31-29-27-28(22-10-12-25(13-11-22)40-24-7-2-1-3-8-24)34-37(30(27)33-21-32-29)23-6-4-15-36(20-23)26(38)9-5-14-35-16-18-39-19-17-35/h1-3,5,7-13,21,23H,4,6,14-20H2,(H2,31,32,33)/b9-5+/t23-/m1/s1	MADROAFGGPUYNI-DXSBJVNVSA-N	191628	US9181263, 24::US9278100, 24	Epidermal growth factor receptor	Homo sapiens		 383.7							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191628&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66687479	317222904							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
385103	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)\C=C\CN1CCOCC1	InChI=1S/C31H35N7O3/c32-30-28-29(22-8-14-26(15-9-22)41-25-5-2-1-3-6-25)36-38(31(28)34-21-33-30)24-12-10-23(11-13-24)35-27(39)7-4-16-37-17-19-40-20-18-37/h1-9,14-15,21,23-24H,10-13,16-20H2,(H,35,39)(H2,32,33,34)/b7-4+/t23-,24+	QWEKIGQOBHAQDZ-WWBGYUKBSA-N	191629	US9181263, 25::US9278100, 25	Epidermal growth factor receptor	Homo sapiens		 272.9							US Patent		10.7270/Q20C4TMX		aid1802525	US9278100	Honigberg, L; Verner, E; Buggy, J; Loury, D; Chen, W	3/8/2016	4/3/2017	Pharmacyclics LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=191629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=191629&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66687269	317222905							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406353	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1C	InChI=1S/C32H31ClN6O3/c1-3-41-30-17-27-25(16-28(30)38-31(40)12-10-24-8-6-14-39(24)2)32(21(18-34)19-36-27)37-22-9-11-29(26(33)15-22)42-20-23-7-4-5-13-35-23/h4-5,7,9-13,15-17,19,24H,3,6,8,14,20H2,1-2H3,(H,36,37)(H,38,40)/b12-10+/t24-/m0/s1	SADXACCFNXBCFY-YKATVRGKSA-N	139988	US8901140, 1::US9358227, 1	Epidermal growth factor receptor	Homo sapiens		 22							US Patent		10.7270/Q2RJ4HB5		aid1802918	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139988	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139988&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038981	250184292							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406354	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1	InChI=1S/C31H29ClN6O3/c1-2-40-29-16-26-24(15-27(29)38-30(39)11-9-21-7-5-13-34-21)31(20(17-33)18-36-26)37-22-8-10-28(25(32)14-22)41-19-23-6-3-4-12-35-23/h3-4,6,8-12,14-16,18,21,34H,2,5,7,13,19H2,1H3,(H,36,37)(H,38,39)/b11-9+/t21-/m0/s1	BXYUWIKGVQXGEA-ZUURVNMSSA-N	139989	US8901140, 2::US9358227, 2	Epidermal growth factor receptor	Homo sapiens		 3							US Patent		10.7270/Q2RJ4HB5		aid1802918	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139989	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139989&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039032	250184293							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406355	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1C[C@@H](O)CN1C	InChI=1S/C32H31ClN6O4/c1-3-42-30-15-27-25(14-28(30)38-31(41)10-8-23-13-24(40)18-39(23)2)32(20(16-34)17-36-27)37-21-7-9-29(26(33)12-21)43-19-22-6-4-5-11-35-22/h4-12,14-15,17,23-24,40H,3,13,18-19H2,1-2H3,(H,36,37)(H,38,41)/b10-8+/t23-,24-/m1/s1	MGJMZWXLGRKRAN-XLGCXCGNSA-N	139990	US8901140, 3::US9358227, 3	Epidermal growth factor receptor	Homo sapiens		 36							US Patent		10.7270/Q2RJ4HB5		aid1802918	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139990	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139990&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038275	250184294							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406356	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C	InChI=1S/C32H31ClN6O3/c1-3-41-30-17-27-25(16-28(30)38-31(40)12-10-24-8-6-14-39(24)2)32(21(18-34)19-36-27)37-22-9-11-29(26(33)15-22)42-20-23-7-4-5-13-35-23/h4-5,7,9-13,15-17,19,24H,3,6,8,14,20H2,1-2H3,(H,36,37)(H,38,40)/b12-10+/t24-/m1/s1	SADXACCFNXBCFY-IYNHSRRRSA-N	139991	US8901140, 5::US9358227, 5	Epidermal growth factor receptor	Homo sapiens		 45							US Patent		10.7270/Q2RJ4HB5		aid1802918	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139991&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039030	250184295							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406357	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C	InChI=1S/C24H25ClFN5O2/c1-3-33-22-13-20-17(12-21(22)30-23(32)9-7-16-5-4-10-31(16)2)24(28-14-27-20)29-15-6-8-19(26)18(25)11-15/h6-9,11-14,16H,3-5,10H2,1-2H3,(H,30,32)(H,27,28,29)/b9-7+/t16-/m1/s1	JZQOPZNZLUYLTR-MNDMWVCDSA-N	139994	US8901140, 9::US9358227, 9	Epidermal growth factor receptor	Homo sapiens		 8							US Patent		10.7270/Q2RJ4HB5		aid1802918	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139994&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039044	250184298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406358	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1C	InChI=1S/C32H31ClN6O3/c1-3-41-30-17-27-25(16-28(30)38-31(40)12-10-24-8-6-14-39(24)2)32(21(18-34)19-36-27)37-22-9-11-29(26(33)15-22)42-20-23-7-4-5-13-35-23/h4-5,7,9-13,15-17,19,24H,3,6,8,14,20H2,1-2H3,(H,36,37)(H,38,40)/b12-10+/t24-/m0/s1	SADXACCFNXBCFY-YKATVRGKSA-N	139988	US8901140, 1::US9358227, 1	Epidermal growth factor receptor	Homo sapiens		 48							US Patent		10.7270/Q2RJ4HB5		aid1802919	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139988	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139988&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038981	250184292							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406359	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1	InChI=1S/C31H29ClN6O3/c1-2-40-29-16-26-24(15-27(29)38-30(39)11-9-21-7-5-13-34-21)31(20(17-33)18-36-26)37-22-8-10-28(25(32)14-22)41-19-23-6-3-4-12-35-23/h3-4,6,8-12,14-16,18,21,34H,2,5,7,13,19H2,1H3,(H,36,37)(H,38,39)/b11-9+/t21-/m0/s1	BXYUWIKGVQXGEA-ZUURVNMSSA-N	139989	US8901140, 2::US9358227, 2	Epidermal growth factor receptor	Homo sapiens		 6							US Patent		10.7270/Q2RJ4HB5		aid1802919	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139989	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139989&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039032	250184293							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406360	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1C[C@@H](O)CN1C	InChI=1S/C32H31ClN6O4/c1-3-42-30-15-27-25(14-28(30)38-31(41)10-8-23-13-24(40)18-39(23)2)32(20(16-34)17-36-27)37-21-7-9-29(26(33)12-21)43-19-22-6-4-5-11-35-22/h4-12,14-15,17,23-24,40H,3,13,18-19H2,1-2H3,(H,36,37)(H,38,41)/b10-8+/t23-,24-/m1/s1	MGJMZWXLGRKRAN-XLGCXCGNSA-N	139990	US8901140, 3::US9358227, 3	Epidermal growth factor receptor	Homo sapiens		 59							US Patent		10.7270/Q2RJ4HB5		aid1802919	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139990	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139990&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038275	250184294							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406361	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C	InChI=1S/C32H31ClN6O3/c1-3-41-30-17-27-25(16-28(30)38-31(40)12-10-24-8-6-14-39(24)2)32(21(18-34)19-36-27)37-22-9-11-29(26(33)15-22)42-20-23-7-4-5-13-35-23/h4-5,7,9-13,15-17,19,24H,3,6,8,14,20H2,1-2H3,(H,36,37)(H,38,40)/b12-10+/t24-/m1/s1	SADXACCFNXBCFY-IYNHSRRRSA-N	139991	US8901140, 5::US9358227, 5	Epidermal growth factor receptor	Homo sapiens		 13							US Patent		10.7270/Q2RJ4HB5		aid1802919	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139991&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039030	250184295							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406362	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\[C@@H]1CCCN1C	InChI=1S/C24H25ClFN5O2/c1-3-33-22-13-20-17(12-21(22)30-23(32)9-7-16-5-4-10-31(16)2)24(28-14-27-20)29-15-6-8-19(26)18(25)11-15/h6-9,11-14,16H,3-5,10H2,1-2H3,(H,30,32)(H,27,28,29)/b9-7+/t16-/m0/s1	JZQOPZNZLUYLTR-DYLHUKMJSA-N	139992	US8901140, 7::US9358227, 7	Epidermal growth factor receptor	Homo sapiens		 4							US Patent		10.7270/Q2RJ4HB5		aid1802919	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139992&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039031	250184296							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406363	COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C	InChI=1S/C25H27ClFN5O3/c1-32-9-3-4-17(32)6-8-24(33)31-22-13-18-21(14-23(22)35-11-10-34-2)28-15-29-25(18)30-16-5-7-20(27)19(26)12-16/h5-8,12-15,17H,3-4,9-11H2,1-2H3,(H,31,33)(H,28,29,30)/b8-6+/t17-/m1/s1	JLZPLOMYCANQFI-DBWMJRBXSA-N	139993	US8901140, 8::US9358227, 8	Epidermal growth factor receptor	Homo sapiens		 2							US Patent		10.7270/Q2RJ4HB5		aid1802919	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139993&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51038277	250184297							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406364	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C	InChI=1S/C24H25ClFN5O2/c1-3-33-22-13-20-17(12-21(22)30-23(32)9-7-16-5-4-10-31(16)2)24(28-14-27-20)29-15-6-8-19(26)18(25)11-15/h6-9,11-14,16H,3-5,10H2,1-2H3,(H,30,32)(H,27,28,29)/b9-7+/t16-/m1/s1	JZQOPZNZLUYLTR-MNDMWVCDSA-N	139994	US8901140, 9::US9358227, 9	Epidermal growth factor receptor	Homo sapiens		 2							US Patent		10.7270/Q2RJ4HB5		aid1802919	US9358227	Li, X; Wang, B	6/7/2016	6/12/2017	Jiangsu Hengrui Medicine Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139994&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			51039044	250184298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406573	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens		 92300					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406574	Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1	InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-	WUWDLXZGHZSWQZ-WQLSENKSSA-N	4810	(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one::CHEMBL276711::SU5146::SU5416::Semaxanib::US10189853, semaxanib::US11111252, Compound SU5416::US9422297, SU5416::cid_5329098	Epidermal growth factor receptor	Homo sapiens		 16600					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	X2M	2X2M	5329098	8034458		CHEMBL276711		5056		ZINC12410091	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406576	COc1cc2ncnc(Nc3ccc(NC(C)=O)cc3)c2cc1OC	InChI=1S/C18H18N4O3/c1-11(23)21-12-4-6-13(7-5-12)22-18-14-8-16(24-2)17(25-3)9-15(14)19-10-20-18/h4-10H,1-3H3,(H,21,23)(H,19,20,22)	VYDHNVNGKIOQFA-UHFFFAOYSA-N	50340921	CHEMBL1761927::N-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)acetamide::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}acetamide (11a)	Epidermal growth factor receptor	Homo sapiens		 31300					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50340921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50340921&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			7574840	131343857		CHEMBL1761927				ZINC05236337	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406578	CCN(CC)CCOc1cc2ncnc(Nc3ccc(NC(=O)OC)cc3)c2cc1OC	InChI=1S/C23H29N5O4/c1-5-28(6-2)11-12-32-21-14-19-18(13-20(21)30-3)22(25-15-24-19)26-16-7-9-17(10-8-16)27-23(29)31-4/h7-10,13-15H,5-6,11-12H2,1-4H3,(H,27,29)(H,24,25,26)	UJEJSEICUBNOQH-UHFFFAOYSA-N	233096	Methyl {4-[7-(2-diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}carbamate hydrochloride (7b)	Epidermal growth factor receptor	Homo sapiens		 1700					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010595	340093190							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406579	COC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1	InChI=1S/C18H18N4O4/c1-24-15-8-13-14(9-16(15)25-2)19-10-20-17(13)21-11-4-6-12(7-5-11)22-18(23)26-3/h4-10H,1-3H3,(H,22,23)(H,19,20,21)	HNEAOQOOUVUUJR-UHFFFAOYSA-N	50340923	CHEMBL1761929::Methyl {4-[6,7-dimethoxy-quinazolin-4-ylamino]phenyl}carbamate (11b)::methyl 4-(6,7-dimethoxyquinazolin-4-ylamino)phenylcarbamate	Epidermal growth factor receptor	Homo sapiens		 72400					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50340923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50340923&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			46209503	131343859		CHEMBL1761929				ZINC71318929	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406580	CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)OC)cc3)ncnc2cc1OC	InChI=1S/C23H29N5O4/c1-5-28(6-2)11-12-32-21-13-18-19(14-20(21)30-3)24-15-25-22(18)26-16-7-9-17(10-8-16)27-23(29)31-4/h7-10,13-15H,5-6,11-12H2,1-4H3,(H,27,29)(H,24,25,26)	ROMVXLKRJJOVQM-UHFFFAOYSA-N	233097	Methyl {4-[6-(2-diethylaminoethoxy)-7-methoxyquinazolin-4-ylamino]phenyl}carbamate hydrochloride (19b)	Epidermal growth factor receptor	Homo sapiens		 11100					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233097&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010596	340093191							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406581	CCOC(=O)Nc1ccc(Nc2ncnc3cc(OCCN(CC)CC)c(OC)cc23)cc1	InChI=1S/C24H31N5O4/c1-5-29(6-2)12-13-33-22-15-20-19(14-21(22)31-4)23(26-16-25-20)27-17-8-10-18(11-9-17)28-24(30)32-7-3/h8-11,14-16H,5-7,12-13H2,1-4H3,(H,28,30)(H,25,26,27)	SHLYCRFAVDOEGH-UHFFFAOYSA-N	233098	Ethyl {4-[7-(2-diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}carbamate hydrochloride (7c)	Epidermal growth factor receptor	Homo sapiens		 9400					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233098&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010597	340093192							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406582	CCOC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1	InChI=1S/C19H20N4O4/c1-4-27-19(24)23-13-7-5-12(6-8-13)22-18-14-9-16(25-2)17(26-3)10-15(14)20-11-21-18/h5-11H,4H2,1-3H3,(H,23,24)(H,20,21,22)	JVWYBRODEHTVBN-UHFFFAOYSA-N	50340925	CHEMBL1761931::Ethyl {4-[6,7-dimethoxy-quinazolin-4-ylamino]phenyl}carbamate (11c)::ethyl 4-(6,7-dimethoxyquinazolin-4-ylamino)phenylcarbamate	Epidermal growth factor receptor	Homo sapiens		 47900					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50340925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50340925&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54587267	131343861		CHEMBL1761931				ZINC71296477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406583	CCOC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OCCN(CC)CC)cc23)cc1	InChI=1S/C24H31N5O4/c1-5-29(6-2)12-13-33-22-14-19-20(15-21(22)31-4)25-16-26-23(19)27-17-8-10-18(11-9-17)28-24(30)32-7-3/h8-11,14-16H,5-7,12-13H2,1-4H3,(H,28,30)(H,25,26,27)	JUPRCVNZWMPUFI-UHFFFAOYSA-N	233099	Ethyl {4-[7-(2-diethylaminoethoxy)-6-methoxyquinazolin-4-ylamino]phenyl}carbamate hydrochloride (19c)	Epidermal growth factor receptor	Homo sapiens		 18600					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233099&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010598	340093193							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406584	CCN(CC)CCOc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccccc4)cc3)c2cc1OC	InChI=1S/C28H32N6O3/c1-4-34(5-2)15-16-37-26-18-24-23(17-25(26)36-3)27(30-19-29-24)31-21-11-13-22(14-12-21)33-28(35)32-20-9-7-6-8-10-20/h6-14,17-19H,4-5,15-16H2,1-3H3,(H,29,30,31)(H2,32,33,35)	VIMLYVOLENHMAR-UHFFFAOYSA-N	233100	N-{4-[7-(2-Diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-phenylurea hydrochloride (7d)	Epidermal growth factor receptor	Homo sapiens		 9100					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233100&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010599	340093194							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406585	COc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccccc4)cc3)c2cc1OC	InChI=1S/C23H21N5O3/c1-30-20-12-18-19(13-21(20)31-2)24-14-25-22(18)26-16-8-10-17(11-9-16)28-23(29)27-15-6-4-3-5-7-15/h3-14H,1-2H3,(H,24,25,26)(H2,27,28,29)	HRWOOOCQADOZGY-UHFFFAOYSA-N	50340927	1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-phenylurea::CHEMBL1761933::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N&#39;-phenylurea (11d)	Epidermal growth factor receptor	Homo sapiens		 28700					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50340927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50340927&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			46209504	131343863		CHEMBL1761933				ZINC71316366	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406586	CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)Nc4ccccc4)cc3)ncnc2cc1OC	InChI=1S/C28H32N6O3/c1-4-34(5-2)15-16-37-26-17-23-24(18-25(26)36-3)29-19-30-27(23)31-21-11-13-22(14-12-21)33-28(35)32-20-9-7-6-8-10-20/h6-14,17-19H,4-5,15-16H2,1-3H3,(H,29,30,31)(H2,32,33,35)	OYEPTZVAPJDGOW-UHFFFAOYSA-N	233101	N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-phenylurea hydrochloride (19d)	Epidermal growth factor receptor	Homo sapiens		 4300					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233101&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010600	340093195							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406587	CCN(CC)CCOc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccc(OC)cc4)cc3)c2cc1OC	InChI=1S/C29H34N6O4/c1-5-35(6-2)15-16-39-27-18-25-24(17-26(27)38-4)28(31-19-30-25)32-20-7-9-21(10-8-20)33-29(36)34-22-11-13-23(37-3)14-12-22/h7-14,17-19H,5-6,15-16H2,1-4H3,(H,30,31,32)(H2,33,34,36)	PGJBYKDTBCDEOE-UHFFFAOYSA-N	233102	N-{4-[7-(2-Diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(4-methoxy phenyl)urea hydrochloride (7e)	Epidermal growth factor receptor	Homo sapiens		 17100					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233102&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010601	340093196							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406588	COc1ccc(NC(=O)Nc2ccc(Nc3ncnc4cc(OC)c(OC)cc34)cc2)cc1	InChI=1S/C24H23N5O4/c1-31-18-10-8-17(9-11-18)29-24(30)28-16-6-4-15(5-7-16)27-23-19-12-21(32-2)22(33-3)13-20(19)25-14-26-23/h4-14H,1-3H3,(H,25,26,27)(H2,28,29,30)	XENAFWVEGOOYMA-UHFFFAOYSA-N	50340930	1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-(4-methoxyphenyl)urea::CHEMBL1761934::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(4-methoxyphenyl)urea (11e)	Epidermal growth factor receptor	Homo sapiens		 34500					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50340930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50340930&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54585296	131343866		CHEMBL1761934				ZINC71316000	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406589	CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)Nc4ccc(OC)cc4)cc3)ncnc2cc1OC	InChI=1S/C29H34N6O4/c1-5-35(6-2)15-16-39-27-17-24-25(18-26(27)38-4)30-19-31-28(24)32-20-7-9-21(10-8-20)33-29(36)34-22-11-13-23(37-3)14-12-22/h7-14,17-19H,5-6,15-16H2,1-4H3,(H,30,31,32)(H2,33,34,36)	HSELEVMNQQKQEM-UHFFFAOYSA-N	233103	N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(4-methoxy phenyl)urea hydrochloride (19e)	Epidermal growth factor receptor	Homo sapiens		 21500					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233103&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010602	340093197							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406590	CCN(CC)CCOc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccc(F)cc4F)cc3)c2cc1OC	InChI=1S/C28H30F2N6O3/c1-4-36(5-2)12-13-39-26-16-24-21(15-25(26)38-3)27(32-17-31-24)33-19-7-9-20(10-8-19)34-28(37)35-23-11-6-18(29)14-22(23)30/h6-11,14-17H,4-5,12-13H2,1-3H3,(H,31,32,33)(H2,34,35,37)	UKKWLRXCWWCNJY-UHFFFAOYSA-N	233104	N-{4-[7-(2-Diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(2,4-difluoro phenyl)urea hydrochloride (7f)	Epidermal growth factor receptor	Homo sapiens		 8300					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233104&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010603	340093198							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406591	COc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccc(F)cc4F)cc3)c2cc1OC	InChI=1S/C23H19F2N5O3/c1-32-20-10-16-19(11-21(20)33-2)26-12-27-22(16)28-14-4-6-15(7-5-14)29-23(31)30-18-8-3-13(24)9-17(18)25/h3-12H,1-2H3,(H,26,27,28)(H2,29,30,31)	SIBBDCDYYYTSNN-UHFFFAOYSA-N	233105	N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(2,4-difluorophenyl)urea (11f)	Epidermal growth factor receptor	Homo sapiens		 2100					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233105&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			46209505	340093199							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406592	CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)Nc4ccc(F)cc4F)cc3)ncnc2cc1OC	InChI=1S/C28H30F2N6O3/c1-4-36(5-2)12-13-39-26-15-21-24(16-25(26)38-3)31-17-32-27(21)33-19-7-9-20(10-8-19)34-28(37)35-23-11-6-18(29)14-22(23)30/h6-11,14-17H,4-5,12-13H2,1-3H3,(H,31,32,33)(H2,34,35,37)	NWEIIIQUESAORW-UHFFFAOYSA-N	233106	N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(2,4-difluoro phenyl)urea hydrochloride (19f)	Epidermal growth factor receptor	Homo sapiens		 1700					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233106&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010604	340093200							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406593	CCN(CC)CCOc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccc(F)c(Cl)c4)cc3)c2cc1OC	InChI=1S/C28H30ClFN6O3/c1-4-36(5-2)12-13-39-26-16-24-21(15-25(26)38-3)27(32-17-31-24)33-18-6-8-19(9-7-18)34-28(37)35-20-10-11-23(30)22(29)14-20/h6-11,14-17H,4-5,12-13H2,1-3H3,(H,31,32,33)(H2,34,35,37)	UJAKSNDFLVIHGT-UHFFFAOYSA-N	233107	N-{4-[7-(2-Diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(3-chloro-4-fluorophenyl)urea hydrochloride (7g)	Epidermal growth factor receptor	Homo sapiens		 43200					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233107&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010605	340093201							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406594	COc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccc(F)c(Cl)c4)cc3)c2cc1OC	InChI=1S/C23H19ClFN5O3/c1-32-20-10-16-19(11-21(20)33-2)26-12-27-22(16)28-13-3-5-14(6-4-13)29-23(31)30-15-7-8-18(25)17(24)9-15/h3-12H,1-2H3,(H,26,27,28)(H2,29,30,31)	WZLMBXUNTQCPJE-UHFFFAOYSA-N	50340944	1-(3-chloro-4-fluorophenyl)-3-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)urea::CHEMBL1761944::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(3-chloro-4-fluorophenyl)urea (11g)	Epidermal growth factor receptor	Homo sapiens		 15200					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50340944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50340944&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			54581370	131343880		CHEMBL1761944				ZINC71329939	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406595	CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)Nc4ccc(F)c(Cl)c4)cc3)ncnc2cc1OC	InChI=1S/C28H30ClFN6O3/c1-4-36(5-2)12-13-39-26-15-21-24(16-25(26)38-3)31-17-32-27(21)33-18-6-8-19(9-7-18)34-28(37)35-20-10-11-23(30)22(29)14-20/h6-11,14-17H,4-5,12-13H2,1-3H3,(H,31,32,33)(H2,34,35,37)	UYOIMRQPVGPJCF-UHFFFAOYSA-N	233108	N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-(3-chloro-4-fluorophenyl)urea hydrochloride (19g)	Epidermal growth factor receptor	Homo sapiens		 29200					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233108&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010606	340093202							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406596	CCCCNC(=O)Nc1ccc(Nc2ncnc3cc(OCCN(CC)CC)c(OC)cc23)cc1	InChI=1S/C26H36N6O3/c1-5-8-13-27-26(33)31-20-11-9-19(10-12-20)30-25-21-16-23(34-4)24(17-22(21)28-18-29-25)35-15-14-32(6-2)7-3/h9-12,16-18H,5-8,13-15H2,1-4H3,(H2,27,31,33)(H,28,29,30)	MOFPQQBOMHDLLE-UHFFFAOYSA-N	233109	N-{4-[7-(2-Diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-butylurea hydrochloride (7h)	Epidermal growth factor receptor	Homo sapiens		 5200					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233109&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010607	340093203							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406597	CCCCNC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1	InChI=1S/C21H25N5O3/c1-4-5-10-22-21(27)26-15-8-6-14(7-9-15)25-20-16-11-18(28-2)19(29-3)12-17(16)23-13-24-20/h6-9,11-13H,4-5,10H2,1-3H3,(H2,22,26,27)(H,23,24,25)	ZXRPRSOBABQJOG-UHFFFAOYSA-N	50380468	CHEMBL2018763::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N&#39;-butylurea (11h)	Epidermal growth factor receptor	Homo sapiens		 30600					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380468&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70687611	160859551		CHEMBL2018763				ZINC84633135	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406598	CCCCNC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OCCN(CC)CC)cc23)cc1	InChI=1S/C26H36N6O3/c1-5-8-13-27-26(33)31-20-11-9-19(10-12-20)30-25-21-16-24(35-15-14-32(6-2)7-3)23(34-4)17-22(21)28-18-29-25/h9-12,16-18H,5-8,13-15H2,1-4H3,(H2,27,31,33)(H,28,29,30)	WSHVKPNXWGOOIN-UHFFFAOYSA-N	233110	N-{4-[6-(2-Diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-butylurea hydrochloride (19h)	Epidermal growth factor receptor	Homo sapiens		 3400					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233110&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010608	340093204							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406599	CCNC(=O)Nc1ccc(Nc2ncnc3cc(OCCN(CC)CC)c(OC)cc23)cc1	InChI=1S/C24H32N6O3/c1-5-25-24(31)29-18-10-8-17(9-11-18)28-23-19-14-21(32-4)22(15-20(19)26-16-27-23)33-13-12-30(6-2)7-3/h8-11,14-16H,5-7,12-13H2,1-4H3,(H2,25,29,31)(H,26,27,28)	OPURPEXJKOYZRK-UHFFFAOYSA-N	50380447	CHEMBL2018772::N-{4-[7-(2-Diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}-N&#39;-ethylurea hydrochloride (7i)	Epidermal growth factor receptor	Homo sapiens		 29100					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56954328	160859530		CHEMBL2018772				ZINC84636087	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406600	CCNC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1	InChI=1S/C19H21N5O3/c1-4-20-19(25)24-13-7-5-12(6-8-13)23-18-14-9-16(26-2)17(27-3)10-15(14)21-11-22-18/h5-11H,4H2,1-3H3,(H2,20,24,25)(H,21,22,23)	YNCKOZXQTQUWHF-UHFFFAOYSA-N	50380467	CHEMBL2016600::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N&#39;-ethylurea (11i)	Epidermal growth factor receptor	Homo sapiens		 36300					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380467&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56954232	160859550		CHEMBL2016600				ZINC84633133	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406602	CCN(CC)CCOc1cc2ncnc(Nc3ccc(NC(=O)NC4CCCCC4)cc3)c2cc1OC	InChI=1S/C28H38N6O3/c1-4-34(5-2)15-16-37-26-18-24-23(17-25(26)36-3)27(30-19-29-24)31-21-11-13-22(14-12-21)33-28(35)32-20-9-7-6-8-10-20/h11-14,17-20H,4-10,15-16H2,1-3H3,(H,29,30,31)(H2,32,33,35)	GRHPWBWINCJUFI-UHFFFAOYSA-N	233112	N-Cyclohexyl-N&#39;-{4-[7-(2-diethylaminoethoxy)-6-methoxy-quinazolin-4-ylamino]phenyl}urea hydrochloride (7j)	Epidermal growth factor receptor	Homo sapiens		 28200					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233112&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010610	340093206							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406603	COc1cc2ncnc(Nc3ccc(NC(=O)NC4CCCCC4)cc3)c2cc1OC	InChI=1S/C23H27N5O3/c1-30-20-12-18-19(13-21(20)31-2)24-14-25-22(18)26-16-8-10-17(11-9-16)28-23(29)27-15-6-4-3-5-7-15/h8-15H,3-7H2,1-2H3,(H,24,25,26)(H2,27,28,29)	MWAKSHNGTXXSDD-UHFFFAOYSA-N	233113	N-Cyclohexyl-N&#39;-{4-[6,7-dimethoxy-quinazolin-4-ylamino]phenyl}urea (11j)	Epidermal growth factor receptor	Homo sapiens		 51300					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233113&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010611	340093207							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
406604	CCN(CC)CCOc1cc2c(Nc3ccc(NC(=O)NC4CCCCC4)cc3)ncnc2cc1OC	InChI=1S/C28H38N6O3/c1-4-34(5-2)15-16-37-26-17-23-24(18-25(26)36-3)29-19-30-27(23)31-21-11-13-22(14-12-21)33-28(35)32-20-9-7-6-8-10-20/h11-14,17-20H,4-10,15-16H2,1-3H3,(H,29,30,31)(H2,32,33,35)	LXOCUJRACFRTGF-UHFFFAOYSA-N	233114	N-Cyclohexyl-N&#39;-{4-[6-(2-diethylaminoethoxy)-7-methoxy-quinazolin-4-ylamino]phenyl}urea hydrochloride (19j)	Epidermal growth factor receptor	Homo sapiens		 32300					7.5		Curated from the literature by BindingDB	10.3109/14756360903169485	10.7270/Q2Z31XJ2	20222760	aid1802936		Garofalo, A; Goossens, L; Lemoine, A; Farce, A; Arlot, Y; Depreux, P	4/28/2010	6/15/2017	Université Lille Nord de France	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233114&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129010612	340093208							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
408581	OC[C@H]1OC([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc2oc3cc(O)c(O)cc3c(=O)c2c1O	InChI=1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19?/m1/s1	AEDDIBAIWPIIBD-JGPIWLIHSA-N	234389	Mangiferin	Epidermal growth factor receptor	Homo sapiens		>1.0e+4					7		Curated from the literature by BindingDB	10.3109/14756366.2010.515215	10.7270/Q2S46QTV	20846091	aid1802992		Han, SY; Chin, YW	6/28/2011	6/23/2017	Gyeongsang National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			5464041	340094378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
412016	Nc1ccc(cn1)-c1ccc2ncc3c(n(-c4cccc(c4)C(F)(F)F)c(=O)[nH]c3=O)c2n1	InChI=1S/C22H13F3N6O2/c23-22(24,25)12-2-1-3-13(8-12)31-19-14(20(32)30-21(31)33)10-27-16-6-5-15(29-18(16)19)11-4-7-17(26)28-9-11/h1-10H,(H2,26,28)(H,30,32,33)	OIOOKLQHEDGJOE-UHFFFAOYSA-N	236557	US9365572, 5	Epidermal growth factor receptor	Homo sapiens		>10000					7.5	28.00 C	US Patent		10.7270/Q20C4TNC		aid1803088	US9365572	Wu, F; Shu, C	6/14/2016	7/10/2017	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=236557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=236557&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129012341	340130144							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
415922	Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1NC(=O)c1cccc2c(N)nccc12	InChI=1S/C25H19F3N4O2/c1-14-8-9-17(31-23(33)15-4-2-5-16(12-15)25(26,27)28)13-21(14)32-24(34)20-7-3-6-19-18(20)10-11-30-22(19)29/h2-13H,1H3,(H2,29,30)(H,31,33)(H,32,34)	JETCTCUSGZDEGL-UHFFFAOYSA-N	238345	US9388165, 1	Epidermal growth factor receptor	Homo sapiens		>2500							US Patent		10.7270/Q2F76BF9		aid1803154	US9388165	Bae, IH; Han, SM; Kwak, EJ; Ahn, YG; Suh, KH	7/12/2016	7/17/2017	Hanmi Pharm. Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=238345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=238345&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118090792	340131706							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417230	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3)C2=O)c1	InChI=1S/C22H22O3/c1-24-20-13-17(14-21(15-20)25-2)12-19-10-6-9-18(22(19)23)11-16-7-4-3-5-8-16/h3-5,7-8,11-15H,6,9-10H2,1-2H3/b18-11+,19-12+	LQVXXMBNQOFZDU-GDAWTGGTSA-N	50424975	CHEMBL2316140::US9409845, Table 1, Compound 1: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-benzylidenecyclohexanone	Epidermal growth factor receptor	Homo sapiens		 1680						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424975&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508607	164153850		CHEMBL2316140				ZINC95597686	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417231	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cccc(Cl)c3)C2=O)c1	InChI=1S/C22H21ClO3/c1-25-20-12-16(13-21(14-20)26-2)10-18-7-4-6-17(22(18)24)9-15-5-3-8-19(23)11-15/h3,5,8-14H,4,6-7H2,1-2H3/b17-9+,18-10+	QPQXKYPXOWABMC-BEQMOXJMSA-N	50424974	CHEMBL2316141::US9409845, Table 1, Compound 2: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(3-chlorobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 2270						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424974&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508608	164153849		CHEMBL2316141				ZINC95596941	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417232	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3Cl)C2=O)c1	InChI=1S/C22H21ClO3/c1-25-19-11-15(12-20(14-19)26-2)10-17-7-5-8-18(22(17)24)13-16-6-3-4-9-21(16)23/h3-4,6,9-14H,5,7-8H2,1-2H3/b17-10+,18-13+	HTECUFCXSIPTNC-YAUBYZHOSA-N	50424973	CHEMBL2316142::US9409845, Table 1, Compound 3: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(2-chlorobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 1540						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424973	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424973&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508609	164153848		CHEMBL2316142				ZINC95598080	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417233	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3F)C2=O)c1	InChI=1S/C22H21FO3/c1-25-19-11-15(12-20(14-19)26-2)10-17-7-5-8-18(22(17)24)13-16-6-3-4-9-21(16)23/h3-4,6,9-14H,5,7-8H2,1-2H3/b17-10+,18-13+	CLEKNGMKRNGHMK-YAUBYZHOSA-N	50424972	CHEMBL2316143::US9409845, Table 1, Compound 4: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(2-fluorobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 2170						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424972&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508610	164153847		CHEMBL2316143				ZINC95593603	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417234	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3Br)C2=O)c1	InChI=1S/C22H21BrO3/c1-25-19-11-15(12-20(14-19)26-2)10-17-7-5-8-18(22(17)24)13-16-6-3-4-9-21(16)23/h3-4,6,9-14H,5,7-8H2,1-2H3/b17-10+,18-13+	HQTAAPOMNNDGNN-YAUBYZHOSA-N	50424971	CHEMBL2316144::US9409845, Table 1, Compound 5: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(2-bromobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 8080						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424971&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508643	164153846		CHEMBL2316144				ZINC95594788	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417235	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cccc(Br)c3)C2=O)c1	InChI=1S/C22H21BrO3/c1-25-20-12-16(13-21(14-20)26-2)10-18-7-4-6-17(22(18)24)9-15-5-3-8-19(23)11-15/h3,5,8-14H,4,6-7H2,1-2H3/b17-9+,18-10+	HBSBXUHFMSIYDK-BEQMOXJMSA-N	50424970	CHEMBL2316145::US9409845, Table 1, Compound 6: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(3-bromobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 6850						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424970	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424970&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508644	164153845		CHEMBL2316145				ZINC95596922	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417236	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(Br)cc3)C2=O)c1	InChI=1S/C22H21BrO3/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14H,3-5H2,1-2H3/b17-10+,18-11+	VALHLOXXMQSXQS-ODPUSEOTSA-N	50424969	CHEMBL2316146::US9409845, Table 1, Compound 7: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-bromobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 7120						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424969	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424969&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508645	164153844		CHEMBL2316146				ZINC95597192	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417237	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(F)cc3)C2=O)c1	InChI=1S/C22H21FO3/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14H,3-5H2,1-2H3/b17-10+,18-11+	LMIYBACSMMOBLU-ODPUSEOTSA-N	50424968	CHEMBL2316147::US9409845, Table 1, Compound 8: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-fluorobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 5690						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424968&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508646	164153843		CHEMBL2316147				ZINC95594322	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417238	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(Cl)cc3)C2=O)c1	InChI=1S/C22H21ClO3/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14H,3-5H2,1-2H3/b17-10+,18-11+	YTJPZUZXESULTP-ODPUSEOTSA-N	50424967	CHEMBL2316148::US9409845, Table 1, Compound 9: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-chlorobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 15320						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424967	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424967&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508647	164153842		CHEMBL2316148				ZINC95596019	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417239	COc1cc(OC)cc(\C=C2/CCC\C(=C/C3CCCCC3)C2=O)c1	InChI=1S/C22H28O3/c1-24-20-13-17(14-21(15-20)25-2)12-19-10-6-9-18(22(19)23)11-16-7-4-3-5-8-16/h11-16H,3-10H2,1-2H3/b18-11+,19-12+	YCAWKDCGUHXZFV-GDAWTGGTSA-N	50424966	CHEMBL2316149::US9409845, Table 1, Compound 10: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(cyclohexylmethylene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 7520						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424966&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508648	164153841		CHEMBL2316149				ZINC95596914	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417240	COc1cccc(\C=C2/CCC\C(=C/c3cc(OC)cc(OC)c3)C2=O)c1	InChI=1S/C23H24O4/c1-25-20-9-4-6-16(12-20)10-18-7-5-8-19(23(18)24)11-17-13-21(26-2)15-22(14-17)27-3/h4,6,9-15H,5,7-8H2,1-3H3/b18-10+,19-11+	NAAUBJFDXWTYOS-XOBNHNQQSA-N	50424965	CHEMBL2316150::US9409845, Table 1, Compound 11: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(3-methoxybenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 6130						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424965&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508649	164153840		CHEMBL2316150				ZINC95597044	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417241	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(O)c(O)c3)C2=O)c1	InChI=1S/C22H22O5/c1-26-18-10-15(11-19(13-18)27-2)9-17-5-3-4-16(22(17)25)8-14-6-7-20(23)21(24)12-14/h6-13,23-24H,3-5H2,1-2H3/b16-8+,17-9+	NXLXNLATMMPUNC-GONBZBRSSA-N	50424964	CHEMBL2316151::US9409845, Table 1, Compound 12: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(3,4-dihydroxybenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 430						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424964&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508689	164153839		CHEMBL2316151				ZINC95595581	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417242	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3OC)C2=O)c1	InChI=1S/C23H24O4/c1-25-20-12-16(13-21(15-20)26-2)11-18-8-6-9-19(23(18)24)14-17-7-4-5-10-22(17)27-3/h4-5,7,10-15H,6,8-9H2,1-3H3/b18-11+,19-14+	UFXSXKGMRKSRAK-MMOYSQFZSA-N	50424963	CHEMBL2316152::US9409845, Table 1, Compound 13: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(2-methoxybenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 20890						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424963	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424963&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508690	164153838		CHEMBL2316152				ZINC95593662	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417243	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(O)cc3)C2=O)c1	InChI=1S/C22H22O4/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14,23H,3-5H2,1-2H3/b17-10+,18-11+	AGMCEFOYMFDQNT-ODPUSEOTSA-N	50424962	CHEMBL2316153::US9409845, Table 1, Compound 14: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-hydrobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 4660						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424962&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508691	164153837		CHEMBL2316153				ZINC95597217	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417244	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(cc3)N(C)C)C2=O)c1	InChI=1S/C24H27NO3/c1-25(2)21-10-8-17(9-11-21)12-19-6-5-7-20(24(19)26)13-18-14-22(27-3)16-23(15-18)28-4/h8-16H,5-7H2,1-4H3/b19-12+,20-13+	MTWBBTPEPAYVAA-KVOOEGMKSA-N	50424961	CHEMBL2316154::US9409845, Table 1, Compound 15: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-dimethylaminobenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 3980						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424961&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508692	164153836		CHEMBL2316154				ZINC95597230	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417245	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(OC)c(O)c3)C2=O)c1	InChI=1S/C23H24O5/c1-26-19-11-16(12-20(14-19)27-2)10-18-6-4-5-17(23(18)25)9-15-7-8-22(28-3)21(24)13-15/h7-14,24H,4-6H2,1-3H3/b17-9+,18-10+	CNMLPAQHCYHPBA-BEQMOXJMSA-N	50424960	CHEMBL2316155::US9409845, Table 1, Compound 16: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(3-hydroxyl-4-methoxybenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 5370						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424960	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424960&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508693	164153835		CHEMBL2316155				ZINC95597487	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417246	COc1cc(OC)cc(\C=C2/CCCCC2=O)c1	InChI=1S/C15H18O3/c1-17-13-8-11(9-14(10-13)18-2)7-12-5-3-4-6-15(12)16/h7-10H,3-6H2,1-2H3/b12-7+	NQSNEFRNBFRJBE-KPKJPENVSA-N	239058	US9409845, Table 1, Compound 17: (2E,6E)-2-di-(3,5-dimethoxybenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 18670						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239058&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129012636	340132346							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417247	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cc(OC)cc(OC)c3)C2=O)c1	InChI=1S/C24H26O5/c1-26-20-10-16(11-21(14-20)27-2)8-18-6-5-7-19(24(18)25)9-17-12-22(28-3)15-23(13-17)29-4/h8-15H,5-7H2,1-4H3/b18-8+,19-9+	LCTMHSXNDBNPAF-GCBPPVMSSA-N	50424958	CHEMBL2316157::US9409845, Table 1, Compound 18: (2E,6E)-2,6-(3,5-dimethoxybenzylidene)-6-(3,5-dimethoxybenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 2080						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424958&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508695	164153833		CHEMBL2316157				ZINC95598275	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417248	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(cc3)S(C)(=O)=O)C2=O)c1	InChI=1S/C23H24O5S/c1-27-20-13-17(14-21(15-20)28-2)12-19-6-4-5-18(23(19)24)11-16-7-9-22(10-8-16)29(3,25)26/h7-15H,4-6H2,1-3H3/b18-11+,19-12+	KCKFFUAUNCDZHZ-GDAWTGGTSA-N	50424957	CHEMBL2316158::US9409845, Table 1, Compound 19: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-methylsulphonylbenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 1960						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424957&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508717	164153832		CHEMBL2316158				ZINC95598122	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417249	COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C)C2=O)c1	InChI=1S/C30H38O4/c1-29(2,3)25-16-20(17-26(28(25)32)30(4,5)6)13-22-11-9-10-21(27(22)31)12-19-14-23(33-7)18-24(15-19)34-8/h12-18,32H,9-11H2,1-8H3/b21-12+,22-13+	SNYZTPOUJHDPAX-ADYPVIEZSA-N	50424956	CHEMBL2316159::US9409845, Table 1, Compound 20: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(3,5-di-tert-butyl -4-hydroxybenzylidene)cyclohexanone	Epidermal growth factor receptor	Homo sapiens		 4810						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424956&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71508718	164153831		CHEMBL2316159				ZINC95593702	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417250	COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O	InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+	VFLDPWHFBUODDF-FCXRPNKRSA-N	50140172	CHEBI:3962::CHEMBL140::Curcumin::US9409845, Table 1, Compound 21: curcumin	Epidermal growth factor receptor	Homo sapiens		 8650						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140172&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	CC9	6HDR	969516	336952476		CHEMBL140					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
417251	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens		 30						25.00 C	US Patent		10.7270/Q25M64MC		aid1803203	US9409845	Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S	8/9/2016	7/24/2017	PHARMAXYN LABORATORIES LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
421748	Nc1c(c(nn1-c1c(Cl)cc(Cl)cc1Cl)-c1ccncc1)-c1ccc(F)cc1	InChI=1S/C20H12Cl3FN4/c21-13-9-15(22)19(16(23)10-13)28-20(25)17(11-1-3-14(24)4-2-11)18(27-28)12-5-7-26-8-6-12/h1-10H,25H2	MOHYPRXHKRXDSE-UHFFFAOYSA-N	50379214	CHEMBL2011291::US9416123, 6	Epidermal growth factor receptor	Homo sapiens		 110					7.5	30.00 C	US Patent		10.7270/Q2V123PP		aid1803274	US9416123	Burnet, MW; Thaher, BA; Ehlert, J; Kubbutat, M; Schaechtele, C; Totzke, F	8/16/2016	8/7/2017	Synovo GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50379214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50379214&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56924694	160858297		CHEMBL2011291				ZINC84604180	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
421755	Nc1c(c(nn1-c1c(Cl)cc(Cl)cc1Cl)-c1ccncc1)-c1ccc(F)cc1	InChI=1S/C20H12Cl3FN4/c21-13-9-15(22)19(16(23)10-13)28-20(25)17(11-1-3-14(24)4-2-11)18(27-28)12-5-7-26-8-6-12/h1-10H,25H2	MOHYPRXHKRXDSE-UHFFFAOYSA-N	50379214	CHEMBL2011291::US9416123, 6	Epidermal growth factor receptor	Homo sapiens		 50					7.5	30.00 C	US Patent		10.7270/Q2V123PP		aid1803274	US9416123	Burnet, MW; Thaher, BA; Ehlert, J; Kubbutat, M; Schaechtele, C; Totzke, F	8/16/2016	8/7/2017	Synovo GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50379214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50379214&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56924694	160858297		CHEMBL2011291				ZINC84604180	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
421765	Nc1c(c(nn1-c1c(Cl)cc(Cl)cc1Cl)-c1ccncc1)-c1ccc(F)cc1	InChI=1S/C20H12Cl3FN4/c21-13-9-15(22)19(16(23)10-13)28-20(25)17(11-1-3-14(24)4-2-11)18(27-28)12-5-7-26-8-6-12/h1-10H,25H2	MOHYPRXHKRXDSE-UHFFFAOYSA-N	50379214	CHEMBL2011291::US9416123, 6	Epidermal growth factor receptor	Homo sapiens		 210					7.5	30.00 C	US Patent		10.7270/Q2V123PP		aid1803274	US9416123	Burnet, MW; Thaher, BA; Ehlert, J; Kubbutat, M; Schaechtele, C; Totzke, F	8/16/2016	8/7/2017	Synovo GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50379214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50379214&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56924694	160858297		CHEMBL2011291				ZINC84604180	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
421771	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens		 1.4					7.5	30.00 C	US Patent		10.7270/Q2V123PP		aid1803274	US9416123	Burnet, MW; Thaher, BA; Ehlert, J; Kubbutat, M; Schaechtele, C; Totzke, F	8/16/2016	8/7/2017	Synovo GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
421781	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens		 3					7.5	30.00 C	US Patent		10.7270/Q2V123PP		aid1803274	US9416123	Burnet, MW; Thaher, BA; Ehlert, J; Kubbutat, M; Schaechtele, C; Totzke, F	8/16/2016	8/7/2017	Synovo GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423186	Nc1nc(N)c2c(n1)[nH]c1cccc(Sc3ccccc3)c21	InChI=1S/C16H13N5S/c17-14-13-12-10(19-15(13)21-16(18)20-14)7-4-8-11(12)22-9-5-2-1-3-6-9/h1-8H,(H5,17,18,19,20,21)	DXZCXZCCPLYVDG-UHFFFAOYSA-N	50314076	5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamine::CHEMBL1093099::US9422297, AAG-148-43	Epidermal growth factor receptor	Homo sapiens		 15070							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314076&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25181586	104148437		CHEMBL1093099				ZINC49072435	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423199	CC(C)c1ccccc1Nc1nc(N)nc2Cc3ccccc3-c12	InChI=1S/C20H20N4/c1-12(2)14-8-5-6-10-16(14)22-19-18-15-9-4-3-7-13(15)11-17(18)23-20(21)24-19/h3-10,12H,11H2,1-2H3,(H3,21,22,23,24)	DFMQLARCVPAGSC-UHFFFAOYSA-N	242722	US9422297, AAG145-124 	Epidermal growth factor receptor	Homo sapiens		>200000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242722&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218331	341094862							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423200	CC(C)c1ccc(Nc2nc(N)nc3Cc4ccccc4-c23)cc1	InChI=1S/C20H20N4/c1-12(2)13-7-9-15(10-8-13)22-19-18-16-6-4-3-5-14(16)11-17(18)23-20(21)24-19/h3-10,12H,11H2,1-2H3,(H3,21,22,23,24)	PUPIDEKMUKQDBG-UHFFFAOYSA-N	242723	US9422297, AAG145-126 	Epidermal growth factor receptor	Homo sapiens		 42600							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242723&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218332	341094863							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423201	Nc1nc2Cc3ccccc3-c2c(Nc2cccc(Br)c2)n1	InChI=1S/C17H13BrN4/c18-11-5-3-6-12(9-11)20-16-15-13-7-2-1-4-10(13)8-14(15)21-17(19)22-16/h1-7,9H,8H2,(H3,19,20,21,22)	QVKUVEHRSYCMGZ-UHFFFAOYSA-N	242724	US9422297, AAG145-131 	Epidermal growth factor receptor	Homo sapiens		 24100							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242724&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218335	341094864							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423202	Nc1nc2Cc3ccccc3-c2c(Nc2ccc(Cl)cc2F)n1	InChI=1S/C17H12ClFN4/c18-10-5-6-13(12(19)8-10)21-16-15-11-4-2-1-3-9(11)7-14(15)22-17(20)23-16/h1-6,8H,7H2,(H3,20,21,22,23)	WHCQIGNZIYEVMT-UHFFFAOYSA-N	242725	US9422297, AAG145-135 	Epidermal growth factor receptor	Homo sapiens		 11700							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242725&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25216477	341094865							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423203	Nc1nc2Cc3ccccc3-c2c(Nc2ccc(Cl)cc2)n1	InChI=1S/C17H13ClN4/c18-11-5-7-12(8-6-11)20-16-15-13-4-2-1-3-10(13)9-14(15)21-17(19)22-16/h1-8H,9H2,(H3,19,20,21,22)	PUNTVOFUMRATBV-UHFFFAOYSA-N	242726	US9422297, AAG145-136 	Epidermal growth factor receptor	Homo sapiens		 26000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242726&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218337	341094866							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423204	Nc1nc2Cc3ccccc3-c2c(Nc2cccc(Cl)c2)n1	InChI=1S/C17H13ClN4/c18-11-5-3-6-12(9-11)20-16-15-13-7-2-1-4-10(13)8-14(15)21-17(19)22-16/h1-7,9H,8H2,(H3,19,20,21,22)	OPZGHXBSYDRRLL-UHFFFAOYSA-N	242727	US9422297, AAG145-157 	Epidermal growth factor receptor	Homo sapiens		 19600							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242727&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218334	341094867							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423205	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC	InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)	LSPANGZZENHZNJ-UHFFFAOYSA-N	3032	CHEMBL1204168::CHEMBL29197::N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035::US11001595, Compound PD153035::US11111252, Compound PD153035::US9422297, PD153035	Epidermal growth factor receptor	Homo sapiens		 230							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=3032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=3032&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			4705	8032779		CHEMBL1204168CHEMBL29197				ZINC00600292	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423206	Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1	InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)	HTUBKQUPEREOGA-UHFFFAOYSA-N	4567	4-anilinoquinazoline deriv. 2::BMC163482 Compound 1::CHEMBL285063::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}prop-2-enamide::US9422297, PD168393	Epidermal growth factor receptor	Homo sapiens		 130							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4567&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	DJK	3LOK,4LQM,2J5F,2HWP	4708	8034230		CHEMBL285063	DB07662			ZINC01488208	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423207	Nc1nc2Cc3ccccc3-c2c(Nc2ccccc2)n1	InChI=1S/C17H14N4/c18-17-20-14-10-11-6-4-5-9-13(11)15(14)16(21-17)19-12-7-2-1-3-8-12/h1-9H,10H2,(H3,18,19,20,21)	BFUFGJUGGVINNF-UHFFFAOYSA-N	242728	US9422297, AAG145-158 	Epidermal growth factor receptor	Homo sapiens		>200000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242728&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218205	341094868							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423208	COc1cccc(Nc2nc(N)nc3Cc4ccccc4-c23)c1	InChI=1S/C18H16N4O/c1-23-13-7-4-6-12(10-13)20-17-16-14-8-3-2-5-11(14)9-15(16)21-18(19)22-17/h2-8,10H,9H2,1H3,(H3,19,20,21,22)	NLHWLKWHFRIZDW-UHFFFAOYSA-N	242729	US9422297, AAG145-159 	Epidermal growth factor receptor	Homo sapiens		>200000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242729&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25216475	341094869							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423209	Nc1nc2Cc3ccccc3-c2c(Nc2cccc(F)c2)n1	InChI=1S/C17H13FN4/c18-11-5-3-6-12(9-11)20-16-15-13-7-2-1-4-10(13)8-14(15)21-17(19)22-16/h1-7,9H,8H2,(H3,19,20,21,22)	JJUMBPJQWGPNKX-UHFFFAOYSA-N	242730	US9422297, AAG145-161 	Epidermal growth factor receptor	Homo sapiens		>200000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242730	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242730&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218333	341094870							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423210	Nc1nc2Cc3ccccc3-c2c(Nc2ccc(F)c(Cl)c2)n1	InChI=1S/C17H12ClFN4/c18-12-8-10(5-6-13(12)19)21-16-15-11-4-2-1-3-9(11)7-14(15)22-17(20)23-16/h1-6,8H,7H2,(H3,20,21,22,23)	GTLDVWXJAMGWRF-UHFFFAOYSA-N	242731	US9422297, AAG145-164 	Epidermal growth factor receptor	Homo sapiens		>200000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242731&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			25216476	341094871							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423233	Nc1nc-2c(Cc3ccccc-23)c(Nc2cccc(Cl)c2)n1	InChI=1S/C17H13ClN4/c18-11-5-3-6-12(9-11)20-16-14-8-10-4-1-2-7-13(10)15(14)21-17(19)22-16/h1-7,9H,8H2,(H3,19,20,21,22)	AGYWWJAKSWKVBH-UHFFFAOYSA-N	242721	US9422297, AAG145-335	Epidermal growth factor receptor	Homo sapiens		 45100							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242721&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129625872	341094861							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423234	Nc1nc-2c(Cc3ccccc-23)c(Nc2cccc(Br)c2)n1	InChI=1S/C17H13BrN4/c18-11-5-3-6-12(9-11)20-16-14-8-10-4-1-2-7-13(10)15(14)21-17(19)22-16/h1-7,9H,8H2,(H3,19,20,21,22)	GPZMBZBFURQTKV-UHFFFAOYSA-N	242732	US9422297, AAG155-336	Epidermal growth factor receptor	Homo sapiens		 98800							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242732&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129625873	341094872							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423235	Nc1nc-2c(Cc3ccccc-23)c(Nc2ccc(Cl)cc2)n1	InChI=1S/C17H13ClN4/c18-11-5-7-12(8-6-11)20-16-14-9-10-3-1-2-4-13(10)15(14)21-17(19)22-16/h1-8H,9H2,(H3,19,20,21,22)	IGJYYVYHPMKKRI-UHFFFAOYSA-N	242733	US9422297, AAG145-340	Epidermal growth factor receptor	Homo sapiens		>300000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242733&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129625874	341094873							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423236	Nc1nc-2c(Cc3ccccc-23)c(Nc2ccc(Br)cc2)n1	InChI=1S/C17H13BrN4/c18-11-5-7-12(8-6-11)20-16-14-9-10-3-1-2-4-13(10)15(14)21-17(19)22-16/h1-8H,9H2,(H3,19,20,21,22)	UQZHWHRWEYLJNU-UHFFFAOYSA-N	242734	US9422297, AAG145-341	Epidermal growth factor receptor	Homo sapiens		>300000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242734&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129625875	341094874							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423237	CC(C)c1ccccc1Nc1nc(N)nc-2c1Cc1ccccc-21	InChI=1S/C20H20N4/c1-12(2)14-8-5-6-10-17(14)22-19-16-11-13-7-3-4-9-15(13)18(16)23-20(21)24-19/h3-10,12H,11H2,1-2H3,(H3,21,22,23,24)	AVSIKJCSTGRHSG-UHFFFAOYSA-N	242735	US9422297, AAG145-342	Epidermal growth factor receptor	Homo sapiens		 23000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242735&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129625876	341094875							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423238	Nc1nc-2c(Cc3ccccc-23)c(Nc2ccccc2)n1	InChI=1S/C17H14N4/c18-17-20-15-13-9-5-4-6-11(13)10-14(15)16(21-17)19-12-7-2-1-3-8-12/h1-9H,10H2,(H3,18,19,20,21)	FPMKNIPEOGMYEG-UHFFFAOYSA-N	242736	US9422297, AAG145-344	Epidermal growth factor receptor	Homo sapiens		 232700							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242736&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57608010	341094876							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423239	Nc1nc-2c(Cc3ccccc-23)c(Nc2cccc(F)c2)n1	InChI=1S/C17H13FN4/c18-11-5-3-6-12(9-11)20-16-14-8-10-4-1-2-7-13(10)15(14)21-17(19)22-16/h1-7,9H,8H2,(H3,19,20,21,22)	XXBVCIPPGHKJAG-UHFFFAOYSA-N	242737	US9422297, AAG145-346	Epidermal growth factor receptor	Homo sapiens		>300000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242737&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129625877	341094877							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423240	Nc1nc-2c(Cc3ccccc-23)c(Nc2ccc(F)cc2)n1	InChI=1S/C17H13FN4/c18-11-5-7-12(8-6-11)20-16-14-9-10-3-1-2-4-13(10)15(14)21-17(19)22-16/h1-8H,9H2,(H3,19,20,21,22)	INMJXDOKKQDBSI-UHFFFAOYSA-N	242738	US9422297, AAG145-347	Epidermal growth factor receptor	Homo sapiens		>300000							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242738&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129625878	341094878							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
423241	Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1	InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)	HTUBKQUPEREOGA-UHFFFAOYSA-N	4567	4-anilinoquinazoline deriv. 2::BMC163482 Compound 1::CHEMBL285063::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}prop-2-enamide::US9422297, PD168393	Epidermal growth factor receptor	Homo sapiens		 521							US Patent		10.7270/Q2MC8XX9		aid1803310	US9422297	Gangjee, A	8/23/2016	8/14/2017	Duquesne University of the Holy Ghost	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4567&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	DJK	3LOK,4LQM,2J5F,2HWP	4708	8034230		CHEMBL285063	DB07662			ZINC01488208	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
430176	Fc1ccc(cc1)-c1cc([nH]c(=N)c1C#N)-c1ccc(Nc2ncnc3ccccc23)cc1	InChI=1S/C26H17FN6/c27-18-9-5-16(6-10-18)21-13-24(33-25(29)22(21)14-28)17-7-11-19(12-8-17)32-26-20-3-1-2-4-23(20)30-15-31-26/h1-13,15H,(H2,29,33)(H,30,31,32)	LUNPOMNMCATHCT-UHFFFAOYSA-N	246607	HER2/EGFR dual kinase inhibitor, 5d	Epidermal growth factor receptor	Homo sapiens		 2088							Curated from the literature by BindingDB	10.3109/14756366.2013.765417	10.7270/Q20C4TPT	23402383	aid1803399		Sadek, MM; Serrya, RA; Kafafy, AH; Ahmed, M; Wang, F; Abouzid, KA	4/28/2014	8/31/2017	MSA University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246607&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129627019	341104394							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
430177	COc1cc2ncnc(Nc3ccc(cc3)-c3cc(-c4ccc(Br)cc4)c(C#N)c(=N)[nH]3)c2cc1OC	InChI=1S/C28H21BrN6O2/c1-36-25-12-21-24(13-26(25)37-2)32-15-33-28(21)34-19-9-5-17(6-10-19)23-11-20(22(14-30)27(31)35-23)16-3-7-18(29)8-4-16/h3-13,15H,1-2H3,(H2,31,35)(H,32,33,34)	GVOPMIJWESGYMJ-UHFFFAOYSA-N	246608	4-{4-[6-(4-(4-Bromophenyl)-3-cyano-2-imino)-1,2-dihydropyridyl]phenylamino}6,7-dimethoxyquinazoline::HER2/EGFR dual kinase inhibitor, 5e	Epidermal growth factor receptor	Homo sapiens		 1935							Curated from the literature by BindingDB	10.3109/14756366.2013.765417	10.7270/Q20C4TPT	23402383	aid1803399		Sadek, MM; Serrya, RA; Kafafy, AH; Ahmed, M; Wang, F; Abouzid, KA	4/28/2014	8/31/2017	MSA University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246608&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129627020	341104395							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
430178	COc1cc2ncnc(Nc3ccc(cc3)C(=O)\C=C\c3ccc(Cl)cc3)c2cc1OC	InChI=1S/C25H20ClN3O3/c1-31-23-13-20-21(14-24(23)32-2)27-15-28-25(20)29-19-10-6-17(7-11-19)22(30)12-5-16-3-8-18(26)9-4-16/h3-15H,1-2H3,(H,27,28,29)/b12-5+	MIFKLWONDMFKNY-LFYBBSHMSA-N	246609	(E)-3-(4-Chlorophenyl)-1-{4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl}prop-2-en-1-one::HER2/EGFR dual kinase inhibitor, 7e	Epidermal growth factor receptor	Homo sapiens		 2582							Curated from the literature by BindingDB	10.3109/14756366.2013.765417	10.7270/Q20C4TPT	23402383	aid1803399		Sadek, MM; Serrya, RA; Kafafy, AH; Ahmed, M; Wang, F; Abouzid, KA	4/28/2014	8/31/2017	MSA University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246609&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			76900441	341104396							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
431424	NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F	InChI=1S/C20H24BrF2N5O3S/c21-12-9-14(22)13(15(23)10-12)11-31-18-16(17(24)29)19(32-27-18)26-20(30)25-5-1-2-6-28-7-3-4-8-28/h9-10H,1-8,11H2,(H2,24,29)(H2,25,26,30)	HXHAJRMTJXHJJZ-UHFFFAOYSA-N	25115	3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(pyrrolidin-1-yl)butyl]carbamoyl}amino)-1,2-thiazole-4-carboxamide::CHEMBL253969::CP 547632::CP547632, 24::US9446026, 1	Epidermal growth factor receptor	Homo sapiens		 5853.40							US Patent		10.7270/Q2BK1B77		aid1803412	US9446026	Bingaman, DP; Chaney, PG; Wax, MB	9/20/2016	9/5/2017	PanOptica, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25115&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	BFF	3L8S	9811611	56374257		CHEMBL253969				ZINC03834191	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
478989	COc1ccc(Nc2ncc3ncc(=O)n(-c4ccc(N)cc4)c3n2)cc1	InChI=1S/C19H16N6O2/c1-27-15-8-4-13(5-9-15)23-19-22-10-16-18(24-19)25(17(26)11-21-16)14-6-2-12(20)3-7-14/h2-11H,20H2,1H3,(H,22,23,24)	HJHJLSAFDLUSPN-UHFFFAOYSA-N	195081	US9670213, Compound 001 8-(4-aminophenyl)-2-(4-methoxyphenyl)-7(8H)-pteridin-one	Epidermal growth factor receptor	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195081	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195081&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72712977	375075164							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
478993	COc1ccc(Nc2ncc3ncc(=O)n(-c4ccc(NC(=O)C=C)cc4)c3n2)cc1	InChI=1S/C22H18N6O3/c1-3-19(29)25-14-4-8-16(9-5-14)28-20(30)13-23-18-12-24-22(27-21(18)28)26-15-6-10-17(31-2)11-7-15/h3-13H,1H2,2H3,(H,25,29)(H,24,26,27)	BPENWXBDNSHEHD-UHFFFAOYSA-N	195857	US9670213, Compound 002 N-(4-(2-(4-methoxyphenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl)acrylamide	Epidermal growth factor receptor	Homo sapiens		 446						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195857	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195857&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713172	375075352							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
478997	C=CC(=O)Nc1ccc(cc1)-n1c2nc(Nc3ccc(cc3)N3CCOCC3)ncc2ncc1=O	InChI=1S/C25H23N7O3/c1-2-22(33)28-17-5-9-20(10-6-17)32-23(34)16-26-21-15-27-25(30-24(21)32)29-18-3-7-19(8-4-18)31-11-13-35-14-12-31/h2-10,15-16H,1,11-14H2,(H,28,33)(H,27,29,30)	CHFSRPYBDAIBQR-UHFFFAOYSA-N	195858	US9670213, Compound 003 N-(4-(2-(4-morpholino-phenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl)acrylamide	Epidermal growth factor receptor	Homo sapiens		 8011						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195858	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195858&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713176	375075353							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479001	COc1ccc(Nc2ncc3nc(C)c(=O)n(-c4ccc(NC(=O)C=C)cc4)c3n2)cc1	InChI=1S/C23H20N6O3/c1-4-20(30)26-15-5-9-17(10-6-15)29-21-19(25-14(2)22(29)31)13-24-23(28-21)27-16-7-11-18(32-3)12-8-16/h4-13H,1H2,2-3H3,(H,26,30)(H,24,27,28)	WZUJQAJDFCNKQS-UHFFFAOYSA-N	195859	US9670213, Compound 004 N-(4-(2-(4-methoxyphenylamino)-6-methyl-7-oxo-8(7H)-pteridin-yl)phenyl)acrylamide	Epidermal growth factor receptor	Homo sapiens		 3181						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195859	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195859&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713386	375075354							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479005	COc1ccc(Nc2ncc3ncc(=O)n(-c4cccc(N)c4)c3n2)cc1	InChI=1S/C19H16N6O2/c1-27-15-7-5-13(6-8-15)23-19-22-10-16-18(24-19)25(17(26)11-21-16)14-4-2-3-12(20)9-14/h2-11H,20H2,1H3,(H,22,23,24)	QKANEQHLFOWQRR-UHFFFAOYSA-N	195860	US9670213, Compound 005 8-(3-aminophenyl)-2-(4-methoxyphenyl)-7(8H)-pteridin-one	Epidermal growth factor receptor	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195860&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72712978	375075355							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479009	COc1ccc(Nc2ncc3ncc(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C22H18N6O3/c1-3-19(29)25-15-5-4-6-16(11-15)28-20(30)13-23-18-12-24-22(27-21(18)28)26-14-7-9-17(31-2)10-8-14/h3-13H,1H2,2H3,(H,25,29)(H,24,26,27)	BLWDOLCMBQDSMT-UHFFFAOYSA-N	195861	US9670213, Compound 006 N-(3-(2-(4-methoxyphenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 11						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195861&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202734	375075356							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479013	CCC(=O)Nc1cccc(c1)-n1c2nc(Nc3ccc(OC)cc3)ncc2ncc1=O	InChI=1S/C22H20N6O3/c1-3-19(29)25-15-5-4-6-16(11-15)28-20(30)13-23-18-12-24-22(27-21(18)28)26-14-7-9-17(31-2)10-8-14/h4-13H,3H2,1-2H3,(H,25,29)(H,24,26,27)	WFRGDRJJKWAQDS-UHFFFAOYSA-N	195862	US9670213, Compound 007 N-(3-(2-(4-methoxyphenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) propionamide	Epidermal growth factor receptor	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195862&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203002	375075357							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479017	CCC(=O)Nc1ccc(cc1)-n1c2nc(Nc3ccc(OC)cc3)ncc2ncc1=O	InChI=1S/C22H20N6O3/c1-3-19(29)25-14-4-8-16(9-5-14)28-20(30)13-23-18-12-24-22(27-21(18)28)26-15-6-10-17(31-2)11-7-15/h4-13H,3H2,1-2H3,(H,25,29)(H,24,26,27)	PUAZSJAPNIJEFA-UHFFFAOYSA-N	195863	US9670213, Compound 008 N-(4-(2-(4-methoxyphenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) propionamide	Epidermal growth factor receptor	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195863&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713173	375075358							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479021	COc1ccc(Nc2ncc3ncc(=O)n(-c4ccc(NC(=O)\C=C\CN(C)C)cc4)c3n2)cc1	InChI=1S/C25H25N7O3/c1-31(2)14-4-5-22(33)28-17-6-10-19(11-7-17)32-23(34)16-26-21-15-27-25(30-24(21)32)29-18-8-12-20(35-3)13-9-18/h4-13,15-16H,14H2,1-3H3,(H,28,33)(H,27,29,30)/b5-4+	ZVPLRCNYKVNOMV-SNAWJCMRSA-N	195864	US9670213, Compound 009 4-(dimethylamino)-N-(4-(2-(4-methoxyphenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl)-2-buteneamide	Epidermal growth factor receptor	Homo sapiens		 61						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195864&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713174	375075359							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479025	COc1ccc(Nc2ncc3ncc(=O)n(-c4cccc(NC(=O)\C=C\CN(C)C)c4)c3n2)cc1	InChI=1S/C25H25N7O3/c1-31(2)13-5-8-22(33)28-18-6-4-7-19(14-18)32-23(34)16-26-21-15-27-25(30-24(21)32)29-17-9-11-20(35-3)12-10-17/h4-12,14-16H,13H2,1-3H3,(H,28,33)(H,27,29,30)/b8-5+	SJMNSZVROFACMM-VMPITWQZSA-N	195865	US9670213, Compound 010 4-(dimethylamino)-N-(3-(2-(4-methoxyphenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl)-2-buteneamide	Epidermal growth factor receptor	Homo sapiens		 8086						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195865&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203136	375075360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479028	COc1ccc(Nc2ncc3ncc(=O)n(-c4ccc(OC(=O)C=C)cc4)c3n2)cc1	InChI=1S/C22H17N5O4/c1-3-20(29)31-17-10-6-15(7-11-17)27-19(28)13-23-18-12-24-22(26-21(18)27)25-14-4-8-16(30-2)9-5-14/h3-13H,1H2,2H3,(H,24,25,26)	UFEYPVTVHUTYJF-UHFFFAOYSA-N	195866	US9670213, Compound 011 4-(2 (4-methoxyphenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl acrylate	Epidermal growth factor receptor	Homo sapiens		 67						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195866&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203001	375075361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479031	CN(C)C\C=C\C(=O)Nc1ccc(cc1)-n1c2nc(Nc3ccccc3)ncc2ncc1=O	InChI=1S/C24H23N7O2/c1-30(2)14-6-9-21(32)27-18-10-12-19(13-11-18)31-22(33)16-25-20-15-26-24(29-23(20)31)28-17-7-4-3-5-8-17/h3-13,15-16H,14H2,1-2H3,(H,27,32)(H,26,28,29)/b9-6+	KGPLGVFZWCSDMU-RMKNXTFCSA-N	195867	US9670213, Compound 012 4-(dimethylamino)-N-(4-(7-oxo-2-(phenylamino)-8(7H)-pteridin-yl)phenyl)-2-buteneamide	Epidermal growth factor receptor	Homo sapiens		 5980						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195867&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203135	375075362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479034	CN(C)C\C=C\C(=O)Nc1cccc(c1)-n1c2nc(Nc3ccccc3)ncc2ncc1=O	InChI=1S/C24H23N7O2/c1-30(2)13-7-12-21(32)27-18-10-6-11-19(14-18)31-22(33)16-25-20-15-26-24(29-23(20)31)28-17-8-4-3-5-9-17/h3-12,14-16H,13H2,1-2H3,(H,27,32)(H,26,28,29)/b12-7+	DYLDTESCOKKPMG-KPKJPENVSA-N	195868	US9670213, Compound 013 4-(dimethylamino)-N-(3-(7-oxo-2-(phenylamino)-8(7H)-pteridin-yl)phenyl)-2-buteneamide	Epidermal growth factor receptor	Homo sapiens		 87						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195868&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203134	375075363							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479037	C=CC(=O)Nc1ccc(cc1)-n1c2nc(Nc3ccccc3)ncc2ncc1=O	InChI=1S/C21H16N6O2/c1-2-18(28)24-15-8-10-16(11-9-15)27-19(29)13-22-17-12-23-21(26-20(17)27)25-14-6-4-3-5-7-14/h2-13H,1H2,(H,24,28)(H,23,25,26)	SKEYVRLMSNIOGI-UHFFFAOYSA-N	195869	US9670213, Compound 014 N-(4-(7-oxo-2-(phenylamino)-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 16						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195869&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203000	375075364							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479040	C=CC(=O)Nc1cccc(c1)-n1c2nc(Nc3ccccc3)ncc2ncc1=O	InChI=1S/C21H16N6O2/c1-2-18(28)24-15-9-6-10-16(11-15)27-19(29)13-22-17-12-23-21(26-20(17)27)25-14-7-4-3-5-8-14/h2-13H,1H2,(H,24,28)(H,23,25,26)	CMZKQVFPFYPHOD-UHFFFAOYSA-N	195870	US9670213, Compound 015 N-(3-(7-oxo-2-(phenylamino)-8(7H)-pteridin-yl)phenyl)acrylamide	Epidermal growth factor receptor	Homo sapiens		 15						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195870&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202999	375075365							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479043	Clc1ccc(Nc2ncc3ncc(=O)n(-c4ccc(NC(=O)C=C)cc4)c3n2)cc1	InChI=1S/C21H15ClN6O2/c1-2-18(29)25-14-7-9-16(10-8-14)28-19(30)12-23-17-11-24-21(27-20(17)28)26-15-5-3-13(22)4-6-15/h2-12H,1H2,(H,25,29)(H,24,26,27)	YQVNLEYHEXIBNV-UHFFFAOYSA-N	195871	US9670213, Compound 016 N-(4-(2-(4-chlorophenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 7580						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195871&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713175	375075366							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479046	Clc1ccc(Nc2ncc3ncc(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C21H15ClN6O2/c1-2-18(29)25-15-4-3-5-16(10-15)28-19(30)12-23-17-11-24-21(27-20(17)28)26-14-8-6-13(22)7-9-14/h2-12H,1H2,(H,25,29)(H,24,26,27)	NPYHVKHWRDSLAV-UHFFFAOYSA-N	195872	US9670213, Compound 017 N-(3-(2-(4-chlorophenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 67						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195872&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202870	375075367							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479049	C=CC(=O)Nc1cccc(c1)-n1c2nc(Nc3ccc(cc3)N3CCOCC3)ncc2ncc1=O	InChI=1S/C25H23N7O3/c1-2-22(33)28-18-4-3-5-20(14-18)32-23(34)16-26-21-15-27-25(30-24(21)32)29-17-6-8-19(9-7-17)31-10-12-35-13-11-31/h2-9,14-16H,1,10-13H2,(H,28,33)(H,27,29,30)	NXZQKEJXOSVRFZ-UHFFFAOYSA-N	195873	US9670213, Compound 018 N-(3-(2-(4-morpholinophenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 7.94						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195873&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203003	375075368							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479052	CN1CCN(CC1)c1ccc(Nc2ncc3ncc(=O)n(-c4ccc(NC(=O)C=C)cc4)c3n2)cc1	InChI=1S/C26H26N8O2/c1-3-23(35)29-18-6-10-21(11-7-18)34-24(36)17-27-22-16-28-26(31-25(22)34)30-19-4-8-20(9-5-19)33-14-12-32(2)13-15-33/h3-11,16-17H,1,12-15H2,2H3,(H,29,35)(H,28,30,31)	DRGNKFXIAXKCCX-UHFFFAOYSA-N	195874	US9670213, Compound 019 N-(4-(2-(4-(4-methyl-1-piperazinyl)-phenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 1260						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195874&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72203004	375075369							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479055	CN1CCN(CC1)c1ccc(Nc2ncc3ncc(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C26H26N8O2/c1-3-23(35)29-19-5-4-6-21(15-19)34-24(36)17-27-22-16-28-26(31-25(22)34)30-18-7-9-20(10-8-18)33-13-11-32(2)12-14-33/h3-10,15-17H,1,11-14H2,2H3,(H,29,35)(H,28,30,31)	JJQDZMPHVLCCFS-UHFFFAOYSA-N	195875	US9670213, Compound 020 N-(3-(2-(4-(4-methyl-1-piperazinyl)-phenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 1.47						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195875&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72187684	375075370							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479058	C=CC(=O)Nc1cccc(c1)-n1c2nc(Nc3ccc(cc3)N3CCCCC3)ncc2ncc1=O	InChI=1S/C26H25N7O2/c1-2-23(34)29-19-7-6-8-21(15-19)33-24(35)17-27-22-16-28-26(31-25(22)33)30-18-9-11-20(12-10-18)32-13-4-3-5-14-32/h2,6-12,15-17H,1,3-5,13-14H2,(H,29,34)(H,28,30,31)	VJFSMDWEMFOWDK-UHFFFAOYSA-N	195876	US9670213, Compound 021 N-(3-(7-oxo-2-(4-(1-piperidinyl)phenylamino)-8(7H)-pteridinyl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 20						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195876&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713177	375075371							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479061	C=CC(=O)Nc1cccc(c1)-n1c2nc(Nc3ccc(cc3)N3CCCC3)ncc2ncc1=O	InChI=1S/C25H23N7O2/c1-2-22(33)28-18-6-5-7-20(14-18)32-23(34)16-26-21-15-27-25(30-24(21)32)29-17-8-10-19(11-9-17)31-12-3-4-13-31/h2,5-11,14-16H,1,3-4,12-13H2,(H,28,33)(H,27,29,30)	HKNZEEWNPHTWIR-UHFFFAOYSA-N	195877	US9670213, Compound 022 N-(3-(7-oxo-2-(4-(1-pyrrolidinyl)phenylamino)-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 23						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195877&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202867	375075372							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479064	CCN(CC)c1ccc(Nc2ncc3ncc(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C25H25N7O2/c1-4-22(33)28-18-8-7-9-20(14-18)32-23(34)16-26-21-15-27-25(30-24(21)32)29-17-10-12-19(13-11-17)31(5-2)6-3/h4,7-16H,1,5-6H2,2-3H3,(H,28,33)(H,27,29,30)	BIUVCZQWTOSTRS-UHFFFAOYSA-N	195878	US9670213, Compound 023 N-(3-(2-(4-(diethylamino)phenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 23						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195878&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202868	375075373							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479067	CC(=O)Nc1ccc(Nc2ncc3ncc(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C23H19N7O3/c1-3-20(32)27-17-5-4-6-18(11-17)30-21(33)13-24-19-12-25-23(29-22(19)30)28-16-9-7-15(8-10-16)26-14(2)31/h3-13H,1H2,2H3,(H,26,31)(H,27,32)(H,25,28,29)	JIJDVLXBQGQRQM-UHFFFAOYSA-N	195879	US9670213, Compound 024 N-(3-(2-(4-(acetylamino)-phenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 16						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195879&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202735	375075374							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479070	NC(=O)c1ccc(Nc2ncc3ncc(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C22H17N7O3/c1-2-18(30)26-15-4-3-5-16(10-15)29-19(31)12-24-17-11-25-22(28-21(17)29)27-14-8-6-13(7-9-14)20(23)32/h2-12H,1H2,(H2,23,32)(H,26,30)(H,25,27,28)	JWNAINYXINYHML-UHFFFAOYSA-N	195880	US9670213, Compound 025 4-(8-(3-acrylamidephenyl)-7-oxo-7,8-dihydropteridinyl-2-amino)benzamide	Epidermal growth factor receptor	Homo sapiens		 13						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195880&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202865	375075375							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479073	COc1ccc(Nc2ncc3nc(C)c(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C23H20N6O3/c1-4-20(30)26-16-6-5-7-17(12-16)29-21-19(25-14(2)22(29)31)13-24-23(28-21)27-15-8-10-18(32-3)11-9-15/h4-13H,1H2,2-3H3,(H,26,30)(H,24,27,28)	FGPPXNCHKYRZCI-UHFFFAOYSA-N	195881	US9670213, Compound 026 N-(3-(2-(4-methoxyphenylamino)-6-methyl-7-oxo-8(7H)-pteridin-yl)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 7.24						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195881&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713387	375075376							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479076	COc1ccc(cc1)-n1c2nc(Nc3cccc(NC(=O)C=C)c3)ncc2ncc1=O	InChI=1S/C22H18N6O3/c1-3-19(29)25-14-5-4-6-15(11-14)26-22-24-12-18-21(27-22)28(20(30)13-23-18)16-7-9-17(31-2)10-8-16/h3-13H,1H2,2H3,(H,25,29)(H,24,26,27)	ZZYRBJVUKKZJCS-UHFFFAOYSA-N	195882	US9670213, Compound 027 N-(3-(8-(4-methoxyphenyl)-7-oxo-7,8-dihydro-pteridin-2-amino)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		 2000						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195882&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72712980	375075377							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479079	COc1ccc(cc1)-n1c2nc(Nc3cccc(N)c3)ncc2ncc1=O	InChI=1S/C19H16N6O2/c1-27-15-7-5-14(6-8-15)25-17(26)11-21-16-10-22-19(24-18(16)25)23-13-4-2-3-12(20)9-13/h2-11H,20H2,1H3,(H,22,23,24)	FZEFYHUOKWGELA-UHFFFAOYSA-N	195883	US9670213, Compound 028 2-(3-aminophenylamino)-8-(4-methoxyphenyl)-7(8H)-pteridin-one	Epidermal growth factor receptor	Homo sapiens		 10603						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195883&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72712979	375075378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479082	COc1ccc(cc1)-n1c2nc(Nc3ccc(NC(=O)C=C)cc3)ncc2ncc1=O	InChI=1S/C22H18N6O3/c1-3-19(29)25-14-4-6-15(7-5-14)26-22-24-12-18-21(27-22)28(20(30)13-23-18)16-8-10-17(31-2)11-9-16/h3-13H,1H2,2H3,(H,25,29)(H,24,26,27)	YRFYHYFKPSFNSZ-UHFFFAOYSA-N	195884	US9670213, Compound 029 N-(4-(8-(4-methoxyphenyl)-7-oxo-7,8-dihydro-pteridin-2-amino)phenyl) acrylamide	Epidermal growth factor receptor	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195884&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202733	375075379							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479085	COc1ccc(cc1)-n1c2nc(Nc3ccc(N)cc3)ncc2ncc1=O	InChI=1S/C19H16N6O2/c1-27-15-8-6-14(7-9-15)25-17(26)11-21-16-10-22-19(24-18(16)25)23-13-4-2-12(20)3-5-13/h2-11H,20H2,1H3,(H,22,23,24)	SUEFUBDCBOJENJ-UHFFFAOYSA-N	195885	US9670213, Compound 030 2-(4-aminophenylamino)-8-(4-methoxyphenyl)-7(8H)-pteridin-one	Epidermal growth factor receptor	Homo sapiens		 3415						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195885&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202866	375075380							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479088	COc1cc(ccc1Nc1ncc2ncc(=O)n(-c3ccc(NC(=O)C=C)cc3)c2n1)N1CCN(C)CC1	InChI=1S/C27H28N8O3/c1-4-24(36)30-18-5-7-19(8-6-18)35-25(37)17-28-22-16-29-27(32-26(22)35)31-21-10-9-20(15-23(21)38-3)34-13-11-33(2)12-14-34/h4-10,15-17H,1,11-14H2,2-3H3,(H,30,36)(H,29,31,32)	BMYBPXJXNNXUJF-UHFFFAOYSA-N	195886	US9670213, Compound 031 N-(4-(2-(2-methoxy)-4-(4-methoxy-1-piperazinyl)-phenylamino)-7-oxo-8(7H)-pteridinyl)phenyl)acrylamide	Epidermal growth factor receptor	Homo sapiens		 429						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195886&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72713385	375075381							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479091	COc1cc(ccc1Nc1ncc2ncc(=O)n(-c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(C)CC1	InChI=1S/C27H28N8O3/c1-4-24(36)30-18-6-5-7-20(14-18)35-25(37)17-28-22-16-29-27(32-26(22)35)31-21-9-8-19(15-23(21)38-3)34-12-10-33(2)11-13-34/h4-9,14-17H,1,10-13H2,2-3H3,(H,30,36)(H,29,31,32)	YJAJTLZIWHYGPF-UHFFFAOYSA-N	195887	US9670213, Compound 032 N-(3-(2-(2-methoxy-4-(4-methyl-1-piperazinyl)-phenylamino)-7-oxo-8(7H)-pteridin-yl)phenyl)acrylamide	Epidermal growth factor receptor	Homo sapiens		 3.67						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=195887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=195887&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			72202732	375075382							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
479094	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1	InChI=1S/C25H27ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,33)(H,27,29,30)	ITTRLTNMFYIYPA-UHFFFAOYSA-N	50383274	CHEMBL1229592::US10167264, WZ4002::US9670213, WZ4002	Epidermal growth factor receptor	Homo sapiens		 9.58						25.00 C	US Patent		10.7270/Q23R0R1P		aid1795051	US9670213	Li, H; Xu, Y; Zhao, Z; Liu, X; Zhou, W; Bai, F; Xue, M; Zhang, L; Zhang, Y	6/6/2017	7/7/2018	East China University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383274&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0UN	7ZYN,5X2K,3IKA	44607530	160862357	61400	CHEMBL1229592				ZINC52509385	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480336	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H32F3N5O4/c1-2-39-11-13-40(14-12-39)17-19-4-3-18(15-23(19)32(33,34)35)31(42)38-28-27-22-16-20(5-7-24(22)44-29(27)28)43-25-9-10-36-30-21(25)6-8-26(41)37-30/h3-5,7,9-10,15-16,27-29H,2,6,8,11-14,17H2,1H3,(H,38,42)(H,36,37,41)/t27-,28-,29-/m0/s1	LAGFSKLMDVYLMX-AWCRTANDSA-N	199967	BDBM200762::US9670231, 1.1	Epidermal growth factor receptor	Homo sapiens		 0.500							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199967	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199967&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807422	375976145							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480340	FC(F)(F)CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H29F6N5O4/c33-31(34,35)16-43-11-9-42(10-12-43)15-18-2-1-17(13-22(18)32(36,37)38)30(45)41-27-26-21-14-19(3-5-23(21)47-28(26)27)46-24-7-8-39-29-20(24)4-6-25(44)40-29/h1-3,5,7-8,13-14,26-28H,4,6,9-12,15-16H2,(H,41,45)(H,39,40,44)/t26-,27-,28-/m0/s1	HBLCYSRWPOVDEM-KCHLEUMXSA-N	199968	US9670231, 1.2	Epidermal growth factor receptor	Homo sapiens		 249							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199968&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807423	375976146							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480345	CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C31H30F3N5O4/c1-38-10-12-39(13-11-38)16-18-3-2-17(14-22(18)31(32,33)34)30(41)37-27-26-21-15-19(4-6-23(21)43-28(26)27)42-24-8-9-35-29-20(24)5-7-25(40)36-29/h2-4,6,8-9,14-15,26-28H,5,7,10-13,16H2,1H3,(H,37,41)(H,35,36,40)/t26-,27-,28-/m0/s1	NECNOKMWRWJOGB-KCHLEUMXSA-N	199995	US9670231, 1.3::US9670231, 1.34	Epidermal growth factor receptor	Homo sapiens		 0.700							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199995&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189432	375976147							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480350	CCN1CCN(Cc2ccc(cc2F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C31H32FN5O4/c1-2-36-11-13-37(14-12-36)17-19-4-3-18(15-23(19)32)31(39)35-28-27-22-16-20(5-7-24(22)41-29(27)28)40-25-9-10-33-30-21(25)6-8-26(38)34-30/h3-5,7,9-10,15-16,27-29H,2,6,8,11-14,17H2,1H3,(H,35,39)(H,33,34,38)/t27-,28-,29-/m0/s1	MAJNIEIORMXOPT-AWCRTANDSA-N	199996	US9670231, 1.4	Epidermal growth factor receptor	Homo sapiens		 1.40							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199996&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189431	375976148							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480355	CCN1CCN(Cc2cc(cc(c2)C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H32F3N5O4/c1-2-39-9-11-40(12-10-39)17-18-13-19(15-20(14-18)32(33,34)35)31(42)38-28-27-23-16-21(3-5-24(23)44-29(27)28)43-25-7-8-36-30-22(25)4-6-26(41)37-30/h3,5,7-8,13-16,27-29H,2,4,6,9-12,17H2,1H3,(H,38,42)(H,36,37,41)/t27-,28-,29-/m0/s1	SWOLBBOITSRBEP-AWCRTANDSA-N	200004	US9670231, 1.5	Epidermal growth factor receptor	Homo sapiens		 2.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200004&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807425	375976149							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480359	CCN1CCN(Cc2cc(F)cc(c2)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C31H32FN5O4/c1-2-36-9-11-37(12-10-36)17-18-13-19(15-20(32)14-18)31(39)35-28-27-23-16-21(3-5-24(23)41-29(27)28)40-25-7-8-33-30-22(25)4-6-26(38)34-30/h3,5,7-8,13-16,27-29H,2,4,6,9-12,17H2,1H3,(H,35,39)(H,33,34,38)/t27-,28-,29-/m0/s1	YBQICLDGWWEPMS-AWCRTANDSA-N	200008	US9670231, 1.6	Epidermal growth factor receptor	Homo sapiens		 2.90							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200008&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807482	375976150							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480364	FC(F)(F)c1cc(ccc1CN1CCOCC1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C30H27F3N4O5/c31-30(32,33)21-13-16(1-2-17(21)15-37-9-11-40-12-10-37)29(39)36-26-25-20-14-18(3-5-22(20)42-27(25)26)41-23-7-8-34-28-19(23)4-6-24(38)35-28/h1-3,5,7-8,13-14,25-27H,4,6,9-12,15H2,(H,36,39)(H,34,35,38)/t25-,26-,27-/m0/s1	CSRCFGWTAHVQEI-QKDODKLFSA-N	200212	US9670231, 1.7	Epidermal growth factor receptor	Homo sapiens		 9.80							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200212&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807410	375976151							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480369	FC(F)(F)c1cc(ccc1CN1CCCCC1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C31H29F3N4O4/c32-31(33,34)22-14-17(4-5-18(22)16-38-12-2-1-3-13-38)30(40)37-27-26-21-15-19(6-8-23(21)42-28(26)27)41-24-10-11-35-29-20(24)7-9-25(39)36-29/h4-6,8,10-11,14-15,26-28H,1-3,7,9,12-13,16H2,(H,37,40)(H,35,36,39)/t26-,27-,28-/m0/s1	MLISSYIWIFCVRT-KCHLEUMXSA-N	200214	US9670231, 1.8	Epidermal growth factor receptor	Homo sapiens		 70.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200214&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189453	375976152							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480373	CN(C)[C@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)C1	InChI=1S/C32H32F3N5O4/c1-39(2)19-10-12-40(16-19)15-18-4-3-17(13-23(18)32(33,34)35)31(42)38-28-27-22-14-20(5-7-24(22)44-29(27)28)43-25-9-11-36-30-21(25)6-8-26(41)37-30/h3-5,7,9,11,13-14,19,27-29H,6,8,10,12,15-16H2,1-2H3,(H,38,42)(H,36,37,41)/t19-,27-,28-,29-/m0/s1	HCVNIUYGKPAXGI-KKBDGGKNSA-N	200218	US9670231, 1.9	Epidermal growth factor receptor	Homo sapiens		 1.60							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200218&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807426	375976153							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480377	CN(C)[C@@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)C1	InChI=1S/C32H32F3N5O4/c1-39(2)19-10-12-40(16-19)15-18-4-3-17(13-23(18)32(33,34)35)31(42)38-28-27-22-14-20(5-7-24(22)44-29(27)28)43-25-9-11-36-30-21(25)6-8-26(41)37-30/h3-5,7,9,11,13-14,19,27-29H,6,8,10,12,15-16H2,1-2H3,(H,38,42)(H,36,37,41)/t19-,27+,28+,29+/m1/s1	HCVNIUYGKPAXGI-FDHJMSBKSA-N	200219	US9670231, 1.10	Epidermal growth factor receptor	Homo sapiens		 1.60							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200219&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807427	375976154							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480381	CN1CCN(Cc2ccc(cc2)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C30H31N5O4/c1-34-12-14-35(15-13-34)17-18-2-4-19(5-3-18)30(37)33-27-26-22-16-20(6-8-23(22)39-28(26)27)38-24-10-11-31-29-21(24)7-9-25(36)32-29/h2-6,8,10-11,16,26-28H,7,9,12-15,17H2,1H3,(H,33,37)(H,31,32,36)/t26-,27-,28-/m0/s1	SSQNYDRMXIRNEQ-KCHLEUMXSA-N	200335	US9670231, 1.11	Epidermal growth factor receptor	Homo sapiens		 1.28							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200335&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807493	375976155							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480386	FC(F)(F)c1cc(ccc1CN1CCN2CCC[C@@H]2C1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C33H32F3N5O4/c34-33(35,36)24-14-18(3-4-19(24)16-40-12-13-41-11-1-2-20(41)17-40)32(43)39-29-28-23-15-21(5-7-25(23)45-30(28)29)44-26-9-10-37-31-22(26)6-8-27(42)38-31/h3-5,7,9-10,14-15,20,28-30H,1-2,6,8,11-13,16-17H2,(H,39,43)(H,37,38,42)/t20-,28+,29+,30+/m1/s1	OHRLRZXRCWVJGT-KRUKBSHNSA-N	200336	US9670231, 1.12	Epidermal growth factor receptor	Homo sapiens		 0.670							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807485	375976156							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480390	C[C@H]1CN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)C[C@@H](C)O1	InChI=1S/C32H31F3N4O5/c1-16-13-39(14-17(2)42-16)15-19-4-3-18(11-23(19)32(33,34)35)31(41)38-28-27-22-12-20(5-7-24(22)44-29(27)28)43-25-9-10-36-30-21(25)6-8-26(40)37-30/h3-5,7,9-12,16-17,27-29H,6,8,13-15H2,1-2H3,(H,38,41)(H,36,37,40)/t16-,17+,27-,28-,29-/m0/s1	DSIYKUURMQSAAK-PLDGLXBGSA-N	200339	US9670231, 1.13	Epidermal growth factor receptor	Homo sapiens		 59.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200339&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807428	375976157							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480395	FC(F)(F)c1nnc2CN(Cc3ccc(cc3C(F)(F)F)C(=O)N[C@@H]3[C@H]4Oc5ccc(Oc6ccnc7NC(=O)CCc67)cc5[C@@H]34)CCn12	InChI=1S/C32H25F6N7O4/c33-31(34,35)20-11-15(1-2-16(20)13-44-9-10-45-23(14-44)42-43-30(45)32(36,37)38)29(47)41-26-25-19-12-17(3-5-21(19)49-27(25)26)48-22-7-8-39-28-18(22)4-6-24(46)40-28/h1-3,5,7-8,11-12,25-27H,4,6,9-10,13-14H2,(H,41,47)(H,39,40,46)/t25-,26-,27-/m0/s1	QXMGDURKHOLKQW-QKDODKLFSA-N	200474	US9670231, 1.14	Epidermal growth factor receptor	Homo sapiens		 5.10							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200474&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189434	375976158							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480400	O[C@H]1CCCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)C1	InChI=1S/C31H29F3N4O5/c32-31(33,34)22-12-16(3-4-17(22)14-38-11-1-2-18(39)15-38)30(41)37-27-26-21-13-19(5-7-23(21)43-28(26)27)42-24-9-10-35-29-20(24)6-8-25(40)36-29/h3-5,7,9-10,12-13,18,26-28,39H,1-2,6,8,11,14-15H2,(H,37,41)(H,35,36,40)/t18-,26-,27-,28-/m0/s1	QXIYODYFHMPKBX-ZGVXJWAQSA-N	200475	US9670231, 1.15	Epidermal growth factor receptor	Homo sapiens		 4.40							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200475&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189433	375976159							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480404	O[C@@H]1CCCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)C1	InChI=1S/C31H29F3N4O5/c32-31(33,34)22-12-16(3-4-17(22)14-38-11-1-2-18(39)15-38)30(41)37-27-26-21-13-19(5-7-23(21)43-28(26)27)42-24-9-10-35-29-20(24)6-8-25(40)36-29/h3-5,7,9-10,12-13,18,26-28,39H,1-2,6,8,11,14-15H2,(H,37,41)(H,35,36,40)/t18-,26+,27+,28+/m1/s1	QXIYODYFHMPKBX-CUPSYUBQSA-N	200476	US9670231, 1.16	Epidermal growth factor receptor	Homo sapiens		 4.20							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200476&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189416	375976160							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480408	OCCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H32F3N5O5/c33-32(34,35)23-15-18(1-2-19(23)17-40-11-9-39(10-12-40)13-14-41)31(43)38-28-27-22-16-20(3-5-24(22)45-29(27)28)44-25-7-8-36-30-21(25)4-6-26(42)37-30/h1-3,5,7-8,15-16,27-29,41H,4,6,9-14,17H2,(H,38,43)(H,36,37,42)/t27-,28-,29-/m0/s1	DXVUJULKKKBRPO-AWCRTANDSA-N	200477	US9670231, 1.17	Epidermal growth factor receptor	Homo sapiens		 1.40							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200477&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807453	375976161							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480412	CCN1CCN(Cc2ccc(cc2Cl)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C31H32ClN5O4/c1-2-36-11-13-37(14-12-36)17-19-4-3-18(15-23(19)32)31(39)35-28-27-22-16-20(5-7-24(22)41-29(27)28)40-25-9-10-33-30-21(25)6-8-26(38)34-30/h3-5,7,9-10,15-16,27-29H,2,6,8,11-14,17H2,1H3,(H,35,39)(H,33,34,38)/t27-,28-,29-/m0/s1	XRTHZTMBMXYKBQ-AWCRTANDSA-N	200478	US9670231, 1.18	Epidermal growth factor receptor	Homo sapiens		 0.700							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200478&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807532	375976162							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480416	CCN1CCN(Cc2ccc(cc2Br)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C31H32BrN5O4/c1-2-36-11-13-37(14-12-36)17-19-4-3-18(15-23(19)32)31(39)35-28-27-22-16-20(5-7-24(22)41-29(27)28)40-25-9-10-33-30-21(25)6-8-26(38)34-30/h3-5,7,9-10,15-16,27-29H,2,6,8,11-14,17H2,1H3,(H,35,39)(H,33,34,38)/t27-,28-,29-/m0/s1	VFRPNIRNEYDCSJ-AWCRTANDSA-N	200487	US9670231, 1.19	Epidermal growth factor receptor	Homo sapiens		 0.550							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200487&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807411	375976163							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480421	CN(C)C1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C33H34F3N5O4/c1-40(2)20-10-13-41(14-11-20)17-19-4-3-18(15-24(19)33(34,35)36)32(43)39-29-28-23-16-21(5-7-25(23)45-30(28)29)44-26-9-12-37-31-22(26)6-8-27(42)38-31/h3-5,7,9,12,15-16,20,28-30H,6,8,10-11,13-14,17H2,1-2H3,(H,39,43)(H,37,38,42)/t28-,29-,30-/m0/s1	OZFQDKCCDUEPFK-DTXPUJKBSA-N	200488	US9670231, 1.20	Epidermal growth factor receptor	Homo sapiens		 1.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200488&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807454	375976164							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480425	CN1CCN(Cc2ccc(cc2F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C30H30FN5O4/c1-35-10-12-36(13-11-35)16-18-3-2-17(14-22(18)31)30(38)34-27-26-21-15-19(4-6-23(21)40-28(26)27)39-24-8-9-32-29-20(24)5-7-25(37)33-29/h2-4,6,8-9,14-15,26-28H,5,7,10-13,16H2,1H3,(H,34,38)(H,32,33,37)/t26-,27-,28-/m0/s1	YDBGJXSBVYKNNA-KCHLEUMXSA-N	200489	US9670231, 1.21	Epidermal growth factor receptor	Homo sapiens		 1.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200489&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807515	375976165							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480429	CN1CCN(Cc2ccc(cc2Cl)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C30H30ClN5O4/c1-35-10-12-36(13-11-35)16-18-3-2-17(14-22(18)31)30(38)34-27-26-21-15-19(4-6-23(21)40-28(26)27)39-24-8-9-32-29-20(24)5-7-25(37)33-29/h2-4,6,8-9,14-15,26-28H,5,7,10-13,16H2,1H3,(H,34,38)(H,32,33,37)/t26-,27-,28-/m0/s1	SGGCXJXLKGOOEM-KCHLEUMXSA-N	200490	US9670231, 1.22	Epidermal growth factor receptor	Homo sapiens		 0.800							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200490&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189437	375976166							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480433	CN1CCN(Cc2ccc(cc2Br)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C30H30BrN5O4/c1-35-10-12-36(13-11-35)16-18-3-2-17(14-22(18)31)30(38)34-27-26-21-15-19(4-6-23(21)40-28(26)27)39-24-8-9-32-29-20(24)5-7-25(37)33-29/h2-4,6,8-9,14-15,26-28H,5,7,10-13,16H2,1H3,(H,34,38)(H,32,33,37)/t26-,27-,28-/m0/s1	XMHOUJITNCFQRT-KCHLEUMXSA-N	200491	US9670231, 1.23	Epidermal growth factor receptor	Homo sapiens		 1.10							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200491&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807430	375976167							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480438	CN(C)Cc1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C28H25F3N4O4/c1-35(2)13-15-4-3-14(11-19(15)28(29,30)31)27(37)34-24-23-18-12-16(5-7-20(18)39-25(23)24)38-21-9-10-32-26-17(21)6-8-22(36)33-26/h3-5,7,9-12,23-25H,6,8,13H2,1-2H3,(H,34,37)(H,32,33,36)/t23-,24-,25-/m0/s1	CQFUQADMAQYBOB-SDHOMARFSA-N	200492	US9670231, 1.24	Epidermal growth factor receptor	Homo sapiens		 2.70							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200492&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189438	375976168							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480443	CC(C)(N)c1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C28H25F3N4O4/c1-27(2,32)14-9-13(10-15(11-14)28(29,30)31)26(37)35-23-22-18-12-16(3-5-19(18)39-24(22)23)38-20-7-8-33-25-17(20)4-6-21(36)34-25/h3,5,7-12,22-24H,4,6,32H2,1-2H3,(H,35,37)(H,33,34,36)/t22-,23-,24-/m0/s1	CLJJOJZHQFORCB-HJOGWXRNSA-N	200497	US9670231, 1.25	Epidermal growth factor receptor	Homo sapiens		 0.480							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200497&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			86345833	375976169							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480448	NC1(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C28H23F3N4O4/c29-28(30,31)15-10-13(9-14(11-15)27(32)6-7-27)26(37)35-23-22-18-12-16(1-3-19(18)39-24(22)23)38-20-5-8-33-25-17(20)2-4-21(36)34-25/h1,3,5,8-12,22-24H,2,4,6-7,32H2,(H,35,37)(H,33,34,36)/t22-,23-,24-/m0/s1	LPOXCHABLAZUHB-HJOGWXRNSA-N	200498	US9670231, 1.26	Epidermal growth factor receptor	Homo sapiens		 1.70							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200498&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377604	375976170							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480453	FC(F)(F)c1cc(ccc1CN1CCNCC1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C30H28F3N5O4/c31-30(32,33)21-13-16(1-2-17(21)15-38-11-9-34-10-12-38)29(40)37-26-25-20-14-18(3-5-22(20)42-27(25)26)41-23-7-8-35-28-19(23)4-6-24(39)36-28/h1-3,5,7-8,13-14,25-27,34H,4,6,9-12,15H2,(H,37,40)(H,35,36,39)/t25-,26-,27-/m0/s1	VCCJAEXPICPGMM-QKDODKLFSA-N	200499	US9670231, 1.27	Epidermal growth factor receptor	Homo sapiens		 1.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200499&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807533	375976171							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480456	CCCCCCCCCCCC(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C29H37N3O4/c1-2-3-4-5-6-7-8-9-10-11-24(33)31-27-26-21-18-19(12-14-22(21)36-28(26)27)35-23-16-17-30-29-20(23)13-15-25(34)32-29/h12,14,16-18,26-28H,2-11,13,15H2,1H3,(H,31,33)(H,30,32,34)/t26-,27-,28-/m0/s1	SPTLACGKSKKWCI-KCHLEUMXSA-N	200500	US9670231, 1.28	Epidermal growth factor receptor	Homo sapiens		 809							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200500&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807432	375976172							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480461	C[C@H]1CN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CCN1	InChI=1S/C31H30F3N5O4/c1-16-14-39(11-10-35-16)15-18-3-2-17(12-22(18)31(32,33)34)30(41)38-27-26-21-13-19(4-6-23(21)43-28(26)27)42-24-8-9-36-29-20(24)5-7-25(40)37-29/h2-4,6,8-9,12-13,16,26-28,35H,5,7,10-11,14-15H2,1H3,(H,38,41)(H,36,37,40)/t16-,26-,27-,28-/m0/s1	CJRAVDZBPHZSKH-GTNRWADMSA-N	200501	US9670231, 1.29	Epidermal growth factor receptor	Homo sapiens		 0.610							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200501&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807499	375976173							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480464	C[C@@H]1CN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CCN1	InChI=1S/C31H30F3N5O4/c1-16-14-39(11-10-35-16)15-18-3-2-17(12-22(18)31(32,33)34)30(41)38-27-26-21-13-19(4-6-23(21)43-28(26)27)42-24-8-9-36-29-20(24)5-7-25(40)37-29/h2-4,6,8-9,12-13,16,26-28,35H,5,7,10-11,14-15H2,1H3,(H,38,41)(H,36,37,40)/t16-,26+,27+,28+/m1/s1	CJRAVDZBPHZSKH-MISNIXSYSA-N	200502	US9670231, 1.30	Epidermal growth factor receptor	Homo sapiens		 0.690							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200502&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807456	375976174							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480469	CN(C)[C@@H]1CCCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)C1	InChI=1S/C33H34F3N5O4/c1-40(2)20-4-3-13-41(17-20)16-19-6-5-18(14-24(19)33(34,35)36)32(43)39-29-28-23-15-21(7-9-25(23)45-30(28)29)44-26-11-12-37-31-22(26)8-10-27(42)38-31/h5-7,9,11-12,14-15,20,28-30H,3-4,8,10,13,16-17H2,1-2H3,(H,39,43)(H,37,38,42)/t20-,28+,29+,30+/m1/s1	DRWSMZPVRXENHA-KRUKBSHNSA-N	200503	US9670231, 1.31	Epidermal growth factor receptor	Homo sapiens		 0.990							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200503&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807431	375976175							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480474	CN(C)[C@@H]1CN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CCN1	InChI=1S/C32H33F3N6O4/c1-40(2)25-16-41(12-11-36-25)15-18-4-3-17(13-22(18)32(33,34)35)31(43)39-28-27-21-14-19(5-7-23(21)45-29(27)28)44-24-9-10-37-30-20(24)6-8-26(42)38-30/h3-5,7,9-10,13-14,25,27-29,36H,6,8,11-12,15-16H2,1-2H3,(H,39,43)(H,37,38,42)/t25-,27+,28+,29+/m1/s1	SABATKMFVISBCV-ZIZDPRJYSA-N	200504	US9670231, 1.32	Epidermal growth factor receptor	Homo sapiens		 1.50							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200504&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			134814164	375976176							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480479	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@H]2[C@@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@H]23)CC1	InChI=1S/C32H32F3N5O4/c1-2-39-11-13-40(14-12-39)17-19-4-3-18(15-23(19)32(33,34)35)31(42)38-28-27-22-16-20(5-7-24(22)44-29(27)28)43-25-9-10-36-30-21(25)6-8-26(41)37-30/h3-5,7,9-10,15-16,27-29H,2,6,8,11-14,17H2,1H3,(H,38,42)(H,36,37,41)/t27-,28-,29-/m1/s1	LAGFSKLMDVYLMX-MPFGFTFXSA-N	200505	US9670231, 1.33	Epidermal growth factor receptor	Homo sapiens		 774							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200505&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			86763661	375976177							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480483	CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C31H30F3N5O4/c1-38-10-12-39(13-11-38)16-18-3-2-17(14-22(18)31(32,33)34)30(41)37-27-26-21-15-19(4-6-23(21)43-28(26)27)42-24-8-9-35-29-20(24)5-7-25(40)36-29/h2-4,6,8-9,14-15,26-28H,5,7,10-13,16H2,1H3,(H,37,41)(H,35,36,40)/t26-,27-,28-/m0/s1	NECNOKMWRWJOGB-KCHLEUMXSA-N	199995	US9670231, 1.3::US9670231, 1.34	Epidermal growth factor receptor	Homo sapiens		 254							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199995&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189432	375976147							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480488	FC(F)(F)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-2-12(10-13)24(33)31-21-20-16-11-14(4-6-17(16)35-22(20)21)34-18-8-9-29-23-15(18)5-7-19(32)30-23/h1-4,6,8-11,20-22H,5,7H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1	NQSNNAVTPSOCHY-FKBYEOEOSA-N	200513	US9670231, 1.35	Epidermal growth factor receptor	Homo sapiens		 18.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200513&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807459	375976178							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480492	Fc1ccc(cc1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H18FN3O4/c25-13-3-1-12(2-4-13)24(30)28-21-20-16-11-14(5-7-17(16)32-22(20)21)31-18-9-10-26-23-15(18)6-8-19(29)27-23/h1-5,7,9-11,20-22H,6,8H2,(H,28,30)(H,26,27,29)/t20-,21-,22-/m0/s1	QHZJPRSLBCVVRJ-FKBYEOEOSA-N	200514	US9670231, 1.36	Epidermal growth factor receptor	Homo sapiens		 93.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200514&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189474	375976179							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480496	Cc1cccc(F)c1C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C25H20FN3O4/c1-12-3-2-4-16(26)20(12)25(31)29-22-21-15-11-13(5-7-17(15)33-23(21)22)32-18-9-10-27-24-14(18)6-8-19(30)28-24/h2-5,7,9-11,21-23H,6,8H2,1H3,(H,29,31)(H,27,28,30)/t21-,22-,23-/m0/s1	WVOVCPJQJLMEQC-VABKMULXSA-N	200515	US9670231, 1.37	Epidermal growth factor receptor	Homo sapiens		 1242							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200515&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189460	375976180							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480500	Fc1ccccc1C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H18FN3O4/c25-16-4-2-1-3-13(16)24(30)28-21-20-15-11-12(5-7-17(15)32-22(20)21)31-18-9-10-26-23-14(18)6-8-19(29)27-23/h1-5,7,9-11,20-22H,6,8H2,(H,28,30)(H,26,27,29)/t20-,21-,22-/m0/s1	SNGAWCAYCWMWIK-FKBYEOEOSA-N	200516	US9670231, 1.38	Epidermal growth factor receptor	Homo sapiens		 425							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200516&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189470	375976181							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480505	Fc1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H18FN3O4/c25-13-3-1-2-12(10-13)24(30)28-21-20-16-11-14(4-6-17(16)32-22(20)21)31-18-8-9-26-23-15(18)5-7-19(29)27-23/h1-4,6,8-11,20-22H,5,7H2,(H,28,30)(H,26,27,29)/t20-,21-,22-/m0/s1	BZHGOIYVJUGAQI-FKBYEOEOSA-N	200517	US9670231, 1.39	Epidermal growth factor receptor	Homo sapiens		 75.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200517&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189418	375976182							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480510	FC(F)(F)c1ccc(cc1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-12(2-4-13)24(33)31-21-20-16-11-14(5-7-17(16)35-22(20)21)34-18-9-10-29-23-15(18)6-8-19(32)30-23/h1-5,7,9-11,20-22H,6,8H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1	LSINTKBBQZHTHM-FKBYEOEOSA-N	200525	US9670231, 1.40	Epidermal growth factor receptor	Homo sapiens		 13.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200525&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807500	375976183							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480514	Fc1ccc(cc1F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H17F2N3O4/c25-15-4-1-11(9-16(15)26)24(31)29-21-20-14-10-12(2-5-17(14)33-22(20)21)32-18-7-8-27-23-13(18)3-6-19(30)28-23/h1-2,4-5,7-10,20-22H,3,6H2,(H,29,31)(H,27,28,30)/t20-,21-,22-/m0/s1	WUENUYHMSVASQE-FKBYEOEOSA-N	200526	US9670231, 1.41	Epidermal growth factor receptor	Homo sapiens		 59.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200526&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807486	375976184							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480518	Fc1cc(ccc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C25H17F4N3O4/c26-16-9-11(1-4-15(16)25(27,28)29)24(34)32-21-20-14-10-12(2-5-17(14)36-22(20)21)35-18-7-8-30-23-13(18)3-6-19(33)31-23/h1-2,4-5,7-10,20-22H,3,6H2,(H,32,34)(H,30,31,33)/t20-,21-,22-/m0/s1	XWIIFWOMOTZBMM-FKBYEOEOSA-N	200527	US9670231, 1.42	Epidermal growth factor receptor	Homo sapiens		 5.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200527&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807413	375976185							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480523	CC(C)(C#N)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C28H24N4O4/c1-28(2,14-29)16-5-3-4-15(12-16)27(34)32-24-23-19-13-17(6-8-20(19)36-25(23)24)35-21-10-11-30-26-18(21)7-9-22(33)31-26/h3-6,8,10-13,23-25H,7,9H2,1-2H3,(H,32,34)(H,30,31,33)/t23-,24-,25-/m0/s1	LGMCTZVEXBYIIM-SDHOMARFSA-N	200528	US9670231, 1.43	Epidermal growth factor receptor	Homo sapiens		 13.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200528&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189417	375976186							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480527	FC(F)(F)c1ccccc1C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C25H18F3N3O4/c26-25(27,28)16-4-2-1-3-13(16)24(33)31-21-20-15-11-12(5-7-17(15)35-22(20)21)34-18-9-10-29-23-14(18)6-8-19(32)30-23/h1-5,7,9-11,20-22H,6,8H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1	IQKGAJGOXQYVRX-FKBYEOEOSA-N	200529	US9670231, 1.44	Epidermal growth factor receptor	Homo sapiens		 243							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200529&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807503	375976187							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480531	FC(F)(F)c1ccnc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H17F3N4O4/c25-24(26,27)11-5-7-28-15(9-11)23(33)31-20-19-14-10-12(1-3-16(14)35-21(19)20)34-17-6-8-29-22-13(17)2-4-18(32)30-22/h1,3,5-10,19-21H,2,4H2,(H,31,33)(H,29,30,32)/t19-,20-,21-/m0/s1	VCYMOASGLMYUCI-ACRUOGEOSA-N	200536	US9670231, 1.45	Epidermal growth factor receptor	Homo sapiens		 8.50							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200536&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807462	375976188							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480535	O=C(N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12)c1cccc(c1)C1(CC1)C#N	InChI=1S/C28H22N4O4/c29-14-28(9-10-28)16-3-1-2-15(12-16)27(34)32-24-23-19-13-17(4-6-20(19)36-25(23)24)35-21-8-11-30-26-18(21)5-7-22(33)31-26/h1-4,6,8,11-13,23-25H,5,7,9-10H2,(H,32,34)(H,30,31,33)/t23-,24-,25-/m0/s1	OYALDUUQXBVIAL-SDHOMARFSA-N	200537	US9670231, 1.46	Epidermal growth factor receptor	Homo sapiens		 85.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200537&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807518	375976189							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480540	CN(C)[C@H]1CCCN(C1)c1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C32H32F3N5O4/c1-39(2)18-4-3-13-40(16-18)23-8-5-17(14-22(23)32(33,34)35)31(42)38-28-27-21-15-19(6-9-24(21)44-29(27)28)43-25-11-12-36-30-20(25)7-10-26(41)37-30/h5-6,8-9,11-12,14-15,18,27-29H,3-4,7,10,13,16H2,1-2H3,(H,38,42)(H,36,37,41)/t18-,27-,28-,29-/m0/s1	QJJUWHGSXUKRET-YMNBNBDKSA-N	200538	US9670231, 1.47	Epidermal growth factor receptor	Homo sapiens		 1.40							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377579	375976190							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480544	CN(C)[C@@H]1CCCN(C1)c1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C32H32F3N5O4/c1-39(2)18-4-3-13-40(16-18)23-8-5-17(14-22(23)32(33,34)35)31(42)38-28-27-21-15-19(6-9-24(21)44-29(27)28)43-25-11-12-36-30-20(25)7-10-26(41)37-30/h5-6,8-9,11-12,14-15,18,27-29H,3-4,7,10,13,16H2,1-2H3,(H,38,42)(H,36,37,41)/t18-,27+,28+,29+/m1/s1	QJJUWHGSXUKRET-MXQFTQDOSA-N	200539	US9670231, 1.48	Epidermal growth factor receptor	Homo sapiens		 1.70							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807519	375976191							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480549	CN1CCN(CC1)c1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C30H28F3N5O4/c1-37-10-12-38(13-11-37)21-5-2-16(14-20(21)30(31,32)33)29(40)36-26-25-19-15-17(3-6-22(19)42-27(25)26)41-23-8-9-34-28-18(23)4-7-24(39)35-28/h2-3,5-6,8-9,14-15,25-27H,4,7,10-13H2,1H3,(H,36,40)(H,34,35,39)/t25-,26-,27-/m0/s1	ONGVIYPMHRIZEX-QKDODKLFSA-N	200540	US9670231, 1.49	Epidermal growth factor receptor	Homo sapiens		 5.10							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807414	375976192							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480553	CCN1CCN(CC1)c1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C31H30F3N5O4/c1-2-38-11-13-39(14-12-38)22-6-3-17(15-21(22)31(32,33)34)30(41)37-27-26-20-16-18(4-7-23(20)43-28(26)27)42-24-9-10-35-29-19(24)5-8-25(40)36-29/h3-4,6-7,9-10,15-16,26-28H,2,5,8,11-14H2,1H3,(H,37,41)(H,35,36,40)/t26-,27-,28-/m0/s1	PITISSXVJPJKIL-KCHLEUMXSA-N	200547	US9670231, 1.50	Epidermal growth factor receptor	Homo sapiens		 6.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200547&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189456	375976193							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480558	CN1CCC(CC1)Oc1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C31H29F3N4O5/c1-38-12-9-17(10-13-38)41-24-5-2-16(14-21(24)31(32,33)34)30(40)37-27-26-20-15-18(3-6-22(20)43-28(26)27)42-23-8-11-35-29-19(23)4-7-25(39)36-29/h2-3,5-6,8,11,14-15,17,26-28H,4,7,9-10,12-13H2,1H3,(H,37,40)(H,35,36,39)/t26-,27-,28-/m0/s1	UGQSWPUGVJABLU-KCHLEUMXSA-N	200548	US9670231, 1.51	Epidermal growth factor receptor	Homo sapiens		 1.10							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200548&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807436	375976194							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480563	CN1CCN(CCOc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H32F3N5O5/c1-39-10-12-40(13-11-39)14-15-43-25-5-2-18(16-22(25)32(33,34)35)31(42)38-28-27-21-17-19(3-6-23(21)45-29(27)28)44-24-8-9-36-30-20(24)4-7-26(41)37-30/h2-3,5-6,8-9,16-17,27-29H,4,7,10-15H2,1H3,(H,38,42)(H,36,37,41)/t27-,28-,29-/m0/s1	IBUMJSAALUHRTO-AWCRTANDSA-N	200549	US9670231, 1.52	Epidermal growth factor receptor	Homo sapiens		 9.60							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200549&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189473	375976195							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480567	FC(F)(F)c1cccc(\C=C\C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)c1	InChI=1S/C27H20F3N3O4/c28-27(29,30)15-3-1-2-14(12-15)4-8-21(34)32-24-23-18-13-16(5-7-19(18)37-25(23)24)36-20-10-11-31-26-17(20)6-9-22(35)33-26/h1-5,7-8,10-13,23-25H,6,9H2,(H,32,34)(H,31,33,35)/b8-4+/t23-,24-,25-/m0/s1	NCUNGIOVSCCUQA-QRLZOZATSA-N	200550	US9670231, 1.53	Epidermal growth factor receptor	Homo sapiens		 678							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200550&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189472	375976196							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480571	O=C(N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12)c1ccc(o1)-c1ccccc1	InChI=1S/C28H21N3O5/c32-23-11-7-17-21(12-13-29-27(17)30-23)34-16-6-8-20-18(14-16)24-25(26(24)36-20)31-28(33)22-10-9-19(35-22)15-4-2-1-3-5-15/h1-6,8-10,12-14,24-26H,7,11H2,(H,31,33)(H,29,30,32)/t24-,25-,26-/m0/s1	WCYWGISTNUBZMN-GSDHBNRESA-N	200551	US9670231, 1.54	Epidermal growth factor receptor	Homo sapiens		 326							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200551&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807464	375976197							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480575	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)NC2C3Oc4c(cc(Oc5ccnc6NC(=O)CCc56)cc4C)C23)CC1	InChI=1S/C33H34F3N5O4/c1-3-40-10-12-41(13-11-40)17-20-5-4-19(15-24(20)33(34,35)36)32(43)39-28-27-23-16-21(14-18(2)29(23)45-30(27)28)44-25-8-9-37-31-22(25)6-7-26(42)38-31/h4-5,8-9,14-16,27-28,30H,3,6-7,10-13,17H2,1-2H3,(H,39,43)(H,37,38,42)	BYSBLMVAHXUQDT-UHFFFAOYSA-N	200584	US9670231, 1.55	Epidermal growth factor receptor	Homo sapiens		 2.20							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200584&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807404	375976198							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480579	CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)NC2C3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4C23)CC1	InChI=1S/C31H30F3N5O4/c1-38-10-12-39(13-11-38)16-18-3-2-17(14-22(18)31(32,33)34)30(41)37-27-26-21-15-19(4-6-23(21)43-28(26)27)42-24-8-9-35-29-20(24)5-7-25(40)36-29/h2-4,6,8-9,14-15,26-28H,5,7,10-13,16H2,1H3,(H,37,41)(H,35,36,40)	NECNOKMWRWJOGB-UHFFFAOYSA-N	200600	US9670231, 1.56	Epidermal growth factor receptor	Homo sapiens		 2.50							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200600&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			123674545	375976199							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480583	CCN1CCN(Cc2ccc(cc2C)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H35N5O4/c1-3-36-12-14-37(15-13-36)18-21-5-4-20(16-19(21)2)32(39)35-29-28-24-17-22(6-8-25(24)41-30(28)29)40-26-10-11-33-31-23(26)7-9-27(38)34-31/h4-6,8,10-11,16-17,28-30H,3,7,9,12-15,18H2,1-2H3,(H,35,39)(H,33,34,38)/t28-,29-,30-/m0/s1	SCGBVARXTMVSJL-DTXPUJKBSA-N	200627	US9670231, 1.57	Epidermal growth factor receptor	Homo sapiens		 1.50							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200627&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377585	375976200							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480587	CN1CCN(Cc2ccc(cc2C)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C31H33N5O4/c1-18-15-19(3-4-20(18)17-36-13-11-35(2)12-14-36)31(38)34-28-27-23-16-21(5-7-24(23)40-29(27)28)39-25-9-10-32-30-22(25)6-8-26(37)33-30/h3-5,7,9-10,15-16,27-29H,6,8,11-14,17H2,1-2H3,(H,34,38)(H,32,33,37)/t27-,28-,29-/m0/s1	XKQMUBZLWVCRQI-AWCRTANDSA-N	200630	US9670231, 1.58	Epidermal growth factor receptor	Homo sapiens		 1.20							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200630&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807446	375976201							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480591	Cc1cc(ccc1CO)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C26H23N3O5/c1-13-10-14(2-3-15(13)12-30)26(32)29-23-22-18-11-16(4-6-19(18)34-24(22)23)33-20-8-9-27-25-17(20)5-7-21(31)28-25/h2-4,6,8-11,22-24,30H,5,7,12H2,1H3,(H,29,32)(H,27,28,31)/t22-,23-,24-/m0/s1	NZFZJXGMCMWQJQ-HJOGWXRNSA-N	200757	US9670231, 1.59	Epidermal growth factor receptor	Homo sapiens		 19.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200757	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200757&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807445	375976202							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480595	FC(F)(F)c1cccc(CC(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)c1	InChI=1S/C26H20F3N3O4/c27-26(28,29)14-3-1-2-13(10-14)11-21(34)31-23-22-17-12-15(4-6-18(17)36-24(22)23)35-19-8-9-30-25-16(19)5-7-20(33)32-25/h1-4,6,8-10,12,22-24H,5,7,11H2,(H,31,34)(H,30,32,33)/t22-,23-,24-/m0/s1	CQLBJFSFGLKNEO-HJOGWXRNSA-N	200758	US9670231, 1.60	Epidermal growth factor receptor	Homo sapiens		 3448							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200758	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200758&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189439	375976203							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480599	FC(F)(F)c1cc(ccn1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H17F3N4O4/c25-24(26,27)17-9-11(5-7-28-17)23(33)31-20-19-14-10-12(1-3-15(14)35-21(19)20)34-16-6-8-29-22-13(16)2-4-18(32)30-22/h1,3,5-10,19-21H,2,4H2,(H,31,33)(H,29,30,32)/t19-,20-,21-/m0/s1	SZEJLGPLCDEGEZ-ACRUOGEOSA-N	200759	US9670231, 1.61	Epidermal growth factor receptor	Homo sapiens		 132							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200759&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807466	375976204							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480603	FC(F)(F)c1cncc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H17F3N4O4/c25-24(26,27)12-7-11(9-28-10-12)23(33)31-20-19-15-8-13(1-3-16(15)35-21(19)20)34-17-5-6-29-22-14(17)2-4-18(32)30-22/h1,3,5-10,19-21H,2,4H2,(H,31,33)(H,29,30,32)/t19-,20-,21-/m0/s1	REGQODFLIASNHU-ACRUOGEOSA-N	200760	US9670231, 1.62	Epidermal growth factor receptor	Homo sapiens		 42.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200760	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200760&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807419	375976205							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480607	FC(F)(F)c1cccc(n1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H17F3N4O4/c25-24(26,27)17-3-1-2-14(29-17)23(33)31-20-19-13-10-11(4-6-15(13)35-21(19)20)34-16-8-9-28-22-12(16)5-7-18(32)30-22/h1-4,6,8-10,19-21H,5,7H2,(H,31,33)(H,28,30,32)/t19-,20-,21-/m0/s1	OCQRIULERXCYIU-ACRUOGEOSA-N	200761	US9670231, 1.63	Epidermal growth factor receptor	Homo sapiens		 1140							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200761&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807465	375976206							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480611	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H32F3N5O4/c1-2-39-11-13-40(14-12-39)17-19-4-3-18(15-23(19)32(33,34)35)31(42)38-28-27-22-16-20(5-7-24(22)44-29(27)28)43-25-9-10-36-30-21(25)6-8-26(41)37-30/h3-5,7,9-10,15-16,27-29H,2,6,8,11-14,17H2,1H3,(H,38,42)(H,36,37,41)/t27-,28-,29-/m0/s1	LAGFSKLMDVYLMX-AWCRTANDSA-N	199967	BDBM200762::US9670231, 1.1	Epidermal growth factor receptor	Homo sapiens		 1.10							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199967	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199967&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807422	375976145							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480615	CC1CN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC(C)N1C(=O)OC(C)(C)C	InChI=1S/C37H40F3N5O6/c1-19-16-44(17-20(2)45(19)35(48)51-36(3,4)5)18-22-7-6-21(14-26(22)37(38,39)40)34(47)43-31-30-25-15-23(8-10-27(25)50-32(30)31)49-28-12-13-41-33-24(28)9-11-29(46)42-33/h6-8,10,12-15,19-20,30-32H,9,11,16-18H2,1-5H3,(H,43,47)(H,41,42,46)/t19?,20?,30-,31-,32-/m0/s1	TWMBIUXHLWHJHL-BOHBYMACSA-N	200763	US9670231, 1.65	Epidermal growth factor receptor	Homo sapiens		 1.90							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200763	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200763&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807504	375976208							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480619	CN(C)Cc1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C28H25F3N4O4/c1-35(2)13-14-9-15(11-16(10-14)28(29,30)31)27(37)34-24-23-19-12-17(3-5-20(19)39-25(23)24)38-21-7-8-32-26-18(21)4-6-22(36)33-26/h3,5,7-12,23-25H,4,6,13H2,1-2H3,(H,34,37)(H,32,33,36)/t23-,24-,25-/m0/s1	JAGSZFHNCZFFSR-SDHOMARFSA-N	200779	US9670231, 1.66	Epidermal growth factor receptor	Homo sapiens		 9.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807506	375976209							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480623	CCCCCC(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C23H25N3O4/c1-2-3-4-5-18(27)25-21-20-15-12-13(6-8-16(15)30-22(20)21)29-17-10-11-24-23-14(17)7-9-19(28)26-23/h6,8,10-12,20-22H,2-5,7,9H2,1H3,(H,25,27)(H,24,26,28)/t20-,21-,22-/m0/s1	RMBAGGGRKNUXIE-FKBYEOEOSA-N	200780	US9670231, 1.67	Epidermal growth factor receptor	Homo sapiens		 385							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200780&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807523	375976210							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480627	CCCCCCC(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C24H27N3O4/c1-2-3-4-5-6-19(28)26-22-21-16-13-14(7-9-17(16)31-23(21)22)30-18-11-12-25-24-15(18)8-10-20(29)27-24/h7,9,11-13,21-23H,2-6,8,10H2,1H3,(H,26,28)(H,25,27,29)/t21-,22-,23-/m0/s1	HQSBUBYPWIUFIL-VABKMULXSA-N	200781	US9670231, 1.68	Epidermal growth factor receptor	Homo sapiens		 98.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200781	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200781&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807537	375976211							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480631	CCCCCCCC(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C25H29N3O4/c1-2-3-4-5-6-7-20(29)27-23-22-17-14-15(8-10-18(17)32-24(22)23)31-19-12-13-26-25-16(19)9-11-21(30)28-25/h8,10,12-14,22-24H,2-7,9,11H2,1H3,(H,27,29)(H,26,28,30)/t22-,23-,24-/m0/s1	IWIONOUUGJGBPE-HJOGWXRNSA-N	200782	US9670231, 1.69	Epidermal growth factor receptor	Homo sapiens		 118							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200782	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200782&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807443	375976212					C16236		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480635	CCCCCCCCCC(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C27H33N3O4/c1-2-3-4-5-6-7-8-9-22(31)29-25-24-19-16-17(10-12-20(19)34-26(24)25)33-21-14-15-28-27-18(21)11-13-23(32)30-27/h10,12,14-16,24-26H,2-9,11,13H2,1H3,(H,29,31)(H,28,30,32)/t24-,25-,26-/m0/s1	SULSSSWEHDPZBW-GSDHBNRESA-N	200787	US9670231, 1.70	Epidermal growth factor receptor	Homo sapiens		 628							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200787	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200787&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807420	375976213							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480639	CN(C)C1CCN(CC1)c1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C32H32F3N5O4/c1-39(2)18-10-13-40(14-11-18)23-6-3-17(15-22(23)32(33,34)35)31(42)38-28-27-21-16-19(4-7-24(21)44-29(27)28)43-25-9-12-36-30-20(25)5-8-26(41)37-30/h3-4,6-7,9,12,15-16,18,27-29H,5,8,10-11,13-14H2,1-2H3,(H,38,42)(H,36,37,41)/t27-,28-,29-/m0/s1	XLPVELDHLJITBK-AWCRTANDSA-N	200788	US9670231, 1.71	Epidermal growth factor receptor	Homo sapiens		 2.70							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200788	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200788&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807509	375976214							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480643	COc1cc(ccc1CN1CCN(C)CC1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C31H33N5O5/c1-35-11-13-36(14-12-35)17-19-4-3-18(15-25(19)39-2)31(38)34-28-27-22-16-20(5-7-23(22)41-29(27)28)40-24-9-10-32-30-21(24)6-8-26(37)33-30/h3-5,7,9-10,15-16,27-29H,6,8,11-14,17H2,1-2H3,(H,34,38)(H,32,33,37)/t27-,28-,29-/m0/s1	DVYJHGWNABVCHI-AWCRTANDSA-N	200791	US9670231, 1.72	Epidermal growth factor receptor	Homo sapiens		 3.00							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200791	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200791&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807505	375976215							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480647	CCN1CCN(Cc2ccc(cc2OC)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H35N5O5/c1-3-36-12-14-37(15-13-36)18-20-5-4-19(16-26(20)40-2)32(39)35-29-28-23-17-21(6-8-24(23)42-30(28)29)41-25-10-11-33-31-22(25)7-9-27(38)34-31/h4-6,8,10-11,16-17,28-30H,3,7,9,12-15,18H2,1-2H3,(H,35,39)(H,33,34,38)/t28-,29-,30-/m0/s1	GJOOJNANCIXZSG-DTXPUJKBSA-N	200792	US9670231, 1.73	Epidermal growth factor receptor	Homo sapiens		 1.80							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200792	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200792&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807522	375976216							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480651	CCN1CCC(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C33H33F3N4O4/c1-2-40-13-10-18(11-14-40)15-19-3-4-20(16-24(19)33(34,35)36)32(42)39-29-28-23-17-21(5-7-25(23)44-30(28)29)43-26-9-12-37-31-22(26)6-8-27(41)38-31/h3-5,7,9,12,16-18,28-30H,2,6,8,10-11,13-15H2,1H3,(H,39,42)(H,37,38,41)/t28-,29-,30-/m0/s1	ASEMLWDIYZJALH-DTXPUJKBSA-N	200793	US9670231, 1.74	Epidermal growth factor receptor	Homo sapiens		 0.740							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200793	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200793&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377577	375976217							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480655	CCN1CCC(CC1)=Cc1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C33H31F3N4O4/c1-2-40-13-10-18(11-14-40)15-19-3-4-20(16-24(19)33(34,35)36)32(42)39-29-28-23-17-21(5-7-25(23)44-30(28)29)43-26-9-12-37-31-22(26)6-8-27(41)38-31/h3-5,7,9,12,15-17,28-30H,2,6,8,10-11,13-14H2,1H3,(H,39,42)(H,37,38,41)/t28-,29-,30-/m0/s1	OMTLURFNGXKURR-DTXPUJKBSA-N	200795	US9670231, 1.75	Epidermal growth factor receptor	Homo sapiens		 1.30							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200795&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807530	375976218							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480659	OCc1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C26H20F3N3O5/c27-26(28,29)17-9-12(1-2-13(17)11-33)25(35)32-22-21-16-10-14(3-5-18(16)37-23(21)22)36-19-7-8-30-24-15(19)4-6-20(34)31-24/h1-3,5,7-10,21-23,33H,4,6,11H2,(H,32,35)(H,30,31,34)/t21-,22-,23-/m0/s1	FRTFSQGVYAPBKY-VABKMULXSA-N	200796	US9670231, 1.76	Epidermal growth factor receptor	Homo sapiens		 4.20							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200796&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807472	375976219							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480663	CN1C(C)(C)CC(CC1(C)C)Oc1ccc(cc1C(F)(F)F)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12	InChI=1S/C35H37F3N4O5/c1-33(2)16-20(17-34(3,4)42(33)5)46-26-9-6-18(14-23(26)35(36,37)38)32(44)41-29-28-22-15-19(7-10-24(22)47-30(28)29)45-25-12-13-39-31-21(25)8-11-27(43)40-31/h6-7,9-10,12-15,20,28-30H,8,11,16-17H2,1-5H3,(H,41,44)(H,39,40,43)/t28-,29-,30-/m0/s1	XOWXEYBPOGNLJY-DTXPUJKBSA-N	200797	US9670231, 1.77	Epidermal growth factor receptor	Homo sapiens		 19.0							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200797&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377595	375976220							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480667	CCN1CCN(Cc2ccc(cc2OC(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1	InChI=1S/C32H32F3N5O5/c1-2-39-11-13-40(14-12-39)17-19-4-3-18(15-25(19)45-32(33,34)35)31(42)38-28-27-22-16-20(5-7-23(22)44-29(27)28)43-24-9-10-36-30-21(24)6-8-26(41)37-30/h3-5,7,9-10,15-16,27-29H,2,6,8,11-14,17H2,1H3,(H,38,42)(H,36,37,41)/t27-,28-,29-/m0/s1	NBPZAZKNOBYORP-AWCRTANDSA-N	200799	US9670231, 1.78	Epidermal growth factor receptor	Homo sapiens		 1.20							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200799&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377578	375976221							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480672	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)OCc56)cc4[C@@H]23)CC1	InChI=1S/C31H30F3N5O5/c1-2-38-9-11-39(12-10-38)15-18-4-3-17(13-22(18)31(32,33)34)29(40)36-26-25-20-14-19(5-6-23(20)44-27(25)26)43-24-7-8-35-28-21(24)16-42-30(41)37-28/h3-8,13-14,25-27H,2,9-12,15-16H2,1H3,(H,36,40)(H,35,37,41)/t25-,26-,27-/m0/s1	SJYYQCWAHXFERH-QKDODKLFSA-N	200800	US9670231, 2.1	Epidermal growth factor receptor	Homo sapiens		 1.80							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200800&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377603	375976222							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480676	CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)OCc56)cc4[C@@H]23)CC1	InChI=1S/C30H28F3N5O5/c1-37-8-10-38(11-9-37)14-17-3-2-16(12-21(17)30(31,32)33)28(39)35-25-24-19-13-18(4-5-22(19)43-26(24)25)42-23-6-7-34-27-20(23)15-41-29(40)36-27/h2-7,12-13,24-26H,8-11,14-15H2,1H3,(H,35,39)(H,34,36,40)/t24-,25-,26-/m0/s1	YWIRFAISLJFQCK-GSDHBNRESA-N	200801	US9670231, 2.2	Epidermal growth factor receptor	Homo sapiens		 1.50							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200801&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189484	375976223							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480681	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc(c5)C(=O)NC)cc4[C@@H]23)CC1	InChI=1S/C31H32F3N5O4/c1-3-38-10-12-39(13-11-38)17-19-5-4-18(14-23(19)31(32,33)34)29(40)37-27-26-22-15-20(6-7-25(22)43-28(26)27)42-21-8-9-36-24(16-21)30(41)35-2/h4-9,14-16,26-28H,3,10-13,17H2,1-2H3,(H,35,41)(H,37,40)/t26-,27-,28-/m0/s1	UYFPHIJXUONCKX-KCHLEUMXSA-N	200805	US9670231, 2.3	Epidermal growth factor receptor	Homo sapiens		 7.10							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200805&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121377582	375976224							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480685	CNC(=O)c1cc(Oc2ccc3O[C@@H]4[C@@H](NC(=O)c5ccc(CN6CCN(C)CC6)c(c5)C(F)(F)F)[C@@H]4c3c2)ccn1	InChI=1S/C30H30F3N5O4/c1-34-29(40)23-15-20(7-8-35-23)41-19-5-6-24-21(14-19)25-26(27(25)42-24)36-28(39)17-3-4-18(22(13-17)30(31,32)33)16-38-11-9-37(2)10-12-38/h3-8,13-15,25-27H,9-12,16H2,1-2H3,(H,34,40)(H,36,39)/t25-,26-,27-/m0/s1	XPTBKXUITCLALC-QKDODKLFSA-N	200806	US9670231, 2.4	Epidermal growth factor receptor	Homo sapiens		 6.80							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200806&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189573	375976225							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480689	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc(N)c5)cc4[C@@H]23)CC1	InChI=1S/C29H30F3N5O3/c1-2-36-9-11-37(12-10-36)16-18-4-3-17(13-22(18)29(30,31)32)28(38)35-26-25-21-14-19(5-6-23(21)40-27(25)26)39-20-7-8-34-24(33)15-20/h3-8,13-15,25-27H,2,9-12,16H2,1H3,(H2,33,34)(H,35,38)/t25-,26-,27-/m0/s1	HIQDSWJKNBQWTG-QKDODKLFSA-N	200807	US9670231, 2.5	Epidermal growth factor receptor	Homo sapiens		 4.10							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200807&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807474	375976226							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480693	CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)NCc56)cc4[C@@H]23)CC1	InChI=1S/C31H31F3N6O4/c1-2-39-9-11-40(12-10-39)16-18-4-3-17(13-22(18)31(32,33)34)29(41)37-26-25-20-14-19(5-6-23(20)44-27(25)26)43-24-7-8-35-28-21(24)15-36-30(42)38-28/h3-8,13-14,25-27H,2,9-12,15-16H2,1H3,(H,37,41)(H2,35,36,38,42)/t25-,26-,27-/m0/s1	CKHBRJUFFWJVQL-QKDODKLFSA-N	200809	US9670231, 2.6	Epidermal growth factor receptor	Homo sapiens		 0.430							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200809&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117807447	375976227							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
480697	CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)NCc56)cc4[C@@H]23)CC1	InChI=1S/C30H29F3N6O4/c1-38-8-10-39(11-9-38)15-17-3-2-16(12-21(17)30(31,32)33)28(40)36-25-24-19-13-18(4-5-22(19)43-26(24)25)42-23-6-7-34-27-20(23)14-35-29(41)37-27/h2-7,12-13,24-26H,8-11,14-15H2,1H3,(H,36,40)(H2,34,35,37,41)/t24-,25-,26-/m0/s1	FBHYBOKWBSZCDR-GSDHBNRESA-N	200810	US9670231, 2.7	Epidermal growth factor receptor	Homo sapiens		 0.670							US Patent		10.7270/Q2F18WWF		aid1795071	US9670231	Zhou, C; Zhang, G	6/6/2017	8/7/2018	BeiGene, Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=200810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=200810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129189442	375976228							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486847	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C25H25ClFN5O4/c1-34-21-11-19-16(25(29-14-28-19)30-15-4-5-18(27)17(26)9-15)10-20(21)31-24(33)3-2-6-32-12-22-23(13-32)36-8-7-35-22/h2-5,9-11,14,22-23H,6-8,12-13H2,1H3,(H,31,33)(H,28,29,30)/b3-2+/t22-,23+	REGOTSLWVKSZRG-GYQWKJCYSA-N	228107	 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4aR,7aS)-tetrahydro-2H-[1,4]dioxin[2,3-c]pyrrol-6(3H)-yl)but-2-enamide::US9556191, example 1	Epidermal growth factor receptor	Homo sapiens		 3.20					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228107&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			86729419	375077050							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486850	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@@H]2OCCO[C@H]2C1	InChI=1S/C25H25ClFN5O4/c1-34-21-11-19-16(25(29-14-28-19)30-15-4-5-18(27)17(26)9-15)10-20(21)31-24(33)3-2-6-32-12-22-23(13-32)36-8-7-35-22/h2-5,9-11,14,22-23H,6-8,12-13H2,1H3,(H,31,33)(H,28,29,30)/b3-2+/t22-,23-/m0/s1	REGOTSLWVKSZRG-JFWCZTBVSA-N	228108	(e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4as,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 2	Epidermal growth factor receptor	Homo sapiens		 4.30					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228108&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90331814	375077051							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486853	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C26H27ClFN5O4/c1-2-35-22-12-20-17(26(30-15-29-20)31-16-5-6-19(28)18(27)10-16)11-21(22)32-25(34)4-3-7-33-13-23-24(14-33)37-9-8-36-23/h3-6,10-12,15,23-24H,2,7-9,13-14H2,1H3,(H,32,34)(H,29,30,31)/b4-3+/t23-,24+	FKSFPUSFMMAXPK-LPZJDVQTSA-N	228109	(e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-ethoxyquinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxin[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 3	Epidermal growth factor receptor	Homo sapiens		 6.40					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228109&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462217	375077052							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486856	Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC(=O)\C=C\CN4C[C@H]5OCCO[C@H]5C4)cc23)cc1Cl	InChI=1S/C28H29ClFN5O5/c29-20-10-17(3-4-21(20)30)33-28-19-11-23(24(12-22(19)31-16-32-28)40-18-5-7-37-15-18)34-27(36)2-1-6-35-13-25-26(14-35)39-9-8-38-25/h1-4,10-12,16,18,25-26H,5-9,13-15H2,(H,34,36)(H,31,32,33)/b2-1+/t18-,25-,26+/m0/s1	QMXMLFJONMTABH-RSOJFYCWSA-N	228110	(e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(((s)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 5	Epidermal growth factor receptor	Homo sapiens		 3.60					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228110&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462194	375077053							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486859	COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C27H29ClFN5O5/c1-36-7-8-37-23-13-21-18(27(31-16-30-21)32-17-4-5-20(29)19(28)11-17)12-22(23)33-26(35)3-2-6-34-14-24-25(15-34)39-10-9-38-24/h2-5,11-13,16,24-25H,6-10,14-15H2,1H3,(H,33,35)(H,30,31,32)/b3-2+/t24-,25+	XXQCAOCIBBLKTR-AYVVYZBDSA-N	228111	(e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 6	Epidermal growth factor receptor	Homo sapiens		 1.80					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228111&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462576	375077054							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486862	Fc1ccc(Nc2ncnc3cc(OCC(F)(F)F)c(NC(=O)\C=C\CN4C[C@H]5OCCO[C@H]5C4)cc23)cc1Cl	InChI=1S/C26H24ClF4N5O4/c27-17-8-15(3-4-18(17)28)34-25-16-9-20(21(40-13-26(29,30)31)10-19(16)32-14-33-25)35-24(37)2-1-5-36-11-22-23(12-36)39-7-6-38-22/h1-4,8-10,14,22-23H,5-7,11-13H2,(H,35,37)(H,32,33,34)/b2-1+/t22-,23+	IGZLGJNZOKGZRZ-NNGMMJRYSA-N	228112	(e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(2,2,2-trifluoroethoxy)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 7	Epidermal growth factor receptor	Homo sapiens		 15.4					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228112&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462239	375077055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486865	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C25H25ClFN5O4/c1-34-21-11-19-16(25(29-14-28-19)30-15-4-5-18(27)17(26)9-15)10-20(21)31-24(33)3-2-6-32-12-22-23(13-32)36-8-7-35-22/h2-5,9-11,14,22-23H,6-8,12-13H2,1H3,(H,31,33)(H,28,29,30)/b3-2+/t22-,23+	REGOTSLWVKSZRG-GYQWKJCYSA-N	228113	(e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(methoxy-d3)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro 2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 20	Epidermal growth factor receptor	Homo sapiens		 4.80					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228113&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462221	375077056							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486868	Fc1cccc(COc2ccc(Nc3ncnc4ccc(NC(=O)\C=C\CN5C[C@H]6OCCO[C@H]6C5)cc34)cc2Cl)c1	InChI=1S/C31H29ClFN5O4/c32-25-15-23(7-9-27(25)42-18-20-3-1-4-21(33)13-20)37-31-24-14-22(6-8-26(24)34-19-35-31)36-30(39)5-2-10-38-16-28-29(17-38)41-12-11-40-28/h1-9,13-15,19,28-29H,10-12,16-18H2,(H,36,39)(H,34,35,37)/b5-2+/t28-,29+	RWQRIUWKYIAJRI-AGYHTPPKSA-N	228114	(e)-n-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 21	Epidermal growth factor receptor	Homo sapiens		 15.0					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228114&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473599	375077057							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486871	Clc1cc(Nc2ncnc3ccc(NC(=O)\C=C\CN4C[C@H]5OCCO[C@H]5C4)cc23)ccc1OCc1ccccn1	InChI=1S/C30H29ClN6O4/c31-24-15-21(7-9-26(24)41-18-22-4-1-2-10-32-22)36-30-23-14-20(6-8-25(23)33-19-34-30)35-29(38)5-3-11-37-16-27-28(17-37)40-13-12-39-27/h1-10,14-15,19,27-28H,11-13,16-18H2,(H,35,38)(H,33,34,36)/b5-3+/t27-,28+	GSSHFNOWTLFACP-OMYDXBOMSA-N	228115	(e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 22	Epidermal growth factor receptor	Homo sapiens		 22.0					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228115&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473600	375077058							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486874	COc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C31H31ClN6O5/c1-40-27-15-24-22(14-25(27)37-30(39)6-4-10-38-16-28-29(17-38)42-12-11-41-28)31(35-19-34-24)36-20-7-8-26(23(32)13-20)43-18-21-5-2-3-9-33-21/h2-9,13-15,19,28-29H,10-12,16-18H2,1H3,(H,37,39)(H,34,35,36)/b6-4+/t28-,29+	HMFQGZQQOSIJND-LQQDMUIFSA-N	228116	(e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4 ar,7as)tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 23	Epidermal growth factor receptor	Homo sapiens		 60.4					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228116&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90331667	375077059							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486877	CCOc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C32H33ClN6O5/c1-2-41-28-16-25-23(15-26(28)38-31(40)7-5-11-39-17-29-30(18-39)43-13-12-42-29)32(36-20-35-25)37-21-8-9-27(24(33)14-21)44-19-22-6-3-4-10-34-22/h3-10,14-16,20,29-30H,2,11-13,17-19H2,1H3,(H,38,40)(H,35,36,37)/b7-5+/t29-,30+	WEKWLJJTCAFJDA-LWXNEAQISA-N	228117	(e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 24	Epidermal growth factor receptor	Homo sapiens		 18.4					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228117&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90331845	375077060							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486880	Clc1cc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC(=O)\C=C\CN4C[C@H]5OCCO[C@H]5C4)cc23)ccc1OCc1ccccn1	InChI=1S/C34H35ClN6O6/c35-26-14-22(6-7-29(26)46-19-23-4-1-2-9-36-23)39-34-25-15-28(30(16-27(25)37-21-38-34)47-24-8-11-43-20-24)40-33(42)5-3-10-41-17-31-32(18-41)45-13-12-44-31/h1-7,9,14-16,21,24,31-32H,8,10-13,17-20H2,(H,40,42)(H,37,38,39)/b5-3+/t24-,31-,32+/m0/s1	VAMWYDFGORHXIU-XRCSGBKJSA-N	228118	(e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-(((s)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 25	Epidermal growth factor receptor	Homo sapiens		 8.60					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228118&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473601	375077061							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486883	Fc1cccc(Cn2ncc3cc(Nc4ncnc5ccc(NC(=O)\C=C\CN6C[C@H]7OCCO[C@H]7C6)cc45)ccc23)c1	InChI=1S/C32H30FN7O3/c33-23-4-1-3-21(13-23)17-40-28-9-7-24(14-22(28)16-36-40)38-32-26-15-25(6-8-27(26)34-20-35-32)37-31(41)5-2-10-39-18-29-30(19-39)43-12-11-42-29/h1-9,13-16,20,29-30H,10-12,17-19H2,(H,37,41)(H,34,35,38)/b5-2+/t29-,30+	IREADPMWGRIVEJ-WAARREDXSA-N	228119	(e)-n-(4-((1-(3-fluorobenzyl)-1h-indazol-5-yl)amino)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxin[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 26	Epidermal growth factor receptor	Homo sapiens		 14.0					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228119&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90331627	375077062							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486886	COc1cc2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C33H32FN7O4/c1-43-29-15-26-25(14-27(29)39-32(42)6-3-9-40-18-30-31(19-40)45-11-10-44-30)33(36-20-35-26)38-24-7-8-28-22(13-24)16-37-41(28)17-21-4-2-5-23(34)12-21/h2-8,12-16,20,30-31H,9-11,17-19H2,1H3,(H,39,42)(H,35,36,38)/b6-3+/t30-,31+	XRKMXTSLBXGSQT-MYOSJQCNSA-N	228120	(e)-n-(4-((1-(3-fluorobenzyl)-1h-indazol-5-yl)amino)-7-methoxyquinazolin-6-yl)-4-((4ar,7as)-tetra hydro-2h-[1,4]dioxin[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 27	Epidermal growth factor receptor	Homo sapiens		 7.90					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228120&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462158	375077063							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486889	CCOc1cc2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C34H34FN7O4/c1-2-44-30-16-27-26(15-28(30)40-33(43)7-4-10-41-19-31-32(20-41)46-12-11-45-31)34(37-21-36-27)39-25-8-9-29-23(14-25)17-38-42(29)18-22-5-3-6-24(35)13-22/h3-9,13-17,21,31-32H,2,10-12,18-20H2,1H3,(H,40,43)(H,36,37,39)/b7-4+/t31-,32+	LLDLKTHXNUZVDV-YDBLJOJBSA-N	228121	(e)-n-(7-ethoxy-4-((1-(3-fluorobenzyl)-1h-indazol-5-yl)amino)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 28	Epidermal growth factor receptor	Homo sapiens		 40.1					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228121&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462082	375077064							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486892	COc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C32H31ClFN5O5/c1-41-28-15-25-23(14-26(28)38-31(40)6-3-9-39-16-29-30(17-39)43-11-10-42-29)32(36-19-35-25)37-22-7-8-27(24(33)13-22)44-18-20-4-2-5-21(34)12-20/h2-8,12-15,19,29-30H,9-11,16-18H2,1H3,(H,38,40)(H,35,36,37)/b6-3+/t29-,30+	YVFMRJUBTQDNSA-LPUKYHPRSA-N	228122	(e)-n-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 29	Epidermal growth factor receptor	Homo sapiens		 22.6					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228122&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473627	375077065							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486895	CCOc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C33H33ClFN5O5/c1-2-42-29-16-26-24(15-27(29)39-32(41)7-4-10-40-17-30-31(18-40)44-12-11-43-30)33(37-20-36-26)38-23-8-9-28(25(34)14-23)45-19-21-5-3-6-22(35)13-21/h3-9,13-16,20,30-31H,2,10-12,17-19H2,1H3,(H,39,41)(H,36,37,38)/b7-4+/t30-,31+	KVXCGOZCGKXYQZ-ZYULESDQSA-N	228123	(e)-n-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-7-ethoxyquinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 30	Epidermal growth factor receptor	Homo sapiens		 31.9					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228123&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473631	375077066							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486898	COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C25H24Cl2FN5O4/c1-35-19-10-17-14(25(30-13-29-17)32-16-5-4-15(26)23(27)24(16)28)9-18(19)31-22(34)3-2-6-33-11-20-21(12-33)37-8-7-36-20/h2-5,9-10,13,20-21H,6-8,11-12H2,1H3,(H,31,34)(H,29,30,32)/b3-2+/t20-,21+	IKXRBNYJGLGKNN-YOAPFAFISA-N	228124	(e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 31	Epidermal growth factor receptor	Homo sapiens		 2.10					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228124&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473632	375077067							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486901	CCOc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C26H26Cl2FN5O4/c1-2-36-20-11-18-15(26(31-14-30-18)33-17-6-5-16(27)24(28)25(17)29)10-19(20)32-23(35)4-3-7-34-12-21-22(13-34)38-9-8-37-21/h3-6,10-11,14,21-22H,2,7-9,12-13H2,1H3,(H,32,35)(H,30,31,33)/b4-3+/t21-,22+	YHCWZWFXNSGDTJ-UFICKVLRSA-N	228125	(e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-ethoxyquinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 32	Epidermal growth factor receptor	Homo sapiens		 1.20					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228125&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473629	375077068							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486904	COCCOc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C27H28Cl2FN5O5/c1-37-7-8-38-21-12-19-16(27(32-15-31-19)34-18-5-4-17(28)25(29)26(18)30)11-20(21)33-24(36)3-2-6-35-13-22-23(14-35)40-10-9-39-22/h2-5,11-12,15,22-23H,6-10,13-14H2,1H3,(H,33,36)(H,31,32,34)/b3-2+/t22-,23+	CRKDDCRCAGBCAI-GYQWKJCYSA-N	228126	(e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 33	Epidermal growth factor receptor	Homo sapiens		 1.50					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228126&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89462256	375077069							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486907	Fc1c(Cl)c(Cl)ccc1Nc1ncnc2cc(O[C@H]3CCOC3)c(NC(=O)\C=C\CN3C[C@H]4OCCO[C@H]4C3)cc12	InChI=1S/C28H28Cl2FN5O5/c29-18-3-4-19(27(31)26(18)30)35-28-17-10-21(22(11-20(17)32-15-33-28)41-16-5-7-38-14-16)34-25(37)2-1-6-36-12-23-24(13-36)40-9-8-39-23/h1-4,10-11,15-16,23-24H,5-9,12-14H2,(H,34,37)(H,32,33,35)/b2-1+/t16-,23-,24+/m0/s1	KAJAEDXGWXUDJX-UTHPQMAGSA-N	228127	(e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-(((s)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 34	Epidermal growth factor receptor	Homo sapiens		 3.30					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228127&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473633	375077070							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
486910	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3F)c2cc1NC(=O)\C=C\CN1C[C@H]2OCCO[C@H]2C1	InChI=1S/C25H24ClF2N5O4/c1-35-19-10-17-14(25(30-13-29-17)32-16-5-4-15(27)23(26)24(16)28)9-18(19)31-22(34)3-2-6-33-11-20-21(12-33)37-8-7-36-20/h2-5,9-10,13,20-21H,6-8,11-12H2,1H3,(H,31,34)(H,29,30,32)/b3-2+/t20-,21+	YYQSQLGNBWMYFW-YOAPFAFISA-N	228128	(e)-n-(4-((3-chloro-2,4-difluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4ar,7as)-tetrahydro-2h-[1,4]dioxino[2,3-c]pyrrol-6(3h)-yl)but-2-enamide::US9556191, example 35	Epidermal growth factor receptor	Homo sapiens		 0.900					7.5	25.00 C	US Patent		10.7270/Q2FX7CF0		aid1795123	US9556191	Zhang, Y; Liu, B; Liu, J; Zhang, J; Cheng, C	1/31/2017	10/3/2018	Sunshine Lake Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228128&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			89473447	375077071							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502242	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCC1CO	InChI=1S/C23H23ClFN5O3/c1-33-21-11-19-16(23(27-13-26-19)28-14-4-5-18(25)17(24)9-14)10-20(21)29-22(32)3-2-7-30-8-6-15(30)12-31/h2-5,9-11,13,15,31H,6-8,12H2,1H3,(H,29,32)(H,26,27,28)/b3-2+	MCVGYROQTOADFC-NSCUHMNNSA-N	264128	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl)-4-(2-(hydroxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 1	Epidermal growth factor receptor	Homo sapiens		 2.30							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264128&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056475	377003013							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502244	COC[C@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC	InChI=1S/C24H25ClFN5O3/c1-33-13-16-7-9-31(16)8-3-4-23(32)30-21-11-17-20(12-22(21)34-2)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m1/s1	KYLTYWRKNDUYIL-QDLOVBKTSA-N	264129	(R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 2	Epidermal growth factor receptor	Homo sapiens		 1.60							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264129&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056553	377003014							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502246	COC[C@@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC	InChI=1S/C24H25ClFN5O3/c1-33-13-16-7-9-31(16)8-3-4-23(32)30-21-11-17-20(12-22(21)34-2)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1	KYLTYWRKNDUYIL-CWDCEQMOSA-N	264159	(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 3	Epidermal growth factor receptor	Homo sapiens		 21.5							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264159	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264159&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056554	377003043							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502248	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CC[C@@H]1COC	InChI=1S/C25H27ClFN5O3/c1-3-35-23-13-21-18(25(29-15-28-21)30-16-6-7-20(27)19(26)11-16)12-22(23)31-24(33)5-4-9-32-10-8-17(32)14-34-2/h4-7,11-13,15,17H,3,8-10,14H2,1-2H3,(H,31,33)(H,28,29,30)/b5-4+/t17-/m1/s1	YFFQYUIFTHZMHX-LAQIPUCWSA-N	264160	(R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxyquinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 4	Epidermal growth factor receptor	Homo sapiens		 2.00							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264160&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056555	377003044							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502250	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CC[C@H]1COC	InChI=1S/C25H27ClFN5O3/c1-3-35-23-13-21-18(25(29-15-28-21)30-16-6-7-20(27)19(26)11-16)12-22(23)31-24(33)5-4-9-32-10-8-17(32)14-34-2/h4-7,11-13,15,17H,3,8-10,14H2,1-2H3,(H,31,33)(H,28,29,30)/b5-4+/t17-/m0/s1	YFFQYUIFTHZMHX-BDUNBXCCSA-N	264161	(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxyquinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 5	Epidermal growth factor receptor	Homo sapiens		 7.80							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264161&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056556	377003045							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502252	COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CC[C@@H]1COC	InChI=1S/C26H29ClFN5O4/c1-35-10-11-37-24-14-22-19(26(30-16-29-22)31-17-5-6-21(28)20(27)12-17)13-23(24)32-25(34)4-3-8-33-9-7-18(33)15-36-2/h3-6,12-14,16,18H,7-11,15H2,1-2H3,(H,32,34)(H,29,30,31)/b4-3+/t18-/m1/s1	PCOFCPRYWPQQMW-OAJJDEHYSA-N	264162	(R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-methoxyethoxy)quinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 6	Epidermal growth factor receptor	Homo sapiens		 1.40							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264162&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			86764908	377003046							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502254	COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CC[C@H]1COC	InChI=1S/C26H29ClFN5O4/c1-35-10-11-37-24-14-22-19(26(30-16-29-22)31-17-5-6-21(28)20(27)12-17)13-23(24)32-25(34)4-3-8-33-9-7-18(33)15-36-2/h3-6,12-14,16,18H,7-11,15H2,1-2H3,(H,32,34)(H,29,30,31)/b4-3+/t18-/m0/s1	PCOFCPRYWPQQMW-WHLIDYPQSA-N	264163	(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-methoxyethoxy)quinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 7	Epidermal growth factor receptor	Homo sapiens		 5.80							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264163&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056557	377003047							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502256	OCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CC1	InChI=1S/C26H27ClFN5O3/c27-20-10-17(5-6-21(20)28)31-26-19-11-23(32-25(35)2-1-8-33-9-7-18(33)13-34)24(36-14-16-3-4-16)12-22(19)29-15-30-26/h1-2,5-6,10-12,15-16,18,34H,3-4,7-9,13-14H2,(H,32,35)(H,29,30,31)/b2-1+	GUHJZZKAWYPNAQ-OWOJBTEDSA-N	264164	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclopropylmethoxy)quinazolin-6-yl)-4-(2-(hydroxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 8	Epidermal growth factor receptor	Homo sapiens		 9.50							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264164&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056476	377003048							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502258	COC[C@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CC1	InChI=1S/C27H29ClFN5O3/c1-36-15-19-8-10-34(19)9-2-3-26(35)33-24-12-20-23(13-25(24)37-14-17-4-5-17)30-16-31-27(20)32-18-6-7-22(29)21(28)11-18/h2-3,6-7,11-13,16-17,19H,4-5,8-10,14-15H2,1H3,(H,33,35)(H,30,31,32)/b3-2+/t19-/m1/s1	ICKLZZYEDMBELM-LSTKMXGYSA-N	264165	(R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclopropylmethoxy)quinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 9	Epidermal growth factor receptor	Homo sapiens		 6.60							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264165&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056630	377003049							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502260	COC[C@@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CC1	InChI=1S/C27H29ClFN5O3/c1-36-15-19-8-10-34(19)9-2-3-26(35)33-24-12-20-23(13-25(24)37-14-17-4-5-17)30-16-31-27(20)32-18-6-7-22(29)21(28)11-18/h2-3,6-7,11-13,16-17,19H,4-5,8-10,14-15H2,1H3,(H,33,35)(H,30,31,32)/b3-2+/t19-/m0/s1	ICKLZZYEDMBELM-PHXNAMCJSA-N	264166	(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclopropylmethoxy)quinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 10	Epidermal growth factor receptor	Homo sapiens		 21.7							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264166&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056631	377003050							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502262	OCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1	InChI=1S/C26H27ClFN5O4/c27-20-10-16(3-4-21(20)28)31-26-19-11-23(32-25(35)2-1-7-33-8-5-17(33)13-34)24(12-22(19)29-15-30-26)37-18-6-9-36-14-18/h1-4,10-12,15,17-18,34H,5-9,13-14H2,(H,32,35)(H,29,30,31)/b2-1+/t17?,18-/m0/s1	NYHCGCDSBXKURV-SBPBPJATSA-N	264167	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(2-(hydroxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 11	Epidermal growth factor receptor	Homo sapiens		 3.90							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264167&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056716	377003051							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502264	COCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1	InChI=1S/C27H29ClFN5O4/c1-36-14-18-6-9-34(18)8-2-3-26(35)33-24-12-20-23(13-25(24)38-19-7-10-37-15-19)30-16-31-27(20)32-17-4-5-22(29)21(28)11-17/h2-5,11-13,16,18-19H,6-10,14-15H2,1H3,(H,33,35)(H,30,31,32)/b3-2+/t18?,19-/m0/s1	OVKAWEPHUVGRCJ-SQMXEVSSSA-N	264168	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 12	Epidermal growth factor receptor	Homo sapiens		 2.90							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264168&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056632	377003052							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502266	OCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@H]1COCCO1	InChI=1S/C27H29ClFN5O5/c28-21-10-17(3-4-22(21)29)32-27-20-11-24(33-26(36)2-1-6-34-7-5-18(34)13-35)25(12-23(20)30-16-31-27)39-15-19-14-37-8-9-38-19/h1-4,10-12,16,18-19,35H,5-9,13-15H2,(H,33,36)(H,30,31,32)/b2-1+/t18?,19-/m1/s1	QJNMNCUMDUMIJV-CBCWIBMJSA-N	264169	(E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(2-(hydroxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 13	Epidermal growth factor receptor	Homo sapiens		 2.70							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264169&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056633	377003053							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502268	COC[C@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@H]1COCCO1	InChI=1S/C28H31ClFN5O5/c1-37-14-19-6-8-35(19)7-2-3-27(36)34-25-12-21-24(13-26(25)40-16-20-15-38-9-10-39-20)31-17-32-28(21)33-18-4-5-23(30)22(29)11-18/h2-5,11-13,17,19-20H,6-10,14-16H2,1H3,(H,34,36)(H,31,32,33)/b3-2+/t19-,20-/m1/s1	KZBKXMGIJLJPHP-HNPUZTMESA-N	264170	(E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-((R)-2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 14	Epidermal growth factor receptor	Homo sapiens		 2.90							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264170&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056634	377003054							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502270	COC[C@@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@H]1COCCO1	InChI=1S/C28H31ClFN5O5/c1-37-14-19-6-8-35(19)7-2-3-27(36)34-25-12-21-24(13-26(25)40-16-20-15-38-9-10-39-20)31-17-32-28(21)33-18-4-5-23(30)22(29)11-18/h2-5,11-13,17,19-20H,6-10,14-16H2,1H3,(H,34,36)(H,31,32,33)/b3-2+/t19-,20+/m0/s1	KZBKXMGIJLJPHP-VQPVDWPJSA-N	264171	(E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-((S)-2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 15	Epidermal growth factor receptor	Homo sapiens		 25.0							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264171&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056712	377003055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502272	OCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@@H]1COCCO1	InChI=1S/C27H29ClFN5O5/c28-21-10-17(3-4-22(21)29)32-27-20-11-24(33-26(36)2-1-6-34-7-5-18(34)13-35)25(12-23(20)30-16-31-27)39-15-19-14-37-8-9-38-19/h1-4,10-12,16,18-19,35H,5-9,13-15H2,(H,33,36)(H,30,31,32)/b2-1+/t18?,19-/m0/s1	QJNMNCUMDUMIJV-OMSMFVMISA-N	264172	(E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(2-(hydroxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 16	Epidermal growth factor receptor	Homo sapiens		 17.5							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264172&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056713	377003056							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502274	COCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@@H]1COCCO1	InChI=1S/C28H31ClFN5O5/c1-37-14-19-6-8-35(19)7-2-3-27(36)34-25-12-21-24(13-26(25)40-16-20-15-38-9-10-39-20)31-17-32-28(21)33-18-4-5-23(30)22(29)11-18/h2-5,11-13,17,19-20H,6-10,14-16H2,1H3,(H,34,36)(H,31,32,33)/b3-2+/t19?,20-/m0/s1	KZBKXMGIJLJPHP-USNGRLKASA-N	264173	(E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 17	Epidermal growth factor receptor	Homo sapiens		 4.80							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264173&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056714	377003057							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502276	OCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@H]1[C@@H]2COC[C@H]12	InChI=1S/C28H29ClFN5O4/c29-22-8-16(3-4-23(22)30)33-28-18-9-25(34-27(37)2-1-6-35-7-5-17(35)11-36)26(10-24(18)31-15-32-28)39-14-21-19-12-38-13-20(19)21/h1-4,8-10,15,17,19-21,36H,5-7,11-14H2,(H,34,37)(H,31,32,33)/b2-1+/t17?,19-,20+,21+	ZHSPHEJVKURUJP-ONGSAVLISA-N	264174	(E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-ylmethoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(2-(hydroxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 18	Epidermal growth factor receptor	Homo sapiens		 10.8							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264174&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056715	377003058							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502278	COC[C@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@H]1[C@@H]2COC[C@H]12	InChI=1S/C29H31ClFN5O4/c1-38-12-18-6-8-36(18)7-2-3-28(37)35-26-10-19-25(11-27(26)40-15-22-20-13-39-14-21(20)22)32-16-33-29(19)34-17-4-5-24(31)23(30)9-17/h2-5,9-11,16,18,20-22H,6-8,12-15H2,1H3,(H,35,37)(H,32,33,34)/b3-2+/t18-,20-,21+,22+/m1/s1	XAHNKMWYZJATAR-PWZRHHMCSA-N	264175	(E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-ylmethoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-((R)-2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 19	Epidermal growth factor receptor	Homo sapiens		 2.90							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264175&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056793	377003059							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
502280	COC[C@@H]1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@H]1[C@@H]2COC[C@H]12	InChI=1S/C29H31ClFN5O4/c1-38-12-18-6-8-36(18)7-2-3-28(37)35-26-10-19-25(11-27(26)40-15-22-20-13-39-14-21(20)22)32-16-33-29(19)34-17-4-5-24(31)23(30)9-17/h2-5,9-11,16,18,20-22H,6-8,12-15H2,1H3,(H,35,37)(H,32,33,34)/b3-2+/t18-,20-,21+,22+/m0/s1	XAHNKMWYZJATAR-OBPLTNGCSA-N	264176	(E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-ylmethoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-((S)-2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 20	Epidermal growth factor receptor	Homo sapiens		 22.2							US Patent		10.7270/Q20G3N5P		aid1795309	US9714235	Wang, W; Zhao, X; Li, T; Tian, Q; Chen, L; Zhou, Z; Li, Z; Wang, X; Rong, Y; Jiang, L; Liu, Y; Sun, J; Zeng, F	7/25/2017	11/15/2018	Shanghai Fochon Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264176&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87056794	377003060							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511909	C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1	InChI=1S/C22H21N3O4/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20/h1,3-5,12-15H,6-11H2,(H,23,24,25)	QQLKULDARVNMAL-UHFFFAOYSA-N	50391089	BPI-2009::CHEMBL2087361::Conmana::Icotinib::Lcotinib::US9783524, Icotinib	Epidermal growth factor receptor	Homo sapiens		 1.23							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391089	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391089&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			22024915	160870172		CHEMBL2087361				ZINC43207566	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511913	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	AVL-301::CHEMBL3545308::CNX-419::CO-1686::Rociletinib::Tube721::US10167264, Compound CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4::US8975249, I-4::US9783524, CO-1686	Epidermal growth factor receptor	Homo sapiens		<0.51							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDL,5XDK	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511918	COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(N)=O)n1)N1CCC(CC1)N(C)C	InChI=1S/C26H30ClN7O3/c1-33(2)16-10-12-34(13-11-16)17-8-9-21(22(14-17)37-3)31-26-29-15-19(27)25(32-26)30-20-7-5-4-6-18(20)23(35)24(28)36/h4-9,14-16H,10-13H2,1-3H3,(H2,28,36)(H2,29,30,31,32)	AMSONZZHZCNUHV-UHFFFAOYSA-N	270538	US10059688, Example 4::US9783524, Example 4	Epidermal growth factor receptor	Homo sapiens		 45							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055587	378152421							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511923	COc1cc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)ccc1N1CCN(C)CC1	InChI=1S/C26H30ClN7O3/c1-32(2)25(36)23(35)18-7-5-6-8-20(18)30-24-19(27)16-28-26(31-24)29-17-9-10-21(22(15-17)37-4)34-13-11-33(3)12-14-34/h5-10,15-16H,11-14H2,1-4H3,(H2,28,29,30,31)	DIQHRPNVYBPCQW-UHFFFAOYSA-N	270539	2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-1-yl) phenylamino)pyrimidin-4- ylamino)phenyl)-N,N- dimethyl-2-oxoacetamide::US10059688, Example 61::US9783524, Example 61	Epidermal growth factor receptor	Homo sapiens		 756							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055101	378152422							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511928	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(=O)N(C)C)n1	InChI=1S/C24H23ClN6O4/c1-5-20(32)27-14-10-11-19(35-4)18(12-14)29-24-26-13-16(25)22(30-24)28-17-9-7-6-8-15(17)21(33)23(34)31(2)3/h5-13H,1H2,2-4H3,(H,27,32)(H2,26,28,29,30)	OKCOQQXHDZUFTL-UHFFFAOYSA-N	270540	N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacetyl) phenylamino)pyrimidin-2- ylamino)-4-methoxyphenyl) acrylamide::US10059688, Example 67::US9783524, Example 67	Epidermal growth factor receptor	Homo sapiens		 273							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055183	378152423							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511933	CN(C)C(=O)C(=O)c1ccccc1Nc1cc(Cl)ccc1Cl	InChI=1S/C16H14Cl2N2O2/c1-20(2)16(22)15(21)11-5-3-4-6-13(11)19-14-9-10(17)7-8-12(14)18/h3-9,19H,1-2H3	UEAQRTGQDQYAKL-UHFFFAOYSA-N	270541	US10059688, Example 74	Epidermal growth factor receptor	Homo sapiens		 513							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270541&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213671	378152424							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511938	CN(C)C(=O)C(=O)c1ccccc1Nc1nc(Nc2ccc3OCCN(C(=O)C=C)c3c2)ncc1Cl	InChI=1S/C25H23ClN6O4/c1-4-21(33)32-11-12-36-20-10-9-15(13-19(20)32)28-25-27-14-17(26)23(30-25)29-18-8-6-5-7-16(18)22(34)24(35)31(2)3/h4-10,13-14H,1,11-12H2,2-3H3,(H2,27,28,29,30)	KXPICMSXZCNILY-UHFFFAOYSA-N	270542	2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] oxazin-6-ylamino)-5- chloropyrimidin-4- ylamino)phenyl)-N,N- dimethyl-2-oxoacetamide::US10059688, Example 87::US9783524, Example 87	Epidermal growth factor receptor	Homo sapiens		 354							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055512	378152425							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511943	CN(C)CCOc1ccc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)cc1NC(=O)C=C	InChI=1S/C27H30ClN7O4/c1-6-23(36)31-21-15-17(11-12-22(21)39-14-13-34(2)3)30-27-29-16-19(28)25(33-27)32-20-10-8-7-9-18(20)24(37)26(38)35(4)5/h6-12,15-16H,1,13-14H2,2-5H3,(H,31,36)(H2,29,30,32,33)	WSDSYYCVRCLNSN-UHFFFAOYSA-N	270543	US10059688, Example 115::US9783524, Example 115	Epidermal growth factor receptor	Homo sapiens		 397							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270543&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117811098	378152426							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511948	COc1cc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)ccc1N1CCC(CC1)N(C)C	InChI=1S/C28H34ClN7O3/c1-34(2)19-12-14-36(15-13-19)23-11-10-18(16-24(23)39-5)31-28-30-17-21(29)26(33-28)32-22-9-7-6-8-20(22)25(37)27(38)35(3)4/h6-11,16-17,19H,12-15H2,1-5H3,(H2,30,31,32,33)	XYNBROWABUHURG-UHFFFAOYSA-N	270544	2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- 1-yl)-3-methoxyphenylamino) pyrimidin-4-ylamino)phenyl)- N,N-dimethyl-2-oxoacetamide::US10059688, Example 118::US9783524, Example 118	Epidermal growth factor receptor	Homo sapiens		 78							US Patent		10.7270/Q2PV6NDZ		aid1795419	US10059688	Hu, S; Liu, X; Bai, J; Long, W	8/28/2018	12/11/2018	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117800589	378152427							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511973	CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12	InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)	ZVDNYQWIKVDTKR-UHFFFAOYSA-N	270569	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-1::US10577352, Compound I-1	Epidermal growth factor receptor	Homo sapiens		 5.00					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270569&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213675	378152449							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511974	CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12	InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)	ZVDNYQWIKVDTKR-UHFFFAOYSA-N	270569	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-1::US10577352, Compound I-1	Epidermal growth factor receptor	Homo sapiens				 101			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270569&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213675	378152449							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511975	CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12	InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	ZVDNYQWIKVDTKR-QHCPKHFHSA-N	270570	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl)- N4- neopentylquinazoline- 4,6-diamine::US10059695, I-2::US10577352, Compound I-2	Epidermal growth factor receptor	Homo sapiens		 7.70					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270570&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213676	378152450							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511976	CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12	InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	ZVDNYQWIKVDTKR-QHCPKHFHSA-N	270570	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl)- N4- neopentylquinazoline- 4,6-diamine::US10059695, I-2::US10577352, Compound I-2	Epidermal growth factor receptor	Homo sapiens				 85.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270570&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213676	378152450							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511977	CC1(CNc2ncnc3ccc(NC(c4cn(nn4)C4CC4)c4ccc(F)cc4)cc23)CCOCC1	InChI=1S/C27H30FN7O/c1-27(10-12-36-13-11-27)16-29-26-22-14-20(6-9-23(22)30-17-31-26)32-25(18-2-4-19(28)5-3-18)24-15-35(34-33-24)21-7-8-21/h2-6,9,14-15,17,21,25,32H,7-8,10-13,16H2,1H3,(H,29,30,31)	CVDCGMIOVXHTCP-UHFFFAOYSA-N	270571	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4-((4- methyltetrahydro- 2H-pyran-4- yl)methyl)quinazoline- 4,6-diamine::US10059695, I-3::US10577352, Compound I-3	Epidermal growth factor receptor	Homo sapiens		 11.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270571&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213677	378152451							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511978	CC1(CNc2ncnc3ccc(NC(c4cn(nn4)C4CC4)c4ccc(F)cc4)cc23)CCOCC1	InChI=1S/C27H30FN7O/c1-27(10-12-36-13-11-27)16-29-26-22-14-20(6-9-23(22)30-17-31-26)32-25(18-2-4-19(28)5-3-18)24-15-35(34-33-24)21-7-8-21/h2-6,9,14-15,17,21,25,32H,7-8,10-13,16H2,1H3,(H,29,30,31)	CVDCGMIOVXHTCP-UHFFFAOYSA-N	270571	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4-((4- methyltetrahydro- 2H-pyran-4- yl)methyl)quinazoline- 4,6-diamine::US10059695, I-3::US10577352, Compound I-3	Epidermal growth factor receptor	Homo sapiens				 296			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270571&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213677	378152451							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511979	CC[C@@H](Nc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)c1ccccc1	InChI=1S/C29H28FN7/c1-2-25(19-6-4-3-5-7-19)34-29-24-16-22(12-15-26(24)31-18-32-29)33-28(20-8-10-21(30)11-9-20)27-17-37(36-35-27)23-13-14-23/h3-12,15-18,23,25,28,33H,2,13-14H2,1H3,(H,31,32,34)/t25-,28?/m1/s1	ZTUABMSJXUHFJK-RXVAYIKUSA-N	270572	N6-((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4-((R)-1- phenylpropyl) quinazoline- 4,6-diamine::US10059695, I-4::US10577352, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 43.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270572&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213678	378152452							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511980	CC[C@@H](Nc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)c1ccccc1	InChI=1S/C29H28FN7/c1-2-25(19-6-4-3-5-7-19)34-29-24-16-22(12-15-26(24)31-18-32-29)33-28(20-8-10-21(30)11-9-20)27-17-37(36-35-27)23-13-14-23/h3-12,15-18,23,25,28,33H,2,13-14H2,1H3,(H,31,32,34)/t25-,28?/m1/s1	ZTUABMSJXUHFJK-RXVAYIKUSA-N	270572	N6-((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4-((R)-1- phenylpropyl) quinazoline- 4,6-diamine::US10059695, I-4::US10577352, Compound I-4	Epidermal growth factor receptor	Homo sapiens				 796			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270572&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213678	378152452							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511981	Fc1ccc(cc1)C(Nc1ccc2ncnc(NC(CC#N)c3ccccc3)c2c1)c1cn(nn1)C1CC1	InChI=1S/C29H25FN8/c30-21-8-6-20(7-9-21)28(27-17-38(37-36-27)23-11-12-23)34-22-10-13-26-24(16-22)29(33-18-32-26)35-25(14-15-31)19-4-2-1-3-5-19/h1-10,13,16-18,23,25,28,34H,11-12,14H2,(H,32,33,35)	PMKQVHDRZZCGPS-UHFFFAOYSA-N	270573	3-((6-(((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)amino)quinazolin- 4-yl)amino)-3- phenylpropanenitrile::US10059695, I-5::US10577352, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 53.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270573&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213679	378152453							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511982	Fc1ccc(cc1)C(Nc1ccc2ncnc(NC(CC#N)c3ccccc3)c2c1)c1cn(nn1)C1CC1	InChI=1S/C29H25FN8/c30-21-8-6-20(7-9-21)28(27-17-38(37-36-27)23-11-12-23)34-22-10-13-26-24(16-22)29(33-18-32-26)35-25(14-15-31)19-4-2-1-3-5-19/h1-10,13,16-18,23,25,28,34H,11-12,14H2,(H,32,33,35)	PMKQVHDRZZCGPS-UHFFFAOYSA-N	270573	3-((6-(((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)amino)quinazolin- 4-yl)amino)-3- phenylpropanenitrile::US10059695, I-5::US10577352, Compound I-5	Epidermal growth factor receptor	Homo sapiens				 2503			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270573&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213679	378152453							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511983	[2H]C(N(CC)c1ccc2ncnc(NCC(C)(C)C)c2c1)(c1cn(nn1)C1CC1)c1ccc(F)cc1	InChI=1S/C27H32FN7/c1-5-34(21-12-13-23-22(14-21)26(31-17-30-23)29-16-27(2,3)4)25(18-6-8-19(28)9-7-18)24-15-35(33-32-24)20-10-11-20/h6-9,12-15,17,20,25H,5,10-11,16H2,1-4H3,(H,29,30,31)/t25-/m0/s1/i25D	BTTKRWWCCQEAES-QPTZSGNNSA-N	270574	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N6-ethyl-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-6	Epidermal growth factor receptor	Homo sapiens		 276					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270574&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213680	378152454							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511984	[2H]C(N(CC)c1ccc2ncnc(NCC(C)(C)C)c2c1)(c1cn(nn1)C1CC1)c1ccc(F)cc1	InChI=1S/C27H32FN7/c1-5-34(21-12-13-23-22(14-21)26(31-17-30-23)29-16-27(2,3)4)25(18-6-8-19(28)9-7-18)24-15-35(33-32-24)20-10-11-20/h6-9,12-15,17,20,25H,5,10-11,16H2,1-4H3,(H,29,30,31)/t25-/m0/s1/i25D	BTTKRWWCCQEAES-QPTZSGNNSA-N	270574	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N6-ethyl-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-6	Epidermal growth factor receptor	Homo sapiens				 4231			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270574&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213680	378152454							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511985	CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3cccc(c3)C#N)cc12	InChI=1S/C26H28N8/c1-26(2,3)15-28-25-21-12-19(7-10-22(21)29-16-30-25)31-24(18-6-4-5-17(11-18)13-27)23-14-34(33-32-23)20-8-9-20/h4-7,10-12,14,16,20,24,31H,8-9,15H2,1-3H3,(H,28,29,30)	HZPQSSSEUZOMMO-UHFFFAOYSA-N	270575	(S)-3-((1- cyclopropyl-1H- 1,2,3-triazol-4- yl)((4- (neopentylamino) quinazolin-6- yl)amino)methyl- d)benzonitrile::US10059695, I-7::US10577352, Compound I-7	Epidermal growth factor receptor	Homo sapiens		 2.60					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270575&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213681	378152455							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511986	CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3cccc(c3)C#N)cc12	InChI=1S/C26H28N8/c1-26(2,3)15-28-25-21-12-19(7-10-22(21)29-16-30-25)31-24(18-6-4-5-17(11-18)13-27)23-14-34(33-32-23)20-8-9-20/h4-7,10-12,14,16,20,24,31H,8-9,15H2,1-3H3,(H,28,29,30)	HZPQSSSEUZOMMO-UHFFFAOYSA-N	270575	(S)-3-((1- cyclopropyl-1H- 1,2,3-triazol-4- yl)((4- (neopentylamino) quinazolin-6- yl)amino)methyl- d)benzonitrile::US10059695, I-7::US10577352, Compound I-7	Epidermal growth factor receptor	Homo sapiens				 102			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270575&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213681	378152455							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511987	CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccccc3Cl)cc12	InChI=1S/C25H28ClN7/c1-25(2,3)14-27-24-19-12-16(8-11-21(19)28-15-29-24)30-23(18-6-4-5-7-20(18)26)22-13-33(32-31-22)17-9-10-17/h4-8,11-13,15,17,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	KKQZQORNQXJZDZ-QHCPKHFHSA-N	270576	(S)-N6-((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3-triazol-4- yl)methyl)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-8::US10577352, Compound I-8	Epidermal growth factor receptor	Homo sapiens		 13.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270576&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213682	378152456							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511988	CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccccc3Cl)cc12	InChI=1S/C25H28ClN7/c1-25(2,3)14-27-24-19-12-16(8-11-21(19)28-15-29-24)30-23(18-6-4-5-7-20(18)26)22-13-33(32-31-22)17-9-10-17/h4-8,11-13,15,17,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	KKQZQORNQXJZDZ-QHCPKHFHSA-N	270576	(S)-N6-((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3-triazol-4- yl)methyl)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-8::US10577352, Compound I-8	Epidermal growth factor receptor	Homo sapiens				 169			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270576&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213682	378152456							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511989	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12	InChI=1S/C25H27Cl2N7/c1-25(2,3)13-28-24-18-10-15(11-20(27)22(18)29-14-30-24)31-23(17-6-4-5-7-19(17)26)21-12-34(33-32-21)16-8-9-16/h4-7,10-12,14,16,23,31H,8-9,13H2,1-3H3,(H,28,29,30)	LHFXWQMDZTYDNH-UHFFFAOYSA-N	270577	(S)-8-chloro-N6-((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3-triazol-4- yl)methyl-d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-9::US10577352, Compound I-9	Epidermal growth factor receptor	Homo sapiens		 4.80					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270577&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213683	378152457							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511990	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12	InChI=1S/C25H27Cl2N7/c1-25(2,3)13-28-24-18-10-15(11-20(27)22(18)29-14-30-24)31-23(17-6-4-5-7-19(17)26)21-12-34(33-32-21)16-8-9-16/h4-7,10-12,14,16,23,31H,8-9,13H2,1-3H3,(H,28,29,30)	LHFXWQMDZTYDNH-UHFFFAOYSA-N	270577	(S)-8-chloro-N6-((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3-triazol-4- yl)methyl-d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-9::US10577352, Compound I-9	Epidermal growth factor receptor	Homo sapiens				 86.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270577&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213683	378152457							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511991	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(CC(O)=O)nn3)c3ccccc3Cl)cc12	InChI=1S/C24H25Cl2N7O2/c1-24(2,3)12-27-23-16-8-14(9-18(26)21(16)28-13-29-23)30-22(15-6-4-5-7-17(15)25)19-10-33(32-31-19)11-20(34)35/h4-10,13,22,30H,11-12H2,1-3H3,(H,34,35)(H,27,28,29)	HFRMICLFXNJUSQ-UHFFFAOYSA-N	270578	(S)-2-(4-(((8-chloro- 4- (neopentylamino) quinazolin-6- yl)amino)(2- chlorophenyl)methyl- d)-1H-1,2,3-triazol- 1-yl)acetic acid::US10059695, I-10::US10577352, Compound I-10	Epidermal growth factor receptor	Homo sapiens		 13.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270578&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213684	378152458							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511992	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(CC(O)=O)nn3)c3ccccc3Cl)cc12	InChI=1S/C24H25Cl2N7O2/c1-24(2,3)12-27-23-16-8-14(9-18(26)21(16)28-13-29-23)30-22(15-6-4-5-7-17(15)25)19-10-33(32-31-19)11-20(34)35/h4-10,13,22,30H,11-12H2,1-3H3,(H,34,35)(H,27,28,29)	HFRMICLFXNJUSQ-UHFFFAOYSA-N	270578	(S)-2-(4-(((8-chloro- 4- (neopentylamino) quinazolin-6- yl)amino)(2- chlorophenyl)methyl- d)-1H-1,2,3-triazol- 1-yl)acetic acid::US10059695, I-10::US10577352, Compound I-10	Epidermal growth factor receptor	Homo sapiens				>1000			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270578&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213684	378152458							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511993	Fc1ccc(cc1)C(Nc1cc(Cl)c2ncnc(N[C@H](CCC#N)c3ccccc3)c2c1)c1cn(nn1)C1CC1	InChI=1S/C30H26ClFN8/c31-25-16-22(36-28(20-8-10-21(32)11-9-20)27-17-40(39-38-27)23-12-13-23)15-24-29(25)34-18-35-30(24)37-26(7-4-14-33)19-5-2-1-3-6-19/h1-3,5-6,8-11,15-18,23,26,28,36H,4,7,12-13H2,(H,34,35,37)/t26-,28?/m1/s1	LMGXIJOACLYHHX-HSLSYKTRSA-N	270579	(R)-4-((8-chloro-6- (((S)-(1-cyclopropyl- 1H-1,2,3-triazol-4- yl)(4- fluorophenyl)methyl- d)amino)quinazolin- 4-yl)amino)-4- phenylbutanenitrile::US10059695, I-11::US10577352, Compound I-11	Epidermal growth factor receptor	Homo sapiens		 46.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270579&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213685	378152459							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511994	Fc1ccc(cc1)C(Nc1cc(Cl)c2ncnc(N[C@H](CCC#N)c3ccccc3)c2c1)c1cn(nn1)C1CC1	InChI=1S/C30H26ClFN8/c31-25-16-22(36-28(20-8-10-21(32)11-9-20)27-17-40(39-38-27)23-12-13-23)15-24-29(25)34-18-35-30(24)37-26(7-4-14-33)19-5-2-1-3-6-19/h1-3,5-6,8-11,15-18,23,26,28,36H,4,7,12-13H2,(H,34,35,37)/t26-,28?/m1/s1	LMGXIJOACLYHHX-HSLSYKTRSA-N	270579	(R)-4-((8-chloro-6- (((S)-(1-cyclopropyl- 1H-1,2,3-triazol-4- yl)(4- fluorophenyl)methyl- d)amino)quinazolin- 4-yl)amino)-4- phenylbutanenitrile::US10059695, I-11::US10577352, Compound I-11	Epidermal growth factor receptor	Homo sapiens				 671			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270579&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213685	378152459							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511995	Fc1ccc(cc1)C(Nc1cc(Cl)c2ncnc(N[C@H](CCC#N)c3ccccc3)c2c1)c1cn(nn1)C1(CC1)C(F)(F)F	InChI=1S/C31H25ClF4N8/c32-24-16-22(15-23-28(24)38-18-39-29(23)41-25(7-4-14-37)19-5-2-1-3-6-19)40-27(20-8-10-21(33)11-9-20)26-17-44(43-42-26)30(12-13-30)31(34,35)36/h1-3,5-6,8-11,15-18,25,27,40H,4,7,12-13H2,(H,38,39,41)/t25-,27?/m1/s1	QFUBYXGHFZTBLQ-CSMDKSQMSA-N	270580	(R)-4-((8-chloro-6- (((S)-(4- fluorophenyl)(1-(1- (trifluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl- d)amino)quinazolin- 4-yl)amino)-4- phenylbutanenitrile::US10059695, I-12::US10577352, Compound I-12	Epidermal growth factor receptor	Homo sapiens		 137					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270580&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213686	378152460							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511996	Fc1ccc(cc1)C(Nc1cc(Cl)c2ncnc(N[C@H](CCC#N)c3ccccc3)c2c1)c1cn(nn1)C1(CC1)C(F)(F)F	InChI=1S/C31H25ClF4N8/c32-24-16-22(15-23-28(24)38-18-39-29(23)41-25(7-4-14-37)19-5-2-1-3-6-19)40-27(20-8-10-21(33)11-9-20)26-17-44(43-42-26)30(12-13-30)31(34,35)36/h1-3,5-6,8-11,15-18,25,27,40H,4,7,12-13H2,(H,38,39,41)/t25-,27?/m1/s1	QFUBYXGHFZTBLQ-CSMDKSQMSA-N	270580	(R)-4-((8-chloro-6- (((S)-(4- fluorophenyl)(1-(1- (trifluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl- d)amino)quinazolin- 4-yl)amino)-4- phenylbutanenitrile::US10059695, I-12::US10577352, Compound I-12	Epidermal growth factor receptor	Homo sapiens				>1000			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270580&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213686	378152460							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511997	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CC3)C(F)(F)F)c3ccc(F)cc3)cc12	InChI=1S/C26H26ClF4N7/c1-24(2,3)13-32-23-18-10-17(11-19(27)22(18)33-14-34-23)35-21(15-4-6-16(28)7-5-15)20-12-38(37-36-20)25(8-9-25)26(29,30)31/h4-7,10-12,14,21,35H,8-9,13H2,1-3H3,(H,32,33,34)	XAGDHJYRYPWUNB-UHFFFAOYSA-N	270581	(S)-8-chloro-N6-((4- fluorophenyl)(1-(1- (trifluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-13::US10577352, Compound I-13	Epidermal growth factor receptor	Homo sapiens		 10.00					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270581&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213687	378152461							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511998	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CC3)C(F)(F)F)c3ccc(F)cc3)cc12	InChI=1S/C26H26ClF4N7/c1-24(2,3)13-32-23-18-10-17(11-19(27)22(18)33-14-34-23)35-21(15-4-6-16(28)7-5-15)20-12-38(37-36-20)25(8-9-25)26(29,30)31/h4-7,10-12,14,21,35H,8-9,13H2,1-3H3,(H,32,33,34)	XAGDHJYRYPWUNB-UHFFFAOYSA-N	270581	(S)-8-chloro-N6-((4- fluorophenyl)(1-(1- (trifluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-13::US10577352, Compound I-13	Epidermal growth factor receptor	Homo sapiens				 181			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270581&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213687	378152461							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
511999	CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)C#N	InChI=1S/C26H27FN8/c1-26(2,3)14-29-25-21-11-19(10-17(12-28)23(21)30-15-31-25)32-24(16-4-6-18(27)7-5-16)22-13-35(34-33-22)20-8-9-20/h4-7,10-11,13,15,20,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	ZEUWUUJAEHFIQN-UHFFFAOYSA-N	270582	(S)-6-(((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)amino)-4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-14::US10577352, Compound I-14	Epidermal growth factor receptor	Homo sapiens		 2.10					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270582&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213688	378152462							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512000	CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)C#N	InChI=1S/C26H27FN8/c1-26(2,3)14-29-25-21-11-19(10-17(12-28)23(21)30-15-31-25)32-24(16-4-6-18(27)7-5-16)22-13-35(34-33-22)20-8-9-20/h4-7,10-11,13,15,20,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	ZEUWUUJAEHFIQN-UHFFFAOYSA-N	270582	(S)-6-(((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)amino)-4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-14::US10577352, Compound I-14	Epidermal growth factor receptor	Homo sapiens				 42.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270582&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213688	378152462							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512001	CC(C)(C)CNc1ncnc2c(Br)cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12	InChI=1S/C25H27BrFN7/c1-25(2,3)13-28-24-19-10-17(11-20(26)23(19)29-14-30-24)31-22(15-4-6-16(27)7-5-15)21-12-34(33-32-21)18-8-9-18/h4-7,10-12,14,18,22,31H,8-9,13H2,1-3H3,(H,28,29,30)	QMMYRSWUMOZVFJ-UHFFFAOYSA-N	270583	(S)-8-bromo-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-15::US10577352, Compound I-15	Epidermal growth factor receptor	Homo sapiens		 2.60					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270583&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213689	378152463							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512002	CC(C)(C)CNc1ncnc2c(Br)cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12	InChI=1S/C25H27BrFN7/c1-25(2,3)13-28-24-19-10-17(11-20(26)23(19)29-14-30-24)31-22(15-4-6-16(27)7-5-15)21-12-34(33-32-21)18-8-9-18/h4-7,10-12,14,18,22,31H,8-9,13H2,1-3H3,(H,28,29,30)	QMMYRSWUMOZVFJ-UHFFFAOYSA-N	270583	(S)-8-bromo-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-15::US10577352, Compound I-15	Epidermal growth factor receptor	Homo sapiens				 82.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270583&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213689	378152463							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512003	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CF)CC3)c3ccc(F)cc3)cc12	InChI=1S/C26H28ClF2N7/c1-25(2,3)14-30-24-19-10-18(11-20(27)23(19)31-15-32-24)33-22(16-4-6-17(29)7-5-16)21-12-36(35-34-21)26(13-28)8-9-26/h4-7,10-12,15,22,33H,8-9,13-14H2,1-3H3,(H,30,31,32)	DKVMOUAUMOHCGA-UHFFFAOYSA-N	270584	(S)-8-chloro-N6-((1- (1- (fluoromethyl) cyclopropyl)-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-16::US10577352, Compound I-16	Epidermal growth factor receptor	Homo sapiens		 3.10					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270584&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213690	378152464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512004	CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CF)CC3)c3ccc(F)cc3)cc12	InChI=1S/C26H28ClF2N7/c1-25(2,3)14-30-24-19-10-18(11-20(27)23(19)31-15-32-24)33-22(16-4-6-17(29)7-5-16)21-12-36(35-34-21)26(13-28)8-9-26/h4-7,10-12,15,22,33H,8-9,13-14H2,1-3H3,(H,30,31,32)	DKVMOUAUMOHCGA-UHFFFAOYSA-N	270584	(S)-8-chloro-N6-((1- (1- (fluoromethyl) cyclopropyl)-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-16::US10577352, Compound I-16	Epidermal growth factor receptor	Homo sapiens				 46.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270584&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213690	378152464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512005	CC(C)(C)CNc1ncnc2c(cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12)C#N	InChI=1S/C28H26F3N9S/c1-26(2,3)13-33-25-19-10-17(9-16(11-32)22(19)34-14-35-25)37-23(18-5-4-6-20-24(18)41-15-36-20)21-12-40(39-38-21)27(7-8-27)28(29,30)31/h4-6,9-10,12,14-15,23,37H,7-8,13H2,1-3H3,(H,33,34,35)/t23-/m0/s1	DXFKFNWGYXPFEX-QHCPKHFHSA-N	270585	(S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromethyl) cyclopropyl)-1H- 1,2,3-triazol-4- yl)methyl)amino)-4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-17::US10577352, Compound I-17	Epidermal growth factor receptor	Homo sapiens		 3.30					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270585&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213691	378152465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512006	CC(C)(C)CNc1ncnc2c(cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12)C#N	InChI=1S/C28H26F3N9S/c1-26(2,3)13-33-25-19-10-17(9-16(11-32)22(19)34-14-35-25)37-23(18-5-4-6-20-24(18)41-15-36-20)21-12-40(39-38-21)27(7-8-27)28(29,30)31/h4-6,9-10,12,14-15,23,37H,7-8,13H2,1-3H3,(H,33,34,35)/t23-/m0/s1	DXFKFNWGYXPFEX-QHCPKHFHSA-N	270585	(S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromethyl) cyclopropyl)-1H- 1,2,3-triazol-4- yl)methyl)amino)-4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-17::US10577352, Compound I-17	Epidermal growth factor receptor	Homo sapiens				 59.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270585&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213691	378152465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512007	CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12	InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	LWKBAGGIOZPLOK-QFIPXVFZSA-N	270586	(S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl)- 8-bromo-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-18::US10577352, Compound I-18	Epidermal growth factor receptor	Homo sapiens		 8.00					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270586&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213692	378152466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512008	CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12	InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	LWKBAGGIOZPLOK-QFIPXVFZSA-N	270586	(S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl)- 8-bromo-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-18::US10577352, Compound I-18	Epidermal growth factor receptor	Homo sapiens				 195			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270586&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213692	378152466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512009	CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12)C#N	InChI=1S/C26H27ClN8/c1-26(2,3)14-29-25-20-11-17(10-16(12-28)23(20)30-15-31-25)32-24(19-6-4-5-7-21(19)27)22-13-35(34-33-22)18-8-9-18/h4-7,10-11,13,15,18,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	QUJUDJTWSXMGFT-UHFFFAOYSA-N	270587	(S)-6-(((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3-triazol-4- yl)methyl-d)amino)- 4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-19::US10577352, Compound I-19	Epidermal growth factor receptor	Homo sapiens		 2.40					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270587&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213693	378152467							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512010	CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12)C#N	InChI=1S/C26H27ClN8/c1-26(2,3)14-29-25-20-11-17(10-16(12-28)23(20)30-15-31-25)32-24(19-6-4-5-7-21(19)27)22-13-35(34-33-22)18-8-9-18/h4-7,10-11,13,15,18,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	QUJUDJTWSXMGFT-UHFFFAOYSA-N	270587	(S)-6-(((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3-triazol-4- yl)methyl-d)amino)- 4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-19::US10577352, Compound I-19	Epidermal growth factor receptor	Homo sapiens				 20.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270587&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213693	378152467							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512011	CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3(CC3)C#N)c3ccccc3Cl)cc12)C#N	InChI=1S/C27H26ClN9/c1-26(2,3)15-31-25-20-11-18(10-17(12-29)23(20)32-16-33-25)34-24(19-6-4-5-7-21(19)28)22-13-37(36-35-22)27(14-30)8-9-27/h4-7,10-11,13,16,24,34H,8-9,15H2,1-3H3,(H,31,32,33)	ILAHDUGQOPPNDT-UHFFFAOYSA-N	270588	(S)-6-(((2- chlorophenyl)(1-(1- cyanocyclopropyl)- 1H-1,2,3-triazol-4- yl)methyl-d)amino)- 4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-20::US10577352, Compound I-20	Epidermal growth factor receptor	Homo sapiens		 3.30					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270588&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213694	378152468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512012	CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3(CC3)C#N)c3ccccc3Cl)cc12)C#N	InChI=1S/C27H26ClN9/c1-26(2,3)15-31-25-20-11-18(10-17(12-29)23(20)32-16-33-25)34-24(19-6-4-5-7-21(19)28)22-13-37(36-35-22)27(14-30)8-9-27/h4-7,10-11,13,16,24,34H,8-9,15H2,1-3H3,(H,31,32,33)	ILAHDUGQOPPNDT-UHFFFAOYSA-N	270588	(S)-6-(((2- chlorophenyl)(1-(1- cyanocyclopropyl)- 1H-1,2,3-triazol-4- yl)methyl-d)amino)- 4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-20::US10577352, Compound I-20	Epidermal growth factor receptor	Homo sapiens				 35.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270588&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213694	378152468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512013	Cc1nc(F)ccc1[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C26H28ClF3N8/c1-14-16(5-6-20(28)34-14)22(19-11-38(37-36-19)26(7-8-26)24(29)30)35-15-9-17-21(18(27)10-15)32-13-33-23(17)31-12-25(2,3)4/h5-6,9-11,13,22,24,35H,7-8,12H2,1-4H3,(H,31,32,33)/t22-/m0/s1	SJEHYXHKSZJDSU-QFIPXVFZSA-N	270589	(S)-8-chloro-N6-((1- (1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)(6- fluoro-2- melhylpyridin-3- yl)methyl)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-21::US10577352, Compound I-21	Epidermal growth factor receptor	Homo sapiens		 1.90					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270589&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213695	378152469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512014	Cc1nc(F)ccc1[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C26H28ClF3N8/c1-14-16(5-6-20(28)34-14)22(19-11-38(37-36-19)26(7-8-26)24(29)30)35-15-9-17-21(18(27)10-15)32-13-33-23(17)31-12-25(2,3)4/h5-6,9-11,13,22,24,35H,7-8,12H2,1-4H3,(H,31,32,33)/t22-/m0/s1	SJEHYXHKSZJDSU-QFIPXVFZSA-N	270589	(S)-8-chloro-N6-((1- (1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)(6- fluoro-2- melhylpyridin-3- yl)methyl)-N4- neopentylquinazoline- 4,6-diamine::US10059695, I-21::US10577352, Compound I-21	Epidermal growth factor receptor	Homo sapiens				 28.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270589&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213695	378152469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512015	Cc1nc(F)ccc1[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C27H28F3N9/c1-15-18(5-6-21(28)35-15)23(20-12-39(38-37-20)27(7-8-27)25(29)30)36-17-9-16(11-31)22-19(10-17)24(34-14-33-22)32-13-26(2,3)4/h5-6,9-10,12,14,23,25,36H,7-8,13H2,1-4H3,(H,32,33,34)/t23-/m0/s1	XDFIDZUAPHHWSG-QHCPKHFHSA-N	270590	(S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)(6- fluoro-2- methylpyridin-3- yl)methyl)amino)-4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-22::US10577352, Compound I-22	Epidermal growth factor receptor	Homo sapiens		 1.70					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270590&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213696	378152470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512016	Cc1nc(F)ccc1[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C27H28F3N9/c1-15-18(5-6-21(28)35-15)23(20-12-39(38-37-20)27(7-8-27)25(29)30)36-17-9-16(11-31)22-19(10-17)24(34-14-33-22)32-13-26(2,3)4/h5-6,9-10,12,14,23,25,36H,7-8,13H2,1-4H3,(H,32,33,34)/t23-/m0/s1	XDFIDZUAPHHWSG-QHCPKHFHSA-N	270590	(S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)(6- fluoro-2- methylpyridin-3- yl)methyl)amino)-4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-22::US10577352, Compound I-22	Epidermal growth factor receptor	Homo sapiens				 36.0			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270590&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213696	378152470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512017	Cc1c(cccc1[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F)C#N	InChI=1S/C28H29ClF2N8/c1-16-17(12-32)6-5-7-19(16)24(22-13-39(38-37-22)28(8-9-28)26(30)31)36-18-10-20-23(21(29)11-18)34-15-35-25(20)33-14-27(2,3)4/h5-7,10-11,13,15,24,26,36H,8-9,14H2,1-4H3,(H,33,34,35)/t24-/m0/s1	QXZJAIOJWURBOH-DEOSSOPVSA-N	270591	(S)-3-(((8-chloro-4- (neopentylamino) quinazolin-6- yl)amino)(1-(1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl)- 2-methylbenzonitrile::US10059695, I-23::US10577352, Compound I-23	Epidermal growth factor receptor	Homo sapiens		 1.60					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270591&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213697	378152471							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512018	Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	ZLTUHAMWJNCZRE-SANMLTNESA-N	270592	(S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)(2- methyl-1-oxo-1,2- dihydroisoquinolin- 5-yl)methyl)amino)- 4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-24::US10577352, Compound I-24	Epidermal growth factor receptor	Homo sapiens		 1.20					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270592&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213698	378152472							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512019	Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	ZLTUHAMWJNCZRE-SANMLTNESA-N	270592	(S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)(2- methyl-1-oxo-1,2- dihydroisoquinolin- 5-yl)methyl)amino)- 4- (neopentylamino) quinazoline-8- carbonitrile::US10059695, I-24::US10577352, Compound I-24	Epidermal growth factor receptor	Homo sapiens				 11.3			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270592&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213698	378152472							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512020	Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C30H31ClF2N8O/c1-29(2,3)15-34-26-21-12-17(13-22(31)24(21)35-16-36-26)37-25(23-14-41(39-38-23)30(9-10-30)28(32)33)19-6-5-7-20-18(19)8-11-40(4)27(20)42/h5-8,11-14,16,25,28,37H,9-10,15H2,1-4H3,(H,34,35,36)/t25-/m0/s1	GEKGVRGEWWWLHR-VWLOTQADSA-N	270593	(S)-5-(((8-chloro-4- (neopentylamino) quinazolin-6- yl)amino)(1-(1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl)- 2-methylisoquinolin- 1(2H)-one::US10059695, I-25::US10577352, Compound I-25	Epidermal growth factor receptor	Homo sapiens		 2.40					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270593&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213699	378152473							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512021	Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F	InChI=1S/C30H31ClF2N8O/c1-29(2,3)15-34-26-21-12-17(13-22(31)24(21)35-16-36-26)37-25(23-14-41(39-38-23)30(9-10-30)28(32)33)19-6-5-7-20-18(19)8-11-40(4)27(20)42/h5-8,11-14,16,25,28,37H,9-10,15H2,1-4H3,(H,34,35,36)/t25-/m0/s1	GEKGVRGEWWWLHR-VWLOTQADSA-N	270593	(S)-5-(((8-chloro-4- (neopentylamino) quinazolin-6- yl)amino)(1-(1- (difluoromethyl) cyclopropyl)-1H-1,2,3- triazol-4-yl)methyl)- 2-methylisoquinolin- 1(2H)-one::US10059695, I-25::US10577352, Compound I-25	Epidermal growth factor receptor	Homo sapiens				 25.5			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270593&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213699	378152473							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512022	Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C12CC(C1)C2	InChI=1S/C31H33ClN8O/c1-30(2,3)16-33-28-23-10-19(11-24(32)26(23)34-17-35-28)36-27(25-15-40(38-37-25)31-12-18(13-31)14-31)21-6-5-7-22-20(21)8-9-39(4)29(22)41/h5-11,15,17-18,27,36H,12-14,16H2,1-4H3,(H,33,34,35)/t18?,27-,31?/m0/s1	AKINQEJPDZMCSD-MLCRSYRFSA-N	270594	(S)-5-((1- (bicyclo[1.1.1]pentan- 1-yl)-1H-1,2,3- triazol-4-yl)((8- chloro-4- (neopentylamino) quinazolin-6- yl)amino)methyl)-2- methylisoquinolin- 1(2H)-one::US10059695, I-27::US10577352, Compound I-27	Epidermal growth factor receptor	Homo sapiens		 1.70					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270594&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213700	378152474							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512023	Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C12CC(C1)C2	InChI=1S/C31H33ClN8O/c1-30(2,3)16-33-28-23-10-19(11-24(32)26(23)34-17-35-28)36-27(25-15-40(38-37-25)31-12-18(13-31)14-31)21-6-5-7-22-20(21)8-9-39(4)29(22)41/h5-11,15,17-18,27,36H,12-14,16H2,1-4H3,(H,33,34,35)/t18?,27-,31?/m0/s1	AKINQEJPDZMCSD-MLCRSYRFSA-N	270594	(S)-5-((1- (bicyclo[1.1.1]pentan- 1-yl)-1H-1,2,3- triazol-4-yl)((8- chloro-4- (neopentylamino) quinazolin-6- yl)amino)methyl)-2- methylisoquinolin- 1(2H)-one::US10059695, I-27::US10577352, Compound I-27	Epidermal growth factor receptor	Homo sapiens				 12.1			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270594&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213700	378152474							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512024	Fc1ccc(Nc2ncnc3c(Cl)cc(NC(c4cn(nn4)C4CCN(CC4)C(=O)OCc4ccccc4)c4ccccc4)cc23)cc1Cl	InChI=1S/C36H31Cl2FN8O2/c37-29-18-25(11-12-31(29)39)43-35-28-17-26(19-30(38)34(28)40-22-41-35)42-33(24-9-5-2-6-10-24)32-20-47(45-44-32)27-13-15-46(16-14-27)36(48)49-21-23-7-3-1-4-8-23/h1-12,17-20,22,27,33,42H,13-16,21H2,(H,40,41,43)	GGYCDQCSXUHDEN-UHFFFAOYSA-N	270595	US10059695, II-1::US10577352, Compound II-1::benzyl 4-(4-(((8- chloro-4-((3-chloro- 4- fluorophenyl)amino) quinazolin-6- yl)amino)(phenyl) methyl)-1H-1,2,3- triazol-1- yl)piperidine-1- carboxylate	Epidermal growth factor receptor	Homo sapiens		 8480					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270595&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213701	378152475							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512025	Fc1ccc(Nc2ncnc3c(Cl)cc(NC(c4cn(nn4)C4CCNCC4)c4ccccc4)cc23)cc1Cl	InChI=1S/C28H25Cl2FN8/c29-22-13-18(6-7-24(22)31)36-28-21-12-19(14-23(30)27(21)33-16-34-28)35-26(17-4-2-1-3-5-17)25-15-39(38-37-25)20-8-10-32-11-9-20/h1-7,12-16,20,26,32,35H,8-11H2,(H,33,34,36)	KZHPXNUBBKSPPG-UHFFFAOYSA-N	270596	8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- (phenyl(1-(piperidin- 4-yl)-1H-1,2,3- triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-2::US10577352, Compound II-2	Epidermal growth factor receptor	Homo sapiens		 28.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270596&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213702	378152476							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512026	CCN1CCC(CC1)n1cc(nn1)C(Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccccc1	InChI=1S/C30H29Cl2FN8/c1-2-40-12-10-22(11-13-40)41-17-27(38-39-41)28(19-6-4-3-5-7-19)36-21-14-23-29(25(32)16-21)34-18-35-30(23)37-20-8-9-26(33)24(31)15-20/h3-9,14-18,22,28,36H,2,10-13H2,1H3,(H,34,35,37)	BGNGGPVTCBTSPQ-UHFFFAOYSA-N	270597	8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((1-(1- ethylpiperidin-4-yl)- 1H-1,2,3-triazol-4- yl)(phenyl)methyl) quinazoline-4,6- diamine::US10059695, II-3::US10577352, Compound II-3	Epidermal growth factor receptor	Homo sapiens		 19.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270597&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213703	378152477							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512027	CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccccc1	InChI=1S/C30H29Cl2FN8/c1-2-40-12-10-22(11-13-40)41-17-27(38-39-41)28(19-6-4-3-5-7-19)36-21-14-23-29(25(32)16-21)34-18-35-30(23)37-20-8-9-26(33)24(31)15-20/h3-9,14-18,22,28,36H,2,10-13H2,1H3,(H,34,35,37)/t28-/m0/s1	BGNGGPVTCBTSPQ-NDEPHWFRSA-N	270598	(S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((1-(1- ethylpiperidin-4-yl)- 1H-1,2,3-triazol-4- yl)(phenyl)methyl) quinazoline-4,6- diamine::US10059695, II-4::US10577352, Compound II-4	Epidermal growth factor receptor	Homo sapiens		 5.90					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270598&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213704	378152478							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512028	CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccccc1	InChI=1S/C30H29Cl2FN8/c1-2-40-12-10-22(11-13-40)41-17-27(38-39-41)28(19-6-4-3-5-7-19)36-21-14-23-29(25(32)16-21)34-18-35-30(23)37-20-8-9-26(33)24(31)15-20/h3-9,14-18,22,28,36H,2,10-13H2,1H3,(H,34,35,37)/t28-/m0/s1	BGNGGPVTCBTSPQ-NDEPHWFRSA-N	270598	(S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((1-(1- ethylpiperidin-4-yl)- 1H-1,2,3-triazol-4- yl)(phenyl)methyl) quinazoline-4,6- diamine::US10059695, II-4::US10577352, Compound II-4	Epidermal growth factor receptor	Homo sapiens				 254			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270598&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213704	378152478							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512029	CC(C)(C)N1CCC(CC1)n1cc(nn1)[C@@H](Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1	InChI=1S/C32H33Cl2FN8/c1-32(2,3)42-14-12-24(13-15-42)43-18-29(40-41-43)30(20-4-6-21(33)7-5-20)38-22-9-11-28-25(16-22)31(37-19-36-28)39-23-8-10-27(35)26(34)17-23/h4-11,16-19,24,30,38H,12-15H2,1-3H3,(H,36,37,39)/t30-/m0/s1	UMZDDZPSFCBSGA-PMERELPUSA-N	270599	(S)-N6-((1-(1-(tert- butyl)piperidin-4- yl)-1H-1,2,3-triazol- 4-yl)(4- chlorophenyl) methyl)-N4-(3- chloro-4- fluorophenyl) quinazoline- 4,6-diamine::US10059695, II-5::US10577352, Compound II-5	Epidermal growth factor receptor	Homo sapiens		 72.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270599&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213705	378152479							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512030	Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4CCNCC4)c4ccc(Cl)cc4)cc23)cc1Cl	InChI=1S/C28H25Cl2FN8/c29-18-3-1-17(2-4-18)27(26-15-39(38-37-26)21-9-11-32-12-10-21)35-19-6-8-25-22(13-19)28(34-16-33-25)36-20-5-7-24(31)23(30)14-20/h1-8,13-16,21,27,32,35H,9-12H2,(H,33,34,36)/t27-/m0/s1	TZWDKKCSGGQCCI-MHZLTWQESA-N	270600	(S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chlorophenyl)(1- (piperidin-4-yl)-1H- 1,2,3-triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-6::US10577352, Compound II-6	Epidermal growth factor receptor	Homo sapiens		 49.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270600&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213706	378152480							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512031	Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl	InChI=1S/C26H20Cl2FN7O/c27-16-3-1-15(2-4-16)25(24-11-36(35-34-24)19-12-37-13-19)32-17-6-8-23-20(9-17)26(31-14-30-23)33-18-5-7-22(29)21(28)10-18/h1-11,14,19,25,32H,12-13H2,(H,30,31,33)/t25-/m0/s1	TUXTUSCLXYRBTM-VWLOTQADSA-N	270601	(S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chlorophenyl)(1- (oxetan-3-yl)-1H- 1,2,3-triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-7::US10577352, Compound II-7	Epidermal growth factor receptor	Homo sapiens		 284					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270601&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213707	378152481							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512032	Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4CCN(CC4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl	InChI=1S/C31H29Cl2FN8O/c32-20-3-1-19(2-4-20)30(29-15-42(40-39-29)23-9-11-41(12-10-23)24-16-43-17-24)37-21-6-8-28-25(13-21)31(36-18-35-28)38-22-5-7-27(34)26(33)14-22/h1-8,13-15,18,23-24,30,37H,9-12,16-17H2,(H,35,36,38)/t30-/m0/s1	YLLXLXBKQWDCEB-PMERELPUSA-N	270602	(S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chlorophenyl)(1- (1-(oxetan-3- yl)piperidin-4-yl)- 1H-1,2,3-triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-8::US10577352, Compound II-8	Epidermal growth factor receptor	Homo sapiens		 318					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270602&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213708	378152482							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512033	Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4CCN(CC4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl	InChI=1S/C31H29Cl2FN8O/c32-20-3-1-19(2-4-20)30(29-15-42(40-39-29)23-9-11-41(12-10-23)24-16-43-17-24)37-21-6-8-28-25(13-21)31(36-18-35-28)38-22-5-7-27(34)26(33)14-22/h1-8,13-15,18,23-24,30,37H,9-12,16-17H2,(H,35,36,38)/t30-/m0/s1	YLLXLXBKQWDCEB-PMERELPUSA-N	270602	(S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chlorophenyl)(1- (1-(oxetan-3- yl)piperidin-4-yl)- 1H-1,2,3-triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-8::US10577352, Compound II-8	Epidermal growth factor receptor	Homo sapiens				 1238			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270602&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213708	378152482							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512034	Fc1ccc(Nc2ncnc3c(Cl)cc(N[C@H](c4cn(nn4)C4CCNCC4)c4ccccc4)cc23)cc1Cl	InChI=1S/C28H25Cl2FN8/c29-22-13-18(6-7-24(22)31)36-28-21-12-19(14-23(30)27(21)33-16-34-28)35-26(17-4-2-1-3-5-17)25-15-39(38-37-25)20-8-10-32-11-9-20/h1-7,12-16,20,26,32,35H,8-11H2,(H,33,34,36)/t26-/m0/s1	KZHPXNUBBKSPPG-SANMLTNESA-N	270603	(S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- (phenyl(1-(piperidin- 4-yl)-1H-1,2,3- triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-9::US10577352, Compound II-9	Epidermal growth factor receptor	Homo sapiens		 8.30					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270603&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213709	378152483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512035	Fc1ccc(Nc2ncnc3c(Cl)cc(N[C@H](c4cn(nn4)C4CCNCC4)c4ccccc4)cc23)cc1Cl	InChI=1S/C28H25Cl2FN8/c29-22-13-18(6-7-24(22)31)36-28-21-12-19(14-23(30)27(21)33-16-34-28)35-26(17-4-2-1-3-5-17)25-15-39(38-37-25)20-8-10-32-11-9-20/h1-7,12-16,20,26,32,35H,8-11H2,(H,33,34,36)/t26-/m0/s1	KZHPXNUBBKSPPG-SANMLTNESA-N	270603	(S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- (phenyl(1-(piperidin- 4-yl)-1H-1,2,3- triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-9::US10577352, Compound II-9	Epidermal growth factor receptor	Homo sapiens				 337			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270603&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213709	378152483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512036	CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1	InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	YAKSRXYLNOGMCE-NDEPHWFRSA-N	270604	(S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((4-chlorophenyl)(1- (1-ethylpiperidin-4- yl)-1H-1,2,3-triazol- 4-yl)methyl) quinazoline- 4,6-diamine::US10059695, II-10::US10577352, Compound II-10	Epidermal growth factor receptor	Homo sapiens		 17.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270604&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213710	378152484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512037	CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1	InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	YAKSRXYLNOGMCE-NDEPHWFRSA-N	270604	(S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((4-chlorophenyl)(1- (1-ethylpiperidin-4- yl)-1H-1,2,3-triazol- 4-yl)methyl) quinazoline- 4,6-diamine::US10059695, II-10::US10577352, Compound II-10	Epidermal growth factor receptor	Homo sapiens				 527			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270604&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213710	378152484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512038	Fc1ccc(cc1)C(Nc1ccc2ncnc(Nc3cnc(F)c(F)c3)c2c1)c1cn(nn1)C1CC1	InChI=1S/C25H19F3N8/c26-15-3-1-14(2-4-15)23(22-12-36(35-34-22)18-6-7-18)32-16-5-8-21-19(9-16)25(31-13-30-21)33-17-10-20(27)24(28)29-11-17/h1-5,8-13,18,23,32H,6-7H2,(H,30,31,33)	CAEMCCZMBSKRRO-UHFFFAOYSA-N	270605	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4-(5,6- difluoropyridin-3- yl)quinazoline-4,6- diamine::US10059695, II-11::US10577352, Compound II-11	Epidermal growth factor receptor	Homo sapiens		 74.0					7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270605&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213711	378152485							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
512039	Fc1ccc(cc1)C(Nc1ccc2ncnc(Nc3cnc(F)c(F)c3)c2c1)c1cn(nn1)C1CC1	InChI=1S/C25H19F3N8/c26-15-3-1-14(2-4-15)23(22-12-36(35-34-22)18-6-7-18)32-16-5-8-21-19(9-16)25(31-13-30-21)33-17-10-20(27)24(28)29-11-17/h1-5,8-13,18,23,32H,6-7H2,(H,30,31,33)	CAEMCCZMBSKRRO-UHFFFAOYSA-N	270605	(S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N4-(5,6- difluoropyridin-3- yl)quinazoline-4,6- diamine::US10059695, II-11::US10577352, Compound II-11	Epidermal growth factor receptor	Homo sapiens				 645			7	25.00 C	US Patent		10.7270/Q2FB54Z6		aid1795424	US10059695	Balan, G; Chou, C; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Saito, RD; Squires, NH; Taylor, JG; Watkins, WJ; Wright, NE	8/28/2018	12/11/2018	Gilead Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270605&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			136213711	378152485							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544627	COc1ccccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H18F3N5O2/c1-3-18(30)26-13-7-6-8-14(11-13)27-19-15(21(22,23)24)12-25-20(29-19)28-16-9-4-5-10-17(16)31-2/h3-12H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	ARSGAAANDMOADX-UHFFFAOYSA-N	202369	US9238629, I-1::US10081606, Compound I-1::US9765038, Compound I-1	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56965025	319495463							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544629	COc1ccccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H17F3N4O3/c1-3-18(29)26-13-7-6-8-14(11-13)31-19-15(21(22,23)24)12-25-20(28-19)27-16-9-4-5-10-17(16)30-2/h3-12H,1H2,2H3,(H,26,29)(H,25,27,28)	KGGXRCWBXUHQBM-UHFFFAOYSA-N	202370	US9238629, I-2::US10081606, Compound I-2::US9765038, Compound I-2	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336077	319495464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544631	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H20F3N5O3/c1-4-19(31)27-13-6-5-7-14(10-13)28-20-16(22(23,24)25)12-26-21(30-20)29-17-9-8-15(32-2)11-18(17)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	ARWJHMPQGVRJGR-UHFFFAOYSA-N	202371	US9238629, I-3::US10081606, Compound I-3::US9765038, Compound I-3	Epidermal growth factor receptor	Human		 20.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336078	319495465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544633	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22ClN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	AWLYEWOENDLBPJ-UHFFFAOYSA-N	202372	US9238629, I-4::US10081606, Compound I-4::US9765038, Compound I-4	Epidermal growth factor receptor	Human		 65.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336218	319495466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544635	COc1ccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22BrN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	UKFLBAQMJNODAB-UHFFFAOYSA-N	202373	US9238629, I-5::US10081606, Compound I-5::US9765038, Compound I-5	Epidermal growth factor receptor	Human		 65.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336219	319495467							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544637	COc1cccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H19BrN4O4/c1-4-18(27)24-13-7-5-8-14(11-13)30-20-15(22)12-23-21(26-20)25-16-9-6-10-17(28-2)19(16)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	MOQWLDSTRHMSCL-UHFFFAOYSA-N	202374	US9238629, I-14::US9238629, I-6::US10081606, Compound I-6::US9765038, Compound I-6	Epidermal growth factor receptor	Human		 650					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336220	319495468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544639	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21ClN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	KKXHOHZIJWZIMH-UHFFFAOYSA-N	202375	US9238629, I-7::US10081606, Compound I-7::US9765038, Compound I-7	Epidermal growth factor receptor	Human		 20.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336221	319495469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544641	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21BrN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	YVPOPEGFKSLPQP-UHFFFAOYSA-N	202376	US9238629, I-8::US10081606, Compound I-8::US9765038, Compound I-8	Epidermal growth factor receptor	Human		 65.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336222	319495470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544643	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H19F3N4O4/c1-4-19(30)27-13-6-5-7-15(10-13)33-20-16(22(23,24)25)12-26-21(29-20)28-17-9-8-14(31-2)11-18(17)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	YQRLADVWFUXYQX-UHFFFAOYSA-N	202377	US9238629, I-9::US10081606, Compound I-9::US9765038, Compound I-9	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336223	319495471							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544645	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H21F3N4O5/c1-5-18(31)28-13-7-6-8-14(11-13)35-21-15(23(24,25)26)12-27-22(30-21)29-16-9-10-17(32-2)20(34-4)19(16)33-3/h5-12H,1H2,2-4H3,(H,28,31)(H,27,29,30)	BJXUJZVUNLHQJX-UHFFFAOYSA-N	202378	US9238629, I-10::US10081606, Compound I-10::US9765038, Compound I-10	Epidermal growth factor receptor	Human		 65.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202378&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333995	319495472							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544647	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H22F3N5O4/c1-5-18(32)28-13-7-6-8-14(11-13)29-21-15(23(24,25)26)12-27-22(31-21)30-16-9-10-17(33-2)20(35-4)19(16)34-3/h5-12H,1H2,2-4H3,(H,28,32)(H2,27,29,30,31)	XTEXGVCQXOYDOW-UHFFFAOYSA-N	202379	US9238629, I-11::US10081606, Compound I-11::US9765038, Compound I-11	Epidermal growth factor receptor	Human		 20.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333996	319495473							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544649	COc1ccccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H17ClN4O3/c1-3-18(26)23-13-7-6-8-14(11-13)28-19-15(21)12-22-20(25-19)24-16-9-4-5-10-17(16)27-2/h3-12H,1H2,2H3,(H,23,26)(H,22,24,25)	DSRXZMGDJDQWJM-UHFFFAOYSA-N	202380	US9238629, I-12::US10081606, Compound I-12::US9765038, Compound I-12	Epidermal growth factor receptor	Human		 650					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333997	319495474							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544651	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19BrN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	OKWMEKZLQMLGEO-UHFFFAOYSA-N	202381	US9238629, I-13::US10081606, Compound I-13::US9765038, Compound I-13	Epidermal growth factor receptor	Human		 65.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333998	319495475							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544653	COc1cccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H20BrN5O3/c1-4-18(28)24-13-7-5-8-14(11-13)25-20-15(22)12-23-21(27-20)26-16-9-6-10-17(29-2)19(16)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	GZIGQTZRHLRBJL-UHFFFAOYSA-N	285865	US10081606, Compound I-14::US9765038, Compound I-14	Epidermal growth factor receptor	Human		 650					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=285865	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=285865&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333999	378169502							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544655	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19ClN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	UVQSPGYTMSYCFZ-UHFFFAOYSA-N	202383	US9238629, I-15::US10081606, Compound I-15::US9765038, Compound I-15	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334000	319495476							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544657	COc1cccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H20F3N5O3/c1-4-18(31)27-13-7-5-8-14(11-13)28-20-15(22(23,24)25)12-26-21(30-20)29-16-9-6-10-17(32-2)19(16)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	NBLFLERZTPRKQT-UHFFFAOYSA-N	202384	US9238629, I-16::US10081606, Compound I-16::US9765038, Compound I-16	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334304	319495477							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544659	COc1cccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H19ClN4O4/c1-4-18(27)24-13-7-5-8-14(11-13)30-20-15(22)12-23-21(26-20)25-16-9-6-10-17(28-2)19(16)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	JNDJZQKLKVLDLW-UHFFFAOYSA-N	285868	US10081606, Compound I-17::US9765038, Compound I-17	Epidermal growth factor receptor	Human		 650					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=285868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=285868&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334157	378169505							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544661	COc1ccccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H18ClN5O2/c1-3-18(27)23-13-7-6-8-14(11-13)24-19-15(21)12-22-20(26-19)25-16-9-4-5-10-17(16)28-2/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	IJBMVFJGJFRXOX-UHFFFAOYSA-N	202386	US9238629, I-18::US10081606, Compound I-18::US9765038, Compound I-18	Epidermal growth factor receptor	Human		 650					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334158	319495479							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544663	COc1ccccc1Nc1ncc(F)c(Oc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H17FN4O3/c1-3-18(26)23-13-7-6-8-14(11-13)28-19-15(21)12-22-20(25-19)24-16-9-4-5-10-17(16)27-2/h3-12H,1H2,2H3,(H,23,26)(H,22,24,25)	XSYRRKUEQTWUCQ-UHFFFAOYSA-N	202387	US9238629, I-19::US10081606, Compound I-19::US9765038, Compound I-19	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334159	319495480							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544665	COc1ccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H20BrN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-17-9-8-15(29-2)11-18(17)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	HPWXLWYAEGDGKI-UHFFFAOYSA-N	202388	US9238629, I-20::US10081606, Compound I-20::US9765038, Compound I-20	Epidermal growth factor receptor	Human		 65.0					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202388	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202388&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334160	319495481							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544667	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H20ClN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-17-9-8-15(29-2)11-18(17)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	UGZHYAQGGADKAK-UHFFFAOYSA-N	202389	US9238629, I-21::US10081606, Compound I-21::US9765038, Compound I-21	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334161	319495482							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544669	COc1ccccc1Nc1ncc(Br)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H18BrN5O2/c1-3-18(27)23-13-7-6-8-14(11-13)24-19-15(21)12-22-20(26-19)25-16-9-4-5-10-17(16)28-2/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	FMTXHOXUJYVAMG-UHFFFAOYSA-N	202390	US9238629, I-22::US10081606, Compound I-22::US9765038, Compound I-22	Epidermal growth factor receptor	Human		 200					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202390	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202390&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334303	319495483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
544671	COc1cccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H19F3N4O4/c1-4-18(30)27-13-7-5-8-14(11-13)33-20-15(22(23,24)25)12-26-21(29-20)28-16-9-6-10-17(31-2)19(16)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	HIMGGUFXIBERNV-UHFFFAOYSA-N	202391	US9238629, I-23::US10081606, Compound I-23::US9765038, Compound I-23	Epidermal growth factor receptor	Human		>1000					7.5000		US Patent		10.7270/Q2HH6N3X		aid1795705	US10081606	Lee, K; Niu, D; Petter, RC; Singh, J	9/25/2018	1/12/2019	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202391	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202391&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334156	319495484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548553	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cnn(C)c3)n2n1	InChI=1S/C25H31N9O2/c1-7-24(35)28-19-12-20(23(36-6)13-22(19)32(4)11-10-31(2)3)29-25-26-15-18-8-9-21(34(18)30-25)17-14-27-33(5)16-17/h7-9,12-16H,1,10-11H2,2-6H3,(H,28,35)(H,29,30)	FLWVRQWDQZPSPP-UHFFFAOYSA-N	287595	US10085983, Compound J-1::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(7-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 4.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287595	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287595&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311832	378171162							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548556	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cnn(C)c3)n2n1	InChI=1S/C27H33N9O2/c1-6-26(37)30-21-13-22(25(38-5)14-24(21)35-11-9-19(10-12-35)33(2)3)31-27-28-16-20-7-8-23(36(20)32-27)18-15-29-34(4)17-18/h6-8,13-17,19H,1,9-12H2,2-5H3,(H,30,37)(H,31,32)	TUZBYIGNLKAMOQ-UHFFFAOYSA-N	287607	US10085983, Compound J-2::N-(2-(4-(dimethylamino)piperidin-1-yl)-4-methoxy-5-(7-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-f][11,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 23.0						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287607	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287607&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311842	378171174							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548559	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cnn(C)c3)n2n1	InChI=1S/C24H28N8O3/c1-6-23(33)27-19-11-18(21(34-5)12-22(19)35-10-9-30(2)3)28-24-25-14-17-7-8-20(32(17)29-24)16-13-26-31(4)15-16/h6-8,11-15H,1,9-10H2,2-5H3,(H,27,33)(H,28,29)	OXYMNMOOOGHQAV-UHFFFAOYSA-N	287608	US10085983, Compound J-3::N-(2-(2-(dimethylamino)ethoxyl)-4-methoxy-5-(7-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 10.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287608&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311838	378171175							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548562	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cnn(C)c3)n2n1	InChI=1S/C25H29N9O2/c1-5-24(35)28-19-12-20(23(36-4)13-22(19)33-10-8-31(2)9-11-33)29-25-26-15-18-6-7-21(34(18)30-25)17-14-27-32(3)16-17/h5-7,12-16H,1,8-11H2,2-4H3,(H,28,35)(H,29,30)	NRCYEKWQFFQWOR-UHFFFAOYSA-N	287609	US10085983, Compound J-4:: N-(4-methoxy-5-(7-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)-2-(4-methyl-1-yl)phenyl)acrylamide	Epidermal growth factor receptor	Human		 35.0						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287609	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287609&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311821	378171176							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548565	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(C3=CCCCC3)n2n1 |t:29|	InChI=1S/C27H35N7O2/c1-6-26(35)29-21-16-22(25(36-5)17-24(21)33(4)15-14-32(2)3)30-27-28-18-20-12-13-23(34(20)31-27)19-10-8-7-9-11-19/h6,10,12-13,16-18H,1,7-9,11,14-15H2,2-5H3,(H,29,35)(H,30,31)	POZRCONTKQCSTI-UHFFFAOYSA-N	287610	US10085983, Compound J-5::N-(5(7-cyclohexenyl-pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide	Epidermal growth factor receptor	Human		 9.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287610	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287610&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311765	378171177							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548568	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cccnc3)n2n1	InChI=1S/C26H30N8O2/c1-6-25(35)29-20-14-21(24(36-5)15-23(20)33(4)13-12-32(2)3)30-26-28-17-19-9-10-22(34(19)31-26)18-8-7-11-27-16-18/h6-11,14-17H,1,12-13H2,2-5H3,(H,29,35)(H,30,31)	BQPJNBCABAQSBW-UHFFFAOYSA-N	287611	US10085983, Compound J-6::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(7-(pyridin-3-yl)pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 13.0						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287611	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287611&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311764	378171178							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548571	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cnc4n(C)ccc4c3)n2n1	InChI=1S/C29H33N9O2/c1-7-27(39)32-22-15-23(26(40-6)16-25(22)36(4)13-12-35(2)3)33-29-31-18-21-8-9-24(38(21)34-29)20-14-19-10-11-37(5)28(19)30-17-20/h7-11,14-18H,1,12-13H2,2-6H3,(H,32,39)(H,33,34)	WICFMJVCJSYGLX-UHFFFAOYSA-N	287612	US10085983, Compound J-7::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(7-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 5.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287612	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287612&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311767	378171179							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548574	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(C3CC3)n2n1	InChI=1S/C24H31N7O2/c1-6-23(32)26-18-13-19(22(33-5)14-21(18)30(4)12-11-29(2)3)27-24-25-15-17-9-10-20(16-7-8-16)31(17)28-24/h6,9-10,13-16H,1,7-8,11-12H2,2-5H3,(H,26,32)(H,27,28)	SQRJEKHKFMXRFH-UHFFFAOYSA-N	287613	US10085983, Compound J-8::N-(5(7-cyclopropylpyrrolo[1,2-f][1,2,4]triazin-2-ylamino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide	Epidermal growth factor receptor	Human		 112						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287613&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311766	378171180							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548577	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(C)n2n1	InChI=1S/C22H29N7O2/c1-7-21(30)24-17-12-18(20(31-6)13-19(17)28(5)11-10-27(3)4)25-22-23-14-16-9-8-15(2)29(16)26-22/h7-9,12-14H,1,10-11H2,2-6H3,(H,24,30)(H,25,26)	ZGIBAXLVHBLNHY-UHFFFAOYSA-N	287614	US10085983, Compound J-9::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(7-methylpyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 105						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287614	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287614&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311882	378171181							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548580	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cnc4ccccc4c3)n2n1	InChI=1S/C30H32N8O2/c1-6-29(39)33-24-16-25(28(40-5)17-27(24)37(4)14-13-36(2)3)34-30-32-19-22-11-12-26(38(22)35-30)21-15-20-9-7-8-10-23(20)31-18-21/h6-12,15-19H,1,13-14H2,2-5H3,(H,33,39)(H,34,35)	SWWCJVAACVQXKA-UHFFFAOYSA-N	287615	US10085983, Compound J-10::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(7-(quinolin-3-yl)pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 3.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287615	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287615&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311841	378171182							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548583	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3ccccc3)n2n1	InChI=1S/C27H31N7O2/c1-6-26(35)29-21-16-22(25(36-5)17-24(21)33(4)15-14-32(2)3)30-27-28-18-20-12-13-23(34(20)31-27)19-10-8-7-9-11-19/h6-13,16-18H,1,14-15H2,2-5H3,(H,29,35)(H,30,31)	WSAZSRLUAGXQFR-UHFFFAOYSA-N	287616	US10085983, Compound J-11::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(7-phenylpyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 10.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287616&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311887	378171183							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548586	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3ccn(C)c3)n2n1	InChI=1S/C26H32N8O2/c1-7-25(35)28-20-14-21(24(36-6)15-23(20)33(5)13-12-31(2)3)29-26-27-16-19-8-9-22(34(19)30-26)18-10-11-32(4)17-18/h7-11,14-17H,1,12-13H2,2-6H3,(H,28,35)(H,29,30)	VRTQWMWQYLZAOW-UHFFFAOYSA-N	287617	US10085983, Compound J-12	Epidermal growth factor receptor	Human		 8.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287617&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311848	378171184							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548589	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(-c3cnc4ccccc4c3)n2n1	InChI=1S/C32H34N8O2/c1-5-31(41)35-26-17-27(30(42-4)18-29(26)39-14-12-23(13-15-39)38(2)3)36-32-34-20-24-10-11-28(40(24)37-32)22-16-21-8-6-7-9-25(21)33-19-22/h5-11,16-20,23H,1,12-15H2,2-4H3,(H,35,41)(H,36,37)	YOUNCWKUFGWLLZ-UHFFFAOYSA-N	287618	US10085983, Compound J-13::N-(2-(4-(dimethylamino)piperidin-1-yl)-4-methoxy-5-(7-(quinolin-3-yl)pyrrolo[1,2-f][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 21.0						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287618&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311770	378171185							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548592	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(C)n2n1	InChI=1S/C24H31N7O2/c1-6-23(32)26-19-13-20(27-24-25-15-18-8-7-16(2)31(18)28-24)22(33-5)14-21(19)30-11-9-17(10-12-30)29(3)4/h6-8,13-15,17H,1,9-12H2,2-5H3,(H,26,32)(H,27,28)	UNAKDSAXWVXYRR-UHFFFAOYSA-N	287619	US10085983, Compound J-14::N-(2-(4-(dimethylamino)piperidin-1-yl)-4-methoxy-5-(7-methylpyrrolo[1,2-f][1,2,4]triazin-2-yl amino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 104						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287619	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287619&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311771	378171186							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548595	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc2ccc(C3CC3)n2n1	InChI=1S/C26H33N7O2/c1-5-25(34)28-20-14-21(24(35-4)15-23(20)32-12-10-18(11-13-32)31(2)3)29-26-27-16-19-8-9-22(17-6-7-17)33(19)30-26/h5,8-9,14-18H,1,6-7,10-13H2,2-4H3,(H,28,34)(H,29,30)	YGYOFKRCXLNMMX-UHFFFAOYSA-N	287620	US10085983, Compound J-15::N-(5(7-cyclopropylpyrrolo[1,2-f][1,2,4]triazin-2-ylamino)-2-(4-(dimethylamino)piperidin-1-yl)-4-methoxyphenyl)acrylamide	Epidermal growth factor receptor	Human		>1000						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287620&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311768	378171187							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548598	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc2c(C)cc(-c3cnn(C)c3)n2n1	InChI=1S/C26H33N9O2/c1-8-25(36)29-19-12-20(24(37-7)13-22(19)33(5)10-9-32(3)4)30-26-27-15-23-17(2)11-21(35(23)31-26)18-14-28-34(6)16-18/h8,11-16H,1,9-10H2,2-7H3,(H,29,36)(H,30,31)	SGFLIVBLWXEBRN-UHFFFAOYSA-N	287621	US10085983, Compound J-20::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(5-methyl-7-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-F][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		 294						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287621	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287621&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311769	378171188							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548601	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc2c(C)cc(-c3cnn(C)c3)n2n1	InChI=1S/C28H35N9O2/c1-7-27(38)31-21-13-22(26(39-6)14-24(21)36-10-8-20(9-11-36)34(3)4)32-28-29-16-25-18(2)12-23(37(25)33-28)19-15-30-35(5)17-19/h7,12-17,20H,1,8-11H2,2-6H3,(H,31,38)(H,32,33)	URSAXSRJAQPZNS-UHFFFAOYSA-N	287622	US10085983, Compound J-21::The Preparation of N-(2-(4-(dimethylamino)piperidin-1-yl)-4-methoxy-5-(5-methyl-7-(1-methyl-1H-pyrazol-4-yl) pyrrolo[1,2-F][1,2,4]triazin-2-ylamino)phenyl)acrylamide	Epidermal growth factor receptor	Human		>1000						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287622&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130311891	378171189							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548604	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12	InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)	DUYJMQONPNNFPI-UHFFFAOYSA-N	50029668	AZD-9291::Osimertinib::US10085983, Compound AZD-9291::US10227342, Example 24::US9890168, Compound AZD-9291::US11111233, Example AZD9291::WO2022090481, Example osimertinib::US20230322822, Compound AZD9291::US11896597, Compound AZD9291	Epidermal growth factor receptor	Human		 3.00						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029668&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496458	313065691	90949		DB09330				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
548607	CN(C)C/C=C/C(=O)Nc1cc2c(cc1O[C@H]3CCOC3)ncnc2Nc4ccc(c(c4)Cl)F	InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)	ULXXDDBFHOBEHA-UHFFFAOYSA-N	50322823	(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide::CHEMBL1173655::AFATINIB::US9388170, Afatinib::US10085983, Compound BIBW2992::US10196365, Afatinib::US9890168, Compound BIBW2992::US10435400, Compound BIBW2992::WO2022090481, Example afatinib::US11896597, Compound Afatinib::US20240358711, Compound Afatanib	Epidermal growth factor receptor	Human		 1.000						25.00 C	US Patent		10.7270/Q28W3GBG		aid1795741	US10085983	Jin, Y; Bu, P; He, Q; Lan, J; Zhou, F; Zhang, L; He, X	10/2/2018	1/17/2019	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322823&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0WM	4G5J	10184653	104144352	94698	CHEMBL1173655	DB08916				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555754	CC(=C)C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C22H21ClN8O3/c1-11(2)21(33)30-7-3-4-13(9-30)31-19-16(18(24)25-10-26-19)17(29-31)20(32)28-22-27-14-8-12(23)5-6-15(14)34-22/h5-6,8,10,13H,1,3-4,7,9H2,2H3,(H2,24,25,26)(H,27,28,32)	YSNNXWDSOJMVRP-UHFFFAOYSA-N	291273	US9580432, Example 4::5-cyanobenzo[d]oxazol-2-amine	Epidermal growth factor receptor	Human		 929					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291273	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291273&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519900	381611578							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555755	C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C22H21ClN8O3/c1-2-4-16(32)30-8-3-5-13(10-30)31-20-17(19(24)25-11-26-20)18(29-31)21(33)28-22-27-14-9-12(23)6-7-15(14)34-22/h2,4,6-7,9,11,13H,3,5,8,10H2,1H3,(H2,24,25,26)(H,27,28,33)	SCQLYOZUYSYZHC-UHFFFAOYSA-N	291274	US9580432, Example 5	Epidermal growth factor receptor	Human		 241					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291274	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291274&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519839	381611579							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555756	Nc1ncnc2n(nc(C(=O)Nc3nc4ccc(cc4o3)C#N)c12)[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C22H19N9O3/c1-2-16(32)30-7-3-4-13(10-30)31-20-17(19(24)25-11-26-20)18(29-31)21(33)28-22-27-14-6-5-12(9-23)8-15(14)34-22/h2,5-6,8,11,13H,1,3-4,7,10H2,(H2,24,25,26)(H,27,28,33)	WGOPGICDGMYHTI-UHFFFAOYSA-N	291275	US9580432, Example 6	Epidermal growth factor receptor	Human		 33.3					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291275	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291275&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121295776	381611580							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555757	COCCc1ccc2oc(NC(=O)c3nn([C@@H]4CCCN(C4)C(=O)C=C)c4ncnc(N)c34)nc2c1 |r|	InChI=1S/C24H26N8O4/c1-3-18(33)31-9-4-5-15(12-31)32-22-19(21(25)26-13-27-22)20(30-32)23(34)29-24-28-16-11-14(8-10-35-2)6-7-17(16)36-24/h3,6-7,11,13,15H,1,4-5,8-10,12H2,2H3,(H2,25,26,27)(H,28,29,34)	DBGUXAWCNQYKMH-UHFFFAOYSA-N	291277	US9580432, Example 8	Epidermal growth factor receptor	Human		 22.9					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291277	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291277&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519810	381611582							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555758	Nc1ncnc2n(nc(C(=O)Nc3nc4ncccc4o3)c12)[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C20H19N9O3/c1-2-13(30)28-8-4-5-11(9-28)29-18-14(16(21)23-10-24-18)15(27-29)19(31)26-20-25-17-12(32-20)6-3-7-22-17/h2-3,6-7,10-11H,1,4-5,8-9H2,(H2,21,23,24)(H,22,25,26,31)	PZSQYQQPTYOEBC-UHFFFAOYSA-N	291278	US9580432, Example 9	Epidermal growth factor receptor	Human		 28.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291278	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291278&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519780	381611583							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555759	CC(=C)C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(F)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C22H21FN8O3/c1-11(2)21(33)30-7-3-4-13(9-30)31-19-16(18(24)25-10-26-19)17(29-31)20(32)28-22-27-14-8-12(23)5-6-15(14)34-22/h5-6,8,10,13H,1,3-4,7,9H2,2H3,(H2,24,25,26)(H,27,28,32)	OJWPRERQKVQUMR-UHFFFAOYSA-N	291280	US9580432, Example 11	Epidermal growth factor receptor	Human		 1295					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291280	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291280&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519830	381611585							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555760	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(F)ccc4o3)c12)[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C21H19FN8O3/c1-2-15(31)29-7-3-4-12(9-29)30-19-16(18(23)24-10-25-19)17(28-30)20(32)27-21-26-13-8-11(22)5-6-14(13)33-21/h2,5-6,8,10,12H,1,3-4,7,9H2,(H2,23,24,25)(H,26,27,32)	XCTFFUYIMFTLML-UHFFFAOYSA-N	291281	US9580432, Example 12	Epidermal growth factor receptor	Human		 84.2					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291281	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291281&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90647177	381611586							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555761	Nc1ncnc2n(nc(C(=O)Nc3nc4ccccc4o3)c12)[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C21H20N8O3/c1-2-15(30)28-9-5-6-12(10-28)29-19-16(18(22)23-11-24-19)17(27-29)20(31)26-21-25-13-7-3-4-8-14(13)32-21/h2-4,7-8,11-12H,1,5-6,9-10H2,(H2,22,23,24)(H,25,26,31)	WUMMDJMYFAWMBN-UHFFFAOYSA-N	291282	US9580432, Example 13::US10280174, Compound A	Epidermal growth factor receptor	Human		 28.8					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291282	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291282&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519887	381611587							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555762	C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3ccccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C22H22N8O3/c1-2-6-16(31)29-10-5-7-13(11-29)30-20-17(19(23)24-12-25-20)18(28-30)21(32)27-22-26-14-8-3-4-9-15(14)33-22/h2-4,6,8-9,12-13H,5,7,10-11H2,1H3,(H2,23,24,25)(H,26,27,32)	DLGLFSDRZNEFAE-UHFFFAOYSA-N	291283	US9580432, Example 14	Epidermal growth factor receptor	Human		 128					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291283	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291283&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519764	381611588							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555763	CN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C24H26ClN9O3/c1-32(2)9-4-6-18(35)33-10-3-5-15(12-33)34-22-19(21(26)27-13-28-22)20(31-34)23(36)30-24-29-16-11-14(25)7-8-17(16)37-24/h4,6-8,11,13,15H,3,5,9-10,12H2,1-2H3,(H2,26,27,28)(H,29,30,36)	LSCBIFHNPDMWIW-UHFFFAOYSA-N	291284	US9580432, Example 15	Epidermal growth factor receptor	Human		 145					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291284	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291284&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519765	381611589							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555764	CCN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C25H28ClN9O3/c1-3-33(2)10-5-7-19(36)34-11-4-6-16(13-34)35-23-20(22(27)28-14-29-23)21(32-35)24(37)31-25-30-17-12-15(26)8-9-18(17)38-25/h5,7-9,12,14,16H,3-4,6,10-11,13H2,1-2H3,(H2,27,28,29)(H,30,31,37)	GUWCFQQMBRWJAT-UHFFFAOYSA-N	291285	US9580432, Example 16	Epidermal growth factor receptor	Human		 158					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291285	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291285&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293534	381611590							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555765	CCN(CC)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C26H30ClN9O3/c1-3-34(4-2)11-6-8-20(37)35-12-5-7-17(14-35)36-24-21(23(28)29-15-30-24)22(33-36)25(38)32-26-31-18-13-16(27)9-10-19(18)39-26/h6,8-10,13,15,17H,3-5,7,11-12,14H2,1-2H3,(H2,28,29,30)(H,31,32,38)	JTMWQUYZSGIWPE-UHFFFAOYSA-N	291286	US9580432, Example 17	Epidermal growth factor receptor	Human		 157					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291286	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291286&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293523	381611591							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555766	CC(C)N(C)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C26H30ClN9O3/c1-15(2)34(3)10-5-7-20(37)35-11-4-6-17(13-35)36-24-21(23(28)29-14-30-24)22(33-36)25(38)32-26-31-18-12-16(27)8-9-19(18)39-26/h5,7-9,12,14-15,17H,4,6,10-11,13H2,1-3H3,(H2,28,29,30)(H,31,32,38)	ONUKEVKZBUDRTK-UHFFFAOYSA-N	291287	US9580432, Example 18	Epidermal growth factor receptor	Human		 121					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291287	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291287&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293532	381611592							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555767	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CCCN(C1)C(=O)\C=C\CN1CCCC1 |r|	InChI=1S/C26H28ClN9O3/c27-16-7-8-19-18(13-16)31-26(39-19)32-25(38)22-21-23(28)29-15-30-24(21)36(33-22)17-5-3-12-35(14-17)20(37)6-4-11-34-9-1-2-10-34/h4,6-8,13,15,17H,1-3,5,9-12,14H2,(H2,28,29,30)(H,31,32,38)	NJQKXLPNGPRPBX-UHFFFAOYSA-N	291288	US9580432, Example 19	Epidermal growth factor receptor	Human		 145					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291288	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291288&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519779	381611593							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555768	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CCCN(C1)C(=O)\C=C\CN1CCCCC1 |r|	InChI=1S/C27H30ClN9O3/c28-17-8-9-20-19(14-17)32-27(40-20)33-26(39)23-22-24(29)30-16-31-25(22)37(34-23)18-6-4-13-36(15-18)21(38)7-5-12-35-10-2-1-3-11-35/h5,7-9,14,16,18H,1-4,6,10-13,15H2,(H2,29,30,31)(H,32,33,39)	AKSBYWGFGIJRFN-UHFFFAOYSA-N	291289	US9580432, Example 20	Epidermal growth factor receptor	Human		 138					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291289	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291289&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519878	381611594							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555769	CN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(ccc3o2)-c2cccs2)c2c(N)ncnc12 |r|	InChI=1S/C28H29N9O3S/c1-35(2)11-4-8-22(38)36-12-3-6-18(15-36)37-26-23(25(29)30-16-31-26)24(34-37)27(39)33-28-32-19-14-17(9-10-20(19)40-28)21-7-5-13-41-21/h4-5,7-10,13-14,16,18H,3,6,11-12,15H2,1-2H3,(H2,29,30,31)(H,32,33,39)	CLBMDOIIODQDOI-UHFFFAOYSA-N	291290	US9580432, Example 21	Epidermal growth factor receptor	Human		 147					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291290	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291290&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519838	381611595							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555770	CC#CC(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3ccccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C22H20N8O3/c1-2-6-16(31)29-10-5-7-13(11-29)30-20-17(19(23)24-12-25-20)18(28-30)21(32)27-22-26-14-8-3-4-9-15(14)33-22/h3-4,8-9,12-13H,5,7,10-11H2,1H3,(H2,23,24,25)(H,26,27,32)	UFSANITUDDIZER-UHFFFAOYSA-N	291291	US9580432, Example 22	Epidermal growth factor receptor	Human		 260					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291291	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291291&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293538	381611596							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555771	C\C=C\C(=O)N1CC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C21H19ClN8O3/c1-2-3-15(31)29-7-6-12(9-29)30-19-16(18(23)24-10-25-19)17(28-30)20(32)27-21-26-13-8-11(22)4-5-14(13)33-21/h2-5,8,10,12H,6-7,9H2,1H3,(H2,23,24,25)(H,26,27,32)	DDWOKHFHOQZXSM-UHFFFAOYSA-N	291294	US9580432, Example 25	Epidermal growth factor receptor	Human		 174					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519777	381611599							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555772	[#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-1-[#6]-[#6]-[#6@H](-[#6]-1)-n1nc(-[#6](=O)-[#7]-c2nc3cc(Cl)ccc3o2)c2c(-[#7])ncnc12 |r|	InChI=1S/C22H5ClN8O3/c1-11(2)7-16(32)30-6-5-13(9-30)31-20-17(19(24)25-10-26-20)18(29-31)21(33)28-22-27-14-8-12(23)3-4-15(14)34-22/h3-4,8,10,13H	WZGFWVQPJATJKH-UHFFFAOYSA-N	291295	US9580432, Example 26	Epidermal growth factor receptor	Human		 643					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291295	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291295&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519744	381611600							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555773	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(F)ccc4o3)c12)[C@@H]1CCN(C1)C(=O)C=C |r|	InChI=1S/C20H17FN8O3/c1-2-14(30)28-6-5-11(8-28)29-18-15(17(22)23-9-24-18)16(27-29)19(31)26-20-25-12-7-10(21)3-4-13(12)32-20/h2-4,7,9,11H,1,5-6,8H2,(H2,22,23,24)(H,25,26,31)	MBTQEKOQTVSXTJ-UHFFFAOYSA-N	291299	US9580432, Example 30	Epidermal growth factor receptor	Human		 21.3					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291299	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291299&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519833	381611604							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555774	CN(C)C\C=C\C(=O)N1CC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C23H24ClN9O3/c1-31(2)8-3-4-17(34)32-9-7-14(11-32)33-21-18(20(25)26-12-27-21)19(30-33)22(35)29-23-28-15-10-13(24)5-6-16(15)36-23/h3-6,10,12,14H,7-9,11H2,1-2H3,(H2,25,26,27)(H,28,29,35)	VAHPHFUKSVSWLN-UHFFFAOYSA-N	291301	US9580432, Example 32	Epidermal growth factor receptor	Human		 43.1					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291301	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291301&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519758	381611606							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555775	CCN(C)C\C=C\C(=O)N1CC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C24H26ClN9O3/c1-3-32(2)9-4-5-18(35)33-10-8-15(12-33)34-22-19(21(26)27-13-28-22)20(31-34)23(36)30-24-29-16-11-14(25)6-7-17(16)37-24/h4-7,11,13,15H,3,8-10,12H2,1-2H3,(H2,26,27,28)(H,29,30,36)	RMEXMUZSBBDEDL-UHFFFAOYSA-N	291302	US9580432, Example 33	Epidermal growth factor receptor	Human		 43.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291302	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291302&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293526	381611607							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555776	CCN(CC)C\C=C\C(=O)N1CC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C25H28ClN9O3/c1-3-33(4-2)10-5-6-19(36)34-11-9-16(13-34)35-23-20(22(27)28-14-29-23)21(32-35)24(37)31-25-30-17-12-15(26)7-8-18(17)38-25/h5-8,12,14,16H,3-4,9-11,13H2,1-2H3,(H2,27,28,29)(H,30,31,37)	RJVIZUPPBGFXBG-UHFFFAOYSA-N	291303	US9580432, Example 34	Epidermal growth factor receptor	Human		 79.3					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291303	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291303&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293536	381611608							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555777	CC(C)N(C)C\C=C\C(=O)N1CC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C25H28ClN9O3/c1-14(2)33(3)9-4-5-19(36)34-10-8-16(12-34)35-23-20(22(27)28-13-29-23)21(32-35)24(37)31-25-30-17-11-15(26)6-7-18(17)38-25/h4-7,11,13-14,16H,8-10,12H2,1-3H3,(H2,27,28,29)(H,30,31,37)	BNUOFOQJYOAURP-UHFFFAOYSA-N	291304	US9580432, Example 35	Epidermal growth factor receptor	Human		 35.1					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291304	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291304&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293518	381611609							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555778	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CCN(C1)C(=O)\C=C\CN1CCCC1 |r|	InChI=1S/C25H26ClN9O3/c26-15-5-6-18-17(12-15)30-25(38-18)31-24(37)21-20-22(27)28-14-29-23(20)35(32-21)16-7-11-34(13-16)19(36)4-3-10-33-8-1-2-9-33/h3-6,12,14,16H,1-2,7-11,13H2,(H2,27,28,29)(H,30,31,37)	DEDVTJJLTCNPHD-UHFFFAOYSA-N	291305	US9580432, Example 36	Epidermal growth factor receptor	Human		 59.8					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291305	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291305&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519895	381611610							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555779	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CCN(C1)C(=O)\C=C\CN1CCCCC1 |r|	InChI=1S/C26H28ClN9O3/c27-16-6-7-19-18(13-16)31-26(39-19)32-25(38)22-21-23(28)29-15-30-24(21)36(33-22)17-8-12-35(14-17)20(37)5-4-11-34-9-2-1-3-10-34/h4-7,13,15,17H,1-3,8-12,14H2,(H2,28,29,30)(H,31,32,38)	SZYMZZMXAVELOS-UHFFFAOYSA-N	291306	US9580432, Example 37	Epidermal growth factor receptor	Human		 70.5					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291306	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291306&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519770	381611611							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555780	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(ccc4o3)C#N)c12)[C@@H]1CCN(C1)C(=O)C=C |r|	InChI=1S/C21H17N9O3/c1-2-15(31)29-6-5-12(9-29)30-19-16(18(23)24-10-25-19)17(28-30)20(32)27-21-26-13-7-11(8-22)3-4-14(13)33-21/h2-4,7,10,12H,1,5-6,9H2,(H2,23,24,25)(H,26,27,32)	JMYYVBHVFUGNNN-UHFFFAOYSA-N	291308	US9580432, Example 39	Epidermal growth factor receptor	Human		 37.5					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291308	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291308&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519844	381611613							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555781	COCCc1ccc2oc(NC(=O)c3nn([C@@H]4CCN(C4)C(=O)C=C)c4ncnc(N)c34)nc2c1 |r|	InChI=1S/C23H24N8O4/c1-3-17(32)30-8-6-14(11-30)31-21-18(20(24)25-12-26-21)19(29-31)22(33)28-23-27-15-10-13(7-9-34-2)4-5-16(15)35-23/h3-5,10,12,14H,1,6-9,11H2,2H3,(H2,24,25,26)(H,27,28,33)	PHKGTKKOFIGCOP-UHFFFAOYSA-N	291309	US9580432, Example 40	Epidermal growth factor receptor	Human		 10.00					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519846	381611614							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555782	CN(C)C\C=C\C(=O)N1CC[C@H](C1)n1nc(C(=O)Nc2nc3cc(ccc3o2)-c2ccccc2)c2c(N)ncnc12 |r|	InChI=1S/C29H29N9O3/c1-36(2)13-6-9-23(39)37-14-12-20(16-37)38-27-24(26(30)31-17-32-27)25(35-38)28(40)34-29-33-21-15-19(10-11-22(21)41-29)18-7-4-3-5-8-18/h3-11,15,17,20H,12-14,16H2,1-2H3,(H2,30,31,32)(H,33,34,40)	WJIJTAXDEGINAG-UHFFFAOYSA-N	291311	US9580432, Example 42	Epidermal growth factor receptor	Human		 19.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291311	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291311&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519834	381611616							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555783	CN(C)C\C=C\C(=O)N1CC[C@H](C1)n1nc(C(=O)Nc2nc3cc(ccc3o2)C(F)(F)F)c2c(N)ncnc12 |r|	InChI=1S/C24H24F3N9O3/c1-34(2)8-3-4-17(37)35-9-7-14(11-35)36-21-18(20(28)29-12-30-21)19(33-36)22(38)32-23-31-15-10-13(24(25,26)27)5-6-16(15)39-23/h3-6,10,12,14H,7-9,11H2,1-2H3,(H2,28,29,30)(H,31,32,38)	SYACMYUIHQGCPO-UHFFFAOYSA-N	291313	US9580432, Example 44	Epidermal growth factor receptor	Human		 17.1					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291313	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291313&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519882	381611618							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555784	CN(C)C\C=C\C(=O)N1CC(C1)N1CC(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c1ncnc2N	InChI=1S/C23H25ClN8O3/c1-30(2)7-3-4-18(33)31-9-14(10-31)32-11-15(19-20(25)26-12-27-21(19)32)22(34)29-23-28-16-8-13(24)5-6-17(16)35-23/h3-6,8,12,14-15H,7,9-11H2,1-2H3,(H2,25,26,27)(H,28,29,34)	OATSLRIJQCVEAS-UHFFFAOYSA-N	291316	US9580432, Example 47	Epidermal growth factor receptor	Human		 20.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291316	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291316&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121296141	381611621							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555785	CN(C)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C24H25ClN8O3/c1-31(2)8-3-4-19(34)32-9-7-15(11-32)33-12-16(20-21(26)27-13-28-22(20)33)23(35)30-24-29-17-10-14(25)5-6-18(17)36-24/h3-6,10,12-13,15H,7-9,11H2,1-2H3,(H2,26,27,28)(H,29,30,35)	ZWNMXIMNCMHVRJ-UHFFFAOYSA-N	291318	US9580432, Example 49	Epidermal growth factor receptor	Human		 24.8					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291318	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291318&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293544	381611622							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555786	CCN(C)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C25H27ClN8O3/c1-3-32(2)9-4-5-20(35)33-10-8-16(12-33)34-13-17(21-22(27)28-14-29-23(21)34)24(36)31-25-30-18-11-15(26)6-7-19(18)37-25/h4-7,11,13-14,16H,3,8-10,12H2,1-2H3,(H2,27,28,29)(H,30,31,36)	CCVMEUKMVMEKMR-UHFFFAOYSA-N	291319	US9580432, Example 50	Epidermal growth factor receptor	Human		 22.1					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291319	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291319&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293539	381611623							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555787	CCN(CC)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C26H29ClN8O3/c1-3-33(4-2)10-5-6-21(36)34-11-9-17(13-34)35-14-18(22-23(28)29-15-30-24(22)35)25(37)32-26-31-19-12-16(27)7-8-20(19)38-26/h5-8,12,14-15,17H,3-4,9-11,13H2,1-2H3,(H2,28,29,30)(H,31,32,37)	ZSQXDUJXJCOVQV-UHFFFAOYSA-N	291320	US9580432, Example 51	Epidermal growth factor receptor	Human		 31.1					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291320	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291320&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293522	381611624							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555788	CC(C)N(C)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C26H29ClN8O3/c1-15(2)33(3)9-4-5-21(36)34-10-8-17(12-34)35-13-18(22-23(28)29-14-30-24(22)35)25(37)32-26-31-19-11-16(27)6-7-20(19)38-26/h4-7,11,13-15,17H,8-10,12H2,1-3H3,(H2,28,29,30)(H,31,32,37)	BJUIFDSSUFWQEU-UHFFFAOYSA-N	291321	US9580432, Example 52	Epidermal growth factor receptor	Human		 20.6					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291321	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291321&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293527	381611625							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555789	Nc1ncnc2n(cc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CCN(C1)C(=O)\C=C\CN1CCCC1 |r|	InChI=1S/C26H27ClN8O3/c27-16-5-6-20-19(12-16)31-26(38-20)32-25(37)18-14-35(24-22(18)23(28)29-15-30-24)17-7-11-34(13-17)21(36)4-3-10-33-8-1-2-9-33/h3-6,12,14-15,17H,1-2,7-11,13H2,(H2,28,29,30)(H,31,32,37)	YUNZQWUKMZPWJU-UHFFFAOYSA-N	291322	US9580432, Example 53	Epidermal growth factor receptor	Human		 25.5					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291322	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291322&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293530	381611626							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555790	Nc1ncnc2n(cc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CCN(C1)C(=O)\C=C\CN1CCCCC1 |r|	InChI=1S/C27H29ClN8O3/c28-17-6-7-21-20(13-17)32-27(39-21)33-26(38)19-15-36(25-23(19)24(29)30-16-31-25)18-8-12-35(14-18)22(37)5-4-11-34-9-2-1-3-10-34/h4-7,13,15-16,18H,1-3,8-12,14H2,(H2,29,30,31)(H,32,33,38)	WGEKMVIECKZQRS-UHFFFAOYSA-N	291323	US9580432, Example 54	Epidermal growth factor receptor	Human		 37.1					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291323	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291323&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293515	381611627							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555791	CN(C)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(ccc3o2)-c2ccccc2)c2c(N)ncnc12 |r|	InChI=1S/C30H30N8O3/c1-36(2)13-6-9-25(39)37-14-12-21(16-37)38-17-22(26-27(31)32-18-33-28(26)38)29(40)35-30-34-23-15-20(10-11-24(23)41-30)19-7-4-3-5-8-19/h3-11,15,17-18,21H,12-14,16H2,1-2H3,(H2,31,32,33)(H,34,35,40)	SAAYJHNZQRUYEH-UHFFFAOYSA-N	291325	US9580432, Example 56	Epidermal growth factor receptor	Human		 17.6					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291325	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291325&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293545	381611629							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555792	CCN(C)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(ccc3o2)-c2ccccc2)c2c(N)ncnc12 |r|	InChI=1S/C31H32N8O3/c1-3-37(2)14-7-10-26(40)38-15-13-22(17-38)39-18-23(27-28(32)33-19-34-29(27)39)30(41)36-31-35-24-16-21(11-12-25(24)42-31)20-8-5-4-6-9-20/h4-12,16,18-19,22H,3,13-15,17H2,1-2H3,(H2,32,33,34)(H,35,36,41)	NTISBMCNVWOXOY-UHFFFAOYSA-N	291326	US9580432, Example 57	Epidermal growth factor receptor	Human		 19.3					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291326	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291326&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293531	381611630							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555793	CCN(CC)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(ccc3o2)-c2ccccc2)c2c(N)ncnc12 |r|	InChI=1S/C32H34N8O3/c1-3-38(4-2)15-8-11-27(41)39-16-14-23(18-39)40-19-24(28-29(33)34-20-35-30(28)40)31(42)37-32-36-25-17-22(12-13-26(25)43-32)21-9-6-5-7-10-21/h5-13,17,19-20,23H,3-4,14-16,18H2,1-2H3,(H2,33,34,35)(H,36,37,42)	XOMPMLIHBWZPPT-UHFFFAOYSA-N	291327	US9580432, Example 58	Epidermal growth factor receptor	Human		 23.5					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291327	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291327&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293524	381611631							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555794	CC(C)N(C)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(ccc3o2)-c2ccccc2)c2c(N)ncnc12 |r|	InChI=1S/C32H34N8O3/c1-20(2)38(3)14-7-10-27(41)39-15-13-23(17-39)40-18-24(28-29(33)34-19-35-30(28)40)31(42)37-32-36-25-16-22(11-12-26(25)43-32)21-8-5-4-6-9-21/h4-12,16,18-20,23H,13-15,17H2,1-3H3,(H2,33,34,35)(H,36,37,42)	FWCMAZYUSLLCTJ-UHFFFAOYSA-N	291328	US9580432, Example 59	Epidermal growth factor receptor	Human		 16.3					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291328	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291328&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293517	381611632							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555795	Nc1ncnc2n(cc(C(=O)Nc3nc4cc(ccc4o3)-c3ccccc3)c12)[C@@H]1CCN(C1)C(=O)\C=C\CN1CCCC1 |r|	InChI=1S/C32H32N8O3/c33-29-28-24(31(42)37-32-36-25-17-22(10-11-26(25)43-32)21-7-2-1-3-8-21)19-40(30(28)35-20-34-29)23-12-16-39(18-23)27(41)9-6-15-38-13-4-5-14-38/h1-3,6-11,17,19-20,23H,4-5,12-16,18H2,(H2,33,34,35)(H,36,37,42)	WAOGJGDMQVRBIS-UHFFFAOYSA-N	291329	US9580432, Example 60	Epidermal growth factor receptor	Human		 32.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291329	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291329&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293516	381611633							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555796	Nc1ncnc2n(cc(C(=O)Nc3nc4cc(ccc4o3)-c3ccccc3)c12)[C@@H]1CCN(C1)C(=O)\C=C\CN1CCCCC1 |r|	InChI=1S/C33H34N8O3/c34-30-29-25(32(43)38-33-37-26-18-23(11-12-27(26)44-33)22-8-3-1-4-9-22)20-41(31(29)36-21-35-30)24-13-17-40(19-24)28(42)10-7-16-39-14-5-2-6-15-39/h1,3-4,7-12,18,20-21,24H,2,5-6,13-17,19H2,(H2,34,35,36)(H,37,38,43)	MGERWQZUPXCLMR-UHFFFAOYSA-N	291330	US9580432, Example 61	Epidermal growth factor receptor	Human		 67.5					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291330	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291330&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121293543	381611634							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555797	Nc1ncnc2n(CC3CCCN(C3)C(=O)C=C)nc(C(=O)Nc3nc4ccccc4o3)c12	InChI=1S/C22H22N8O3/c1-2-16(31)29-9-5-6-13(10-29)11-30-20-17(19(23)24-12-25-20)18(28-30)21(32)27-22-26-14-7-3-4-8-15(14)33-22/h2-4,7-8,12-13H,1,5-6,9-11H2,(H2,23,24,25)(H,26,27,32)	JOLWLHDMAIYLGC-UHFFFAOYSA-N	291336	US9580432, Example 67	Epidermal growth factor receptor	Human		 18.0					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291336	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519788	381611640							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555798	Nc1ncnc2n(CC3CCN(CC3)C(=O)C=C)nc(C(=O)Nc3nc4ccccc4o3)c12	InChI=1S/C22H22N8O3/c1-2-16(31)29-9-7-13(8-10-29)11-30-20-17(19(23)24-12-25-20)18(28-30)21(32)27-22-26-14-5-3-4-6-15(14)33-22/h2-6,12-13H,1,7-11H2,(H2,23,24,25)(H,26,27,32)	TYRODWLXPZYVKN-UHFFFAOYSA-N	291337	US9580432, Example 68	Epidermal growth factor receptor	Human		 11.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291337	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291337&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519715	381611641							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555799	Nc1ncnc2n(CC3CN(C3)C(=O)C=C)nc(C(=O)Nc3nc4ccccc4o3)c12	InChI=1S/C20H18N8O3/c1-2-14(29)27-7-11(8-27)9-28-18-15(17(21)22-10-23-18)16(26-28)19(30)25-20-24-12-5-3-4-6-13(12)31-20/h2-6,10-11H,1,7-9H2,(H2,21,22,23)(H,24,25,30)	JQQNLSUBSWECQL-UHFFFAOYSA-N	291339	US9580432, Example 70	Epidermal growth factor receptor	Human		 12.2					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291339	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291339&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519685	381611643							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555800	Nc1ncnc2n(nc(C(=O)Nc3nc4ccccc4o3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C |r,wD:22.25,25.32,(-3.56,-2.8,;-3.56,-1.26,;-4.9,-.49,;-4.9,1.05,;-3.56,1.82,;-2.23,1.05,;-.76,1.53,;.14,.28,;-.76,-.96,;-.36,-2.45,;-1.45,-3.54,;1.12,-2.85,;1.52,-4.34,;2.99,-4.81,;2.99,-6.35,;4.13,-7.38,;3.81,-8.89,;2.35,-9.37,;1.2,-8.33,;1.52,-6.83,;.62,-5.58,;-2.23,-.49,;-.36,3.02,;-1.45,4.11,;-1.06,5.59,;.43,5.99,;1.52,4.9,;1.12,3.42,;.83,7.48,;2.32,7.88,;2.72,9.37,;3.41,6.79,;4.9,7.19,)|	InChI=1S/C22H22N8O3/c1-2-16(31)26-12-7-9-13(10-8-12)30-20-17(19(23)24-11-25-20)18(29-30)21(32)28-22-27-14-5-3-4-6-15(14)33-22/h2-6,11-13H,1,7-10H2,(H,26,31)(H2,23,24,25)(H,27,28,32)	FUPLQSLMGWHNRN-UHFFFAOYSA-N	291340	US9580432, Example 71	Epidermal growth factor receptor	Human		 42.0					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291340	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519772	381611644							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555801	Nc1ncnc2n(nc(C(=O)Nc3nc4ccccc4o3)c12)[C@H]1CC[C@@H](CC1)NC(=O)C=C |r,wU:25.32,wD:22.25,(-3.56,-2.8,;-3.56,-1.26,;-4.9,-.49,;-4.9,1.05,;-3.56,1.82,;-2.23,1.05,;-.76,1.53,;.14,.28,;-.76,-.96,;-.36,-2.45,;-1.45,-3.54,;1.12,-2.85,;1.52,-4.34,;2.99,-4.81,;2.99,-6.35,;4.13,-7.38,;3.81,-8.89,;2.35,-9.37,;1.2,-8.33,;1.52,-6.83,;.62,-5.58,;-2.23,-.49,;-.36,3.02,;1.12,3.42,;1.52,4.9,;.43,5.99,;-1.06,5.59,;-1.45,4.11,;.83,7.48,;2.32,7.88,;2.72,9.37,;3.41,6.79,;4.9,7.19,)|	InChI=1S/C22H22N8O3/c1-2-16(31)26-12-7-9-13(10-8-12)30-20-17(19(23)24-11-25-20)18(29-30)21(32)28-22-27-14-5-3-4-6-15(14)33-22/h2-6,11-13H,1,7-10H2,(H,26,31)(H2,23,24,25)(H,27,28,32)	FUPLQSLMGWHNRN-UHFFFAOYSA-N	291341	US9580432, Example 72	Epidermal growth factor receptor	Human		 12.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291341	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291341&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519772	381611645							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555802	CN(C)C\C=C\C(=O)N1CC[C@@H](C1)n1nc(C(=O)Nc2nc3ccccc3o2)c2c(N)ncnc12 |r|	InChI=1S/C23H25N9O3/c1-30(2)10-5-8-17(33)31-11-9-14(12-31)32-21-18(20(24)25-13-26-21)19(29-32)22(34)28-23-27-15-6-3-4-7-16(15)35-23/h3-8,13-14H,9-12H2,1-2H3,(H2,24,25,26)(H,27,28,34)	CWFRQOLJELCKGY-UHFFFAOYSA-N	291342	US9580432, Example 73	Epidermal growth factor receptor	Human		 11.2					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291342	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291342&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519683	381611646							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555803	Nc1ncnc2n(CC3CN(C3)C(=O)C=C)nc(C(=O)Nc3nc4cc(F)ccc4o3)c12	InChI=1S/C20H17FN8O3/c1-2-14(30)28-6-10(7-28)8-29-18-15(17(22)23-9-24-18)16(27-29)19(31)26-20-25-12-5-11(21)3-4-13(12)32-20/h2-5,9-10H,1,6-8H2,(H2,22,23,24)(H,25,26,31)	PFGUHPUJLMNDMO-UHFFFAOYSA-N	291344	US9580432, Example 75	Epidermal growth factor receptor	Human		 58.2					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291344&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519687	381611648							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555804	Nc1ncnc2n(CC3CN(C3)C(=O)C=C)nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12	InChI=1S/C20H17ClN8O3/c1-2-14(30)28-6-10(7-28)8-29-18-15(17(22)23-9-24-18)16(27-29)19(31)26-20-25-12-5-11(21)3-4-13(12)32-20/h2-5,9-10H,1,6-8H2,(H2,22,23,24)(H,25,26,31)	BBUDVNYJKYGCFW-UHFFFAOYSA-N	291345	US9580432, Example 76	Epidermal growth factor receptor	Human		 11.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291345&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519741	381611649							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555805	Nc1ncnc2n(CC3CCN(CC3)C(=O)C=C)nc(C(=O)Nc3nc4cc(F)ccc4o3)c12	InChI=1S/C22H21FN8O3/c1-2-16(32)30-7-5-12(6-8-30)10-31-20-17(19(24)25-11-26-20)18(29-31)21(33)28-22-27-14-9-13(23)3-4-15(14)34-22/h2-4,9,11-12H,1,5-8,10H2,(H2,24,25,26)(H,27,28,33)	GWSCKTFTVOIUTB-UHFFFAOYSA-N	291346	US9580432, Example 77	Epidermal growth factor receptor	Human		 204					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291346	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291346&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519768	381611650							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555806	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C |r,wU:23.26,26.33,(-3.59,-2.52,;-3.59,-.98,;-4.93,-.21,;-4.93,1.33,;-3.59,2.1,;-2.26,1.33,;-.79,1.81,;.11,.56,;-.79,-.69,;-.39,-2.17,;-1.48,-3.26,;1.09,-2.57,;1.49,-4.06,;2.96,-4.54,;2.96,-6.08,;4.1,-7.11,;3.78,-8.61,;4.93,-9.64,;2.32,-9.09,;1.17,-8.06,;1.49,-6.55,;.59,-5.31,;-2.26,-.21,;-.39,3.29,;1.09,3.69,;1.49,5.18,;.4,6.27,;-1.08,5.87,;-1.48,4.38,;.8,7.76,;2.29,8.15,;2.69,9.64,;3.38,7.07,;4.87,7.46,)|	InChI=1S/C22H21ClN8O3/c1-2-16(32)27-12-4-6-13(7-5-12)31-20-17(19(24)25-10-26-20)18(30-31)21(33)29-22-28-14-9-11(23)3-8-15(14)34-22/h2-3,8-10,12-13H,1,4-7H2,(H,27,32)(H2,24,25,26)(H,28,29,33)	DAPBDFRIJDKKFV-UHFFFAOYSA-N	291347	US9580432, Example 78	Epidermal growth factor receptor	Human		 101					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291347&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519852	381611651							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555807	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(F)ccc4o3)c12)C1CN(C1)C(=O)C=C	InChI=1S/C19H15FN8O3/c1-2-13(29)27-6-10(7-27)28-17-14(16(21)22-8-23-17)15(26-28)18(30)25-19-24-11-5-9(20)3-4-12(11)31-19/h2-5,8,10H,1,6-7H2,(H2,21,22,23)(H,24,25,30)	AKARSCXFYHOZHR-UHFFFAOYSA-N	291348	US9580432, Example 79	Epidermal growth factor receptor	Human		 20.6					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291348&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519797	381611652							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555808	Nc1ncnc2n(CC3CCN(CC3)C(=O)C=C)nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12	InChI=1S/C22H21ClN8O3/c1-2-16(32)30-7-5-12(6-8-30)10-31-20-17(19(24)25-11-26-20)18(29-31)21(33)28-22-27-14-9-13(23)3-4-15(14)34-22/h2-4,9,11-12H,1,5-8,10H2,(H2,24,25,26)(H,27,28,33)	BAZLMPWIGYDUQP-UHFFFAOYSA-N	291349	US9580432, Example 80	Epidermal growth factor receptor	Human		 75.4					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291349&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519736	381611653							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555809	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(F)ccc4o3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C |r,wU:23.26,26.33,(-3.59,-2.52,;-3.59,-.98,;-4.93,-.21,;-4.93,1.33,;-3.59,2.1,;-2.26,1.33,;-.79,1.81,;.11,.56,;-.79,-.69,;-.39,-2.17,;-1.48,-3.26,;1.09,-2.57,;1.49,-4.06,;2.96,-4.54,;2.96,-6.08,;4.1,-7.11,;3.78,-8.61,;4.93,-9.64,;2.32,-9.09,;1.17,-8.06,;1.49,-6.55,;.59,-5.31,;-2.26,-.21,;-.39,3.29,;1.09,3.69,;1.49,5.18,;.4,6.27,;-1.08,5.87,;-1.48,4.38,;.8,7.76,;2.29,8.15,;2.69,9.64,;3.38,7.07,;4.87,7.46,)|	InChI=1S/C22H21FN8O3/c1-2-16(32)27-12-4-6-13(7-5-12)31-20-17(19(24)25-10-26-20)18(30-31)21(33)29-22-28-14-9-11(23)3-8-15(14)34-22/h2-3,8-10,12-13H,1,4-7H2,(H,27,32)(H2,24,25,26)(H,28,29,33)	WPCYUFLUANHPEH-UHFFFAOYSA-N	291350	US9580432, Example 81	Epidermal growth factor receptor	Human		 205					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291350&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519822	381611654							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555810	Nc1ncnc2n(nc(C(=O)Nc3nc4ccccc4o3)c12)C1CCN(C1)C(=O)C=C	InChI=1S/C20H18N8O3/c1-2-14(29)27-8-7-11(9-27)28-18-15(17(21)22-10-23-18)16(26-28)19(30)25-20-24-12-5-3-4-6-13(12)31-20/h2-6,10-11H,1,7-9H2,(H2,21,22,23)(H,24,25,30)	LWIXMILEZATMDL-UHFFFAOYSA-N	291351	US9580432, Example 82	Epidermal growth factor receptor	Human		 10.9					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291351	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291351&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519748	381611655							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555811	Nc1ncnc2n(nc(C(=O)Nc3nc4cc(F)ccc4o3)c12)C1CCN(C1)C(=O)C=C	InChI=1S/C20H17FN8O3/c1-2-14(30)28-6-5-11(8-28)29-18-15(17(22)23-9-24-18)16(27-29)19(31)26-20-25-12-7-10(21)3-4-13(12)32-20/h2-4,7,9,11H,1,5-6,8H2,(H2,22,23,24)(H,25,26,31)	MBTQEKOQTVSXTJ-UHFFFAOYSA-N	291352	US9580432, Example 83	Epidermal growth factor receptor	Human		 39.6					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291352	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291352&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519837	381611656							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555812	Nc1ncnc2n(CCCNC(=O)C=C)nc(C(=O)Nc3nc4ccccc4o3)c12	InChI=1S/C19H18N8O3/c1-2-13(28)21-8-5-9-27-17-14(16(20)22-10-23-17)15(26-27)18(29)25-19-24-11-6-3-4-7-12(11)30-19/h2-4,6-7,10H,1,5,8-9H2,(H,21,28)(H2,20,22,23)(H,24,25,29)	ICBNFZRGYFGZLT-UHFFFAOYSA-N	291353	US9580432, Example 85	Epidermal growth factor receptor	Human		 11.0					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291353&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519740	381611657							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
555813	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)	XYFPWWZEPKGCCK-UHFFFAOYSA-N	50357312	IBRUTINIB::US9181263, 1::US9108973, Ref 1::US9278100, 1::US10124003, Ref. Ex. Compound 1::PCI-32765::US10711006, Compound Ibrutinib::US10919899, Ibrutinib::US10835536, Ref. Ex. Comp 1::US10793575, Example ibrutinib::US11186578, Example Ibrutinib::US11078206, Example Ibrutinib::US11407754, Example Ibrutinib::US11339167, Example Ibrutinib::US20230364079, Example Ibrutinib::US20240059694, Compound Ibrutinib::US20240139326, Compound Ibrutinib::US20240358707, Compound 13	Epidermal growth factor receptor	Human		 1.30					7.5000	25.00 C	US Patent		10.7270/Q2NS0WZR		aid1795856	US9580432	Iguchi, S; Hosoi, F; Sagara, T	2/28/2017	2/19/2019	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			24821094	136961336	91397		DB09053				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559060	COc1ccc(Nc2ncnc3cc(OC(C)C)c4OCCOc4c23)cc1[N+]([O-])=O	InChI=1S/C20H20N4O6/c1-11(2)30-16-9-13-17(19-18(16)28-6-7-29-19)20(22-10-21-13)23-12-4-5-15(27-3)14(8-12)24(25)26/h4-5,8-11H,6-7H2,1-3H3,(H,21,22,23)	FPTALKMKVJRZRL-UHFFFAOYSA-N	50171967	CHEMBL3805475::US10106508, Compound I-1	Epidermal growth factor receptor	Human		<1000							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171967	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171967&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417753	346548590		CHEMBL3805475					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559062	CC(C)Oc1cc2ncnc(Nc3ccc(F)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C19H17FN4O5/c1-10(2)29-15-8-13-16(18-17(15)27-5-6-28-18)19(22-9-21-13)23-11-3-4-12(20)14(7-11)24(25)26/h3-4,7-10H,5-6H2,1-2H3,(H,21,22,23)	JRRBFBKACYJFKD-UHFFFAOYSA-N	50171966	CHEMBL3805383::US10106508, Compound I-2	Epidermal growth factor receptor	Human		<100.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171966&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417718	346548589		CHEMBL3805383					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559064	CC(C)Oc1cc2ncnc(Nc3ccc(C)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C20H20N4O5/c1-11(2)29-16-9-14-17(19-18(16)27-6-7-28-19)20(22-10-21-14)23-13-5-4-12(3)15(8-13)24(25)26/h4-5,8-11H,6-7H2,1-3H3,(H,21,22,23)	NGGPOIUATFTCNX-UHFFFAOYSA-N	50171965	CHEMBL3805089::US10106508, Compound I-3	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171965&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417837	346548588		CHEMBL3805089					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559066	CC(C)Oc1cc2ncnc(Nc3ccc(Cl)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C19H17ClN4O5/c1-10(2)29-15-8-13-16(18-17(15)27-5-6-28-18)19(22-9-21-13)23-11-3-4-12(20)14(7-11)24(25)26/h3-4,7-10H,5-6H2,1-2H3,(H,21,22,23)	MBMAILZVMBYPRI-UHFFFAOYSA-N	50171964	CHEMBL3805177::US10106508, Compound I-4	Epidermal growth factor receptor	Human		<100.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171964&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417747	346548587		CHEMBL3805177					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559068	CC(C)Oc1cc2ncnc(Nc3ccc(F)c(c3)C#N)c2c2OCCOc12	InChI=1S/C20H17FN4O3/c1-11(2)28-16-8-15-17(19-18(16)26-5-6-27-19)20(24-10-23-15)25-13-3-4-14(21)12(7-13)9-22/h3-4,7-8,10-11H,5-6H2,1-2H3,(H,23,24,25)	TUOAPNJJVOHHOI-UHFFFAOYSA-N	50171963	CHEMBL3805949::US10106508, Compound I-5	Epidermal growth factor receptor	Human		<300							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171963	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171963&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417839	346548586		CHEMBL3805949					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559070	CC(C)Oc1cc2ncnc(Nc3ccc(C)c(c3)C#N)c2c2OCCOc12	InChI=1S/C21H20N4O3/c1-12(2)28-17-9-16-18(20-19(17)26-6-7-27-20)21(24-11-23-16)25-15-5-4-13(3)14(8-15)10-22/h4-5,8-9,11-12H,6-7H2,1-3H3,(H,23,24,25)	ZWNCQIXWOVNQET-UHFFFAOYSA-N	50171962	CHEMBL3806321::US10106508, Compound I-6	Epidermal growth factor receptor	Human		<400							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171962&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417721	346548585		CHEMBL3806321					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559072	CC(C)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2c2OCCOc12	InChI=1S/C19H17ClFN3O3/c1-10(2)27-15-8-14-16(18-17(15)25-5-6-26-18)19(23-9-22-14)24-11-3-4-13(21)12(20)7-11/h3-4,7-10H,5-6H2,1-2H3,(H,22,23,24)	VLQWKBJABCENOH-UHFFFAOYSA-N	50171961	CHEMBL3805283::US10106508, Compound I-7	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171961&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417757	346548584		CHEMBL3805283					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559074	CC(C)Oc1cc2ncnc(Nc3cccc(c3)C#C)c2c2OCCOc12	InChI=1S/C21H19N3O3/c1-4-14-6-5-7-15(10-14)24-21-18-16(22-12-23-21)11-17(27-13(2)3)19-20(18)26-9-8-25-19/h1,5-7,10-13H,8-9H2,2-3H3,(H,22,23,24)	WSTBLMCKOCVKHH-UHFFFAOYSA-N	50171960	CHEMBL3805509::US10106508, Compound I-8	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171960&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417840	346548583		CHEMBL3805509					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559076	COCCOc1cc2ncnc(Nc3ccc(OC)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C20H20N4O7/c1-27-5-6-29-16-10-13-17(19-18(16)30-7-8-31-19)20(22-11-21-13)23-12-3-4-15(28-2)14(9-12)24(25)26/h3-4,9-11H,5-8H2,1-2H3,(H,21,22,23)	KTXKGFHGOIKTLE-UHFFFAOYSA-N	50171914	CHEMBL3805491::US10106508, Compound I-9	Epidermal growth factor receptor	Human		<1000							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171914	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171914&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417722	104058090		CHEMBL3805491					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559078	COCCOc1cc2ncnc(Nc3ccc(F)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C19H17FN4O6/c1-27-4-5-28-15-9-13-16(18-17(15)29-6-7-30-18)19(22-10-21-13)23-11-2-3-12(20)14(8-11)24(25)26/h2-3,8-10H,4-7H2,1H3,(H,21,22,23)	XNPBVLWYKQZCCY-UHFFFAOYSA-N	50171915	CHEMBL3805333::US10106508, Compound I-10	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171915	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171915&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417762	104058091		CHEMBL3805333					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559080	COCCOc1cc2ncnc(Nc3ccc(C)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C20H20N4O6/c1-12-3-4-13(9-15(12)24(25)26)23-20-17-14(21-11-22-20)10-16(28-6-5-27-2)18-19(17)30-8-7-29-18/h3-4,9-11H,5-8H2,1-2H3,(H,21,22,23)	FSRMUDDPGLEQSI-UHFFFAOYSA-N	50171916	CHEMBL3805299::US10106508, Compound I-11	Epidermal growth factor receptor	Human		<100.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171916	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171916&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417841	104058092		CHEMBL3805299					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559082	COCCOc1cc2ncnc(Nc3ccc(Cl)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C19H17ClN4O6/c1-27-4-5-28-15-9-13-16(18-17(15)29-6-7-30-18)19(22-10-21-13)23-11-2-3-12(20)14(8-11)24(25)26/h2-3,8-10H,4-7H2,1H3,(H,21,22,23)	RJJLWCAGCDVRBE-UHFFFAOYSA-N	50171917	CHEMBL3806200::US10106508, Compound I-12	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171917	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171917&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417763	104058093		CHEMBL3806200					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559084	COCCOc1cc2ncnc(Nc3ccc(F)c(c3)C#N)c2c2OCCOc12	InChI=1S/C20H17FN4O4/c1-26-4-5-27-16-9-15-17(19-18(16)28-6-7-29-19)20(24-11-23-15)25-13-2-3-14(21)12(8-13)10-22/h2-3,8-9,11H,4-7H2,1H3,(H,23,24,25)	HXQGOXYMNOCPIV-UHFFFAOYSA-N	50171970	CHEMBL3805280::US10106508, Compound I-13	Epidermal growth factor receptor	Human		<500							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171970&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417842	346548593		CHEMBL3805280					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559086	COCCOc1cc2ncnc(Nc3ccc(C)c(c3)C#N)c2c2OCCOc12	InChI=1S/C21H20N4O4/c1-13-3-4-15(9-14(13)11-22)25-21-18-16(23-12-24-21)10-17(27-6-5-26-2)19-20(18)29-8-7-28-19/h3-4,9-10,12H,5-8H2,1-2H3,(H,23,24,25)	KFAUSNBTOKDOND-UHFFFAOYSA-N	293345	US10106508, Compound I-14::US10106508, Example 14 5-((5-(2-Methoxyethoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl)amino)-2-methylbenzonitrile (I-14)	Epidermal growth factor receptor	Human		<1000							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=293345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=293345&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417843	381613623							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559088	CCOC(C)Oc1cc2ncnc(Nc3ccc(OC)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C21H22N4O7/c1-4-29-12(2)32-17-10-14-18(20-19(17)30-7-8-31-20)21(23-11-22-14)24-13-5-6-16(28-3)15(9-13)25(26)27/h5-6,9-12H,4,7-8H2,1-3H3,(H,22,23,24)	AHIUTLRONNLURJ-UHFFFAOYSA-N	50171959	CHEMBL3805402::US10106508, Compound I-15	Epidermal growth factor receptor	Human		<1000							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171959&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417848	346548582		CHEMBL3805402					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559090	CCOC(C)Oc1cc2ncnc(Nc3ccc(F)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C20H19FN4O6/c1-3-28-11(2)31-16-9-14-17(19-18(16)29-6-7-30-19)20(23-10-22-14)24-12-4-5-13(21)15(8-12)25(26)27/h4-5,8-11H,3,6-7H2,1-2H3,(H,22,23,24)	KPOWUQIMHGWQLY-UHFFFAOYSA-N	50171958	CHEMBL3806172::US10106508, Compound I-16	Epidermal growth factor receptor	Human		<300							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171958	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171958&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417724	346548581		CHEMBL3806172					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559092	CCOC(C)Oc1cc2ncnc(Nc3ccc(Cl)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C20H19ClN4O6/c1-3-28-11(2)31-16-9-14-17(19-18(16)29-6-7-30-19)20(23-10-22-14)24-12-4-5-13(21)15(8-12)25(26)27/h4-5,8-11H,3,6-7H2,1-2H3,(H,22,23,24)	AGOVZOXQAPLQHF-UHFFFAOYSA-N	293348	US10106508, Compound I-17::US10106508, Example 17 N-(4-Chloro-3-nitrophenyl)-5-(1-ethoxyethoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-amine (I-17)	Epidermal growth factor receptor	Human		<300							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=293348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=293348&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417695	381613626							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559094	CCOC(C)Oc1cc2ncnc(Nc3ccc(C)c(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C21H22N4O6/c1-4-28-13(3)31-17-10-15-18(20-19(17)29-7-8-30-20)21(23-11-22-15)24-14-6-5-12(2)16(9-14)25(26)27/h5-6,9-11,13H,4,7-8H2,1-3H3,(H,22,23,24)	HWZKUDPVOFVABK-UHFFFAOYSA-N	50171957	CHEMBL3805260::US10106508, Compound I-18	Epidermal growth factor receptor	Human		<300							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171957&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417697	346548580		CHEMBL3805260					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559096	CCOC(C)Oc1cc2ncnc(Nc3ccc(F)c(c3)C#N)c2c2OCCOc12	InChI=1S/C21H19FN4O4/c1-3-27-12(2)30-17-9-16-18(20-19(17)28-6-7-29-20)21(25-11-24-16)26-14-4-5-15(22)13(8-14)10-23/h4-5,8-9,11-12H,3,6-7H2,1-2H3,(H,24,25,26)	ONRWTAOPQXIJBJ-UHFFFAOYSA-N	50171956	CHEMBL3805654::US10106508, Compound I-19	Epidermal growth factor receptor	Human		<300							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171956&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417725	346548579		CHEMBL3805654					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559098	CCOC(C)Oc1cc2ncnc(Nc3ccc(C)c(c3)C#N)c2c2OCCOc12	InChI=1S/C22H22N4O4/c1-4-27-14(3)30-18-10-17-19(21-20(18)28-7-8-29-21)22(25-12-24-17)26-16-6-5-13(2)15(9-16)11-23/h5-6,9-10,12,14H,4,7-8H2,1-3H3,(H,24,25,26)	IXEYRVNJMLKDSE-UHFFFAOYSA-N	50171955	CHEMBL3805618::US10106508, Compound I-20	Epidermal growth factor receptor	Human		<1000							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171955	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171955&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417773	346548578		CHEMBL3805618					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559100	C#Cc1cccc(Nc2ncnc3cc(OC4CCOCC4)c4OCCOc4c23)c1	InChI=1S/C23H21N3O4/c1-2-15-4-3-5-16(12-15)26-23-20-18(24-14-25-23)13-19(21-22(20)29-11-10-28-21)30-17-6-8-27-9-7-17/h1,3-5,12-14,17H,6-11H2,(H,24,25,26)	OGWFAERQSXEIRH-UHFFFAOYSA-N	50172056	CHEMBL3806145::US10106508, Compound I-21	Epidermal growth factor receptor	Human		<100.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172056&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417700	104058209		CHEMBL3806145					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559102	Fc1cc(Nc2ncnc3cc(OC4CCOCC4)c4OCCOc4c23)ccc1Cl	InChI=1S/C21H19ClFN3O4/c22-14-2-1-12(9-15(14)23)26-21-18-16(24-11-25-21)10-17(19-20(18)29-8-7-28-19)30-13-3-5-27-6-4-13/h1-2,9-11,13H,3-8H2,(H,24,25,26)	MHEIKVUKMGZIBT-UHFFFAOYSA-N	293353	US10106508, Compound I-22::US10106508, Example 22 N-(4-Chloro-3-fluorophenyl)-5-(tetrahydro-2H-pyran-4-yloxy)-2,3-dihydro-[1,4]dioxino[2,3-f]-quinazolin-10-amine (I-22)	Epidermal growth factor receptor	Human		<100.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=293353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=293353&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417726	381613631							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559104	Fc1cc(Nc2ncnc3cc(OC4CCOC4)c4OCCOc4c23)ccc1Cl	InChI=1S/C20H17ClFN3O4/c21-13-2-1-11(7-14(13)22)25-20-17-15(23-10-24-20)8-16(29-12-3-4-26-9-12)18-19(17)28-6-5-27-18/h1-2,7-8,10,12H,3-6,9H2,(H,23,24,25)	BEWVMHUKVXCLGH-UHFFFAOYSA-N	293354	US10106508, Compound I-23::US10106508, Example 23 N-(4-Chloro-3-fluorophenyl)-5-(tetrahydrofuran-3-yloxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-amine (I-23)	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=293354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=293354&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417859	381613632							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559106	C#Cc1cccc(Nc2ncnc3cc(OC4CCOC4)c4OCCOc4c23)c1	InChI=1S/C22H19N3O4/c1-2-14-4-3-5-15(10-14)25-22-19-17(23-13-24-22)11-18(29-16-6-7-26-12-16)20-21(19)28-9-8-27-20/h1,3-5,10-11,13,16H,6-9,12H2,(H,23,24,25)	ZTFLPLUQKZDWQE-UHFFFAOYSA-N	50171918	CHEMBL3806170::US10106508, Compound I-24	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171918	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171918&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417730	104058094		CHEMBL3806170					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559108	COCC(C)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2c2OCCOc12	InChI=1S/C20H19ClFN3O4/c1-11(9-26-2)29-16-8-15-17(19-18(16)27-5-6-28-19)20(24-10-23-15)25-12-3-4-14(22)13(21)7-12/h3-4,7-8,10-11H,5-6,9H2,1-2H3,(H,23,24,25)	QXBBWXNHVHJSBC-UHFFFAOYSA-N	50171954	CHEMBL3805775::US10106508, Compound I-25	Epidermal growth factor receptor	Human		<100.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171954	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171954&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417852	346548577		CHEMBL3805775					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559110	COCC(C)Oc1cc2ncnc(Nc3cccc(c3)C#C)c2c2OCCOc12	InChI=1S/C22H21N3O4/c1-4-15-6-5-7-16(10-15)25-22-19-17(23-13-24-22)11-18(29-14(2)12-26-3)20-21(19)28-9-8-27-20/h1,5-7,10-11,13-14H,8-9,12H2,2-3H3,(H,23,24,25)	AIVRNQLIHRYIBB-UHFFFAOYSA-N	50171950	CHEMBL3805584::US10106508, Compound I-26	Epidermal growth factor receptor	Human		<100.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171950&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417702	104058126		CHEMBL3805584					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559112	CC(C)Oc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c2OCCOc12	InChI=1S/C26H23ClFN3O4/c1-15(2)35-22-12-20-23(25-24(22)32-8-9-33-25)26(30-14-29-20)31-18-6-7-21(19(27)11-18)34-13-16-4-3-5-17(28)10-16/h3-7,10-12,14-15H,8-9,13H2,1-2H3,(H,29,30,31)	FLDVQQIVLMTMPN-UHFFFAOYSA-N	293358	US10106508, Compound I-27::US10106508, Example 27 N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-5-isopropoxy-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-amine (I-27)	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=293358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=293358&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417732	381613636							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559114	COc1cc2ncnc(Nc3cccc(c3)C#C)c2c2OCCOc12	InChI=1S/C19H15N3O3/c1-3-12-5-4-6-13(9-12)22-19-16-14(20-11-21-19)10-15(23-2)17-18(16)25-8-7-24-17/h1,4-6,9-11H,7-8H2,2H3,(H,20,21,22)	HYAOSZCIKQDSNH-UHFFFAOYSA-N	50172007	CHEMBL3805236::US10106508, Compound I-28	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172007&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417707	346548594		CHEMBL3805236					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559116	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2c2OCCOc12	InChI=1S/C17H13ClFN3O3/c1-23-13-7-12-14(16-15(13)24-4-5-25-16)17(21-8-20-12)22-9-2-3-11(19)10(18)6-9/h2-3,6-8H,4-5H2,1H3,(H,20,21,22)	HDTUBNQMTYLVSV-UHFFFAOYSA-N	50172008	CHEMBL3806292::US10106508, Compound I-29	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172008&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417768	346548595		CHEMBL3806292					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559118	COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2c2OCCOc12	InChI=1S/C19H17ClFN3O4/c1-25-4-5-26-15-9-14-16(18-17(15)27-6-7-28-18)19(23-10-22-14)24-11-2-3-13(21)12(20)8-11/h2-3,8-10H,4-7H2,1H3,(H,22,23,24)	GSVZKVUECPSJDL-UHFFFAOYSA-N	50171910	CHEMBL3806110::US10106508, Compound I-30	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171910	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171910&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417777	104058086		CHEMBL3806110					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559120	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2c2OCCOc12	InChI=1S/C21H19N3O4/c1-3-14-5-4-6-15(11-14)24-21-18-16(22-13-23-21)12-17(26-8-7-25-2)19-20(18)28-10-9-27-19/h1,4-6,11-13H,7-10H2,2H3,(H,22,23,24)	SYCYMWZFELUOFO-UHFFFAOYSA-N	50171911	CHEMBL3805461::US10106508, Compound I-31	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171911	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171911&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417735	104058087		CHEMBL3805461					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559122	COCCOc1cc2ncnc(Nc3ccc(F)cc3)c2c2OCCOc12	InChI=1S/C19H18FN3O4/c1-24-6-7-25-15-10-14-16(18-17(15)26-8-9-27-18)19(22-11-21-14)23-13-4-2-12(20)3-5-13/h2-5,10-11H,6-9H2,1H3,(H,21,22,23)	GHDLYUNTQJYIGQ-UHFFFAOYSA-N	50171912	CHEMBL3806005::US10106508, Compound I-32	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171912	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171912&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			127051046	104058088		CHEMBL3806005					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559124	COCCOc1cc2ncnc(Nc3cccc(OC)c3)c2c2OCCOc12	InChI=1S/C20H21N3O5/c1-24-6-7-26-16-11-15-17(19-18(16)27-8-9-28-19)20(22-12-21-15)23-13-4-3-5-14(10-13)25-2/h3-5,10-12H,6-9H2,1-2H3,(H,21,22,23)	FXBZQEFBHYYPIF-UHFFFAOYSA-N	50171913	CHEMBL3806066::US10106508, Compound I-33	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171913	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171913&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417856	104058089		CHEMBL3806066					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559126	CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2c2OCCOc12	InChI=1S/C18H15ClFN3O3/c1-2-24-14-8-13-15(17-16(14)25-5-6-26-17)18(22-9-21-13)23-10-3-4-12(20)11(19)7-10/h3-4,7-9H,2,5-6H2,1H3,(H,21,22,23)	WHZWIUHEEWZECR-UHFFFAOYSA-N	50171877	CHEMBL3806248::US10106508, Compound I-34	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171877&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417858	346548573		CHEMBL3806248					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559128	CCOc1cc2ncnc(Nc3cccc(c3)C#C)c2c2OCCOc12	InChI=1S/C20H17N3O3/c1-3-13-6-5-7-14(10-13)23-20-17-15(21-12-22-20)11-16(24-4-2)18-19(17)26-9-8-25-18/h1,5-7,10-12H,4,8-9H2,2H3,(H,21,22,23)	XODLISJMYZQRRX-UHFFFAOYSA-N	50171878	CHEMBL3805039::US10106508, Compound I-35	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171878	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171878&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417767	346548574		CHEMBL3805039					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559130	CCOc1cc2ncnc(Nc3cccc(OC)c3)c2c2OCCOc12	InChI=1S/C19H19N3O4/c1-3-24-15-10-14-16(18-17(15)25-7-8-26-18)19(21-11-20-14)22-12-5-4-6-13(9-12)23-2/h4-6,9-11H,3,7-8H2,1-2H3,(H,20,21,22)	PJADTLKXGYODKV-UHFFFAOYSA-N	50171879	CHEMBL3805774::US10106508, Compound I-36	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171879	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171879&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417781	346548575		CHEMBL3805774					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559132	CCOc1cc2ncnc(Nc3ccc(C)c(Cl)c3)c2c2OCCOc12	InChI=1S/C19H18ClN3O3/c1-3-24-15-9-14-16(18-17(15)25-6-7-26-18)19(22-10-21-14)23-12-5-4-11(2)13(20)8-12/h4-5,8-10H,3,6-7H2,1-2H3,(H,21,22,23)	XYGJPSHVCKGCKO-UHFFFAOYSA-N	50171880	CHEMBL3804868::US10106508, Compound I-37	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171880	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171880&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417706	346548576		CHEMBL3804868					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559134	CCOc1cc2ncnc(Nc3cccc(c3)[N+]([O-])=O)c2c2OCCOc12	InChI=1S/C18H16N4O5/c1-2-25-14-9-13-15(17-16(14)26-6-7-27-17)18(20-10-19-13)21-11-4-3-5-12(8-11)22(23)24/h3-5,8-10H,2,6-7H2,1H3,(H,19,20,21)	WUAZUOXCWOXJJP-UHFFFAOYSA-N	50171908	CHEMBL3805238::US10106508, Compound I-38	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171908&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417864	104058084		CHEMBL3805238					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559136	CCOc1cc2ncnc(Nc3ccc(C)cc3)c2c2OCCOc12	InChI=1S/C19H19N3O3/c1-3-23-15-10-14-16(18-17(15)24-8-9-25-18)19(21-11-20-14)22-13-6-4-12(2)5-7-13/h4-7,10-11H,3,8-9H2,1-2H3,(H,20,21,22)	CHBBYOIXEZCTDF-UHFFFAOYSA-N	50171909	CHEMBL3805859::US10106508, Compound I-39	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171909	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171909&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417709	104058085		CHEMBL3805859					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559138	Fc1ccc(Nc2ncnc3cc(OCC4CCCO4)c4OCCOc4c23)cc1Cl	InChI=1S/C21H19ClFN3O4/c22-14-8-12(3-4-15(14)23)26-21-18-16(24-11-25-21)9-17(19-20(18)29-7-6-28-19)30-10-13-2-1-5-27-13/h3-4,8-9,11,13H,1-2,5-7,10H2,(H,24,25,26)	DYSPBKSWPGPRBB-UHFFFAOYSA-N	50171969	CHEMBL3806213::US10106508, Compound I-40	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171969	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171969&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417784	346548592		CHEMBL3806213					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559140	C#Cc1cccc(Nc2ncnc3cc(OCC4CCCO4)c4OCCOc4c23)c1	InChI=1S/C23H21N3O4/c1-2-15-5-3-6-16(11-15)26-23-20-18(24-14-25-23)12-19(21-22(20)29-10-9-28-21)30-13-17-7-4-8-27-17/h1,3,5-6,11-12,14,17H,4,7-10,13H2,(H,24,25,26)	KCRPGGNYGKRTRF-UHFFFAOYSA-N	50171968	CHEMBL3805325::US10106508, Compound I-41	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171968&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417770	346548591		CHEMBL3805325					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559142	O=C1COc2cc3ncnc(Nc4cccc(c4)C#C)c3cc2N1CCCN1CCOCC1	InChI=1S/C25H25N5O3/c1-2-18-5-3-6-19(13-18)28-25-20-14-22-23(15-21(20)26-17-27-25)33-16-24(31)30(22)8-4-7-29-9-11-32-12-10-29/h1,3,5-6,13-15,17H,4,7-12,16H2,(H,26,27,28)	BWQQOASTOBPYOA-UHFFFAOYSA-N	50154255	CHEMBL3774926::US10106508, Compound II-1	Epidermal growth factor receptor	Human		<50.0							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154255	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154255&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417788	104042003		CHEMBL3774926					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559144	Fc1ccc(Nc2ncnc3cc4OCC(=O)N(CCCN5CCOCC5)c4cc23)cc1Cl	InChI=1S/C23H23ClFN5O3/c24-17-10-15(2-3-18(17)25)28-23-16-11-20-21(12-19(16)26-14-27-23)33-13-22(31)30(20)5-1-4-29-6-8-32-9-7-29/h2-3,10-12,14H,1,4-9,13H2,(H,26,27,28)	OTFQIRDSLHXCMT-UHFFFAOYSA-N	50154284	CHEMBL3775664::US10106508, Compound II-2	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154284	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154284&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417712	340133298		CHEMBL3775664					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559146	Cc1ccc(Nc2ncnc3cc4OCC(=O)N(CCCN5CCOCC5)c4cc23)cc1Cl	InChI=1S/C24H26ClN5O3/c1-16-3-4-17(11-19(16)25)28-24-18-12-21-22(13-20(18)26-15-27-24)33-14-23(31)30(21)6-2-5-29-7-9-32-10-8-29/h3-4,11-13,15H,2,5-10,14H2,1H3,(H,26,27,28)	LNWBHCXDLOKRTA-UHFFFAOYSA-N	50154277	CHEMBL3774578::US10106508, Compound II-3	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154277	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154277&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417787	340133291		CHEMBL3774578					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559148	COc1cccc(Nc2ncnc3cc4OCC(=O)N(CCCN5CCOCC5)c4cc23)c1	InChI=1S/C24H27N5O4/c1-31-18-5-2-4-17(12-18)27-24-19-13-21-22(14-20(19)25-16-26-24)33-15-23(30)29(21)7-3-6-28-8-10-32-11-9-28/h2,4-5,12-14,16H,3,6-11,15H2,1H3,(H,25,26,27)	WOHFHMIOTRFMRH-UHFFFAOYSA-N	50154286	CHEMBL3774910::US10106508, Compound II-4	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154286	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154286&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417740	340133300		CHEMBL3774910					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559150	COc1ccc(Nc2ncnc3cc4OCC(=O)N(CCCN5CCOCC5)c4cc23)cc1OC	InChI=1S/C25H29N5O5/c1-32-21-5-4-17(12-23(21)33-2)28-25-18-13-20-22(14-19(18)26-16-27-25)35-15-24(31)30(20)7-3-6-29-8-10-34-11-9-29/h4-5,12-14,16H,3,6-11,15H2,1-2H3,(H,26,27,28)	JMISUVUVJZZXEG-UHFFFAOYSA-N	50154278	CHEMBL3775372::US10106508, Compound II-5	Epidermal growth factor receptor	Human		<200							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154278	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154278&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122417713	340133292		CHEMBL3775372					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
559152	COc1cc2c(cc1OCCCN3CCOCC3)c(ncn2)Nc4ccc(c(c4)Cl)F	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	ZD1839::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::cid_123631::CHEMBL939::GEFITINIB::Iressa::US9416123, Gefitinib::US10106508, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::US10507209, Compound Gefitinib::WO2022090481, Example gefitinib	Epidermal growth factor receptor	Human		 6.30							US Patent		10.7270/Q26M38VB		aid1795889	US10106508	Sheng, W; Yang, L; Pan, Z	10/23/2018	2/24/2019	Beijing Scitech-Mq Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	IRE	2ITZ,2ITY,2ITO,5Y7Z,4WKQ,4I22,5Y80,3UG2	123631	8035066	49668	CHEMBL939	DB00317				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593812	CC(C)(C)OC(=O)N1CCC[C@H](C1)n1ccc2cc(cc(F)c2c1=O)C1CC1 |r|	InChI=1S/C22H27FN2O3/c1-22(2,3)28-21(27)24-9-4-5-17(13-24)25-10-8-15-11-16(14-6-7-14)12-18(23)19(15)20(25)26/h8,10-12,14,17H,4-7,9,13H2,1-3H3	DJISWDHMBIMVQR-UHFFFAOYSA-N	309576	US9656988, Example 47::(R)-3-(3-(6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2(1H)-yl)piperidin-1-yl)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309576&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115106	382365637							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593815	NC(=O)c1nnc(nc1Nc1ccc(cc1)C(=O)N1CCOCC1)N1CCC[C@H](C1)Oc1nccc2cc(cc(F)c12)C1CC1 |r|	InChI=1S/C32H33FN8O4/c33-25-17-22(19-3-4-19)16-21-9-10-35-30(26(21)25)45-24-2-1-11-41(18-24)32-37-29(27(28(34)42)38-39-32)36-23-7-5-20(6-8-23)31(43)40-12-14-44-15-13-40/h5-10,16-17,19,24H,1-4,11-15,18H2,(H2,34,42)(H,36,37,39)	MHSIPPABRWKFFG-UHFFFAOYSA-N	309577	US9656988, Example 48::(R)-3-(3-(6-cyclopropyl-8-fluoroisoquinolin-1-yloxy)piperidin-1-yl)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309577&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114606	382365638							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593818	CC(C)(C)c1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)S(C)(=O)=O)n1 |r|	InChI=1S/C27H33N7O4S/c1-27(2,3)18-9-7-17(8-10-18)25(36)30-20-6-5-15-34(16-20)26-31-24(22(23(28)35)32-33-26)29-19-11-13-21(14-12-19)39(4,37)38/h7-14,20H,5-6,15-16H2,1-4H3,(H2,28,35)(H,30,36)(H,29,31,33)	MDQRIUQNZANBTI-UHFFFAOYSA-N	309584	US9656988, Example 55::(R)-3-(3-(4-tert-butylbenzamido)piperidin-1-yl)-5-(4-(methylsulfonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309584&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114509	382365645							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593822	NC(=O)c1nnc(N[C@@H]2CCN(C2)C(=O)C=C)nc1Nc1ccc(cc1)C(=O)N1CCOCC1 |r|	InChI=1S/C22H26N8O4/c1-2-17(31)30-8-7-16(13-30)25-22-26-20(18(19(23)32)27-28-22)24-15-5-3-14(4-6-15)21(33)29-9-11-34-12-10-29/h2-6,16H,1,7-13H2,(H2,23,32)(H2,24,25,26,28)	HQWCPDUIKCIHEE-UHFFFAOYSA-N	309599	(R)-3-(1-acryloylpyrrolidin-3-ylamino)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide ::US9656988, Example 70::BDBM309601	Epidermal growth factor receptor	Human		 55							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309599	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309599&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114900	382365660							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593826	CN([C@@H]1CCCN(C1)C(=O)C=C)c1cnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C25H31N7O4/c1-3-21(33)32-10-4-5-19(16-32)30(2)20-15-27-22(23(26)34)24(29-20)28-18-8-6-17(7-9-18)25(35)31-11-13-36-14-12-31/h3,6-9,15,19H,1,4-5,10-14,16H2,2H3,(H2,26,34)(H,28,29)	IACPUILVLDGVIT-UHFFFAOYSA-N	309604	US9656988, Example 74::(R)-5-((1-acryloylpiperidin-3-yl)(methyl)amino)-3-(4-(morpholine-4-carbonyl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309604&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114761	382365665							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593830	CN(C)C\C=C\C(=O)N1CCC[C@H](C1)N(C)c1cnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C28H38N8O4/c1-33(2)12-5-7-24(37)36-13-4-6-22(19-36)34(3)23-18-30-25(26(29)38)27(32-23)31-21-10-8-20(9-11-21)28(39)35-14-16-40-17-15-35/h5,7-11,18,22H,4,6,12-17,19H2,1-3H3,(H2,29,38)(H,31,32)	JETKONUWSRIYFR-UHFFFAOYSA-N	309605	US9656988, Example 75::(R,E)-5-((1-(4-(dimethylamino)but-2-enoyl)piperidin-3-yl)(methyl)amino)-3-(4-(morpholine-4-carbonyl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309605	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309605&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114641	382365666							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593834	NC(=O)c1nnc(nc1Nc1ccc(cc1)C(=O)N1CCOCC1)N1CCC[C@H](C1)NC(=O)Nc1ccccc1 |r|	InChI=1S/C27H31N9O4/c28-23(37)22-24(29-20-10-8-18(9-11-20)25(38)35-13-15-40-16-14-35)32-26(34-33-22)36-12-4-7-21(17-36)31-27(39)30-19-5-2-1-3-6-19/h1-3,5-6,8-11,21H,4,7,12-17H2,(H2,28,37)(H,29,32,34)(H2,30,31,39)	VTYADNBTOGMKIP-UHFFFAOYSA-N	309608	US9656988, Example 78::((R)-5-(4-(morpholine-4-carbonyl)phenylamino)-3-(3-(3-phenylureido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309608&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114964	382365669							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593841	CN(C)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C23H31N9O4/c1-30(2)23(35)26-17-4-3-9-32(14-17)22-27-20(18(19(24)33)28-29-22)25-16-7-5-15(6-8-16)21(34)31-10-12-36-13-11-31/h5-8,17H,3-4,9-14H2,1-2H3,(H2,24,33)(H,26,35)(H,25,27,29)	NVKPTCAQJDUBOS-UHFFFAOYSA-N	309611	US9656988, Example 81::(R)-3-(3-(3,3-dimethylureido)piperidin-1-yl)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309611	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309611&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114736	382365672							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593850	NC(=O)c1nnc(nc1Nc1ccc(cc1)C(=O)N1CCOCC1)N1CCC[C@H](C1)NC(=O)c1ccc2ccccc2n1 |r|	InChI=1S/C30H31N9O4/c31-26(40)25-27(32-21-10-7-20(8-11-21)29(42)38-14-16-43-17-15-38)35-30(37-36-25)39-13-3-5-22(18-39)33-28(41)24-12-9-19-4-1-2-6-23(19)34-24/h1-2,4,6-12,22H,3,5,13-18H2,(H2,31,40)(H,33,41)(H,32,35,37)	CNIYWDNGBCSRGL-UHFFFAOYSA-N	309614	US9656988, Example 84::(R)&#151;N-(1-(6-carbamoyl-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazin-3-yl)piperidin-3-yl)quinoline-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309614	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309614&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115028	382365675							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593853	NC(=O)c1nnc(nc1Nc1ccc(cc1)C(=O)N1CCOCC1)N1CCC[C@H](C1)NC(=O)c1ccc2ncccc2c1 |r|	InChI=1S/C30H31N9O4/c31-26(40)25-27(33-22-8-5-19(6-9-22)29(42)38-13-15-43-16-14-38)35-30(37-36-25)39-12-2-4-23(18-39)34-28(41)21-7-10-24-20(17-21)3-1-11-32-24/h1,3,5-11,17,23H,2,4,12-16,18H2,(H2,31,40)(H,34,41)(H,33,35,37)	PLKXLSABUWNGOL-UHFFFAOYSA-N	309615	US9656988, Example 85::(R)&#151;N-(1-(6-carbamoyl-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazin-3-yl)piperidin-3-yl)quinoline-6-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309615	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309615&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114678	382365676							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593856	NC(=O)c1nnc(nc1Nc1ccc(cc1)C(=O)N1CCOCC1)N1CCC[C@H](C1)NC(=O)c1ccc(OCC(F)(F)F)cc1 |r|	InChI=1S/C29H31F3N8O5/c30-29(31,32)17-45-22-9-5-18(6-10-22)26(42)35-21-2-1-11-40(16-21)28-36-25(23(24(33)41)37-38-28)34-20-7-3-19(4-8-20)27(43)39-12-14-44-15-13-39/h3-10,21H,1-2,11-17H2,(H2,33,41)(H,35,42)(H,34,36,38)	YHEYPWDORXURJK-UHFFFAOYSA-N	309616	US9656988, Example 86::(R)-5-(4-(morpholine-4-carbonyl)phenylamino)-3-(3-(4-(2,2,2-trifluoroethoxy)benzamido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309616&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114453	382365677							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593859	Cc1ccc(s1)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C26H30N8O4S/c1-16-4-9-20(39-16)24(36)29-19-3-2-10-34(15-19)26-30-23(21(22(27)35)31-32-26)28-18-7-5-17(6-8-18)25(37)33-11-13-38-14-12-33/h4-9,19H,2-3,10-15H2,1H3,(H2,27,35)(H,29,36)(H,28,30,32)	NQHRIAKNZJDTIS-UHFFFAOYSA-N	309617	US9656988, Example 87::(R)-3-(3-(5-methylthiophene-2-carboxamido)piperidin-1-yl)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309617&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114601	382365678							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593888	CCN(CC)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C25H35N9O4/c1-3-32(4-2)25(37)28-19-6-5-11-34(16-19)24-29-22(20(21(26)35)30-31-24)27-18-9-7-17(8-10-18)23(36)33-12-14-38-15-13-33/h7-10,19H,3-6,11-16H2,1-2H3,(H2,26,35)(H,28,37)(H,27,29,31)	ANBAGHNOTKPXIR-UHFFFAOYSA-N	309630	US9656988, Example 99::(R)-3-(3-(3,3-diethylureido)piperidin-1-yl)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309630	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309630&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114804	382365691							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593903	COC(=O)c1ccccc1CN[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C29H34N8O5/c1-41-28(40)23-7-3-2-5-20(23)17-31-22-6-4-12-37(18-22)29-33-26(24(25(30)38)34-35-29)32-21-10-8-19(9-11-21)27(39)36-13-15-42-16-14-36/h2-3,5,7-11,22,31H,4,6,12-18H2,1H3,(H2,30,38)(H,32,33,35)	MZMWNDRVYSIOHF-UHFFFAOYSA-N	309635	US9656988, Example 104::(R)-5-(4-(morpholine-4-carbonyl)phenylamino)-3-(3-(1-oxoisoindolin-2-yl)piperidin-1-yl)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309635	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309635&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118133408	382365696							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593906	CC#CC(=O)N1CCC[C@H](C1)Nc1nnc(C(N)=O)c(Nc2ccc(cc2)S(C)(=O)=O)n1 |r|	InChI=1S/C20H23N7O4S/c1-3-5-16(28)27-11-4-6-14(12-27)23-20-24-19(17(18(21)29)25-26-20)22-13-7-9-15(10-8-13)32(2,30)31/h7-10,14H,4,6,11-12H2,1-2H3,(H2,21,29)(H2,22,23,24,26)	OTPKESFCTVIJSI-UHFFFAOYSA-N	309636	US9656988, Example 105::(R)-3-(1-but-2-ynoylpiperidin-3-ylamino)-5-(4-(methylsulfonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309636&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114905	382365697							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593910	CN(C)C\C=C\C(=O)N1CCC[C@H](C1)Nc1nnc(C(N)=O)c(Nc2ccc(cc2)S(C)(=O)=O)n1 |r|	InChI=1S/C22H30N8O4S/c1-29(2)12-5-7-18(31)30-13-4-6-16(14-30)25-22-26-21(19(20(23)32)27-28-22)24-15-8-10-17(11-9-15)35(3,33)34/h5,7-11,16H,4,6,12-14H2,1-3H3,(H2,23,32)(H2,24,25,26,28)	QOXFMUBWQHGRRX-UHFFFAOYSA-N	309637	US9656988, Example 106::(R,E)-3-(1-(4-(dimethylamino)but-2-enoyl)piperidin-3-ylamino)-5-(4-(methylsulfonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309637&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114638	382365698							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593914	CN(C\C=C\C(=O)N1CCC[C@H](C1)Nc1nnc(C(N)=O)c(Nc2ccc(cc2)S(C)(=O)=O)n1)C1CC1 |r|	InChI=1S/C24H32N8O4S/c1-31(18-9-10-18)13-4-6-20(33)32-14-3-5-17(15-32)27-24-28-23(21(22(25)34)29-30-24)26-16-7-11-19(12-8-16)37(2,35)36/h4,6-8,11-12,17-18H,3,5,9-10,13-15H2,1-2H3,(H2,25,34)(H2,26,27,28,30)	WKVGPPQKZYTFPL-UHFFFAOYSA-N	309638	US9656988, Example 107::(R,E)-3-(1-(4-(cyclopropyl(methyl)amino)but-2-enoyl)piperidin-3-ylamino)-5-(4-(methylsulfonyl)phenylamino)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309638	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309638&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115087	382365699							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593924	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C#N)c(Cl)n1 |r|	InChI=1S/C18H18ClN5O2/c1-26-14-6-4-12(5-7-14)18(25)22-13-3-2-8-24(11-13)16-10-21-15(9-20)17(19)23-16/h4-7,10,13H,2-3,8,11H2,1H3,(H,22,25)	FSSAKDDLOAFZIN-UHFFFAOYSA-N	309641	US9656988, Example 110::(R)-5-(3-(4-methoxybenzamido)piperidin-1-yl)-3-(4-methoxyphenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309641&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115072	382365702							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593931	COCCOc1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)c2ccc(OC)cc2)cc1 |r|	InChI=1S/C27H32N6O5/c1-36-14-15-38-22-11-7-19(8-12-22)30-26-24(25(28)34)29-16-23(32-26)33-13-3-4-20(17-33)31-27(35)18-5-9-21(37-2)10-6-18/h5-12,16,20H,3-4,13-15,17H2,1-2H3,(H2,28,34)(H,30,32)(H,31,35)	QHPZSFVJMRXRCS-UHFFFAOYSA-N	309643	US9656988, Example 112::(R)-5-(3-(4-methoxybenzamido)piperidin-1-yl)-3-(4-(2-methoxyethoxy)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309643	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309643&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114789	382365704							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593952	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc3ncccc3c2)n1 |r|	InChI=1S/C27H27N7O3/c1-37-21-9-6-17(7-10-21)27(36)32-20-5-3-13-34(16-20)23-15-30-24(25(28)35)26(33-23)31-19-8-11-22-18(14-19)4-2-12-29-22/h2,4,6-12,14-15,20H,3,5,13,16H2,1H3,(H2,28,35)(H,31,33)(H,32,36)	FQXOARDOINUDGJ-UHFFFAOYSA-N	309651	US9656988, Example 120::(R)-5-(3-(4-methoxybenzamido)piperidin-1-yl)-3-(quinolin-6-ylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309651&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114717	382365712							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593956	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc3ncsc3c2)n1 |r|	InChI=1S/C25H25N7O3S/c1-35-18-7-4-15(5-8-18)25(34)30-17-3-2-10-32(13-17)21-12-27-22(23(26)33)24(31-21)29-16-6-9-19-20(11-16)36-14-28-19/h4-9,11-12,14,17H,2-3,10,13H2,1H3,(H2,26,33)(H,29,31)(H,30,34)	ZWLDIDDDVGQBAX-UHFFFAOYSA-N	309652	US9656988, Example 121::(R)-3-(benzo[d]thiazol-6-ylamino)-5-(3-(4-methoxybenzamido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309652	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309652&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114613	382365713							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593966	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(nc2)N2CCOCC2)n1 |r|	InChI=1S/C27H32N8O4/c1-38-21-7-4-18(5-8-21)27(37)32-20-3-2-10-35(17-20)23-16-30-24(25(28)36)26(33-23)31-19-6-9-22(29-15-19)34-11-13-39-14-12-34/h4-9,15-16,20H,2-3,10-14,17H2,1H3,(H2,28,36)(H,31,33)(H,32,37)	AWMGSTACIVFGIG-UHFFFAOYSA-N	309655	US9656988, Example 124::(R)-5-(3-(4-methoxybenzamido)piperidin-1-yl)-3-(6-morpholinopyridin-3-ylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309655	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309655&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114793	382365716							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593982	CN1CCN(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)c2ccc(cc2)C(C)(C)C)cc1 |r|	InChI=1S/C32H42N8O2/c1-32(2,3)23-9-7-22(8-10-23)31(42)36-25-6-5-15-40(21-25)27-20-34-28(29(33)41)30(37-27)35-24-11-13-26(14-12-24)39-18-16-38(4)17-19-39/h7-14,20,25H,5-6,15-19,21H2,1-4H3,(H2,33,41)(H,35,37)(H,36,42)	ITGUQNXUVZYULD-UHFFFAOYSA-N	309660	US9656988, Example 129::(R)-5-(3-(4-tert-butylbenzamido)piperidin-1-yl)-3-(4-(4-methylpiperazin-1-yl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309660	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309660&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114831	382365721							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593986	CN1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)c2ccc(cc2)C(C)(C)C)cc1 |r|	InChI=1S/C33H43N7O2/c1-33(2,3)25-11-7-24(8-12-25)32(42)37-27-6-5-17-40(21-27)28-20-35-29(30(34)41)31(38-28)36-26-13-9-22(10-14-26)23-15-18-39(4)19-16-23/h7-14,20,23,27H,5-6,15-19,21H2,1-4H3,(H2,34,41)(H,36,38)(H,37,42)	CBVUEAAQUJJHEA-UHFFFAOYSA-N	309661	US9656988, Example 130::(R)-5-(3-(4-tert-butylbenzamido)piperidin-1-yl)-3-(4-(1-methylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309661	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309661&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114774	382365722							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593991	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(C)CC2)n1 |r|	InChI=1S/C30H37N7O3/c1-36-16-13-21(14-17-36)20-5-9-23(10-6-20)33-29-27(28(31)38)32-18-26(35-29)37-15-3-4-24(19-37)34-30(39)22-7-11-25(40-2)12-8-22/h5-12,18,21,24H,3-4,13-17,19H2,1-2H3,(H2,31,38)(H,33,35)(H,34,39)	BWYRLNXYRATYLM-UHFFFAOYSA-N	309662	US9656988, Example 131::(R)-5-(3-(4-methoxybenzamido)piperidin-1-yl)-3-(4-(1-methylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309662&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114818	382365723							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
593995	CCN1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)c2ccc(OC)cc2)cc1 |r|	InChI=1S/C31H39N7O3/c1-3-37-17-14-22(15-18-37)21-6-10-24(11-7-21)34-30-28(29(32)39)33-19-27(36-30)38-16-4-5-25(20-38)35-31(40)23-8-12-26(41-2)13-9-23/h6-13,19,22,25H,3-5,14-18,20H2,1-2H3,(H2,32,39)(H,34,36)(H,35,40)	SUIOCBDUXFNRHM-UHFFFAOYSA-N	309663	US9656988, Example 132::(R)-3-(4-(1-ethylpiperidin-4-yl)phenylamino)-5-(3-(4-methoxybenzamido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309663	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309663&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115130	382365724							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594000	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CC2)n1 |r|	InChI=1S/C32H39N7O3/c1-42-27-12-6-23(7-13-27)32(41)36-25-3-2-16-39(20-25)28-19-34-29(30(33)40)31(37-28)35-24-8-4-21(5-9-24)22-14-17-38(18-15-22)26-10-11-26/h4-9,12-13,19,22,25-26H,2-3,10-11,14-18,20H2,1H3,(H2,33,40)(H,35,37)(H,36,41)	JRKSMTJDASLJBM-UHFFFAOYSA-N	309664	US9656988, Example 133::(R)-3-(4-(1-cyclopropylpiperidin-4-yl)phenylamino)-5-(3-(4-methoxybenzamido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309664&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114778	382365725							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594021	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C(C)=O)n1 |r|	InChI=1S/C31H37N7O4/c1-20(39)37-16-13-22(14-17-37)21-5-9-24(10-6-21)34-30-28(29(32)40)33-18-27(36-30)38-15-3-4-25(19-38)35-31(41)23-7-11-26(42-2)12-8-23/h5-12,18,22,25H,3-4,13-17,19H2,1-2H3,(H2,32,40)(H,34,36)(H,35,41)	OMYRAQFRZOHJIJ-UHFFFAOYSA-N	309670	US9656988, Example 139::(R)-3-(4-(1-acetylpiperidin-4-yl)phenylamino)-5-(3-(4-methoxybenzamido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309670	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309670&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114460	382365731							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594032	COc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C(=O)N(C)C)n1 |r|	InChI=1S/C32H40N8O4/c1-38(2)32(43)39-17-14-22(15-18-39)21-6-10-24(11-7-21)35-30-28(29(33)41)34-19-27(37-30)40-16-4-5-25(20-40)36-31(42)23-8-12-26(44-3)13-9-23/h6-13,19,22,25H,4-5,14-18,20H2,1-3H3,(H2,33,41)(H,35,37)(H,36,42)	YQFIGYCAMFOXGF-UHFFFAOYSA-N	309673	US9656988, Example 142::(R)-3-(4-(1-(dimethylcarbamoyl)piperidin-4-yl)phenylamino)-5-(3-(4-methoxybenzamido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309673	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309673&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115277	382365734							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594049	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C=O)N1CCC[C@H](C1)NC(=O)N1CCCCC1 |r|	InChI=1S/C28H38N8O3/c29-26(38)25-27(31-22-8-6-20(7-9-22)21-10-15-34(19-37)16-11-21)33-24(17-30-25)36-14-4-5-23(18-36)32-28(39)35-12-2-1-3-13-35/h6-9,17,19,21,23H,1-5,10-16,18H2,(H2,29,38)(H,31,33)(H,32,39)	UKKRWUIIZPVZDM-UHFFFAOYSA-N	309679	US9656988, Example 148::(R)-3-(4-(1-formylpiperidin-4-yl)phenylamino)-5-(3-(piperidine-1-carboxamido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309679	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309679&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114464	382365740							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594053	CCC(=O)N1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)N2CCCCC2)cc1 |r|	InChI=1S/C30H42N8O3/c1-2-26(39)36-17-12-22(13-18-36)21-8-10-23(11-9-21)33-29-27(28(31)40)32-19-25(35-29)38-16-6-7-24(20-38)34-30(41)37-14-4-3-5-15-37/h8-11,19,22,24H,2-7,12-18,20H2,1H3,(H2,31,40)(H,33,35)(H,34,41)	MQOLBQBIISQQEU-UHFFFAOYSA-N	309680	US9656988, Example 149::(R)-5-(3-(piperidine-1-carboxamido)piperidin-1-yl)-3-(4-(1-propionylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309680	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309680&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114450	382365741							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594056	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C(=O)CC#N)N1CCC[C@H](C1)NC(=O)N1CCCCC1 |r|	InChI=1S/C30H39N9O3/c31-13-10-26(40)37-17-11-22(12-18-37)21-6-8-23(9-7-21)34-29-27(28(32)41)33-19-25(36-29)39-16-4-5-24(20-39)35-30(42)38-14-2-1-3-15-38/h6-9,19,22,24H,1-5,10-12,14-18,20H2,(H2,32,41)(H,34,36)(H,35,42)	GJVRHNMHPUDIPK-UHFFFAOYSA-N	309681	US9656988, Example 150::(R)-3-(4-(1-(2-cyanoacetyl)piperidin-4-yl)phenylamino)-5-(3-(piperidine-1-carboxamido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309681	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309681&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114619	382365742							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594061	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)S(C)(=O)=O)n1 |r|	InChI=1S/C20H27N7O4S/c1-26(2)20(29)24-14-5-4-10-27(12-14)16-11-22-17(18(21)28)19(25-16)23-13-6-8-15(9-7-13)32(3,30)31/h6-9,11,14H,4-5,10,12H2,1-3H3,(H2,21,28)(H,23,25)(H,24,29)	UYPQWNIVKFFUII-UHFFFAOYSA-N	309682	US9656988, Example 151::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(methylsulfonyl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309682	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309682&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115245	382365743							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594066	CCC(=O)N1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)N(C)C)cc1 |r|	InChI=1S/C27H38N8O3/c1-4-23(36)34-14-11-19(12-15-34)18-7-9-20(10-8-18)30-26-24(25(28)37)29-16-22(32-26)35-13-5-6-21(17-35)31-27(38)33(2)3/h7-10,16,19,21H,4-6,11-15,17H2,1-3H3,(H2,28,37)(H,30,32)(H,31,38)	OIBIOFXJAJUALW-UHFFFAOYSA-N	309683	US9656988, Example 152::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-propionylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309683	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309683&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114581	382365744							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594071	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C(=O)CC#N)n1 |r|	InChI=1S/C27H35N9O3/c1-34(2)27(39)32-21-4-3-13-36(17-21)22-16-30-24(25(29)38)26(33-22)31-20-7-5-18(6-8-20)19-10-14-35(15-11-19)23(37)9-12-28/h5-8,16,19,21H,3-4,9-11,13-15,17H2,1-2H3,(H2,29,38)(H,31,33)(H,32,39)	NIZWHJVGPCZQDZ-UHFFFAOYSA-N	309684	US9656988, Example 153::(R)-3-(4-(1-(2-cyanoacetyl)piperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309684	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309684&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114927	382365745							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594076	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCNCC2)n1 |r|	InChI=1S/C24H34N8O2/c1-31(2)24(34)29-19-4-3-13-32(15-19)20-14-27-21(22(25)33)23(30-20)28-18-7-5-16(6-8-18)17-9-11-26-12-10-17/h5-8,14,17,19,26H,3-4,9-13,15H2,1-2H3,(H2,25,33)(H,28,30)(H,29,34)	UFUMSQFMKPHFGV-UHFFFAOYSA-N	309685	US9656988, Example 154::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(piperidin-4-yl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309685&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114627	382365746							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594081	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1 |r|	InChI=1S/C29H42N8O2/c1-35(2)29(39)33-23-6-5-15-37(19-23)25-18-31-26(27(30)38)28(34-25)32-22-11-9-20(10-12-22)21-13-16-36(17-14-21)24-7-3-4-8-24/h9-12,18,21,23-24H,3-8,13-17,19H2,1-2H3,(H2,30,38)(H,32,34)(H,33,39)	WWFQRNJUOGZJQS-UHFFFAOYSA-N	309686	US9656988, Example 155::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309686&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115195	382365747							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594085	CN(C\C=C\C(=O)N1CCC[C@H](C1)N(C)c1cnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1)C1CC1 |r|	InChI=1S/C30H40N8O4/c1-35(23-11-12-23)13-4-6-26(39)38-14-3-5-24(20-38)36(2)25-19-32-27(28(31)40)29(34-25)33-22-9-7-21(8-10-22)30(41)37-15-17-42-18-16-37/h4,6-10,19,23-24H,3,5,11-18,20H2,1-2H3,(H2,31,40)(H,33,34)	QLZTUVXTBKYYCH-UHFFFAOYSA-N	309687	US9656988, Example 156::(R,E)-5-((1-(4-(cyclopropyhmethyl)amino)but-2-enoyl)piperidin-3-yl)(methyl)amino)-3-(4-(morpholine-4-carbonyl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309687&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114625	382365748							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594089	CC#CC(=O)N1CCC[C@H](C1)N(C)c1cnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C26H31N7O4/c1-3-5-22(34)33-11-4-6-20(17-33)31(2)21-16-28-23(24(27)35)25(30-21)29-19-9-7-18(8-10-19)26(36)32-12-14-37-15-13-32/h7-10,16,20H,4,6,11-15,17H2,1-2H3,(H2,27,35)(H,29,30)	VIIJKJPJUMTZGU-UHFFFAOYSA-N	309688	US9656988, Example 157::(R)-5-((1-but-2-ynoylpiperidin-3-yl)(methyl)amino)-3-(4-(morpholine-4-carbonyl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309688	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309688&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115451	382365749							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594093	CCOc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)[N+]#[C-])n1 |r|	InChI=1S/C25H26N8O3/c1-3-36-20-12-6-16(7-13-20)24(35)29-19-5-4-14-33(15-19)25-30-23(21(22(26)34)31-32-25)28-18-10-8-17(27-2)9-11-18/h6-13,19H,3-5,14-15H2,1H3,(H2,26,34)(H,29,35)(H,28,30,32)	MOGCBYGBWQITBV-UHFFFAOYSA-N	309690	US9656988, Example 159::(R)-5-(4-cyanophenylamino)-3-(3-(4-ethoxybenzamido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide 	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309690	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309690&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			123704628	382365751							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594109	CN1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)OC(C)(C)C)cc1 |r|	InChI=1S/C27H39N7O3/c1-27(2,3)37-26(36)31-21-6-5-13-34(17-21)22-16-29-23(24(28)35)25(32-22)30-20-9-7-18(8-10-20)19-11-14-33(4)15-12-19/h7-10,16,19,21H,5-6,11-15,17H2,1-4H3,(H2,28,35)(H,30,32)(H,31,36)	BILNBAJWFVQGPG-UHFFFAOYSA-N	309696	US9656988, Example 165::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-methylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309696	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309696&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114512	382365757							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594113	CCN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(C)CC2)n1 |r|	InChI=1S/C26H38N8O2/c1-4-33(3)26(36)30-21-6-5-13-34(17-21)22-16-28-23(24(27)35)25(31-22)29-20-9-7-18(8-10-20)19-11-14-32(2)15-12-19/h7-10,16,19,21H,4-6,11-15,17H2,1-3H3,(H2,27,35)(H,29,31)(H,30,36)	QILQLPCWLHMKEX-UHFFFAOYSA-N	309697	US9656988, Example 166::(R)-5-(3-(3-ethyl-3-methylureido)piperidin-1-yl)-3-(4-(1-methylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309697	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309697&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115253	382365758							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594117	CCN(CC)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(C)CC2)n1 |r|	InChI=1S/C27H40N8O2/c1-4-34(5-2)27(37)31-22-7-6-14-35(18-22)23-17-29-24(25(28)36)26(32-23)30-21-10-8-19(9-11-21)20-12-15-33(3)16-13-20/h8-11,17,20,22H,4-7,12-16,18H2,1-3H3,(H2,28,36)(H,30,32)(H,31,37)	SFKPBKWXQBFJHD-UHFFFAOYSA-N	309698	US9656988, Example 167::(R)-5-(3-(3,3-diethylureido)piperidin-1-yl)-3-(4-(1-methylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309698	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309698&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114670	382365759							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594121	CN1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)c2ccc(F)cc2)cc1 |r|	InChI=1S/C29H34FN7O2/c1-36-15-12-20(13-16-36)19-6-10-23(11-7-19)33-28-26(27(31)38)32-17-25(35-28)37-14-2-3-24(18-37)34-29(39)21-4-8-22(30)9-5-21/h4-11,17,20,24H,2-3,12-16,18H2,1H3,(H2,31,38)(H,33,35)(H,34,39)	KJNOYLPRXXIEBI-UHFFFAOYSA-N	309699	US9656988, Example 168::(R)-5-(3-(4-fluorobenzamido)piperidin-1-yl)-3-(4-(1-methylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309699	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309699&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114857	382365760							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594126	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C(=O)N(C)C)n1 |r|	InChI=1S/C27H39N9O3/c1-33(2)26(38)31-21-6-5-13-36(17-21)22-16-29-23(24(28)37)25(32-22)30-20-9-7-18(8-10-20)19-11-14-35(15-12-19)27(39)34(3)4/h7-10,16,19,21H,5-6,11-15,17H2,1-4H3,(H2,28,37)(H,30,32)(H,31,38)	QFKFKXOBHBVFQK-UHFFFAOYSA-N	309701	US9656988, Example 170::(R)-3-(4-(1-(dimethylcarbamoyl)piperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309701&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114611	382365762							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594131	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C(=O)C2CC2)n1 |r|	InChI=1S/C28H38N8O3/c1-34(2)28(39)32-22-4-3-13-36(17-22)23-16-30-24(25(29)37)26(33-23)31-21-9-7-18(8-10-21)19-11-14-35(15-12-19)27(38)20-5-6-20/h7-10,16,19-20,22H,3-6,11-15,17H2,1-2H3,(H2,29,37)(H,31,33)(H,32,39)	DJBQGUXCAGMWNN-UHFFFAOYSA-N	309702	US9656988, Example 171::(R)-3-(4-(1-(cyclopropanecarbonyl)piperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309702&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115394	382365763							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594136	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)S(C)(=O)=O)n1 |r|	InChI=1S/C25H36N8O4S/c1-31(2)25(35)29-20-5-4-12-32(16-20)21-15-27-22(23(26)34)24(30-21)28-19-8-6-17(7-9-19)18-10-13-33(14-11-18)38(3,36)37/h6-9,15,18,20H,4-5,10-14,16H2,1-3H3,(H2,26,34)(H,28,30)(H,29,35)	KSUUWWFAWIJYCZ-UHFFFAOYSA-N	309703	US9656988, Example 172::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-(methylsulfonyl)piperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309703	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309703&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114697	382365764							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594144	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)c2ccccn2)n1 |r|	InChI=1S/C29H37N9O2/c1-36(2)29(40)34-23-6-5-15-38(19-23)25-18-32-26(27(30)39)28(35-25)33-22-10-8-20(9-11-22)21-12-16-37(17-13-21)24-7-3-4-14-31-24/h3-4,7-11,14,18,21,23H,5-6,12-13,15-17,19H2,1-2H3,(H2,30,39)(H,33,35)(H,34,40)	ILNFQODSBZTDGY-UHFFFAOYSA-N	309705	US9656988, Example 174::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-(pyridin-2-yl)piperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309705&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114923	382365766							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594149	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCC2)n1 |r|	InChI=1S/C28H40N8O2/c1-34(2)28(38)32-22-5-4-14-36(18-22)24-17-30-25(26(29)37)27(33-24)31-21-10-8-19(9-11-21)20-12-15-35(16-13-20)23-6-3-7-23/h8-11,17,20,22-23H,3-7,12-16,18H2,1-2H3,(H2,29,37)(H,31,33)(H,32,38)	VFJOIITXTDPWHH-UHFFFAOYSA-N	309706	US9656988, Example 175::(R)-3-(4-(1-cyclobutylpiperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309706	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309706&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114895	382365767							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594154	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCOCC2)n1 |r|	InChI=1S/C29H42N8O3/c1-35(2)29(39)33-23-4-3-13-37(19-23)25-18-31-26(27(30)38)28(34-25)32-22-7-5-20(6-8-22)21-9-14-36(15-10-21)24-11-16-40-17-12-24/h5-8,18,21,23-24H,3-4,9-17,19H2,1-2H3,(H2,30,38)(H,32,34)(H,33,39)	SGOXRXKFGRPCNW-UHFFFAOYSA-N	309707	US9656988, Example 176::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309707	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309707&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114654	382365768							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594159	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CCOCCO)CC2)n1 |r|	InChI=1S/C28H42N8O4/c1-34(2)28(39)32-23-4-3-11-36(19-23)24-18-30-25(26(29)38)27(33-24)31-22-7-5-20(6-8-22)21-9-12-35(13-10-21)14-16-40-17-15-37/h5-8,18,21,23,37H,3-4,9-17,19H2,1-2H3,(H2,29,38)(H,31,33)(H,32,39)	STCSTSSDRJJGME-UHFFFAOYSA-N	309708	US9656988, Example 177::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-(2-(2-hydroxyethoxy)ethyl)piperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309708	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309708&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114492	382365769							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594164	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2COC2)n1 |r|	InChI=1S/C27H38N8O3/c1-33(2)27(37)31-21-4-3-11-35(15-21)23-14-29-24(25(28)36)26(32-23)30-20-7-5-18(6-8-20)19-9-12-34(13-10-19)22-16-38-17-22/h5-8,14,19,21-22H,3-4,9-13,15-17H2,1-2H3,(H2,28,36)(H,30,32)(H,31,37)	JGDSBJDDFRVDDI-UHFFFAOYSA-N	309709	US9656988, Example 178::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-(oxetan-3-yl)piperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309709	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309709&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114902	382365770							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594178	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(F)c(C)n2)n1 |r|	InChI=1S/C19H25FN8O2/c1-11-13(20)6-7-14(23-11)25-18-16(17(21)29)22-9-15(26-18)28-8-4-5-12(10-28)24-19(30)27(2)3/h6-7,9,12H,4-5,8,10H2,1-3H3,(H2,21,29)(H,24,30)(H,23,25,26)	XLPBZHVJISHJRC-UHFFFAOYSA-N	309715	US9656988, Example 184::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(5-fluoro-6-methylpyridin-2-ylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309715	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309715&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115164	382365776							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594183	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccn(C)c(=O)c2)n1 |r|	InChI=1S/C19H26N8O3/c1-25(2)19(30)23-13-5-4-7-27(11-13)14-10-21-16(17(20)29)18(24-14)22-12-6-8-26(3)15(28)9-12/h6,8-10,13H,4-5,7,11H2,1-3H3,(H2,20,29)(H,22,24)(H,23,30)	MREVZXMHOMNGAB-UHFFFAOYSA-N	309716	US9656988, Example 185::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(1-methyl-2-oxo-1,2-dihydropyridin-4-ylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309716	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309716&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115089	382365777							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594200	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(OC3CCCC3)cc2)n1 |r|	InChI=1S/C24H33N7O3/c1-30(2)24(33)28-17-6-5-13-31(15-17)20-14-26-21(22(25)32)23(29-20)27-16-9-11-19(12-10-16)34-18-7-3-4-8-18/h9-12,14,17-18H,3-8,13,15H2,1-2H3,(H2,25,32)(H,27,29)(H,28,33)	PBNBZMPHPCWEFT-UHFFFAOYSA-N	309720	US9656988, Example 189::(R)-3-(4-(cyclopentyloxy)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309720	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309720&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114702	382365781							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594217	CN(C)Cc1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)N(C)C)cc1 |r|	InChI=1S/C22H32N8O2/c1-28(2)13-15-7-9-16(10-8-15)25-21-19(20(23)31)24-12-18(27-21)30-11-5-6-17(14-30)26-22(32)29(3)4/h7-10,12,17H,5-6,11,13-14H2,1-4H3,(H2,23,31)(H,25,27)(H,26,32)	NXORMUJXJIKJBQ-UHFFFAOYSA-N	309724	US9656988, Example 193::(R)-3-(4-((dimethylamino)methyl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309724	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309724&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114871	382365785							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594222	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N(C)C)n1 |r|	InChI=1S/C22H30N8O3/c1-28(2)21(32)14-7-9-15(10-8-14)25-20-18(19(23)31)24-12-17(27-20)30-11-5-6-16(13-30)26-22(33)29(3)4/h7-10,12,16H,5-6,11,13H2,1-4H3,(H2,23,31)(H,25,27)(H,26,33)	LGBGWMQSKQHDJO-UHFFFAOYSA-N	309725	US9656988, Example 194::(R)-3-(4-(dimethylcarbamoyl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309725	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309725&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114904	382365786							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594227	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCCC2)n1 |r|	InChI=1S/C24H32N8O3/c1-30(2)24(35)28-18-6-5-13-32(15-18)19-14-26-20(21(25)33)22(29-19)27-17-9-7-16(8-10-17)23(34)31-11-3-4-12-31/h7-10,14,18H,3-6,11-13,15H2,1-2H3,(H2,25,33)(H,27,29)(H,28,35)	PXFVZCPMWVYICW-UHFFFAOYSA-N	309726	US9656988, Example 195::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(pyrrolidine-1-carbonyl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309726	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309726&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114788	382365787							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594249	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(CN)CC2)n1 |r|	InChI=1S/C23H32N8O2/c1-30(2)22(33)28-17-4-3-11-31(13-17)18-12-26-19(20(25)32)21(29-18)27-16-7-5-15(6-8-16)23(14-24)9-10-23/h5-8,12,17H,3-4,9-11,13-14,24H2,1-2H3,(H2,25,32)(H,27,29)(H,28,33)	YJBUGEZJYGLFJL-UHFFFAOYSA-N	309732	US9656988, Example 201::(R)-3-(4-(1-(aminomethyl)cyclopropyl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309732	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309732&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114466	382365793							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594254	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(CC2)C(=O)N(C)C)n1 |r|	InChI=1S/C25H34N8O3/c1-31(2)23(35)25(11-12-25)16-7-9-17(10-8-16)28-22-20(21(26)34)27-14-19(30-22)33-13-5-6-18(15-33)29-24(36)32(3)4/h7-10,14,18H,5-6,11-13,15H2,1-4H3,(H2,26,34)(H,28,30)(H,29,36)	WWFYYEUUXFNAFM-UHFFFAOYSA-N	309733	US9656988, Example 202::(R)-3-(4-(1-(dimethylcarbamoyl)cyclopropyl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309733	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309733&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114617	382365794							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594262	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(CN)CCCC2)n1 |r|	InChI=1S/C25H36N8O2/c1-32(2)24(35)30-19-6-5-13-33(15-19)20-14-28-21(22(27)34)23(31-20)29-18-9-7-17(8-10-18)25(16-26)11-3-4-12-25/h7-10,14,19H,3-6,11-13,15-16,26H2,1-2H3,(H2,27,34)(H,29,31)(H,30,35)	IBBDJASTLYREBW-UHFFFAOYSA-N	309735	US9656988, Example 204::(R)-3-(4-(1-(aminomethyl)cyclopentyl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309735&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114573	382365796							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594270	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CC2)n1 |r|	InChI=1S/C27H38N8O2/c1-33(2)27(37)31-21-4-3-13-35(17-21)23-16-29-24(25(28)36)26(32-23)30-20-7-5-18(6-8-20)19-11-14-34(15-12-19)22-9-10-22/h5-8,16,19,21-22H,3-4,9-15,17H2,1-2H3,(H2,28,36)(H,30,32)(H,31,37)	UBWVFAXLFXHINF-UHFFFAOYSA-N	309737	US9656988, Example 206::(R)-3-(4-(1-cyclopropylpiperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309737	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309737&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114853	382365798							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594275	CCN1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)N(C)C)cc1 |r|	InChI=1S/C26H38N8O2/c1-4-33-14-11-19(12-15-33)18-7-9-20(10-8-18)29-25-23(24(27)35)28-16-22(31-25)34-13-5-6-21(17-34)30-26(36)32(2)3/h7-10,16,19,21H,4-6,11-15,17H2,1-3H3,(H2,27,35)(H,29,31)(H,30,36)	WARWBXVCRXCYPF-UHFFFAOYSA-N	309738	US9656988, Example 207::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-ethylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309738	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309738&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115238	382365799							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594280	CC(C)N1CCC(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)NC(=O)N(C)C)cc1 |r|	InChI=1S/C27H40N8O2/c1-18(2)34-14-11-20(12-15-34)19-7-9-21(10-8-19)30-26-24(25(28)36)29-16-23(32-26)35-13-5-6-22(17-35)31-27(37)33(3)4/h7-10,16,18,20,22H,5-6,11-15,17H2,1-4H3,(H2,28,36)(H,30,32)(H,31,37)	PJYYQTWKVBLVSS-UHFFFAOYSA-N	309739	US9656988, Example 208::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-isopropylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309739&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114434	382365800							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594285	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCCC2)n1 |r|	InChI=1S/C30H44N8O2/c1-36(2)30(40)34-24-7-6-16-38(20-24)26-19-32-27(28(31)39)29(35-26)33-23-12-10-21(11-13-23)22-14-17-37(18-15-22)25-8-4-3-5-9-25/h10-13,19,22,24-25H,3-9,14-18,20H2,1-2H3,(H2,31,39)(H,33,35)(H,34,40)	QOJBPFSVPCKOOF-UHFFFAOYSA-N	309741	US9656988, Example 210::(R)-3-(4-(1-cyclohexylpiperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309741	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309741&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114490	382365802							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594290	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)c2ccccc2)n1 |r|	InChI=1S/C30H38N8O2/c1-36(2)30(40)34-24-7-6-16-38(20-24)26-19-32-27(28(31)39)29(35-26)33-23-12-10-21(11-13-23)22-14-17-37(18-15-22)25-8-4-3-5-9-25/h3-5,8-13,19,22,24H,6-7,14-18,20H2,1-2H3,(H2,31,39)(H,33,35)(H,34,40)	LLJFREMZKPMZLR-UHFFFAOYSA-N	309742	US9656988, Example 211::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(1-phenylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309742	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309742&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114800	382365803							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594307	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2cnn(c2)C2CC2)n1 |r|	InChI=1S/C19H27N9O2/c1-26(2)19(30)24-12-4-3-7-27(10-12)15-9-21-16(17(20)29)18(25-15)23-13-8-22-28(11-13)14-5-6-14/h8-9,11-12,14H,3-7,10H2,1-2H3,(H2,20,29)(H,23,25)(H,24,30)	TVRPICUSVWZVDJ-UHFFFAOYSA-N	309747	US9656988, Example 216::(R)-3-(1-cyclopropyl-1H-pyrazol-4-ylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309747&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114914	382365808							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594312	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2cnn(c2)C2CCCC2)n1 |r|	InChI=1S/C21H31N9O2/c1-28(2)21(32)26-14-6-5-9-29(12-14)17-11-23-18(19(22)31)20(27-17)25-15-10-24-30(13-15)16-7-3-4-8-16/h10-11,13-14,16H,3-9,12H2,1-2H3,(H2,22,31)(H,25,27)(H,26,32)	RPTKFSUYFFYRIA-UHFFFAOYSA-N	309748	US9656988, Example 217::(R)-3-(1-cyclopentyl-1H-pyrazol-4-ylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309748	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309748&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114664	382365809							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594317	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2cnn(c2)C2CCN(CC2)C(=O)OC(C)(C)C)n1 |r|	InChI=1S/C26H40N10O4/c1-26(2,3)40-25(39)34-11-8-19(9-12-34)36-16-18(13-29-36)30-23-21(22(27)37)28-14-20(32-23)35-10-6-7-17(15-35)31-24(38)33(4)5/h13-14,16-17,19H,6-12,15H2,1-5H3,(H2,27,37)(H,30,32)(H,31,38)	OHKHARJWBBQMQI-UHFFFAOYSA-N	309749	US9656988, Example 218::(R)-3-(1-(1-cyclopentylpiperidin-4-yl)-1H-pyrazol-4-ylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309749	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309749&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115761	382365810							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594322	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2cnn(c2)C2CCN(CC2)C(=O)C2CC2)n1 |r|	InChI=1S/C25H36N10O3/c1-32(2)25(38)30-17-4-3-9-34(14-17)20-13-27-21(22(26)36)23(31-20)29-18-12-28-35(15-18)19-7-10-33(11-8-19)24(37)16-5-6-16/h12-13,15-17,19H,3-11,14H2,1-2H3,(H2,26,36)(H,29,31)(H,30,38)	RDBFWDTVOKUUGE-UHFFFAOYSA-N	309750	US9656988, Example 219::(R)-3-(1-(1-(cyclopropanecarbonyl)piperidin-4-yl)-1H-pyrazol-4-ylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309750&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114892	382365811							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594327	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2cnn(c2)C2CN(C2)C2CCCC2)n1 |r|	InChI=1S/C24H36N10O2/c1-31(2)24(36)29-16-6-5-9-32(12-16)20-11-26-21(22(25)35)23(30-20)28-17-10-27-34(13-17)19-14-33(15-19)18-7-3-4-8-18/h10-11,13,16,18-19H,3-9,12,14-15H2,1-2H3,(H2,25,35)(H,28,30)(H,29,36)	HEJMJEVSIIMKLI-UHFFFAOYSA-N	309751	US9656988, Example 220::(R)-3-(1-(1-cyclopentylazetidin-3-yl)-1H-pyrazol-4-ylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309751	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309751&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114721	382365812							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594332	CN(C)C(=O)N[C@@H]1CCCN(C1)c1cnc(C#N)c(Nc2ccc(cc2)C2(C)CCN(CC2)C(=O)OC(C)(C)C)n1 |r|	InChI=1S/C30H42N8O3/c1-29(2,3)41-28(40)37-16-13-30(4,14-17-37)21-9-11-22(12-10-21)33-26-24(18-31)32-19-25(35-26)38-15-7-8-23(20-38)34-27(39)36(5)6/h9-12,19,23H,7-8,13-17,20H2,1-6H3,(H,33,35)(H,34,39)	UXOKXKVHWDWUBP-UHFFFAOYSA-N	309752	US9656988, Example 221::(R)-5-(3-(3,3-dimethylureido)piperidin-1-yl)-3-(4-(4-methylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide 	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309752	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309752&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115063	382365813							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594367	C[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1)NC(=O)N(C)C |r|	InChI=1S/C30H44N8O2/c1-20-25(34-30(40)36(2)3)9-6-16-38(20)26-19-32-27(28(31)39)29(35-26)33-23-12-10-21(11-13-23)22-14-17-37(18-15-22)24-7-4-5-8-24/h10-13,19-20,22,24-25H,4-9,14-18H2,1-3H3,(H2,31,39)(H,33,35)(H,34,40)	SILNPGWUEYVWOG-UHFFFAOYSA-N	309763	US9656988, Example 232::3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-((2R,3R)-3-(3,3-dimethylureido)-2-methylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309763	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309763&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115306	382365824							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594372	C[C@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1)NC(=O)N(C)C |r|	InChI=1S/C30H44N8O2/c1-20-25(34-30(40)36(2)3)9-6-16-38(20)26-19-32-27(28(31)39)29(35-26)33-23-12-10-21(11-13-23)22-14-17-37(18-15-22)24-7-4-5-8-24/h10-13,19-20,22,24-25H,4-9,14-18H2,1-3H3,(H2,31,39)(H,33,35)(H,34,40)	SILNPGWUEYVWOG-UHFFFAOYSA-N	309764	US9656988, Example 233::3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-((2S,3R)-3-(3,3-dimethylureido)-2-methylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309764&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115168	382365825							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594383	CC[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCC2)n1)NC(=O)N(C)C |r|	InChI=1S/C30H44N8O2/c1-4-25-24(34-30(40)36(2)3)9-6-16-38(25)26-19-32-27(28(31)39)29(35-26)33-22-12-10-20(11-13-22)21-14-17-37(18-15-21)23-7-5-8-23/h10-13,19,21,23-25H,4-9,14-18H2,1-3H3,(H2,31,39)(H,33,35)(H,34,40)	TUTCULUSRKMBLE-UHFFFAOYSA-N	309767	US9656988, Example 236::3-(4-(1-cyclobutylpiperidin-4-yl)phenylamino)-5-((2R,3R)-3-(3,3-dimethylureido)-2-ethylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309767	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309767&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114973	382365828							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594399	C[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(CC2)C#N)n1)NC(=O)N(C)C |r|	InChI=1S/C24H30N8O2/c1-15-18(29-23(34)31(2)3)5-4-12-32(15)19-13-27-20(21(26)33)22(30-19)28-17-8-6-16(7-9-17)24(14-25)10-11-24/h6-9,13,15,18H,4-5,10-12H2,1-3H3,(H2,26,33)(H,28,30)(H,29,34)	FQUIFYYDFZJJPV-UHFFFAOYSA-N	309771	US9656988, Example 240::3-(4-(1-cyanocyclopropyl)phenylamino)-5-((2R,3R)-3-(3,3-dimethylureido)-2-methylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309771	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309771&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115077	382365832							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594404	C[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(CC2)C(N)=O)n1)NC(=O)N(C)C |r|	InChI=1S/C24H32N8O3/c1-14-17(29-23(35)31(2)3)5-4-12-32(14)18-13-27-19(20(25)33)21(30-18)28-16-8-6-15(7-9-16)24(10-11-24)22(26)34/h6-9,13-14,17H,4-5,10-12H2,1-3H3,(H2,25,33)(H2,26,34)(H,28,30)(H,29,35)	JBSYSXFZYWYJEL-UHFFFAOYSA-N	309772	US9656988, Example 241::3-(4-(1-carbamoylcyclopropyl)phenylamino)-5-((2R,3R)-3-(3,3-dimethylureido)-2-methylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309772&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114528	382365833							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594421	C[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(C)CCN(CC2)C(=O)OC(C)(C)C)n1)NC(=O)N(C)C |r|	InChI=1S/C31H46N8O4/c1-20-23(35-28(41)37(6)7)9-8-16-39(20)24-19-33-25(26(32)40)27(36-24)34-22-12-10-21(11-13-22)31(5)14-17-38(18-15-31)29(42)43-30(2,3)4/h10-13,19-20,23H,8-9,14-18H2,1-7H3,(H2,32,40)(H,34,36)(H,35,41)	MFVBCGSKSUGDCV-UHFFFAOYSA-N	309776	US9656988, Example 245::3-(4-(1-cyclopentyl-4-methylpiperidin-4-yl)phenylamino)-5-((2R,3R)-3-(3,3-dimethylureido)-2-methylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309776	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309776&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114465	382365837							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594426	C[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(C)CCN(CC2)C2CCC2)n1)NC(=O)N(C)C |r|	InChI=1S/C30H44N8O2/c1-20-24(34-29(40)36(3)4)9-6-16-38(20)25-19-32-26(27(31)39)28(35-25)33-22-12-10-21(11-13-22)30(2)14-17-37(18-15-30)23-7-5-8-23/h10-13,19-20,23-24H,5-9,14-18H2,1-4H3,(H2,31,39)(H,33,35)(H,34,40)	CDOHBLOZNLWOGC-UHFFFAOYSA-N	309777	US9656988, Example 246::3-(4-(1-cyclobutyl-4-methylpiperidin-4-yl)phenylamino)-5-((2R,3R)-3-(3,3-dimethylureido)-2-methylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309777&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114803	382365838							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594431	C[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(C)CCN(CC2)C2CC2)n1)NC(=O)N(C)C |r|	InChI=1S/C29H42N8O2/c1-19-23(33-28(39)35(3)4)6-5-15-37(19)24-18-31-25(26(30)38)27(34-24)32-21-9-7-20(8-10-21)29(2)13-16-36(17-14-29)22-11-12-22/h7-10,18-19,22-23H,5-6,11-17H2,1-4H3,(H2,30,38)(H,32,34)(H,33,39)	MSLPJPREOGINFQ-UHFFFAOYSA-N	309778	US9656988, Example 247::3-(4-(1-cyclopropyl-4-methylpiperidin-4-yl)phenylamino)-5-((2R,3R)-3-(3,3-dimethylureido)-2-methylpiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309778	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309778&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114825	382365839							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594454	C[C@@H]1[C@@H](CCCN1c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(C)CCN(CC2)C2CCCC2)n1)N1CCN(C)C1=O |r|	InChI=1S/C32H46N8O2/c1-22-26(40-20-19-37(3)31(40)42)9-6-16-39(22)27-21-34-28(29(33)41)30(36-27)35-24-12-10-23(11-13-24)32(2)14-17-38(18-15-32)25-7-4-5-8-25/h10-13,21-22,25-26H,4-9,14-20H2,1-3H3,(H2,33,41)(H,35,36)	QWPAIFRYLCJPRM-UHFFFAOYSA-N	309784	US9656988, Example 253::3-(4-(1-cyclopentyl-4-methylpiperidin-4-yl)phenylamino)-5-((2R,3R)-2-methyl-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 55							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309784&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114986	382365845							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594467	CN1CCN(C1=O)[C@@H]2CCCN(C2)c3cnc(c(n3)Nc4ccc(cc4)C5CCNCC5)C(=O)N	InChI=1S/C25H34N8O2/c1-31-13-14-33(25(31)35)20-3-2-12-32(16-20)21-15-28-22(23(26)34)24(30-21)29-19-6-4-17(5-7-19)18-8-10-27-11-9-18/h4-7,15,18,20,27H,2-3,8-14,16H2,1H3,(H2,26,34)(H,29,30)	JCGXVYWABUYORV-UHFFFAOYSA-N	309787	US9656988, Example 256::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309787&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	WKC	8EJB	118114824	382365848							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594494	CN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C3CC3)n2)C1=O |r|	InChI=1S/C29H40N8O2/c1-29(11-14-35(15-12-29)22-9-10-22)20-5-7-21(8-6-20)32-27-25(26(30)38)31-18-24(33-27)36-13-3-4-23(19-36)37-17-16-34(2)28(37)39/h5-8,18,22-23H,3-4,9-17,19H2,1-2H3,(H2,30,38)(H,32,33)	GRDQZTOKRYJEOD-UHFFFAOYSA-N	309794	US9656988, Example 263::(R)-3-(4-(1-cyclopropyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309794&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114711	382365855							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594499	CC(C)N1CCC(C)(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)N2CCN(C)C2=O)cc1 |r|	InChI=1S/C29H42N8O2/c1-20(2)35-14-11-29(3,12-15-35)21-7-9-22(10-8-21)32-27-25(26(30)38)31-18-24(33-27)36-13-5-6-23(19-36)37-17-16-34(4)28(37)39/h7-10,18,20,23H,5-6,11-17,19H2,1-4H3,(H2,30,38)(H,32,33)	KRBQVVJHGYWGFT-UHFFFAOYSA-N	309795	US9656988, Example 264::(R)-3-(4-(1-isopropyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309795&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114694	382365856							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594504	CN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C3COC3)n2)C1=O |r|	InChI=1S/C29H40N8O3/c1-29(9-12-35(13-10-29)23-18-40-19-23)20-5-7-21(8-6-20)32-27-25(26(30)38)31-16-24(33-27)36-11-3-4-22(17-36)37-15-14-34(2)28(37)39/h5-8,16,22-23H,3-4,9-15,17-19H2,1-2H3,(H2,30,38)(H,32,33)	JAXHLQYMTYAKTB-UHFFFAOYSA-N	309796	US9656988, Example 265::(R)-3-(4-(4-methyl-1-(oxetan-3-yl)piperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309796&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114946	382365857							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594509	CN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C3CCC3)n2)C1=O |r|	InChI=1S/C30H42N8O2/c1-30(12-15-36(16-13-30)23-5-3-6-23)21-8-10-22(11-9-21)33-28-26(27(31)39)32-19-25(34-28)37-14-4-7-24(20-37)38-18-17-35(2)29(38)40/h8-11,19,23-24H,3-7,12-18,20H2,1-2H3,(H2,31,39)(H,33,34)	YOMAOPPNVBYEOX-UHFFFAOYSA-N	309797	US9656988, Example 266::(R)-3-(4-(1-cyclobutyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309797	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309797&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114815	382365858							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594514	CN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C3CCCC3)n2)C1=O |r|	InChI=1S/C31H44N8O2/c1-31(13-16-37(17-14-31)24-6-3-4-7-24)22-9-11-23(12-10-22)34-29-27(28(32)40)33-20-26(35-29)38-15-5-8-25(21-38)39-19-18-36(2)30(39)41/h9-12,20,24-25H,3-8,13-19,21H2,1-2H3,(H2,32,40)(H,34,35)	NDQDOSYMYFLJFT-UHFFFAOYSA-N	309798	US9656988, Example 267::(R)-3-(4-(1-cyclopentyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309798&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114568	382365859							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594519	CN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C=O)n2)C1=O |r|	InChI=1S/C27H36N8O3/c1-27(9-12-33(18-36)13-10-27)19-5-7-20(8-6-19)30-25-23(24(28)37)29-16-22(31-25)34-11-3-4-21(17-34)35-15-14-32(2)26(35)38/h5-8,16,18,21H,3-4,9-15,17H2,1-2H3,(H2,28,37)(H,30,31)	JKTCYIDJXKFDGR-UHFFFAOYSA-N	309799	US9656988, Example 268::(R)-3-(4-(1-formyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309799&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114746	382365860							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594524	CCC(=O)N1CCC(C)(CC1)c1ccc(Nc2nc(cnc2C(N)=O)N2CCC[C@H](C2)N2CCN(C)C2=O)cc1 |r|	InChI=1S/C29H40N8O3/c1-4-24(38)35-14-11-29(2,12-15-35)20-7-9-21(10-8-20)32-27-25(26(30)39)31-18-23(33-27)36-13-5-6-22(19-36)37-17-16-34(3)28(37)40/h7-10,18,22H,4-6,11-17,19H2,1-3H3,(H2,30,39)(H,32,33)	VQCCZYPJUKJUCY-UHFFFAOYSA-N	309800	US9656988, Example 269::(R)-3-(4-(4-methyl-1-propionylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309800&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115021	382365861							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594529	CN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C(=O)C3CC3)n2)C1=O |r|	InChI=1S/C30H40N8O3/c1-30(11-14-36(15-12-30)28(40)20-5-6-20)21-7-9-22(10-8-21)33-27-25(26(31)39)32-18-24(34-27)37-13-3-4-23(19-37)38-17-16-35(2)29(38)41/h7-10,18,20,23H,3-6,11-17,19H2,1-2H3,(H2,31,39)(H,33,34)	ZVTYOOQKQKVLKZ-UHFFFAOYSA-N	309801	US9656988, Example 270::(R)-3-(4-(1-(cyclopropanecarbonyl)-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309801&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114867	382365862							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594550	CCN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3CCN(CC3)C3CCCC3)n2)C1=O |r|	InChI=1S/C31H44N8O2/c1-2-36-18-19-39(31(36)41)26-8-5-15-38(21-26)27-20-33-28(29(32)40)30(35-27)34-24-11-9-22(10-12-24)23-13-16-37(17-14-23)25-6-3-4-7-25/h9-12,20,23,25-26H,2-8,13-19,21H2,1H3,(H2,32,40)(H,34,35)	QMXSHAJJEPUPLY-UHFFFAOYSA-N	309806	US9656988, Example 275::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(3-ethyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309806&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114586	382365867							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594555	CCN1CCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C3CC3)n2)C1=O |r|	InChI=1S/C30H42N8O2/c1-3-35-17-18-38(29(35)40)24-5-4-14-37(20-24)25-19-32-26(27(31)39)28(34-25)33-22-8-6-21(7-9-22)30(2)12-15-36(16-13-30)23-10-11-23/h6-9,19,23-24H,3-5,10-18,20H2,1-2H3,(H2,31,39)(H,33,34)	PZUMBRCJMFLXDR-UHFFFAOYSA-N	309807	US9656988, Example 276::(R)-3-(4-(1-cyclopropyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-ethyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309807&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114992	382365868							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594576	C[C@@H]1[C@@H](CCCN1c1cnc(C#N)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1)N1CCCN(C)C1=O |r|	InChI=1S/C32H44N8O/c1-23-29(40-18-6-16-37(2)32(40)41)9-5-17-39(23)30-22-34-28(21-33)31(36-30)35-26-12-10-24(11-13-26)25-14-19-38(20-15-25)27-7-3-4-8-27/h10-13,22-23,25,27,29H,3-9,14-20H2,1-2H3,(H,35,36)	RBBBWMGEVIGGPY-UHFFFAOYSA-N	309812	US9656988, Example 281::3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-((2R,3R)-2-methyl-3-(3-methyl-2-oxotetrahydropyrimidin-1(2H)-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309812&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114630	382365873							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594585	CN1CCCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C3CCCC3)n2)C1=O |r|	InChI=1S/C32H46N8O2/c1-32(14-19-38(20-15-32)25-7-3-4-8-25)23-10-12-24(13-11-23)35-30-28(29(33)41)34-21-27(36-30)39-17-5-9-26(22-39)40-18-6-16-37(2)31(40)42/h10-13,21,25-26H,3-9,14-20,22H2,1-2H3,(H2,33,41)(H,35,36)	YSAFNKIWUWRWQG-UHFFFAOYSA-N	309814	US9656988, Example 283::(R)-3-(4-(1-cyclopentyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxotetrahydropyrimidin-1(2H)-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309814&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114468	382365875							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594590	CN1CCCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3CCN(CC3)C3CC3)n2)C1=O |r|	InChI=1S/C29H40N8O2/c1-34-13-3-15-37(29(34)39)24-4-2-14-36(19-24)25-18-31-26(27(30)38)28(33-25)32-22-7-5-20(6-8-22)21-11-16-35(17-12-21)23-9-10-23/h5-8,18,21,23-24H,2-4,9-17,19H2,1H3,(H2,30,38)(H,32,33)	OLAAZMUTOKWQQN-UHFFFAOYSA-N	309815	US9656988, Example 284::(R)-3-(4-(1-cyclopropylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxotetrahydropyrimidin-1(2H)-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309815&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114571	382365876							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594595	CN1CCCN([C@@H]2CCCN(C2)c2cnc(C(N)=O)c(Nc3ccc(cc3)C3(C)CCN(CC3)C3CC3)n2)C1=O |r|	InChI=1S/C30H42N8O2/c1-30(12-17-36(18-13-30)23-10-11-23)21-6-8-22(9-7-21)33-28-26(27(31)39)32-19-25(34-28)37-15-3-5-24(20-37)38-16-4-14-35(2)29(38)40/h6-9,19,23-24H,3-5,10-18,20H2,1-2H3,(H2,31,39)(H,33,34)	UDOPWNZLOSLIPA-UHFFFAOYSA-N	309816	US9656988, Example 285::(R)-3-(4-(1-cyclopropyl-4-methylpiperidin-4-yl)phenylamino)-5-(3-(3-methyl-2-oxotetrahydropyrimidin-1(2H)-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309816&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114773	382365877							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594612	CN(C)C(=O)N1CCC[C@@H]2[C@H]1CCCN2c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1 |r|	InChI=1S/C32H46N8O2/c1-37(2)32(42)40-18-6-9-26-27(40)10-5-17-39(26)28-21-34-29(30(33)41)31(36-28)35-24-13-11-22(12-14-24)23-15-19-38(20-16-23)25-7-3-4-8-25/h11-14,21,23,25-27H,3-10,15-20H2,1-2H3,(H2,33,41)(H,35,36)	SRSSGGWPOCYTRY-UHFFFAOYSA-N	309820	US9656988, Example 289::(4aR,8aR)-5-(5-carbamoyl-6-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)pyrazin-2-yl)-N,N-dimethyloctahydro-1,5-naphthyridine-1(2H)-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309820&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115015	382365881							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594633	N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1 |r|	InChI=1S/C26H37N7O/c27-20-4-3-13-33(17-20)23-16-29-24(25(28)34)26(31-23)30-21-9-7-18(8-10-21)19-11-14-32(15-12-19)22-5-1-2-6-22/h7-10,16,19-20,22H,1-6,11-15,17,27H2,(H2,28,34)(H,30,31)	YILVNDUVPVMTNQ-UHFFFAOYSA-N	309825	US9656988, Example 294::(R)-5-(3-aminopiperidin-1-yl)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309825&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114439	382365886							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594638	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)NC=O |r|	InChI=1S/C27H37N7O2/c28-26(36)25-27(32-24(16-29-25)34-13-3-4-22(17-34)30-18-35)31-21-9-7-19(8-10-21)20-11-14-33(15-12-20)23-5-1-2-6-23/h7-10,16,18,20,22-23H,1-6,11-15,17H2,(H2,28,36)(H,30,35)(H,31,32)	OKHDBWUWJJHQTM-UHFFFAOYSA-N	309826	US9656988, Example 295::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-formamidopiperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309826&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115372	382365887					C06049		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594649	CCOC(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1 |r|	InChI=1S/C29H41N7O3/c1-2-39-29(38)33-23-6-5-15-36(19-23)25-18-31-26(27(30)37)28(34-25)32-22-11-9-20(10-12-22)21-13-16-35(17-14-21)24-7-3-4-8-24/h9-12,18,21,23-24H,2-8,13-17,19H2,1H3,(H2,30,37)(H,32,34)(H,33,38)	FGVHSAZTCGXYQT-UHFFFAOYSA-N	309829	US9656988, Example 298::(R)-ethyl 1-(5-carbamoyl-6-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)pyrazin-2-yl)piperidin-3-ylcarbamate	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309829&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115733	382365890							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594654	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)NC(=O)C1CC1 |r|	InChI=1S/C30H41N7O2/c31-28(38)27-29(35-26(18-32-27)37-15-3-4-24(19-37)34-30(39)22-7-8-22)33-23-11-9-20(10-12-23)21-13-16-36(17-14-21)25-5-1-2-6-25/h9-12,18,21-22,24-25H,1-8,13-17,19H2,(H2,31,38)(H,33,35)(H,34,39)	AYPQJCUSHCNNTD-UHFFFAOYSA-N	309830	US9656988, Example 299::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(cyclopropanecarboxamido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309830&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115040	382365891							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594659	CS(=O)(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1 |r|	InChI=1S/C27H39N7O3S/c1-38(36,37)32-22-5-4-14-34(18-22)24-17-29-25(26(28)35)27(31-24)30-21-10-8-19(9-11-21)20-12-15-33(16-13-20)23-6-2-3-7-23/h8-11,17,20,22-23,32H,2-7,12-16,18H2,1H3,(H2,28,35)(H,30,31)	HPHASEBRPJNUNL-UHFFFAOYSA-N	309831	US9656988, Example 300::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(methylsulfonamido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309831&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114931	382365892							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594667	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)NC(=O)c1ccccc1 |r|	InChI=1S/C33H41N7O2/c34-31(41)30-32(36-26-14-12-23(13-15-26)24-16-19-39(20-17-24)28-10-4-5-11-28)38-29(21-35-30)40-18-6-9-27(22-40)37-33(42)25-7-2-1-3-8-25/h1-3,7-8,12-15,21,24,27-28H,4-6,9-11,16-20,22H2,(H2,34,41)(H,36,38)(H,37,42)	LLUKGAWEUSVECT-UHFFFAOYSA-N	309834	US9656988, Example 303::(R)-5-(3-benzamidopiperidin-1-yl)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309834&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115331	382365895							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594676	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)NC(=O)c1cncc(F)c1 |r|	InChI=1S/C32H39FN8O2/c33-24-16-23(17-35-18-24)32(43)38-26-4-3-13-41(20-26)28-19-36-29(30(34)42)31(39-28)37-25-9-7-21(8-10-25)22-11-14-40(15-12-22)27-5-1-2-6-27/h7-10,16-19,22,26-27H,1-6,11-15,20H2,(H2,34,42)(H,37,39)(H,38,43)	CXHZBOWLLILCRJ-UHFFFAOYSA-N	309836	US9656988, Example 305::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(5-fluoronicotinamido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309836&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114674	382365897							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594681	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)NC(=O)CCCBr |r|	InChI=1S/C30H42BrN7O2/c31-15-3-8-27(39)34-24-5-4-16-38(20-24)26-19-33-28(29(32)40)30(36-26)35-23-11-9-21(10-12-23)22-13-17-37(18-14-22)25-6-1-2-7-25/h9-12,19,22,24-25H,1-8,13-18,20H2,(H2,32,40)(H,34,39)(H,35,36)	MRLOXOXQQPFOTC-UHFFFAOYSA-N	309837	US9656988, Example 306::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(2-oxopyrrolidin-1-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309837&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115754	382365898							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594686	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)N1Cc2ccccc2C1=O |r|	InChI=1S/C34H41N7O2/c35-32(42)31-33(37-26-13-11-23(12-14-26)24-15-18-39(19-16-24)27-7-2-3-8-27)38-30(20-36-31)40-17-5-9-28(22-40)41-21-25-6-1-4-10-29(25)34(41)43/h1,4,6,10-14,20,24,27-28H,2-3,5,7-9,15-19,21-22H2,(H2,35,42)(H,37,38)	UPGMKOOJQCKFAP-UHFFFAOYSA-N	309838	US9656988, Example 307::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(1-oxoisoindolin-2-yl)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309838&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115082	382365899							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594734	CN(C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(F)cc2)n1)c1cc(Cl)cc(c1)C(F)(F)F |r|	InChI=1S/C25H24ClF4N7O2/c1-36(19-10-14(25(28,29)30)9-15(26)11-19)24(39)34-18-3-2-8-37(13-18)20-12-32-21(22(31)38)23(35-20)33-17-6-4-16(27)5-7-17/h4-7,9-12,18H,2-3,8,13H2,1H3,(H2,31,38)(H,33,35)(H,34,39)	DZTBHDMRYDNZDX-UHFFFAOYSA-N	309853	US9656988, Example 322::(R)-5-(3-(3-(3-chloro-5-(trifluoromethyl)phenyl)-3-methylureido)piperidin-1-yl)-3-(4-fluorophenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309853&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115091	382365914							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594739	CN(C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(CC2)C#N)n1)c1cc(Cl)cc(c1)C(F)(F)F |r|	InChI=1S/C29H28ClF3N8O2/c1-40(22-12-18(29(31,32)33)11-19(30)13-22)27(43)38-21-3-2-10-41(15-21)23-14-36-24(25(35)42)26(39-23)37-20-6-4-17(5-7-20)28(16-34)8-9-28/h4-7,11-14,21H,2-3,8-10,15H2,1H3,(H2,35,42)(H,37,39)(H,38,43)	RUXZDNLBAGPFPQ-UHFFFAOYSA-N	309854	US9656988, Example 323::(R)-5-(3-(3-(3-chloro-5-(trifluoromethyl)phenyl)-3-methylureido)piperidin-1-yl)-3-(4-(1-cyanocyclopropyl)phenylamino)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309854	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309854&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114910	382365915							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594744	CN(C(=O)N[C@@H]1CCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2(CC2)C(N)=O)n1)c1cc(Cl)cc(c1)C(F)(F)F |r|	InChI=1S/C29H30ClF3N8O3/c1-40(21-12-17(29(31,32)33)11-18(30)13-21)27(44)38-20-3-2-10-41(15-20)22-14-36-23(24(34)42)25(39-22)37-19-6-4-16(5-7-19)28(8-9-28)26(35)43/h4-7,11-14,20H,2-3,8-10,15H2,1H3,(H2,34,42)(H2,35,43)(H,37,39)(H,38,44)	WHGCLCOZWIDXLS-UHFFFAOYSA-N	309855	US9656988, Example 324::(R)-3-(4-(1-carbamoylcyclopropyl)phenylamino)-5-(3-(3-(3-chloro-5-(trifluoromethyl)phenyl)-3-methylureido)piperidin-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		>10000							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309855	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309855&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114507	382365916							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594755	CN(C)C(=O)N[C@@H]1CCCCN(C1)c1cnc(C(N)=O)c(Nc2ccc(cc2)C2CCN(CC2)C2CCCC2)n1 |r|	InChI=1S/C30H44N8O2/c1-36(2)30(40)34-24-7-5-6-16-38(20-24)26-19-32-27(28(31)39)29(35-26)33-23-12-10-21(11-13-23)22-14-17-37(18-15-22)25-8-3-4-9-25/h10-13,19,22,24-25H,3-9,14-18,20H2,1-2H3,(H2,31,39)(H,33,35)(H,34,40)	NQPDYSIWILAKNW-UHFFFAOYSA-N	309858	US9656988, Example 327::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(3,3-dimethylureido)azepan-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309858	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309858&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114936	382365919							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594760	NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCCC[C@H](C1)NC(=O)C1CC1 |r|	InChI=1S/C31H43N7O2/c32-29(39)28-30(36-27(19-33-28)38-16-4-3-5-25(20-38)35-31(40)23-8-9-23)34-24-12-10-21(11-13-24)22-14-17-37(18-15-22)26-6-1-2-7-26/h10-13,19,22-23,25-26H,1-9,14-18,20H2,(H2,32,39)(H,34,36)(H,35,40)	GBZJWIWJKOKRGY-UHFFFAOYSA-N	309859	US9656988, Example 328::(R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(cyclopropanecarboxamido)azepan-1-yl)pyrazine-2-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309859	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309859&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114963	382365920							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594772	NC(=O)c1nnc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)NC(=O)N1CCCCC1 |r|	InChI=1S/C31H45N9O2/c32-28(41)27-29(33-24-12-10-22(11-13-24)23-14-19-38(20-15-23)26-8-2-3-9-26)35-30(37-36-27)40-18-6-7-25(21-40)34-31(42)39-16-4-1-5-17-39/h10-13,23,25-26H,1-9,14-21H2,(H2,32,41)(H,34,42)(H,33,35,37)	BAFUFCIHPPFMHP-UHFFFAOYSA-N	309867	US9656988, Example 336::(R)-5-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-3-(3-(piperidine-1-carboxamido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 550							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309867&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114405	382365928							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594776	NC(=O)c1nnc(nc1Nc1ccc(cc1)C1CCN(CC1)C=O)N1CCC[C@H](C1)NC(=O)N1CCCCC1 |r|	InChI=1S/C27H37N9O3/c28-24(38)23-25(29-21-8-6-19(7-9-21)20-10-15-34(18-37)16-11-20)31-26(33-32-23)36-14-4-5-22(17-36)30-27(39)35-12-2-1-3-13-35/h6-9,18,20,22H,1-5,10-17H2,(H2,28,38)(H,30,39)(H,29,31,33)	QQCIEUDKVLVHCV-UHFFFAOYSA-N	309868	US9656988, Example 337::(R)-5-(4-(1-formylpiperidin-4-yl)phenylamino)-3-(3-(piperidine-1-carboxamido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309868&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114544	382365929							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594780	CC(=O)N1CCC(CC1)c1ccc(Nc2nc(nnc2C(N)=O)N2CCC[C@H](C2)NC(=O)N2CCCCC2)cc1 |r|	InChI=1S/C28H39N9O3/c1-19(38)35-16-11-21(12-17-35)20-7-9-22(10-8-20)30-26-24(25(29)39)33-34-27(32-26)37-15-5-6-23(18-37)31-28(40)36-13-3-2-4-14-36/h7-10,21,23H,2-6,11-18H2,1H3,(H2,29,39)(H,31,40)(H,30,32,34)	PTGDURRRTYAKSP-UHFFFAOYSA-N	309869	US9656988, Example 338::(R)-5-(4-(1-acetylpiperidin-4-yl)phenylamino)-3-(3-(piperidine-1-carboxamido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309869&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114958	382365930							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594784	CCC(=O)N1CCC(CC1)c1ccc(Nc2nc(nnc2C(N)=O)N2CCC[C@H](C2)NC(=O)N2CCCCC2)cc1 |r|	InChI=1S/C29H41N9O3/c1-2-24(39)36-17-12-21(13-18-36)20-8-10-22(11-9-20)31-27-25(26(30)40)34-35-28(33-27)38-16-6-7-23(19-38)32-29(41)37-14-4-3-5-15-37/h8-11,21,23H,2-7,12-19H2,1H3,(H2,30,40)(H,32,41)(H,31,33,35)	IGFDSAPXMROBGZ-UHFFFAOYSA-N	309870	US9656988, Example 339::(R)-3-(3-(piperidine-1-carboxamido)piperidin-1-yl)-5-(4-(1-propionylpiperidin-4-yl)phenylamino)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309870&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114590	382365931							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594788	NC(=O)c1nnc(nc1Nc1ccc(cc1)C1CCN(CC1)C(=O)CC#N)N1CCC[C@H](C1)NC(=O)N1CCCCC1 |r|	InChI=1S/C29H38N10O3/c30-13-10-24(40)37-17-11-21(12-18-37)20-6-8-22(9-7-20)32-27-25(26(31)41)35-36-28(34-27)39-16-4-5-23(19-39)33-29(42)38-14-2-1-3-15-38/h6-9,21,23H,1-5,10-12,14-19H2,(H2,31,41)(H,33,42)(H,32,34,36)	SRXOUOLDYVNBOW-UHFFFAOYSA-N	309872	US9656988, Example 341::(R)-5-(4-(1-(2-cyanoacetyl)piperidin-4-yl)phenylamino)-3-(3-(piperidine-1-carboxamido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309872	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309872&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114844	382365933							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594792	CCOc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)C(=N)N(C)C)n1 |r|	InChI=1S/C27H33N9O3/c1-4-39-21-13-9-18(10-14-21)26(38)31-20-6-5-15-36(16-20)27-32-25(22(24(29)37)33-34-27)30-19-11-7-17(8-12-19)23(28)35(2)3/h7-14,20,28H,4-6,15-16H2,1-3H3,(H2,29,37)(H,31,38)(H,30,32,34)	ZNGUGRPPJGPZKE-UHFFFAOYSA-N	309873	US9656988, Example 342::(R)-5-(4-(N,N-dimethylcarbamimidoyl)phenylamino)-3-(3-(4-ethoxybenzamido)piperidin-1-yl)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309873&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114397	382365934							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594796	CCOc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)C(=N)N2CCCC2)n1 |r|	InChI=1S/C29H35N9O3/c1-2-41-23-13-9-20(10-14-23)28(40)33-22-6-5-17-38(18-22)29-34-27(24(26(31)39)35-36-29)32-21-11-7-19(8-12-21)25(30)37-15-3-4-16-37/h7-14,22,30H,2-6,15-18H2,1H3,(H2,31,39)(H,33,40)(H,32,34,36)	QMPCZRYAQUSGAU-UHFFFAOYSA-N	309874	US9656988, Example 343::(R)-3-(3-(4-ethoxybenzamido)piperidin-1-yl)-5-(4-(imino(pyrrolidin-1-yl)methyl)phenylamino)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309874	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309874&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114696	382365935							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594800	CCOc1ccc(cc1)C(=O)N[C@@H]1CCCN(C1)c1nnc(C(N)=O)c(Nc2ccc(cc2)C2=NCCN2C)n1 |r,t:36|	InChI=1S/C28H33N9O3/c1-3-40-22-12-8-19(9-13-22)27(39)32-21-5-4-15-37(17-21)28-33-25(23(24(29)38)34-35-28)31-20-10-6-18(7-11-20)26-30-14-16-36(26)2/h6-13,21H,3-5,14-17H2,1-2H3,(H2,29,38)(H,32,39)(H,31,33,35)	ZXTBMPGMUNFAIQ-UHFFFAOYSA-N	309875	US9656988, Example 344::(R)-3-(3-(4-ethoxybenzamido)piperidin-1-yl)-5-(4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenylamino)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309875&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118115036	382365936							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
594805	CC#CC(=O)N1CC[C@H](C1)Nc1nnc(C(N)=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1 |r|	InChI=1S/C23H26N8O4/c1-2-3-18(32)31-9-8-17(14-31)26-23-27-21(19(20(24)33)28-29-23)25-16-6-4-15(5-7-16)22(34)30-10-12-35-13-11-30/h4-7,17H,8-14H2,1H3,(H2,24,33)(H2,25,26,27,29)	PGOUMVSFSMZEQT-UHFFFAOYSA-N	309876	US9656988, Example 345::US9656988, Example 345A::(R)-3-(1-but-2-ynoylpyrrolidin-3-ylamino)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide	Epidermal growth factor receptor	Human		 5500							US Patent		10.7270/Q25Q4Z49		aid1796250	US9656988	Chen, W; Jia, ZJ; Thomas, WD	5/23/2017	4/9/2019	Pharmacyclics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=309876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=309876&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118114692	382365937							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
605145	CN1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Oc4cccc(c4)NC(=O)C=C)Cl	InChI=1S/C25H27ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,33)(H,27,29,30)	ITTRLTNMFYIYPA-UHFFFAOYSA-N	50383274	CHEMBL1229592::US9670213, WZ4002::US10167264, WZ4002	Epidermal growth factor receptor	Human			 46.0						US Patent		10.7270/Q2CZ397P		aid1796430	US10167264	Zhang, D	1/1/2019	4/24/2019	Jiangsu Medolution	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383274	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383274&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0UN	7ZYN,5X2K,3IKA	44607530	160862357	61400	CHEMBL1229592					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
605147	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)cc1	InChI=1S/C26H26F3N7O2/c1-3-23(38)31-19-5-4-6-20(15-19)32-24-22(26(27,28)29)16-30-25(34-24)33-18-7-9-21(10-8-18)36-13-11-35(12-14-36)17(2)37/h3-10,15-16H,1,11-14H2,2H3,(H,31,38)(H2,30,32,33,34)	DZJSZQXSTKDPSJ-UHFFFAOYSA-N	313221	N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl] prop-2-enamide ::US10167264, Compound 8	Epidermal growth factor receptor	Human			 84.0						US Patent		10.7270/Q2CZ397P		aid1796430	US10167264	Zhang, D	1/1/2019	4/24/2019	Jiangsu Medolution	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313221	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313221&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118303619	383540131							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
605149	CCN1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)cc1	InChI=1S/C26H28F3N7O/c1-3-23(37)31-19-6-5-7-20(16-19)32-24-22(26(27,28)29)17-30-25(34-24)33-18-8-10-21(11-9-18)36-14-12-35(4-2)13-15-36/h3,5-11,16-17H,1,4,12-15H2,2H3,(H,31,37)(H2,30,32,33,34)	MQUIYZHBFOBMJN-UHFFFAOYSA-N	313222	N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide ::US10167264, Compound 9	Epidermal growth factor receptor	Human			 15.0						US Patent		10.7270/Q2CZ397P		aid1796430	US10167264	Zhang, D	1/1/2019	4/24/2019	Jiangsu Medolution	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313222	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313222&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91827401	383540132							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623141	CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C28H28N6O/c1-3-26(35)30-23-8-4-6-20(18-23)25-9-5-7-21-19-29-28(32-27(21)25)31-22-10-12-24(13-11-22)34-16-14-33(2)15-17-34/h3-13,18-19H,1,14-17H2,2H3,(H,30,35)(H,29,31,32)	JRQMQSHULVFCLG-UHFFFAOYSA-N	318868	US10172868, Compound C021::N-(3-(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C021::US11304957, Compound C021	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318868&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908903	384222157							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623148	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C29H28N6O2/c1-3-27(37)31-24-8-4-6-21(18-24)26-9-5-7-22-19-30-29(33-28(22)26)32-23-10-12-25(13-11-23)35-16-14-34(15-17-35)20(2)36/h3-13,18-19H,1,14-17H2,2H3,(H,31,37)(H,30,32,33)	XIKPVMSKIDGJAK-UHFFFAOYSA-N	318869	US10172868, Compound C032::N-(3-(2-((4-(4-acetylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C032::US11304957, Compound C032	Epidermal growth factor receptor	Human		 300							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318869&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908649	384222158							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623150	CN1CCN(CC1)c1ccc(Nc2ncc3ccc(C)c(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C29H30N6O/c1-4-26(36)31-24-7-5-6-21(18-24)27-20(2)8-9-22-19-30-29(33-28(22)27)32-23-10-12-25(13-11-23)35-16-14-34(3)15-17-35/h4-13,18-19H,1,14-17H2,2-3H3,(H,31,36)(H,30,32,33)	XRBWJTJUCPVZMO-UHFFFAOYSA-N	318870	US10172868, Compound C034::N-(3-(7-methyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C034::US11304957, Compound C034	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318870&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909529	384222159							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623152	CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cncc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C27H27N7O/c1-3-25(35)30-22-15-20(16-28-18-22)24-6-4-5-19-17-29-27(32-26(19)24)31-21-7-9-23(10-8-21)34-13-11-33(2)12-14-34/h3-10,15-18H,1,11-14H2,2H3,(H,30,35)(H,29,31,32)	LDYYASFARAYPHC-UHFFFAOYSA-N	318871	US10172868, Compound C040::N-(5-(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)pyridin-3-yl)acrylamide::US10653701, Compound C040::US11304957, Compound C040	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318871	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318871&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909179	384222160							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623154	CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cn1	InChI=1S/C27H27N7O/c1-3-25(35)30-21-8-4-6-19(16-21)23-9-5-7-20-17-29-27(32-26(20)23)31-22-10-11-24(28-18-22)34-14-12-33(2)13-15-34/h3-11,16-18H,1,12-15H2,2H3,(H,30,35)(H,29,31,32)	DWWBJIZUAPUUFO-UHFFFAOYSA-N	318872	US10172868, Compound C041::N-(3-(2-((6-(4-methylpiperazin-1-yl)pyridin-3-yl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C041::US11304957, Compound C041	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318872	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318872&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908828	384222161							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623160	CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)c(F)c1	InChI=1S/C28H27FN6O/c1-3-26(36)31-21-8-4-6-19(16-21)23-9-5-7-20-18-30-28(33-27(20)23)32-25-11-10-22(17-24(25)29)35-14-12-34(2)13-15-35/h3-11,16-18H,1,12-15H2,2H3,(H,31,36)(H,30,32,33)	FUUDLGLDEWHVQN-UHFFFAOYSA-N	318873	US10172868, Compound C044::N-(3-(2-((2-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C044::US11304957, Compound C044	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318873&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909051	384222162							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623167	CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4F)c3n2)cn1	InChI=1S/C27H26FN7O/c1-3-24(36)32-22-9-5-7-20(25(22)28)21-8-4-6-18-16-30-27(33-26(18)21)31-19-10-11-23(29-17-19)35-14-12-34(2)13-15-35/h3-11,16-17H,1,12-15H2,2H3,(H,32,36)(H,30,31,33)	UKMFJDYDNMGZMP-UHFFFAOYSA-N	318875	US10172868, Compound C048::N-(2-fluoro-3-(2-((6-(4-methylpiperazin-1-yl)pyridin-3-yl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C048::US11304957, Compound C048	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318875&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909593	384222164							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623172	OCCN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C29H30N6O2/c1-2-27(37)31-24-7-3-5-21(19-24)26-8-4-6-22-20-30-29(33-28(22)26)32-23-9-11-25(12-10-23)35-15-13-34(14-16-35)17-18-36/h2-12,19-20,36H,1,13-18H2,(H,31,37)(H,30,32,33)	LCMKXMHETMWWTO-UHFFFAOYSA-N	318879	US10172868, Compound C059::N-(3-(2-((4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C059::US11304957, Compound C059	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318879	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318879&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908807	384222168							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623188	CN1CCC(Oc2ccc(Nc3ncc4cccc(-c5cccc(NC(=O)C=C)c5)c4n3)cc2)C(F)C1	InChI=1S/C29H28FN5O2/c1-3-27(36)32-22-8-4-6-19(16-22)24-9-5-7-20-17-31-29(34-28(20)24)33-21-10-12-23(13-11-21)37-26-14-15-35(2)18-25(26)30/h3-13,16-17,25-26H,1,14-15,18H2,2H3,(H,32,36)(H,31,33,34)	FQCLNUWLGGCBFN-UHFFFAOYSA-N	318889	US10172868, Compound C079::N-(3-(2-((4-((3-fluoro-1-methylpiperidin-4-yl)oxy)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C079::US11304957, Compound C079	Epidermal growth factor receptor	Human		 300							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318889	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318889&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908708	384222178							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623193	CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1C(N)=O	InChI=1S/C29H29N7O2/c1-3-26(37)32-21-8-4-6-19(16-21)23-9-5-7-20-18-31-29(34-27(20)23)33-22-10-11-25(24(17-22)28(30)38)36-14-12-35(2)13-15-36/h3-11,16-18H,1,12-15H2,2H3,(H2,30,38)(H,32,37)(H,31,33,34)	AFQLFRQVPNTTHV-UHFFFAOYSA-N	318892	US10172868, Compound C085::5-((8-(3-acrylamidophenyl)quinazolin-2-yl)amino)-2-(4-methylpiperazin-1-yl)benzamide::US10653701, Compound C085::US11304957, Compound C085	Epidermal growth factor receptor	Human		 300							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318892	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318892&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909050	384222181							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623198	OCCN1CC(C1)Nc1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C28H28N6O2/c1-2-26(36)31-23-7-3-5-19(15-23)25-8-4-6-20-16-29-28(33-27(20)25)32-22-11-9-21(10-12-22)30-24-17-34(18-24)13-14-35/h2-12,15-16,24,30,35H,1,13-14,17-18H2,(H,31,36)(H,29,32,33)	ZZSYZBGNOCCFDT-UHFFFAOYSA-N	318895	US10172868, Compound C099::N-(3-(2-((4-((1-(2-hydroxyethyl)azetidin-3-yl)amino)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C099::US11304957, Compound C099	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318895	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318895&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908671	384222184							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623202	CN1CCC(Nc2ccc(Nc3ncc4cccc(-c5cccc(NC(=O)C=C)c5)c4n3)cc2)C(F)C1	InChI=1S/C29H29FN6O/c1-3-27(37)33-23-8-4-6-19(16-23)24-9-5-7-20-17-31-29(35-28(20)24)34-22-12-10-21(11-13-22)32-26-14-15-36(2)18-25(26)30/h3-13,16-17,25-26,32H,1,14-15,18H2,2H3,(H,33,37)(H,31,34,35)	SQVLVNUAXMOLMM-UHFFFAOYSA-N	318897	US10172868, Compound C105::N-(3-(2-((4-((3-fluoro-1-methylpiperidin-4-yl)amino)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C105	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318897	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318897&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908919	384222186							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623205	CN1CCN(C(=O)C1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C28H26N6O2/c1-3-25(35)30-22-8-4-6-19(16-22)24-9-5-7-20-17-29-28(32-27(20)24)31-21-10-12-23(13-11-21)34-15-14-33(2)18-26(34)36/h3-13,16-17H,1,14-15,18H2,2H3,(H,30,35)(H,29,31,32)	MYSKGDZXCSZEAB-UHFFFAOYSA-N	318898	US10172868, Compound C106::N-(3-(2-((4-(4-methyl-2-oxopiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C106::US11304957, Compound C106	Epidermal growth factor receptor	Human		>500							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318898	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318898&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909398	384222187							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623208	COCCOc1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C26H24N4O3/c1-3-24(31)28-21-8-4-6-18(16-21)23-9-5-7-19-17-27-26(30-25(19)23)29-20-10-12-22(13-11-20)33-15-14-32-2/h3-13,16-17H,1,14-15H2,2H3,(H,28,31)(H,27,29,30)	RQECVRMOFHDYBX-UHFFFAOYSA-N	318899	US10172868, Compound C107::N-(3-(2-((4-(2-methoxyethoxy)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C107::US11304957, Compound C107	Epidermal growth factor receptor	Human		>500							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318899	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318899&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90659749	384222188							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623211	OCCOc1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1	InChI=1S/C25H22N4O3/c1-2-23(31)27-20-7-3-5-17(15-20)22-8-4-6-18-16-26-25(29-24(18)22)28-19-9-11-21(12-10-19)32-14-13-30/h2-12,15-16,30H,1,13-14H2,(H,27,31)(H,26,28,29)	FEFINBMHJQGFOG-UHFFFAOYSA-N	318900	US10172868, Compound C108::N-(3-(2-((4-(2-hydroxyethoxy)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C108::US11304957, Compound C108	Epidermal growth factor receptor	Human		 300							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318900	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318900&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909412	384222189							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623228	OCCN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)c(F)c1	InChI=1S/C29H29FN6O2/c1-2-27(38)32-22-7-3-5-20(17-22)24-8-4-6-21-19-31-29(34-28(21)24)33-26-10-9-23(18-25(26)30)36-13-11-35(12-14-36)15-16-37/h2-10,17-19,37H,1,11-16H2,(H,32,38)(H,31,33,34)	LOHGOSYFXUKKCF-UHFFFAOYSA-N	318915	US10172868, Compound C147::N-(3-(2-((2-fluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C147::US11304957, Compound C147	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318915	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318915&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117908688	384222204							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623234	OCCN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)c(F)c1F	InChI=1S/C29H28F2N6O2/c1-2-25(39)33-21-7-3-5-19(17-21)22-8-4-6-20-18-32-29(35-28(20)22)34-23-9-10-24(27(31)26(23)30)37-13-11-36(12-14-37)15-16-38/h2-10,17-18,38H,1,11-16H2,(H,33,39)(H,32,34,35)	IDRGFNPZDVBSSE-UHFFFAOYSA-N	318916	US10172868, Compound C151::N-(3-(2-((2,3-difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C151::US11304957, Compound C151	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318916	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318916&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909640	384222205							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
623240	CN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)c(F)c1F	InChI=1S/C28H26F2N6O/c1-3-24(37)32-20-8-4-6-18(16-20)21-9-5-7-19-17-31-28(34-27(19)21)33-22-10-11-23(26(30)25(22)29)36-14-12-35(2)13-15-36/h3-11,16-17H,1,12-15H2,2H3,(H,32,37)(H,31,33,34)	WGIZXXVTHWXYIQ-UHFFFAOYSA-N	318917	US10172868, Compound C156::N-(3-(2-((2,3-difluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10653701, Compound C156::US11304957, Compound C156	Epidermal growth factor receptor	Human		<100							US Patent		10.7270/Q25141BX		aid1796605	US10172868	Qian, X; Zhu, Y	1/8/2019	5/15/2019	Neupharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318917	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318917&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117909324	384222206							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9MST,9MSS,9MSR,9KL4,9H46,9GL9,9GI9,9FRD,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C,7ZYP,7ZYN,7ZYM,6S8A,6S89,8A2A	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648078	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC1CN(C1)C(=O)C=C	InChI=1S/C21H19ClFN5O2/c1-3-20(29)28-9-13(10-28)26-18-7-14-17(8-19(18)30-2)24-11-25-21(14)27-12-4-5-16(23)15(22)6-12/h3-8,11,13,26H,1,9-10H2,2H3,(H,24,25,27)	AFTRDMOBKAMKFT-UHFFFAOYSA-N	330399	N6-(1-acryloylazetidin-3-yl)-N4-(3-chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine ::US9725439, 1	Epidermal growth factor receptor	Homo sapiens		 0.300							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330399&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122432049	384575257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648080	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC1CCN(CC1)C(=O)C=C	InChI=1S/C23H23ClFN5O2/c1-3-22(31)30-8-6-14(7-9-30)28-20-11-16-19(12-21(20)32-2)26-13-27-23(16)29-15-4-5-18(25)17(24)10-15/h3-5,10-14,28H,1,6-9H2,2H3,(H,26,27,29)	LCMWDJWASCJFQB-UHFFFAOYSA-N	330400	N6-(1-acryloylpiperidin-4-yl)-N4-(3-chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine::US9725439, 2	Epidermal growth factor receptor	Homo sapiens		 0.200							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330400&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91667519	384575258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648082	Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC4CN(C4)C(=O)C=C)cc23)cc1Cl	InChI=1S/C24H23ClFN5O3/c1-2-23(32)31-10-15(11-31)29-21-8-17-20(9-22(21)34-16-5-6-33-12-16)27-13-28-24(17)30-14-3-4-19(26)18(25)7-14/h2-4,7-9,13,15-16,29H,1,5-6,10-12H2,(H,27,28,30)/t16-/m0/s1	RSWAKAGASMNZDR-INIZCTEOSA-N	330401	(S)&#151;N6-(1-acryloylazetidin-3-yl)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine::US9725439, 3	Epidermal growth factor receptor	Homo sapiens		 0.200							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122422284	384575259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648084	Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC4CCN(CC4)C(=O)C=C)cc23)cc1Cl	InChI=1S/C26H27ClFN5O3/c1-2-25(34)33-8-5-16(6-9-33)31-23-12-19-22(13-24(23)36-18-7-10-35-14-18)29-15-30-26(19)32-17-3-4-21(28)20(27)11-17/h2-4,11-13,15-16,18,31H,1,5-10,14H2,(H,29,30,32)/t18-/m0/s1	FCWLXDKCXIPXIN-SFHVURJKSA-N	330402	(S)&#151;N6-(1-acryloylpiperidin-4-yl)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine::US9725439, 4	Epidermal growth factor receptor	Homo sapiens		 0.400							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122422223	384575260							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648088	COc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC1CCN(CC1)C(=O)C=C	InChI=1S/C29H29ClN6O3/c1-3-28(37)36-12-9-19(10-13-36)34-25-15-22-24(16-27(25)38-2)32-18-33-29(22)35-20-7-8-26(23(30)14-20)39-17-21-6-4-5-11-31-21/h3-8,11,14-16,18-19,34H,1,9-10,12-13,17H2,2H3,(H,32,33,35)	VVVBRNOABHGGMM-UHFFFAOYSA-N	330406	1-(4-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-methoxyquinazoline-6-ylamino)piperidin-1-yl)prop-2-ene-1-one::US9725439, 8	Epidermal growth factor receptor	Homo sapiens		 0.600							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330406&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122422234	384575264							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648093	COc1cc2ncnc(Nc3cccc(c3)C(C)=O)c2cc1NC1CN(C1)C(=O)C=C	InChI=1S/C23H23N5O3/c1-4-22(30)28-11-17(12-28)26-20-9-18-19(10-21(20)31-3)24-13-25-23(18)27-16-7-5-6-15(8-16)14(2)29/h4-10,13,17,26H,1,11-12H2,2-3H3,(H,24,25,27)	WIRGZYXZMXHDLS-UHFFFAOYSA-N	330411	 N4-(3-acetylphenyl)-N6-(1-acryloylazetidin-3-yl)-7-methoxyquinazoline-4,6-diamine::US9725439, 13	Epidermal growth factor receptor	Homo sapiens		 0.100							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117983743	384575269							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648096	COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1NC1CCN(CC1)C(=O)C=C	InChI=1S/C23H24BrN5O2/c1-3-22(30)29-9-7-16(8-10-29)27-20-12-18-19(13-21(20)31-2)25-14-26-23(18)28-17-6-4-5-15(24)11-17/h3-6,11-14,16,27H,1,7-10H2,2H3,(H,25,26,28)	ZMUBWQYTAFNXON-UHFFFAOYSA-N	330413	N6-(1-acryloylpiperidin-4-yl)-N4-(3-bromophenyl)-7-methoxyquinazoline-4,6-diamine::US9725439, 15	Epidermal growth factor receptor	Homo sapiens		 0.300							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330413&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117983789	384575271							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648099	COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC1CCN(CC1)C(=O)C=C	InChI=1S/C25H27ClFN5O3/c1-3-24(33)32-8-6-16(7-9-32)30-22-13-18-21(14-23(22)35-11-10-34-2)28-15-29-25(18)31-17-4-5-20(27)19(26)12-17/h3-5,12-16,30H,1,6-11H2,2H3,(H,28,29,31)	HYXRUTWCMWFLIL-UHFFFAOYSA-N	330415	N6-(1-acryloylpiperidin-4-yl)-N4-(3-chloro-4-fluorophenyl)-7-(2-methoxyethoxy)quinazoline-4,6-diamine  ::US9725439, 17	Epidermal growth factor receptor	Homo sapiens		 0.200							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330415&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122432019	384575273							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
648102	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1SC1CN(C1)C(=O)C=C	InChI=1S/C21H18ClFN4O2S/c1-3-20(28)27-9-13(10-27)30-19-7-14-17(8-18(19)29-2)24-11-25-21(14)26-12-4-5-16(23)15(22)6-12/h3-8,11,13H,1,9-10H2,2H3,(H,24,25,26)	QTPDNEFBIKGJSB-UHFFFAOYSA-N	330417	6-(1-acryloylazetidin-3-yl)thio-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazoline-4-amine  ::US9725439, 19	Epidermal growth factor receptor	Homo sapiens		 0.400							US Patent		10.7270/Q2FQ9ZQ9		aid1796863	US9725439	Xiao, D; Zhu, Y; Hu, Y; Wang, H; Li, J; Peng, Y; Zhang, H; Luo, H; Kong, F; Han, Y	8/8/2017	6/12/2019	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=330417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=330417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122422275	384575275							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650478	COc1ccc(cc1)N(C)c1nc(C)nc2oc(C)cc12	InChI=1S/C16H17N3O2/c1-10-9-14-15(17-11(2)18-16(14)21-10)19(3)12-5-7-13(20-4)8-6-12/h5-9H,1-4H3	KVMLMFRXRZLEGU-UHFFFAOYSA-N	50022542	CHEMBL3297898::US10189853, Compound 1	Epidermal growth factor receptor	Homo sapiens		 68.2							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44611919	242042451		CHEMBL3297898					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650481	COc1ccc(N(C)c2nc(C)nc3oc(C)cc23)c(OC)c1	InChI=1S/C17H19N3O3/c1-10-8-13-16(18-11(2)19-17(13)23-10)20(3)14-7-6-12(21-4)9-15(14)22-5/h6-9H,1-5H3	ZTPYIOAESPUXFH-UHFFFAOYSA-N	50069103	CHEMBL3403509::US10189853, Compound 2	Epidermal growth factor receptor	Homo sapiens		 162							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069103&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729842	313072158		CHEMBL3403509					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650484	COc1ccc(cc1OC)N(C)c1nc(C)nc2oc(C)cc12	InChI=1S/C17H19N3O3/c1-10-8-13-16(18-11(2)19-17(13)23-10)20(3)12-6-7-14(21-4)15(9-12)22-5/h6-9H,1-5H3	WBIIAZNRHKEMQF-UHFFFAOYSA-N	50069102	CHEMBL3403510::US10189853, Compound 3	Epidermal growth factor receptor	Homo sapiens		 90.3							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069102&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729843	313072157		CHEMBL3403510					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650487	COc1cc(cc(OC)c1OC)N(C)c1nc(C)nc2oc(C)cc12	InChI=1S/C18H21N3O4/c1-10-7-13-17(19-11(2)20-18(13)25-10)21(3)12-8-14(22-4)16(24-6)15(9-12)23-5/h7-9H,1-6H3	GNKOYELZMMGVRH-UHFFFAOYSA-N	50069101	CHEMBL3403511::US10189853, Compound 4	Epidermal growth factor receptor	Homo sapiens		>500							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069101&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729844	313072156		CHEMBL3403511					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650490	CN(c1ccc2OCOc2c1)c1nc(C)nc2oc(C)cc12	InChI=1S/C16H15N3O3/c1-9-6-12-15(17-10(2)18-16(12)22-9)19(3)11-4-5-13-14(7-11)21-8-20-13/h4-7H,8H2,1-3H3	MLNZPKUVAATQRY-UHFFFAOYSA-N	50069100	CHEMBL3403512::US10189853, Compound 5	Epidermal growth factor receptor	Homo sapiens		 298							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069100&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729845	313072155		CHEMBL3403512					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650493	CN(c1ccc2CCOc2c1)c1nc(C)nc2oc(C)cc12	InChI=1S/C17H17N3O2/c1-10-8-14-16(18-11(2)19-17(14)22-10)20(3)13-5-4-12-6-7-21-15(12)9-13/h4-5,8-9H,6-7H2,1-3H3	AMILNSQCJWLQJG-UHFFFAOYSA-N	331860	US10189853, Compound 6	Epidermal growth factor receptor	Homo sapiens		 226							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=331860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=331860&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			138403687	384576600							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650496	CN(c1ccc2ccoc2c1)c1nc(C)nc2oc(C)cc12	InChI=1S/C17H15N3O2/c1-10-8-14-16(18-11(2)19-17(14)22-10)20(3)13-5-4-12-6-7-21-15(12)9-13/h4-9H,1-3H3	HFJIWOVMXXZSKT-UHFFFAOYSA-N	331862	US10189853, Compound 7	Epidermal growth factor receptor	Homo sapiens		 307							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=331862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=331862&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			138403688	384576602							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650499	COc1ccc2NC(Cc2c1)N(C)c1nc(C)nc2oc(C)cc12	InChI=1S/C18H20N4O2/c1-10-7-14-17(19-11(2)20-18(14)24-10)22(3)16-9-12-8-13(23-4)5-6-15(12)21-16/h5-8,16,21H,9H2,1-4H3	WJOBXFAFXPJZEZ-UHFFFAOYSA-N	331864	US10189853, Compound 8	Epidermal growth factor receptor	Homo sapiens		 103							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=331864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=331864&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			138403689	384576604							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650502	COc1ccc2n(ccc2c1)-c1nc(C)nc2oc(C)cc12	InChI=1S/C17H15N3O2/c1-10-8-14-16(18-11(2)19-17(14)22-10)20-7-6-12-9-13(21-3)4-5-15(12)20/h4-9H,1-3H3	UDKMOAHOTPOVJU-UHFFFAOYSA-N	50069095	CHEMBL3403516::US10189853, Compound 9	Epidermal growth factor receptor	Homo sapiens		>500							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069095&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729849	313072150		CHEMBL3403516					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650505	COc1ccc2N(CCCc2c1)c1nc(C)nc2oc(C)cc12	InChI=1S/C18H19N3O2/c1-11-9-15-17(19-12(2)20-18(15)23-11)21-8-4-5-13-10-14(22-3)6-7-16(13)21/h6-7,9-10H,4-5,8H2,1-3H3	OYHXDIYGCSLVFT-UHFFFAOYSA-N	50069096	CHEMBL3403517::US10189853, Compound 10	Epidermal growth factor receptor	Homo sapiens		 3.40							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069096&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729850	313072151		CHEMBL3403517					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650508	CC(C)Oc1ccc(cc1)N(C)c1nc(C)nc2oc(C)cc12	InChI=1S/C18H21N3O2/c1-11(2)22-15-8-6-14(7-9-15)21(5)17-16-10-12(3)23-18(16)20-13(4)19-17/h6-11H,1-5H3	NTMALOHZZAUBAI-UHFFFAOYSA-N	50069097	CHEMBL3403518::US10189853, Compound 11	Epidermal growth factor receptor	Homo sapiens		 102							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069097&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729851	313072152		CHEMBL3403518					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650511	CCOc1ccc(cc1)N(C)c1nc(C)nc2oc(C)cc12	InChI=1S/C17H19N3O2/c1-5-21-14-8-6-13(7-9-14)20(4)16-15-10-11(2)22-17(15)19-12(3)18-16/h6-10H,5H2,1-4H3	VTLMUUYKCYKXDZ-UHFFFAOYSA-N	50069098	CHEMBL3403519::US10189853, Compound 12	Epidermal growth factor receptor	Homo sapiens		>500							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069098&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118729852	313072153		CHEMBL3403519					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650515	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cccc(F)c23)c1C	InChI=1S/C22H27FN4O2/c1-5-27(6-2)11-10-24-22(29)19-13(3)18(25-14(19)4)12-15-20-16(23)8-7-9-17(20)26-21(15)28/h7-9,12,25H,5-6,10-11H2,1-4H3,(H,24,29)(H,26,28)/b15-12-	UQQZPUPMXFCRML-QINSGFPZSA-N	158478	US10189853, sunitinib::US9029401, Sunitinib::US9695181, Sunitinib	Epidermal growth factor receptor	Homo sapiens		 172							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158478&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			46233298	254816949							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
650518	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens		 1.20							US Patent		10.7270/Q2RX9F5S		aid1796887	US10189853	Gangjee, A	1/29/2019	6/12/2019	Duquesne University of the Holy Spirit	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651591	COCCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H27ClFN5O3/c1-31(2)9-4-6-23(32)30-21-13-17-20(14-22(21)34-11-5-10-33-3)27-15-28-24(17)29-16-7-8-19(26)18(25)12-16/h4,6-8,12-15H,5,9-11H2,1-3H3,(H,30,32)(H,27,28,29)/b6-4+	ASJKJRLGRZGMDR-GQCTYLIASA-N	332536	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(3-methoxypropoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 1	Epidermal growth factor receptor	Homo sapiens		 0.765							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332536&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900282	384577250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651593	COC[C@@H](C)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H27ClFN5O3/c1-15(13-33-4)34-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(28-14-27-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14-15H,9,13H2,1-4H3,(H,30,32)(H,27,28,29)/b6-5+/t15-/m1/s1	UHGKHVDHBHYHFY-LLYBFZRZSA-N	332537	(R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-methoxy-1-methylethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 2	Epidermal growth factor receptor	Homo sapiens		 0.950							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332537&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900305	384577251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651595	COC[C@H](C)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H27ClFN5O3/c1-15(13-33-4)34-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(28-14-27-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14-15H,9,13H2,1-4H3,(H,30,32)(H,27,28,29)/b6-5+/t15-/m0/s1	UHGKHVDHBHYHFY-NFAHFFEMSA-N	332538	(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-methoxy-1-methylethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 3	Epidermal growth factor receptor	Homo sapiens		 2.73							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900306	384577252							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651597	CCOCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H27ClFN5O3/c1-4-33-10-11-34-22-14-20-17(13-21(22)30-23(32)6-5-9-31(2)3)24(28-15-27-20)29-16-7-8-19(26)18(25)12-16/h5-8,12-15H,4,9-11H2,1-3H3,(H,30,32)(H,27,28,29)/b6-5+	DBDXRFYGZAEXEW-AATRIKPKSA-N	332539	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-ethoxyethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 4	Epidermal growth factor receptor	Homo sapiens		 0.699							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900298	384577253							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651599	CCCOCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C25H29ClFN5O3/c1-4-10-34-11-12-35-23-15-21-18(14-22(23)31-24(33)6-5-9-32(2)3)25(29-16-28-21)30-17-7-8-20(27)19(26)13-17/h5-8,13-16H,4,9-12H2,1-3H3,(H,31,33)(H,28,29,30)/b6-5+	HFSSHOGNUBJRFO-AATRIKPKSA-N	332540	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-propoxyethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 5	Epidermal growth factor receptor	Homo sapiens		 2.85							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900244	384577254							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651601	CC(C)OCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C25H29ClFN5O3/c1-16(2)34-10-11-35-23-14-21-18(13-22(23)31-24(33)6-5-9-32(3)4)25(29-15-28-21)30-17-7-8-20(27)19(26)12-17/h5-8,12-16H,9-11H2,1-4H3,(H,31,33)(H,28,29,30)/b6-5+	WCHJBACVJHXLGX-AATRIKPKSA-N	332541	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-isopropoxyethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 6	Epidermal growth factor receptor	Homo sapiens		 1.54							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332541&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900245	384577255							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651603	CCOCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C26H29N5O3/c1-5-19-9-7-10-20(15-19)29-26-21-16-23(30-25(32)11-8-12-31(3)4)24(34-14-13-33-6-2)17-22(21)27-18-28-26/h1,7-11,15-18H,6,12-14H2,2-4H3,(H,30,32)(H,27,28,29)/b11-8+	IFUPZYWAOYZTHS-DHZHZOJOSA-N	332542	(E)-N-(7-(2-ethoxyethoxy)-4-(3-ethynylphenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 10	Epidermal growth factor receptor	Homo sapiens		 0.771							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900261	384577256							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651605	CCOCCOc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C31H33ClFN5O4/c1-4-40-13-14-41-29-18-26-24(17-27(29)37-30(39)9-6-12-38(2)3)31(35-20-34-26)36-23-10-11-28(25(32)16-23)42-19-21-7-5-8-22(33)15-21/h5-11,15-18,20H,4,12-14,19H2,1-3H3,(H,37,39)(H,34,35,36)/b9-6+	DEKAVWSCKVKTIM-RMKNXTFCSA-N	332543	(E) N (4 (4 (3 fluorobenzyloxy)3-chlorophenylamino)-7-(2-ethoxyethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 11	Epidermal growth factor receptor	Homo sapiens		 154							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332543&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900269	384577257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651607	CCOCCOc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C30H33ClN6O4/c1-4-39-14-15-40-28-18-25-23(17-26(28)36-29(38)9-7-13-37(2)3)30(34-20-33-25)35-21-10-11-27(24(31)16-21)41-19-22-8-5-6-12-32-22/h5-12,16-18,20H,4,13-15,19H2,1-3H3,(H,36,38)(H,33,34,35)/b9-7+	XPZGTHUXSPUGHN-VQHVLOKHSA-N	332544	(E)-N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-(2-ethoxyethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide ::US10196365, Compound 12	Epidermal growth factor receptor	Homo sapiens		 10.2							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900273	384577258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651609	CCOCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C/Cl	InChI=1S/C21H19Cl2FN4O3/c1-2-30-7-8-31-19-11-17-14(10-18(19)28-20(29)5-6-22)21(26-12-25-17)27-13-3-4-16(24)15(23)9-13/h3-6,9-12H,2,7-8H2,1H3,(H,28,29)(H,25,26,27)/b6-5-	NJHDYUHKGOBVKW-WAYWQWQTSA-N	332545	(E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-ethoxyethoxy)quinazolin-6-yl)-4-(diethylamino)but-2-enamide ::US10196365, Compound 33	Epidermal growth factor receptor	Homo sapiens		 1.49							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=332545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=332545&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118900294	384577259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
651611	CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1	InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1	ULXXDDBFHOBEHA-CWDCEQMOSA-N	50322823	(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide::AFATINIB::CHEMBL1173655::US10085983, Compound BIBW2992::US10196365, Afatinib::US10435400, Compound BIBW2992::US9388170, Afatinib::US9890168, Compound BIBW2992::WO2022090481, Example afatinib	Epidermal growth factor receptor	Homo sapiens		 0.965							US Patent		10.7270/Q2GH9M2W		aid1796911	US10196365	Hong, J; Xu, X; Le, X; Zhang, Z	2/5/2019	6/14/2019	ARROMAX PHARMATECH CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322823&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0WM	4G5J	10184653	104144352	61390	CHEMBL1173655	DB08916	5667		ZINC03976838	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653328	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens		 1.60							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653331	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	Epidermal growth factor receptor	Homo sapiens		 7.60							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653334	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	Epidermal growth factor receptor	Homo sapiens		 7.60							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653337	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	Epidermal growth factor receptor	Homo sapiens		 7.60							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653340	CN1CCC2(CC(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)C=C)CO2)CC1	InChI=1S/C27H29ClFN5O3/c1-3-25(35)33-23-11-19-22(30-16-31-26(19)32-18-4-5-21(29)20(28)10-18)12-24(23)36-14-17-13-27(37-15-17)6-8-34(2)9-7-27/h3-5,10-12,16-17H,1,6-9,13-15H2,2H3,(H,33,35)(H,30,31,32)	JGSKJUYVTDKFKT-UHFFFAOYSA-N	333446	N-[4-(3-chloro-4- fluorophenylamino)-7-((8-methyl-1- oxa-8-azaspiro[4.5]decan-3- yl)methoxy)quinazolin-6-yl]- acrylamide::US10507209, Compound 6::US9730934, Compound 6	Epidermal growth factor receptor	Homo sapiens		 1.000							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=333446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=333446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56933169	384985642							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653343	CN1CCC2(CCC(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)C=C)O2)CC1	InChI=1S/C27H29ClFN5O3/c1-3-25(35)33-23-13-19-22(30-16-31-26(19)32-17-4-5-21(29)20(28)12-17)14-24(23)36-15-18-6-7-27(37-18)8-10-34(2)11-9-27/h3-5,12-14,16,18H,1,6-11,15H2,2H3,(H,33,35)(H,30,31,32)	JFUDQORFBVGLMB-UHFFFAOYSA-N	333447	N-[4-(3-chloro-4- fluorophenylamino)-7-(8-methyl-1- oxa-8-azaspiro[4.5]decan-2- ylmethoxy)quinazolin-6-yl]- acrylamide::US10507209, Compound 7::US9730934, Compound 7	Epidermal growth factor receptor	Homo sapiens		 0.930							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=333447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=333447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56933170	384985643							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653346	CN1C[C@H]2[C@H](CCOc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)C=C)[C@H]2C1	InChI=1S/C25H25ClFN5O2/c1-3-24(33)31-22-9-16-21(10-23(22)34-7-6-15-17-11-32(2)12-18(15)17)28-13-29-25(16)30-14-4-5-20(27)19(26)8-14/h3-5,8-10,13,15,17-18H,1,6-7,11-12H2,2H3,(H,31,33)(H,28,29,30)/t15-,17-,18+	UAXLMFNKXDVZKH-XGWQRUHWSA-N	333448	N-[4-(3-chloro-4- fluorophenylamino)-7-(2- ((1R,5S,6S)-3-methyl-3- azabicyclo[3.1.0]hexan-6- ylethoxy)quinazolin-6-yl]- acrylamide::US10507209, Compound 8::US9730934, Compound 8	Epidermal growth factor receptor	Homo sapiens		 0.660							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=333448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=333448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56933171	384985644							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653349	CN1CC2CCC(C1)C2CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C	InChI=1S/C27H29ClFN5O2/c1-3-26(35)33-24-11-20-23(30-15-31-27(20)32-18-6-7-22(29)21(28)10-18)12-25(24)36-9-8-19-16-4-5-17(19)14-34(2)13-16/h3,6-7,10-12,15-17,19H,1,4-5,8-9,13-14H2,2H3,(H,33,35)(H,30,31,32)	FGYHOZIXSUEJDM-UHFFFAOYSA-N	333449	N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(3-methyl- 3-azabicyclo[3.2.1]octan-8- yl)ethoxy)quinazolin-6-yl]- acrylamide::US10507209, Compound 11::US9730934, Compound 11	Epidermal growth factor receptor	Homo sapiens		 0.800							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=333449	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=333449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56933187	384985645							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653352	CN1CCC2(CC2CCOc2cc3ncnc(Nc4ccc(F)c(Cl)c4)c3cc2NC(=O)C=C)CC1	InChI=1S/C27H29ClFN5O2/c1-3-25(35)33-23-13-19-22(30-16-31-26(19)32-18-4-5-21(29)20(28)12-18)14-24(23)36-11-6-17-15-27(17)7-9-34(2)10-8-27/h3-5,12-14,16-17H,1,6-11,15H2,2H3,(H,33,35)(H,30,31,32)	YAPFODKXVWEFPW-UHFFFAOYSA-N	333465	N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(6-methyl- 6-azaspiro[2.5]octan-1- yl)ethoxy)quinazolin-6-yl]- acrylamide::US10507209, Compound 14::US9730934, Compound 14	Epidermal growth factor receptor	Homo sapiens		 0.390							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=333465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=333465&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56933202	384985661							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653355	CN1CCC2(CC(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)C=C)C2)CC1	InChI=1S/C27H29ClFN5O2/c1-3-25(35)33-23-11-19-22(30-16-31-26(19)32-18-4-5-21(29)20(28)10-18)12-24(23)36-15-17-13-27(14-17)6-8-34(2)9-7-27/h3-5,10-12,16-17H,1,6-9,13-15H2,2H3,(H,33,35)(H,30,31,32)	KJBZQIKLKWQVLL-UHFFFAOYSA-N	333466	N-[4-(3-chloro-4- fluorophenylamino)-7-((7-methyl-7- azaspiro[3.5]nonan-2- yl)methoxy)quinazolin-6-yl]- acrylamide::US10507209, Compound 18::US9730934, Compound 18	Epidermal growth factor receptor	Homo sapiens		 1.000							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=333466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=333466&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56933206	384985662							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
653358	CN1CCC2(CC(CCOc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)C=C)C2)CC1	InChI=1S/C28H31ClFN5O2/c1-3-26(36)34-24-13-20-23(31-17-32-27(20)33-19-4-5-22(30)21(29)12-19)14-25(24)37-11-6-18-15-28(16-18)7-9-35(2)10-8-28/h3-5,12-14,17-18H,1,6-11,15-16H2,2H3,(H,34,36)(H,31,32,33)	KTOOFDBYBSZFDL-UHFFFAOYSA-N	333467	N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(7-methyl- 7-azaspiro[3.5]nonan-2- yl)ethoxy)quinazolin-6-yl]- acrylamide::US10507209, Compound 19::US9730934, Compound 19	Epidermal growth factor receptor	Homo sapiens		 0.560							US Patent		10.7270/Q21C200G		aid1796957	US9730934	Huang, Z; Dong, Y	8/15/2017	6/23/2019	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=333467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=333467&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56933218	384985663							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673386	COc1ccccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H18F3N5O2/c1-3-18(30)26-13-7-6-8-14(11-13)27-19-15(21(22,23)24)12-25-20(29-19)28-16-9-4-5-10-17(16)31-2/h3-12H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	ARSGAAANDMOADX-UHFFFAOYSA-N	202369	US10081606, Compound I-1::US9238629, I-1::US9765038, Compound I-1	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56965025	319495463							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673388	COc1ccccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H17F3N4O3/c1-3-18(29)26-13-7-6-8-14(11-13)31-19-15(21(22,23)24)12-25-20(28-19)27-16-9-4-5-10-17(16)30-2/h3-12H,1H2,2H3,(H,26,29)(H,25,27,28)	KGGXRCWBXUHQBM-UHFFFAOYSA-N	202370	US10081606, Compound I-2::US9238629, I-2::US9765038, Compound I-2	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336077	319495464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673390	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H20F3N5O3/c1-4-19(31)27-13-6-5-7-14(10-13)28-20-16(22(23,24)25)12-26-21(30-20)29-17-9-8-15(32-2)11-18(17)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	ARWJHMPQGVRJGR-UHFFFAOYSA-N	202371	US10081606, Compound I-3::US9238629, I-3::US9765038, Compound I-3	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336078	319495465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673392	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22ClN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	AWLYEWOENDLBPJ-UHFFFAOYSA-N	202372	US10081606, Compound I-4::US9238629, I-4::US9765038, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336218	319495466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673394	COc1ccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22BrN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	UKFLBAQMJNODAB-UHFFFAOYSA-N	202373	US10081606, Compound I-5::US9238629, I-5::US9765038, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336219	319495467							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673396	COc1cccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H19BrN4O4/c1-4-18(27)24-13-7-5-8-14(11-13)30-20-15(22)12-23-21(26-20)25-16-9-6-10-17(28-2)19(16)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	MOQWLDSTRHMSCL-UHFFFAOYSA-N	202374	US10081606, Compound I-6::US9238629, I-14::US9238629, I-6::US9765038, Compound I-6	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336220	319495468							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673398	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21ClN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	KKXHOHZIJWZIMH-UHFFFAOYSA-N	202375	US10081606, Compound I-7::US9238629, I-7::US9765038, Compound I-7	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336221	319495469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673400	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21BrN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	YVPOPEGFKSLPQP-UHFFFAOYSA-N	202376	US10081606, Compound I-8::US9238629, I-8::US9765038, Compound I-8	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336222	319495470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673402	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H19F3N4O4/c1-4-19(30)27-13-6-5-7-15(10-13)33-20-16(22(23,24)25)12-26-21(29-20)28-17-9-8-14(31-2)11-18(17)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	YQRLADVWFUXYQX-UHFFFAOYSA-N	202377	US10081606, Compound I-9::US9238629, I-9::US9765038, Compound I-9	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336223	319495471							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673404	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H21F3N4O5/c1-5-18(31)28-13-7-6-8-14(11-13)35-21-15(23(24,25)26)12-27-22(30-21)29-16-9-10-17(32-2)20(34-4)19(16)33-3/h5-12H,1H2,2-4H3,(H,28,31)(H,27,29,30)	BJXUJZVUNLHQJX-UHFFFAOYSA-N	202378	US10081606, Compound I-10::US9238629, I-10::US9765038, Compound I-10	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202378&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333995	319495472							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673406	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H22F3N5O4/c1-5-18(32)28-13-7-6-8-14(11-13)29-21-15(23(24,25)26)12-27-22(31-21)30-16-9-10-17(33-2)20(35-4)19(16)34-3/h5-12H,1H2,2-4H3,(H,28,32)(H2,27,29,30,31)	XTEXGVCQXOYDOW-UHFFFAOYSA-N	202379	US10081606, Compound I-11::US9238629, I-11::US9765038, Compound I-11	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333996	319495473							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673408	COc1ccccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H17ClN4O3/c1-3-18(26)23-13-7-6-8-14(11-13)28-19-15(21)12-22-20(25-19)24-16-9-4-5-10-17(16)27-2/h3-12H,1H2,2H3,(H,23,26)(H,22,24,25)	DSRXZMGDJDQWJM-UHFFFAOYSA-N	202380	US10081606, Compound I-12::US9238629, I-12::US9765038, Compound I-12	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333997	319495474							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673410	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19BrN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	OKWMEKZLQMLGEO-UHFFFAOYSA-N	202381	US10081606, Compound I-13::US9238629, I-13::US9765038, Compound I-13	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333998	319495475							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673412	COc1cccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H20BrN5O3/c1-4-18(28)24-13-7-5-8-14(11-13)25-20-15(22)12-23-21(27-20)26-16-9-6-10-17(29-2)19(16)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	GZIGQTZRHLRBJL-UHFFFAOYSA-N	285865	US10081606, Compound I-14::US9765038, Compound I-14	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=285865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=285865&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333999	378169502							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673414	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19ClN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	UVQSPGYTMSYCFZ-UHFFFAOYSA-N	202383	US10081606, Compound I-15::US9238629, I-15::US9765038, Compound I-15	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334000	319495476							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673416	COc1cccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H20F3N5O3/c1-4-18(31)27-13-7-5-8-14(11-13)28-20-15(22(23,24)25)12-26-21(30-20)29-16-9-6-10-17(32-2)19(16)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	NBLFLERZTPRKQT-UHFFFAOYSA-N	202384	US10081606, Compound I-16::US9238629, I-16::US9765038, Compound I-16	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334304	319495477							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673418	COc1cccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c1OC	InChI=1S/C21H19ClN4O4/c1-4-18(27)24-13-7-5-8-14(11-13)30-20-15(22)12-23-21(26-20)25-16-9-6-10-17(28-2)19(16)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	JNDJZQKLKVLDLW-UHFFFAOYSA-N	285868	US10081606, Compound I-17::US9765038, Compound I-17	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=285868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=285868&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334157	378169505							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673420	COc1ccccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H18ClN5O2/c1-3-18(27)23-13-7-6-8-14(11-13)24-19-15(21)12-22-20(26-19)25-16-9-4-5-10-17(16)28-2/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	IJBMVFJGJFRXOX-UHFFFAOYSA-N	202386	US10081606, Compound I-18::US9238629, I-18::US9765038, Compound I-18	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334158	319495479							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673422	COc1ccccc1Nc1ncc(F)c(Oc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H17FN4O3/c1-3-18(26)23-13-7-6-8-14(11-13)28-19-15(21)12-22-20(25-19)24-16-9-4-5-10-17(16)27-2/h3-12H,1H2,2H3,(H,23,26)(H,22,24,25)	XSYRRKUEQTWUCQ-UHFFFAOYSA-N	202387	US10081606, Compound I-19::US9238629, I-19::US9765038, Compound I-19	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334159	319495480							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673424	COc1ccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H20BrN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-17-9-8-15(29-2)11-18(17)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	HPWXLWYAEGDGKI-UHFFFAOYSA-N	202388	US10081606, Compound I-20::US9238629, I-20::US9765038, Compound I-20	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202388&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334160	319495481							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673426	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H20ClN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-17-9-8-15(29-2)11-18(17)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	UGZHYAQGGADKAK-UHFFFAOYSA-N	202389	US10081606, Compound I-21::US9238629, I-21::US9765038, Compound I-21	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334161	319495482							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673428	COc1ccccc1Nc1ncc(Br)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H18BrN5O2/c1-3-18(27)23-13-7-6-8-14(11-13)24-19-15(21)12-22-20(26-19)25-16-9-4-5-10-17(16)28-2/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	FMTXHOXUJYVAMG-UHFFFAOYSA-N	202390	US10081606, Compound I-22::US9238629, I-22::US9765038, Compound I-22	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202390&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334303	319495483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673430	COc1cccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H19F3N4O4/c1-4-18(30)27-13-7-5-8-14(11-13)33-20-15(22(23,24)25)12-26-21(29-20)28-16-9-6-10-17(31-2)19(16)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	HIMGGUFXIBERNV-UHFFFAOYSA-N	202391	US10081606, Compound I-23::US9238629, I-23::US9765038, Compound I-23	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202391&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334156	319495484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673432	COc1ccccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H18F3N5O2/c1-3-18(30)26-13-7-6-8-14(11-13)27-19-15(21(22,23)24)12-25-20(29-19)28-16-9-4-5-10-17(16)31-2/h3-12H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	ARSGAAANDMOADX-UHFFFAOYSA-N	202369	US10081606, Compound I-1::US9238629, I-1::US9765038, Compound I-1	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56965025	319495463							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673433	COc1ccccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C21H17F3N4O3/c1-3-18(29)26-13-7-6-8-14(11-13)31-19-15(21(22,23)24)12-25-20(28-19)27-16-9-4-5-10-17(16)30-2/h3-12H,1H2,2H3,(H,26,29)(H,25,27,28)	KGGXRCWBXUHQBM-UHFFFAOYSA-N	202370	US10081606, Compound I-2::US9238629, I-2::US9765038, Compound I-2	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336077	319495464							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673434	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H20F3N5O3/c1-4-19(31)27-13-6-5-7-14(10-13)28-20-16(22(23,24)25)12-26-21(30-20)29-17-9-8-15(32-2)11-18(17)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	ARWJHMPQGVRJGR-UHFFFAOYSA-N	202371	US10081606, Compound I-3::US9238629, I-3::US9765038, Compound I-3	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336078	319495465							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673435	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22ClN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	AWLYEWOENDLBPJ-UHFFFAOYSA-N	202372	US10081606, Compound I-4::US9238629, I-4::US9765038, Compound I-4	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336218	319495466							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673436	COc1ccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H22BrN5O4/c1-5-18(29)25-13-7-6-8-14(11-13)26-21-15(23)12-24-22(28-21)27-16-9-10-17(30-2)20(32-4)19(16)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	UKFLBAQMJNODAB-UHFFFAOYSA-N	202373	US10081606, Compound I-5::US9238629, I-5::US9765038, Compound I-5	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336219	319495467							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673437	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21ClN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	KKXHOHZIJWZIMH-UHFFFAOYSA-N	202375	US10081606, Compound I-7::US9238629, I-7::US9765038, Compound I-7	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336221	319495469							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673438	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1OC	InChI=1S/C22H21BrN4O5/c1-5-18(28)25-13-7-6-8-14(11-13)32-21-15(23)12-24-22(27-21)26-16-9-10-17(29-2)20(31-4)19(16)30-3/h5-12H,1H2,2-4H3,(H,25,28)(H,24,26,27)	YVPOPEGFKSLPQP-UHFFFAOYSA-N	202376	US10081606, Compound I-8::US9238629, I-8::US9765038, Compound I-8	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336222	319495470							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673439	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C22H19F3N4O4/c1-4-19(30)27-13-6-5-7-15(10-13)33-20-16(22(23,24)25)12-26-21(29-20)28-17-9-8-14(31-2)11-18(17)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	YQRLADVWFUXYQX-UHFFFAOYSA-N	202377	US10081606, Compound I-9::US9238629, I-9::US9765038, Compound I-9	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336223	319495471							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673440	COc1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H21F3N4O5/c1-5-18(31)28-13-7-6-8-14(11-13)35-21-15(23(24,25)26)12-27-22(30-21)29-16-9-10-17(32-2)20(34-4)19(16)33-3/h5-12H,1H2,2-4H3,(H,28,31)(H,27,29,30)	BJXUJZVUNLHQJX-UHFFFAOYSA-N	202378	US10081606, Compound I-10::US9238629, I-10::US9765038, Compound I-10	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202378&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333995	319495472							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673441	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1OC	InChI=1S/C23H22F3N5O4/c1-5-18(32)28-13-7-6-8-14(11-13)29-21-15(23(24,25)26)12-27-22(31-21)30-16-9-10-17(33-2)20(35-4)19(16)34-3/h5-12H,1H2,2-4H3,(H,28,32)(H2,27,29,30,31)	XTEXGVCQXOYDOW-UHFFFAOYSA-N	202379	US10081606, Compound I-11::US9238629, I-11::US9765038, Compound I-11	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333996	319495473							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673442	COc1ccc(Nc2ncc(Br)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19BrN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	OKWMEKZLQMLGEO-UHFFFAOYSA-N	202381	US10081606, Compound I-13::US9238629, I-13::US9765038, Compound I-13	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57333998	319495475							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673443	COc1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H19ClN4O4/c1-4-19(27)24-13-6-5-7-15(10-13)30-20-16(22)12-23-21(26-20)25-17-9-8-14(28-2)11-18(17)29-3/h4-12H,1H2,2-3H3,(H,24,27)(H,23,25,26)	UVQSPGYTMSYCFZ-UHFFFAOYSA-N	202383	US10081606, Compound I-15::US9238629, I-15::US9765038, Compound I-15	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334000	319495476							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673444	COc1cccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H20F3N5O3/c1-4-18(31)27-13-7-5-8-14(11-13)28-20-15(22(23,24)25)12-26-21(30-20)29-16-9-6-10-17(32-2)19(16)33-3/h4-12H,1H2,2-3H3,(H,27,31)(H2,26,28,29,30)	NBLFLERZTPRKQT-UHFFFAOYSA-N	202384	US10081606, Compound I-16::US9238629, I-16::US9765038, Compound I-16	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334304	319495477							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673445	COc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1	InChI=1S/C21H20ClN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-17-9-8-15(29-2)11-18(17)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	UGZHYAQGGADKAK-UHFFFAOYSA-N	202389	US10081606, Compound I-21::US9238629, I-21::US9765038, Compound I-21	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334161	319495482							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673446	COc1ccccc1Nc1ncc(Br)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H18BrN5O2/c1-3-18(27)23-13-7-6-8-14(11-13)24-19-15(21)12-22-20(26-19)25-16-9-4-5-10-17(16)28-2/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	FMTXHOXUJYVAMG-UHFFFAOYSA-N	202390	US10081606, Compound I-22::US9238629, I-22::US9765038, Compound I-22	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202390&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334303	319495483							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
673447	COc1cccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC	InChI=1S/C22H19F3N4O4/c1-4-18(30)27-13-7-5-8-14(11-13)33-20-15(22(23,24)25)12-26-21(29-20)28-16-9-6-10-17(31-2)19(16)32-3/h4-12H,1H2,2-3H3,(H,27,30)(H,26,28,29)	HIMGGUFXIBERNV-UHFFFAOYSA-N	202391	US10081606, Compound I-23::US9238629, I-23::US9765038, Compound I-23	Epidermal growth factor receptor	Homo sapiens				>1000					US Patent		10.7270/Q26D5W3M		aid1797176	US9765038	Lee, K; Niu, D; Petter, RC; Singh, J	9/19/2017	7/29/2019	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=202391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=202391&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334156	319495484							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680833	C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1	InChI=1S/C22H21N3O4/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20/h1,3-5,12-15H,6-11H2,(H,23,24,25)	QQLKULDARVNMAL-UHFFFAOYSA-N	50391089	BPI-2009::CHEMBL2087361::Conmana::Icotinib::Lcotinib::US9783524, Icotinib	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391089	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391089&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			22024915	160870172		CHEMBL2087361				ZINC43207566	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680834	C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1	InChI=1S/C22H21N3O4/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20/h1,3-5,12-15H,6-11H2,(H,23,24,25)	QQLKULDARVNMAL-UHFFFAOYSA-N	50391089	BPI-2009::CHEMBL2087361::Conmana::Icotinib::Lcotinib::US9783524, Icotinib	Epidermal growth factor receptor	Homo sapiens		 1.23							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391089	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391089&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			22024915	160870172		CHEMBL2087361				ZINC43207566	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680837	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens		 179							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680838	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	Epidermal growth factor receptor	Homo sapiens		<0.508							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680842	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	AVL-301::CHEMBL3545308::CNX-419::CO-1686::Rociletinib::Tube721::US10167264, Compound CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4::US8975249, I-4::US9783524, CO-1686	Epidermal growth factor receptor	Homo sapiens		 13.7							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDL,5XDK	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680843	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	AVL-301::CHEMBL3545308::CNX-419::CO-1686::Rociletinib::Tube721::US10167264, Compound CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4::US8975249, I-4::US9783524, CO-1686	Epidermal growth factor receptor	Homo sapiens		 101							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDL,5XDK	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680847	COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(N)=O)n1)N1CCC(CC1)N(C)C	InChI=1S/C26H30ClN7O3/c1-33(2)16-10-12-34(13-11-16)17-8-9-21(22(14-17)37-3)31-26-29-15-19(27)25(32-26)30-20-7-5-4-6-18(20)23(35)24(28)36/h4-9,14-16H,10-13H2,1-3H3,(H2,28,36)(H2,29,30,31,32)	AMSONZZHZCNUHV-UHFFFAOYSA-N	270538	US10059688, Example 4::US9783524, Example 4	Epidermal growth factor receptor	Homo sapiens		 7.52							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055587	378152421							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680848	COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(N)=O)n1)N1CCC(CC1)N(C)C	InChI=1S/C26H30ClN7O3/c1-33(2)16-10-12-34(13-11-16)17-8-9-21(22(14-17)37-3)31-26-29-15-19(27)25(32-26)30-20-7-5-4-6-18(20)23(35)24(28)36/h4-9,14-16H,10-13H2,1-3H3,(H2,28,36)(H2,29,30,31,32)	AMSONZZHZCNUHV-UHFFFAOYSA-N	270538	US10059688, Example 4::US9783524, Example 4	Epidermal growth factor receptor	Homo sapiens		 45.1							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055587	378152421							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680852	COc1cc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)ccc1N1CCN(C)CC1	InChI=1S/C26H30ClN7O3/c1-32(2)25(36)23(35)18-7-5-6-8-20(18)30-24-19(27)16-28-26(31-24)29-17-9-10-21(22(15-17)37-4)34-13-11-33(3)12-14-34/h5-10,15-16H,11-14H2,1-4H3,(H2,28,29,30,31)	DIQHRPNVYBPCQW-UHFFFAOYSA-N	270539	2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-1-yl) phenylamino)pyrimidin-4- ylamino)phenyl)-N,N- dimethyl-2-oxoacetamide::US10059688, Example 61::US9783524, Example 61	Epidermal growth factor receptor	Homo sapiens		 38.2							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055101	378152422							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680853	COc1cc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)ccc1N1CCN(C)CC1	InChI=1S/C26H30ClN7O3/c1-32(2)25(36)23(35)18-7-5-6-8-20(18)30-24-19(27)16-28-26(31-24)29-17-9-10-21(22(15-17)37-4)34-13-11-33(3)12-14-34/h5-10,15-16H,11-14H2,1-4H3,(H2,28,29,30,31)	DIQHRPNVYBPCQW-UHFFFAOYSA-N	270539	2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-1-yl) phenylamino)pyrimidin-4- ylamino)phenyl)-N,N- dimethyl-2-oxoacetamide::US10059688, Example 61::US9783524, Example 61	Epidermal growth factor receptor	Homo sapiens		 756							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055101	378152422							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680857	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(=O)N(C)C)n1	InChI=1S/C24H23ClN6O4/c1-5-20(32)27-14-10-11-19(35-4)18(12-14)29-24-26-13-16(25)22(30-24)28-17-9-7-6-8-15(17)21(33)23(34)31(2)3/h5-13H,1H2,2-4H3,(H,27,32)(H2,26,28,29,30)	OKCOQQXHDZUFTL-UHFFFAOYSA-N	270540	N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacetyl) phenylamino)pyrimidin-2- ylamino)-4-methoxyphenyl) acrylamide::US10059688, Example 67::US9783524, Example 67	Epidermal growth factor receptor	Homo sapiens		 18.9							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055183	378152423							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680858	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(=O)N(C)C)n1	InChI=1S/C24H23ClN6O4/c1-5-20(32)27-14-10-11-19(35-4)18(12-14)29-24-26-13-16(25)22(30-24)28-17-9-7-6-8-15(17)21(33)23(34)31(2)3/h5-13H,1H2,2-4H3,(H,27,32)(H2,26,28,29,30)	OKCOQQXHDZUFTL-UHFFFAOYSA-N	270540	N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacetyl) phenylamino)pyrimidin-2- ylamino)-4-methoxyphenyl) acrylamide::US10059688, Example 67::US9783524, Example 67	Epidermal growth factor receptor	Homo sapiens		 273							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055183	378152423							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680862	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(=O)N(C)C)n1	InChI=1S/C29H33ClN8O4/c1-6-25(39)32-21-15-22(24(42-5)16-23(21)38-13-11-37(4)12-14-38)34-29-31-17-19(30)27(35-29)33-20-10-8-7-9-18(20)26(40)28(41)36(2)3/h6-10,15-17H,1,11-14H2,2-5H3,(H,32,39)(H2,31,33,34,35)	VMFMUJZRXZXYAH-UHFFFAOYSA-N	344704	Compound 74::US9783524, Example 74	Epidermal growth factor receptor	Homo sapiens		 15.8							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=344704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=344704&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055351	385450782							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680863	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(=O)N(C)C)n1	InChI=1S/C29H33ClN8O4/c1-6-25(39)32-21-15-22(24(42-5)16-23(21)38-13-11-37(4)12-14-38)34-29-31-17-19(30)27(35-29)33-20-10-8-7-9-18(20)26(40)28(41)36(2)3/h6-10,15-17H,1,11-14H2,2-5H3,(H,32,39)(H2,31,33,34,35)	VMFMUJZRXZXYAH-UHFFFAOYSA-N	344704	Compound 74::US9783524, Example 74	Epidermal growth factor receptor	Homo sapiens		 513							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=344704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=344704&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055351	385450782							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680867	CN(C)C(=O)C(=O)c1ccccc1Nc1nc(Nc2ccc3OCCN(C(=O)C=C)c3c2)ncc1Cl	InChI=1S/C25H23ClN6O4/c1-4-21(33)32-11-12-36-20-10-9-15(13-19(20)32)28-25-27-14-17(26)23(30-25)29-18-8-6-5-7-16(18)22(34)24(35)31(2)3/h4-10,13-14H,1,11-12H2,2-3H3,(H2,27,28,29,30)	KXPICMSXZCNILY-UHFFFAOYSA-N	270542	2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] oxazin-6-ylamino)-5- chloropyrimidin-4- ylamino)phenyl)-N,N- dimethyl-2-oxoacetamide::US10059688, Example 87::US9783524, Example 87	Epidermal growth factor receptor	Homo sapiens		 21.3							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055512	378152425							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680868	CN(C)C(=O)C(=O)c1ccccc1Nc1nc(Nc2ccc3OCCN(C(=O)C=C)c3c2)ncc1Cl	InChI=1S/C25H23ClN6O4/c1-4-21(33)32-11-12-36-20-10-9-15(13-19(20)32)28-25-27-14-17(26)23(30-25)29-18-8-6-5-7-16(18)22(34)24(35)31(2)3/h4-10,13-14H,1,11-12H2,2-3H3,(H2,27,28,29,30)	KXPICMSXZCNILY-UHFFFAOYSA-N	270542	2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] oxazin-6-ylamino)-5- chloropyrimidin-4- ylamino)phenyl)-N,N- dimethyl-2-oxoacetamide::US10059688, Example 87::US9783524, Example 87	Epidermal growth factor receptor	Homo sapiens		 354							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			87055512	378152425							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680872	CN(C)CCOc1ccc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)cc1NC(=O)C=C	InChI=1S/C27H30ClN7O4/c1-6-23(36)31-21-15-17(11-12-22(21)39-14-13-34(2)3)30-27-29-16-19(28)25(33-27)32-20-10-8-7-9-18(20)24(37)26(38)35(4)5/h6-12,15-16H,1,13-14H2,2-5H3,(H,31,36)(H2,29,30,32,33)	WSDSYYCVRCLNSN-UHFFFAOYSA-N	270543	US10059688, Example 115::US9783524, Example 115	Epidermal growth factor receptor	Homo sapiens		 18.7							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270543&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117811098	378152426							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680873	CN(C)CCOc1ccc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)cc1NC(=O)C=C	InChI=1S/C27H30ClN7O4/c1-6-23(36)31-21-15-17(11-12-22(21)39-14-13-34(2)3)30-27-29-16-19(28)25(33-27)32-20-10-8-7-9-18(20)24(37)26(38)35(4)5/h6-12,15-16H,1,13-14H2,2-5H3,(H,31,36)(H2,29,30,32,33)	WSDSYYCVRCLNSN-UHFFFAOYSA-N	270543	US10059688, Example 115::US9783524, Example 115	Epidermal growth factor receptor	Homo sapiens		 397							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270543&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117811098	378152426							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680877	COc1cc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)ccc1N1CCC(CC1)N(C)C	InChI=1S/C28H34ClN7O3/c1-34(2)19-12-14-36(15-13-19)23-11-10-18(16-24(23)39-5)31-28-30-17-21(29)26(33-28)32-22-9-7-6-8-20(22)25(37)27(38)35(3)4/h6-11,16-17,19H,12-15H2,1-5H3,(H2,30,31,32,33)	XYNBROWABUHURG-UHFFFAOYSA-N	270544	2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- 1-yl)-3-methoxyphenylamino) pyrimidin-4-ylamino)phenyl)- N,N-dimethyl-2-oxoacetamide::US10059688, Example 118::US9783524, Example 118	Epidermal growth factor receptor	Homo sapiens		 4.92							US Patent		10.7270/Q2WS8WCB		aid1797254	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117800589	378152427							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
680878	COc1cc(Nc2ncc(Cl)c(Nc3ccccc3C(=O)C(=O)N(C)C)n2)ccc1N1CCC(CC1)N(C)C	InChI=1S/C28H34ClN7O3/c1-34(2)19-12-14-36(15-13-19)23-11-10-18(16-24(23)39-5)31-28-30-17-21(29)26(33-28)32-22-9-7-6-8-20(22)25(37)27(38)35(3)4/h6-11,16-17,19H,12-15H2,1-5H3,(H2,30,31,32,33)	XYNBROWABUHURG-UHFFFAOYSA-N	270544	2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- 1-yl)-3-methoxyphenylamino) pyrimidin-4-ylamino)phenyl)- N,N-dimethyl-2-oxoacetamide::US10059688, Example 118::US9783524, Example 118	Epidermal growth factor receptor	Homo sapiens		 77.6							US Patent		10.7270/Q2WS8WCB		aid1797253	US9783524	Hu, S; Liu, X; Bai, J; Long, W	10/10/2017	8/19/2019	Betta Pharmaceuticals Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=270544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=270544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			117800589	378152427							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694061	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)C(C)C	InChI=1S/C26H29Cl2FN4O2/c1-14(2)33-10-16-6-15(7-17(16)11-33)12-35-23-9-21-18(8-22(23)34-3)26(31-13-30-21)32-20-5-4-19(27)24(28)25(20)29/h4-5,8-9,13-17H,6-7,10-12H2,1-3H3,(H,30,31,32)/t15-,16-,17+	UKKBXHWKVGSVEV-OSYLJGHBSA-N	351281	N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5r,6aS)-2-(1- methylethyl)octahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 1	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351281&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10369374	386053006							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694067	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(CC(C)C)C[C@H]2C1	InChI=1S/C27H31Cl2FN4O2/c1-15(2)10-34-11-17-6-16(7-18(17)12-34)13-36-24-9-22-19(8-23(24)35-3)27(32-14-31-22)33-21-5-4-20(28)25(29)26(21)30/h4-5,8-9,14-18H,6-7,10-13H2,1-3H3,(H,31,32,33)/t16-,17-,18+	RFKWUHOHGOAWTQ-NNZMDNLPSA-N	351282	N-(3,4-dichloro-2-fluorophenyl)-6- (methyloxy)-7-({[(3aR,5r,6aS)-2-(2- methylpropyl)octahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 8	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351282&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10369818	386053007							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694073	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	HVXKQKFEHMGHSL-QDMKHBRRSA-N	351283	N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 9	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351283&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10458325	386053008							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694079	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25BrClFN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	NPSLABWCQNFJHJ-QDMKHBRRSA-N	351284	N-(4-bromo-3-chloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 10	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351284&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10256639	386053009							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694085	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25ClF2N4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(26)22(25)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	KDAFZLQNEAKVCC-QDMKHBRRSA-N	351285	N-(3-chloro-2,4-difluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 11	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351285&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10073622	386053010							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694091	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-3-13(4-15(14)10-31)11-33-23-8-20-16(5-22(23)32-2)24(29-12-28-20)30-21-7-18(26)17(25)6-19(21)27/h5-8,12-15H,3-4,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	URLSAFHMCNOLOZ-QDMKHBRRSA-N	351286	N-(4,5-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 12	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351286&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10458326	386053011							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694097	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25BrClFN4O2/c1-31-9-14-3-13(4-15(14)10-31)11-33-23-8-20-16(5-22(23)32-2)24(29-12-28-20)30-21-7-18(26)17(25)6-19(21)27/h5-8,12-15H,3-4,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	QHXZJCIGDNUSOB-QDMKHBRRSA-N	351287	N-(4-bromo-5-chloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 13	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351287&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347091	386053012							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694103	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25BrCl2N4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	BLBVISQGOQQTND-QDMKHBRRSA-N	351288	N-(4-bromo-2,3-dichlorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 14	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351288&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10392846	386053013							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694109	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H26Cl2N4O2/c1-30-10-15-5-14(6-16(15)11-30)12-32-23-9-21-18(8-22(23)31-2)24(28-13-27-21)29-17-3-4-19(25)20(26)7-17/h3-4,7-9,13-16H,5-6,10-12H2,1-2H3,(H,27,28,29)/t14-,15+,16-	XJAYAHAZZKYCJC-MUJYYYPQSA-N	351289	N-(3,4-dichlorophenyl)-7-({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 15	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351289&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10073562	386053014							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694115	CCN1C[C@@H]2C[C@H](COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5F)c4cc3OC)C[C@@H]2C1	InChI=1S/C25H27BrClFN4O2/c1-3-32-10-15-6-14(7-16(15)11-32)12-34-22-9-20-17(8-21(22)33-2)25(30-13-29-20)31-19-5-4-18(26)23(27)24(19)28/h4-5,8-9,13-16H,3,6-7,10-12H2,1-2H3,(H,29,30,31)/t14-,15-,16+	VEIQGMIXACRMMO-PHZGNYQRSA-N	351290	N-(4-bromo-3-chloro-2-fluorophenyl)-7- ({[(3aR,5r,6aS)-2- ethyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 16	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351290&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9985010	386053015							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694121	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(CC(C)C)C[C@H]2C1	InChI=1S/C27H31BrClFN4O2/c1-15(2)10-34-11-17-6-16(7-18(17)12-34)13-36-24-9-22-19(8-23(24)35-3)27(32-14-31-22)33-21-5-4-20(28)25(29)26(21)30/h4-5,8-9,14-18H,6-7,10-13H2,1-3H3,(H,31,32,33)/t16-,17-,18+	WQHZIFFISAIJEF-NNZMDNLPSA-N	351291	N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)-7-({[(3aR,5r,6aS)-2-(2- methylpropyl)octahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 17	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351291&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10393395	386053016							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694127	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrCl2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	QPNYAXXXUXFKDG-ARLHGKGLSA-N	351292	N-(4-bromo-2,3-dichlorophenyl)-7- {[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 18	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351292&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946765	386053017							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694133	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	KHSJGHHCLKKKKU-ARLHGKGLSA-N	351293	N-(4,5-dichloro-2-fluorophenyl)-7-{[(3R,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 19	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351293&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70795120	386053018							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694139	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	NJQIBYWJBXKSRO-ARLHGKGLSA-N	351294	N-(4-bromo-5-chloro-2-fluorophenyl)-7- {[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 20	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946714	386053019							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694145	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23ClF2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(25)21(24)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	IFVXCNKRSUKURE-ARLHGKGLSA-N	351295	N-(3-chloro-2,4-difluorophenyl)-7-{[(3R,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 21	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351295&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946733	386053020							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694151	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	ABXIBRWZRWHJCZ-KZUDCZAMSA-N	351296	N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 22	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351296&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802840	386053021							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694157	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	CMTRUERFSJKMJQ-KZUDCZAMSA-N	351297	N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 23	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351297&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802617	386053022							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694163	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23ClF2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(25)21(24)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	IFVXCNKRSUKURE-KZUDCZAMSA-N	351298	N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 24	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351298&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802554	386053023							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694169	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN2CCOCC2CO1	InChI=1S/C23H24Cl2N4O4/c1-30-21-7-17-20(26-13-27-23(17)28-14-2-3-18(24)19(25)6-14)8-22(21)33-12-16-9-29-4-5-31-10-15(29)11-32-16/h2-3,6-8,13,15-16H,4-5,9-12H2,1H3,(H,26,27,28)	ZJFHLSCSEWIASA-UHFFFAOYSA-N	351299	N-(3,4-dichlorophenyl)-7-[(hexahydro-1H- [1,4]oxazino[3,4-c][1,4]oxazin-3- ylmethyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 25	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351299&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58013804	386053024							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694175	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	KHSJGHHCLKKKKU-KZUDCZAMSA-N	351300	N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 26	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802705	386053025							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694181	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrCl2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	QPNYAXXXUXFKDG-KZUDCZAMSA-N	351301	N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 27	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351301&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802649	386053026							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694187	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	NJQIBYWJBXKSRO-KZUDCZAMSA-N	351302	N-(4-bromo-5-chloro-2-fluorophenyl)-7- {[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 28	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351302&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802768	386053027							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694193	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	ABXIBRWZRWHJCZ-ARLHGKGLSA-N	351303	N-(3,4-dichloro-2-fluorophenyl)-7-{[(3R,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 29	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351303&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946716	386053028							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694199	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	CMTRUERFSJKMJQ-ARLHGKGLSA-N	351304	N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 30	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351304&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70795293	386053029							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694205	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@H]1CN2CCC[C@@H]2CO1	InChI=1S/C23H23BrClFN4O3/c1-31-21-5-15-19(8-22(21)33-11-14-9-30-4-2-3-13(30)10-32-14)27-12-28-23(15)29-20-7-17(25)16(24)6-18(20)26/h5-8,12-14H,2-4,9-11H2,1H3,(H,27,28,29)/t13-,14-/m1/s1	NGRFKPHUUUCTAT-ZIAGYGMSSA-N	351305	N-(4-bromo-5-chloro-2-fluorophenyl)-7- {[(3S,8aS)-hexahydro-1H-pyrrolo[2,1- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 32	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351305&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70795231	386053030							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694211	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23Cl2FN4O3/c1-31-19-7-15-18(8-20(19)33-11-14-9-30-6-2-3-13(30)10-32-14)27-12-28-23(15)29-17-5-4-16(24)21(25)22(17)26/h4-5,7-8,12-14H,2-3,6,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	REMMHMJADZNMGO-KBPBESRZSA-N	351306	N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 36	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351306&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802793	386053031							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694217	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23ClF2N4O3/c1-31-19-7-15-18(8-20(19)33-11-14-9-30-6-2-3-13(30)10-32-14)27-12-28-23(15)29-17-5-4-16(25)21(24)22(17)26/h4-5,7-8,12-14H,2-3,6,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	AFHNMWQBLLGGSP-KBPBESRZSA-N	351307	N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 38	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351307&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58013819	386053032							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694223	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23BrCl2N4O3/c1-31-19-7-15-18(8-20(19)33-11-14-9-30-6-2-3-13(30)10-32-14)27-12-28-23(15)29-17-5-4-16(24)21(25)22(17)26/h4-5,7-8,12-14H,2-3,6,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	LTXUQGNDYGUYMC-KBPBESRZSA-N	351308	N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 39	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351308&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802722	386053033							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694229	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23Cl2FN4O3/c1-31-21-5-15-19(8-22(21)33-11-14-9-30-4-2-3-13(30)10-32-14)27-12-28-23(15)29-20-7-17(25)16(24)6-18(20)26/h5-8,12-14H,2-4,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	YTGFCYJRAIFFGH-KBPBESRZSA-N	351309	N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 40	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630919	386053034							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694235	CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5cc(Cl)c(Br)cc5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22BrClFN3O5/c1-30-18-3-12-16(27-10-28-23(12)29-17-5-14(25)13(24)4-15(17)26)6-19(18)32-7-11-8-33-22-20(31-2)9-34-21(11)22/h3-6,10-11,20-22H,7-9H2,1-2H3,(H,27,28,29)/t11?,20-,21+,22+/m0/s1	ZFGGQFYLMRFDEB-QOPSNYKOSA-N	351310	1,4:3,6-dianhydro-5-({[4-[(4-bromo-5-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-xylo-hexitol::US9796704, Entry 41	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351310&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802812	386053035							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694241	CO[C@H]1CO[C@@H]2[C@H](COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)CO[C@H]12	InChI=1S/C23H23Cl2N3O5/c1-29-18-6-14-17(26-11-27-23(14)28-13-3-4-15(24)16(25)5-13)7-19(18)31-8-12-9-32-22-20(30-2)10-33-21(12)22/h3-7,11-12,20-22H,8-10H2,1-2H3,(H,26,27,28)/t12-,20+,21-,22-/m1/s1	VENHPOQTVRCHJV-JXBRRONGSA-N	351311	1,4:3,6-dianhydro-5-deoxy-5-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-glucitol::US9796704, Entry 42	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351311&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66955051	386053036							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694247	CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22Cl2FN3O5/c1-30-16-5-12-15(27-10-28-23(12)29-14-4-3-13(24)19(25)20(14)26)6-17(16)32-7-11-8-33-22-18(31-2)9-34-21(11)22/h3-6,10-11,18,21-22H,7-9H2,1-2H3,(H,27,28,29)/t11?,18-,21+,22+/m0/s1	XUCWVTDFYWWXFG-DIUUEDGKSA-N	351312	1,4:3,6-dianhydro-5-deoxy-5-({[4-[(3,4- dichloro-2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-xylo-hexitol::US9796704, Entry 43	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802681	386053037							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694253	CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22BrClFN3O5/c1-30-16-5-12-15(27-10-28-23(12)29-14-4-3-13(24)19(25)20(14)26)6-17(16)32-7-11-8-33-22-18(31-2)9-34-21(11)22/h3-6,10-11,18,21-22H,7-9H2,1-2H3,(H,27,28,29)/t11?,18-,21+,22+/m0/s1	FIJYWRPWHKFPLQ-DIUUEDGKSA-N	351313	1,4:3,6-dianhydro-5-({[4-[(4-bromo-3-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-xylo-hexitol::US9796704, Entry 44	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351313&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802690	386053038							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694259	CO[C@H]1CO[C@@H]2[C@H](COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5Cl)c4cc3OC)CO[C@H]12	InChI=1S/C23H22BrCl2N3O5/c1-30-16-5-12-15(27-10-28-23(12)29-14-4-3-13(24)19(25)20(14)26)6-17(16)32-7-11-8-33-22-18(31-2)9-34-21(11)22/h3-6,10-11,18,21-22H,7-9H2,1-2H3,(H,27,28,29)/t11-,18+,21-,22-/m1/s1	QTWKCJAINLFWKV-ZMQOCNJZSA-N	351314	1,4:3,6-dianhydro-5-({[4-[(4-bromo-2,3- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-glucitol::US9796704, Entry 46	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351314&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66954887	386053039							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694265	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCCC[C@H]2C(=O)N1	InChI=1S/C24H24Cl2FN5O3/c1-34-19-8-14-17(28-12-29-23(14)31-16-6-5-15(25)21(26)22(16)27)9-20(19)35-11-13-10-32-7-3-2-4-18(32)24(33)30-13/h5-6,8-9,12-13,18H,2-4,7,10-11H2,1H3,(H,30,33)(H,28,29,31)/t13-,18-/m0/s1	ZDTMGSSRQLKYTK-UGSOOPFHSA-N	351315	(3S,9aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydro-2H-pyrido[1,2- a]pyrazin-1(6H)-one::US9796704, Entry 49	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351315&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802612	386053040							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694271	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1	InChI=1S/C23H22Cl2FN5O3/c1-33-18-7-13-16(27-11-28-22(13)30-15-5-4-14(24)20(25)21(15)26)8-19(18)34-10-12-9-31-6-2-3-17(31)23(32)29-12/h4-5,7-8,11-12,17H,2-3,6,9-10H2,1H3,(H,29,32)(H,27,28,30)/t12-,17-/m0/s1	VXJCKEGWFQFYGD-SJCJKPOMSA-N	351316	(3S,8aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one::US9796704, Entry 51	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351316&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630923	386053041							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694277	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@@H]2C(=O)N1	InChI=1S/C23H22Cl2FN5O3/c1-33-18-7-13-16(27-11-28-22(13)30-15-5-4-14(24)20(25)21(15)26)8-19(18)34-10-12-9-31-6-2-3-17(31)23(32)29-12/h4-5,7-8,11-12,17H,2-3,6,9-10H2,1H3,(H,29,32)(H,27,28,30)/t12-,17+/m0/s1	VXJCKEGWFQFYGD-YVEFUNNKSA-N	351317	(3S,8aR)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one::US9796704, Entry 52	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351317&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630924	386053042							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694283	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1	InChI=1S/C23H22BrClFN5O3/c1-33-18-7-13-16(27-11-28-22(13)30-15-5-4-14(24)20(25)21(15)26)8-19(18)34-10-12-9-31-6-2-3-17(31)23(32)29-12/h4-5,7-8,11-12,17H,2-3,6,9-10H2,1H3,(H,29,32)(H,27,28,30)/t12-,17-/m0/s1	OEGXYNWEJSFYPO-SJCJKPOMSA-N	351318	(3S,8aS)-3-({[4-[(4-bromo-3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one::US9796704, Entry 53	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351318&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802807	386053043							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694289	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCC[C@@H]2C(=O)N1C	InChI=1S/C24H24Cl2FN5O3/c1-31-13(10-32-7-3-4-18(32)24(31)33)11-35-20-9-17-14(8-19(20)34-2)23(29-12-28-17)30-16-6-5-15(25)21(26)22(16)27/h5-6,8-9,12-13,18H,3-4,7,10-11H2,1-2H3,(H,28,29,30)/t13-,18-/m1/s1	RPLCLUCJTHAIOW-FZKQIMNGSA-N	351319	(3S,8aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)-2- methylhexahydropyrrolo[1,2-a]pyrazin-1(2H)- one::US9796704, Entry 54	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351319&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10436695	386053044							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694294	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCNC1CC2CCC(C1)N2C	InChI=1S/C25H29Cl2N5O2/c1-32-17-4-5-18(32)10-16(9-17)28-7-8-34-24-13-22-19(12-23(24)33-2)25(30-14-29-22)31-15-3-6-20(26)21(27)11-15/h3,6,11-14,16-18,28H,4-5,7-10H2,1-2H3,(H,29,30,31)	BKBIBLPFCFCOQQ-UHFFFAOYSA-N	351320	N-(3,4-dichlorophenyl)-7-({2-[(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)amino]ethyl}oxy)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 55	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351320	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351320&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10413710	386053045							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694300	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN2CSC[C@H]2CO1	InChI=1S/C22H22Cl2N4O3S/c1-29-20-5-16-19(25-11-26-22(16)27-13-2-3-17(23)18(24)4-13)6-21(20)31-9-15-7-28-12-32-10-14(28)8-30-15/h2-6,11,14-15H,7-10,12H2,1H3,(H,25,26,27)/t14-,15?/m1/s1	RFGYFZFUMBQSCW-GICMACPYSA-N	351321	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- {[(8aR)-tetrahydro-1H-[1,3]thiazolo[4,3- c][1,4]oxazin-6-ylmethyl]oxy}quinazolin-4- amine::US9796704, Entry 56	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351321&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802698	386053046							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694306	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CC2CCC(C1)N2C	InChI=1S/C25H28Cl2N4O2/c1-31-17-4-5-18(31)10-15(9-17)7-8-33-24-13-22-19(12-23(24)32-2)25(29-14-28-22)30-16-3-6-20(26)21(27)11-16/h3,6,11-15,17-18H,4-5,7-10H2,1-2H3,(H,28,29,30)	KLDWSPPOKXJTIT-UHFFFAOYSA-N	351322	N-(3,4-dichlorophenyl)-7-{[2-(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)ethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 57	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351322&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10480595	386053047							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694312	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CC2CCC(C1)N2C	InChI=1S/C24H26Cl2N4O2/c1-30-16-4-5-17(30)8-14(7-16)12-32-23-11-21-18(10-22(23)31-2)24(28-13-27-21)29-15-3-6-19(25)20(26)9-15/h3,6,9-11,13-14,16-17H,4-5,7-8,12H2,1-2H3,(H,27,28,29)	UAHJYZIKOGTHIW-UHFFFAOYSA-N	351323	N-(3,4-dichlorophenyl)-7-{[(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 58	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351323&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10005056	386053048							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694318	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C23H24Cl2N4O2/c1-29-10-13-5-16(6-14(13)11-29)31-22-9-20-17(8-21(22)30-2)23(27-12-26-20)28-15-3-4-18(24)19(25)7-15/h3-4,7-9,12-14,16H,5-6,10-11H2,1-2H3,(H,26,27,28)/t13-,14+,16?	DVEHRUCQBHJWFA-MZBDJJRSSA-N	351324	N-(3,4-dichlorophenyl)-7-{[(3aR,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]oxy}-6-(methyloxy)quinazolin-4-amine::US9796704, Entry 59	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351324&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10253661	386053049							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694324	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1CC2CCC(C1)N2C	InChI=1S/C23H24Cl2N4O2/c1-29-14-4-5-15(29)9-16(8-14)31-22-11-20-17(10-21(22)30-2)23(27-12-26-20)28-13-3-6-18(24)19(25)7-13/h3,6-7,10-12,14-16H,4-5,8-9H2,1-2H3,(H,26,27,28)	AXFITPBCUMOSEI-UHFFFAOYSA-N	351325	N-(3,4-dichlorophenyl)-7-[(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)oxy]-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 60	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351325&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10321951	386053050							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694330	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3cc(Cl)c(Br)cc3F)c2cc1OC	InChI=1S/C22H20BrClFN3O5/c1-29-16-3-10-14(6-17(16)33-19-8-32-20-18(30-2)7-31-21(19)20)26-9-27-22(10)28-15-5-12(24)11(23)4-13(15)25/h3-6,9,18-21H,7-8H2,1-2H3,(H,26,27,28)/t18-,19-,20+,21+/m0/s1	UUILILXZMGYNLD-UWHLTILDSA-N	351326	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 61	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351326&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10325018	386053051							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694336	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC	InChI=1S/C22H20Cl2FN3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	KURAWEFNNHDHOM-ZCLUNYJNSA-N	351327	1,4:3,6-dianhydro-2-O-[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-5-O-methyl-L-iditol::US9796704, Entry 62	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351327&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10480937	386053052							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694342	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1OC	InChI=1S/C22H20BrClFN3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	BVPDJKPURONCRY-ZCLUNYJNSA-N	351328	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 63	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351328&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10392528	386053053							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694348	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3Cl)c2cc1OC	InChI=1S/C22H20Cl3N3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	IOXJGKZLPLFOBF-ZCLUNYJNSA-N	351329	1,4:3,6-dianhydro-2-O-methyl-5-O-{6- (methyloxy)-4-[(2,3,4- trichlorophenyl)amino]quinazolin-7-yl}-L-iditol::US9796704, Entry 64	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351329&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10369165	386053054							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694354	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3)c2cc1OC	InChI=1S/C22H21Cl2N3O5/c1-28-16-6-12-15(25-10-26-22(12)27-11-3-4-13(23)14(24)5-11)7-17(16)32-19-9-31-20-18(29-2)8-30-21(19)20/h3-7,10,18-21H,8-9H2,1-2H3,(H,25,26,27)/t18-,19-,20+,21+/m0/s1	ZAMYFBONNUIDDG-UWHLTILDSA-N	351330	1,4:3,6-dianhydro-5-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-O-methyl-D- xylo-hexitol::US9796704, Entry 65::US9796704, Entry 72	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351330&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10412767	386053055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694360	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3Cl)c2cc1OC	InChI=1S/C22H20BrCl2N3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	ZLFBWBUGVAULCA-ZCLUNYJNSA-N	351331	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-2,3- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 66	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351331&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347695	386053056							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694366	COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OCC21OCCO1	InChI=1S/C23H21BrClN3O6/c1-29-17-7-13-16(26-11-27-22(13)28-12-2-3-14(24)15(25)6-12)8-18(17)34-19-9-30-21-20(19)31-10-23(21)32-4-5-33-23/h2-3,6-8,11,19-21H,4-5,9-10H2,1H3,(H,26,27,28)/t19-,20+,21-/m0/s1	ZDOPWPQLWDULEV-HBMCJLEFSA-N	351332	US9796704, Entry 67::dianhydro-5-O-[4-[(4-bromo-3- chlorophenyl)amino]-6-(methyloxy)- quinazolin-7-yl]-L-sorbose ethylene glycol acetal	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351332&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10482693	386053057							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694372	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3F)c2cc1OC	InChI=1S/C22H20ClF2N3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(24)18(23)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	SJEYKCLWHCAMQL-ZCLUNYJNSA-N	351333	1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2,4- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 68	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351333&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10390394	386053058							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694398	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)C(C)C	InChI=1S/C26H29Cl2FN4O2/c1-14(2)33-10-16-6-15(7-17(16)11-33)12-35-23-9-21-18(8-22(23)34-3)26(31-13-30-21)32-20-5-4-19(27)24(28)25(20)29/h4-5,8-9,13-17H,6-7,10-12H2,1-3H3,(H,30,31,32)/t15-,16-,17+	UKKBXHWKVGSVEV-OSYLJGHBSA-N	351281	N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5r,6aS)-2-(1- methylethyl)octahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 1	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351281&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10369374	386053006							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694405	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)C(C)=O	InChI=1S/C25H25BrClFN4O3/c1-13(33)32-9-15-5-14(6-16(15)10-32)11-35-22-8-20-17(7-21(22)34-2)25(30-12-29-20)31-19-4-3-18(26)23(27)24(19)28/h3-4,7-8,12,14-16H,5-6,9-11H2,1-2H3,(H,29,30,31)/t14-,15-,16+	SPUVKXRMQZAIAZ-PHZGNYQRSA-N	351335	7-({[(3aR,5r,6aS)-2- acetyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-N-(4-bromo-3-chloro-2- fluorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 3	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351335&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10076584	386053060							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694410	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@@H]2CNC[C@@H]2C1	InChI=1S/C23H23BrClFN4O2/c1-31-19-6-15-18(7-20(19)32-10-12-4-13-8-27-9-14(13)5-12)28-11-29-23(15)30-17-3-2-16(24)21(25)22(17)26/h2-3,6-7,11-14,27H,4-5,8-10H2,1H3,(H,28,29,30)/t12-,13-,14+	ZNKFCCNXFVRXHC-ZSOGYDGISA-N	351336	N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)-7-{[(3aR,5r,6aS)- octahydrocyclopenta[c]pyrrol-5- ylmethyl]oxy}quinazolin-4-amine::US9796704, Entry 4	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9984215	386053061							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694414	CCOC(=O)N1C[C@@H]2CC(COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5F)c4cc3OC)C[C@@H]2C1	InChI=1S/C26H27BrClFN4O4/c1-3-36-26(34)33-10-15-6-14(7-16(15)11-33)12-37-22-9-20-17(8-21(22)35-2)25(31-13-30-20)32-19-5-4-18(27)23(28)24(19)29/h4-5,8-9,13-16H,3,6-7,10-12H2,1-2H3,(H,30,31,32)/t14?,15-,16+	PLTBBZBWBKAMPZ-MQVJKMGUSA-N	351337	US9796704, Entry 5::ethyl (3aR,6aS)-5-({[4-[(4-bromo-3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7- yl]oxy}methyl)hexahydrocyclopenta[c]pyrrole- 2(1H)-carboxylate	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351337&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10031389	386053062							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694418	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)S(C)(=O)=O	InChI=1S/C24H25BrClFN4O4S/c1-34-20-7-16-19(28-12-29-24(16)30-18-4-3-17(25)22(26)23(18)27)8-21(20)35-11-13-5-14-9-31(36(2,32)33)10-15(14)6-13/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14-,15+	DYYJQOFBFXWRDD-QKDCVEJESA-N	351338	N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)-7-({[(3aR,5r,6aS)-2- (methylsulfonyl)octahydrocyclopenta[c]pyrrol- 5-yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 6	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351338&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9986023	386053063							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694423	CCN1C[C@@H]2C[C@H](COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5F)c4cc3OC)C[C@@H]2C1	InChI=1S/C25H27Cl2FN4O2/c1-3-32-10-15-6-14(7-16(15)11-32)12-34-22-9-20-17(8-21(22)33-2)25(30-13-29-20)31-19-5-4-18(26)23(27)24(19)28/h4-5,8-9,13-16H,3,6-7,10-12H2,1-2H3,(H,29,30,31)/t14-,15-,16+	QHBIMTBQLBHDHJ-PHZGNYQRSA-N	351339	N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5r,6aS)-2- ethyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 7	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351339&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11755883	386053064							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694427	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(CC(C)C)C[C@H]2C1	InChI=1S/C27H31Cl2FN4O2/c1-15(2)10-34-11-17-6-16(7-18(17)12-34)13-36-24-9-22-19(8-23(24)35-3)27(32-14-31-22)33-21-5-4-20(28)25(29)26(21)30/h4-5,8-9,14-18H,6-7,10-13H2,1-3H3,(H,31,32,33)/t16-,17-,18+	RFKWUHOHGOAWTQ-NNZMDNLPSA-N	351282	N-(3,4-dichloro-2-fluorophenyl)-6- (methyloxy)-7-({[(3aR,5r,6aS)-2-(2- methylpropyl)octahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 8	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351282&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10369818	386053007							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694431	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	HVXKQKFEHMGHSL-QDMKHBRRSA-N	351283	N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 9	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351283&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10458325	386053008							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694435	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25BrClFN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	NPSLABWCQNFJHJ-QDMKHBRRSA-N	351284	N-(4-bromo-3-chloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 10	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351284&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10256639	386053009							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694439	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25ClF2N4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(26)22(25)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	KDAFZLQNEAKVCC-QDMKHBRRSA-N	351285	N-(3-chloro-2,4-difluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 11	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351285&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10073622	386053010							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694443	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-3-13(4-15(14)10-31)11-33-23-8-20-16(5-22(23)32-2)24(29-12-28-20)30-21-7-18(26)17(25)6-19(21)27/h5-8,12-15H,3-4,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	URLSAFHMCNOLOZ-QDMKHBRRSA-N	351286	N-(4,5-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 12	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351286&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10458326	386053011							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694447	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25BrClFN4O2/c1-31-9-14-3-13(4-15(14)10-31)11-33-23-8-20-16(5-22(23)32-2)24(29-12-28-20)30-21-7-18(26)17(25)6-19(21)27/h5-8,12-15H,3-4,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	QHXZJCIGDNUSOB-QDMKHBRRSA-N	351287	N-(4-bromo-5-chloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 13	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351287&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347091	386053012							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694451	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H25BrCl2N4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-	BLBVISQGOQQTND-QDMKHBRRSA-N	351288	N-(4-bromo-2,3-dichlorophenyl)-7- ({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 14	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351288&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10392846	386053013							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694455	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C24H26Cl2N4O2/c1-30-10-15-5-14(6-16(15)11-30)12-32-23-9-21-18(8-22(23)31-2)24(28-13-27-21)29-17-3-4-19(25)20(26)7-17/h3-4,7-9,13-16H,5-6,10-12H2,1-2H3,(H,27,28,29)/t14-,15+,16-	XJAYAHAZZKYCJC-MUJYYYPQSA-N	351289	N-(3,4-dichlorophenyl)-7-({[(3aR,5s,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 15	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351289&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10073562	386053014							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694459	CCN1C[C@@H]2C[C@H](COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5F)c4cc3OC)C[C@@H]2C1	InChI=1S/C25H27BrClFN4O2/c1-3-32-10-15-6-14(7-16(15)11-32)12-34-22-9-20-17(8-21(22)33-2)25(30-13-29-20)31-19-5-4-18(26)23(27)24(19)28/h4-5,8-9,13-16H,3,6-7,10-12H2,1-2H3,(H,29,30,31)/t14-,15-,16+	VEIQGMIXACRMMO-PHZGNYQRSA-N	351290	N-(4-bromo-3-chloro-2-fluorophenyl)-7- ({[(3aR,5r,6aS)-2- ethyloctahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 16	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351290&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9985010	386053015							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694463	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(CC(C)C)C[C@H]2C1	InChI=1S/C27H31BrClFN4O2/c1-15(2)10-34-11-17-6-16(7-18(17)12-34)13-36-24-9-22-19(8-23(24)35-3)27(32-14-31-22)33-21-5-4-20(28)25(29)26(21)30/h4-5,8-9,14-18H,6-7,10-13H2,1-3H3,(H,31,32,33)/t16-,17-,18+	WQHZIFFISAIJEF-NNZMDNLPSA-N	351291	N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)-7-({[(3aR,5r,6aS)-2-(2- methylpropyl)octahydrocyclopenta[c]pyrrol-5- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 17	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351291&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10393395	386053016							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694467	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrCl2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	QPNYAXXXUXFKDG-ARLHGKGLSA-N	351292	N-(4-bromo-2,3-dichlorophenyl)-7- {[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 18	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351292&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946765	386053017							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694471	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	KHSJGHHCLKKKKU-ARLHGKGLSA-N	351293	N-(4,5-dichloro-2-fluorophenyl)-7-{[(3R,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 19	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351293&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70795120	386053018							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694475	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	NJQIBYWJBXKSRO-ARLHGKGLSA-N	351294	N-(4-bromo-5-chloro-2-fluorophenyl)-7- {[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 20	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946714	386053019							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694479	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23ClF2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(25)21(24)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	IFVXCNKRSUKURE-ARLHGKGLSA-N	351295	N-(3-chloro-2,4-difluorophenyl)-7-{[(3R,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 21	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351295&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946733	386053020							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694484	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	ABXIBRWZRWHJCZ-KZUDCZAMSA-N	351296	N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 22	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351296&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802840	386053021							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694488	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	CMTRUERFSJKMJQ-KZUDCZAMSA-N	351297	N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 23	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351297&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802617	386053022							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694492	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23ClF2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(25)21(24)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	IFVXCNKRSUKURE-KZUDCZAMSA-N	351298	N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 24	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351298&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802554	386053023							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694494	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN2CCOCC2CO1	InChI=1S/C23H24Cl2N4O4/c1-30-21-7-17-20(26-13-27-23(17)28-14-2-3-18(24)19(25)6-14)8-22(21)33-12-16-9-29-4-5-31-10-15(29)11-32-16/h2-3,6-8,13,15-16H,4-5,9-12H2,1H3,(H,26,27,28)	ZJFHLSCSEWIASA-UHFFFAOYSA-N	351299	N-(3,4-dichlorophenyl)-7-[(hexahydro-1H- [1,4]oxazino[3,4-c][1,4]oxazin-3- ylmethyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 25	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351299&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58013804	386053024							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694498	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	KHSJGHHCLKKKKU-KZUDCZAMSA-N	351300	N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 26	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351300&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802705	386053025							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694502	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrCl2N4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	QPNYAXXXUXFKDG-KZUDCZAMSA-N	351301	N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 27	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351301&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802649	386053026							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694506	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-21-4-15-19(27-12-28-23(15)29-20-6-17(25)16(24)5-18(20)26)7-22(21)34-11-14-8-30-2-3-32-9-13(30)10-33-14/h4-7,12-14H,2-3,8-11H2,1H3,(H,27,28,29)/t13?,14-/m0/s1	NJQIBYWJBXKSRO-KZUDCZAMSA-N	351302	N-(4-bromo-5-chloro-2-fluorophenyl)-7- {[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 28	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351302&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802768	386053027							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694510	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23Cl2FN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	ABXIBRWZRWHJCZ-ARLHGKGLSA-N	351303	N-(3,4-dichloro-2-fluorophenyl)-7-{[(3R,9aS)- hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin- 3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 29	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351303&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70946716	386053028							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694515	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1	InChI=1S/C23H23BrClFN4O4/c1-31-19-6-15-18(27-12-28-23(15)29-17-3-2-16(24)21(25)22(17)26)7-20(19)34-11-14-8-30-4-5-32-9-13(30)10-33-14/h2-3,6-7,12-14H,4-5,8-11H2,1H3,(H,27,28,29)/t13?,14-/m1/s1	CMTRUERFSJKMJQ-ARLHGKGLSA-N	351304	N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 30	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351304&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70795293	386053029							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694519	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@H]1CN2CCC[C@@H]2CO1	InChI=1S/C23H24Cl2N4O3/c1-30-21-8-17-20(26-13-27-23(17)28-14-4-5-18(24)19(25)7-14)9-22(21)32-12-16-10-29-6-2-3-15(29)11-31-16/h4-5,7-9,13,15-16H,2-3,6,10-12H2,1H3,(H,26,27,28)/t15-,16-/m1/s1	FSJDACURTSWGHC-HZPDHXFCSA-N	351340	N-(3,4-dichlorophenyl)-7-{[(3R,8aR)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 31	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802880	386053065							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694523	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@H]1CN2CCC[C@@H]2CO1	InChI=1S/C23H23BrClFN4O3/c1-31-21-5-15-19(8-22(21)33-11-14-9-30-4-2-3-13(30)10-32-14)27-12-28-23(15)29-20-7-17(25)16(24)6-18(20)26/h5-8,12-14H,2-4,9-11H2,1H3,(H,27,28,29)/t13-,14-/m1/s1	NGRFKPHUUUCTAT-ZIAGYGMSSA-N	351305	N-(4-bromo-5-chloro-2-fluorophenyl)-7- {[(3S,8aS)-hexahydro-1H-pyrrolo[2,1- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 32	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351305&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			70795231	386053030							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694527	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1CN2CCC[C@@H]2CO1	InChI=1S/C23H24Cl2N4O3/c1-30-21-8-17-20(26-13-27-23(17)28-14-4-5-18(24)19(25)7-14)9-22(21)32-12-16-10-29-6-2-3-15(29)11-31-16/h4-5,7-9,13,15-16H,2-3,6,10-12H2,1H3,(H,26,27,28)/t15-,16+/m1/s1	FSJDACURTSWGHC-CVEARBPZSA-N	351341	N-(3,4-dichlorophenyl)-7-{[(3S,8aR)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 33	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351341&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802582	386053066							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694532	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H24Cl2N4O3/c1-30-21-8-17-20(26-13-27-23(17)28-14-4-5-18(24)19(25)7-14)9-22(21)32-12-16-10-29-6-2-3-15(29)11-31-16/h4-5,7-9,13,15-16H,2-3,6,10-12H2,1H3,(H,26,27,28)/t15-,16-/m0/s1	FSJDACURTSWGHC-HOTGVXAUSA-N	351342	N-(3,4-dichlorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 34	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351342&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802678	386053067							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694537	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H24Cl2N4O3/c1-30-21-8-17-20(26-13-27-23(17)28-14-4-5-18(24)19(25)7-14)9-22(21)32-12-16-10-29-6-2-3-15(29)11-31-16/h4-5,7-9,13,15-16H,2-3,6,10-12H2,1H3,(H,26,27,28)/t15-,16+/m0/s1	FSJDACURTSWGHC-JKSUJKDBSA-N	351343	N-(3,4-dichlorophenyl)-7-{[(3R,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 35	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351343&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838546	386053068							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694542	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23Cl2FN4O3/c1-31-19-7-15-18(8-20(19)33-11-14-9-30-6-2-3-13(30)10-32-14)27-12-28-23(15)29-17-5-4-16(24)21(25)22(17)26/h4-5,7-8,12-14H,2-3,6,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	REMMHMJADZNMGO-KBPBESRZSA-N	351306	N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 36	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351306&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802793	386053031							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694546	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23BrClFN4O3/c1-31-19-7-15-18(8-20(19)33-11-14-9-30-6-2-3-13(30)10-32-14)27-12-28-23(15)29-17-5-4-16(24)21(25)22(17)26/h4-5,7-8,12-14H,2-3,6,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	VEZBREXQDQRJTD-KBPBESRZSA-N	351344	N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3S,8aS)-hexahydro-1H-pyrrolo[2,1- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 37	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351344&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802905	386053069							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694551	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23ClF2N4O3/c1-31-19-7-15-18(8-20(19)33-11-14-9-30-6-2-3-13(30)10-32-14)27-12-28-23(15)29-17-5-4-16(25)21(24)22(17)26/h4-5,7-8,12-14H,2-3,6,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	AFHNMWQBLLGGSP-KBPBESRZSA-N	351307	N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 38	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351307&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58013819	386053032							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694556	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23BrCl2N4O3/c1-31-19-7-15-18(8-20(19)33-11-14-9-30-6-2-3-13(30)10-32-14)27-12-28-23(15)29-17-5-4-16(24)21(25)22(17)26/h4-5,7-8,12-14H,2-3,6,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	LTXUQGNDYGUYMC-KBPBESRZSA-N	351308	N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 39	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351308&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802722	386053033							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694561	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1	InChI=1S/C23H23Cl2FN4O3/c1-31-21-5-15-19(8-22(21)33-11-14-9-30-4-2-3-13(30)10-32-14)27-12-28-23(15)29-20-7-17(25)16(24)6-18(20)26/h5-8,12-14H,2-4,9-11H2,1H3,(H,27,28,29)/t13-,14-/m0/s1	YTGFCYJRAIFFGH-KBPBESRZSA-N	351309	N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 40	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630919	386053034							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694565	CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5cc(Cl)c(Br)cc5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22BrClFN3O5/c1-30-18-3-12-16(27-10-28-23(12)29-17-5-14(25)13(24)4-15(17)26)6-19(18)32-7-11-8-33-22-20(31-2)9-34-21(11)22/h3-6,10-11,20-22H,7-9H2,1-2H3,(H,27,28,29)/t11?,20-,21+,22+/m0/s1	ZFGGQFYLMRFDEB-QOPSNYKOSA-N	351310	1,4:3,6-dianhydro-5-({[4-[(4-bromo-5-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-xylo-hexitol::US9796704, Entry 41	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351310&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802812	386053035							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694569	CO[C@H]1CO[C@@H]2[C@H](COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)CO[C@H]12	InChI=1S/C23H23Cl2N3O5/c1-29-18-6-14-17(26-11-27-23(14)28-13-3-4-15(24)16(25)5-13)7-19(18)31-8-12-9-32-22-20(30-2)10-33-21(12)22/h3-7,11-12,20-22H,8-10H2,1-2H3,(H,26,27,28)/t12-,20+,21-,22-/m1/s1	VENHPOQTVRCHJV-JXBRRONGSA-N	351311	1,4:3,6-dianhydro-5-deoxy-5-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-glucitol::US9796704, Entry 42	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351311&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66955051	386053036							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694573	CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22Cl2FN3O5/c1-30-16-5-12-15(27-10-28-23(12)29-14-4-3-13(24)19(25)20(14)26)6-17(16)32-7-11-8-33-22-18(31-2)9-34-21(11)22/h3-6,10-11,18,21-22H,7-9H2,1-2H3,(H,27,28,29)/t11?,18-,21+,22+/m0/s1	XUCWVTDFYWWXFG-DIUUEDGKSA-N	351312	1,4:3,6-dianhydro-5-deoxy-5-({[4-[(3,4- dichloro-2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-xylo-hexitol::US9796704, Entry 43	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802681	386053037							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694577	CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22BrClFN3O5/c1-30-16-5-12-15(27-10-28-23(12)29-14-4-3-13(24)19(25)20(14)26)6-17(16)32-7-11-8-33-22-18(31-2)9-34-21(11)22/h3-6,10-11,18,21-22H,7-9H2,1-2H3,(H,27,28,29)/t11?,18-,21+,22+/m0/s1	FIJYWRPWHKFPLQ-DIUUEDGKSA-N	351313	1,4:3,6-dianhydro-5-({[4-[(4-bromo-3-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-xylo-hexitol::US9796704, Entry 44	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351313&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802690	386053038							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694581	CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22ClF2N3O5/c1-30-16-5-12-15(27-10-28-23(12)29-14-4-3-13(25)19(24)20(14)26)6-17(16)32-7-11-8-33-22-18(31-2)9-34-21(11)22/h3-6,10-11,18,21-22H,7-9H2,1-2H3,(H,27,28,29)/t11?,18-,21+,22+/m0/s1	JRFNNCFUXZAXOL-DIUUEDGKSA-N	351345	1,4:3,6-dianhydro-5-({[4-[(3-chloro-2,4- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-xylo-hexitol::US9796704, Entry 45	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351345&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802686	386053070							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694585	CO[C@H]1CO[C@@H]2[C@H](COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5Cl)c4cc3OC)CO[C@H]12	InChI=1S/C23H22BrCl2N3O5/c1-30-16-5-12-15(27-10-28-23(12)29-14-4-3-13(24)19(25)20(14)26)6-17(16)32-7-11-8-33-22-18(31-2)9-34-21(11)22/h3-6,10-11,18,21-22H,7-9H2,1-2H3,(H,27,28,29)/t11-,18+,21-,22-/m1/s1	QTWKCJAINLFWKV-ZMQOCNJZSA-N	351314	1,4:3,6-dianhydro-5-({[4-[(4-bromo-2,3- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-glucitol::US9796704, Entry 46	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351314&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66954887	386053039							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694589	COC1CO[C@@H]2C(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)CO[C@H]12	InChI=1S/C23H23Cl2N3O5/c1-29-18-6-14-17(26-11-27-23(14)28-13-3-4-15(24)16(25)5-13)7-19(18)31-8-12-9-32-22-20(30-2)10-33-21(12)22/h3-7,11-12,20-22H,8-10H2,1-2H3,(H,26,27,28)/t12?,20?,21-,22-/m1/s1	VENHPOQTVRCHJV-YCZXQPQTSA-N	351346	1,4:3,6-dianhydro-2-deoxy-2-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5-O- methyl-D-threo-hexitol::US9796704, Entry 47	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351346&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802668	386053071							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694593	CO[C@H]1CO[C@@H]2[C@H](COc3cc4ncnc(Nc5cc(Cl)c(Cl)cc5F)c4cc3OC)CO[C@H]12	InChI=1S/C23H22Cl2FN3O5/c1-30-18-3-12-16(27-10-28-23(12)29-17-5-14(25)13(24)4-15(17)26)6-19(18)32-7-11-8-33-22-20(31-2)9-34-21(11)22/h3-6,10-11,20-22H,7-9H2,1-2H3,(H,27,28,29)/t11-,20+,21-,22-/m1/s1	KTBQYTJFMLOVMP-VNTFJFIFSA-N	351347	1,4:3,6-dianhydro-5-deoxy-5-({[4-[(4,5- dichloro-2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-glucitol::US9796704, Entry 48	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351347&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66954904	386053072							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694597	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCCC[C@H]2C(=O)N1	InChI=1S/C24H24Cl2FN5O3/c1-34-19-8-14-17(28-12-29-23(14)31-16-6-5-15(25)21(26)22(16)27)9-20(19)35-11-13-10-32-7-3-2-4-18(32)24(33)30-13/h5-6,8-9,12-13,18H,2-4,7,10-11H2,1H3,(H,30,33)(H,28,29,31)/t13-,18-/m0/s1	ZDTMGSSRQLKYTK-UGSOOPFHSA-N	351315	(3S,9aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydro-2H-pyrido[1,2- a]pyrazin-1(6H)-one::US9796704, Entry 49	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351315&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802612	386053040							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694601	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCCC[C@@H]2C(=O)N1	InChI=1S/C24H24Cl2FN5O3/c1-34-19-8-14-17(28-12-29-23(14)31-16-6-5-15(25)21(26)22(16)27)9-20(19)35-11-13-10-32-7-3-2-4-18(32)24(33)30-13/h5-6,8-9,12-13,18H,2-4,7,10-11H2,1H3,(H,30,33)(H,28,29,31)/t13-,18+/m0/s1	ZDTMGSSRQLKYTK-SCLBCKFNSA-N	351348	(3S,9aR)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydro-2H-pyrido[1,2- a]pyrazin-1(6H)-one::US9796704, Entry 50	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351348&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802634	386053073							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694605	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1	InChI=1S/C23H22Cl2FN5O3/c1-33-18-7-13-16(27-11-28-22(13)30-15-5-4-14(24)20(25)21(15)26)8-19(18)34-10-12-9-31-6-2-3-17(31)23(32)29-12/h4-5,7-8,11-12,17H,2-3,6,9-10H2,1H3,(H,29,32)(H,27,28,30)/t12-,17-/m0/s1	VXJCKEGWFQFYGD-SJCJKPOMSA-N	351316	(3S,8aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one::US9796704, Entry 51	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351316&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630923	386053041							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694609	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@@H]2C(=O)N1	InChI=1S/C23H22Cl2FN5O3/c1-33-18-7-13-16(27-11-28-22(13)30-15-5-4-14(24)20(25)21(15)26)8-19(18)34-10-12-9-31-6-2-3-17(31)23(32)29-12/h4-5,7-8,11-12,17H,2-3,6,9-10H2,1H3,(H,29,32)(H,27,28,30)/t12-,17+/m0/s1	VXJCKEGWFQFYGD-YVEFUNNKSA-N	351317	(3S,8aR)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one::US9796704, Entry 52	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351317&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630924	386053042							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694613	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1	InChI=1S/C23H22BrClFN5O3/c1-33-18-7-13-16(27-11-28-22(13)30-15-5-4-14(24)20(25)21(15)26)8-19(18)34-10-12-9-31-6-2-3-17(31)23(32)29-12/h4-5,7-8,11-12,17H,2-3,6,9-10H2,1H3,(H,29,32)(H,27,28,30)/t12-,17-/m0/s1	OEGXYNWEJSFYPO-SJCJKPOMSA-N	351318	(3S,8aS)-3-({[4-[(4-bromo-3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one::US9796704, Entry 53	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351318&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802807	386053043							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694617	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCC[C@@H]2C(=O)N1C	InChI=1S/C24H24Cl2FN5O3/c1-31-13(10-32-7-3-4-18(32)24(31)33)11-35-20-9-17-14(8-19(20)34-2)23(29-12-28-17)30-16-6-5-15(25)21(26)22(16)27/h5-6,8-9,12-13,18H,3-4,7,10-11H2,1-2H3,(H,28,29,30)/t13-,18-/m1/s1	RPLCLUCJTHAIOW-FZKQIMNGSA-N	351319	(3S,8aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)-2- methylhexahydropyrrolo[1,2-a]pyrazin-1(2H)- one::US9796704, Entry 54	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351319&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10436695	386053044							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694621	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCNC1CC2CCC(C1)N2C	InChI=1S/C25H29Cl2N5O2/c1-32-17-4-5-18(32)10-16(9-17)28-7-8-34-24-13-22-19(12-23(24)33-2)25(30-14-29-22)31-15-3-6-20(26)21(27)11-15/h3,6,11-14,16-18,28H,4-5,7-10H2,1-2H3,(H,29,30,31)	BKBIBLPFCFCOQQ-UHFFFAOYSA-N	351320	N-(3,4-dichlorophenyl)-7-({2-[(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)amino]ethyl}oxy)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 55	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351320	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351320&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10413710	386053045							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694625	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN2CSC[C@H]2CO1	InChI=1S/C22H22Cl2N4O3S/c1-29-20-5-16-19(25-11-26-22(16)27-13-2-3-17(23)18(24)4-13)6-21(20)31-9-15-7-28-12-32-10-14(28)8-30-15/h2-6,11,14-15H,7-10,12H2,1H3,(H,25,26,27)/t14-,15?/m1/s1	RFGYFZFUMBQSCW-GICMACPYSA-N	351321	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- {[(8aR)-tetrahydro-1H-[1,3]thiazolo[4,3- c][1,4]oxazin-6-ylmethyl]oxy}quinazolin-4- amine::US9796704, Entry 56	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351321&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802698	386053046							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694629	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CC2CCC(C1)N2C	InChI=1S/C25H28Cl2N4O2/c1-31-17-4-5-18(31)10-15(9-17)7-8-33-24-13-22-19(12-23(24)32-2)25(29-14-28-22)30-16-3-6-20(26)21(27)11-16/h3,6,11-15,17-18H,4-5,7-10H2,1-2H3,(H,28,29,30)	KLDWSPPOKXJTIT-UHFFFAOYSA-N	351322	N-(3,4-dichlorophenyl)-7-{[2-(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)ethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 57	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351322&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10480595	386053047							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694633	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CC2CCC(C1)N2C	InChI=1S/C24H26Cl2N4O2/c1-30-16-4-5-17(30)8-14(7-16)12-32-23-11-21-18(10-22(23)31-2)24(28-13-27-21)29-15-3-6-19(25)20(26)9-15/h3,6,9-11,13-14,16-17H,4-5,7-8,12H2,1-2H3,(H,27,28,29)	UAHJYZIKOGTHIW-UHFFFAOYSA-N	351323	N-(3,4-dichlorophenyl)-7-{[(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 58	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351323&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10005056	386053048							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694638	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1C[C@H]2CN(C)C[C@H]2C1	InChI=1S/C23H24Cl2N4O2/c1-29-10-13-5-16(6-14(13)11-29)31-22-9-20-17(8-21(22)30-2)23(27-12-26-20)28-15-3-4-18(24)19(25)7-15/h3-4,7-9,12-14,16H,5-6,10-11H2,1-2H3,(H,26,27,28)/t13-,14+,16?	DVEHRUCQBHJWFA-MZBDJJRSSA-N	351324	N-(3,4-dichlorophenyl)-7-{[(3aR,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]oxy}-6-(methyloxy)quinazolin-4-amine::US9796704, Entry 59	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351324&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10253661	386053049							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694643	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1CC2CCC(C1)N2C	InChI=1S/C23H24Cl2N4O2/c1-29-14-4-5-15(29)9-16(8-14)31-22-11-20-17(10-21(22)30-2)23(27-12-26-20)28-13-3-6-18(24)19(25)7-13/h3,6-7,10-12,14-16H,4-5,8-9H2,1-2H3,(H,26,27,28)	AXFITPBCUMOSEI-UHFFFAOYSA-N	351325	N-(3,4-dichlorophenyl)-7-[(8-methyl-8- azabicyclo[3.2.1]oct-3-yl)oxy]-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 60	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351325&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10321951	386053050							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694647	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3cc(Cl)c(Br)cc3F)c2cc1OC	InChI=1S/C22H20BrClFN3O5/c1-29-16-3-10-14(6-17(16)33-19-8-32-20-18(30-2)7-31-21(19)20)26-9-27-22(10)28-15-5-12(24)11(23)4-13(15)25/h3-6,9,18-21H,7-8H2,1-2H3,(H,26,27,28)/t18-,19-,20+,21+/m0/s1	UUILILXZMGYNLD-UWHLTILDSA-N	351326	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 61	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351326&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10325018	386053051							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694652	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC	InChI=1S/C22H20Cl2FN3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	KURAWEFNNHDHOM-ZCLUNYJNSA-N	351327	1,4:3,6-dianhydro-2-O-[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-5-O-methyl-L-iditol::US9796704, Entry 62	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351327&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10480937	386053052							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694656	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1OC	InChI=1S/C22H20BrClFN3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	BVPDJKPURONCRY-ZCLUNYJNSA-N	351328	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 63	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351328&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10392528	386053053							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694660	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3Cl)c2cc1OC	InChI=1S/C22H20Cl3N3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	IOXJGKZLPLFOBF-ZCLUNYJNSA-N	351329	1,4:3,6-dianhydro-2-O-methyl-5-O-{6- (methyloxy)-4-[(2,3,4- trichlorophenyl)amino]quinazolin-7-yl}-L-iditol::US9796704, Entry 64	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351329&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10369165	386053054							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694664	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3)c2cc1OC	InChI=1S/C22H21Cl2N3O5/c1-28-16-6-12-15(25-10-26-22(12)27-11-3-4-13(23)14(24)5-11)7-17(16)32-19-9-31-20-18(29-2)8-30-21(19)20/h3-7,10,18-21H,8-9H2,1-2H3,(H,25,26,27)/t18-,19-,20+,21+/m0/s1	ZAMYFBONNUIDDG-UWHLTILDSA-N	351330	1,4:3,6-dianhydro-5-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-O-methyl-D- xylo-hexitol::US9796704, Entry 65::US9796704, Entry 72	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351330&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10412767	386053055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694668	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3Cl)c2cc1OC	InChI=1S/C22H20BrCl2N3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(23)18(24)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	ZLFBWBUGVAULCA-ZCLUNYJNSA-N	351331	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-2,3- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 66	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351331&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347695	386053056							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694672	COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OCC21OCCO1	InChI=1S/C23H21BrClN3O6/c1-29-17-7-13-16(26-11-27-22(13)28-12-2-3-14(24)15(25)6-12)8-18(17)34-19-9-30-21-20(19)31-10-23(21)32-4-5-33-23/h2-3,6-8,11,19-21H,4-5,9-10H2,1H3,(H,26,27,28)/t19-,20+,21-/m0/s1	ZDOPWPQLWDULEV-HBMCJLEFSA-N	351332	US9796704, Entry 67::dianhydro-5-O-[4-[(4-bromo-3- chlorophenyl)amino]-6-(methyloxy)- quinazolin-7-yl]-L-sorbose ethylene glycol acetal	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351332&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10482693	386053057							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694677	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3F)c2cc1OC	InChI=1S/C22H20ClF2N3O5/c1-29-14-5-10-13(6-15(14)33-17-8-32-20-16(30-2)7-31-21(17)20)26-9-27-22(10)28-12-4-3-11(24)18(23)19(12)25/h3-6,9,16-17,20-21H,7-8H2,1-2H3,(H,26,27,28)/t16-,17-,20+,21+/m0/s1	SJEYKCLWHCAMQL-ZCLUNYJNSA-N	351333	1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2,4- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 68	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351333&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10390394	386053058							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694681	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1OC	InChI=1S/C22H20Cl2FN3O5/c1-29-16-3-10-14(6-17(16)33-19-8-32-20-18(30-2)7-31-21(19)20)26-9-27-22(10)28-15-5-12(24)11(23)4-13(15)25/h3-6,9,18-21H,7-8H2,1-2H3,(H,26,27,28)/t18-,19-,20+,21+/m0/s1	FDJOKRBUPKWJTB-UWHLTILDSA-N	351349	1,4:3,6-dianhydro-2-O-[4-[(4,5-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-5-O-methyl-L-iditol::US9796704, Entry 69	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351349&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11755547	386053074							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694686	COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@@H]2[C@H](CO[C@H]12)OC(F)F	InChI=1S/C22H19BrClF2N3O5/c1-30-15-5-11-14(27-9-28-21(11)29-10-2-3-12(23)13(24)4-10)6-16(15)33-17-7-31-20-18(34-22(25)26)8-32-19(17)20/h2-6,9,17-20,22H,7-8H2,1H3,(H,27,28,29)/t17-,18-,19+,20+/m0/s1	XHBINYIIFGVWSM-VNTMZGSJSA-N	351350	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O- (difluoromethyl)-L-iditol::US9796704, Entry 70	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351350&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10437760	386053075							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694690	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC	InChI=1S/C22H21ClFN3O5/c1-28-15-6-11-14(25-10-26-22(11)27-13-5-3-4-12(23)19(13)24)7-16(15)32-18-9-31-20-17(29-2)8-30-21(18)20/h3-7,10,17-18,20-21H,8-9H2,1-2H3,(H,25,26,27)/t17-,18-,20+,21+/m0/s1	MBKCHTMJAMAWPC-FMWKFLBASA-N	351351	1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-5-O-methyl-L-iditol::US9796704, Entry 71	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351351&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10253774	386053076							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694694	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3)c2cc1OC	InChI=1S/C22H21Cl2N3O5/c1-28-16-6-12-15(25-10-26-22(12)27-11-3-4-13(23)14(24)5-11)7-17(16)32-19-9-31-20-18(29-2)8-30-21(19)20/h3-7,10,18-21H,8-9H2,1-2H3,(H,25,26,27)/t18-,19-,20+,21+/m0/s1	ZAMYFBONNUIDDG-UWHLTILDSA-N	351330	1,4:3,6-dianhydro-5-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-O-methyl-D- xylo-hexitol::US9796704, Entry 65::US9796704, Entry 72	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351330&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10412767	386053055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694699	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC	InChI=1S/C22H21BrClN3O5/c1-28-16-6-12-15(25-10-26-22(12)27-11-3-4-13(23)14(24)5-11)7-17(16)32-19-9-31-20-18(29-2)8-30-21(19)20/h3-7,10,18-21H,8-9H2,1-2H3,(H,25,26,27)/t18-,19-,20+,21+/m0/s1	OUEOJFCFMCXADD-UWHLTILDSA-N	351353	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 73	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351353&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10346676	386053077							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694703	CCO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC	InChI=1S/C23H23BrClN3O5/c1-3-30-19-9-31-22-20(10-32-21(19)22)33-18-8-16-13(7-17(18)29-2)23(27-11-26-16)28-12-4-5-14(24)15(25)6-12/h4-8,11,19-22H,3,9-10H2,1-2H3,(H,26,27,28)/t19-,20-,21+,22+/m0/s1	RVMLSAUWFLLGAT-FNAHDJPLSA-N	351354	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-ethyl-L-iditol::US9796704, Entry 74	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351354&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11756978	386053078							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694707	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3cccc(Br)c3C)c2cc1OC	InChI=1S/C23H24BrN3O5/c1-12-14(24)5-4-6-15(12)27-23-13-7-17(28-2)18(8-16(13)25-11-26-23)32-20-10-31-21-19(29-3)9-30-22(20)21/h4-8,11,19-22H,9-10H2,1-3H3,(H,25,26,27)/t19-,20-,21+,22+/m0/s1	GAKPIAPJVGZESM-FNAHDJPLSA-N	351355	1,4:3,6-dianhydro-2-O-[4-[(3-bromo-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 75	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351355&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10029004	386053079							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694711	CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3cccc(Cl)c3C)c2cc1OC	InChI=1S/C23H24ClN3O5/c1-12-14(24)5-4-6-15(12)27-23-13-7-17(28-2)18(8-16(13)25-11-26-23)32-20-10-31-21-19(29-3)9-30-22(20)21/h4-8,11,19-22H,9-10H2,1-3H3,(H,25,26,27)/t19-,20-,21+,22+/m0/s1	ZTASYFQODPYQIW-FNAHDJPLSA-N	351356	1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 76	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351356&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10095656	386053080							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694715	COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@@H]2CCO[C@H]12	InChI=1S/C21H19BrClN3O4/c1-27-17-7-12-15(8-18(17)30-19-9-29-16-4-5-28-20(16)19)24-10-25-21(12)26-11-2-3-13(22)14(23)6-11/h2-3,6-8,10,16,19-20H,4-5,9H2,1H3,(H,24,25,26)/t16-,19+,20+/m1/s1	JJQTYTQYXOULRB-UXPWSPDFSA-N	351357	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-deoxy-D-xylo- hexitol::US9796704, Entry 77	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351357&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10345562	386053081							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694720	CO[C@@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC	InChI=1S/C22H21BrClN3O5/c1-28-16-6-12-15(25-10-26-22(12)27-11-3-4-13(23)14(24)5-11)7-17(16)32-19-9-31-20-18(29-2)8-30-21(19)20/h3-7,10,18-21H,8-9H2,1-2H3,(H,25,26,27)/t18-,19+,20-,21-/m1/s1	OUEOJFCFMCXADD-PLACYPQZSA-N	351358	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-D- glucitol::US9796704, Entry 78	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351358&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10075455	386053082							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694725	CO[C@@H]1O[C@@H]2[C@H](CO[C@@H]2[C@H]1OC)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC	InChI=1S/C23H23BrClN3O6/c1-29-16-7-12-15(26-10-27-22(12)28-11-4-5-13(24)14(25)6-11)8-17(16)33-18-9-32-20-19(18)34-23(31-3)21(20)30-2/h4-8,10,18-21,23H,9H2,1-3H3,(H,26,27,28)/t18-,19+,20-,21+,23+/m0/s1	NJKVUYJCCZCQNK-UKPGDCENSA-N	351359	US9796704, Entry 79::methyl 3,6-anhydro-5-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-O-methyl- alpha-L-idofuranoside	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351359&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10415222	386053083							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694729	COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1O[C@@H]1OC(C)(C)OC21	InChI=1S/C24H23BrClN3O6/c1-24(2)34-21-20-19(33-23(21)35-24)18(9-31-20)32-17-8-15-12(7-16(17)30-3)22(28-10-27-15)29-11-4-5-13(25)14(26)6-11/h4-8,10,18-21,23H,9H2,1-3H3,(H,27,28,29)/t18-,19+,20-,21?,23+/m0/s1	VKRSAHZIVGFNMU-IEHHRWIQSA-N	351360	3,6-anhydro-5-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-1,2-O-(1- methylethylidene)-beta-L-xylo-hexofuranose::US9796704, Entry 80	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351360&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10053645	386053084							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694733	COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OCC2=C	InChI=1S/C22H19BrClN3O4/c1-11-8-29-21-19(9-30-20(11)21)31-18-7-16-13(6-17(18)28-2)22(26-10-25-16)27-12-3-4-14(23)15(24)5-12/h3-7,10,19-21H,1,8-9H2,2H3,(H,25,26,27)/t19-,20+,21+/m0/s1	OGNKTNDFGPEFFD-PWRODBHTSA-N	351361	1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-deoxy-5- methylidene-D-xylo-hexitol::US9796704, Entry 81	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351361&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802548	386053085							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694737	CO[C@H]1O[C@@H]2[C@H](CO[C@@H]2[C@H]1OC)Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC	InChI=1S/C23H23BrClN3O6/c1-29-16-7-12-15(26-10-27-22(12)28-11-4-5-13(24)14(25)6-11)8-17(16)33-18-9-32-20-19(18)34-23(31-3)21(20)30-2/h4-8,10,18-21,23H,9H2,1-3H3,(H,26,27,28)/t18-,19+,20-,21+,23-/m0/s1	NJKVUYJCCZCQNK-FPQOSCNCSA-N	351362	US9796704, Entry 82::methyl 3,6-anhydro-5-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-O-methyl-beta- L-idofuranoside	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351362&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802622	386053086							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694741	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OCC1CCC2CCCCN2C1	InChI=1S/C25H27Cl2FN4O2/c1-33-21-10-17-20(29-14-30-25(17)31-19-8-7-18(26)23(27)24(19)28)11-22(21)34-13-15-5-6-16-4-2-3-9-32(16)12-15/h7-8,10-11,14-16H,2-6,9,12-13H2,1H3,(H,29,30,31)	RZKGVOJSKFTTBA-UHFFFAOYSA-N	351363	N-(3,4-dichloro-2-fluorophenyl)-6- (methyloxy)-7-[(octahydro-2H-quinolizin-3- ylmethyl)oxy]quinazolin-4-amine::US9796704, Entry 83	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351363&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630902	386053087							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694745	COc1cc2c(Nc3ccc(F)c(F)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17F4N3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(23)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(22)17(24)18(12)25/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1	ZNTUEQOGCBDJQV-PDDAWLJDSA-N	351364	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-{6- (methyloxy)-4-[(2,3,4- trifluorophenyl)amino]quinazolin-7-yl}-D-iditol::US9796704, Entry 84	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351364&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838554	386053088							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694749	COc1cc2c(Nc3ccc(F)cc3Cl)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18ClF2N3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-14-3-2-10(23)4-12(14)22/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	UQJWQNWEZPXTRQ-YFMMTPMMSA-N	351365	1,4:3,6-dianhydro-5-O-[4-[(2-chloro4- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-2-deoxy-2-fluoro-D-iditol::US9796704, Entry 85	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351365&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838566	386053089							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694753	COc1cc2c(Nc3ccc(F)cc3Br)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18BrF2N3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-14-3-2-10(23)4-12(14)22/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	IVTMGIFJCKLZRO-YFMMTPMMSA-N	351366	1,4:3,6-dianhydro-5-O-[4-[(2-bromo-4- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-2-deoxy-2-fluoro-D-iditol::US9796704, Entry 86	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351366&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838574	386053090							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694757	COc1cc2c(Nc3c(F)cccc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18F3N3O4/c1-28-15-5-10-14(6-16(15)31-17-8-30-19-13(24)7-29-20(17)19)25-9-26-21(10)27-18-11(22)3-2-4-12(18)23/h2-6,9,13,17,19-20H,7-8H2,1H3,(H,25,26,27)/t13-,17-,19+,20+/m1/s1	WFNAULMUNPRODX-PTLICHBZSA-N	351367	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(2,6- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 87	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351367&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838645	386053091							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694761	COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18ClF2N3O4/c1-28-15-5-10-14(6-16(15)31-17-8-30-19-12(23)7-29-20(17)19)25-9-26-21(10)27-13-4-2-3-11(22)18(13)24/h2-6,9,12,17,19-20H,7-8H2,1H3,(H,25,26,27)/t12-,17-,19+,20+/m1/s1	GBVHHGINCYVVRZ-GISJFGRKSA-N	351368	1,4:3,6-dianhydro-5-O-[4-[(3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-2-deoxy-2-fluoro-D-iditol::US9796704, Entry 88	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351368	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351368&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838468	386053092							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694765	COc1cc2c(Nc3ccc(F)c(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18F5N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(11)30-10-2-3-13(23)12(4-10)22(25,26)27/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1	PSMXKRAQDFGMBM-FCDRMGDPSA-N	351369	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4- {[4-fluoro-3-(trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-D-iditol::US9796704, Entry 89	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838476	386053093							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694769	COc1cc2c(Nc3ccc(F)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18F3N3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-14-3-2-10(22)4-12(14)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	PBZBHUPNRAUVJF-YFMMTPMMSA-N	351370	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(2,4- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 90	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838602	386053094							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694773	COc1cc2c(Nc3cc(F)ccc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18F3N3O4/c1-28-16-5-11-14(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-15-4-10(22)2-3-12(15)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	KNQFEIWYUMJEJW-YFMMTPMMSA-N	351371	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(2,5- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 91	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838487	386053095							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694777	COc1cc2c(Nc3cccc(F)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18F3N3O4/c1-28-15-5-10-14(6-16(15)31-17-8-30-19-12(23)7-29-20(17)19)25-9-26-21(10)27-13-4-2-3-11(22)18(13)24/h2-6,9,12,17,19-20H,7-8H2,1H3,(H,25,26,27)/t12-,17-,19+,20+/m1/s1	MNDLFEMDUVUZEA-GISJFGRKSA-N	351372	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(2,3- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 92	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802911	386053096							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694781	COc1cc2c(Nc3cc(Cl)ccc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18ClF2N3O4/c1-28-16-5-11-14(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-15-4-10(22)2-3-12(15)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	IUKSUNXUYRVVIQ-YFMMTPMMSA-N	351373	1,4:3,6-dianhydro-5-O-[4-[(5-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-2-deoxy-2-fluoro-D-iditol::US9796704, Entry 93	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838475	386053097							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694785	COc1cc2c(Nc3cc(F)cc(F)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18F3N3O4/c1-28-16-5-13-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(13)27-12-3-10(22)2-11(23)4-12/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	NWWJHGTVZUZRMP-FCDRMGDPSA-N	351374	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,5- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 94	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838681	386053098							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694789	COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18ClF2N3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-13(23)12(22)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	VQRNHLREZMWHGF-FCDRMGDPSA-N	351375	1,4:3,6-dianhydro-5-O-[4-[(3-chloro-4- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-2-deoxy-2-fluoro-D-iditol::US9796704, Entry 95	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838493	386053099							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694793	COc1cc2c(Nc3ccc(Br)cc3Cl)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18BrClFN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-14-3-2-10(22)4-12(14)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	REFNEWGQRNQDHZ-YFMMTPMMSA-N	351376	1,4:3,6-dianhydro-5-O-[4-[(4-bromo-2- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 96	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838581	386053100							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694797	COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17Cl2F2N3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(24)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(22)17(23)18(12)25/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1	CQIIIEIHBWOUOM-PDDAWLJDSA-N	351377	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichloro-2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 97	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838678	386053101							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694802	COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17BrClF2N3O4/c1-29-16-2-9-14(5-17(16)32-18-7-31-19-13(25)6-30-20(18)19)26-8-27-21(9)28-15-4-11(23)10(22)3-12(15)24/h2-5,8,13,18-20H,6-7H2,1H3,(H,26,27,28)/t13-,18-,19+,20+/m1/s1	YALKSQBVLCYSFM-YFMMTPMMSA-N	351378	1,4:3,6-dianhydro-5-O-[4-[(4-bromo-5-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 98	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351378&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838585	386053102							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694806	COc1cc2c(Nc3cc(F)c(F)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17F4N3O4/c1-29-16-2-9-14(5-17(16)32-18-7-31-19-13(25)6-30-20(18)19)26-8-27-21(9)28-15-4-11(23)10(22)3-12(15)24/h2-5,8,13,18-20H,6-7H2,1H3,(H,26,27,28)/t13-,18-,19+,20+/m1/s1	GESHUZBGGLGNGZ-YFMMTPMMSA-N	351379	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-{6- (methyloxy)-4-[(2,4,5- trifluorophenyl)amino]quinazolin-7-yl}-D-iditol::US9796704, Entry 99	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838478	386053103							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694810	COc1cc2c(Nc3c(F)cc(F)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17F4N3O4/c1-29-15-4-10-14(5-16(15)32-17-7-31-19-13(25)6-30-20(17)19)26-8-27-21(10)28-18-11(23)2-9(22)3-12(18)24/h2-5,8,13,17,19-20H,6-7H2,1H3,(H,26,27,28)/t13-,17-,19+,20+/m1/s1	SYTDXYNETZANOI-PTLICHBZSA-N	351380	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-{6- (methyloxy)-4-[(2,4,6- trifluorophenyl)amino]quinazolin-7-yl}-D-iditol::US9796704, Entry 100	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838485	386053104							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694814	COc1cc2c(Nc3cc(F)c(Oc4ccc(Cl)cc4)c(F)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C27H21ClF3N3O5/c1-35-21-8-16-20(9-22(21)39-23-11-37-25-19(31)10-36-26(23)25)32-12-33-27(16)34-14-6-17(29)24(18(30)7-14)38-15-4-2-13(28)3-5-15/h2-9,12,19,23,25-26H,10-11H2,1H3,(H,32,33,34)/t19-,23-,25+,26+/m1/s1	XXVRAEWUOFARHO-HOLAQXKLSA-N	351381	1,4:3,6-dianhydro-5-O-[4-({4-[(4- chlorophenyl)oxy]-3,5-difluorophenyl}amino)- 6-(methyloxy)quinazolin-7-yl]-2-deoxy-2- fluoro-D-iditol::US9796704, Entry 101	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838651	386053105							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694818	COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17BrClF2N3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(24)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(22)17(23)18(12)25/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1	HQHKCYQAKIHFNI-PDDAWLJDSA-N	351382	1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 102	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351382&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838610	386053106							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694822	COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17BrCl2FN3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(25)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(22)17(23)18(12)24/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1	UUPSSROUZJUAGT-PDDAWLJDSA-N	351383	1,4:3,6-dianhydro-5-O-[4-[(4-bromo-2,3- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 103	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838692	386053107							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694826	COc1cc2c(Nc3cc(F)c(Br)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17BrClF2N3O4/c1-29-15-4-10-14(5-16(15)32-17-7-31-19-13(25)6-30-20(17)19)26-8-27-21(10)28-9-2-11(23)18(22)12(24)3-9/h2-5,8,13,17,19-20H,6-7H2,1H3,(H,26,27,28)/t13-,17-,19+,20+/m1/s1	WSMGNYODPMGZLL-PTLICHBZSA-N	351384	1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chloro- 5-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 104	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838589	386053108							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694830	COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17Cl2F2N3O4/c1-29-16-2-9-14(5-17(16)32-18-7-31-19-13(25)6-30-20(18)19)26-8-27-21(9)28-15-4-11(23)10(22)3-12(15)24/h2-5,8,13,18-20H,6-7H2,1H3,(H,26,27,28)/t13-,18-,19+,20+/m1/s1	RNMZCDDYUSJWBE-YFMMTPMMSA-N	351385	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(4,5- dichloro-2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 105	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351385&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838456	386053109							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694834	COc1cc2c(Nc3ccc(Cl)c(Cl)c3Cl)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17Cl3FN3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(25)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(22)17(23)18(12)24/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1	PDTLXTDXRUZIGN-PDDAWLJDSA-N	351386	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-{6- (methyloxy)-4-[(2,3,4- trichlorophenyl)amino]quinazolin-7-yl}-D-iditol::US9796704, Entry 106	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838549	386053110							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694838	COc1cc2c(Nc3cc(Cl)c(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17Cl3FN3O4/c1-29-15-4-10-14(5-16(15)32-17-7-31-19-13(25)6-30-20(17)19)26-8-27-21(10)28-9-2-11(22)18(24)12(23)3-9/h2-5,8,13,17,19-20H,6-7H2,1H3,(H,26,27,28)/t13-,17-,19+,20+/m1/s1	XVPSLKGHDHFMEM-PTLICHBZSA-N	351387	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-{6- (methyloxy)-4-[(3,4,5- trichlorophenyl)amino]quinazolin-7-yl}-D-iditol::US9796704, Entry 107	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838655	386053111							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694842	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18BrF2N3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-14-3-2-10(22)4-12(14)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	UOXGDSKFAKYBGU-YFMMTPMMSA-N	351388	1,4:3,6-dianhydro-5-O-[4-[(4-bromo-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-2-deoxy-2-fluoro-D-iditol::US9796704, Entry 108	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351388&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10368459	386053112							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694846	COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18ClF2N3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-14-3-2-10(22)4-12(14)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	PQYBSOBFELGWEF-YFMMTPMMSA-N	351389	1,4:3,6-dianhydro-5-O-[4-[(4-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-2-deoxy-2-fluoro-D-iditol::US9796704, Entry 109	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10389038	386053113							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694850	COc1cc2c(Nc3cccc(Cl)c3C)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H21ClFN3O4/c1-11-13(23)4-3-5-15(11)27-22-12-6-17(28-2)18(7-16(12)25-10-26-22)31-19-9-30-20-14(24)8-29-21(19)20/h3-7,10,14,19-21H,8-9H2,1-2H3,(H,25,26,27)/t14-,19-,20+,21+/m1/s1	RJGUQSMXHFQXPD-PLBGURBNSA-N	351390	1,4:3,6-dianhydro-5-O-[4-[(3-chloro-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 110	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351390&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10321317	386053114							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694854	COc1cc2c(Nc3ccc(F)c(F)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18F3N3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-12(22)13(23)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	HZOGQCYCMSFESW-FCDRMGDPSA-N	351391	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 111	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351391&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10365561	386053115							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694859	COc1cc2c(Nc3ccccc3Cl)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19ClFN3O4/c1-27-16-6-11-15(24-10-25-21(11)26-14-5-3-2-4-12(14)22)7-17(16)30-18-9-29-19-13(23)8-28-20(18)19/h2-7,10,13,18-20H,8-9H2,1H3,(H,24,25,26)/t13-,18-,19+,20+/m1/s1	UIELDVYKNRNSEM-YFMMTPMMSA-N	351392	1,4:3,6-dianhydro-5-O-[4-[(2- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 112	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351392&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10365480	386053116							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694863	COc1cc2c(Nc3ccccc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19F2N3O4/c1-27-16-6-11-15(24-10-25-21(11)26-14-5-3-2-4-12(14)22)7-17(16)30-18-9-29-19-13(23)8-28-20(18)19/h2-7,10,13,18-20H,8-9H2,1H3,(H,24,25,26)/t13-,18-,19+,20+/m1/s1	GNBFLDHHHUBBFG-YFMMTPMMSA-N	351393	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4- [(2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-D-iditol::US9796704, Entry 113	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351393&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10001881	386053117							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694867	COc1cc2c(Nc3cccc(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19ClFN3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-3-11(22)5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1	DJXUANYGYXJJAE-FCDRMGDPSA-N	351394	1,4:3,6-dianhydro-5-O-[4-[(3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 114	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351394&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10025780	386053118							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694871	COc1cc2c(Nc3ccc(F)cc3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19F2N3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-11(22)3-5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1	FSNXDZZUWFZSPA-FCDRMGDPSA-N	351395	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4- [(4-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-D-iditol::US9796704, Entry 115	Epidermal growth factor receptor	Homo sapiens		 525							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351395&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10093273	386053119							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694875	COc1cc2c(Nc3ccc(Cl)cc3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19ClFN3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-11(22)3-5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1	YXCHYSQVLDVUOJ-FCDRMGDPSA-N	351396	1,4:3,6-dianhydro-5-O-[4-[(4- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 116	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351396&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10002884	386053120							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694879	COc1cc2c(Nc3ccc(Cl)cc3Cl)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-14-3-2-10(22)4-12(14)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	VPMFDTGNFBVOSP-YFMMTPMMSA-N	351397	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(2,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 117	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351397&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10050178	386053121							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694884	COc1cc2c(Nc3cc(Cl)ccc3Cl)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-14(6-17(16)31-18-8-30-19-13(24)7-29-20(18)19)25-9-26-21(11)27-15-4-10(22)2-3-12(15)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,25,26,27)/t13-,18-,19+,20+/m1/s1	IXUDYVHGCQIEDJ-YFMMTPMMSA-N	351398	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(2,5- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 118	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351398&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9981975	386053122							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694888	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-12(22)13(23)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	ZDHUWTTUQHECMO-FCDRMGDPSA-N	351399	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 119	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351399&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10457243	386053123							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694893	COc1cc2c(Nc3c(F)cc(F)cc3Br)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17BrF3N3O4/c1-29-15-4-10-14(5-16(15)32-17-7-31-19-13(25)6-30-20(17)19)26-8-27-21(10)28-18-11(22)2-9(23)3-12(18)24/h2-5,8,13,17,19-20H,6-7H2,1H3,(H,26,27,28)/t13-,17-,19+,20+/m1/s1	HJOMYFVOXGNASK-PTLICHBZSA-N	351400	1,4:3,6-dianhydro-5-O-[4-[(2-bromo-4,6- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 120	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351400&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10391671	386053124							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694897	COc1cc2c(Nc3ccc(Cl)c(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18ClF4N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(11)30-10-2-3-13(23)12(4-10)22(25,26)27/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1	OGAXAZKIMMCTIZ-FCDRMGDPSA-N	351401	1,4:3,6-dianhydro-5-O-[4-{[4-chloro-3- (trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 121	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10458636	386053125							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694901	COc1cc2c(Nc3cc(ccc3Cl)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18ClF4N3O4/c1-31-16-5-11-14(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-15-4-10(22(25,26)27)2-3-12(15)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1	SMLYFAJYRKAOPL-YFMMTPMMSA-N	351402	1,4:3,6-dianhydro-5-O-[4-{[2-chloro-5- (trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 122	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10323699	386053126							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694905	COc1cc2c(Nc3cccc(c3F)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18F5N3O4/c1-31-15-5-10-14(6-16(15)34-17-8-33-19-12(23)7-32-20(17)19)28-9-29-21(10)30-13-4-2-3-11(18(13)24)22(25,26)27/h2-6,9,12,17,19-20H,7-8H2,1H3,(H,28,29,30)/t12-,17-,19+,20+/m1/s1	VWCXCYRYWPKZNG-GISJFGRKSA-N	351403	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4- {[2-fluoro-3-(trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-D-iditol::US9796704, Entry 123	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10096804	386053127							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694909	COc1cc2c(Nc3cc(ccc3Br)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18BrF4N3O4/c1-31-16-5-11-14(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-15-4-10(22(25,26)27)2-3-12(15)23/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1	IXLSYYGZAKKXCH-YFMMTPMMSA-N	351404	1,4:3,6-dianhydro-5-O-[4-{[2-bromo-5- (trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 124	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10256852	386053128							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694913	COc1cc2c(Nc3ccc(cc3Br)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18BrF4N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-14-3-2-10(4-12(14)23)22(25,26)27/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1	HMKNXLABKFFLGV-YFMMTPMMSA-N	351405	1,4:3,6-dianhydro-5-O-[4-{[2-bromo-4- (trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 125	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10460027	386053129							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694918	COc1cc2c(Nc3ccc(F)cc3C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18F5N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-14-3-2-10(23)4-12(14)22(25,26)27/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1	QPQAGSRLQDSAGQ-YFMMTPMMSA-N	351406	1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4- {[4-fluoro-2-(trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-D-iditol::US9796704, Entry 126	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351406&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10028232	386053130							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694922	COc1cc2c(Nc3cc(Br)cc(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H18BrF4N3O4/c1-31-16-5-13-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(13)30-12-3-10(22(25,26)27)2-11(23)4-12/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1	FSSHDIKQMARYSU-FCDRMGDPSA-N	351407	1,4:3,6-dianhydro-5-O-[4-{[3-bromo-5- (trifluoromethyl)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 127	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10325099	386053131							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694927	COc1cc2c(Nc3ccccc3Br)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19BrFN3O4/c1-27-16-6-11-15(24-10-25-21(11)26-14-5-3-2-4-12(14)22)7-17(16)30-18-9-29-19-13(23)8-28-20(18)19/h2-7,10,13,18-20H,8-9H2,1H3,(H,24,25,26)/t13-,18-,19+,20+/m1/s1	NAOSUZSDORYMKP-YFMMTPMMSA-N	351408	1,4:3,6-dianhydro-5-O-[4-[(2- bromophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 128	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10073677	386053132							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694931	COc1cc2c(Nc3cccc(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19BrFN3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-3-11(22)5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1	HAVVSQSFGAQFOW-FCDRMGDPSA-N	351409	1,4:3,6-dianhydro-5-O-[4-[(3- bromophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 129	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			9982413	386053133							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694935	COc1cc2c(Nc3ccc(Br)cc3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H19BrFN3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-11(22)3-5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1	COWKEXRPFBNPOQ-FCDRMGDPSA-N	351410	1,4:3,6-dianhydro-5-O-[4-[(4- bromophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 130	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351410&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10096516	386053134							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694939	COc1cc2c(Nc3ccc(C)c(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H21BrFN3O4/c1-11-3-4-12(5-14(11)23)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-15(24)8-29-21(19)20/h3-7,10,15,19-21H,8-9H2,1-2H3,(H,25,26,27)/t15-,19-,20+,21+/m1/s1	PFBDUGXDPNHKAM-IDCXYZFESA-N	351411	1,4:3,6-dianhydro-5-O-[4-[(3-bromo-4- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 131	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10005786	386053135							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694943	COc1cc2c(Nc3ccc(Cl)cc3C)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C22H21ClFN3O4/c1-11-5-12(23)3-4-15(11)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-14(24)8-29-21(19)20/h3-7,10,14,19-21H,8-9H2,1-2H3,(H,25,26,27)/t14-,19-,20+,21+/m1/s1	LMPSDBKQPWYZFY-PLBGURBNSA-N	351412	1,4:3,6-dianhydro-5-O-[4-[(5-chloro-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 132	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351412&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10072223	386053136							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694947	COc1cc2c(Nc3cc(C)cc(C)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C23H24FN3O4/c1-12-4-13(2)6-14(5-12)27-23-15-7-18(28-3)19(8-17(15)25-11-26-23)31-20-10-30-21-16(24)9-29-22(20)21/h4-8,11,16,20-22H,9-10H2,1-3H3,(H,25,26,27)/t16-,20-,21+,22+/m1/s1	MBPRKKURYAKGON-XXMUNEJQSA-N	351413	1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,5- dimethylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 133	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351413&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10048038	386053137							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694951	COc1ccc(OC)c(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)c1	InChI=1S/C23H24FN3O6/c1-28-12-4-5-17(29-2)16(6-12)27-23-13-7-18(30-3)19(8-15(13)25-11-26-23)33-20-10-32-21-14(24)9-31-22(20)21/h4-8,11,14,20-22H,9-10H2,1-3H3,(H,25,26,27)/t14-,20-,21+,22+/m1/s1	BLZCIAZUKSOFTP-KAJMWERUSA-N	351414	1,4:3,6-dianhydro-5-O-[4-{[2,5- bis(methyloxy)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 134	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351414&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10321865	386053138							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694955	COc1cc(OC)c(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)cc1Cl	InChI=1S/C23H23ClFN3O6/c1-29-16-7-17(30-2)15(5-12(16)24)28-23-11-4-18(31-3)19(6-14(11)26-10-27-23)34-20-9-33-21-13(25)8-32-22(20)21/h4-7,10,13,20-22H,8-9H2,1-3H3,(H,26,27,28)/t13-,20-,21+,22+/m1/s1	IIBGPAMZGFHRRY-TVKMXBCISA-N	351415	1,4:3,6-dianhydro-5-O-[4-{[5-chloro-2,4- bis(methyloxy)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 135	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351415&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802852	386053139							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694959	COc1cc(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)c(OC)cc1Cl	InChI=1S/C23H23ClFN3O6/c1-29-16-7-15(17(30-2)5-12(16)24)28-23-11-4-18(31-3)19(6-14(11)26-10-27-23)34-20-9-33-21-13(25)8-32-22(20)21/h4-7,10,13,20-22H,8-9H2,1-3H3,(H,26,27,28)/t13-,20-,21+,22+/m1/s1	SLWMPPADXCAMND-TVKMXBCISA-N	351416	1,4:3,6-dianhydro-5-O-[4-{[4-chloro-2,5- bis(methyloxy)phenyl]amino}-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 136	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802551	386053140							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694963	COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12	InChI=1S/C21H17ClF3N3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(24)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(23)17(22)18(12)25/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1	QKKRTUHQIAZEDD-PDDAWLJDSA-N	351417	1,4:3,6-dianhydro-5-O-[4-[(3-chloro-2,4- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 137	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			66838565	386053141							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694967	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(CN(C)C)n1	InChI=1S/C21H20Cl2N6O3/c1-29(2)9-20-27-19(28-32-20)10-31-18-8-16-13(7-17(18)30-3)21(25-11-24-16)26-12-4-5-14(22)15(23)6-12/h4-8,11H,9-10H2,1-3H3,(H,24,25,26)	PWCBBEMFFOGHOA-UHFFFAOYSA-N	351418	N-(3,4-dichlorophenyl)-7-[({5- [(dimethylamino)methyl]-1,2,4-oxadiazol-3- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 138	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630952	386053142							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694971	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN(C)C)no1	InChI=1S/C21H20Cl2N6O3/c1-29(2)9-19-27-20(32-28-19)10-31-18-8-16-13(7-17(18)30-3)21(25-11-24-16)26-12-4-5-14(22)15(23)6-12/h4-8,11H,9-10H2,1-3H3,(H,24,25,26)	DBXVNVVGMHBBOC-UHFFFAOYSA-N	351419	N-(3,4-dichlorophenyl)-7-[({3- [(dimethylamino)methyl]-1,2,4-oxadiazol-5- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 139	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630958	386053143							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694975	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCN(C)CC2)no1	InChI=1S/C24H25Cl2N7O3/c1-32-5-7-33(8-6-32)12-22-30-23(36-31-22)13-35-21-11-19-16(10-20(21)34-2)24(28-14-27-19)29-15-3-4-17(25)18(26)9-15/h3-4,9-11,14H,5-8,12-13H2,1-2H3,(H,27,28,29)	OZDWKTRNNHXKQT-UHFFFAOYSA-N	351420	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(4-methylpiperazin-1-yl)methyl]-1,2,4- oxadiazol-5-yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 140	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351420&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630956	386053144							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694979	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCNCC1	InChI=1S/C23H22Cl2N6O3/c1-32-19-9-15-18(27-12-28-22(15)29-14-2-3-16(24)17(25)8-14)10-20(19)33-11-21-30-23(34-31-21)13-4-6-26-7-5-13/h2-3,8-10,12-13,26H,4-7,11H2,1H3,(H,27,28,29)	LFVVFUDFYJQWPX-UHFFFAOYSA-N	351421	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piperidin-4-yl-1,2,4-oxadiazol-3- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 141	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351421&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630951	386053145							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694983	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCN(C)CC1	InChI=1S/C24H24Cl2N6O3/c1-32-7-5-14(6-8-32)24-30-22(31-35-24)12-34-21-11-19-16(10-20(21)33-2)23(28-13-27-19)29-15-3-4-17(25)18(26)9-15/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,27,28,29)	NLASQQGOHZWAKY-UHFFFAOYSA-N	351422	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5- (1-methylpiperidin-4-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 142	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351422&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630950	386053146							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694987	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCOCC2)no1	InChI=1S/C23H22Cl2N6O4/c1-32-19-9-15-18(26-13-27-23(15)28-14-2-3-16(24)17(25)8-14)10-20(19)34-12-22-29-21(30-35-22)11-31-4-6-33-7-5-31/h2-3,8-10,13H,4-7,11-12H2,1H3,(H,26,27,28)	RORFVUDLEIRGQY-UHFFFAOYSA-N	351423	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[3- (morpholin-4-ylmethyl)-1,2,4-oxadiazol-5- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 143	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351423&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630959	386053147							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694991	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CNCCO1	InChI=1S/C20H20Cl2N4O3/c1-27-18-7-14-17(8-19(18)29-10-13-9-23-4-5-28-13)24-11-25-20(14)26-12-2-3-15(21)16(22)6-12/h2-3,6-8,11,13,23H,4-5,9-10H2,1H3,(H,24,25,26)	PRVHVZIMFXZSQV-UHFFFAOYSA-N	351424	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(morpholin-2-ylmethyl)oxy]quinazolin-4- amine::US9796704, Entry 144	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351424&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630903	386053148							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694995	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCCCN1	InChI=1S/C23H22Cl2N6O3/c1-32-19-9-14-18(27-12-28-22(14)29-13-5-6-15(24)16(25)8-13)10-20(19)33-11-21-30-23(34-31-21)17-4-2-3-7-26-17/h5-6,8-10,12,17,26H,2-4,7,11H2,1H3,(H,27,28,29)	PCRLTROAULDNDE-UHFFFAOYSA-N	351425	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piperidin-2-yl-1,2,4-oxadiazol-3- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 145	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351425&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630955	386053149							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
694999	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nsc(CN(C)C)n1	InChI=1S/C21H20Cl2N6O2S/c1-29(2)9-20-27-19(28-32-20)10-31-18-8-16-13(7-17(18)30-3)21(25-11-24-16)26-12-4-5-14(22)15(23)6-12/h4-8,11H,9-10H2,1-3H3,(H,24,25,26)	DKVQULRGPVPOGJ-UHFFFAOYSA-N	351426	N-(3,4-dichlorophenyl)-7-[({2- [(dimethylamino)methyl]-1,3-thiazol-4- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 146	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351426&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121323681	386053150							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695003	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(Cc2ccccc2)CCO1	InChI=1S/C27H26Cl2N4O3/c1-34-25-12-21-24(30-17-31-27(21)32-19-7-8-22(28)23(29)11-19)13-26(25)36-16-20-15-33(9-10-35-20)14-18-5-3-2-4-6-18/h2-8,11-13,17,20H,9-10,14-16H2,1H3,(H,30,31,32)	QUDDVDXFQIWBKM-UHFFFAOYSA-N	351427	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (phenylmethyl)morpholin-2- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 147	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802825	386053151							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695007	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCO1)C(=O)OC(C)(C)C	InChI=1S/C25H28Cl2N4O5/c1-25(2,3)36-24(32)31-7-8-34-16(12-31)13-35-22-11-20-17(10-21(22)33-4)23(29-14-28-20)30-15-5-6-18(26)19(27)9-15/h5-6,9-11,14,16H,7-8,12-13H2,1-4H3,(H,28,29,30)	QFEUXSBOVSOXOY-UHFFFAOYSA-N	351428	1,1-dimethylethyl 2-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7- yl]oxy}methyl)morpholine-4-carboxylate::US9796704, Entry 148	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802888	386053152							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695012	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nsc(CN2CCOCC2)n1	InChI=1S/C23H22Cl2N6O3S/c1-32-19-9-15-18(26-13-27-23(15)28-14-2-3-16(24)17(25)8-14)10-20(19)34-12-21-29-22(35-30-21)11-31-4-6-33-7-5-31/h2-3,8-10,13H,4-7,11-12H2,1H3,(H,26,27,28)	FRHNEIRUMPIDKL-UHFFFAOYSA-N	351429	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2- (morpholin-4-ylmethyl)-1,3-thiazol-4- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 149	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121323683	386053153							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695016	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nsc(CN2CCN(C)CC2)n1	InChI=1S/C24H25Cl2N7O2S/c1-32-5-7-33(8-6-32)12-23-30-22(31-36-23)13-35-21-11-19-16(10-20(21)34-2)24(28-14-27-19)29-15-3-4-17(25)18(26)9-15/h3-4,9-11,14H,5-8,12-13H2,1-2H3,(H,27,28,29)	HTKJGEPLONIJLG-UHFFFAOYSA-N	351430	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [(4-methylpiperazin-1-yl)methyl]-1,3-thiazol- 4-yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 150	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121323682	386053154							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695020	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C)CCO1	InChI=1S/C21H22Cl2N4O3/c1-27-5-6-29-14(10-27)11-30-20-9-18-15(8-19(20)28-2)21(25-12-24-18)26-13-3-4-16(22)17(23)7-13/h3-4,7-9,12,14H,5-6,10-11H2,1-2H3,(H,24,25,26)	QMONPAAOIIDBIL-UHFFFAOYSA-N	351431	N-(3,4-dichlorophenyl)-7-{[(4- methylmorpholin-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 151	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802820	386053155							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695024	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CNCCCO1	InChI=1S/C21H22Cl2N4O3/c1-28-19-8-15-18(9-20(19)30-11-14-10-24-5-2-6-29-14)25-12-26-21(15)27-13-3-4-16(22)17(23)7-13/h3-4,7-9,12,14,24H,2,5-6,10-11H2,1H3,(H,25,26,27)	ZPDJVHLHIVCBBN-UHFFFAOYSA-N	351432	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(1,4- oxazepan-2-ylmethyl)oxy]quinazolin-4-amine::US9796704, Entry 152	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351432&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630943	386053156							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695028	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCCNC1	InChI=1S/C23H22Cl2N6O3/c1-32-19-8-15-18(27-12-28-22(15)29-14-4-5-16(24)17(25)7-14)9-20(19)33-11-21-30-23(34-31-21)13-3-2-6-26-10-13/h4-5,7-9,12-13,26H,2-3,6,10-11H2,1H3,(H,27,28,29)	SHKAUSIXYOWPKS-UHFFFAOYSA-N	351433	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piperidin-3-yl-1,2,4-oxadiazol-3- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 153	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630953	386053157							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695032	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCCCN1C	InChI=1S/C24H24Cl2N6O3/c1-32-8-4-3-5-19(32)24-30-22(31-35-24)12-34-21-11-18-15(10-20(21)33-2)23(28-13-27-18)29-14-6-7-16(25)17(26)9-14/h6-7,9-11,13,19H,3-5,8,12H2,1-2H3,(H,27,28,29)	SUWHOJVHZNVYPL-UHFFFAOYSA-N	351434	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5- (1-methylpiperidin-2-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 154	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351434&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802803	386053158							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695037	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C)CCCO1	InChI=1S/C22H24Cl2N4O3/c1-28-6-3-7-30-15(11-28)12-31-21-10-19-16(9-20(21)29-2)22(26-13-25-19)27-14-4-5-17(23)18(24)8-14/h4-5,8-10,13,15H,3,6-7,11-12H2,1-2H3,(H,25,26,27)	ZWRRWHLGGOBSMY-UHFFFAOYSA-N	351435	N-(3,4-dichlorophenyl)-7-{[(4-methyl-1,4- oxazepan-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 155	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630944	386053159							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695041	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCCN(C)C1	InChI=1S/C24H24Cl2N6O3/c1-32-7-3-4-14(11-32)24-30-22(31-35-24)12-34-21-10-19-16(9-20(21)33-2)23(28-13-27-19)29-15-5-6-17(25)18(26)8-15/h5-6,8-10,13-14H,3-4,7,11-12H2,1-2H3,(H,27,28,29)	WUCSNTVXKXMTBP-UHFFFAOYSA-N	351436	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5- (1-methylpiperidin-3-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 156	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630954	386053160							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695045	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C(C)(C)C	InChI=1S/C22H21Cl2N5O3/c1-22(2,3)21-28-19(29-32-21)10-31-18-9-16-13(8-17(18)30-4)20(26-11-25-16)27-12-5-6-14(23)15(24)7-12/h5-9,11H,10H2,1-4H3,(H,25,26,27)	LNRUEHRMLQQRED-UHFFFAOYSA-N	351437	N-(3,4-dichlorophenyl)-7-({[5-(1,1- dimethylethyl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 157	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802787	386053161							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695049	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nsc(n1)-c1ccccc1	InChI=1S/C24H17Cl2N5O2S/c1-32-20-10-16-19(27-13-28-23(16)29-15-7-8-17(25)18(26)9-15)11-21(20)33-12-22-30-24(34-31-22)14-5-3-2-4-6-14/h2-11,13H,12H2,1H3,(H,27,28,29)	YNRDGUQMVYIVCM-UHFFFAOYSA-N	351438	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- phenyl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 158	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121323684	386053162							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695053	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cccc2nsnc12	InChI=1S/C22H15Cl2N5O2S/c1-30-19-8-14-18(25-11-26-22(14)27-13-5-6-15(23)16(24)7-13)9-20(19)31-10-12-3-2-4-17-21(12)29-32-28-17/h2-9,11H,10H2,1H3,(H,25,26,27)	HLDHNATWCDWAML-UHFFFAOYSA-N	351439	7-[(2,1,3-benzothiadiazol-4-ylmethyl)oxy]-N- (3,4-dichlorophenyl)-6-(methyloxy)quinazolin- 4-amine::US9796704, Entry 159	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351439&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802822	386053163							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695057	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(C)on1	InChI=1S/C20H16Cl2N4O3/c1-11-5-13(26-29-11)9-28-19-8-17-14(7-18(19)27-2)20(24-10-23-17)25-12-3-4-15(21)16(22)6-12/h3-8,10H,9H2,1-2H3,(H,23,24,25)	JOGJAGGMXRVDDM-UHFFFAOYSA-N	351440	N-(3,4-dichlorophenyl)-7-{[(5-methylisoxazol- 3-yl)methyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 160	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351440&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802811	386053164							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695062	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(C)c1-c1ccccc1	InChI=1S/C26H20Cl2N4O3/c1-15-25(16-6-4-3-5-7-16)22(32-35-15)13-34-24-12-21-18(11-23(24)33-2)26(30-14-29-21)31-17-8-9-19(27)20(28)10-17/h3-12,14H,13H2,1-2H3,(H,29,30,31)	ABYBLOPJBKNODK-UHFFFAOYSA-N	351441	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- methyl-4-phenylisoxazol-3- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 161	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351441	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802625	386053165							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695066	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc2ccccc2s1	InChI=1S/C23H16Cl2N4O2S/c1-30-19-9-14-18(26-12-27-23(14)28-13-6-7-15(24)16(25)8-13)10-20(19)31-11-22-29-17-4-2-3-5-21(17)32-22/h2-10,12H,11H2,1H3,(H,26,27,28)	TZOPEIOUJFXKQZ-UHFFFAOYSA-N	351442	7-[(1,3-benzothiazol-2-ylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 162	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351442	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351442&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10480426	386053166							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695070	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nonc2c1	InChI=1S/C22H15Cl2N5O3/c1-30-20-8-14-18(25-11-26-22(14)27-13-3-4-15(23)16(24)7-13)9-21(20)31-10-12-2-5-17-19(6-12)29-32-28-17/h2-9,11H,10H2,1H3,(H,25,26,27)	BDXLOYXFMUPOIW-UHFFFAOYSA-N	351443	7-[(2,1,3-benzoxadiazol-5-ylmethyl)oxy]-N- (3,4-dichlorophenyl)-6-(methyloxy)quinazolin- 4-amine::US9796704, Entry 163	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351443	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10073317	386053167							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695075	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nsc(n1)-c1cccs1	InChI=1S/C22H15Cl2N5O2S2/c1-30-17-8-13-16(25-11-26-21(13)27-12-4-5-14(23)15(24)7-12)9-18(17)31-10-20-28-22(33-29-20)19-3-2-6-32-19/h2-9,11H,10H2,1H3,(H,25,26,27)	ZJWUMNUFLUTXRN-UHFFFAOYSA-N	351444	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2- (2-thienyl)-1,3-thiazol-4- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 164	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121323685	386053168							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695080	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cnn(c1)-c1ccccc1	InChI=1S/C25H19Cl2N5O2/c1-33-23-10-19-22(28-15-29-25(19)31-17-7-8-20(26)21(27)9-17)11-24(23)34-14-16-12-30-32(13-16)18-5-3-2-4-6-18/h2-13,15H,14H2,1H3,(H,28,29,31)	KUIMRYDCYVFWRI-UHFFFAOYSA-N	351445	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(1- phenyl-1H-pyrazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 165	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10390936	386053169							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695084	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)-c1cccc(c1)C(F)(F)F	InChI=1S/C25H16Cl2F3N5O3/c1-36-20-9-16-19(31-12-32-23(16)33-15-5-6-17(26)18(27)8-15)10-21(20)37-11-22-34-24(38-35-22)13-3-2-4-14(7-13)25(28,29)30/h2-10,12H,11H2,1H3,(H,31,32,33)	LHQPNVRFCKDYKG-UHFFFAOYSA-N	351446	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({5- [3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 166	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10030748	386053170							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695088	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C25H16Cl2F3N5O3/c1-36-20-9-16-19(31-12-32-23(16)33-15-6-7-17(26)18(27)8-15)10-21(20)37-11-22-34-24(38-35-22)13-2-4-14(5-3-13)25(28,29)30/h2-10,12H,11H2,1H3,(H,31,32,33)	PTLHFHNCPGNWKH-UHFFFAOYSA-N	351447	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({5- [4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 167	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10325530	386053171							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695093	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)-c1ccc(Cl)cc1	InChI=1S/C24H16Cl3N5O3/c1-33-20-9-16-19(28-12-29-24(16)30-15-6-7-17(26)18(27)8-15)10-21(20)34-11-22-31-23(32-35-22)13-2-4-14(25)5-3-13/h2-10,12H,11H2,1H3,(H,28,29,30)	BDVHNGIDDSJCCD-UHFFFAOYSA-N	351448	7-({[3-(4-chlorophenyl)-1,2,4-oxadiazol-5- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 168	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			11756724	386053172							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695097	COc1ccc2cc(Br)ccc2c1COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3)c2cc1OC	InChI=1S/C27H20BrCl2N3O3/c1-34-24-8-3-15-9-16(28)4-6-18(15)20(24)13-36-26-12-23-19(11-25(26)35-2)27(32-14-31-23)33-17-5-7-21(29)22(30)10-17/h3-12,14H,13H2,1-2H3,(H,31,32,33)	DICBCRYPBMEARO-UHFFFAOYSA-N	351449	7-({[6-bromo-2-(methyloxy)naphthalen-1- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 169	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351449	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10077024	386053173							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695101	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cscn1	InChI=1S/C19H14Cl2N4O2S/c1-26-17-5-13-16(6-18(17)27-7-12-8-28-10-24-12)22-9-23-19(13)25-11-2-3-14(20)15(21)4-11/h2-6,8-10H,7H2,1H3,(H,22,23,25)	SHQICENFGOEXMY-UHFFFAOYSA-N	351450	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(1,3- thiazol-4-ylmethyl)oxy]quinazolin-4-amine::US9796704, Entry 170	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351450&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10455540	386053174							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695106	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc(Cl)nc1	InChI=1S/C21H15Cl3N4O2/c1-29-18-7-14-17(8-19(18)30-10-12-2-5-20(24)25-9-12)26-11-27-21(14)28-13-3-4-15(22)16(23)6-13/h2-9,11H,10H2,1H3,(H,26,27,28)	TUQBWKPRXZNXMC-UHFFFAOYSA-N	351451	7-{[(6-chloropyridin-3-yl)methyl]oxy}-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 171	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351451	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351451&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10434451	386053175							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695110	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccncc1	InChI=1S/C21H16Cl2N4O2/c1-28-19-9-15-18(10-20(19)29-11-13-4-6-24-7-5-13)25-12-26-21(15)27-14-2-3-16(22)17(23)8-14/h2-10,12H,11H2,1H3,(H,25,26,27)	DTTUCRMZJFXMJK-UHFFFAOYSA-N	351452	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(pyridin-4-ylmethyl)oxy]quinazolin-4-amine::US9796704, Entry 172	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351452&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10320305	386053176							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695115	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C)n1	InChI=1S/C20H16Cl2N4O2S/c1-11-25-13(9-29-11)8-28-19-7-17-14(6-18(19)27-2)20(24-10-23-17)26-12-3-4-15(21)16(22)5-12/h3-7,9-10H,8H2,1-2H3,(H,23,24,26)	FJUIAQIBGJSIJS-UHFFFAOYSA-N	351453	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- methyl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 173	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351453&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10026614	386053177							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695119	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(Cl)cc2COCOc12	InChI=1S/C24H18Cl3N3O4/c1-31-21-7-17-20(28-11-29-24(17)30-16-2-3-18(26)19(27)6-16)8-22(21)33-10-14-5-15(25)4-13-9-32-12-34-23(13)14/h2-8,11H,9-10,12H2,1H3,(H,28,29,30)	XUECJUQSSNVQPA-UHFFFAOYSA-N	351454	7-{[(6-chloro-4H-1,3-benzodioxin-8- yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 174	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351454&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10052331	386053178							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695123	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(Cl)n(C)nc1-c1ccccc1	InChI=1S/C26H20Cl3N5O2/c1-34-25(29)18(24(33-34)15-6-4-3-5-7-15)13-36-23-12-21-17(11-22(23)35-2)26(31-14-30-21)32-16-8-9-19(27)20(28)10-16/h3-12,14H,13H2,1-2H3,(H,30,31,32)	ZCRLDBQMLFBFFN-UHFFFAOYSA-N	351455	7-{[(5-chloro-1-methyl-3-phenyl-1H-pyrazol- 4-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 175	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351455&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347268	386053179							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695128	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1=CC2C(S1)N(C)N=C2C(F)(F)F	InChI=1S/C23H18Cl2F3N5O2S/c1-33-22-14(20(32-33)23(26,27)28)6-12(36-22)9-35-19-8-17-13(7-18(19)34-2)21(30-10-29-17)31-11-3-4-15(24)16(25)5-11/h3-8,10,14,22H,9H2,1-2H3,(H,29,30,31)	JVJKGDUZNRRKIX-UHFFFAOYSA-N	351456	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[1- methyl-3-(trifluoromethyl)-1H-thieno[2,3- c]pyrazol-5-yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 176	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351456&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10257122	386053180							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695132	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(no1)-c1ccccc1	InChI=1S/C25H18Cl2N4O3/c1-32-23-11-18-22(28-14-29-25(18)30-16-7-8-19(26)20(27)9-16)12-24(23)33-13-17-10-21(31-34-17)15-5-3-2-4-6-15/h2-12,14H,13H2,1H3,(H,28,29,30)	LUKFTCWBIWCAMK-UHFFFAOYSA-N	351457	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(3- phenylisoxazol-5-yl)methyl]oxy}quinazolin-4- amine::US9796704, Entry 177	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351457&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10413364	386053181							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695136	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(C)cc(C)cc1C	InChI=1S/C25H23Cl2N3O2/c1-14-7-15(2)19(16(3)8-14)12-32-24-11-22-18(10-23(24)31-4)25(29-13-28-22)30-17-5-6-20(26)21(27)9-17/h5-11,13H,12H2,1-4H3,(H,28,29,30)	LUJNSRUBIXBUOM-UHFFFAOYSA-N	351458	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- {[(2,4,6- trimethylphenyl)methyl]oxy}quinazolin-4- amine::US9796704, Entry 178	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351458&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10389873	386053182							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695140	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cccnc1	InChI=1S/C21H16Cl2N4O2/c1-28-19-8-15-18(9-20(19)29-11-13-3-2-6-24-10-13)25-12-26-21(15)27-14-4-5-16(22)17(23)7-14/h2-10,12H,11H2,1H3,(H,25,26,27)	LUAHOZHPDVOBIY-UHFFFAOYSA-N	351459	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(pyridin-3-ylmethyl)oxy]quinazolin-4-amine::US9796704, Entry 179	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351459&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10094017	386053183							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695144	COc1ccc(cc1)-c1cc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)on1	InChI=1S/C26H20Cl2N4O4/c1-33-17-6-3-15(4-7-17)22-10-18(36-32-22)13-35-25-12-23-19(11-24(25)34-2)26(30-14-29-23)31-16-5-8-20(27)21(28)9-16/h3-12,14H,13H2,1-2H3,(H,29,30,31)	NHCXXCMLZIJGKZ-UHFFFAOYSA-N	351460	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [4-(methyloxy)phenyl]isoxazol-5- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 180	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351460&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802618	386053184							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695148	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(Oc2ccc(Cl)cc2Cl)n(C)nc1C(F)(F)F	InChI=1S/C27H18Cl4F3N5O3/c1-39-26(42-21-6-3-13(28)7-19(21)31)16(24(38-39)27(32,33)34)11-41-23-10-20-15(9-22(23)40-2)25(36-12-35-20)37-14-4-5-17(29)18(30)8-14/h3-10,12H,11H2,1-2H3,(H,35,36,37)	GKDGCIISLGIYBM-UHFFFAOYSA-N	351461	N-(3,4-dichlorophenyl)-7-({[5-[(2,4- dichlorophenyl)oxy]-1-methyl-3- (trifluoromethyl)-1H-pyrazol-4-yl]methyl}oxy)- 6-(methyloxy)quinazolin-4-amine::US9796704, Entry 181	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351461&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10416929	386053185							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695152	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CC1	InChI=1S/C19H17Cl2N3O2/c1-25-17-7-13-16(8-18(17)26-9-11-2-3-11)22-10-23-19(13)24-12-4-5-14(20)15(21)6-12/h4-8,10-11H,2-3,9H2,1H3,(H,22,23,24)	SDPXNCYWHLAZJC-UHFFFAOYSA-N	351462	7-[(cyclopropylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 182	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351462&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802643	386053186							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695156	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CCCO1	InChI=1S/C20H19Cl2N3O3/c1-26-18-8-14-17(9-19(18)28-10-13-3-2-6-27-13)23-11-24-20(14)25-12-4-5-15(21)16(22)7-12/h4-5,7-9,11,13H,2-3,6,10H2,1H3,(H,23,24,25)	QNPKKOXYJDZPQK-UHFFFAOYSA-N	351463	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(tetrahydrofuran-2-ylmethyl)oxy]quinazolin- 4-amine::US9796704, Entry 183	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351463&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802908	386053187							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695161	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1CCCC1	InChI=1S/C20H19Cl2N3O2/c1-26-18-9-14-17(10-19(18)27-13-4-2-3-5-13)23-11-24-20(14)25-12-6-7-15(21)16(22)8-12/h6-11,13H,2-5H2,1H3,(H,23,24,25)	VOQVXZHQBTXEHV-UHFFFAOYSA-N	351464	7-(cyclopentyloxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 184	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351464	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351464&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802785	386053188							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695165	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CCCCC1	InChI=1S/C23H25Cl2N3O2/c1-29-21-12-17-20(13-22(21)30-10-9-15-5-3-2-4-6-15)26-14-27-23(17)28-16-7-8-18(24)19(25)11-16/h7-8,11-15H,2-6,9-10H2,1H3,(H,26,27,28)	WYZCWZRHCBLLRQ-UHFFFAOYSA-N	351465	7-[(2-cyclohexylethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 185	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351465&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10095075	386053189							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695169	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CCCCC1	InChI=1S/C22H23Cl2N3O2/c1-28-20-10-16-19(11-21(20)29-12-14-5-3-2-4-6-14)25-13-26-22(16)27-15-7-8-17(23)18(24)9-15/h7-11,13-14H,2-6,12H2,1H3,(H,25,26,27)	GYWNYPUPJODCTA-UHFFFAOYSA-N	351466	7-[(cyclohexylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 186	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351466&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802557	386053190							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695173	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CCC1	InChI=1S/C20H19Cl2N3O2/c1-26-18-8-14-17(9-19(18)27-10-12-3-2-4-12)23-11-24-20(14)25-13-5-6-15(21)16(22)7-13/h5-9,11-12H,2-4,10H2,1H3,(H,23,24,25)	GOTKNVOMZNDPKT-UHFFFAOYSA-N	351467	7-[(cyclobutylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 187	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351467&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802873	386053191							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695178	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1OCCO1	InChI=1S/C20H19Cl2N3O4/c1-26-17-9-13-16(10-18(17)27-5-4-19-28-6-7-29-19)23-11-24-20(13)25-12-2-3-14(21)15(22)8-12/h2-3,8-11,19H,4-7H2,1H3,(H,23,24,25)	LDVUSEWLJKUPMB-UHFFFAOYSA-N	351468	N-(3,4-dichlorophenyl)-7-{[2-(1,3-dioxolan-2- yl)ethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 188	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351468&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10455667	386053192							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695182	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1OCCCO1	InChI=1S/C21H21Cl2N3O4/c1-27-18-10-14-17(11-19(18)28-8-5-20-29-6-2-7-30-20)24-12-25-21(14)26-13-3-4-15(22)16(23)9-13/h3-4,9-12,20H,2,5-8H2,1H3,(H,24,25,26)	KBVAWHBMEYHTMD-UHFFFAOYSA-N	351469	N-(3,4-dichlorophenyl)-7-{[2-(1,3-dioxan-2- yl)ethyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 189	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351469&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802898	386053193							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695186	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCN1CCOCC1	InChI=1S/C21H22Cl2N4O3/c1-28-19-11-15-18(12-20(19)30-9-6-27-4-7-29-8-5-27)24-13-25-21(15)26-14-2-3-16(22)17(23)10-14/h2-3,10-13H,4-9H2,1H3,(H,24,25,26)	FAJVOBZBVGQKFD-UHFFFAOYSA-N	351470	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- morpholin-4-ylethyl)oxy]quinazolin-4-amine::US9796704, Entry 190	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351470&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802664	386053194							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695190	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCN1CCCC1	InChI=1S/C21H22Cl2N4O2/c1-28-19-11-15-18(12-20(19)29-9-8-27-6-2-3-7-27)24-13-25-21(15)26-14-4-5-16(22)17(23)10-14/h4-5,10-13H,2-3,6-9H2,1H3,(H,24,25,26)	INTICWGTKLQPSH-UHFFFAOYSA-N	351471	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- pyrrolidin-1-ylethyl)oxy]quinazolin-4-amine::US9796704, Entry 191	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351471&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802728	386053195							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695194	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCN1CCCCC1	InChI=1S/C22H24Cl2N4O2/c1-29-20-12-16-19(13-21(20)30-10-9-28-7-3-2-4-8-28)25-14-26-22(16)27-15-5-6-17(23)18(24)11-15/h5-6,11-14H,2-4,7-10H2,1H3,(H,25,26,27)	QOLKGXDWVMWHLS-UHFFFAOYSA-N	351472	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- piperidin-1-ylethyl)oxy]quinazolin-4-amine::US9796704, Entry 192	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351472&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802796	386053196							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695198	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCN1C(=O)c2ccccc2C1=O	InChI=1S/C25H18Cl2N4O4/c1-34-21-11-17-20(28-13-29-23(17)30-14-6-7-18(26)19(27)10-14)12-22(21)35-9-8-31-24(32)15-4-2-3-5-16(15)25(31)33/h2-7,10-13H,8-9H2,1H3,(H,28,29,30)	KCGTXHCPPMDHIJ-UHFFFAOYSA-N	351473	2-(2-{[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}ethyl)-1H- isoindole-1,3(2H)-dione::US9796704, Entry 193	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351473&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802754	386053197							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695203	CO[C@@H]1O[C@@H](COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)[C@H](O)[C@@H](O)[C@@H]1O	InChI=1S/C22H23Cl2N3O7/c1-31-15-6-11-14(25-9-26-21(11)27-10-3-4-12(23)13(24)5-10)7-16(15)33-8-17-18(28)19(29)20(30)22(32-2)34-17/h3-7,9,17-20,22,28-30H,8H2,1-2H3,(H,25,26,27)/t17-,18-,19+,20-,22+/m0/s1	JFXUNTVGMAFDCX-SXFAUFNYSA-N	351474	US9796704, Entry 194::methyl 6-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-alpha-D- glucopyranoside	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351474&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802800	386053198							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695207	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC(=O)N1CCOCC1	InChI=1S/C21H20Cl2N4O4/c1-29-18-9-14-17(10-19(18)31-11-20(28)27-4-6-30-7-5-27)24-12-25-21(14)26-13-2-3-15(22)16(23)8-13/h2-3,8-10,12H,4-7,11H2,1H3,(H,24,25,26)	KCIJBEJQKOVUTG-UHFFFAOYSA-N	351475	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- morpholin-4-yl-2-oxoethyl)oxy]quinazolin-4- amine::US9796704, Entry 195	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351475&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802688	386053199							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695211	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCCCN1C(=O)OC(C)(C)C	InChI=1S/C28H30Cl2N6O5/c1-28(2,3)40-27(37)36-10-6-5-7-21(36)26-34-24(35-41-26)14-39-23-13-20-17(12-22(23)38-4)25(32-15-31-20)33-16-8-9-18(29)19(30)11-16/h8-9,11-13,15,21H,5-7,10,14H2,1-4H3,(H,31,32,33)	RUBSXJGCJAOKHK-UHFFFAOYSA-N	351476	1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,2,4- oxadiazol-5-yl]piperidine-1-carboxylate::US9796704, Entry 196	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351476&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802717	386053200							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695216	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C28H30Cl2N6O5/c1-28(2,3)40-27(37)36-9-7-16(8-10-36)26-34-24(35-41-26)14-39-23-13-21-18(12-22(23)38-4)25(32-15-31-21)33-17-5-6-19(29)20(30)11-17/h5-6,11-13,15-16H,7-10,14H2,1-4H3,(H,31,32,33)	SYYMSDGOIXLMBC-UHFFFAOYSA-N	351477	1,1-dimethylethyl 4-[3-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,2,4- oxadiazol-5-yl]piperidine-1-carboxylate::US9796704, Entry 197	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351477&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802886	386053201							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695220	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(cs1)-c1ccc(cc1)N1CCCC1	InChI=1S/C29H25Cl2N5O2S/c1-37-26-13-21-24(32-17-33-29(21)34-19-6-9-22(30)23(31)12-19)14-27(26)38-15-28-35-25(16-39-28)18-4-7-20(8-5-18)36-10-2-3-11-36/h4-9,12-14,16-17H,2-3,10-11,15H2,1H3,(H,32,33,34)	LARWQCXRXJJFLU-UHFFFAOYSA-N	351478	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-pyrrolidin-1-ylphenyl)-1,3-thiazol-2- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 198	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351478&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802647	386053202							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695225	CCN(CC)c1ccc(cc1)-c1csc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)n1	InChI=1S/C29H27Cl2N5O2S/c1-4-36(5-2)20-9-6-18(7-10-20)25-16-39-28(35-25)15-38-27-14-24-21(13-26(27)37-3)29(33-17-32-24)34-19-8-11-22(30)23(31)12-19/h6-14,16-17H,4-5,15H2,1-3H3,(H,32,33,34)	XCMSAHCDUHXACI-UHFFFAOYSA-N	351479	N-(3,4-dichlorophenyl)-7-[({4-[4- (diethylamino)phenyl]-1,3-thiazol-2- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 199	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351479&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802865	386053203							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695230	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(cs1)-c1ccc(O)c(c1)C(N)=O	InChI=1S/C26H19Cl2N5O4S/c1-36-22-8-15-19(30-12-31-26(15)32-14-3-4-17(27)18(28)7-14)9-23(22)37-10-24-33-20(11-38-24)13-2-5-21(34)16(6-13)25(29)35/h2-9,11-12,34H,10H2,1H3,(H2,29,35)(H,30,31,32)	VATKWVNDCITFEB-UHFFFAOYSA-N	351480	5-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,3- thiazol-4-yl]-2-hydroxybenzamide::US9796704, Entry 200	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351480&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802672	386053204							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695234	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(cs1)-c1cccnc1	InChI=1S/C24H17Cl2N5O2S/c1-32-21-8-16-19(28-13-29-24(16)30-15-4-5-17(25)18(26)7-15)9-22(21)33-11-23-31-20(12-34-23)14-3-2-6-27-10-14/h2-10,12-13H,11H2,1H3,(H,28,29,30)	HSVSYWHNTHEXTN-UHFFFAOYSA-N	351481	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- pyridin-3-yl-1,3-thiazol-2- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 201	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351481&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802575	386053205							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695238	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(cs1)-c1ccccn1	InChI=1S/C24H17Cl2N5O2S/c1-32-21-9-15-19(28-13-29-24(15)30-14-5-6-16(25)17(26)8-14)10-22(21)33-11-23-31-20(12-34-23)18-4-2-3-7-27-18/h2-10,12-13H,11H2,1H3,(H,28,29,30)	JFLJVHMCZLMBSN-UHFFFAOYSA-N	351482	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- pyridin-2-yl-1,3-thiazol-2- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 202	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351482&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802700	386053206							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695243	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(cs1)-c1ccncc1	InChI=1S/C24H17Cl2N5O2S/c1-32-21-9-16-19(28-13-29-24(16)30-15-2-3-17(25)18(26)8-15)10-22(21)33-11-23-31-20(12-34-23)14-4-6-27-7-5-14/h2-10,12-13H,11H2,1H3,(H,28,29,30)	VRXGZDANOSIHSR-UHFFFAOYSA-N	351483	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- pyridin-4-yl-1,3-thiazol-2- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 203	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351483&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802769	386053207							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695248	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)N1CCOCC1	InChI=1S/C23H21Cl2N5O3S/c1-31-20-9-16-19(26-13-27-22(16)28-14-2-3-17(24)18(25)8-14)10-21(20)33-11-15-12-34-23(29-15)30-4-6-32-7-5-30/h2-3,8-10,12-13H,4-7,11H2,1H3,(H,26,27,28)	ZHMULGIXCIACTQ-UHFFFAOYSA-N	351484	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- morpholin-4-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 204	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351484&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802862	386053208							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695253	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)N1CCOCC1	InChI=1S/C22H20Cl2N6O4/c1-31-18-9-14-17(25-12-26-21(14)27-13-2-3-15(23)16(24)8-13)10-19(18)33-11-20-28-22(29-34-20)30-4-6-32-7-5-30/h2-3,8-10,12H,4-7,11H2,1H3,(H,25,26,27)	DACWWGSNTVRALQ-UHFFFAOYSA-N	351485	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(3- morpholin-4-yl-1,2,4-oxadiazol-5- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 205	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351485&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802875	386053209							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695257	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)N(C)C	InChI=1S/C20H18Cl2N6O3/c1-28(2)20-26-18(31-27-20)9-30-17-8-15-12(7-16(17)29-3)19(24-10-23-15)25-11-4-5-13(21)14(22)6-11/h4-8,10H,9H2,1-3H3,(H,23,24,25)	QJMKYRIHQWAKSM-UHFFFAOYSA-N	351486	N-(3,4-dichlorophenyl)-7-({[3- (dimethylamino)-1,2,4-oxadiazol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 206	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351486&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802599	386053210							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695261	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCN(C)CC2)cs1	InChI=1S/C25H26Cl2N6O2S/c1-32-5-7-33(8-6-32)12-17-14-36-24(30-17)13-35-23-11-21-18(10-22(23)34-2)25(29-15-28-21)31-16-3-4-19(26)20(27)9-16/h3-4,9-11,14-15H,5-8,12-13H2,1-2H3,(H,28,29,31)	AYWUHPUXKGVOSD-UHFFFAOYSA-N	351487	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4- [(4-methylpiperazin-1-yl)methyl]-1,3-thiazol- 2-yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 207	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351487&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802907	386053211							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695266	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc2CCNCc2s1	InChI=1S/C22H19Cl2N5O2S/c1-30-18-7-13-17(26-11-27-22(13)28-12-2-3-14(23)15(24)6-12)8-19(18)31-10-21-29-16-4-5-25-9-20(16)32-21/h2-3,6-8,11,25H,4-5,9-10H2,1H3,(H,26,27,28)	WVCAYXOTVLLXMU-UHFFFAOYSA-N	351488	N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin- 2-ylmethyl)oxy]quinazolin-4-amine::US9796704, Entry 208	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351488&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630967	386053212							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695270	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCOCC2)cs1	InChI=1S/C24H23Cl2N5O3S/c1-32-21-9-17-20(27-14-28-24(17)30-15-2-3-18(25)19(26)8-15)10-22(21)34-12-23-29-16(13-35-23)11-31-4-6-33-7-5-31/h2-3,8-10,13-14H,4-7,11-12H2,1H3,(H,27,28,30)	FTIMKXNADWOPKE-UHFFFAOYSA-N	351489	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (morpholin-4-ylmethyl)-1,3-thiazol-2- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 209	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351489&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802706	386053213							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695274	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCCN(C)CC2)cs1	InChI=1S/C26H28Cl2N6O2S/c1-33-6-3-7-34(9-8-33)13-18-15-37-25(31-18)14-36-24-12-22-19(11-23(24)35-2)26(30-16-29-22)32-17-4-5-20(27)21(28)10-17/h4-5,10-12,15-16H,3,6-9,13-14H2,1-2H3,(H,29,30,32)	FMLKNZKLRJRZQJ-UHFFFAOYSA-N	351490	N-(3,4-dichlorophenyl)-7-[({4-[(4-methyl-1,4- diazepan-1-yl)methyl]-1,3-thiazol-2- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 210	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351490&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802716	386053214							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695278	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(COCc2ccccc2)n1	InChI=1S/C26H21Cl2N5O4/c1-34-22-10-18-21(29-15-30-26(18)31-17-7-8-19(27)20(28)9-17)11-23(22)36-13-24-32-25(37-33-24)14-35-12-16-5-3-2-4-6-16/h2-11,15H,12-14H2,1H3,(H,29,30,31)	NVKZQTWUWKWYCG-UHFFFAOYSA-N	351491	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- {[(phenylmethyl)oxy]methyl}-1,2,4-oxadiazol- 3-yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 211	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351491&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802724	386053215							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695282	CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1	InChI=1S/C22H24Cl2N4O3/c1-3-28-6-7-30-15(11-28)12-31-21-10-19-16(9-20(21)29-2)22(26-13-25-19)27-14-4-5-17(23)18(24)8-14/h4-5,8-10,13,15H,3,6-7,11-12H2,1-2H3,(H,25,26,27)	HMNGFRURISAKFO-UHFFFAOYSA-N	351492	N-(3,4-dichlorophenyl)-7-{[(4-ethylmorpholin- 2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 212	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351492&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802737	386053216							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695286	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)C1CCNCC1	InChI=1S/C24H23Cl2N5O2S/c1-32-21-9-17-20(28-13-29-23(17)30-15-2-3-18(25)19(26)8-15)10-22(21)33-11-16-12-34-24(31-16)14-4-6-27-7-5-14/h2-3,8-10,12-14,27H,4-7,11H2,1H3,(H,28,29,30)	NYIGUQNAOHAUFR-UHFFFAOYSA-N	351493	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-4-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 213	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351493&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			53630972	386053217							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695290	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)C1CCN(C)CC1	InChI=1S/C25H25Cl2N5O2S/c1-32-7-5-15(6-8-32)25-31-17(13-35-25)12-34-23-11-21-18(10-22(23)33-2)24(29-14-28-21)30-16-3-4-19(26)20(27)9-16/h3-4,9-11,13-15H,5-8,12H2,1-2H3,(H,28,29,30)	IQEZRSQHZBKCOU-UHFFFAOYSA-N	351494	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2- (1-methylpiperidin-4-yl)-1,3-thiazol-4- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 214	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351494&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802861	386053218							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695294	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C27H29Cl2N7O5/c1-27(2,3)40-26(37)36-9-7-35(8-10-36)25-33-23(41-34-25)14-39-22-13-20-17(12-21(22)38-4)24(31-15-30-20)32-16-5-6-18(28)19(29)11-16/h5-6,11-13,15H,7-10,14H2,1-4H3,(H,30,31,32)	VVDWMCFFRNYWGL-UHFFFAOYSA-N	351495	1,1-dimethylethyl 4-[5-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,2,4- oxadiazol-3-yl]piperazine-1-carboxylate::US9796704, Entry 215	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351495&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802714	386053219							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695299	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)N1CCNCC1	InChI=1S/C22H21Cl2N7O3/c1-32-18-9-14-17(26-12-27-21(14)28-13-2-3-15(23)16(24)8-13)10-19(18)33-11-20-29-22(30-34-20)31-6-4-25-5-7-31/h2-3,8-10,12,25H,4-7,11H2,1H3,(H,26,27,28)	XRTAZINADDFLOG-UHFFFAOYSA-N	351496	US9796704, Entry 216::[(1E)-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351496&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802679	386053220							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695304	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)N1CCCC1	InChI=1S/C22H20Cl2N6O3/c1-31-18-9-14-17(25-12-26-21(14)27-13-4-5-15(23)16(24)8-13)10-19(18)32-11-20-28-22(29-33-20)30-6-2-3-7-30/h4-5,8-10,12H,2-3,6-7,11H2,1H3,(H,25,26,27)	MLXXNWHIZCXWDE-UHFFFAOYSA-N	351497	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(3- piperazin-1-yl-1,2,4-oxadiazol-5- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 217	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351497&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			139208796	386053221							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695309	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)N1CCN(C)CC1	InChI=1S/C23H23Cl2N7O3/c1-31-5-7-32(8-6-31)23-29-21(35-30-23)12-34-20-11-18-15(10-19(20)33-2)22(27-13-26-18)28-14-3-4-16(24)17(25)9-14/h3-4,9-11,13H,5-8,12H2,1-2H3,(H,26,27,28)	UNVZWJFKXAEDKM-UHFFFAOYSA-N	351498	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[3- (4-methylpiperazin-1-yl)-1,2,4-oxadiazol-5- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 218	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351498&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802605	386053222							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695313	CCN1CCCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1	InChI=1S/C25H26Cl2N6O3/c1-3-33-9-5-4-6-20(33)25-31-23(32-36-25)13-35-22-12-19-16(11-21(22)34-2)24(29-14-28-19)30-15-7-8-17(26)18(27)10-15/h7-8,10-12,14,20H,3-6,9,13H2,1-2H3,(H,28,29,30)	VYVLFCZOKFCBJQ-UHFFFAOYSA-N	351499	N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-2-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 219	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351499&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802919	386053223							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695317	CCN1CCN(CC1)c1noc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)n1	InChI=1S/C24H25Cl2N7O3/c1-3-32-6-8-33(9-7-32)24-30-22(36-31-24)13-35-21-12-19-16(11-20(21)34-2)23(28-14-27-19)29-15-4-5-17(25)18(26)10-15/h4-5,10-12,14H,3,6-9,13H2,1-2H3,(H,27,28,29)	FGHXOSBHGQKMBX-UHFFFAOYSA-N	351500	N-(3,4-dichlorophenyl)-7-({[3-(4- ethylpiperazin-1-yl)-1,2,4-oxadiazol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 220	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351500&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802773	386053224							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695321	COC1=CC=[N](C=C1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1	InChI=1S/C24H19Cl2N6O4/c1-33-15-5-7-32(8-6-15)24-30-22(31-36-24)12-35-21-11-19-16(10-20(21)34-2)23(28-13-27-19)29-14-3-4-17(25)18(26)9-14/h3-11,13H,12H2,1-2H3,(H,27,28,29)	QSMNHXGXWWZHHE-UHFFFAOYSA-N	351501	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({5- [4-(methyloxy)phenyl]-1,2,4-oxadiazol-3- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 221	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351501&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			139208797	386053225							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695325	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C26H17Cl2F3N4O2S/c1-36-22-9-18-21(32-13-33-24(18)34-16-6-7-19(27)20(28)8-16)10-23(22)37-11-17-12-38-25(35-17)14-2-4-15(5-3-14)26(29,30)31/h2-10,12-13H,11H2,1H3,(H,32,33,34)	RSQKKUZJTBAHBG-UHFFFAOYSA-N	351502	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [4-(trifluoromethyl)phenyl]-1,3-thiazol-4- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 222	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351502&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802718	386053226							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695330	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)-c1ccc(Cl)cc1	InChI=1S/C25H17Cl3N4O2S/c1-33-22-9-18-21(29-13-30-24(18)31-16-6-7-19(27)20(28)8-16)10-23(22)34-11-17-12-35-25(32-17)14-2-4-15(26)5-3-14/h2-10,12-13H,11H2,1H3,(H,29,30,31)	KIHIMMDNUNDKTJ-UHFFFAOYSA-N	351503	7-({[2-(4-chlorophenyl)-1,3-thiazol-4- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 223	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351503&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802553	386053227							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695335	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)-c1c(C)noc1C	InChI=1S/C23H18Cl2N6O4/c1-11-21(12(2)34-30-11)23-29-20(31-35-23)9-33-19-8-17-14(7-18(19)32-3)22(27-10-26-17)28-13-4-5-15(24)16(25)6-13/h4-8,10H,9H2,1-3H3,(H,26,27,28)	NQWKXHZZPBXKGF-UHFFFAOYSA-N	351504	N-(3,4-dichlorophenyl)-7-({[5-(3,5- dimethylisoxazol-4-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 224	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351504&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802559	386053228							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695340	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc2ccc(Cl)cc12	InChI=1S/C24H16Cl3N3O2S/c1-31-21-8-17-20(28-12-29-24(17)30-15-3-4-18(26)19(27)7-15)9-22(21)32-10-13-11-33-23-5-2-14(25)6-16(13)23/h2-9,11-12H,10H2,1H3,(H,28,29,30)	QQGZOWNAHJAXCG-UHFFFAOYSA-N	351505	7-{[(5-chloro-1-benzothien-3-yl)methyl]oxy}- N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 225	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351505&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802665	386053229							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695345	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)-c1ccc(cc1)C(C)(C)C	InChI=1S/C28H25Cl2N5O3/c1-28(2,3)17-7-5-16(6-8-17)26-34-25(38-35-26)14-37-24-13-22-19(12-23(24)36-4)27(32-15-31-22)33-18-9-10-20(29)21(30)11-18/h5-13,15H,14H2,1-4H3,(H,31,32,33)	ZBNFVHQEUFIFJM-UHFFFAOYSA-N	351506	N-(3,4-dichlorophenyl)-7-[({3-[4-(1,1- dimethylethyl)phenyl]-1,2,4-oxadiazol-5- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 226	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351506&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802863	386053230							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695350	COc1ccccc1-c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1	InChI=1S/C25H19Cl2N5O4/c1-33-20-6-4-3-5-15(20)25-31-23(32-36-25)12-35-22-11-19-16(10-21(22)34-2)24(29-13-28-19)30-14-7-8-17(26)18(27)9-14/h3-11,13H,12H2,1-2H3,(H,28,29,30)	DTMZOKHWEQAEJP-UHFFFAOYSA-N	351507	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({5- [2-(methyloxy)phenyl]-1,2,4-oxadiazol-3- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 227	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351507&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802595	386053231							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695355	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nnc(o1)-c1ccc(C)cc1	InChI=1S/C25H19Cl2N5O3/c1-14-3-5-15(6-4-14)25-32-31-23(35-25)12-34-22-11-20-17(10-21(22)33-2)24(29-13-28-20)30-16-7-8-18(26)19(27)9-16/h3-11,13H,12H2,1-2H3,(H,28,29,30)	ZNOFYQJDWNDHAI-UHFFFAOYSA-N	351508	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5- (4-methylphenyl)-1,3,4-oxadiazol-2- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 228	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351508&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802770	386053232							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695360	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nccn1Cc1ccccc1	InChI=1S/C26H21Cl2N5O2/c1-34-23-12-19-22(30-16-31-26(19)32-18-7-8-20(27)21(28)11-18)13-24(23)35-15-25-29-9-10-33(25)14-17-5-3-2-4-6-17/h2-13,16H,14-15H2,1H3,(H,30,31,32)	PVTTWYOJLADNCZ-UHFFFAOYSA-N	351509	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[1- (phenylmethyl)-lH-imidazol-2- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 229	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351509&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802826	386053233							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695365	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(C)onc1-c1c(Cl)cccc1Cl	InChI=1S/C26H18Cl4N4O3/c1-13-16(25(34-37-13)24-18(28)4-3-5-19(24)29)11-36-23-10-21-15(9-22(23)35-2)26(32-12-31-21)33-14-6-7-17(27)20(30)8-14/h3-10,12H,11H2,1-2H3,(H,31,32,33)	AHIOWTSQFILAEW-UHFFFAOYSA-N	351510	N-(3,4-dichlorophenyl)-7-({[3-(2,6- dichlorophenyl)-5-methylisoxazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 230	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351510&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802839	386053234							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695370	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(F)cc2OCCOc12	InChI=1S/C24H18Cl2FN3O4/c1-31-20-9-16-19(28-12-29-24(16)30-15-2-3-17(25)18(26)8-15)10-21(20)34-11-13-6-14(27)7-22-23(13)33-5-4-32-22/h2-3,6-10,12H,4-5,11H2,1H3,(H,28,29,30)	ZMGKRGOCDQRNTB-UHFFFAOYSA-N	351511	N-(3,4-dichlorophenyl)-7-{[(6-fluoro-4H-1,3- benzodioxin-8-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 231	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351511&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			121323686	386053235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695375	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(Br)cc(Br)c1	InChI=1S/C22H15Br2Cl2N3O2/c1-30-20-8-16-19(9-21(20)31-10-12-4-13(23)6-14(24)5-12)27-11-28-22(16)29-15-2-3-17(25)18(26)7-15/h2-9,11H,10H2,1H3,(H,27,28,29)	YETQQFMHUDZVIA-UHFFFAOYSA-N	351512	7-{[(3,5-dibromophenyl)methyl]oxy}-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 232	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351512&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802646	386053236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695380	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(F)cccc1F	InChI=1S/C22H15Cl2F2N3O2/c1-30-20-8-13-19(9-21(20)31-10-14-17(25)3-2-4-18(14)26)27-11-28-22(13)29-12-5-6-15(23)16(24)7-12/h2-9,11H,10H2,1H3,(H,27,28,29)	WGVZZDSXBCCRPN-UHFFFAOYSA-N	351513	N-(3,4-dichlorophenyl)-7-{[(2,6- difluorophenyl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 233	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351513&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802564	386053237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695385	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1=N[N](CS(=O)(=O)c2ccccn2)=CO1	InChI=1S/C24H19Cl2N6O5S/c1-35-20-9-16-19(28-12-29-24(16)30-15-5-6-17(25)18(26)8-15)10-21(20)36-11-22-31-32(13-37-22)14-38(33,34)23-4-2-3-7-27-23/h2-10,12-13H,11,14H2,1H3,(H,28,29,30)	YUHWJTGCNDMHMW-UHFFFAOYSA-N	351514	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(pyridin-2-ylsulfonyl)methyl]-1,2,4-oxadiazol- 5-yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 234	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351514&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			139208798	386053238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695390	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)-c1ccccc1	InChI=1S/C24H17Cl2N5O3/c1-32-20-10-16-19(27-13-28-23(16)29-15-7-8-17(25)18(26)9-15)11-21(20)33-12-22-30-24(34-31-22)14-5-3-2-4-6-14/h2-11,13H,12H2,1H3,(H,27,28,29)	ABQLLFONNKQLLB-UHFFFAOYSA-N	351515	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- phenyl-1,2,4-oxadiazol-3- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 235	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351515&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802731	386053239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695395	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(cc(Cl)c2c1)C(F)(F)F	InChI=1S/C26H16Cl3F3N4O2/c1-37-22-8-16-21(33-12-34-25(16)35-14-3-4-17(27)19(29)7-14)10-23(22)38-11-13-2-5-20-15(6-13)18(28)9-24(36-20)26(30,31)32/h2-10,12H,11H2,1H3,(H,33,34,35)	QEIAACVSNFOMGZ-UHFFFAOYSA-N	351516	7-({[4-chloro-2-(trifluoromethyl)quinolin-6- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 236	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351516&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802631	386053240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695400	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CCCN1C	InChI=1S/C22H24Cl2N4O2/c1-28-8-3-4-15(28)7-9-30-21-12-19-16(11-20(21)29-2)22(26-13-25-19)27-14-5-6-17(23)18(24)10-14/h5-6,10-13,15H,3-4,7-9H2,1-2H3,(H,25,26,27)	YAEMBTULTQVMDI-UHFFFAOYSA-N	351517	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[2- (1-methylpyrrolidin-2-yl)ethyl]oxy}quinazolin- 4-amine::US9796704, Entry 237	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351517&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802666	386053241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695405	CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1	InChI=1S/C25H26Cl2N6O3/c1-3-33-8-6-15(7-9-33)25-31-23(32-36-25)13-35-22-12-20-17(11-21(22)34-2)24(29-14-28-20)30-16-4-5-18(26)19(27)10-16/h4-5,10-12,14-15H,3,6-9,13H2,1-2H3,(H,28,29,30)	QWTRRGLWVSSIML-UHFFFAOYSA-N	351518	N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 238	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351518&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58013796	386053242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695410	CCN1CCCC(C1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1	InChI=1S/C25H26Cl2N6O3/c1-3-33-8-4-5-15(12-33)25-31-23(32-36-25)13-35-22-11-20-17(10-21(22)34-2)24(29-14-28-20)30-16-6-7-18(26)19(27)9-16/h6-7,9-11,14-15H,3-5,8,12-13H2,1-2H3,(H,28,29,30)	GCBUMMPSFVNQKY-UHFFFAOYSA-N	351519	N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-3-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 239	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351519&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			58013772	386053243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695415	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)N(C)C	InChI=1S/C21H19Cl2N5O2S/c1-28(2)21-27-13(10-31-21)9-30-19-8-17-14(7-18(19)29-3)20(25-11-24-17)26-12-4-5-15(22)16(23)6-12/h4-8,10-11H,9H2,1-3H3,(H,24,25,26)	DGOBVCDUGLUZMU-UHFFFAOYSA-N	351520	N-(3,4-dichlorophenyl)-7-({[2- (dimethylamino)-1,3-thiazol-4-yl]methyl}oxy)- 6-(methyloxy)quinazolin-4-amine::US9796704, Entry 240	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351520&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802663	386053244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695420	CCN1CCCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1	InChI=1S/C23H26Cl2N4O3/c1-3-29-7-4-8-31-16(12-29)13-32-22-11-20-17(10-21(22)30-2)23(27-14-26-20)28-15-5-6-18(24)19(25)9-15/h5-6,9-11,14,16H,3-4,7-8,12-13H2,1-2H3,(H,26,27,28)	BZLNIUFWAWPNOW-UHFFFAOYSA-N	351521	N-(3,4-dichlorophenyl)-7-{[(4-ethyl-1,4- oxazepan-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 241	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351521&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802623	386053245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695425	CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1	InChI=1S/C26H27Cl2N5O2S/c1-3-33-8-6-16(7-9-33)26-32-18(14-36-26)13-35-24-12-22-19(11-23(24)34-2)25(30-15-29-22)31-17-4-5-20(27)21(28)10-17/h4-5,10-12,14-16H,3,6-9,13H2,1-2H3,(H,29,30,31)	KJLBXUKNKUWCED-UHFFFAOYSA-N	351522	N-(3,4-dichlorophenyl)-7-({[2-(1- ethylpiperidin-4-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 242	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351522&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802563	386053246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695430	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)C1CCCN1	InChI=1S/C22H20Cl2N6O3/c1-31-18-8-13-17(26-11-27-21(13)28-12-4-5-14(23)15(24)7-12)9-19(18)32-10-20-29-22(30-33-20)16-3-2-6-25-16/h4-5,7-9,11,16,25H,2-3,6,10H2,1H3,(H,26,27,28)	HFDJFCJNMFTWOT-UHFFFAOYSA-N	351523	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(2S)-pyrrolidin-2-yl]-1,2,4-oxadiazol-5- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 243	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351523&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			76614830	386053247							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695435	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)C1CCCN1	InChI=1S/C23H21Cl2N5O2S/c1-31-20-8-15-19(27-12-28-22(15)29-13-4-5-16(24)17(25)7-13)9-21(20)32-10-14-11-33-23(30-14)18-3-2-6-26-18/h4-5,7-9,11-12,18,26H,2-3,6,10H2,1H3,(H,27,28,29)	UJKCNZDTMJJLEP-UHFFFAOYSA-N	351524	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [(2S)-pyrrolidin-2-yl]-1,3-thiazol-4- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 244	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351524&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69026545	386053248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695440	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(COC(=O)c2ccccc2)n1	InChI=1S/C27H20Cl2N4O4S/c1-35-23-10-19-22(30-15-31-26(19)33-17-7-8-20(28)21(29)9-17)11-24(23)36-12-18-14-38-25(32-18)13-37-27(34)16-5-3-2-4-6-16/h2-11,14-15H,12-13H2,1H3,(H,30,31,33)	SROSEDFOBYVYCH-UHFFFAOYSA-N	351525	US9796704, Entry 245::[4-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,3- thiazol-2-yl]methyl benzoate	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351525&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802774	386053249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695445	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(CO)n1	InChI=1S/C20H16Cl2N4O3S/c1-28-17-5-13-16(6-18(17)29-8-12-9-30-19(7-27)25-12)23-10-24-20(13)26-11-2-3-14(21)15(22)4-11/h2-6,9-10,27H,7-8H2,1H3,(H,23,24,26)	ATNQJIZWZJGBST-UHFFFAOYSA-N	351526	US9796704, Entry 246::[4-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,3- thiazol-2-yl]methanol	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351526&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802673	386053250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695450	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc2CC(C)NCc2s1	InChI=1S/C23H21Cl2N5O2S/c1-12-5-18-21(9-26-12)33-22(30-18)10-32-20-8-17-14(7-19(20)31-2)23(28-11-27-17)29-13-3-4-15(24)16(25)6-13/h3-4,6-8,11-12,26H,5,9-10H2,1-2H3,(H,27,28,29)	FYJMEEVVSSJUMQ-UHFFFAOYSA-N	351527	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4- c]pyridin-2-yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 247	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351527&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802891	386053251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695455	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)[C@@H]1CSCN1	InChI=1S/C22H19Cl2N5O2S2/c1-30-19-5-14-17(25-10-26-21(14)28-12-2-3-15(23)16(24)4-12)6-20(19)31-7-13-8-33-22(29-13)18-9-32-11-27-18/h2-6,8,10,18,27H,7,9,11H2,1H3,(H,25,26,28)/t18-/m0/s1	BYRDCUSCDUCHLA-SFHVURJKSA-N	351528	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [(4S)-1,3-thiazolidin-4-yl]-1,3-thiazol-4- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 248	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351528&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802753	386053252							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695460	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)C1CCCCN1	InChI=1S/C24H23Cl2N5O2S/c1-32-21-9-16-20(28-13-29-23(16)30-14-5-6-17(25)18(26)8-14)10-22(21)33-11-15-12-34-24(31-15)19-4-2-3-7-27-19/h5-6,8-10,12-13,19,27H,2-4,7,11H2,1H3,(H,28,29,30)	FZGGLLMOLZVRHY-UHFFFAOYSA-N	351529	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-2-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 249	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351529&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802866	386053253							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695465	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)C1CCCCN1C	InChI=1S/C25H25Cl2N5O2S/c1-32-8-4-3-5-21(32)25-31-16(13-35-25)12-34-23-11-20-17(10-22(23)33-2)24(29-14-28-20)30-15-6-7-18(26)19(27)9-15/h6-7,9-11,13-14,21H,3-5,8,12H2,1-2H3,(H,28,29,30)	BQCYIIVLNTWNSU-UHFFFAOYSA-N	351530	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2- (1-methylpiperidin-2-yl)-1,3-thiazol-4- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 250	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351530&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802760	386053254							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695470	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)C1CCCNC1	InChI=1S/C24H23Cl2N5O2S/c1-32-21-8-17-20(28-13-29-23(17)30-15-4-5-18(25)19(26)7-15)9-22(21)33-11-16-12-34-24(31-16)14-3-2-6-27-10-14/h4-5,7-9,12-14,27H,2-3,6,10-11H2,1H3,(H,28,29,30)	HFTHZTJJBJKTGD-UHFFFAOYSA-N	351531	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-3-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 251	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802894	386053255							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695475	CCN1CCCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1	InChI=1S/C26H27Cl2N5O2S/c1-3-33-9-5-4-6-22(33)26-32-17(14-36-26)13-35-24-12-21-18(11-23(24)34-2)25(30-15-29-21)31-16-7-8-19(27)20(28)10-16/h7-8,10-12,14-15,22H,3-6,9,13H2,1-2H3,(H,29,30,31)	WVXLPNDNCDLCQW-UHFFFAOYSA-N	351532	N-(3,4-dichlorophenyl)-7-({[2-(1- ethylpiperidin-2-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 253	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351532&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802667	386053256							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695480	CCN1CCCC(C1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1	InChI=1S/C26H27Cl2N5O2S/c1-3-33-8-4-5-16(12-33)26-32-18(14-36-26)13-35-24-11-22-19(10-23(24)34-2)25(30-15-29-22)31-17-6-7-20(27)21(28)9-17/h6-7,9-11,14-16H,3-5,8,12-13H2,1-2H3,(H,29,30,31)	ILENFMLSOQJLGD-UHFFFAOYSA-N	351533	N-(3,4-dichlorophenyl)-7-({[2-(1- ethylpiperidin-3-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 254	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802734	386053257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695485	CCN1CCCC1c1noc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)n1	InChI=1S/C24H24Cl2N6O3/c1-3-32-8-4-5-19(32)24-30-22(35-31-24)12-34-21-11-18-15(10-20(21)33-2)23(28-13-27-18)29-14-6-7-16(25)17(26)9-14/h6-7,9-11,13,19H,3-5,8,12H2,1-2H3,(H,27,28,29)	QYJJHEKFWCNKKZ-UHFFFAOYSA-N	351534	N-(3,4-dichlorophenyl)-7-[({3-[(2S)-1- ethylpyrrolidin-2-yl]-1,2,4-oxadiazol-5- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 255	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351534&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			69667119	386053258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695490	CCN1CCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1	InChI=1S/C25H25Cl2N5O2S/c1-3-32-8-4-5-21(32)25-31-16(13-35-25)12-34-23-11-20-17(10-22(23)33-2)24(29-14-28-20)30-15-6-7-18(26)19(27)9-15/h6-7,9-11,13-14,21H,3-5,8,12H2,1-2H3,(H,28,29,30)	BADQNHXUQWKUBJ-UHFFFAOYSA-N	351535	N-(3,4-dichlorophenyl)-7-[({2-[(2S)-1- ethylpyrrolidin-2-yl]-1,3-thiazol-4- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 256	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			76614846	386053259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695495	CCC1Cc2nc(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)sc2CN1	InChI=1S/C24H23Cl2N5O2S/c1-3-13-7-19-22(10-27-13)34-23(31-19)11-33-21-9-18-15(8-20(21)32-2)24(29-12-28-18)30-14-4-5-16(25)17(26)6-14/h4-6,8-9,12-13,27H,3,7,10-11H2,1-2H3,(H,28,29,30)	UKANZOMXIMJQJI-UHFFFAOYSA-N	351536	N-(3,4-dichlorophenyl)-7-{[(5-ethyl-4,5,6,7- tetrahydro[1,3]thiazolo[5,4-c]pyridin-2- yl)methyl]oxy}-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 257	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351536&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802859	386053260							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695500	CCCN1CCCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1	InChI=1S/C24H28Cl2N4O3/c1-3-7-30-8-4-9-32-17(13-30)14-33-23-12-21-18(11-22(23)31-2)24(28-15-27-21)29-16-5-6-19(25)20(26)10-16/h5-6,10-12,15,17H,3-4,7-9,13-14H2,1-2H3,(H,27,28,29)	TUJUURQEVYFCIN-UHFFFAOYSA-N	351537	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- propyl-1,4-oxazepan-2- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 258	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351537&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802675	386053261							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695505	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CC2CC2)CCCO1	InChI=1S/C25H28Cl2N4O3/c1-32-23-10-19-22(28-15-29-25(19)30-17-5-6-20(26)21(27)9-17)11-24(23)34-14-18-13-31(7-2-8-33-18)12-16-3-4-16/h5-6,9-11,15-16,18H,2-4,7-8,12-14H2,1H3,(H,28,29,30)	XNADADUSWUFNQO-UHFFFAOYSA-N	351538	7-({[4-(cyclopropylmethyl)-1,4-oxazepan-2- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 259	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802751	386053262							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695510	COCCN1CCCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1	InChI=1S/C24H28Cl2N4O4/c1-31-9-7-30-6-3-8-33-17(13-30)14-34-23-12-21-18(11-22(23)32-2)24(28-15-27-21)29-16-4-5-19(25)20(26)10-16/h4-5,10-12,15,17H,3,6-9,13-14H2,1-2H3,(H,27,28,29)	KZIOAIIQBIYJTQ-UHFFFAOYSA-N	351539	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4- [2-(methyloxy)ethyl]-1,4-oxazepan-2- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 260	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802616	386053263							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695515	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCCO1)C(C)C	InChI=1S/C24H28Cl2N4O3/c1-15(2)30-7-4-8-32-17(12-30)13-33-23-11-21-18(10-22(23)31-3)24(28-14-27-21)29-16-5-6-19(25)20(26)9-16/h5-6,9-11,14-15,17H,4,7-8,12-13H2,1-3H3,(H,27,28,29)	PWNBTHIQJMPMTI-UHFFFAOYSA-N	351540	N-(3,4-dichlorophenyl)-7-({[4-(1-methylethyl)- 1,4-oxazepan-2-yl]methyl}oxy)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 261	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802778	386053264							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695520	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)N1CCNCC1	InChI=1S/C23H22Cl2N6O2S/c1-32-20-9-16-19(27-13-28-22(16)29-14-2-3-17(24)18(25)8-14)10-21(20)33-11-15-12-34-23(30-15)31-6-4-26-5-7-31/h2-3,8-10,12-13,26H,4-7,11H2,1H3,(H,27,28,29)	RGUFKCMSOMSTHM-UHFFFAOYSA-N	351541	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperazin-1-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 262	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351541&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802771	386053265							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695525	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCCN1	InChI=1S/C22H20Cl2N6O3/c1-31-18-8-13-17(26-11-27-21(13)28-12-4-5-14(23)15(24)7-12)9-19(18)32-10-20-29-22(33-30-20)16-3-2-6-25-16/h4-5,7-9,11,16,25H,2-3,6,10H2,1H3,(H,26,27,28)	KOSFAPNTMAEMEM-UHFFFAOYSA-N	351542	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- pyrrolidin-2-yl-1,2,4-oxadiazol-3- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 263	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351542&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802670	386053266							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695530	CCN1CCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1	InChI=1S/C24H24Cl2N6O3/c1-3-32-8-4-5-19(32)24-30-22(31-35-24)12-34-21-11-18-15(10-20(21)33-2)23(28-13-27-18)29-14-6-7-16(25)17(26)9-14/h6-7,9-11,13,19H,3-5,8,12H2,1-2H3,(H,27,28,29)	OUPSOAXLJSDWRF-UHFFFAOYSA-N	351543	N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpyrrolidin-2-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 264	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351543&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802597	386053267							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695535	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)[C@@H]1CCCN1C	InChI=1S/C23H22Cl2N6O3/c1-31-7-3-4-18(31)23-29-21(34-30-23)11-33-20-10-17-14(9-19(20)32-2)22(27-12-26-17)28-13-5-6-15(24)16(25)8-13/h5-6,8-10,12,18H,3-4,7,11H2,1-2H3,(H,26,27,28)/t18-/m0/s1	QFHBQKXGJZQISJ-SFHVURJKSA-N	351544	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(2S)-1-methylpyrrolidin-2-yl]-1,2,4-oxadiazol- 5-yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 265	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802624	386053268							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695540	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(n1)[C@@H]1CCCN1C	InChI=1S/C24H23Cl2N5O2S/c1-31-7-3-4-20(31)24-30-15(12-34-24)11-33-22-10-19-16(9-21(22)32-2)23(28-13-27-19)29-14-5-6-17(25)18(26)8-14/h5-6,8-10,12-13,20H,3-4,7,11H2,1-2H3,(H,27,28,29)/t20-/m0/s1	QHTZGTDGFHTCOG-FQEVSTJZSA-N	351545	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [(2S)-1-methylpyrrolidin-2-yl]-1,3-thiazol-4- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 266	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351545&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802581	386053269							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695545	CCN1CCN(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1	InChI=1S/C25H26Cl2N6O2S/c1-3-32-6-8-33(9-7-32)25-31-17(14-36-25)13-35-23-12-21-18(11-22(23)34-2)24(29-15-28-21)30-16-4-5-19(26)20(27)10-16/h4-5,10-12,14-15H,3,6-9,13H2,1-2H3,(H,28,29,30)	PLPFTGVPIXWCIC-UHFFFAOYSA-N	351546	N-(3,4-dichlorophenyl)-7-({[2-(4- ethylpiperazin-1-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 267	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351546&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802655	386053270							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695550	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C)CCN1C	InChI=1S/C22H25Cl2N5O2/c1-28-6-7-29(2)15(11-28)12-31-21-10-19-16(9-20(21)30-3)22(26-13-25-19)27-14-4-5-17(23)18(24)8-14/h4-5,8-10,13,15H,6-7,11-12H2,1-3H3,(H,25,26,27)	JHVXCKPKPWJTHM-UHFFFAOYSA-N	351547	N-(3,4-dichlorophenyl)-7-{[(1,4- dimethylpiperazin-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 268	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351547&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802781	386053271							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695555	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCO1)C1CCCC1	InChI=1S/C25H28Cl2N4O3/c1-32-23-11-19-22(28-15-29-25(19)30-16-6-7-20(26)21(27)10-16)12-24(23)34-14-18-13-31(8-9-33-18)17-4-2-3-5-17/h6-7,10-12,15,17-18H,2-5,8-9,13-14H2,1H3,(H,28,29,30)	JZVGJCJOXIONNM-UHFFFAOYSA-N	351548	7-{[(4-cyclopentylmorpholin-2-yl)methyl]oxy}- N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 269	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351548&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802841	386053272							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695560	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCO1)C(C)C	InChI=1S/C23H26Cl2N4O3/c1-14(2)29-6-7-31-16(11-29)12-32-22-10-20-17(9-21(22)30-3)23(27-13-26-20)28-15-4-5-18(24)19(25)8-15/h4-5,8-10,13-14,16H,6-7,11-12H2,1-3H3,(H,26,27,28)	HYOURUDRVAZLAG-UHFFFAOYSA-N	351549	N-(3,4-dichlorophenyl)-7-({[4-(1- methylethyl)morpholin-2-yl]methyl}oxy)-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 270	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351549&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802594	386053273							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695565	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCCc2ccccc2)CCO1	InChI=1S/C29H30Cl2N4O3/c1-36-27-15-23-26(32-19-33-29(23)34-21-9-10-24(30)25(31)14-21)16-28(27)38-18-22-17-35(12-13-37-22)11-5-8-20-6-3-2-4-7-20/h2-4,6-7,9-10,14-16,19,22H,5,8,11-13,17-18H2,1H3,(H,32,33,34)	QOEMXTGSYTXSBD-UHFFFAOYSA-N	351550	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (3-phenylpropyl)morpholin-2- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 271	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351550&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802758	386053274							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695570	COCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1	InChI=1S/C23H26Cl2N4O4/c1-30-7-5-29-6-8-32-16(12-29)13-33-22-11-20-17(10-21(22)31-2)23(27-14-26-20)28-15-3-4-18(24)19(25)9-15/h3-4,9-11,14,16H,5-8,12-13H2,1-2H3,(H,26,27,28)	ZTUNVYDNGSGYLT-UHFFFAOYSA-N	351551	N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4- [2-(methyloxy)ethyl]morpholin-2- yl}methyl)oxy]quinazolin-4-amine::US9796704, Entry 272	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351551&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802847	386045968							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695575	CCOC(=O)C(C)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1	InChI=1S/C25H28Cl2N4O5/c1-4-34-25(32)15(2)31-7-8-35-17(12-31)13-36-23-11-21-18(10-22(23)33-3)24(29-14-28-21)30-16-5-6-19(26)20(27)9-16/h5-6,9-11,14-15,17H,4,7-8,12-13H2,1-3H3,(H,28,29,30)	BTGGKWOJEKOLEQ-UHFFFAOYSA-N	351552	US9796704, Entry 273::ethyl 2-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7- yl]oxy}methyl)morpholin-4-yl]propanoate	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351552&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802635	386045969							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695580	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCCCC=C)CCO1	InChI=1S/C26H30Cl2N4O3/c1-3-4-5-6-9-32-10-11-34-19(15-32)16-35-25-14-23-20(13-24(25)33-2)26(30-17-29-23)31-18-7-8-21(27)22(28)12-18/h3,7-8,12-14,17,19H,1,4-6,9-11,15-16H2,2H3,(H,29,30,31)	ZQCZQQPQOHFPCA-UHFFFAOYSA-N	351553	N-(3,4-dichlorophenyl)-7-{[(4-hex-5-en-1- ylmorpholin-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 274	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351553&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802850	386045970							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695585	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCOCCO)CCO1	InChI=1S/C24H28Cl2N4O5/c1-32-22-11-18-21(27-15-28-24(18)29-16-2-3-19(25)20(26)10-16)12-23(22)35-14-17-13-30(5-8-34-17)4-7-33-9-6-31/h2-3,10-12,15,17,31H,4-9,13-14H2,1H3,(H,27,28,29)	VDNKDMALAXYLFZ-UHFFFAOYSA-N	351554	2-({2-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7- yl]oxy}methyl)morpholin-4- yl]ethyl}oxy)ethanol::US9796704, Entry 275	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351554&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802703	386045971							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695590	COC(=O)CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1	InChI=1S/C24H26Cl2N4O5/c1-32-21-10-17-20(27-14-28-24(17)29-15-3-4-18(25)19(26)9-15)11-22(21)35-13-16-12-30(7-8-34-16)6-5-23(31)33-2/h3-4,9-11,14,16H,5-8,12-13H2,1-2H3,(H,27,28,29)	ZEIOSBCSTUSZSU-UHFFFAOYSA-N	351555	US9796704, Entry 276::methyl 3-[2-({[4-[(3,4-dichlorophenyl)amino]- 6-(methyloxy)quinazolin-7- yl]oxy}methyl)morpholin-4-yl]propanoate	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351555&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802790	386045972							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
695595	COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCCCCC#N)CCO1	InChI=1S/C26H29Cl2N5O3/c1-34-24-13-20-23(30-17-31-26(20)32-18-6-7-21(27)22(28)12-18)14-25(24)36-16-19-15-33(10-11-35-19)9-5-3-2-4-8-29/h6-7,12-14,17,19H,2-5,9-11,15-16H2,1H3,(H,30,31,32)	AVADFQHEIADTFF-UHFFFAOYSA-N	351556	6-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7- yl]oxy}methyl)morpholin-4-yl]hexanenitrile::US9796704, Entry 277	Epidermal growth factor receptor	Homo sapiens		<50							US Patent		10.7270/Q28K7C6V		aid1797499	US9796704	Rice, KD; Anand, NK; Bussenius, J; Costanzo, S; Kennedy, AR; Peto, CJ; Tsang, TH; Blazey, CM	10/24/2017	9/23/2019	SYMPHONY EVOLUTION, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=351556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=351556&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57802611	386045973							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	1IVO,1M14,1M17,1MOX,1XKK,1Z9I,2GS2,2GS6,2ITW,2ITX,2ITY,2J5E,2J5F,2J6M,2N5S,2RF9,2RGP,3B2V,3BEL,3GOP,3POZ,3QWQ,3VJO,3W2O,3W2P,3W2Q,3W2R,3W2S,3W32,3W33,4G5J,4I23,4JQ7,4JQ8,4JR3,4JRV,4KRO,4LI5,4RJ4,4RJ5,4RJ6,4RJ7,4RJ8,4TKS,4UIP,4UV7,4WKQ,4WRG,4ZAU,5C8K,5C8M,5C8N,5CAL,5CAN,5CAO,5CAP,5CAQ,5CAS,5CAU,5CAV,5EDP,5EDQ,5EDR,5EM5,5EM6,5EM7,5EM8,5FED,5GNK,5HCX,5HCY,5HCZ,5HIB,5HIC,5UGB,5WB7,5WB8,5Y25,6D8E,6JZ0,6S89,6S8A,6VH4,6VHN,6VHP,7AEI,7AEM,7B85,7OXB,7SI1,7T4I,7UKV,7ZYM,7ZYN,7ZYP,8A27,8A2A,8HY7	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727903	CCc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cnn2ccccc12	InChI=1S/C28H34N8O2/c1-7-19-17-29-28(33-27(19)20-18-30-36-12-10-9-11-23(20)36)32-22-15-21(31-26(37)8-2)24(16-25(22)38-6)35(5)14-13-34(3)4/h8-12,15-18H,2,7,13-14H2,1,3-6H3,(H,31,37)(H,29,32,33)	LBIOKJBIXFMNFN-UHFFFAOYSA-N	368365	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((5-ethyl-4-(pyrazolo[1,5-a]pyridin-3-yl)pyrimidin-2-yl)amino)-4-methoxyphenyl)acrylamide::US10227342, Example 1	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368365	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368365&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618506	402365206							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727905	CCc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cnn2ccccc12	InChI=1S/C28H34N8O2/c1-7-19-17-29-28(33-27(19)20-18-30-36-12-10-9-11-23(20)36)32-22-15-21(31-26(37)8-2)24(16-25(22)38-6)35(5)14-13-34(3)4/h8-12,15-18H,2,7,13-14H2,1,3-6H3,(H,31,37)(H,29,32,33)	LBIOKJBIXFMNFN-UHFFFAOYSA-N	368365	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((5-ethyl-4-(pyrazolo[1,5-a]pyridin-3-yl)pyrimidin-2-yl)amino)-4-methoxyphenyl)acrylamide::US10227342, Example 1	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368365	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368365&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618506	402365206							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727906	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(C2=CCOCC2)n(C)c2ccccc12 |t:31|	InChI=1S/C32H38N8O3/c1-7-28(41)35-23-18-24(27(42-6)19-26(23)39(4)15-14-38(2)3)36-32-34-20-33-31(37-32)29-22-10-8-9-11-25(22)40(5)30(29)21-12-16-43-17-13-21/h7-12,18-20H,1,13-17H2,2-6H3,(H,35,41)(H,33,34,36,37)	WFEZUFSKPBOQPJ-UHFFFAOYSA-N	368366	US10227342, Example 2	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368366&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607863	402365207							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727907	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(C2=CCOCC2)n(C)c2ccccc12 |t:31|	InChI=1S/C32H38N8O3/c1-7-28(41)35-23-18-24(27(42-6)19-26(23)39(4)15-14-38(2)3)36-32-34-20-33-31(37-32)29-22-10-8-9-11-25(22)40(5)30(29)21-12-16-43-17-13-21/h7-12,18-20H,1,13-17H2,2-6H3,(H,35,41)(H,33,34,36,37)	WFEZUFSKPBOQPJ-UHFFFAOYSA-N	368366	US10227342, Example 2	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368366&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607863	402365207							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727909	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(C2=CCOCC2)n(C)c2ccccc12 |t:31|	InChI=1S/C32H38N8O3/c1-7-28(41)35-23-18-24(27(42-6)19-26(23)39(4)15-14-38(2)3)36-32-34-20-33-31(37-32)29-22-10-8-9-11-25(22)40(5)30(29)21-12-16-43-17-13-21/h7-12,18-20H,1,13-17H2,2-6H3,(H,35,41)(H,33,34,36,37)	WFEZUFSKPBOQPJ-UHFFFAOYSA-N	368366	US10227342, Example 2	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368366&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607863	402365207							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727910	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(-c2ccccc2)n(C)c2ccccc12	InChI=1S/C33H36N8O2/c1-7-29(42)36-24-19-25(28(43-6)20-27(24)40(4)18-17-39(2)3)37-33-35-21-34-32(38-33)30-23-15-11-12-16-26(23)41(5)31(30)22-13-9-8-10-14-22/h7-16,19-21H,1,17-18H2,2-6H3,(H,36,42)(H,34,35,37,38)	IWAUXOPIQTWFGS-UHFFFAOYSA-N	368367	US10227342, Example 3	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368367&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607784	402365208							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727911	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(-c2ccccc2)n(C)c2ccccc12	InChI=1S/C33H36N8O2/c1-7-29(42)36-24-19-25(28(43-6)20-27(24)40(4)18-17-39(2)3)37-33-35-21-34-32(38-33)30-23-15-11-12-16-26(23)41(5)31(30)22-13-9-8-10-14-22/h7-16,19-21H,1,17-18H2,2-6H3,(H,36,42)(H,34,35,37,38)	IWAUXOPIQTWFGS-UHFFFAOYSA-N	368367	US10227342, Example 3	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368367&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607784	402365208							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727913	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(-c2ccccc2)n(C)c2ccccc12	InChI=1S/C33H36N8O2/c1-7-29(42)36-24-19-25(28(43-6)20-27(24)40(4)18-17-39(2)3)37-33-35-21-34-32(38-33)30-23-15-11-12-16-26(23)41(5)31(30)22-13-9-8-10-14-22/h7-16,19-21H,1,17-18H2,2-6H3,(H,36,42)(H,34,35,37,38)	IWAUXOPIQTWFGS-UHFFFAOYSA-N	368367	US10227342, Example 3	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368367&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607784	402365208							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727914	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(C2CCOCC2)n(C)c2ccccc12	InChI=1S/C32H40N8O3/c1-7-28(41)35-23-18-24(27(42-6)19-26(23)39(4)15-14-38(2)3)36-32-34-20-33-31(37-32)29-22-10-8-9-11-25(22)40(5)30(29)21-12-16-43-17-13-21/h7-11,18-21H,1,12-17H2,2-6H3,(H,35,41)(H,33,34,36,37)	MUZAUZJAQNJISB-UHFFFAOYSA-N	368368	US10227342, Example 4	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368368&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607802	402365209							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727915	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(C2CCOCC2)n(C)c2ccccc12	InChI=1S/C32H40N8O3/c1-7-28(41)35-23-18-24(27(42-6)19-26(23)39(4)15-14-38(2)3)36-32-34-20-33-31(37-32)29-22-10-8-9-11-25(22)40(5)30(29)21-12-16-43-17-13-21/h7-11,18-21H,1,12-17H2,2-6H3,(H,35,41)(H,33,34,36,37)	MUZAUZJAQNJISB-UHFFFAOYSA-N	368368	US10227342, Example 4	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368368&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607802	402365209							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727917	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncnc(n1)-c1c(C2CCOCC2)n(C)c2ccccc12	InChI=1S/C32H40N8O3/c1-7-28(41)35-23-18-24(27(42-6)19-26(23)39(4)15-14-38(2)3)36-32-34-20-33-31(37-32)29-22-10-8-9-11-25(22)40(5)30(29)21-12-16-43-17-13-21/h7-11,18-21H,1,12-17H2,2-6H3,(H,35,41)(H,33,34,36,37)	MUZAUZJAQNJISB-UHFFFAOYSA-N	368368	US10227342, Example 4	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368368&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607802	402365209							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727918	COOc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2ccc(OCc3ccccn3)c(Cl)c2)n(C)c2ccccc12	InChI=1S/C40H41ClN8O4/c1-7-37(50)44-31-23-32(36(53-51-6)24-34(31)48(4)21-20-47(2)3)46-40-43-19-17-30(45-40)38-28-13-8-9-14-33(28)49(5)39(38)26-15-16-35(29(41)22-26)52-25-27-12-10-11-18-42-27/h7-19,22-24H,1,20-21,25H2,2-6H3,(H,44,50)(H,43,45,46)	VGQWMEZKPBNXQG-UHFFFAOYSA-N	368369	US10227342, Example 5	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130218134	402365210							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727919	COOc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2ccc(OCc3ccccn3)c(Cl)c2)n(C)c2ccccc12	InChI=1S/C40H41ClN8O4/c1-7-37(50)44-31-23-32(36(53-51-6)24-34(31)48(4)21-20-47(2)3)46-40-43-19-17-30(45-40)38-28-13-8-9-14-33(28)49(5)39(38)26-15-16-35(29(41)22-26)52-25-27-12-10-11-18-42-27/h7-19,22-24H,1,20-21,25H2,2-6H3,(H,44,50)(H,43,45,46)	VGQWMEZKPBNXQG-UHFFFAOYSA-N	368369	US10227342, Example 5	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130218134	402365210							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727922	COOc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2ccc(OCc3ccccn3)c(Cl)c2)n(C)c2ccccc12	InChI=1S/C40H41ClN8O4/c1-7-37(50)44-31-23-32(36(53-51-6)24-34(31)48(4)21-20-47(2)3)46-40-43-19-17-30(45-40)38-28-13-8-9-14-33(28)49(5)39(38)26-15-16-35(29(41)22-26)52-25-27-12-10-11-18-42-27/h7-19,22-24H,1,20-21,25H2,2-6H3,(H,44,50)(H,43,45,46)	VGQWMEZKPBNXQG-UHFFFAOYSA-N	368369	US10227342, Example 5	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130218134	402365210							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727923	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2cncc(Cl)c2)n(C)c2ccccc12	InChI=1S/C33H35ClN8O2/c1-7-30(43)37-25-17-26(29(44-6)18-28(25)41(4)15-14-40(2)3)39-33-36-13-12-24(38-33)31-23-10-8-9-11-27(23)42(5)32(31)21-16-22(34)20-35-19-21/h7-13,16-20H,1,14-15H2,2-6H3,(H,37,43)(H,36,38,39)	KWLYMVLAQZSJPM-UHFFFAOYSA-N	368370	US10227342, Example 6	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618218	402365211							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727924	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2cncc(Cl)c2)n(C)c2ccccc12	InChI=1S/C33H35ClN8O2/c1-7-30(43)37-25-17-26(29(44-6)18-28(25)41(4)15-14-40(2)3)39-33-36-13-12-24(38-33)31-23-10-8-9-11-27(23)42(5)32(31)21-16-22(34)20-35-19-21/h7-13,16-20H,1,14-15H2,2-6H3,(H,37,43)(H,36,38,39)	KWLYMVLAQZSJPM-UHFFFAOYSA-N	368370	US10227342, Example 6	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618218	402365211							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727926	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2cncc(Cl)c2)n(C)c2ccccc12	InChI=1S/C33H35ClN8O2/c1-7-30(43)37-25-17-26(29(44-6)18-28(25)41(4)15-14-40(2)3)39-33-36-13-12-24(38-33)31-23-10-8-9-11-27(23)42(5)32(31)21-16-22(34)20-35-19-21/h7-13,16-20H,1,14-15H2,2-6H3,(H,37,43)(H,36,38,39)	KWLYMVLAQZSJPM-UHFFFAOYSA-N	368370	US10227342, Example 6	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618218	402365211							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727927	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2ccccc2)n(C)c2ccccc12	InChI=1S/C34H37N7O2/c1-7-31(42)36-26-21-27(30(43-6)22-29(26)40(4)20-19-39(2)3)38-34-35-18-17-25(37-34)32-24-15-11-12-16-28(24)41(5)33(32)23-13-9-8-10-14-23/h7-18,21-22H,1,19-20H2,2-6H3,(H,36,42)(H,35,37,38)	POQQAMHSLBUZFZ-UHFFFAOYSA-N	368371	US10227342, Example 7	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618174	402365212							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727928	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2ccccc2)n(C)c2ccccc12	InChI=1S/C34H37N7O2/c1-7-31(42)36-26-21-27(30(43-6)22-29(26)40(4)20-19-39(2)3)38-34-35-18-17-25(37-34)32-24-15-11-12-16-28(24)41(5)33(32)23-13-9-8-10-14-23/h7-18,21-22H,1,19-20H2,2-6H3,(H,36,42)(H,35,37,38)	POQQAMHSLBUZFZ-UHFFFAOYSA-N	368371	US10227342, Example 7	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618174	402365212							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727931	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(-c2ccccc2)n(C)c2ccccc12	InChI=1S/C34H37N7O2/c1-7-31(42)36-26-21-27(30(43-6)22-29(26)40(4)20-19-39(2)3)38-34-35-18-17-25(37-34)32-24-15-11-12-16-28(24)41(5)33(32)23-13-9-8-10-14-23/h7-18,21-22H,1,19-20H2,2-6H3,(H,36,42)(H,35,37,38)	POQQAMHSLBUZFZ-UHFFFAOYSA-N	368371	US10227342, Example 7	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618174	402365212							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727932	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H35N7O4/c1-8-27(38)32-22-15-23(26(40-6)16-25(22)36(4)14-13-35(2)3)33-30-31-17-20(29(39)41-7)28(34-30)21-18-37(5)24-12-10-9-11-19(21)24/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	RXAZQWJCOUIOPS-UHFFFAOYSA-N	368372	US10227342, Example 8	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607783	402365213							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727933	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H35N7O4/c1-8-27(38)32-22-15-23(26(40-6)16-25(22)36(4)14-13-35(2)3)33-30-31-17-20(29(39)41-7)28(34-30)21-18-37(5)24-12-10-9-11-19(21)24/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	RXAZQWJCOUIOPS-UHFFFAOYSA-N	368372	US10227342, Example 8	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607783	402365213							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727935	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H35N7O4/c1-8-27(38)32-22-15-23(26(40-6)16-25(22)36(4)14-13-35(2)3)33-30-31-17-20(29(39)41-7)28(34-30)21-18-37(5)24-12-10-9-11-19(21)24/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	RXAZQWJCOUIOPS-UHFFFAOYSA-N	368372	US10227342, Example 8	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607783	402365213							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727936	CCOC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)33-23-16-24(27(41-7)17-26(23)37(5)15-14-36(3)4)34-31-32-18-21(30(40)42-9-2)29(35-31)22-19-38(6)25-13-11-10-12-20(22)25/h8,10-13,16-19H,1,9,14-15H2,2-7H3,(H,33,39)(H,32,34,35)	FCZMHSXKERLEIN-UHFFFAOYSA-N	368373	US10227342, Example 9	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618504	402365214							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727937	CCOC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)33-23-16-24(27(41-7)17-26(23)37(5)15-14-36(3)4)34-31-32-18-21(30(40)42-9-2)29(35-31)22-19-38(6)25-13-11-10-12-20(22)25/h8,10-13,16-19H,1,9,14-15H2,2-7H3,(H,33,39)(H,32,34,35)	FCZMHSXKERLEIN-UHFFFAOYSA-N	368373	US10227342, Example 9	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618504	402365214							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727940	CCOC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)33-23-16-24(27(41-7)17-26(23)37(5)15-14-36(3)4)34-31-32-18-21(30(40)42-9-2)29(35-31)22-19-38(6)25-13-11-10-12-20(22)25/h8,10-13,16-19H,1,9,14-15H2,2-7H3,(H,33,39)(H,32,34,35)	FCZMHSXKERLEIN-UHFFFAOYSA-N	368373	US10227342, Example 9	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618504	402365214							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727941	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(6)15-14-37(4)5)35-32-33-18-22(31(41)43-20(2)3)30(36-32)23-19-39(7)26-13-11-10-12-21(23)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	AZSRSNUQCUDCGG-UHFFFAOYSA-N	368374	US10227342, Example 10	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607832	402365215							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727942	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(6)15-14-37(4)5)35-32-33-18-22(31(41)43-20(2)3)30(36-32)23-19-39(7)26-13-11-10-12-21(23)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	AZSRSNUQCUDCGG-UHFFFAOYSA-N	368374	US10227342, Example 10	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607832	402365215							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727945	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(6)15-14-37(4)5)35-32-33-18-22(31(41)43-20(2)3)30(36-32)23-19-39(7)26-13-11-10-12-21(23)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	AZSRSNUQCUDCGG-UHFFFAOYSA-N	368374	US10227342, Example 10	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607832	402365215							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727946	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2COC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H37N7O5/c1-7-29(40)34-24-14-25(28(42-6)15-27(24)38(4)13-12-37(2)3)35-32-33-16-22(31(41)44-20-18-43-19-20)30(36-32)23-17-39(5)26-11-9-8-10-21(23)26/h7-11,14-17,20H,1,12-13,18-19H2,2-6H3,(H,34,40)(H,33,35,36)	LJRBKOAVHPUJIM-UHFFFAOYSA-N	368375	US10227342, Example 11	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607842	402365216							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727947	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2COC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H37N7O5/c1-7-29(40)34-24-14-25(28(42-6)15-27(24)38(4)13-12-37(2)3)35-32-33-16-22(31(41)44-20-18-43-19-20)30(36-32)23-17-39(5)26-11-9-8-10-21(23)26/h7-11,14-17,20H,1,12-13,18-19H2,2-6H3,(H,34,40)(H,33,35,36)	LJRBKOAVHPUJIM-UHFFFAOYSA-N	368375	US10227342, Example 11	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607842	402365216							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727949	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2COC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H37N7O5/c1-7-29(40)34-24-14-25(28(42-6)15-27(24)38(4)13-12-37(2)3)35-32-33-16-22(31(41)44-20-18-43-19-20)30(36-32)23-17-39(5)26-11-9-8-10-21(23)26/h7-11,14-17,20H,1,12-13,18-19H2,2-6H3,(H,34,40)(H,33,35,36)	LJRBKOAVHPUJIM-UHFFFAOYSA-N	368375	US10227342, Example 11	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607842	402365216							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727950	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2CN(C)C2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H40N8O4/c1-8-30(42)35-25-15-26(29(44-7)16-28(25)40(5)14-13-38(2)3)36-33-34-17-23(32(43)45-21-18-39(4)19-21)31(37-33)24-20-41(6)27-12-10-9-11-22(24)27/h8-12,15-17,20-21H,1,13-14,18-19H2,2-7H3,(H,35,42)(H,34,36,37)	ITLAIDVEUVKTAK-UHFFFAOYSA-N	368376	US10227342, Example 12	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618159	402365217							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727951	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2CN(C)C2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H40N8O4/c1-8-30(42)35-25-15-26(29(44-7)16-28(25)40(5)14-13-38(2)3)36-33-34-17-23(32(43)45-21-18-39(4)19-21)31(37-33)24-20-41(6)27-12-10-9-11-22(24)27/h8-12,15-17,20-21H,1,13-14,18-19H2,2-7H3,(H,35,42)(H,34,36,37)	ITLAIDVEUVKTAK-UHFFFAOYSA-N	368376	US10227342, Example 12	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618159	402365217							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727953	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2CN(C)C2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H40N8O4/c1-8-30(42)35-25-15-26(29(44-7)16-28(25)40(5)14-13-38(2)3)36-33-34-17-23(32(43)45-21-18-39(4)19-21)31(37-33)24-20-41(6)27-12-10-9-11-22(24)27/h8-12,15-17,20-21H,1,13-14,18-19H2,2-7H3,(H,35,42)(H,34,36,37)	ITLAIDVEUVKTAK-UHFFFAOYSA-N	368376	US10227342, Example 12	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618159	402365217							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727954	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC2CC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)15-14-38(2)3)36-33-34-18-23(32(42)44-20-21-12-13-21)31(37-33)24-19-40(5)27-11-9-8-10-22(24)27/h7-11,16-19,21H,1,12-15,20H2,2-6H3,(H,35,41)(H,34,36,37)	PFWGSFHALNIOLP-UHFFFAOYSA-N	368377	US10227342, Example 13	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607771	402365218							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727955	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC2CC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)15-14-38(2)3)36-33-34-18-23(32(42)44-20-21-12-13-21)31(37-33)24-19-40(5)27-11-9-8-10-22(24)27/h7-11,16-19,21H,1,12-15,20H2,2-6H3,(H,35,41)(H,34,36,37)	PFWGSFHALNIOLP-UHFFFAOYSA-N	368377	US10227342, Example 13	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607771	402365218							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727957	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC2CC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)15-14-38(2)3)36-33-34-18-23(32(42)44-20-21-12-13-21)31(37-33)24-19-40(5)27-11-9-8-10-22(24)27/h7-11,16-19,21H,1,12-15,20H2,2-6H3,(H,35,41)(H,34,36,37)	PFWGSFHALNIOLP-UHFFFAOYSA-N	368377	US10227342, Example 13	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607771	402365218							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727958	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2CCC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-17-26(29(43-6)18-28(25)39(4)16-15-38(2)3)36-33-34-19-23(32(42)44-21-11-10-12-21)31(37-33)24-20-40(5)27-14-9-8-13-22(24)27/h7-9,13-14,17-21H,1,10-12,15-16H2,2-6H3,(H,35,41)(H,34,36,37)	LDZREOHPCZNERK-UHFFFAOYSA-N	368379	US10227342, Example 14	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607831	402365220							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727959	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2CCC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-17-26(29(43-6)18-28(25)39(4)16-15-38(2)3)36-33-34-19-23(32(42)44-21-11-10-12-21)31(37-33)24-20-40(5)27-14-9-8-13-22(24)27/h7-9,13-14,17-21H,1,10-12,15-16H2,2-6H3,(H,35,41)(H,34,36,37)	LDZREOHPCZNERK-UHFFFAOYSA-N	368379	US10227342, Example 14	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607831	402365220							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727961	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC2CCC2)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-17-26(29(43-6)18-28(25)39(4)16-15-38(2)3)36-33-34-19-23(32(42)44-21-11-10-12-21)31(37-33)24-20-40(5)27-14-9-8-13-22(24)27/h7-9,13-14,17-21H,1,10-12,15-16H2,2-6H3,(H,35,41)(H,34,36,37)	LDZREOHPCZNERK-UHFFFAOYSA-N	368379	US10227342, Example 14	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607831	402365220							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727962	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1ccc2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)33-23-17-24(27(41-7)18-26(23)37(6)16-15-36(4)5)34-31-32-19-22(30(40)42-20(2)3)29(35-31)38-14-13-21-11-9-10-12-25(21)38/h8-14,17-20H,1,15-16H2,2-7H3,(H,33,39)(H,32,34,35)	JRCQXICTSPIIKB-UHFFFAOYSA-N	368380	US10227342, Example 15	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607807	402365221							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727963	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1ccc2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)33-23-17-24(27(41-7)18-26(23)37(6)16-15-36(4)5)34-31-32-19-22(30(40)42-20(2)3)29(35-31)38-14-13-21-11-9-10-12-25(21)38/h8-14,17-20H,1,15-16H2,2-7H3,(H,33,39)(H,32,34,35)	JRCQXICTSPIIKB-UHFFFAOYSA-N	368380	US10227342, Example 15	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607807	402365221							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727965	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1ccc2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)33-23-17-24(27(41-7)18-26(23)37(6)16-15-36(4)5)34-31-32-19-22(30(40)42-20(2)3)29(35-31)38-14-13-21-11-9-10-12-25(21)38/h8-14,17-20H,1,15-16H2,2-7H3,(H,33,39)(H,32,34,35)	JRCQXICTSPIIKB-UHFFFAOYSA-N	368380	US10227342, Example 15	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607807	402365221							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727966	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CC2CCCN2C)nc1-c1cn(C)c2ccccc12	InChI=1S/C32H37N7O4/c1-7-29(40)34-24-15-25(28(42-5)16-27(24)38(3)18-20-11-10-14-37(20)2)35-32-33-17-22(31(41)43-6)30(36-32)23-19-39(4)26-13-9-8-12-21(23)26/h7-9,12-13,15-17,19-20H,1,10-11,14,18H2,2-6H3,(H,34,40)(H,33,35,36)	GOWRIIAEBKTUPA-UHFFFAOYSA-N	368381	US10227342, Example 16	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607766	402365222							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727967	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CC2CCCN2C)nc1-c1cn(C)c2ccccc12	InChI=1S/C32H37N7O4/c1-7-29(40)34-24-15-25(28(42-5)16-27(24)38(3)18-20-11-10-14-37(20)2)35-32-33-17-22(31(41)43-6)30(36-32)23-19-39(4)26-13-9-8-12-21(23)26/h7-9,12-13,15-17,19-20H,1,10-11,14,18H2,2-6H3,(H,34,40)(H,33,35,36)	GOWRIIAEBKTUPA-UHFFFAOYSA-N	368381	US10227342, Example 16	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607766	402365222							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727969	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CC2CCCN2C)nc1-c1cn(C)c2ccccc12	InChI=1S/C32H37N7O4/c1-7-29(40)34-24-15-25(28(42-5)16-27(24)38(3)18-20-11-10-14-37(20)2)35-32-33-17-22(31(41)43-6)30(36-32)23-19-39(4)26-13-9-8-12-21(23)26/h7-9,12-13,15-17,19-20H,1,10-11,14,18H2,2-6H3,(H,34,40)(H,33,35,36)	GOWRIIAEBKTUPA-UHFFFAOYSA-N	368381	US10227342, Example 16	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607766	402365222							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727970	COc1cc(N(C)CC2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368382	US10227342, Example 17	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368382&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607809	402365223							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727971	COc1cc(N(C)CC2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368382	US10227342, Example 17	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368382&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607809	402365223							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727974	COc1cc(N(C)CC2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368382	US10227342, Example 17	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368382&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607809	402365223							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727975	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2cc(OCCN3CCN(C)CC3)ccc12	InChI=1S/C30H34ClN7O3/c1-5-28(39)33-20-6-9-27(40-4)25(16-20)34-30-32-18-24(31)29(35-30)23-19-37(3)26-17-21(7-8-22(23)26)41-15-14-38-12-10-36(2)11-13-38/h5-9,16-19H,1,10-15H2,2-4H3,(H,33,39)(H,32,34,35)	OHLRYNKVESZBFJ-UHFFFAOYSA-N	368383	US10227342, Example 18	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607805	402365224							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727976	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2cc(OCCN3CCN(C)CC3)ccc12	InChI=1S/C30H34ClN7O3/c1-5-28(39)33-20-6-9-27(40-4)25(16-20)34-30-32-18-24(31)29(35-30)23-19-37(3)26-17-21(7-8-22(23)26)41-15-14-38-12-10-36(2)11-13-38/h5-9,16-19H,1,10-15H2,2-4H3,(H,33,39)(H,32,34,35)	OHLRYNKVESZBFJ-UHFFFAOYSA-N	368383	US10227342, Example 18	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607805	402365224							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727978	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2cc(OCCN3CCN(C)CC3)ccc12	InChI=1S/C30H34ClN7O3/c1-5-28(39)33-20-6-9-27(40-4)25(16-20)34-30-32-18-24(31)29(35-30)23-19-37(3)26-17-21(7-8-22(23)26)41-15-14-38-12-10-36(2)11-13-38/h5-9,16-19H,1,10-15H2,2-4H3,(H,33,39)(H,32,34,35)	OHLRYNKVESZBFJ-UHFFFAOYSA-N	368383	US10227342, Example 18	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607805	402365224							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727979	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCCN(C)C)ccc12	InChI=1S/C29H31N7O3/c1-6-27(37)32-20-8-11-26(38-5)24(14-20)33-29-31-17-19(16-30)28(34-29)23-18-36(4)25-15-21(9-10-22(23)25)39-13-7-12-35(2)3/h6,8-11,14-15,17-18H,1,7,12-13H2,2-5H3,(H,32,37)(H,31,33,34)	WLIPFWISCXKNAC-UHFFFAOYSA-N	368384	US10227342, Example 19	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607833	402365225							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727980	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCCN(C)C)ccc12	InChI=1S/C29H31N7O3/c1-6-27(37)32-20-8-11-26(38-5)24(14-20)33-29-31-17-19(16-30)28(34-29)23-18-36(4)25-15-21(9-10-22(23)25)39-13-7-12-35(2)3/h6,8-11,14-15,17-18H,1,7,12-13H2,2-5H3,(H,32,37)(H,31,33,34)	WLIPFWISCXKNAC-UHFFFAOYSA-N	368384	US10227342, Example 19	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607833	402365225							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727982	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCCN(C)C)ccc12	InChI=1S/C29H31N7O3/c1-6-27(37)32-20-8-11-26(38-5)24(14-20)33-29-31-17-19(16-30)28(34-29)23-18-36(4)25-15-21(9-10-22(23)25)39-13-7-12-35(2)3/h6,8-11,14-15,17-18H,1,7,12-13H2,2-5H3,(H,32,37)(H,31,33,34)	WLIPFWISCXKNAC-UHFFFAOYSA-N	368384	US10227342, Example 19	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607833	402365225							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727983	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCN3CCCC3)ccc12	InChI=1S/C30H31N7O3/c1-4-28(38)33-21-7-10-27(39-3)25(15-21)34-30-32-18-20(17-31)29(35-30)24-19-36(2)26-16-22(8-9-23(24)26)40-14-13-37-11-5-6-12-37/h4,7-10,15-16,18-19H,1,5-6,11-14H2,2-3H3,(H,33,38)(H,32,34,35)	UGIZXCXBUCWMTJ-UHFFFAOYSA-N	368385	US10227342, Example 20	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368385&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607824	402365226							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727984	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCN3CCCC3)ccc12	InChI=1S/C30H31N7O3/c1-4-28(38)33-21-7-10-27(39-3)25(15-21)34-30-32-18-20(17-31)29(35-30)24-19-36(2)26-16-22(8-9-23(24)26)40-14-13-37-11-5-6-12-37/h4,7-10,15-16,18-19H,1,5-6,11-14H2,2-3H3,(H,33,38)(H,32,34,35)	UGIZXCXBUCWMTJ-UHFFFAOYSA-N	368385	US10227342, Example 20	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368385&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607824	402365226							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727986	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCN3CCCC3)ccc12	InChI=1S/C30H31N7O3/c1-4-28(38)33-21-7-10-27(39-3)25(15-21)34-30-32-18-20(17-31)29(35-30)24-19-36(2)26-16-22(8-9-23(24)26)40-14-13-37-11-5-6-12-37/h4,7-10,15-16,18-19H,1,5-6,11-14H2,2-3H3,(H,33,38)(H,32,34,35)	UGIZXCXBUCWMTJ-UHFFFAOYSA-N	368385	US10227342, Example 20	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368385&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607824	402365226							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727987	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCC3CCCN3C)ccc12	InChI=1S/C30H31N7O3/c1-5-28(38)33-20-8-11-27(39-4)25(13-20)34-30-32-16-19(15-31)29(35-30)24-17-37(3)26-14-22(9-10-23(24)26)40-18-21-7-6-12-36(21)2/h5,8-11,13-14,16-17,21H,1,6-7,12,18H2,2-4H3,(H,33,38)(H,32,34,35)	WTGOEKBHPRCTCB-UHFFFAOYSA-N	368386	US10227342, Example 21	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607769	402365227							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727988	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCC3CCCN3C)ccc12	InChI=1S/C30H31N7O3/c1-5-28(38)33-20-8-11-27(39-4)25(13-20)34-30-32-16-19(15-31)29(35-30)24-17-37(3)26-14-22(9-10-23(24)26)40-18-21-7-6-12-36(21)2/h5,8-11,13-14,16-17,21H,1,6-7,12,18H2,2-4H3,(H,33,38)(H,32,34,35)	WTGOEKBHPRCTCB-UHFFFAOYSA-N	368386	US10227342, Example 21	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607769	402365227							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727990	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCC3CCCN3C)ccc12	InChI=1S/C30H31N7O3/c1-5-28(38)33-20-8-11-27(39-4)25(13-20)34-30-32-16-19(15-31)29(35-30)24-17-37(3)26-14-22(9-10-23(24)26)40-18-21-7-6-12-36(21)2/h5,8-11,13-14,16-17,21H,1,6-7,12,18H2,2-4H3,(H,33,38)(H,32,34,35)	WTGOEKBHPRCTCB-UHFFFAOYSA-N	368386	US10227342, Example 21	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607769	402365227							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727991	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2cc(OCCN3CCCC3)ccc12	InChI=1S/C28H29ClN6O3/c1-3-26(36)32-18-6-9-25(37-2)24(14-18)33-28-31-17-22(29)27(34-28)21-16-30-23-15-19(7-8-20(21)23)38-13-12-35-10-4-5-11-35/h3,6-9,14-17,30H,1,4-5,10-13H2,2H3,(H,32,36)(H,31,33,34)	PKVNZDQZOMZPIS-UHFFFAOYSA-N	368387	US10227342, Example 22	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607872	402365228							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727992	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2cc(OCCN3CCCC3)ccc12	InChI=1S/C28H29ClN6O3/c1-3-26(36)32-18-6-9-25(37-2)24(14-18)33-28-31-17-22(29)27(34-28)21-16-30-23-15-19(7-8-20(21)23)38-13-12-35-10-4-5-11-35/h3,6-9,14-17,30H,1,4-5,10-13H2,2H3,(H,32,36)(H,31,33,34)	PKVNZDQZOMZPIS-UHFFFAOYSA-N	368387	US10227342, Example 22	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607872	402365228							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727994	COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2cc(OCCN3CCCC3)ccc12	InChI=1S/C28H29ClN6O3/c1-3-26(36)32-18-6-9-25(37-2)24(14-18)33-28-31-17-22(29)27(34-28)21-16-30-23-15-19(7-8-20(21)23)38-13-12-35-10-4-5-11-35/h3,6-9,14-17,30H,1,4-5,10-13H2,2H3,(H,32,36)(H,31,33,34)	PKVNZDQZOMZPIS-UHFFFAOYSA-N	368387	US10227342, Example 22	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607872	402365228							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727995	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCC3CCCN3C)ccc12	InChI=1S/C31H33N7O3/c1-5-29(39)34-21-8-11-28(40-4)26(15-21)35-31-33-18-20(17-32)30(36-31)25-19-38(3)27-16-23(9-10-24(25)27)41-14-12-22-7-6-13-37(22)2/h5,8-11,15-16,18-19,22H,1,6-7,12-14H2,2-4H3,(H,34,39)(H,33,35,36)	ARVMOJFLOXVOMG-UHFFFAOYSA-N	368389	US10227342, Example 23	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618362	402365230							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727996	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCC3CCCN3C)ccc12	InChI=1S/C31H33N7O3/c1-5-29(39)34-21-8-11-28(40-4)26(15-21)35-31-33-18-20(17-32)30(36-31)25-19-38(3)27-16-23(9-10-24(25)27)41-14-12-22-7-6-13-37(22)2/h5,8-11,15-16,18-19,22H,1,6-7,12-14H2,2-4H3,(H,34,39)(H,33,35,36)	ARVMOJFLOXVOMG-UHFFFAOYSA-N	368389	US10227342, Example 23	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618362	402365230							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727998	COc1ccc(NC(=O)C=C)cc1Nc1ncc(C#N)c(n1)-c1cn(C)c2cc(OCCC3CCCN3C)ccc12	InChI=1S/C31H33N7O3/c1-5-29(39)34-21-8-11-28(40-4)26(15-21)35-31-33-18-20(17-32)30(36-31)25-19-38(3)27-16-23(9-10-24(25)27)41-14-12-22-7-6-13-37(22)2/h5,8-11,15-16,18-19,22H,1,6-7,12-14H2,2-4H3,(H,34,39)(H,33,35,36)	ARVMOJFLOXVOMG-UHFFFAOYSA-N	368389	US10227342, Example 23	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618362	402365230							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
727999	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12	InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)	DUYJMQONPNNFPI-UHFFFAOYSA-N	50029668	AZD-9291::Osimertinib::US10085983, Compound AZD-9291::US10227342, Example 24::US9890168, Compound AZD-9291::US11111233, Example AZD9291::WO2022090481, Example osimertinib::US20230322822, Compound AZD9291::US11896597, Compound AZD9291::US12410192, Compound Osimertinib	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029668&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496458	313065691			DB09330				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728000	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12	InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)	DUYJMQONPNNFPI-UHFFFAOYSA-N	50029668	AZD-9291::Osimertinib::US10085983, Compound AZD-9291::US10227342, Example 24::US9890168, Compound AZD-9291::US11111233, Example AZD9291::WO2022090481, Example osimertinib::US20230322822, Compound AZD9291::US11896597, Compound AZD9291::US12410192, Compound Osimertinib	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029668&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496458	313065691			DB09330				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728003	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12	InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)	DUYJMQONPNNFPI-UHFFFAOYSA-N	50029668	AZD-9291::Osimertinib::US10085983, Compound AZD-9291::US10227342, Example 24::US9890168, Compound AZD-9291::US11111233, Example AZD9291::WO2022090481, Example osimertinib::US20230322822, Compound AZD9291::US11896597, Compound AZD9291::US12410192, Compound Osimertinib	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029668&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496458	313065691			DB09330				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728004	COc1cc(N2CC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C26H27ClN8O2/c1-5-24(36)30-19-10-20(23(37-4)11-22(19)34-14-16(15-34)33(2)3)31-26-28-13-18(27)25(32-26)17-12-29-35-9-7-6-8-21(17)35/h5-13,16H,1,14-15H2,2-4H3,(H,30,36)(H,28,31,32)	RFZOHHKCEHQQBE-UHFFFAOYSA-N	50029686	CHEMBL3353405::US10227342, Example 25	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029686&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			101884761	313065704		CHEMBL3353405					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728006	COc1cc(N2CC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C26H27ClN8O2/c1-5-24(36)30-19-10-20(23(37-4)11-22(19)34-14-16(15-34)33(2)3)31-26-28-13-18(27)25(32-26)17-12-29-35-9-7-6-8-21(17)35/h5-13,16H,1,14-15H2,2-4H3,(H,30,36)(H,28,31,32)	RFZOHHKCEHQQBE-UHFFFAOYSA-N	50029686	CHEMBL3353405::US10227342, Example 25	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029686&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			101884761	313065704		CHEMBL3353405					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728007	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C26H27ClN8O2/c1-4-24(36)30-19-13-20(23(37-3)14-22(19)34-11-9-33(2)10-12-34)31-26-28-16-18(27)25(32-26)17-15-29-35-8-6-5-7-21(17)35/h4-8,13-16H,1,9-12H2,2-3H3,(H,30,36)(H,28,31,32)	SOSWXMRNLZWISK-UHFFFAOYSA-N	50029670	CHEMBL2426277::US10227342, Example 26	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029670	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029670&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			73292361	313065693		CHEMBL2426277					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728009	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C26H27ClN8O2/c1-4-24(36)30-19-13-20(23(37-3)14-22(19)34-11-9-33(2)10-12-34)31-26-28-16-18(27)25(32-26)17-15-29-35-8-6-5-7-21(17)35/h4-8,13-16H,1,9-12H2,2-3H3,(H,30,36)(H,28,31,32)	SOSWXMRNLZWISK-UHFFFAOYSA-N	50029670	CHEMBL2426277::US10227342, Example 26	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029670	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029670&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			73292361	313065693		CHEMBL2426277					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728010	COc1cc(N(C)CCN2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C29H34ClN9O2/c1-5-27(40)33-22-16-23(26(41-4)17-25(22)37(3)12-15-38-13-10-36(2)11-14-38)34-29-31-19-21(30)28(35-29)20-18-32-39-9-7-6-8-24(20)39/h5-9,16-19H,1,10-15H2,2-4H3,(H,33,40)(H,31,34,35)	TYBADZOQUJEUGT-UHFFFAOYSA-N	368393	US10227342, Example 27	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368393	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368393&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			86677274	402365234							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728012	COc1cc(N(C)CCN2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C29H34ClN9O2/c1-5-27(40)33-22-16-23(26(41-4)17-25(22)37(3)12-15-38-13-10-36(2)11-14-38)34-29-31-19-21(30)28(35-29)20-18-32-39-9-7-6-8-24(20)39/h5-9,16-19H,1,10-15H2,2-4H3,(H,33,40)(H,31,34,35)	TYBADZOQUJEUGT-UHFFFAOYSA-N	368393	US10227342, Example 27	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368393	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368393&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			86677274	402365234							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728013	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-30(41)35-25-16-26(29(43-8)17-28(25)39(6)15-14-38(4)5)36-33-34-18-23(32(42)44-20-21(2)3)31(37-33)24-19-40(7)27-13-11-10-12-22(24)27/h9-13,16-19,21H,1,14-15,20H2,2-8H3,(H,35,41)(H,34,36,37)	PDHCFKKUVBCBBI-UHFFFAOYSA-N	368394	US10227342, Example 28	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368394	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368394&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607823	402365235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728014	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-30(41)35-25-16-26(29(43-8)17-28(25)39(6)15-14-38(4)5)36-33-34-18-23(32(42)44-20-21(2)3)31(37-33)24-19-40(7)27-13-11-10-12-22(24)27/h9-13,16-19,21H,1,14-15,20H2,2-8H3,(H,35,41)(H,34,36,37)	PDHCFKKUVBCBBI-UHFFFAOYSA-N	368394	US10227342, Example 28	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368394	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368394&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607823	402365235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728016	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-30(41)35-25-16-26(29(43-8)17-28(25)39(6)15-14-38(4)5)36-33-34-18-23(32(42)44-20-21(2)3)31(37-33)24-19-40(7)27-13-11-10-12-22(24)27/h9-13,16-19,21H,1,14-15,20H2,2-8H3,(H,35,41)(H,34,36,37)	PDHCFKKUVBCBBI-UHFFFAOYSA-N	368394	US10227342, Example 28	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368394	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368394&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607823	402365235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728017	CCC(C)OC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-21(3)44-32(42)23-19-34-33(37-31(23)24-20-40(7)27-14-12-11-13-22(24)27)36-26-17-25(35-30(41)10-2)28(18-29(26)43-8)39(6)16-15-38(4)5/h10-14,17-21H,2,9,15-16H2,1,3-8H3,(H,35,41)(H,34,36,37)	LGCKLDWXEZDGJI-UHFFFAOYSA-N	368395	US10227342, Example 29	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368395&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618364	402365236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728018	CCC(C)OC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-21(3)44-32(42)23-19-34-33(37-31(23)24-20-40(7)27-14-12-11-13-22(24)27)36-26-17-25(35-30(41)10-2)28(18-29(26)43-8)39(6)16-15-38(4)5/h10-14,17-21H,2,9,15-16H2,1,3-8H3,(H,35,41)(H,34,36,37)	LGCKLDWXEZDGJI-UHFFFAOYSA-N	368395	US10227342, Example 29	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368395&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618364	402365236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728020	CCC(C)OC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-21(3)44-32(42)23-19-34-33(37-31(23)24-20-40(7)27-14-12-11-13-22(24)27)36-26-17-25(35-30(41)10-2)28(18-29(26)43-8)39(6)16-15-38(4)5/h10-14,17-21H,2,9,15-16H2,1,3-8H3,(H,35,41)(H,34,36,37)	LGCKLDWXEZDGJI-UHFFFAOYSA-N	368395	US10227342, Example 29	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368395&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618364	402365236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728021	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)34-24-15-25(27(41-7)16-26(24)38(6)14-13-37(4)5)35-31-33-18-22(30(40)42-19(2)3)29(36-31)21-17-32-23-12-10-9-11-20(21)23/h8-12,15-19,32H,1,13-14H2,2-7H3,(H,34,39)(H,33,35,36)	XZYDWQZDBVGQOH-UHFFFAOYSA-N	368396	US10227342, Example 30	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368396&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607816	402365237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728022	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)34-24-15-25(27(41-7)16-26(24)38(6)14-13-37(4)5)35-31-33-18-22(30(40)42-19(2)3)29(36-31)21-17-32-23-12-10-9-11-20(21)23/h8-12,15-19,32H,1,13-14H2,2-7H3,(H,34,39)(H,33,35,36)	XZYDWQZDBVGQOH-UHFFFAOYSA-N	368396	US10227342, Example 30	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368396&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607816	402365237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728025	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H37N7O4/c1-8-28(39)34-24-15-25(27(41-7)16-26(24)38(6)14-13-37(4)5)35-31-33-18-22(30(40)42-19(2)3)29(36-31)21-17-32-23-12-10-9-11-20(21)23/h8-12,15-19,32H,1,13-14H2,2-7H3,(H,34,39)(H,33,35,36)	XZYDWQZDBVGQOH-UHFFFAOYSA-N	368396	US10227342, Example 30	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368396&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607816	402365237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728026	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2c(OC)cccc12	InChI=1S/C33H41N7O5/c1-10-29(41)35-24-16-25(28(44-9)17-26(24)39(6)15-14-38(4)5)36-33-34-18-22(32(42)45-20(2)3)30(37-33)23-19-40(7)31-21(23)12-11-13-27(31)43-8/h10-13,16-20H,1,14-15H2,2-9H3,(H,35,41)(H,34,36,37)	RAMAQECDIGUIDQ-UHFFFAOYSA-N	368397	US10227342, Example 31	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368397&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607827	402365238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728027	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2c(OC)cccc12	InChI=1S/C33H41N7O5/c1-10-29(41)35-24-16-25(28(44-9)17-26(24)39(6)15-14-38(4)5)36-33-34-18-22(32(42)45-20(2)3)30(37-33)23-19-40(7)31-21(23)12-11-13-27(31)43-8/h10-13,16-20H,1,14-15H2,2-9H3,(H,35,41)(H,34,36,37)	RAMAQECDIGUIDQ-UHFFFAOYSA-N	368397	US10227342, Example 31	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368397&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607827	402365238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728029	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2c(OC)cccc12	InChI=1S/C33H41N7O5/c1-10-29(41)35-24-16-25(28(44-9)17-26(24)39(6)15-14-38(4)5)36-33-34-18-22(32(42)45-20(2)3)30(37-33)23-19-40(7)31-21(23)12-11-13-27(31)43-8/h10-13,16-20H,1,14-15H2,2-9H3,(H,35,41)(H,34,36,37)	RAMAQECDIGUIDQ-UHFFFAOYSA-N	368397	US10227342, Example 31	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368397&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607827	402365238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728030	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cnn2ccccc12	InChI=1S/C30H36N8O4/c1-8-27(39)33-22-15-23(26(41-7)16-25(22)37(6)14-13-36(4)5)34-30-31-17-21(29(40)42-19(2)3)28(35-30)20-18-32-38-12-10-9-11-24(20)38/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,39)(H,31,34,35)	MILNYSASBIETPM-UHFFFAOYSA-N	368398	US10227342, Example 32	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368398&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607779	402365239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728031	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cnn2ccccc12	InChI=1S/C30H36N8O4/c1-8-27(39)33-22-15-23(26(41-7)16-25(22)37(6)14-13-36(4)5)34-30-31-17-21(29(40)42-19(2)3)28(35-30)20-18-32-38-12-10-9-11-24(20)38/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,39)(H,31,34,35)	MILNYSASBIETPM-UHFFFAOYSA-N	368398	US10227342, Example 32	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368398&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607779	402365239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728033	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cnn2ccccc12	InChI=1S/C30H36N8O4/c1-8-27(39)33-22-15-23(26(41-7)16-25(22)37(6)14-13-36(4)5)34-30-31-17-21(29(40)42-19(2)3)28(35-30)20-18-32-38-12-10-9-11-24(20)38/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,39)(H,31,34,35)	MILNYSASBIETPM-UHFFFAOYSA-N	368398	US10227342, Example 32	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368398&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607779	402365239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728034	COc1cc(N(C)CCN(C)CCF)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H30ClFN8O2/c1-5-25(38)32-20-14-21(24(39-4)15-23(20)36(3)13-12-35(2)11-9-29)33-27-30-17-19(28)26(34-27)18-16-31-37-10-7-6-8-22(18)37/h5-8,10,14-17H,1,9,11-13H2,2-4H3,(H,32,38)(H,30,33,34)	DFBVGHPGSDFQCF-UHFFFAOYSA-N	368399	US10227342, Example 33	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368399	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368399&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618500	402365240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728036	COc1cc(N(C)CCN(C)CCF)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H30ClFN8O2/c1-5-25(38)32-20-14-21(24(39-4)15-23(20)36(3)13-12-35(2)11-9-29)33-27-30-17-19(28)26(34-27)18-16-31-37-10-7-6-8-22(18)37/h5-8,10,14-17H,1,9,11-13H2,2-4H3,(H,32,38)(H,30,33,34)	DFBVGHPGSDFQCF-UHFFFAOYSA-N	368399	US10227342, Example 33	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368399	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368399&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618500	402365240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728037	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ncccc12	InChI=1S/C31H38N8O4/c1-9-27(40)34-23-15-24(26(42-8)16-25(23)38(6)14-13-37(4)5)35-31-33-17-21(30(41)43-19(2)3)28(36-31)22-18-39(7)29-20(22)11-10-12-32-29/h9-12,15-19H,1,13-14H2,2-8H3,(H,34,40)(H,33,35,36)	RPQIJNRGVLJNCN-UHFFFAOYSA-N	368400	US10227342, Example 34	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368400&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607840	402365241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728038	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ncccc12	InChI=1S/C31H38N8O4/c1-9-27(40)34-23-15-24(26(42-8)16-25(23)38(6)14-13-37(4)5)35-31-33-17-21(30(41)43-19(2)3)28(36-31)22-18-39(7)29-20(22)11-10-12-32-29/h9-12,15-19H,1,13-14H2,2-8H3,(H,34,40)(H,33,35,36)	RPQIJNRGVLJNCN-UHFFFAOYSA-N	368400	US10227342, Example 34	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368400&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607840	402365241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728041	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ncccc12	InChI=1S/C31H38N8O4/c1-9-27(40)34-23-15-24(26(42-8)16-25(23)38(6)14-13-37(4)5)35-31-33-17-21(30(41)43-19(2)3)28(36-31)22-18-39(7)29-20(22)11-10-12-32-29/h9-12,15-19H,1,13-14H2,2-8H3,(H,34,40)(H,33,35,36)	RPQIJNRGVLJNCN-UHFFFAOYSA-N	368400	US10227342, Example 34	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368400&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607840	402365241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728042	COc1cc(N(C)C[C@@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368401	US10227342, Example 35	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130208457	402365242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728043	COc1cc(N(C)C[C@@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368401	US10227342, Example 35	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130208457	402365242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728046	COc1cc(N(C)C[C@@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368401	US10227342, Example 35	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130208457	402365242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728047	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368402	US10227342, Example 36	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130208458	402365243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728048	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368402	US10227342, Example 36	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130208458	402365243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728051	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-16-27(30(44-7)17-29(26)40(5)19-22-12-11-15-39(22)4)37-34-35-18-24(33(43)45-21(2)3)32(38-34)25-20-41(6)28-14-10-9-13-23(25)28/h8-10,13-14,16-18,20-22H,1,11-12,15,19H2,2-7H3,(H,36,42)(H,35,37,38)	MILBIPKHYWBIPY-UHFFFAOYSA-N	368402	US10227342, Example 36	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130208458	402365243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728052	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)O[C@@H]2CCOC2)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O5/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)14-13-38(2)3)36-33-34-18-23(32(42)45-21-12-15-44-20-21)31(37-33)24-19-40(5)27-11-9-8-10-22(24)27/h7-11,16-19,21H,1,12-15,20H2,2-6H3,(H,35,41)(H,34,36,37)	LCELKAHKZFIDGW-UHFFFAOYSA-N	368403	US10227342, Example 37	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618391	402365244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728053	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)O[C@@H]2CCOC2)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O5/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)14-13-38(2)3)36-33-34-18-23(32(42)45-21-12-15-44-20-21)31(37-33)24-19-40(5)27-11-9-8-10-22(24)27/h7-11,16-19,21H,1,12-15,20H2,2-6H3,(H,35,41)(H,34,36,37)	LCELKAHKZFIDGW-UHFFFAOYSA-N	368403	US10227342, Example 37	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618391	402365244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728055	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)O[C@@H]2CCOC2)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O5/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)14-13-38(2)3)36-33-34-18-23(32(42)45-21-12-15-44-20-21)31(37-33)24-19-40(5)27-11-9-8-10-22(24)27/h7-11,16-19,21H,1,12-15,20H2,2-6H3,(H,35,41)(H,34,36,37)	LCELKAHKZFIDGW-UHFFFAOYSA-N	368403	US10227342, Example 37	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618391	402365244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728056	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC#N)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C31H34N8O4/c1-7-28(40)34-23-16-24(27(42-6)17-26(23)38(4)14-13-37(2)3)35-31-33-18-21(30(41)43-15-12-32)29(36-31)22-19-39(5)25-11-9-8-10-20(22)25/h7-11,16-19H,1,13-15H2,2-6H3,(H,34,40)(H,33,35,36)	XVMKRUKKTIHQDU-UHFFFAOYSA-N	368404	US10227342, Example 38	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618537	402365245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728057	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC#N)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C31H34N8O4/c1-7-28(40)34-23-16-24(27(42-6)17-26(23)38(4)14-13-37(2)3)35-31-33-18-21(30(41)43-15-12-32)29(36-31)22-19-39(5)25-11-9-8-10-20(22)25/h7-11,16-19H,1,13-15H2,2-6H3,(H,34,40)(H,33,35,36)	XVMKRUKKTIHQDU-UHFFFAOYSA-N	368404	US10227342, Example 38	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618537	402365245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728059	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC#N)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C31H34N8O4/c1-7-28(40)34-23-16-24(27(42-6)17-26(23)38(4)14-13-37(2)3)35-31-33-18-21(30(41)43-15-12-32)29(36-31)22-19-39(5)25-11-9-8-10-20(22)25/h7-11,16-19H,1,13-15H2,2-6H3,(H,34,40)(H,33,35,36)	XVMKRUKKTIHQDU-UHFFFAOYSA-N	368404	US10227342, Example 38	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618537	402365245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728060	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(NC(=O)C(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H40N8O3/c1-9-29(41)34-23-16-24(28(43-8)17-27(23)39(6)15-14-38(4)5)36-32-33-18-25(35-31(42)20(2)3)30(37-32)22-19-40(7)26-13-11-10-12-21(22)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,41)(H,35,42)(H,33,36,37)	BWWSNXDEZXDDNB-UHFFFAOYSA-N	368405	US10227342, Example 39	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607815	402365246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728061	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(NC(=O)C(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H40N8O3/c1-9-29(41)34-23-16-24(28(43-8)17-27(23)39(6)15-14-38(4)5)36-32-33-18-25(35-31(42)20(2)3)30(37-32)22-19-40(7)26-13-11-10-12-21(22)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,41)(H,35,42)(H,33,36,37)	BWWSNXDEZXDDNB-UHFFFAOYSA-N	368405	US10227342, Example 39	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607815	402365246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728063	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(NC(=O)C(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C32H40N8O3/c1-9-29(41)34-23-16-24(28(43-8)17-27(23)39(6)15-14-38(4)5)36-32-33-18-25(35-31(42)20(2)3)30(37-32)22-19-40(7)26-13-11-10-12-21(22)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,41)(H,35,42)(H,33,36,37)	BWWSNXDEZXDDNB-UHFFFAOYSA-N	368405	US10227342, Example 39	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607815	402365246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728064	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(N(C)C(=O)C(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H42N8O3/c1-10-30(42)35-24-17-25(29(44-9)18-27(24)39(6)16-15-38(4)5)36-33-34-19-28(41(8)32(43)21(2)3)31(37-33)23-20-40(7)26-14-12-11-13-22(23)26/h10-14,17-21H,1,15-16H2,2-9H3,(H,35,42)(H,34,36,37)	IOKVRNZOKGJSMC-UHFFFAOYSA-N	368407	US10227342, Example 40	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618178	402365248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728065	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(N(C)C(=O)C(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H42N8O3/c1-10-30(42)35-24-17-25(29(44-9)18-27(24)39(6)16-15-38(4)5)36-33-34-19-28(41(8)32(43)21(2)3)31(37-33)23-20-40(7)26-14-12-11-13-22(23)26/h10-14,17-21H,1,15-16H2,2-9H3,(H,35,42)(H,34,36,37)	IOKVRNZOKGJSMC-UHFFFAOYSA-N	368407	US10227342, Example 40	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618178	402365248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728067	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(N(C)C(=O)C(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H42N8O3/c1-10-30(42)35-24-17-25(29(44-9)18-27(24)39(6)16-15-38(4)5)36-33-34-19-28(41(8)32(43)21(2)3)31(37-33)23-20-40(7)26-14-12-11-13-22(23)26/h10-14,17-21H,1,15-16H2,2-9H3,(H,35,42)(H,34,36,37)	IOKVRNZOKGJSMC-UHFFFAOYSA-N	368407	US10227342, Example 40	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618178	402365248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728068	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(NC(=O)C(C)(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H42N8O3/c1-10-29(42)35-23-17-24(28(44-9)18-27(23)40(7)16-15-39(5)6)37-32-34-19-25(36-31(43)33(2,3)4)30(38-32)22-20-41(8)26-14-12-11-13-21(22)26/h10-14,17-20H,1,15-16H2,2-9H3,(H,35,42)(H,36,43)(H,34,37,38)	DAMWSKUEQIQQDB-UHFFFAOYSA-N	368408	US10227342, Example 41	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618555	402365249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728069	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(NC(=O)C(C)(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H42N8O3/c1-10-29(42)35-23-17-24(28(44-9)18-27(23)40(7)16-15-39(5)6)37-32-34-19-25(36-31(43)33(2,3)4)30(38-32)22-20-41(8)26-14-12-11-13-21(22)26/h10-14,17-20H,1,15-16H2,2-9H3,(H,35,42)(H,36,43)(H,34,37,38)	DAMWSKUEQIQQDB-UHFFFAOYSA-N	368408	US10227342, Example 41	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618555	402365249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728071	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(NC(=O)C(C)(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C33H42N8O3/c1-10-29(42)35-23-17-24(28(44-9)18-27(23)40(7)16-15-39(5)6)37-32-34-19-25(36-31(43)33(2,3)4)30(38-32)22-20-41(8)26-14-12-11-13-21(22)26/h10-14,17-20H,1,15-16H2,2-9H3,(H,35,42)(H,36,43)(H,34,37,38)	DAMWSKUEQIQQDB-UHFFFAOYSA-N	368408	US10227342, Example 41	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618555	402365249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728072	COc1cc(OC)c(Nc2ncc(NC(=O)C(C)(C)C)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C29H32N6O4/c1-8-25(36)31-19-13-20(24(39-7)14-23(19)38-6)33-28-30-15-21(32-27(37)29(2,3)4)26(34-28)18-16-35(5)22-12-10-9-11-17(18)22/h8-16H,1H2,2-7H3,(H,31,36)(H,32,37)(H,30,33,34)	OPIDFLHFDHIHHO-UHFFFAOYSA-N	368409	US10227342, Example 42	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607780	402365250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728073	COc1cc(OC)c(Nc2ncc(NC(=O)C(C)(C)C)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C29H32N6O4/c1-8-25(36)31-19-13-20(24(39-7)14-23(19)38-6)33-28-30-15-21(32-27(37)29(2,3)4)26(34-28)18-16-35(5)22-12-10-9-11-17(18)22/h8-16H,1H2,2-7H3,(H,31,36)(H,32,37)(H,30,33,34)	OPIDFLHFDHIHHO-UHFFFAOYSA-N	368409	US10227342, Example 42	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607780	402365250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728075	COc1cc(OC)c(Nc2ncc(NC(=O)C(C)(C)C)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C29H32N6O4/c1-8-25(36)31-19-13-20(24(39-7)14-23(19)38-6)33-28-30-15-21(32-27(37)29(2,3)4)26(34-28)18-16-35(5)22-12-10-9-11-17(18)22/h8-16H,1H2,2-7H3,(H,31,36)(H,32,37)(H,30,33,34)	OPIDFLHFDHIHHO-UHFFFAOYSA-N	368409	US10227342, Example 42	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607780	402365250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728076	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2c3CCCc3ccc12	InChI=1S/C31H36ClN7O2/c1-7-28(40)34-24-15-25(27(41-6)16-26(24)38(4)14-13-37(2)3)35-31-33-17-23(32)29(36-31)22-18-39(5)30-20-10-8-9-19(20)11-12-21(22)30/h7,11-12,15-18H,1,8-10,13-14H2,2-6H3,(H,34,40)(H,33,35,36)	YNFJPEVWUUGZMO-UHFFFAOYSA-N	368410	N-(5-((5-chloro-4-(1-methyl-1,6,7,8-tetrahydrocyclopenta[g]indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide::US10227342, Example 43	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368410	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368410&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607819	402365251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728078	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2c3CCCc3ccc12	InChI=1S/C31H36ClN7O2/c1-7-28(40)34-24-15-25(27(41-6)16-26(24)38(4)14-13-37(2)3)35-31-33-17-23(32)29(36-31)22-18-39(5)30-20-10-8-9-19(20)11-12-21(22)30/h7,11-12,15-18H,1,8-10,13-14H2,2-6H3,(H,34,40)(H,33,35,36)	YNFJPEVWUUGZMO-UHFFFAOYSA-N	368410	N-(5-((5-chloro-4-(1-methyl-1,6,7,8-tetrahydrocyclopenta[g]indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide::US10227342, Example 43	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368410	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368410&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607819	402365251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728079	CCOC[C@@H](CN(C)C)Oc1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C |r|	InChI=1S/C30H35ClN6O4/c1-7-28(38)33-24-13-23(26(39-6)14-27(24)41-19(16-36(3)4)18-40-8-2)34-30-32-15-22(31)29(35-30)21-17-37(5)25-12-10-9-11-20(21)25/h7,9-15,17,19H,1,8,16,18H2,2-6H3,(H,33,38)(H,32,34,35)	YWBBHIINYSKHPR-UHFFFAOYSA-N	368411	US10227342, Example 44	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368411	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130218145	402365252							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728081	CCOC[C@@H](CN(C)C)Oc1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C |r|	InChI=1S/C30H35ClN6O4/c1-7-28(38)33-24-13-23(26(39-6)14-27(24)41-19(16-36(3)4)18-40-8-2)34-30-32-15-22(31)29(35-30)21-17-37(5)25-12-10-9-11-20(21)25/h7,9-15,17,19H,1,8,16,18H2,2-6H3,(H,33,38)(H,32,34,35)	YWBBHIINYSKHPR-UHFFFAOYSA-N	368411	US10227342, Example 44	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368411	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130218145	402365252							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728082	COc1cc(C#CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C28H27ClN6O2/c1-6-26(36)31-22-15-23(25(37-5)14-18(22)10-9-13-34(2)3)32-28-30-16-21(29)27(33-28)20-17-35(4)24-12-8-7-11-19(20)24/h6-8,11-12,14-17H,1,13H2,2-5H3,(H,31,36)(H,30,32,33)	ZCHFJEJVPVANLH-UHFFFAOYSA-N	368412	US10227342, Example 45	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368412	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368412&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618540	402365253							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728084	COc1cc(C#CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C28H27ClN6O2/c1-6-26(36)31-22-15-23(25(37-5)14-18(22)10-9-13-34(2)3)32-28-30-16-21(29)27(33-28)20-17-35(4)24-12-8-7-11-19(20)24/h6-8,11-12,14-17H,1,13H2,2-5H3,(H,31,36)(H,30,32,33)	ZCHFJEJVPVANLH-UHFFFAOYSA-N	368412	US10227342, Example 45	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368412	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368412&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618540	402365253							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728085	COc1cc(C#CC(C)(C)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C30H31ClN6O2/c1-8-27(38)33-23-16-24(26(39-7)15-19(23)13-14-30(2,3)36(4)5)34-29-32-17-22(31)28(35-29)21-18-37(6)25-12-10-9-11-20(21)25/h8-12,15-18H,1H2,2-7H3,(H,33,38)(H,32,34,35)	WPRWQFVKZVSYHV-UHFFFAOYSA-N	368414	US10227342, Example 46	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368414	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368414&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618523	402365255							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728087	COc1cc(C#CC(C)(C)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C30H31ClN6O2/c1-8-27(38)33-23-16-24(26(39-7)15-19(23)13-14-30(2,3)36(4)5)34-29-32-17-22(31)28(35-29)21-18-37(6)25-12-10-9-11-20(21)25/h8-12,15-18H,1H2,2-7H3,(H,33,38)(H,32,34,35)	WPRWQFVKZVSYHV-UHFFFAOYSA-N	368414	US10227342, Example 46	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368414	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368414&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618523	402365255							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728088	CCN(CC)CC(COC)Oc1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnn3ccccc23)cc1NC(=O)C=C	InChI=1S/C29H34ClN7O4/c1-6-27(38)33-23-13-22(25(40-5)14-26(23)41-19(18-39-4)17-36(7-2)8-3)34-29-31-16-21(30)28(35-29)20-15-32-37-12-10-9-11-24(20)37/h6,9-16,19H,1,7-8,17-18H2,2-5H3,(H,33,38)(H,31,34,35)	AUWBIBQQHHAHMY-UHFFFAOYSA-N	368415	US10227342, Example 47	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368415	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368415&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618530	402365256							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728090	CCN(CC)CC(COC)Oc1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnn3ccccc23)cc1NC(=O)C=C	InChI=1S/C29H34ClN7O4/c1-6-27(38)33-23-13-22(25(40-5)14-26(23)41-19(18-39-4)17-36(7-2)8-3)34-29-31-16-21(30)28(35-29)20-15-32-37-12-10-9-11-24(20)37/h6,9-16,19H,1,7-8,17-18H2,2-5H3,(H,33,38)(H,31,34,35)	AUWBIBQQHHAHMY-UHFFFAOYSA-N	368415	US10227342, Example 47	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368415	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368415&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618530	402365256							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728091	COCC(CN(C)C)Oc1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnn3ccccc23)cc1NC(=O)C=C	InChI=1S/C27H30ClN7O4/c1-6-25(36)31-21-11-20(23(38-5)12-24(21)39-17(16-37-4)15-34(2)3)32-27-29-14-19(28)26(33-27)18-13-30-35-10-8-7-9-22(18)35/h6-14,17H,1,15-16H2,2-5H3,(H,31,36)(H,29,32,33)	WUCBDXKWNQHPAF-UHFFFAOYSA-N	368416	US10227342, Example 48	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618563	402365257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728093	COCC(CN(C)C)Oc1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnn3ccccc23)cc1NC(=O)C=C	InChI=1S/C27H30ClN7O4/c1-6-25(36)31-21-11-20(23(38-5)12-24(21)39-17(16-37-4)15-34(2)3)32-27-29-14-19(28)26(33-27)18-13-30-35-10-8-7-9-22(18)35/h6-14,17H,1,15-16H2,2-5H3,(H,31,36)(H,29,32,33)	WUCBDXKWNQHPAF-UHFFFAOYSA-N	368416	US10227342, Example 48	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618563	402365257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728094	COc1cc(OCCN2CCCC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H28ClN7O3/c1-3-25(36)31-21-14-20(23(37-2)15-24(21)38-13-12-34-9-6-7-10-34)32-27-29-17-19(28)26(33-27)18-16-30-35-11-5-4-8-22(18)35/h3-5,8,11,14-17H,1,6-7,9-10,12-13H2,2H3,(H,31,36)(H,29,32,33)	IAHSKZVEEYWBMS-UHFFFAOYSA-N	368417	US10227342, Example 49	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618394	402365258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728096	COc1cc(OCCN2CCCC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H28ClN7O3/c1-3-25(36)31-21-14-20(23(37-2)15-24(21)38-13-12-34-9-6-7-10-34)32-27-29-17-19(28)26(33-27)18-16-30-35-11-5-4-8-22(18)35/h3-5,8,11,14-17H,1,6-7,9-10,12-13H2,2H3,(H,31,36)(H,29,32,33)	IAHSKZVEEYWBMS-UHFFFAOYSA-N	368417	US10227342, Example 49	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618394	402365258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728097	COc1cc(OCCN2CCOCC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H28ClN7O4/c1-3-25(36)31-21-14-20(23(37-2)15-24(21)39-13-10-34-8-11-38-12-9-34)32-27-29-17-19(28)26(33-27)18-16-30-35-7-5-4-6-22(18)35/h3-7,14-17H,1,8-13H2,2H3,(H,31,36)(H,29,32,33)	SAKKNWFGXJPZKT-UHFFFAOYSA-N	368418	US10227342, Example 50	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618549	402365259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728099	COc1cc(OCCN2CCOCC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H28ClN7O4/c1-3-25(36)31-21-14-20(23(37-2)15-24(21)39-13-10-34-8-11-38-12-9-34)32-27-29-17-19(28)26(33-27)18-16-30-35-7-5-4-6-22(18)35/h3-7,14-17H,1,8-13H2,2H3,(H,31,36)(H,29,32,33)	SAKKNWFGXJPZKT-UHFFFAOYSA-N	368418	US10227342, Example 50	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618549	402365259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728100	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C25H26ClN7O3/c1-5-23(34)29-19-12-18(21(35-4)13-22(19)36-11-10-32(2)3)30-25-27-15-17(26)24(31-25)16-14-28-33-9-7-6-8-20(16)33/h5-9,12-15H,1,10-11H2,2-4H3,(H,29,34)(H,27,30,31)	CQHOBDXHDPNDSA-UHFFFAOYSA-N	368419	US10227342, Example 51	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607777	402365260							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728101	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C25H26ClN7O3/c1-5-23(34)29-19-12-18(21(35-4)13-22(19)36-11-10-32(2)3)30-25-27-15-17(26)24(31-25)16-14-28-33-9-7-6-8-20(16)33/h5-9,12-15H,1,10-11H2,2-4H3,(H,29,34)(H,27,30,31)	CQHOBDXHDPNDSA-UHFFFAOYSA-N	368419	US10227342, Example 51	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607777	402365260							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728103	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C25H26ClN7O3/c1-5-23(34)29-19-12-18(21(35-4)13-22(19)36-11-10-32(2)3)30-25-27-15-17(26)24(31-25)16-14-28-33-9-7-6-8-20(16)33/h5-9,12-15H,1,10-11H2,2-4H3,(H,29,34)(H,27,30,31)	CQHOBDXHDPNDSA-UHFFFAOYSA-N	368419	US10227342, Example 51	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607777	402365260							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728104	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C26H29ClN8O2/c1-6-24(36)30-19-13-20(23(37-5)14-22(19)34(4)12-11-33(2)3)31-26-28-16-18(27)25(32-26)17-15-29-35-10-8-7-9-21(17)35/h6-10,13-16H,1,11-12H2,2-5H3,(H,30,36)(H,28,31,32)	IEPKZTQXMCCRFJ-UHFFFAOYSA-N	50029685	CHEMBL3353404::US10227342, Example 52	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029685&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			101884762	313065703		CHEMBL3353404					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728105	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C26H29ClN8O2/c1-6-24(36)30-19-13-20(23(37-5)14-22(19)34(4)12-11-33(2)3)31-26-28-16-18(27)25(32-26)17-15-29-35-10-8-7-9-21(17)35/h6-10,13-16H,1,11-12H2,2-5H3,(H,30,36)(H,28,31,32)	IEPKZTQXMCCRFJ-UHFFFAOYSA-N	50029685	CHEMBL3353404::US10227342, Example 52	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029685&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			101884762	313065703		CHEMBL3353404					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728108	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C26H29ClN8O2/c1-6-24(36)30-19-13-20(23(37-5)14-22(19)34(4)12-11-33(2)3)31-26-28-16-18(27)25(32-26)17-15-29-35-10-8-7-9-21(17)35/h6-10,13-16H,1,11-12H2,2-5H3,(H,30,36)(H,28,31,32)	IEPKZTQXMCCRFJ-UHFFFAOYSA-N	50029685	CHEMBL3353404::US10227342, Example 52	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029685&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			101884762	313065703		CHEMBL3353404					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728109	CCN(CC)CCN(C)c1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnn3ccccc23)cc1NC(=O)C=C	InChI=1S/C28H33ClN8O2/c1-6-26(38)32-21-15-22(25(39-5)16-24(21)35(4)13-14-36(7-2)8-3)33-28-30-18-20(29)27(34-28)19-17-31-37-12-10-9-11-23(19)37/h6,9-12,15-18H,1,7-8,13-14H2,2-5H3,(H,32,38)(H,30,33,34)	NGMZVIJKHMLMTJ-UHFFFAOYSA-N	368421	US10227342, Example 53	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368421&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618225	402365262							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728111	CCN(CC)CCN(C)c1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnn3ccccc23)cc1NC(=O)C=C	InChI=1S/C28H33ClN8O2/c1-6-26(38)32-21-15-22(25(39-5)16-24(21)35(4)13-14-36(7-2)8-3)33-28-30-18-20(29)27(34-28)19-17-31-37-12-10-9-11-23(19)37/h6,9-12,15-18H,1,7-8,13-14H2,2-5H3,(H,32,38)(H,30,33,34)	NGMZVIJKHMLMTJ-UHFFFAOYSA-N	368421	US10227342, Example 53	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368421&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618225	402365262							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728112	COc1cc(N(C)CCN2CCOCC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C28H31ClN8O3/c1-4-26(38)32-21-15-22(25(39-3)16-24(21)35(2)9-10-36-11-13-40-14-12-36)33-28-30-18-20(29)27(34-28)19-17-31-37-8-6-5-7-23(19)37/h4-8,15-18H,1,9-14H2,2-3H3,(H,32,38)(H,30,33,34)	TUCDHJPGHHUXIH-UHFFFAOYSA-N	368422	US10227342, Example 54	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368422	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368422&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118037178	402365263							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728114	COc1cc(N(C)CCN2CCOCC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C28H31ClN8O3/c1-4-26(38)32-21-15-22(25(39-3)16-24(21)35(2)9-10-36-11-13-40-14-12-36)33-28-30-18-20(29)27(34-28)19-17-31-37-8-6-5-7-23(19)37/h4-8,15-18H,1,9-14H2,2-3H3,(H,32,38)(H,30,33,34)	TUCDHJPGHHUXIH-UHFFFAOYSA-N	368422	US10227342, Example 54	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368422	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368422&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118037178	402365263							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728115	COc1cc(N2CCC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H29ClN8O2/c1-5-25(37)31-20-12-21(24(38-4)13-23(20)35-11-9-17(16-35)34(2)3)32-27-29-15-19(28)26(33-27)18-14-30-36-10-7-6-8-22(18)36/h5-8,10,12-15,17H,1,9,11,16H2,2-4H3,(H,31,37)(H,29,32,33)	NBRHHKSETRXRCP-UHFFFAOYSA-N	368423	US10227342, Example 55	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368423&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607806	402365264							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728116	COc1cc(N2CCC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H29ClN8O2/c1-5-25(37)31-20-12-21(24(38-4)13-23(20)35-11-9-17(16-35)34(2)3)32-27-29-15-19(28)26(33-27)18-14-30-36-10-7-6-8-22(18)36/h5-8,10,12-15,17H,1,9,11,16H2,2-4H3,(H,31,37)(H,29,32,33)	NBRHHKSETRXRCP-UHFFFAOYSA-N	368423	US10227342, Example 55	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368423&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607806	402365264							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728118	COc1cc(N2CCC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12	InChI=1S/C27H29ClN8O2/c1-5-25(37)31-20-12-21(24(38-4)13-23(20)35-11-9-17(16-35)34(2)3)32-27-29-15-19(28)26(33-27)18-14-30-36-10-7-6-8-22(18)36/h5-8,10,12-15,17H,1,9,11,16H2,2-4H3,(H,31,37)(H,29,32,33)	NBRHHKSETRXRCP-UHFFFAOYSA-N	368423	US10227342, Example 55	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368423&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607806	402365264							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728119	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C27H30ClN7O2/c1-6-25(36)31-21-13-22(24(37-5)14-23(21)35(4)12-11-34(2)3)32-27-30-16-19(28)26(33-27)18-15-29-20-10-8-7-9-17(18)20/h6-10,13-16,29H,1,11-12H2,2-5H3,(H,31,36)(H,30,32,33)	SUPQPCQJBYPRPC-UHFFFAOYSA-N	50029664	CHEMBL3353408::US10227342, Example 56	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029664&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			78357783	313065689		CHEMBL3353408					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728120	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C27H30ClN7O2/c1-6-25(36)31-21-13-22(24(37-5)14-23(21)35(4)12-11-34(2)3)32-27-30-16-19(28)26(33-27)18-15-29-20-10-8-7-9-17(18)20/h6-10,13-16,29H,1,11-12H2,2-5H3,(H,31,36)(H,30,32,33)	SUPQPCQJBYPRPC-UHFFFAOYSA-N	50029664	CHEMBL3353408::US10227342, Example 56	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029664&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			78357783	313065689		CHEMBL3353408					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728123	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C27H30ClN7O2/c1-6-25(36)31-21-13-22(24(37-5)14-23(21)35(4)12-11-34(2)3)32-27-30-16-19(28)26(33-27)18-15-29-20-10-8-7-9-17(18)20/h6-10,13-16,29H,1,11-12H2,2-5H3,(H,31,36)(H,30,32,33)	SUPQPCQJBYPRPC-UHFFFAOYSA-N	50029664	CHEMBL3353408::US10227342, Example 56	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029664&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			78357783	313065689		CHEMBL3353408					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728124	CNCCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C27H31N7O2/c1-6-26(35)30-21-15-22(25(36-5)16-24(21)33(3)14-13-28-2)32-27-29-12-11-20(31-27)19-17-34(4)23-10-8-7-9-18(19)23/h6-12,15-17,28H,1,13-14H2,2-5H3,(H,30,35)(H,29,31,32)	ZROCWKZRGJYPTG-UHFFFAOYSA-N	50029687	CHEMBL3353412::US10227342, Example 57	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029687&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496459	103938719		CHEMBL3353412					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728125	CNCCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C27H31N7O2/c1-6-26(35)30-21-15-22(25(36-5)16-24(21)33(3)14-13-28-2)32-27-29-12-11-20(31-27)19-17-34(4)23-10-8-7-9-18(19)23/h6-12,15-17,28H,1,13-14H2,2-5H3,(H,30,35)(H,29,31,32)	ZROCWKZRGJYPTG-UHFFFAOYSA-N	50029687	CHEMBL3353412::US10227342, Example 57	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029687&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496459	103938719		CHEMBL3353412					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728128	CNCCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C27H31N7O2/c1-6-26(35)30-21-15-22(25(36-5)16-24(21)33(3)14-13-28-2)32-27-29-12-11-20(31-27)19-17-34(4)23-10-8-7-9-18(19)23/h6-12,15-17,28H,1,13-14H2,2-5H3,(H,30,35)(H,29,31,32)	ZROCWKZRGJYPTG-UHFFFAOYSA-N	50029687	CHEMBL3353412::US10227342, Example 57	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029687&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496459	103938719		CHEMBL3353412					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728129	CNCCN(C)c1cc(OC)c(Nc2ncc(C(=O)OC(C)C)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C31H37N7O4/c1-8-28(39)34-23-15-24(27(41-7)16-26(23)37(5)14-13-32-4)35-31-33-17-21(30(40)42-19(2)3)29(36-31)22-18-38(6)25-12-10-9-11-20(22)25/h8-12,15-19,32H,1,13-14H2,2-7H3,(H,34,39)(H,33,35,36)	MRBXRYTXQWBQSS-UHFFFAOYSA-N	368426	US10227342, Example 58	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368426&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607765	402365267							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728130	CNCCN(C)c1cc(OC)c(Nc2ncc(C(=O)OC(C)C)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C31H37N7O4/c1-8-28(39)34-23-15-24(27(41-7)16-26(23)37(5)14-13-32-4)35-31-33-17-21(30(40)42-19(2)3)29(36-31)22-18-38(6)25-12-10-9-11-20(22)25/h8-12,15-19,32H,1,13-14H2,2-7H3,(H,34,39)(H,33,35,36)	MRBXRYTXQWBQSS-UHFFFAOYSA-N	368426	US10227342, Example 58	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368426&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607765	402365267							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728133	CNCCN(C)c1cc(OC)c(Nc2ncc(C(=O)OC(C)C)c(n2)-c2cn(C)c3ccccc23)cc1NC(=O)C=C	InChI=1S/C31H37N7O4/c1-8-28(39)34-23-15-24(27(41-7)16-26(23)37(5)14-13-32-4)35-31-33-17-21(30(40)42-19(2)3)29(36-31)22-18-38(6)25-12-10-9-11-20(22)25/h8-12,15-19,32H,1,13-14H2,2-7H3,(H,34,39)(H,33,35,36)	MRBXRYTXQWBQSS-UHFFFAOYSA-N	368426	US10227342, Example 58	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368426&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607765	402365267							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728134	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1nn(C)c2ccccc12	InChI=1S/C31H38N8O4/c1-9-27(40)33-22-16-23(26(42-8)17-25(22)38(6)15-14-37(4)5)34-31-32-18-21(30(41)43-19(2)3)28(35-31)29-20-12-10-11-13-24(20)39(7)36-29/h9-13,16-19H,1,14-15H2,2-8H3,(H,33,40)(H,32,34,35)	BDKAGMNAOQQPRC-UHFFFAOYSA-N	368427	US10227342, Example 59	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607801	402365268							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728135	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1nn(C)c2ccccc12	InChI=1S/C31H38N8O4/c1-9-27(40)33-22-16-23(26(42-8)17-25(22)38(6)15-14-37(4)5)34-31-32-18-21(30(41)43-19(2)3)28(35-31)29-20-12-10-11-13-24(20)39(7)36-29/h9-13,16-19H,1,14-15H2,2-8H3,(H,33,40)(H,32,34,35)	BDKAGMNAOQQPRC-UHFFFAOYSA-N	368427	US10227342, Example 59	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607801	402365268							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728137	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1nn(C)c2ccccc12	InChI=1S/C31H38N8O4/c1-9-27(40)33-22-16-23(26(42-8)17-25(22)38(6)15-14-37(4)5)34-31-32-18-21(30(41)43-19(2)3)28(35-31)29-20-12-10-11-13-24(20)39(7)36-29/h9-13,16-19H,1,14-15H2,2-8H3,(H,33,40)(H,32,34,35)	BDKAGMNAOQQPRC-UHFFFAOYSA-N	368427	US10227342, Example 59	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607801	402365268							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728138	CCC(=O)Nc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1nn(C)c2ccccc12	InChI=1S/C30H37N9O3/c1-8-26(40)32-20-16-21(25(42-7)17-24(20)38(5)15-14-37(3)4)34-30-31-18-22(33-27(41)9-2)29(35-30)28-19-12-10-11-13-23(19)39(6)36-28/h8,10-13,16-18H,1,9,14-15H2,2-7H3,(H,32,40)(H,33,41)(H,31,34,35)	OORUIWCUQGVFFP-UHFFFAOYSA-N	368428	US10227342, Example 60	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618564	402365269							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728139	CCC(=O)Nc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1nn(C)c2ccccc12	InChI=1S/C30H37N9O3/c1-8-26(40)32-20-16-21(25(42-7)17-24(20)38(5)15-14-37(3)4)34-30-31-18-22(33-27(41)9-2)29(35-30)28-19-12-10-11-13-23(19)39(6)36-28/h8,10-13,16-18H,1,9,14-15H2,2-7H3,(H,32,40)(H,33,41)(H,31,34,35)	OORUIWCUQGVFFP-UHFFFAOYSA-N	368428	US10227342, Example 60	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618564	402365269							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728141	CCC(=O)Nc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1nn(C)c2ccccc12	InChI=1S/C30H37N9O3/c1-8-26(40)32-20-16-21(25(42-7)17-24(20)38(5)15-14-37(3)4)34-30-31-18-22(33-27(41)9-2)29(35-30)28-19-12-10-11-13-23(19)39(6)36-28/h8,10-13,16-18H,1,9,14-15H2,2-7H3,(H,32,40)(H,33,41)(H,31,34,35)	OORUIWCUQGVFFP-UHFFFAOYSA-N	368428	US10227342, Example 60	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618564	402365269							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728142	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1ccc2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-17-26(29(43-6)18-28(25)39(5)20-23-12-10-15-38(23)4)36-33-34-19-24(32(42)44-21(2)3)31(37-33)40-16-14-22-11-8-9-13-27(22)40/h7-9,11,13-14,16-19,21,23H,1,10,12,15,20H2,2-6H3,(H,35,41)(H,34,36,37)	QIQBFGLTZKXCOD-UHFFFAOYSA-N	368429	US10227342, Example 61	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797255	402365270							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728143	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1ccc2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-17-26(29(43-6)18-28(25)39(5)20-23-12-10-15-38(23)4)36-33-34-19-24(32(42)44-21(2)3)31(37-33)40-16-14-22-11-8-9-13-27(22)40/h7-9,11,13-14,16-19,21,23H,1,10,12,15,20H2,2-6H3,(H,35,41)(H,34,36,37)	QIQBFGLTZKXCOD-UHFFFAOYSA-N	368429	US10227342, Example 61	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797255	402365270							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728145	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1ccc2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-17-26(29(43-6)18-28(25)39(5)20-23-12-10-15-38(23)4)36-33-34-19-24(32(42)44-21(2)3)31(37-33)40-16-14-22-11-8-9-13-27(22)40/h7-9,11,13-14,16-19,21,23H,1,10,12,15,20H2,2-6H3,(H,35,41)(H,34,36,37)	QIQBFGLTZKXCOD-UHFFFAOYSA-N	368429	US10227342, Example 61	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797255	402365270							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728146	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1coc2ccccc12 |r|	InChI=1S/C33H38N6O5/c1-7-30(40)35-25-15-26(29(42-6)16-27(25)39(5)18-21-11-10-14-38(21)4)36-33-34-17-23(32(41)44-20(2)3)31(37-33)24-19-43-28-13-9-8-12-22(24)28/h7-9,12-13,15-17,19-21H,1,10-11,14,18H2,2-6H3,(H,35,40)(H,34,36,37)	AOXUCXXQMFHRSG-UHFFFAOYSA-N	368430	US10227342, Example 62	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797254	402365271							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728147	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1coc2ccccc12 |r|	InChI=1S/C33H38N6O5/c1-7-30(40)35-25-15-26(29(42-6)16-27(25)39(5)18-21-11-10-14-38(21)4)36-33-34-17-23(32(41)44-20(2)3)31(37-33)24-19-43-28-13-9-8-12-22(24)28/h7-9,12-13,15-17,19-21H,1,10-11,14,18H2,2-6H3,(H,35,40)(H,34,36,37)	AOXUCXXQMFHRSG-UHFFFAOYSA-N	368430	US10227342, Example 62	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797254	402365271							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728149	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1coc2ccccc12 |r|	InChI=1S/C33H38N6O5/c1-7-30(40)35-25-15-26(29(42-6)16-27(25)39(5)18-21-11-10-14-38(21)4)36-33-34-17-23(32(41)44-20(2)3)31(37-33)24-19-43-28-13-9-8-12-22(24)28/h7-9,12-13,15-17,19-21H,1,10-11,14,18H2,2-6H3,(H,35,40)(H,34,36,37)	AOXUCXXQMFHRSG-UHFFFAOYSA-N	368430	US10227342, Example 62	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797254	402365271							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728150	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)C[C@H]2CCCN2C)nc1-n1ccc2ccccc12 |r|	InChI=1S/C31H35N7O4/c1-6-28(39)33-23-16-24(27(41-4)17-26(23)37(3)19-21-11-9-14-36(21)2)34-31-32-18-22(30(40)42-5)29(35-31)38-15-13-20-10-7-8-12-25(20)38/h6-8,10,12-13,15-18,21H,1,9,11,14,19H2,2-5H3,(H,33,39)(H,32,34,35)	GTGKKQZWZAXKTI-UHFFFAOYSA-N	368431	US10227342, Example 63	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618499	402365272							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728151	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)C[C@H]2CCCN2C)nc1-n1ccc2ccccc12 |r|	InChI=1S/C31H35N7O4/c1-6-28(39)33-23-16-24(27(41-4)17-26(23)37(3)19-21-11-9-14-36(21)2)34-31-32-18-22(30(40)42-5)29(35-31)38-15-13-20-10-7-8-12-25(20)38/h6-8,10,12-13,15-18,21H,1,9,11,14,19H2,2-5H3,(H,33,39)(H,32,34,35)	GTGKKQZWZAXKTI-UHFFFAOYSA-N	368431	US10227342, Example 63	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618499	402365272							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728153	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)C[C@H]2CCCN2C)nc1-n1ccc2ccccc12 |r|	InChI=1S/C31H35N7O4/c1-6-28(39)33-23-16-24(27(41-4)17-26(23)37(3)19-21-11-9-14-36(21)2)34-31-32-18-22(30(40)42-5)29(35-31)38-15-13-20-10-7-8-12-25(20)38/h6-8,10,12-13,15-18,21H,1,9,11,14,19H2,2-5H3,(H,33,39)(H,32,34,35)	GTGKKQZWZAXKTI-UHFFFAOYSA-N	368431	US10227342, Example 63	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618499	402365272							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728154	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)36-26-15-27(29(43-6)16-28(26)40(5)19-21-11-10-14-39(21)4)37-33-35-18-24(32(42)44-20(2)3)31(38-33)23-17-34-25-13-9-8-12-22(23)25/h7-9,12-13,15-18,20-21,34H,1,10-11,14,19H2,2-6H3,(H,36,41)(H,35,37,38)	DQIRQCGGCGXFTQ-UHFFFAOYSA-N	368432	US10227342, Example 64	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368432&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797253	402365273							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728155	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)36-26-15-27(29(43-6)16-28(26)40(5)19-21-11-10-14-39(21)4)37-33-35-18-24(32(42)44-20(2)3)31(38-33)23-17-34-25-13-9-8-12-22(23)25/h7-9,12-13,15-18,20-21,34H,1,10-11,14,19H2,2-6H3,(H,36,41)(H,35,37,38)	DQIRQCGGCGXFTQ-UHFFFAOYSA-N	368432	US10227342, Example 64	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368432&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797253	402365273							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728157	COc1cc(N(C)C[C@H]2CCCN2C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)36-26-15-27(29(43-6)16-28(26)40(5)19-21-11-10-14-39(21)4)37-33-35-18-24(32(42)44-20(2)3)31(38-33)23-17-34-25-13-9-8-12-22(23)25/h7-9,12-13,15-18,20-21,34H,1,10-11,14,19H2,2-6H3,(H,36,41)(H,35,37,38)	DQIRQCGGCGXFTQ-UHFFFAOYSA-N	368432	US10227342, Example 64	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368432&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			140797253	402365273							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728158	CCOC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)C[C@H]2CCCN2C)nc1-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)19-21-12-11-15-38(21)3)36-33-34-18-23(32(42)44-8-2)31(37-33)24-20-40(5)27-14-10-9-13-22(24)27/h7,9-10,13-14,16-18,20-21H,1,8,11-12,15,19H2,2-6H3,(H,35,41)(H,34,36,37)	FAVOTAKMGYDVGB-UHFFFAOYSA-N	368433	US10227342, Example 65	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618216	402365274							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728159	CCOC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)C[C@H]2CCCN2C)nc1-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)19-21-12-11-15-38(21)3)36-33-34-18-23(32(42)44-8-2)31(37-33)24-20-40(5)27-14-10-9-13-22(24)27/h7,9-10,13-14,16-18,20-21H,1,8,11-12,15,19H2,2-6H3,(H,35,41)(H,34,36,37)	FAVOTAKMGYDVGB-UHFFFAOYSA-N	368433	US10227342, Example 65	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618216	402365274							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728161	CCOC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)C[C@H]2CCCN2C)nc1-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)35-25-16-26(29(43-6)17-28(25)39(4)19-21-12-11-15-38(21)3)36-33-34-18-23(32(42)44-8-2)31(37-33)24-20-40(5)27-14-10-9-13-22(24)27/h7,9-10,13-14,16-18,20-21H,1,8,11-12,15,19H2,2-6H3,(H,35,41)(H,34,36,37)	FAVOTAKMGYDVGB-UHFFFAOYSA-N	368433	US10227342, Example 65	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618216	402365274							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728162	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ncccc12	InChI=1S/C30H36N8O4/c1-8-26(39)34-22-14-23(25(41-7)15-24(22)38(6)13-12-37(4)5)35-30-33-17-21(29(40)42-18(2)3)27(36-30)20-16-32-28-19(20)10-9-11-31-28/h8-11,14-18H,1,12-13H2,2-7H3,(H,31,32)(H,34,39)(H,33,35,36)	HKFPIIZGAHWWEG-UHFFFAOYSA-N	368434	US10227342, Example 66	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368434&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201905	402365275							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728163	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ncccc12	InChI=1S/C30H36N8O4/c1-8-26(39)34-22-14-23(25(41-7)15-24(22)38(6)13-12-37(4)5)35-30-33-17-21(29(40)42-18(2)3)27(36-30)20-16-32-28-19(20)10-9-11-31-28/h8-11,14-18H,1,12-13H2,2-7H3,(H,31,32)(H,34,39)(H,33,35,36)	HKFPIIZGAHWWEG-UHFFFAOYSA-N	368434	US10227342, Example 66	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368434&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201905	402365275							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728166	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1c[nH]c2ncccc12	InChI=1S/C30H36N8O4/c1-8-26(39)34-22-14-23(25(41-7)15-24(22)38(6)13-12-37(4)5)35-30-33-17-21(29(40)42-18(2)3)27(36-30)20-16-32-28-19(20)10-9-11-31-28/h8-11,14-18H,1,12-13H2,2-7H3,(H,31,32)(H,34,39)(H,33,35,36)	HKFPIIZGAHWWEG-UHFFFAOYSA-N	368434	US10227342, Example 66	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368434&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201905	402365275							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728167	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C31H36N6O5/c1-8-28(38)33-24-15-23(26(40-7)16-27(24)41-14-13-36(4)5)34-31-32-17-21(30(39)42-19(2)3)29(35-31)22-18-37(6)25-12-10-9-11-20(22)25/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,38)(H,32,34,35)	HYYYICXETWNNEE-UHFFFAOYSA-N	368435	US10227342, Example 67	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201887	402365276							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728168	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C31H36N6O5/c1-8-28(38)33-24-15-23(26(40-7)16-27(24)41-14-13-36(4)5)34-31-32-17-21(30(39)42-19(2)3)29(35-31)22-18-37(6)25-12-10-9-11-20(22)25/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,38)(H,32,34,35)	HYYYICXETWNNEE-UHFFFAOYSA-N	368435	US10227342, Example 67	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201887	402365276							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728171	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12	InChI=1S/C31H36N6O5/c1-8-28(38)33-24-15-23(26(40-7)16-27(24)41-14-13-36(4)5)34-31-32-17-21(30(39)42-19(2)3)29(35-31)22-18-37(6)25-12-10-9-11-20(22)25/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,38)(H,32,34,35)	HYYYICXETWNNEE-UHFFFAOYSA-N	368435	US10227342, Example 67	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201887	402365276							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728172	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)C#CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H30N6O4/c1-7-27(37)32-23-16-24(26(39-5)15-19(23)11-10-14-35(2)3)33-30-31-17-21(29(38)40-6)28(34-30)22-18-36(4)25-13-9-8-12-20(22)25/h7-9,12-13,15-18H,1,14H2,2-6H3,(H,32,37)(H,31,33,34)	XHKCRROMSORZEO-UHFFFAOYSA-N	368436	US10227342, Example 68	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618185	402365277							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728173	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)C#CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H30N6O4/c1-7-27(37)32-23-16-24(26(39-5)15-19(23)11-10-14-35(2)3)33-30-31-17-21(29(38)40-6)28(34-30)22-18-36(4)25-13-9-8-12-20(22)25/h7-9,12-13,15-18H,1,14H2,2-6H3,(H,32,37)(H,31,33,34)	XHKCRROMSORZEO-UHFFFAOYSA-N	368436	US10227342, Example 68	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618185	402365277							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728175	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)C#CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H30N6O4/c1-7-27(37)32-23-16-24(26(39-5)15-19(23)11-10-14-35(2)3)33-30-31-17-21(29(38)40-6)28(34-30)22-18-36(4)25-13-9-8-12-20(22)25/h7-9,12-13,15-18H,1,14H2,2-6H3,(H,32,37)(H,31,33,34)	XHKCRROMSORZEO-UHFFFAOYSA-N	368436	US10227342, Example 68	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618185	402365277							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728176	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(CCCN(C)C)cc2OC)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H34N6O4/c1-7-27(37)32-23-16-24(26(39-5)15-19(23)11-10-14-35(2)3)33-30-31-17-21(29(38)40-6)28(34-30)22-18-36(4)25-13-9-8-12-20(22)25/h7-9,12-13,15-18H,1,10-11,14H2,2-6H3,(H,32,37)(H,31,33,34)	JGPUKTUOHSIAMT-UHFFFAOYSA-N	368437	US10227342, Example 69	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618427	402365278							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728177	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(CCCN(C)C)cc2OC)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H34N6O4/c1-7-27(37)32-23-16-24(26(39-5)15-19(23)11-10-14-35(2)3)33-30-31-17-21(29(38)40-6)28(34-30)22-18-36(4)25-13-9-8-12-20(22)25/h7-9,12-13,15-18H,1,10-11,14H2,2-6H3,(H,32,37)(H,31,33,34)	JGPUKTUOHSIAMT-UHFFFAOYSA-N	368437	US10227342, Example 69	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618427	402365278							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728179	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(CCCN(C)C)cc2OC)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H34N6O4/c1-7-27(37)32-23-16-24(26(39-5)15-19(23)11-10-14-35(2)3)33-30-31-17-21(29(38)40-6)28(34-30)22-18-36(4)25-13-9-8-12-20(22)25/h7-9,12-13,15-18H,1,10-11,14H2,2-6H3,(H,32,37)(H,31,33,34)	JGPUKTUOHSIAMT-UHFFFAOYSA-N	368437	US10227342, Example 69	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618427	402365278							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728180	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(CC(N)=O)c2ccccc12	InChI=1S/C29H34N8O3/c1-6-28(39)32-22-15-23(26(40-5)16-25(22)36(4)14-13-35(2)3)34-29-31-12-11-21(33-29)20-17-37(18-27(30)38)24-10-8-7-9-19(20)24/h6-12,15-17H,1,13-14,18H2,2-5H3,(H2,30,38)(H,32,39)(H,31,33,34)	FTMXBCTZRVMAGG-UHFFFAOYSA-N	368438	US10227342, Example 70	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618384	402365279							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728183	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(CC(N)=O)c2ccccc12	InChI=1S/C29H34N8O3/c1-6-28(39)32-22-15-23(26(40-5)16-25(22)36(4)14-13-35(2)3)34-29-31-12-11-21(33-29)20-17-37(18-27(30)38)24-10-8-7-9-19(20)24/h6-12,15-17H,1,13-14,18H2,2-5H3,(H2,30,38)(H,32,39)(H,31,33,34)	FTMXBCTZRVMAGG-UHFFFAOYSA-N	368438	US10227342, Example 70	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618384	402365279							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728184	CCc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(CC(N)=O)c2ccccc12	InChI=1S/C31H38N8O3/c1-7-20-17-33-31(36-30(20)22-18-39(19-28(32)40)25-12-10-9-11-21(22)25)35-24-15-23(34-29(41)8-2)26(16-27(24)42-6)38(5)14-13-37(3)4/h8-12,15-18H,2,7,13-14,19H2,1,3-6H3,(H2,32,40)(H,34,41)(H,33,35,36)	PYQPMCJCYCGFME-UHFFFAOYSA-N	368440	US10227342, Example 71	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368440&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618556	402365281							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728187	CCc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(CC(N)=O)c2ccccc12	InChI=1S/C31H38N8O3/c1-7-20-17-33-31(36-30(20)22-18-39(19-28(32)40)25-12-10-9-11-21(22)25)35-24-15-23(34-29(41)8-2)26(16-27(24)42-6)38(5)14-13-37(3)4/h8-12,15-18H,2,7,13-14,19H2,1,3-6H3,(H2,32,40)(H,34,41)(H,33,35,36)	PYQPMCJCYCGFME-UHFFFAOYSA-N	368440	US10227342, Example 71	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368440&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618556	402365281							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728188	CCc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(CC(=O)NC)c2ccccc12	InChI=1S/C32H40N8O3/c1-8-21-18-34-32(37-31(21)23-19-40(20-30(42)33-3)26-13-11-10-12-22(23)26)36-25-16-24(35-29(41)9-2)27(17-28(25)43-7)39(6)15-14-38(4)5/h9-13,16-19H,2,8,14-15,20H2,1,3-7H3,(H,33,42)(H,35,41)(H,34,36,37)	LAUSBFAXWVERLC-UHFFFAOYSA-N	368441	US10227342, Example 72	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618228	402365282							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728191	CCc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(CC(=O)NC)c2ccccc12	InChI=1S/C32H40N8O3/c1-8-21-18-34-32(37-31(21)23-19-40(20-30(42)33-3)26-13-11-10-12-22(23)26)36-25-16-24(35-29(41)9-2)27(17-28(25)43-7)39(6)15-14-38(4)5/h9-13,16-19H,2,8,14-15,20H2,1,3-7H3,(H,33,42)(H,35,41)(H,34,36,37)	LAUSBFAXWVERLC-UHFFFAOYSA-N	368441	US10227342, Example 72	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618228	402365282							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728192	COc1cc(N(C)C[C@@H]2CCCN2)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)36-25-15-26(29(43-6)16-28(25)39(4)18-21-11-10-14-34-21)37-33-35-17-23(32(42)44-20(2)3)31(38-33)24-19-40(5)27-13-9-8-12-22(24)27/h7-9,12-13,15-17,19-21,34H,1,10-11,14,18H2,2-6H3,(H,36,41)(H,35,37,38)	GLXLQRWVGCBNQP-UHFFFAOYSA-N	368442	US10227342, Example 73	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368442&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			145713754	402365283							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728193	COc1cc(N(C)C[C@@H]2CCCN2)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)36-25-15-26(29(43-6)16-28(25)39(4)18-21-11-10-14-34-21)37-33-35-17-23(32(42)44-20(2)3)31(38-33)24-19-40(5)27-13-9-8-12-22(24)27/h7-9,12-13,15-17,19-21,34H,1,10-11,14,18H2,2-6H3,(H,36,41)(H,35,37,38)	GLXLQRWVGCBNQP-UHFFFAOYSA-N	368442	US10227342, Example 73	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368442&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			145713754	402365283							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728196	COc1cc(N(C)C[C@@H]2CCCN2)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12 |r|	InChI=1S/C33H39N7O4/c1-7-30(41)36-25-15-26(29(43-6)16-28(25)39(4)18-21-11-10-14-34-21)37-33-35-17-23(32(42)44-20(2)3)31(38-33)24-19-40(5)27-13-9-8-12-22(24)27/h7-9,12-13,15-17,19-21,34H,1,10-11,14,18H2,2-6H3,(H,36,41)(H,35,37,38)	GLXLQRWVGCBNQP-UHFFFAOYSA-N	368442	US10227342, Example 73	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368442&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			145713754	402365283							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728197	CNCCN(C)c1cc(OC)c(Nc2ncc(C(=O)OC(C)C)c(n2)-c2cn(C)c3ncccc23)cc1NC(=O)C=C	InChI=1S/C30H36N8O4/c1-8-26(39)34-22-14-23(25(41-7)15-24(22)37(5)13-12-31-4)35-30-33-16-20(29(40)42-18(2)3)27(36-30)21-17-38(6)28-19(21)10-9-11-32-28/h8-11,14-18,31H,1,12-13H2,2-7H3,(H,34,39)(H,33,35,36)	FABVPXAVMGBCGS-UHFFFAOYSA-N	368443	US10227342, Example 74	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201840	402365284							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728198	CNCCN(C)c1cc(OC)c(Nc2ncc(C(=O)OC(C)C)c(n2)-c2cn(C)c3ncccc23)cc1NC(=O)C=C	InChI=1S/C30H36N8O4/c1-8-26(39)34-22-14-23(25(41-7)15-24(22)37(5)13-12-31-4)35-30-33-16-20(29(40)42-18(2)3)27(36-30)21-17-38(6)28-19(21)10-9-11-32-28/h8-11,14-18,31H,1,12-13H2,2-7H3,(H,34,39)(H,33,35,36)	FABVPXAVMGBCGS-UHFFFAOYSA-N	368443	US10227342, Example 74	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201840	402365284							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728201	CNCCN(C)c1cc(OC)c(Nc2ncc(C(=O)OC(C)C)c(n2)-c2cn(C)c3ncccc23)cc1NC(=O)C=C	InChI=1S/C30H36N8O4/c1-8-26(39)34-22-14-23(25(41-7)15-24(22)37(5)13-12-31-4)35-30-33-16-20(29(40)42-18(2)3)27(36-30)21-17-38(6)28-19(21)10-9-11-32-28/h8-11,14-18,31H,1,12-13H2,2-7H3,(H,34,39)(H,33,35,36)	FABVPXAVMGBCGS-UHFFFAOYSA-N	368443	US10227342, Example 74	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201840	402365284							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728202	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(F)cc2OC)nc1-c1cn(N(C)C)c2ccccc12	InChI=1S/C26H25FN6O4/c1-6-23(34)29-19-12-20(22(36-4)11-18(19)27)30-26-28-13-16(25(35)37-5)24(31-26)17-14-33(32(2)3)21-10-8-7-9-15(17)21/h6-14H,1H2,2-5H3,(H,29,34)(H,28,30,31)	KUYOTTRSZSLXDS-UHFFFAOYSA-N	368444	US10227342, Example 75	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607855	402365285							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728203	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(F)cc2OC)nc1-c1cn(N(C)C)c2ccccc12	InChI=1S/C26H25FN6O4/c1-6-23(34)29-19-12-20(22(36-4)11-18(19)27)30-26-28-13-16(25(35)37-5)24(31-26)17-14-33(32(2)3)21-10-8-7-9-15(17)21/h6-14H,1H2,2-5H3,(H,29,34)(H,28,30,31)	KUYOTTRSZSLXDS-UHFFFAOYSA-N	368444	US10227342, Example 75	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607855	402365285							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728205	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(F)cc2OC)nc1-c1cn(N(C)C)c2ccccc12	InChI=1S/C26H25FN6O4/c1-6-23(34)29-19-12-20(22(36-4)11-18(19)27)30-26-28-13-16(25(35)37-5)24(31-26)17-14-33(32(2)3)21-10-8-7-9-15(17)21/h6-14H,1H2,2-5H3,(H,29,34)(H,28,30,31)	KUYOTTRSZSLXDS-UHFFFAOYSA-N	368444	US10227342, Example 75	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607855	402365285							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728206	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(N(C)C)c2ccccc12	InChI=1S/C31H38N8O4/c1-9-28(40)33-23-16-24(27(42-7)17-26(23)38(6)15-14-36(2)3)34-31-32-18-21(30(41)43-8)29(35-31)22-19-39(37(4)5)25-13-11-10-12-20(22)25/h9-13,16-19H,1,14-15H2,2-8H3,(H,33,40)(H,32,34,35)	LTEOYGMBKQGASV-UHFFFAOYSA-N	368445	US10227342, Example 76	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618570	402365286							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728207	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(N(C)C)c2ccccc12	InChI=1S/C31H38N8O4/c1-9-28(40)33-23-16-24(27(42-7)17-26(23)38(6)15-14-36(2)3)34-31-32-18-21(30(41)43-8)29(35-31)22-19-39(37(4)5)25-13-11-10-12-20(22)25/h9-13,16-19H,1,14-15H2,2-8H3,(H,33,40)(H,32,34,35)	LTEOYGMBKQGASV-UHFFFAOYSA-N	368445	US10227342, Example 76	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618570	402365286							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728209	COC(=O)c1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(N(C)C)c2ccccc12	InChI=1S/C31H38N8O4/c1-9-28(40)33-23-16-24(27(42-7)17-26(23)38(6)15-14-36(2)3)34-31-32-18-21(30(41)43-8)29(35-31)22-19-39(37(4)5)25-13-11-10-12-20(22)25/h9-13,16-19H,1,14-15H2,2-8H3,(H,33,40)(H,32,34,35)	LTEOYGMBKQGASV-UHFFFAOYSA-N	368445	US10227342, Example 76	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118618570	402365286							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728210	CCn1cc(-c2nc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)ncc2C(=O)OC(C)C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-30(41)35-25-17-26(29(43-8)18-28(25)39(7)16-15-38(5)6)36-33-34-19-23(32(42)44-21(3)4)31(37-33)24-20-40(10-2)27-14-12-11-13-22(24)27/h9,11-14,17-21H,1,10,15-16H2,2-8H3,(H,35,41)(H,34,36,37)	FDTGYJGRULJHQZ-UHFFFAOYSA-N	368446	US10227342, Example 77	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201873	402365287							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728211	CCn1cc(-c2nc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)ncc2C(=O)OC(C)C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-30(41)35-25-17-26(29(43-8)18-28(25)39(7)16-15-38(5)6)36-33-34-19-23(32(42)44-21(3)4)31(37-33)24-20-40(10-2)27-14-12-11-13-22(24)27/h9,11-14,17-21H,1,10,15-16H2,2-8H3,(H,35,41)(H,34,36,37)	FDTGYJGRULJHQZ-UHFFFAOYSA-N	368446	US10227342, Example 77	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201873	402365287							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728214	CCn1cc(-c2nc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)ncc2C(=O)OC(C)C)c2ccccc12	InChI=1S/C33H41N7O4/c1-9-30(41)35-25-17-26(29(43-8)18-28(25)39(7)16-15-38(5)6)36-33-34-19-23(32(42)44-21(3)4)31(37-33)24-20-40(10-2)27-14-12-11-13-22(24)27/h9,11-14,17-21H,1,10,15-16H2,2-8H3,(H,35,41)(H,34,36,37)	FDTGYJGRULJHQZ-UHFFFAOYSA-N	368446	US10227342, Example 77	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201873	402365287							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728215	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C(C)=O)c2ccccc12	InChI=1S/C33H39N7O5/c1-9-30(42)35-25-16-26(29(44-8)17-28(25)39(7)15-14-38(5)6)36-33-34-18-23(32(43)45-20(2)3)31(37-33)24-19-40(21(4)41)27-13-11-10-12-22(24)27/h9-13,16-20H,1,14-15H2,2-8H3,(H,35,42)(H,34,36,37)	HHLHKPYGNVLWFW-UHFFFAOYSA-N	368447	US10227342, Example 78	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201897	402365288							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728216	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C(C)=O)c2ccccc12	InChI=1S/C33H39N7O5/c1-9-30(42)35-25-16-26(29(44-8)17-28(25)39(7)15-14-38(5)6)36-33-34-18-23(32(43)45-20(2)3)31(37-33)24-19-40(21(4)41)27-13-11-10-12-22(24)27/h9-13,16-20H,1,14-15H2,2-8H3,(H,35,42)(H,34,36,37)	HHLHKPYGNVLWFW-UHFFFAOYSA-N	368447	US10227342, Example 78	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201897	402365288							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728218	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C(C)=O)c2ccccc12	InChI=1S/C33H39N7O5/c1-9-30(42)35-25-16-26(29(44-8)17-28(25)39(7)15-14-38(5)6)36-33-34-18-23(32(43)45-20(2)3)31(37-33)24-19-40(21(4)41)27-13-11-10-12-22(24)27/h9-13,16-20H,1,14-15H2,2-8H3,(H,35,42)(H,34,36,37)	HHLHKPYGNVLWFW-UHFFFAOYSA-N	368447	US10227342, Example 78	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201897	402365288							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728219	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C2CC2)c2ccccc12	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-17-27(30(44-7)18-29(26)40(6)16-15-39(4)5)37-34-35-19-24(33(43)45-21(2)3)32(38-34)25-20-41(22-13-14-22)28-12-10-9-11-23(25)28/h8-12,17-22H,1,13-16H2,2-7H3,(H,36,42)(H,35,37,38)	CJYGTSPFGMKIEK-UHFFFAOYSA-N	368448	US10227342, Example 79	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201885	402365289							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728220	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C2CC2)c2ccccc12	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-17-27(30(44-7)18-29(26)40(6)16-15-39(4)5)37-34-35-19-24(33(43)45-21(2)3)32(38-34)25-20-41(22-13-14-22)28-12-10-9-11-23(25)28/h8-12,17-22H,1,13-16H2,2-7H3,(H,36,42)(H,35,37,38)	CJYGTSPFGMKIEK-UHFFFAOYSA-N	368448	US10227342, Example 79	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201885	402365289							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728222	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C2CC2)c2ccccc12	InChI=1S/C34H41N7O4/c1-8-31(42)36-26-17-27(30(44-7)18-29(26)40(6)16-15-39(4)5)37-34-35-19-24(33(43)45-21(2)3)32(38-34)25-20-41(22-13-14-22)28-12-10-9-11-23(25)28/h8-12,17-22H,1,13-16H2,2-7H3,(H,36,42)(H,35,37,38)	CJYGTSPFGMKIEK-UHFFFAOYSA-N	368448	US10227342, Example 79	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368448&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201885	402365289							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728223	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cccc(C)c12	InChI=1S/C29H35N7O2/c1-8-27(37)31-22-16-23(26(38-7)17-25(22)35(5)15-14-34(3)4)33-29-30-13-12-21(32-29)20-18-36(6)24-11-9-10-19(2)28(20)24/h8-13,16-18H,1,14-15H2,2-7H3,(H,31,37)(H,30,32,33)	VLUMQFRSXBHHSB-UHFFFAOYSA-N	368449	US10227342, Example 80	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137437030	402365290							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728224	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cccc(C)c12	InChI=1S/C29H35N7O2/c1-8-27(37)31-22-16-23(26(38-7)17-25(22)35(5)15-14-34(3)4)33-29-30-13-12-21(32-29)20-18-36(6)24-11-9-10-19(2)28(20)24/h8-13,16-18H,1,14-15H2,2-7H3,(H,31,37)(H,30,32,33)	VLUMQFRSXBHHSB-UHFFFAOYSA-N	368449	US10227342, Example 80	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137437030	402365290							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728226	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cccc(C)c12	InChI=1S/C29H35N7O2/c1-8-27(37)31-22-16-23(26(38-7)17-25(22)35(5)15-14-34(3)4)33-29-30-13-12-21(32-29)20-18-36(6)24-11-9-10-19(2)28(20)24/h8-13,16-18H,1,14-15H2,2-7H3,(H,31,37)(H,30,32,33)	VLUMQFRSXBHHSB-UHFFFAOYSA-N	368449	US10227342, Example 80	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368449&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137437030	402365290							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728227	COC(=O)c1ccc2n(C)cc(-c3ccnc(Nc4cc(NC(=O)C=C)c(cc4OC)N(C)CCN(C)C)n3)c2c1	InChI=1S/C30H35N7O4/c1-8-28(38)32-23-16-24(27(40-6)17-26(23)36(4)14-13-35(2)3)34-30-31-12-11-22(33-30)21-18-37(5)25-10-9-19(15-20(21)25)29(39)41-7/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	SOZQQMFJCXIIKY-UHFFFAOYSA-N	368450	US10227342, Example 81	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368450&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607866	402365291							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728228	COC(=O)c1ccc2n(C)cc(-c3ccnc(Nc4cc(NC(=O)C=C)c(cc4OC)N(C)CCN(C)C)n3)c2c1	InChI=1S/C30H35N7O4/c1-8-28(38)32-23-16-24(27(40-6)17-26(23)36(4)14-13-35(2)3)34-30-31-12-11-22(33-30)21-18-37(5)25-10-9-19(15-20(21)25)29(39)41-7/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	SOZQQMFJCXIIKY-UHFFFAOYSA-N	368450	US10227342, Example 81	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368450&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607866	402365291							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728230	COC(=O)c1ccc2n(C)cc(-c3ccnc(Nc4cc(NC(=O)C=C)c(cc4OC)N(C)CCN(C)C)n3)c2c1	InChI=1S/C30H35N7O4/c1-8-28(38)32-23-16-24(27(40-6)17-26(23)36(4)14-13-35(2)3)34-30-31-12-11-22(33-30)21-18-37(5)25-10-9-19(15-20(21)25)29(39)41-7/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	SOZQQMFJCXIIKY-UHFFFAOYSA-N	368450	US10227342, Example 81	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368450&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607866	402365291							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728231	COC(=O)c1ccc2c(cn(C)c2c1)-c1ccnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)n1	InChI=1S/C30H35N7O4/c1-8-28(38)32-23-16-24(27(40-6)17-26(23)36(4)14-13-35(2)3)34-30-31-12-11-22(33-30)21-18-37(5)25-15-19(29(39)41-7)9-10-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	LDUDZUCPQNPFAY-UHFFFAOYSA-N	368452	US10227342, Example 82	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368452&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607844	402365293							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728232	COC(=O)c1ccc2c(cn(C)c2c1)-c1ccnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)n1	InChI=1S/C30H35N7O4/c1-8-28(38)32-23-16-24(27(40-6)17-26(23)36(4)14-13-35(2)3)34-30-31-12-11-22(33-30)21-18-37(5)25-15-19(29(39)41-7)9-10-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	LDUDZUCPQNPFAY-UHFFFAOYSA-N	368452	US10227342, Example 82	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368452&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607844	402365293							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728234	COC(=O)c1ccc2c(cn(C)c2c1)-c1ccnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)n1	InChI=1S/C30H35N7O4/c1-8-28(38)32-23-16-24(27(40-6)17-26(23)36(4)14-13-35(2)3)34-30-31-12-11-22(33-30)21-18-37(5)25-15-19(29(39)41-7)9-10-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,32,38)(H,31,33,34)	LDUDZUCPQNPFAY-UHFFFAOYSA-N	368452	US10227342, Example 82	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368452&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607844	402365293							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728235	COC(=O)c1cccc2c(cn(C)c12)-c1ccnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)n1	InChI=1S/C30H35N7O4/c1-8-27(38)32-23-16-24(26(40-6)17-25(23)36(4)15-14-35(2)3)34-30-31-13-12-22(33-30)21-18-37(5)28-19(21)10-9-11-20(28)29(39)41-7/h8-13,16-18H,1,14-15H2,2-7H3,(H,32,38)(H,31,33,34)	LJLRNWREQIYWCN-UHFFFAOYSA-N	368453	US10227342, Example 83	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368453&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130218131	402365294							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728238	COC(=O)c1cccc2c(cn(C)c12)-c1ccnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)n1	InChI=1S/C30H35N7O4/c1-8-27(38)32-23-16-24(26(40-6)17-25(23)36(4)15-14-35(2)3)34-30-31-13-12-22(33-30)21-18-37(5)28-19(21)10-9-11-20(28)29(39)41-7/h8-13,16-18H,1,14-15H2,2-7H3,(H,32,38)(H,31,33,34)	LJLRNWREQIYWCN-UHFFFAOYSA-N	368453	US10227342, Example 83	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368453&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130218131	402365294							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728239	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cc(ccc12)C(=O)OC(C)C	InChI=1S/C32H39N7O4/c1-9-30(40)34-25-17-26(29(42-8)18-28(25)38(6)15-14-37(4)5)36-32-33-13-12-24(35-32)23-19-39(7)27-16-21(10-11-22(23)27)31(41)43-20(2)3/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	KBZYPUVCUIOGRZ-UHFFFAOYSA-N	368454	US10227342, Example 84	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368454&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607837	402365295							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728242	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cc(ccc12)C(=O)OC(C)C	InChI=1S/C32H39N7O4/c1-9-30(40)34-25-17-26(29(42-8)18-28(25)38(6)15-14-37(4)5)36-32-33-13-12-24(35-32)23-19-39(7)27-16-21(10-11-22(23)27)31(41)43-20(2)3/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	KBZYPUVCUIOGRZ-UHFFFAOYSA-N	368454	US10227342, Example 84	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368454&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607837	402365295							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728243	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2c(cccc12)C(=O)OC(C)C	InChI=1S/C32H39N7O4/c1-9-29(40)34-25-17-26(28(42-8)18-27(25)38(6)16-15-37(4)5)36-32-33-14-13-24(35-32)23-19-39(7)30-21(23)11-10-12-22(30)31(41)43-20(2)3/h9-14,17-20H,1,15-16H2,2-8H3,(H,34,40)(H,33,35,36)	FJVWMLNMRVORRW-UHFFFAOYSA-N	368455	US10227342, Example 85	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368455&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607876	402365296							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728246	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2c(cccc12)C(=O)OC(C)C	InChI=1S/C32H39N7O4/c1-9-29(40)34-25-17-26(28(42-8)18-27(25)38(6)16-15-37(4)5)36-32-33-14-13-24(35-32)23-19-39(7)30-21(23)11-10-12-22(30)31(41)43-20(2)3/h9-14,17-20H,1,15-16H2,2-8H3,(H,34,40)(H,33,35,36)	FJVWMLNMRVORRW-UHFFFAOYSA-N	368455	US10227342, Example 85	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368455&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607876	402365296							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728247	COC(=O)c1c(-c2ccnc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)n2)c2ccccc2n1C	InChI=1S/C30H35N7O4/c1-8-26(38)32-21-17-22(25(40-6)18-24(21)36(4)16-15-35(2)3)34-30-31-14-13-20(33-30)27-19-11-9-10-12-23(19)37(5)28(27)29(39)41-7/h8-14,17-18H,1,15-16H2,2-7H3,(H,32,38)(H,31,33,34)	VSNJOOJLUSUZRB-UHFFFAOYSA-N	368457	US10227342, Example 86	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368457&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607877	402365298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728250	COC(=O)c1c(-c2ccnc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)n2)c2ccccc2n1C	InChI=1S/C30H35N7O4/c1-8-26(38)32-21-17-22(25(40-6)18-24(21)36(4)16-15-35(2)3)34-30-31-14-13-20(33-30)27-19-11-9-10-12-23(19)37(5)28(27)29(39)41-7/h8-14,17-18H,1,15-16H2,2-7H3,(H,32,38)(H,31,33,34)	VSNJOOJLUSUZRB-UHFFFAOYSA-N	368457	US10227342, Example 86	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368457&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607877	402365298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728251	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C(=O)OC(C)C)n(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-28(40)34-23-18-24(27(42-8)19-26(23)38(6)17-16-37(4)5)36-32-33-15-14-22(35-32)29-21-12-10-11-13-25(21)39(7)30(29)31(41)43-20(2)3/h9-15,18-20H,1,16-17H2,2-8H3,(H,34,40)(H,33,35,36)	KYKUDMMTAXZQCK-UHFFFAOYSA-N	368458	US10227342, Example 87	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368458&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607874	402365299							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728254	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C(=O)OC(C)C)n(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-28(40)34-23-18-24(27(42-8)19-26(23)38(6)17-16-37(4)5)36-32-33-15-14-22(35-32)29-21-12-10-11-13-25(21)39(7)30(29)31(41)43-20(2)3/h9-15,18-20H,1,16-17H2,2-8H3,(H,34,40)(H,33,35,36)	KYKUDMMTAXZQCK-UHFFFAOYSA-N	368458	US10227342, Example 87	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368458&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607874	402365299							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728255	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C#N)n(C)c2ccccc12	InChI=1S/C29H32N8O2/c1-7-27(38)32-21-16-22(26(39-6)17-24(21)36(4)15-14-35(2)3)34-29-31-13-12-20(33-29)28-19-10-8-9-11-23(19)37(5)25(28)18-30/h7-13,16-17H,1,14-15H2,2-6H3,(H,32,38)(H,31,33,34)	LOZJHXOGUOTPOV-UHFFFAOYSA-N	368459	US10227342, Example 88	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368459&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607859	402365300							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728258	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C#N)n(C)c2ccccc12	InChI=1S/C29H32N8O2/c1-7-27(38)32-21-16-22(26(39-6)17-24(21)36(4)15-14-35(2)3)34-29-31-13-12-20(33-29)28-19-10-8-9-11-23(19)37(5)25(28)18-30/h7-13,16-17H,1,14-15H2,2-6H3,(H,32,38)(H,31,33,34)	LOZJHXOGUOTPOV-UHFFFAOYSA-N	368459	US10227342, Example 88	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368459&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607859	402365300							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728259	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cc(ccc12)C#N	InChI=1S/C29H32N8O2/c1-7-28(38)32-23-15-24(27(39-6)16-26(23)36(4)13-12-35(2)3)34-29-31-11-10-22(33-29)21-18-37(5)25-14-19(17-30)8-9-20(21)25/h7-11,14-16,18H,1,12-13H2,2-6H3,(H,32,38)(H,31,33,34)	OORYXVCGDWMKPP-UHFFFAOYSA-N	368460	US10227342, Example 89	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368460&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607848	402365301							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728262	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cc(ccc12)C#N	InChI=1S/C29H32N8O2/c1-7-28(38)32-23-15-24(27(39-6)16-26(23)36(4)13-12-35(2)3)34-29-31-11-10-22(33-29)21-18-37(5)25-14-19(17-30)8-9-20(21)25/h7-11,14-16,18H,1,12-13H2,2-6H3,(H,32,38)(H,31,33,34)	OORYXVCGDWMKPP-UHFFFAOYSA-N	368460	US10227342, Example 89	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368460&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607848	402365301							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728263	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C(N)=O)n(C)c2ccccc12	InChI=1S/C29H34N8O3/c1-7-25(38)32-20-16-21(24(40-6)17-23(20)36(4)15-14-35(2)3)34-29-31-13-12-19(33-29)26-18-10-8-9-11-22(18)37(5)27(26)28(30)39/h7-13,16-17H,1,14-15H2,2-6H3,(H2,30,39)(H,32,38)(H,31,33,34)	YZWMBQDHHQCRAP-UHFFFAOYSA-N	368462	US10227342, Example 90	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368462&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201868	402365303							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728266	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C(N)=O)n(C)c2ccccc12	InChI=1S/C29H34N8O3/c1-7-25(38)32-20-16-21(24(40-6)17-23(20)36(4)15-14-35(2)3)34-29-31-13-12-19(33-29)26-18-10-8-9-11-22(18)37(5)27(26)28(30)39/h7-13,16-17H,1,14-15H2,2-6H3,(H2,30,39)(H,32,38)(H,31,33,34)	YZWMBQDHHQCRAP-UHFFFAOYSA-N	368462	US10227342, Example 90	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368462&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201868	402365303							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728267	CNC(=O)c1c(-c2ccnc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)n2)c2ccccc2n1C	InChI=1S/C30H36N8O3/c1-8-26(39)33-21-17-22(25(41-7)18-24(21)37(5)16-15-36(3)4)35-30-32-14-13-20(34-30)27-19-11-9-10-12-23(19)38(6)28(27)29(40)31-2/h8-14,17-18H,1,15-16H2,2-7H3,(H,31,40)(H,33,39)(H,32,34,35)	KPZASAOQJPELDP-UHFFFAOYSA-N	368463	US10227342, Example 91	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368463&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607820	402365304							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728270	CNC(=O)c1c(-c2ccnc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)n2)c2ccccc2n1C	InChI=1S/C30H36N8O3/c1-8-26(39)33-21-17-22(25(41-7)18-24(21)37(5)16-15-36(3)4)35-30-32-14-13-20(34-30)27-19-11-9-10-12-23(19)38(6)28(27)29(40)31-2/h8-14,17-18H,1,15-16H2,2-7H3,(H,31,40)(H,33,39)(H,32,34,35)	KPZASAOQJPELDP-UHFFFAOYSA-N	368463	US10227342, Example 91	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368463&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607820	402365304							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728271	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C(=O)N(C)C)n(C)c2ccccc12	InChI=1S/C31H38N8O3/c1-9-27(40)33-22-18-23(26(42-8)19-25(22)38(6)17-16-36(2)3)35-31-32-15-14-21(34-31)28-20-12-10-11-13-24(20)39(7)29(28)30(41)37(4)5/h9-15,18-19H,1,16-17H2,2-8H3,(H,33,40)(H,32,34,35)	YDLLORHPSSVDHG-UHFFFAOYSA-N	368464	US10227342, Example 92	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368464&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607843	402365305							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728274	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c(C(=O)N(C)C)n(C)c2ccccc12	InChI=1S/C31H38N8O3/c1-9-27(40)33-22-18-23(26(42-8)19-25(22)38(6)17-16-36(2)3)35-31-32-15-14-21(34-31)28-20-12-10-11-13-24(20)39(7)29(28)30(41)37(4)5/h9-15,18-19H,1,16-17H2,2-8H3,(H,33,40)(H,32,34,35)	YDLLORHPSSVDHG-UHFFFAOYSA-N	368464	US10227342, Example 92	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368464&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607843	402365305							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728275	COCCNC(=O)c1c(-c2ccnc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)n2)c2ccccc2n1C	InChI=1S/C32H40N8O4/c1-8-28(41)35-23-19-24(27(44-7)20-26(23)39(4)17-16-38(2)3)37-32-34-14-13-22(36-32)29-21-11-9-10-12-25(21)40(5)30(29)31(42)33-15-18-43-6/h8-14,19-20H,1,15-18H2,2-7H3,(H,33,42)(H,35,41)(H,34,36,37)	ZHXZOLMZOLHODX-UHFFFAOYSA-N	368465	US10227342, Example 93	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368465&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607828	402365306							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728278	COCCNC(=O)c1c(-c2ccnc(Nc3cc(NC(=O)C=C)c(cc3OC)N(C)CCN(C)C)n2)c2ccccc2n1C	InChI=1S/C32H40N8O4/c1-8-28(41)35-23-19-24(27(44-7)20-26(23)39(4)17-16-38(2)3)37-32-34-14-13-22(36-32)29-21-11-9-10-12-25(21)40(5)30(29)31(42)33-15-18-43-6/h8-14,19-20H,1,15-18H2,2-7H3,(H,33,42)(H,35,41)(H,34,36,37)	ZHXZOLMZOLHODX-UHFFFAOYSA-N	368465	US10227342, Example 93	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368465&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118607828	402365306							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728279	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cnc2ccccn12	InChI=1S/C30H36N8O4/c1-8-27(39)33-21-15-22(25(41-7)16-23(21)37(6)14-13-36(4)5)34-30-32-17-20(29(40)42-19(2)3)28(35-30)24-18-31-26-11-9-10-12-38(24)26/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,39)(H,32,34,35)	RSPSMBVIDXEVMI-UHFFFAOYSA-N	368466	US10227342, Example 94	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368466&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201831	402365307							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728280	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cnc2ccccn12	InChI=1S/C30H36N8O4/c1-8-27(39)33-21-15-22(25(41-7)16-23(21)37(6)14-13-36(4)5)34-30-32-17-20(29(40)42-19(2)3)28(35-30)24-18-31-26-11-9-10-12-38(24)26/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,39)(H,32,34,35)	RSPSMBVIDXEVMI-UHFFFAOYSA-N	368466	US10227342, Example 94	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368466&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201831	402365307							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728282	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cnc2ccccn12	InChI=1S/C30H36N8O4/c1-8-27(39)33-21-15-22(25(41-7)16-23(21)37(6)14-13-36(4)5)34-30-32-17-20(29(40)42-19(2)3)28(35-30)24-18-31-26-11-9-10-12-38(24)26/h8-12,15-19H,1,13-14H2,2-7H3,(H,33,39)(H,32,34,35)	RSPSMBVIDXEVMI-UHFFFAOYSA-N	368466	US10227342, Example 94	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368466&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201831	402365307							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728283	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cc(ccc12)-c1cnn(C)c1	InChI=1S/C32H37N9O2/c1-8-31(42)35-26-16-27(30(43-7)17-29(26)39(4)14-13-38(2)3)37-32-33-12-11-25(36-32)24-20-40(5)28-15-21(9-10-23(24)28)22-18-34-41(6)19-22/h8-12,15-20H,1,13-14H2,2-7H3,(H,35,42)(H,33,36,37)	RKRVABRGLJBGOI-UHFFFAOYSA-N	368467	US10227342, Example 95	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368467&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201834	402365308							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728286	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cc(ccc12)-c1cnn(C)c1	InChI=1S/C32H37N9O2/c1-8-31(42)35-26-16-27(30(43-7)17-29(26)39(4)14-13-38(2)3)37-32-33-12-11-25(36-32)24-20-40(5)28-15-21(9-10-23(24)28)22-18-34-41(6)19-22/h8-12,15-20H,1,13-14H2,2-7H3,(H,35,42)(H,33,36,37)	RKRVABRGLJBGOI-UHFFFAOYSA-N	368467	US10227342, Example 95	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368467&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201834	402365308							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728287	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(c(n1)-c1cn(C)c2ccccc12)P(C)(C)=O	InChI=1S/C30H38N7O3P/c1-9-28(38)32-22-16-23(26(40-6)17-25(22)36(4)15-14-35(2)3)33-30-31-18-27(41(7,8)39)29(34-30)21-19-37(5)24-13-11-10-12-20(21)24/h9-13,16-19H,1,14-15H2,2-8H3,(H,32,38)(H,31,33,34)	VKMKIKBHSVYASJ-UHFFFAOYSA-N	368468	US10227342, Example 96	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368468&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201912	402365309							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728290	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(c(n1)-c1cn(C)c2ccccc12)P(C)(C)=O	InChI=1S/C30H38N7O3P/c1-9-28(38)32-22-16-23(26(40-6)17-25(22)36(4)15-14-35(2)3)33-30-31-18-27(41(7,8)39)29(34-30)21-19-37(5)24-13-11-10-12-20(21)24/h9-13,16-19H,1,14-15H2,2-8H3,(H,32,38)(H,31,33,34)	VKMKIKBHSVYASJ-UHFFFAOYSA-N	368468	US10227342, Example 96	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368468&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201912	402365309							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728291	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1cc(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(7)15-14-37(5)6)35-32-33-18-23(31(41)43-20(2)3)30(36-32)39-19-21(4)22-12-10-11-13-26(22)39/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	DHIMNHBWVAROQJ-UHFFFAOYSA-N	368469	US10227342, Example 97	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368469&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201860	402365310							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728292	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1cc(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(7)15-14-37(5)6)35-32-33-18-23(31(41)43-20(2)3)30(36-32)39-19-21(4)22-12-10-11-13-26(22)39/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	DHIMNHBWVAROQJ-UHFFFAOYSA-N	368469	US10227342, Example 97	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368469&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201860	402365310							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728294	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OC(C)C)c(n1)-n1cc(C)c2ccccc12	InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(7)15-14-37(5)6)35-32-33-18-23(31(41)43-20(2)3)30(36-32)39-19-21(4)22-12-10-11-13-26(22)39/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)	DHIMNHBWVAROQJ-UHFFFAOYSA-N	368469	US10227342, Example 97	Epidermal growth factor receptor	Homo sapiens		 300							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368469&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201860	402365310							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728295	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1nn(C)c2ccccc12	InChI=1S/C27H32N8O2/c1-7-25(36)29-20-16-21(24(37-6)17-23(20)34(4)15-14-33(2)3)31-27-28-13-12-19(30-27)26-18-10-8-9-11-22(18)35(5)32-26/h7-13,16-17H,1,14-15H2,2-6H3,(H,29,36)(H,28,30,31)	NXMMXDPMHWAHPH-UHFFFAOYSA-N	368470	US10227342, Example 98	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368470&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130412638	402365311							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728296	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1nn(C)c2ccccc12	InChI=1S/C27H32N8O2/c1-7-25(36)29-20-16-21(24(37-6)17-23(20)34(4)15-14-33(2)3)31-27-28-13-12-19(30-27)26-18-10-8-9-11-22(18)35(5)32-26/h7-13,16-17H,1,14-15H2,2-6H3,(H,29,36)(H,28,30,31)	NXMMXDPMHWAHPH-UHFFFAOYSA-N	368470	US10227342, Example 98	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368470&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130412638	402365311							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728298	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1nn(C)c2ccccc12	InChI=1S/C27H32N8O2/c1-7-25(36)29-20-16-21(24(37-6)17-23(20)34(4)15-14-33(2)3)31-27-28-13-12-19(30-27)26-18-10-8-9-11-22(18)35(5)32-26/h7-13,16-17H,1,14-15H2,2-6H3,(H,29,36)(H,28,30,31)	NXMMXDPMHWAHPH-UHFFFAOYSA-N	368470	US10227342, Example 98	Epidermal growth factor receptor	Homo sapiens		<100							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368470&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130412638	402365311							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728299	CNC(=O)Nc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H37N9O3/c1-8-27(40)33-21-15-22(26(42-7)16-25(21)38(5)14-13-37(3)4)34-29-32-17-23(35-30(41)31-2)28(36-29)20-18-39(6)24-12-10-9-11-19(20)24/h8-12,15-18H,1,13-14H2,2-7H3,(H,33,40)(H2,31,35,41)(H,32,34,36)	KMHWRNAHDHRFES-UHFFFAOYSA-N	368471	US10227342, Example 99	Epidermal growth factor receptor	Homo sapiens		 750							US Patent		10.7270/Q21Z46Q0		aid1798057	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368471&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201880	402365312							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
728302	CNC(=O)Nc1cnc(Nc2cc(NC(=O)C=C)c(cc2OC)N(C)CCN(C)C)nc1-c1cn(C)c2ccccc12	InChI=1S/C30H37N9O3/c1-8-27(40)33-21-15-22(26(42-7)16-25(21)38(5)14-13-37(3)4)34-29-32-17-23(35-30(41)31-2)28(36-29)20-18-39(6)24-12-10-9-11-19(20)24/h8-12,15-18H,1,13-14H2,2-7H3,(H,33,40)(H2,31,35,41)(H,32,34,36)	KMHWRNAHDHRFES-UHFFFAOYSA-N	368471	US10227342, Example 99	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q21Z46Q0		aid1798059	US10227342	Huang, W; Gong, Y; Li, F; Bencivenga, NE; Dalgarno, DC; Kohlmann, A; Shakespeare, WC; Thomas, RM; Zhu, X; West, A; Youngsaye, W; Zhang, Y; Zhou, T	3/12/2019	12/27/2019	Ariad Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=368471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=368471&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130201880	402365312							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742471	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C1CCSS1	InChI=1S/C22H18ClFN4O2S2/c1-2-30-19-9-17-14(8-18(19)28-22(29)20-5-6-31-32-20)21(12(10-25)11-26-17)27-13-3-4-16(24)15(23)7-13/h3-4,7-9,11,20H,2,5-6H2,1H3,(H,26,27)(H,28,29)	BLRHUONNMVFXTL-UHFFFAOYSA-N	373606	US10246444, Example 33	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373606	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373606&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236445	404342693							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742473	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C(CSC(C)=O)CSC(C)=O	InChI=1S/C33H30ClFN4O5S2/c1-4-43-31-13-28-26(12-29(31)39-33(42)23(17-45-19(2)40)18-46-20(3)41)32(22(14-36)15-37-28)38-25-8-9-30(27(34)11-25)44-16-21-6-5-7-24(35)10-21/h5-13,15,23H,4,16-18H2,1-3H3,(H,37,38)(H,39,42)	BTIIVZRTAZXKHX-UHFFFAOYSA-N	373698	US10246444, Example 34	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373698	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373698&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135251923	404342785					C04334		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742475	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1	InChI=1S/C29H24ClFN4O3S2/c1-2-37-27-11-24-22(10-25(27)35-29(36)19-15-39-40-16-19)28(18(12-32)13-33-24)34-21-6-7-26(23(30)9-21)38-14-17-4-3-5-20(31)8-17/h3-11,13,19H,2,14-16H2,1H3,(H,33,34)(H,35,36)	UTVGMDHMDAFOBZ-UHFFFAOYSA-N	373700	US10246444, Example 36	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373700	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373700&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236457	404342787							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742477	CC1(C)OC[C@H](COc2cc3ncc(C#N)c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3cc2NC(=O)CC2CCSS2)O1 |r|	InChI=1S/C34H32ClFN4O5S2/c1-34(2)44-19-24(45-34)18-43-31-14-28-26(13-29(31)40-32(41)12-25-8-9-46-47-25)33(21(15-37)16-38-28)39-23-6-7-30(27(35)11-23)42-17-20-4-3-5-22(36)10-20/h3-7,10-11,13-14,16,24-25H,8-9,12,17-19H2,1-2H3,(H,38,39)(H,40,41)	CZFLJSHHAMLIOE-UHFFFAOYSA-N	373701	US10246444, Example 84 isomer 2::US10246444, Example 79	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373701&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236717	404342788							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742479	CC1(C)OC[C@H](COc2cc3ncc(C#N)c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3cc2NC(=O)C[C@@H]2CCSS2)O1 |r|	InChI=1S/C34H32ClFN4O5S2/c1-34(2)44-19-24(45-34)18-43-31-14-28-26(13-29(31)40-32(41)12-25-8-9-46-47-25)33(21(15-37)16-38-28)39-23-6-7-30(27(35)11-23)42-17-20-4-3-5-22(36)10-20/h3-7,10-11,13-14,16,24-25H,8-9,12,17-19H2,1-2H3,(H,38,39)(H,40,41)	CZFLJSHHAMLIOE-UHFFFAOYSA-N	373702	US10246444, Example 80 isomer 1	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373702&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236719	404342789							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742481	CC1(C)OC[C@H](COc2cc3ncc(C#N)c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3cc2NC(=O)C[C@H]2CCSS2)O1 |r|	InChI=1S/C34H32ClFN4O5S2/c1-34(2)44-19-24(45-34)18-43-31-14-28-26(13-29(31)40-32(41)12-25-8-9-46-47-25)33(21(15-37)16-38-28)39-23-6-7-30(27(35)11-23)42-17-20-4-3-5-22(36)10-20/h3-7,10-11,13-14,16,24-25H,8-9,12,17-19H2,1-2H3,(H,38,39)(H,40,41)	CZFLJSHHAMLIOE-UHFFFAOYSA-N	373703	US10246444, Example 80 isomer 2	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373703	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373703&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236523	404342790							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742483	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C[C@H]1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373704	US10246444, Example 81	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373704	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373704&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135237001	404342791							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742485	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373705	US10246444, Example 82	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373705&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236450	404342792							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742487	CC1(C)OC[C@@H](COc2cc3ncc(C#N)c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3cc2NC(=O)CC2CCSS2)O1 |r|	InChI=1S/C34H32ClFN4O5S2/c1-34(2)44-19-24(45-34)18-43-31-14-28-26(13-29(31)40-32(41)12-25-8-9-46-47-25)33(21(15-37)16-38-28)39-23-6-7-30(27(35)11-23)42-17-20-4-3-5-22(36)10-20/h3-7,10-11,13-14,16,24-25H,8-9,12,17-19H2,1-2H3,(H,38,39)(H,40,41)	CZFLJSHHAMLIOE-UHFFFAOYSA-N	373706	US10246444, Example 84 isomer 1	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373706	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373706&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236461	404342793							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742489	CC1(C)OC[C@H](COc2cc3ncc(C#N)c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3cc2NC(=O)CC2CCSS2)O1 |r|	InChI=1S/C34H32ClFN4O5S2/c1-34(2)44-19-24(45-34)18-43-31-14-28-26(13-29(31)40-32(41)12-25-8-9-46-47-25)33(21(15-37)16-38-28)39-23-6-7-30(27(35)11-23)42-17-20-4-3-5-22(36)10-20/h3-7,10-11,13-14,16,24-25H,8-9,12,17-19H2,1-2H3,(H,38,39)(H,40,41)	CZFLJSHHAMLIOE-UHFFFAOYSA-N	373701	US10246444, Example 84 isomer 2::US10246444, Example 79	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373701&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236717	404342788							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742491	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C[C@@H]1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373708	US10246444, Example 85	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373708	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373708&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236518	404342794					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742493	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C[C@H]1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373709	US10246444, Example 86	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373709	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373709&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236536	404342795					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742495	CC(=O)SCC(CSC(C)=O)C(=O)Nc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c(cnc2cc1OC[C@H](O)CO)C#N |r|	InChI=1S/C34H32ClFN4O7S2/c1-19(42)48-17-23(18-49-20(2)43)34(45)40-30-10-27-29(11-32(30)47-16-26(44)14-41)38-13-22(12-37)33(27)39-25-6-7-31(28(35)9-25)46-15-21-4-3-5-24(36)8-21/h3-11,13,23,26,41,44H,14-18H2,1-2H3,(H,38,39)(H,40,45)	LHJVOUDPKROHFZ-UHFFFAOYSA-N	373710	US10246444, Example 94	Epidermal growth factor receptor	Homo sapiens			 50						US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373710	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373710&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135251929	404342796					C04334		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742528	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C1CSSC1	InChI=1S/C22H18ClFN4O2S2/c1-2-30-20-7-18-15(6-19(20)28-22(29)13-10-31-32-11-13)21(12(8-25)9-26-18)27-14-3-4-17(24)16(23)5-14/h3-7,9,13H,2,10-11H2,1H3,(H,26,27)(H,28,29)	CNTYSAQKPONNER-UHFFFAOYSA-N	373714	US10246444, Example 31	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373714	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373714&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236483	404342800							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742532	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C(CSC(C)=O)CSC(C)=O	InChI=1S/C33H30ClFN4O5S2/c1-4-43-31-13-28-26(12-29(31)39-33(42)23(17-45-19(2)40)18-46-20(3)41)32(22(14-36)15-37-28)38-25-8-9-30(27(34)11-25)44-16-21-6-5-7-24(35)10-21/h5-13,15,23H,4,16-18H2,1-3H3,(H,37,38)(H,39,42)	BTIIVZRTAZXKHX-UHFFFAOYSA-N	373698	US10246444, Example 34	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373698	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373698&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135251923	404342785					C04334		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742535	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1	InChI=1S/C29H24ClFN4O3S2/c1-2-37-27-11-24-22(10-25(27)35-29(36)19-15-39-40-16-19)28(18(12-32)13-33-24)34-21-6-7-26(23(30)9-21)38-14-17-4-3-5-20(31)8-17/h3-11,13,19H,2,14-16H2,1H3,(H,33,34)(H,35,36)	UTVGMDHMDAFOBZ-UHFFFAOYSA-N	373700	US10246444, Example 36	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373700	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373700&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236457	404342787							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742540	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CCSS1	InChI=1S/C30H26ClFN4O3S2/c1-2-38-28-14-25-23(13-26(28)36-29(37)12-22-8-9-40-41-22)30(19(15-33)16-34-25)35-21-6-7-27(24(31)11-21)39-17-18-4-3-5-20(32)10-18/h3-7,10-11,13-14,16,22H,2,8-9,12,17H2,1H3,(H,34,35)(H,36,37)	QCVAULIYZATFDX-UHFFFAOYSA-N	373711	US10246444, Example 40	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373711	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373711&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236903	404342797							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742543	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCCCC1CCSS1	InChI=1S/C26H26ClFN4O2S2/c1-2-34-24-13-22-19(12-23(24)32-25(33)6-4-3-5-18-9-10-35-36-18)26(16(14-29)15-30-22)31-17-7-8-21(28)20(27)11-17/h7-8,11-13,15,18H,2-6,9-10H2,1H3,(H,30,31)(H,32,33)	ZPSWYIUCRQOXDP-UHFFFAOYSA-N	373717	US10246444, Example 43	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373717&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236756	404342803					C02051		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742547	Cc1ccc(Oc2ccc(Nc3c(cnc4ccc(NC(=O)CC5CCSS5)cc34)C#N)cc2C)cn1	InChI=1S/C28H25N5O2S2/c1-17-11-20(5-8-26(17)35-22-6-3-18(2)30-16-22)33-28-19(14-29)15-31-25-7-4-21(12-24(25)28)32-27(34)13-23-9-10-36-37-23/h3-8,11-12,15-16,23H,9-10,13H2,1-2H3,(H,31,33)(H,32,34)	CQCLAZVGEAFCEC-UHFFFAOYSA-N	373719	US10246444, Example 55	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373719	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373719&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236676	404342805							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742551	CC(=O)SCC(CSC(C)=O)C(=O)Nc1ccc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C31H26ClFN4O4S2/c1-18(38)42-16-22(17-43-19(2)39)31(40)37-24-6-8-28-26(11-24)30(21(13-34)14-35-28)36-25-7-9-29(27(32)12-25)41-15-20-4-3-5-23(33)10-20/h3-12,14,22H,15-17H2,1-2H3,(H,35,36)(H,37,40)	VXCNBTDBUDHSOM-UHFFFAOYSA-N	373721	US10246444, Example 60	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373721	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373721&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135251928	404342807					C04334		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742553	Fc1cccc(COc2ccc(Nc3c(cnc4ccc(NC(=O)CC5CCSS5)cc34)C#N)cc2Cl)c1	InChI=1S/C28H22ClFN4O2S2/c29-24-12-21(5-7-26(24)36-16-17-2-1-3-19(30)10-17)34-28-18(14-31)15-32-25-6-4-20(11-23(25)28)33-27(35)13-22-8-9-37-38-22/h1-7,10-12,15,22H,8-9,13,16H2,(H,32,34)(H,33,35)	FCVXPCQHDKWFDB-UHFFFAOYSA-N	373722	US10246444, Example 62	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373722	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373722&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236809	404342808							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742555	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C[C@H]1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373704	US10246444, Example 81	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373704	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373704&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135237001	404342791							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742558	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373705	US10246444, Example 82	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373705&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236450	404342792							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742561	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C[C@@H]1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373708	US10246444, Example 85	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373708	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373708&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236518	404342794					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742564	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C[C@H]1CCSS1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-9-21(4-5-28(25)41-16-18-2-1-3-20(33)8-18)36-31-19(13-34)14-35-26-12-29(42-17-22(39)15-38)27(11-24(26)31)37-30(40)10-23-6-7-43-44-23/h1-5,8-9,11-12,14,22-23,38-39H,6-7,10,15-17H2,(H,35,36)(H,37,40)	KVMBBUXCOHWOBJ-UHFFFAOYSA-N	373709	US10246444, Example 86	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373709	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373709&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236536	404342795					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742567	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CSSC1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-8-22(4-5-28(25)41-14-18-2-1-3-21(33)6-18)36-31-20(11-34)12-35-26-10-29(42-15-23(39)13-38)27(9-24(26)31)37-30(40)7-19-16-43-44-17-19/h1-6,8-10,12,19,23,38-39H,7,13-17H2,(H,35,36)(H,37,40)	UVWRRZRGHPHHLL-UHFFFAOYSA-N	373723	US10246444, Example 90	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373723	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373723&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236611	404342809							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742569	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CSSC1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-8-22(4-5-28(25)41-14-18-2-1-3-21(33)6-18)36-31-20(11-34)12-35-26-10-29(42-15-23(39)13-38)27(9-24(26)31)37-30(40)7-19-16-43-44-17-19/h1-6,8-10,12,19,23,38-39H,7,13-17H2,(H,35,36)(H,37,40)	UVWRRZRGHPHHLL-UHFFFAOYSA-N	373712	US10246444, Example 92	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373712	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373712&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236945	404342798					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742572	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1 |r|	InChI=1S/C30H26ClFN4O5S2/c31-24-7-21(4-5-27(24)40-13-17-2-1-3-20(32)6-17)35-29-18(10-33)11-34-25-9-28(41-14-22(38)12-37)26(8-23(25)29)36-30(39)19-15-42-43-16-19/h1-9,11,19,22,37-38H,12-16H2,(H,34,35)(H,36,39)	CRSYKTDYLTZPGM-UHFFFAOYSA-N	373724	US10246444, Example 95	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373724	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373724&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236635	404342810							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742574	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1 |r|	InChI=1S/C30H26ClFN4O5S2/c31-24-7-21(4-5-27(24)40-13-17-2-1-3-20(32)6-17)35-29-18(10-33)11-34-25-9-28(41-14-22(38)12-37)26(8-23(25)29)36-30(39)19-15-42-43-16-19/h1-9,11,19,22,37-38H,12-16H2,(H,34,35)(H,36,39)	CRSYKTDYLTZPGM-UHFFFAOYSA-N	373725	US10246444, Example 98	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373725	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373725&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236566	404342811					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742576	COc1cc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2cc1NC(=O)C1CSSC1	InChI=1S/C26H25N5O3S2/c1-15-8-18(5-7-23(15)34-19-6-4-16(2)27-11-19)30-25-20-9-22(31-26(32)17-12-35-36-13-17)24(33-3)10-21(20)28-14-29-25/h4-11,14,17H,12-13H2,1-3H3,(H,31,32)(H,28,29,30)	MWYCHGNJEPIBLU-UHFFFAOYSA-N	373726	US10246444, Example 104	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373726	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373726&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236597	404342812							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742579	COc1cc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2cc1NC(=O)CC1CCSS1	InChI=1S/C27H27N5O3S2/c1-16-10-18(5-7-24(16)35-19-6-4-17(2)28-14-19)31-27-21-12-23(25(34-3)13-22(21)29-15-30-27)32-26(33)11-20-8-9-36-37-20/h4-7,10,12-15,20H,8-9,11H2,1-3H3,(H,32,33)(H,29,30,31)	FAGAHRRIHCAACY-UHFFFAOYSA-N	373727	US10246444, Example 105	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373727	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373727&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236905	404342813							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742582	COc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C(CSC(N)=O)CSC(N)=O	InChI=1S/C28H26ClFN6O5S2/c1-40-24-10-21-19(9-22(24)36-26(37)16(12-42-27(31)38)13-43-28(32)39)25(34-14-33-21)35-18-5-6-23(20(29)8-18)41-11-15-3-2-4-17(30)7-15/h2-10,14,16H,11-13H2,1H3,(H2,31,38)(H2,32,39)(H,36,37)(H,33,34,35)	LBQIDXXDCFMBTI-UHFFFAOYSA-N	373728	US10246444, Example 109	Epidermal growth factor receptor	Homo sapiens		 50							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373728	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373728&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			145866023	404342814							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742584	COc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1	InChI=1S/C26H22ClFN4O3S2/c1-34-24-10-21-19(9-22(24)32-26(33)16-12-36-37-13-16)25(30-14-29-21)31-18-5-6-23(20(27)8-18)35-11-15-3-2-4-17(28)7-15/h2-10,14,16H,11-13H2,1H3,(H,32,33)(H,29,30,31)	NUBXIXHTTSQOKU-UHFFFAOYSA-N	373729	US10246444, Example 110	Epidermal growth factor receptor	Homo sapiens		 50							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373729	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373729&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236452	404342815							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742589	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CSSC1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-8-22(4-5-28(25)41-14-18-2-1-3-21(33)6-18)36-31-20(11-34)12-35-26-10-29(42-15-23(39)13-38)27(9-24(26)31)37-30(40)7-19-16-43-44-17-19/h1-6,8-10,12,19,23,38-39H,7,13-17H2,(H,35,36)(H,37,40)	UVWRRZRGHPHHLL-UHFFFAOYSA-N	373723	US10246444, Example 90	Epidermal growth factor receptor	Homo sapiens		 50							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373723	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373723&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236611	404342809							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742594	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CSSC1 |r|	InChI=1S/C31H28ClFN4O5S2/c32-25-8-22(4-5-28(25)41-14-18-2-1-3-21(33)6-18)36-31-20(11-34)12-35-26-10-29(42-15-23(39)13-38)27(9-24(26)31)37-30(40)7-19-16-43-44-17-19/h1-6,8-10,12,19,23,38-39H,7,13-17H2,(H,35,36)(H,37,40)	UVWRRZRGHPHHLL-UHFFFAOYSA-N	373712	US10246444, Example 92	Epidermal growth factor receptor	Homo sapiens		 50							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373712	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373712&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236945	404342798					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742599	OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1 |r|	InChI=1S/C30H26ClFN4O5S2/c31-24-7-21(4-5-27(24)40-13-17-2-1-3-20(32)6-17)35-29-18(10-33)11-34-25-9-28(41-14-22(38)12-37)26(8-23(25)29)36-30(39)19-15-42-43-16-19/h1-9,11,19,22,37-38H,12-16H2,(H,34,35)(H,36,39)	CRSYKTDYLTZPGM-UHFFFAOYSA-N	373724	US10246444, Example 95	Epidermal growth factor receptor	Homo sapiens		 50							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373724	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373724&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236635	404342810							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
742602	OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1 |r|	InChI=1S/C30H26ClFN4O5S2/c31-24-7-21(4-5-27(24)40-13-17-2-1-3-20(32)6-17)35-29-18(10-33)11-34-25-9-28(41-14-22(38)12-37)26(8-23(25)29)36-30(39)19-15-42-43-16-19/h1-9,11,19,22,37-38H,12-16H2,(H,34,35)(H,36,39)	CRSYKTDYLTZPGM-UHFFFAOYSA-N	373725	US10246444, Example 98	Epidermal growth factor receptor	Homo sapiens		 50							US Patent		10.7270/Q2NC63HJ		aid1798244	US10246444	Mansour, TS	4/2/2019	1/21/2020	Sabila Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=373725	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=373725&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135236566	404342811					C02773		1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755658	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccccc2)cc1)C1CCCN(C1)C#N	InChI=1S/C22H22N6O2/c23-14-27-12-4-5-16(13-27)28-21(24)19(22(25)29)20(26-28)15-8-10-18(11-9-15)30-17-6-2-1-3-7-17/h1-3,6-11,16H,4-5,12-13,24H2,(H2,25,29)	HVZJCIZSFTWSMN-UHFFFAOYSA-N	377707	US10266513, Example 2::US10266513, Example 3::5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazole carboxamide::US10266513, Example 1::US10815213, Example 2	Epidermal growth factor receptor	Homo sapiens		 1710							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377707	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377707&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90118971	404346674							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755659	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(Cl)cc2)cc1)C1CCCN(C1)C#N	InChI=1S/C22H21ClN6O2/c23-15-5-9-18(10-6-15)31-17-7-3-14(4-8-17)20-19(22(26)30)21(25)29(27-20)16-2-1-11-28(12-16)13-24/h3-10,16H,1-2,11-12,25H2,(H2,26,30)	YQUQOLJFVODMTO-UHFFFAOYSA-N	377719	US10266513, Example 15::5-amino-3-[4-(4-chlorophenoxy)phenyl]-1-(1-cyanopiperidin-3-yl)-1H-pyrazole-4-carboxamide::US10266513, Example 14::US10266513, Example 13::US10815213, Example 13	Epidermal growth factor receptor	Homo sapiens		 3890							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377719	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377719&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90118616	404346684							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755660	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(F)cc2F)cc1)C1CCCN(C1)C#N	InChI=1S/C22H20F2N6O2/c23-14-5-8-18(17(24)10-14)32-16-6-3-13(4-7-16)20-19(22(27)31)21(26)30(28-20)15-2-1-9-29(11-15)12-25/h3-8,10,15H,1-2,9,11,26H2,(H2,27,31)	SQFDBQCBXUWICP-UHFFFAOYSA-N	377731	US10266513, Example 26::US10266513, Example 27::5-amino-1-(1-cyanopiperidin-3-yl)-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazole-4-carboxamide::US10266513, Example 25::US10815213, Example 27	Epidermal growth factor receptor	Homo sapiens		 16800							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377731	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377731&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90118961	404346690							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755661	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(Cl)cn2)cc1)C1CCCN(C1)C#N	InChI=1S/C21H20ClN7O2/c22-14-5-8-17(26-10-14)31-16-6-3-13(4-7-16)19-18(21(25)30)20(24)29(27-19)15-2-1-9-28(11-15)12-23/h3-8,10,15H,1-2,9,11,24H2,(H2,25,30)	HECPFMSMYZURCE-UHFFFAOYSA-N	377814	US10266513, Example 110::5-amino-3-(4-((5-chloropyridin-2-yl)oxy)phenyl)-1-(1-cyanopiperidin-3-yl)-1H-pyrazole-4-carboxamide::US10266513, Example 109::US10266513, Example 108::US10815213, Example 110	Epidermal growth factor receptor	Homo sapiens		>15400							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377814&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90119305	404346756							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755662	NC(=O)c1c(N)n(nc1-c1ccc(Oc2cccc(n2)C(F)(F)F)cc1)C1CCCN(C1)C#N	InChI=1S/C22H20F3N7O2/c23-22(24,25)16-4-1-5-17(29-16)34-15-8-6-13(7-9-15)19-18(21(28)33)20(27)32(30-19)14-3-2-10-31(11-14)12-26/h1,4-9,14H,2-3,10-11,27H2,(H2,28,33)	LNMYMSAHQVYVMW-UHFFFAOYSA-N	377822	(R)-5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-((6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 117::US10266513, Example 116	Epidermal growth factor receptor	Homo sapiens		>26800							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377822&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90118741	404346760							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755663	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ncc(Cl)cc2F)cc1)[C@@H]1CCCN(C1)C#N |r|	InChI=1S/C21H19ClFN7O2/c22-13-8-16(23)21(27-9-13)32-15-5-3-12(4-6-15)18-17(20(26)31)19(25)30(28-18)14-2-1-7-29(10-14)11-24/h3-6,8-9,14H,1-2,7,10,25H2,(H2,26,31)	JJICHOVZOJORFF-UHFFFAOYSA-N	377824	(R)-5-amino-3-(4-((5-chloro-3-fluoropyridin-2-yl)oxy)phenyl)-1-(1-cyanopiperidin-3-yl)-1H-pyrazole-4-carboxamide::US10266513, Example 118::US10815213, Example 118	Epidermal growth factor receptor	Homo sapiens		>50000							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377824&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			74222509	404346761							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755664	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccccc2)cc1)[C@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C24H25N5O3/c1-2-20(30)28-14-6-7-17(15-28)29-23(25)21(24(26)31)22(27-29)16-10-12-19(13-11-16)32-18-8-4-3-5-9-18/h2-5,8-13,17H,1,6-7,14-15,25H2,(H2,26,31)	WTLRSSATGYETCG-UHFFFAOYSA-N	377832	1-[(3S)-1-acryloyl piperidin-3-yl]-5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 126::US9926299, 23::US10815213, Example 126	Epidermal growth factor receptor	Homo sapiens		 802							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377832&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			75204378	404346768							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755665	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(Cl)cc2)cc1)[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C24H24ClN5O3/c1-2-20(31)29-13-3-4-17(14-29)30-23(26)21(24(27)32)22(28-30)15-5-9-18(10-6-15)33-19-11-7-16(25)8-12-19/h2,5-12,17H,1,3-4,13-14,26H2,(H2,27,32)	HOUMQZGBNXSVNG-UHFFFAOYSA-N	377836	1-[(3R)-1-acryloyl piperidin-3-yl]-5-amino-3-[4-(4-chlorophenoxy)phenyl]-1H-pyrazole-4-carboxamide::US10266513, Example 130	Epidermal growth factor receptor	Homo sapiens		 7.90							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377836&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90119264	404346772							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755666	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(Cl)cc2)cc1)[C@@H]1CCCN(C1)C(=O)\C=C\CO |r|	InChI=1S/C25H26ClN5O4/c26-17-7-11-20(12-8-17)35-19-9-5-16(6-10-19)23-22(25(28)34)24(27)31(29-23)18-3-1-13-30(15-18)21(33)4-2-14-32/h2,4-12,18,32H,1,3,13-15,27H2,(H2,28,34)	IYXJXFBKVKQMBJ-UHFFFAOYSA-N	377837	5-amino-3-[4-(4-chlorophenoxy)phenyl]-1-{(3R)-1-[(2E)-4-hydroxybut-2-enoyl]piperidin-3-yl}-1H-pyrazole-4-carboxamide::US10266513, Example 131	Epidermal growth factor receptor	Homo sapiens		 2200							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377837&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			90119519	404346773							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755667	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(F)cc2F)cc1)C1CCCN(C1)C(=O)C=C	InChI=1S/C24H23F2N5O3/c1-2-20(32)30-11-3-4-16(13-30)31-23(27)21(24(28)33)22(29-31)14-5-8-17(9-6-14)34-19-10-7-15(25)12-18(19)26/h2,5-10,12,16H,1,3-4,11,13,27H2,(H2,28,33)	MDHXIRVUKGSUFJ-UHFFFAOYSA-N	377842	1-[(3S)-1-acryloyl piperidin-3-yl]-5-amino-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazole-4-carboxamide::US10266513, Example 137::US10266513, Example 136::US10815213, Example 137	Epidermal growth factor receptor	Homo sapiens		 214							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377842&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445268	404346778							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755668	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(F)cc2F)cc1)C1CCCN(C1)C(=O)C=C	InChI=1S/C24H23F2N5O3/c1-2-20(32)30-11-3-4-16(13-30)31-23(27)21(24(28)33)22(29-31)14-5-8-17(9-6-14)34-19-10-7-15(25)12-18(19)26/h2,5-10,12,16H,1,3-4,11,13,27H2,(H2,28,33)	MDHXIRVUKGSUFJ-UHFFFAOYSA-N	377842	1-[(3S)-1-acryloyl piperidin-3-yl]-5-amino-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazole-4-carboxamide::US10266513, Example 137::US10266513, Example 136::US10815213, Example 137	Epidermal growth factor receptor	Homo sapiens		 25.6							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377842&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445268	404346778							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755669	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(F)cc2F)cc1)C1CCCN(C1)C(=O)\C=C\C(F)F	InChI=1S/C25H23F4N5O3/c26-15-5-8-19(18(27)12-15)37-17-6-3-14(4-7-17)23-22(25(31)36)24(30)34(32-23)16-2-1-11-33(13-16)21(35)10-9-20(28)29/h3-10,12,16,20H,1-2,11,13,30H2,(H2,31,36)	KSNRPWDSUMXQLE-UHFFFAOYSA-N	377850	5-amino-1-{(3R)-1-[(2E)-4,4-difluorobut-2-enoyl]piperidin-3-yl}-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazole-4-carboxamide::US10266513, Example 144::US10815213, Example 144	Epidermal growth factor receptor	Homo sapiens		 274							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377850&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445273	404346785							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755670	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(F)cc2F)cc1)C1CCCN(C1)C(=O)\C=C\CF	InChI=1S/C25H24F3N5O3/c26-11-1-4-21(34)32-12-2-3-17(14-32)33-24(29)22(25(30)35)23(31-33)15-5-8-18(9-6-15)36-20-10-7-16(27)13-19(20)28/h1,4-10,13,17H,2-3,11-12,14,29H2,(H2,30,35)	FUHUKPVSBLOKHW-UHFFFAOYSA-N	377851	5-amino-3-[4-(2,4-difluorophenoxy)phenyl]-1-{(3R)-1-[(2E)-4-fluorobut-2-enoyl]piperidin-3-yl}-1H-pyrazole-4-carboxamide::US10266513, Example 145	Epidermal growth factor receptor	Homo sapiens		 2180							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377851&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445276	404346786							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755671	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(F)cc2F)cc1)C1CCCN(C1)C(=O)\C=C\CO	InChI=1S/C25H25F2N5O4/c26-16-7-10-20(19(27)13-16)36-18-8-5-15(6-9-18)23-22(25(29)35)24(28)32(30-23)17-3-1-11-31(14-17)21(34)4-2-12-33/h2,4-10,13,17,33H,1,3,11-12,14,28H2,(H2,29,35)	LBHJIGUWWMPNNW-UHFFFAOYSA-N	377857	5-am no-3-[4-(2,4-difluorophenoxy)phenyl]-1-{(3R)-1-[(2E)-4-hydroxybut-2-enoyl]-piperidin-3-yl}-1H-pyrazole-4-carboxamide::US10266513, Example 151	Epidermal growth factor receptor	Homo sapiens		 12100							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377857	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377857&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445279	404346792							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755672	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ncc(Cl)cc2F)cc1)C1CCCN(C1)C(=O)C=C	InChI=1S/C23H22ClFN6O3/c1-2-18(32)30-9-3-4-15(12-30)31-21(26)19(22(27)33)20(29-31)13-5-7-16(8-6-13)34-23-17(25)10-14(24)11-28-23/h2,5-8,10-11,15H,1,3-4,9,12,26H2,(H2,27,33)	YMFKLMVUBGVUPG-UHFFFAOYSA-N	377859	1-[(3R)-1-acryloyl piperidin-3-yl]-5-amino-3-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenyl}-1H-pyrazole-4-carboxamide::US10266513, Example 153	Epidermal growth factor receptor	Homo sapiens		 2.90							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377859	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377859&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445281	404346794							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755673	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ncc(Cl)cc2F)cc1)C1CCCN(C1)C(=O)\C=C\C(F)F	InChI=1S/C24H22ClF3N6O3/c25-14-10-17(26)24(31-11-14)37-16-5-3-13(4-6-16)21-20(23(30)36)22(29)34(32-21)15-2-1-9-33(12-15)19(35)8-7-18(27)28/h3-8,10-11,15,18H,1-2,9,12,29H2,(H2,30,36)	LSAYNPKQQQDTQW-UHFFFAOYSA-N	377861	5-amino-3-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenyl}-1-{(3R)-1-[(2E)-4,4-difluorobut-2-enoyl]piperidin-3-yl}-1H-pyrazole-4-carboxamide::US10266513, Example 155	Epidermal growth factor receptor	Homo sapiens		 106							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377861	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377861&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445282	404346796							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755674	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ncc(Cl)cc2F)cc1)C1CCCN(C1)C(=O)\C=C\CF	InChI=1S/C24H23ClF2N6O3/c25-15-11-18(27)24(30-12-15)36-17-7-5-14(6-8-17)21-20(23(29)35)22(28)33(31-21)16-3-2-10-32(13-16)19(34)4-1-9-26/h1,4-8,11-12,16H,2-3,9-10,13,28H2,(H2,29,35)	ANQSRGWBVINOHT-UHFFFAOYSA-N	377862	5-amino-3-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenyl}-1-{(3R)-1-[(2E)-4-fluorobut-2-enoyl]piperidin-3-yl}-1H-pyrazole-4-carboxamide::US10266513, Example 156	Epidermal growth factor receptor	Homo sapiens		 381							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377862	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377862&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445283	404346797							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755675	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(Cl)cn2)cc1)C1CCCN(C1)C(=O)C=C	InChI=1S/C23H23ClN6O3/c1-2-19(31)29-11-3-4-16(13-29)30-22(25)20(23(26)32)21(28-30)14-5-8-17(9-6-14)33-18-10-7-15(24)12-27-18/h2,5-10,12,16H,1,3-4,11,13,25H2,(H2,26,32)	OUKIICLWCIXIIL-UHFFFAOYSA-N	377863	1-[(3R)-1-acryloyl piperidin-3-yl]-5-amino-3-{4-[(5-chloropyridin-2-yl)oxy]phenyl}-1H-pyrazole-4-carboxamide::US10266513, Example 157	Epidermal growth factor receptor	Homo sapiens		 29.7							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377863	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377863&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445284	404346798							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755676	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(Cl)cn2)cc1)C1CCCN(C1)C(=O)\C=C\C(F)F	InChI=1S/C24H23ClF2N6O3/c25-15-5-9-19(30-12-15)36-17-6-3-14(4-7-17)22-21(24(29)35)23(28)33(31-22)16-2-1-11-32(13-16)20(34)10-8-18(26)27/h3-10,12,16,18H,1-2,11,13,28H2,(H2,29,35)	RBODKSYPSRHVMB-UHFFFAOYSA-N	377865	5-amino-3-{4-[(5-chloropyridin-2-yl)oxy]phenyl}-1-{(3R)-1-[(2E)-4,4-difluorobut-2-enoyl]piperidin-3-yl}-1H-pyrazole-4-carboxamide::US10266513, Example 159	Epidermal growth factor receptor	Homo sapiens		 311							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377865	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377865&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445286	404346800							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755677	NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(Cl)cn2)cc1)C1CCCN(C1)C(=O)\C=C\CF	InChI=1S/C24H24ClFN6O3/c25-16-7-10-19(29-13-16)35-18-8-5-15(6-9-18)22-21(24(28)34)23(27)32(30-22)17-3-2-12-31(14-17)20(33)4-1-11-26/h1,4-10,13,17H,2-3,11-12,14,27H2,(H2,28,34)	LXSBUVPAJOBMGO-UHFFFAOYSA-N	377866	5-amino-3-{4-[(5-chloropyridin-2-yl)oxy]phenyl}-1-{(3R)-1-[(2E)-4,4-difluorobut-2-enoyl]piperidin-3-yl}-1H-pyrazole-4-carboxamide::US10266513, Example 160::US10815213, Example 160	Epidermal growth factor receptor	Homo sapiens		 890							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377866	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377866&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445288	404346801							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755678	NC(=O)c1c(N)n(nc1-c1ccc(Oc2cccc(n2)C(F)(F)F)cc1)C1CCCN(C1)C(=O)C=C	InChI=1S/C24H23F3N6O3/c1-2-19(34)32-12-4-5-15(13-32)33-22(28)20(23(29)35)21(31-33)14-8-10-16(11-9-14)36-18-7-3-6-17(30-18)24(25,26)27/h2-3,6-11,15H,1,4-5,12-13,28H2,(H2,29,35)	PLKCSLFGEHRYBE-UHFFFAOYSA-N	377867	1-[(3R)-1-acryloyl piperidin-3-yl]-5-amino-3-(4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 161::US10815213, Example 161	Epidermal growth factor receptor	Homo sapiens		 89.8							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377867&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445297	404346802							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755679	NC(=O)c1c(N)n(nc1-c1ccc(Oc2cccc(n2)C(F)(F)F)cc1)C1CCCN(C1)C(=O)\C=C\CO	InChI=1S/C25H25F3N6O4/c26-25(27,28)18-5-1-6-19(31-18)38-17-10-8-15(9-11-17)22-21(24(30)37)23(29)34(32-22)16-4-2-12-33(14-16)20(36)7-3-13-35/h1,3,5-11,16,35H,2,4,12-14,29H2,(H2,30,37)	VQBKLKLRBAFOAA-UHFFFAOYSA-N	377868	5-amino-1-{(3R)-1-[(2E)-4-hydroxybut-2-enoyl]piperidin-3-yl}-3-(4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 162::US10815213, Example 162	Epidermal growth factor receptor	Homo sapiens		 14100							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377868&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445296	404346803							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755680	NC(=O)c1c(N)n(nc1-c1ccc(Oc2cccc(n2)C(F)(F)F)cc1)C1CCCN(C1)C(=O)\C=C\C(F)F	InChI=1S/C25H23F5N6O3/c26-18(27)10-11-20(37)35-12-2-3-15(13-35)36-23(31)21(24(32)38)22(34-36)14-6-8-16(9-7-14)39-19-5-1-4-17(33-19)25(28,29)30/h1,4-11,15,18H,2-3,12-13,31H2,(H2,32,38)	UYAWNZFVHHTQLY-UHFFFAOYSA-N	377869	5-amino-1-{(3R)-1-[(2E)-4,4-difluorobut-2-enoyl]piperidin-3-yl}-3-(4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 163::US10815213, Example 163	Epidermal growth factor receptor	Homo sapiens		 1190							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377869&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445292	404346804							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
755681	NC(=O)c1c(N)n(nc1-c1ccc(Oc2cccc(n2)C(F)(F)F)cc1)C1CCCN(C1)C(=O)\C=C\CF	InChI=1S/C25H24F4N6O3/c26-12-2-7-20(36)34-13-3-4-16(14-34)35-23(30)21(24(31)37)22(33-35)15-8-10-17(11-9-15)38-19-6-1-5-18(32-19)25(27,28)29/h1-2,5-11,16H,3-4,12-14,30H2,(H2,31,37)	HPSTWVAKYLNLGT-UHFFFAOYSA-N	377870	5-amino-1-{(3R)-1-[(2E)-4-fluorobut-2-enoyl]piperidin-3-yl}-3-(4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 164::US10815213, Example 164	Epidermal growth factor receptor	Homo sapiens		 3360							US Patent		10.7270/Q2P271FD		aid1798381	US10266513	Springer, JR; Devadas, B; Garland, DJ; Grapperhaus, ML; Han, S; Hockerman, SL; Hughes, RO; Saiah, E; Schnute, ME; Selness, SR; Walker, DP; Wan, Z; Xing, L; Zapf, CW; Schmidt, MA	4/23/2019	2/7/2020	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=377870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=377870&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118445294	404346805							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
756991	CCn1nc(C#Cc2cc(ccc2C)C(=O)Nc2ccc(CN3CCN(C)CC3)c(c2)C(F)(F)F)c2c(N)ncnc12	InChI=1S/C30H31F3N8O/c1-4-41-28-26(27(34)35-18-36-28)25(38-41)10-8-20-15-21(6-5-19(20)2)29(42)37-23-9-7-22(24(16-23)30(31,32)33)17-40-13-11-39(3)12-14-40/h5-7,9,15-16,18H,4,11-14,17H2,1-3H3,(H,37,42)(H2,34,35,36)	BNRXMSGHPVYSDK-UHFFFAOYSA-N	50086441	CHEMBL3426225::US10266537, Compound 3	Epidermal growth factor receptor	Homo sapiens		 3518							US Patent		10.7270/Q21C2065		aid1798403	US10266537	Yang, S; Wei, Y	4/23/2019	2/7/2020	St. Chuan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118737057	103985649		CHEMBL3426225					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
756992	Cc1ccc(NC(=O)c2ccc(C)c(c2)C(F)(F)F)cc1C#Cc1nn([C@H]2CC[C@H](O)CC2)c2ncnc(N)c12 |r,wU:26.27,wD:29.31,(-5.46,5.4,;-3.98,5.8,;-3.58,7.29,;-2.09,7.69,;-1,6.6,;.49,7,;1.57,5.91,;1.18,4.42,;3.06,6.31,;3.46,7.79,;4.95,8.19,;6.04,7.1,;7.53,7.5,;5.64,5.62,;4.15,5.22,;6.73,4.53,;8.22,4.93,;6.33,3.04,;7.82,3.44,;-1.4,5.11,;-2.89,4.71,;-3.29,3.22,;-3.68,1.74,;-4.08,.25,;-3.18,-1,;-4.08,-2.24,;-3.68,-3.73,;-2.2,-4.13,;-1.8,-5.62,;-2.89,-6.7,;-2.49,-8.19,;-4.38,-6.31,;-4.77,-4.82,;-5.55,-1.77,;-6.88,-2.54,;-8.22,-1.77,;-8.22,-.23,;-6.88,.54,;-6.88,2.08,;-5.55,-.23,)|	InChI=1S/C29H27F3N6O2/c1-16-4-7-20(36-28(40)19-5-3-17(2)23(14-19)29(30,31)32)13-18(16)6-12-24-25-26(33)34-15-35-27(25)38(37-24)21-8-10-22(39)11-9-21/h3-5,7,13-15,21-22,39H,8-11H2,1-2H3,(H,36,40)(H2,33,34,35)	YHVHYWYQEFELOW-UHFFFAOYSA-N	378885	US10266537, Compound 93	Epidermal growth factor receptor	Homo sapiens		 651							US Patent		10.7270/Q21C2065		aid1798403	US10266537	Yang, S; Wei, Y	4/23/2019	2/7/2020	St. Chuan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=378885	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=378885&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122419211	404338880							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761707	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1	InChI=1S/C25H31N9O2/c1-7-22(35)28-18-12-19(21(36-6)13-20(18)33(4)11-10-32(2)3)29-25-30-23(16-14-27-34(5)15-16)17-8-9-26-24(17)31-25/h7-9,12-15H,1,10-11H2,2-6H3,(H,28,35)(H2,26,29,30,31)	RGRJZPKFWSMZRB-UHFFFAOYSA-N	380783	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidn-2-ylamino)phenyl)acrylamide ::US9890168, Compound 9::US9890168, Compound 1	Epidermal growth factor receptor	Homo sapiens		 393							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380783&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685279	404850244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761709	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(N2CCOCC2)c2cc[nH]c2n1	InChI=1S/C25H34N8O3/c1-6-22(34)27-18-15-19(21(35-5)16-20(18)32(4)10-9-31(2)3)28-25-29-23-17(7-8-26-23)24(30-25)33-11-13-36-14-12-33/h6-8,15-16H,1,9-14H2,2-5H3,(H,27,34)(H2,26,28,29,30)	YXQWTVNIMOQXTN-UHFFFAOYSA-N	380784	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acrylamide ::US9890168, Compound 2	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380784&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685042	404850245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761711	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(OC2CN(C2)S(C)(=O)=O)c2ccn(CO)c2n1	InChI=1S/C26H36N8O6S/c1-7-23(36)27-19-12-20(22(39-5)13-21(19)32(4)11-10-31(2)3)28-26-29-24-18(8-9-33(24)16-35)25(30-26)40-17-14-34(15-17)41(6,37)38/h7-9,12-13,17,35H,1,10-11,14-16H2,2-6H3,(H,27,36)(H,28,29,30)	LIKBOPHRCVGRML-UHFFFAOYSA-N	380785	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-(methylsulfonyl)azetidin-3-yloxy)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acryl amide ::US9890168, Compound 3	Epidermal growth factor receptor	Homo sapiens		 88.0							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380785&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			130327597	404850246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761713	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnc3n(C)ccc3c2)c2cc[nH]c2n1	InChI=1S/C29H33N9O2/c1-7-25(39)32-21-15-22(24(40-6)16-23(21)37(4)13-12-36(2)3)33-29-34-26(20-8-10-30-27(20)35-29)19-14-18-9-11-38(5)28(18)31-17-19/h7-11,14-17H,1,12-13H2,2-6H3,(H,32,39)(H2,30,33,34,35)	BCRGWDZMCMRCPL-UHFFFAOYSA-N	380786	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acrylamide::US9890168, Compound 4	Epidermal growth factor receptor	Homo sapiens		 39.0							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380786&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685131	404850247							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761715	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cn(C)c3ccccc23)c2cc[nH]c2n1	InChI=1S/C30H34N8O2/c1-7-27(39)32-22-16-23(26(40-6)17-25(22)37(4)15-14-36(2)3)33-30-34-28(20-12-13-31-29(20)35-30)21-18-38(5)24-11-9-8-10-19(21)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,32,39)(H2,31,33,34,35)	SHEALWKRXIPONQ-UHFFFAOYSA-N	380787	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acrylamide::US9890168, Compound 5	Epidermal growth factor receptor	Homo sapiens		 15.0							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380787&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685062	404850248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761717	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cccnc2)c2cc[nH]c2n1	InChI=1S/C26H30N8O2/c1-6-23(35)29-19-14-20(22(36-5)15-21(19)34(4)13-12-33(2)3)30-26-31-24(17-8-7-10-27-16-17)18-9-11-28-25(18)32-26/h6-11,14-16H,1,12-13H2,2-5H3,(H,29,35)(H2,28,30,31,32)	YKEZGADHKKBNFP-UHFFFAOYSA-N	380788	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(pyridin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-2ylamino)phenyl)acrylamide ::US9890168, Compound 6	Epidermal growth factor receptor	Homo sapiens		 347							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380788	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380788&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685281	404850249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761719	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2ccccc2)c2cc[nH]c2n1	InChI=1S/C27H31N7O2/c1-6-24(35)29-20-16-21(23(36-5)17-22(20)34(4)15-14-33(2)3)30-27-31-25(18-10-8-7-9-11-18)19-12-13-28-26(19)32-27/h6-13,16-17H,1,14-15H2,2-5H3,(H,29,35)(H2,28,30,31,32)	GTNZEAVPIDJENJ-UHFFFAOYSA-N	380789	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-phenyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acrylamide ::US9890168, Compound 7	Epidermal growth factor receptor	Homo sapiens		 315							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380789&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685282	404850250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761721	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1	InChI=1S/C25H31N9O2/c1-7-22(35)28-18-12-19(21(36-6)13-20(18)33(4)11-10-32(2)3)29-25-30-23(16-14-27-34(5)15-16)17-8-9-26-24(17)31-25/h7-9,12-15H,1,10-11H2,2-6H3,(H,28,35)(H2,26,29,30,31)	RGRJZPKFWSMZRB-UHFFFAOYSA-N	380783	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidn-2-ylamino)phenyl)acrylamide ::US9890168, Compound 9::US9890168, Compound 1	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380783&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685279	404850244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761723	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1	InChI=1S/C24H28N8O3/c1-6-21(33)27-18-11-17(19(34-5)12-20(18)35-10-9-31(2)3)28-24-29-22(15-13-26-32(4)14-15)16-7-8-25-23(16)30-24/h6-8,11-14H,1,9-10H2,2-5H3,(H,27,33)(H2,25,28,29,30)	IDDYTWUCWWJAHI-UHFFFAOYSA-N	380791	N-(2-(2-(dimethylamino)etboxy)-4-methoxy-5-(4-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acrylamide ::US9890168, Compound 10	Epidermal growth factor receptor	Homo sapiens		 578							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380791&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685153	404850251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761725	COc1cc(N2CC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1	InChI=1S/C25H29N9O2/c1-6-22(35)28-18-9-19(21(36-5)10-20(18)34-13-16(14-34)32(2)3)29-25-30-23(15-11-27-33(4)12-15)17-7-8-26-24(17)31-25/h6-12,16H,1,13-14H2,2-5H3,(H,28,35)(H2,26,29,30,31)	IBDIFACXSBCDLX-UHFFFAOYSA-N	380792	N-(2-(3-(dimethylamino)azetidin-1-yl)-4-methoxy-5-(4-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acrylamide Formate ::US9890168, Compound 11	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380792&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685287	404850252							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761727	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1	InChI=1S/C25H29N9O2/c1-5-22(35)28-18-12-19(21(36-4)13-20(18)34-10-8-32(2)9-11-34)29-25-30-23(16-14-27-33(3)15-16)17-6-7-26-24(17)31-25/h5-7,12-15H,1,8-11H2,2-4H3,(H,28,35)(H2,26,29,30,31)	XIXWCRPCSAQBGZ-UHFFFAOYSA-N	380793	N-(4-methoxy-5-(4-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-2-(4-methylpiperazin-1-yl)phenyl)acrylamide ::US9890168, Compound 12	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380793	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380793&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685288	404850253							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761729	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2c(Cl)c[nH]c2n1	InChI=1S/C25H28ClN9O2/c1-5-21(36)29-17-10-18(20(37-4)11-19(17)35-8-6-33(2)7-9-35)30-25-31-23(15-12-28-34(3)14-15)22-16(26)13-27-24(22)32-25/h5,10-14H,1,6-9H2,2-4H3,(H,29,36)(H2,27,30,31,32)	SWMRVGGZHLPPRA-UHFFFAOYSA-N	380794	N-(5-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-2-(4(dimethylamino)piperidin-1-yl)-4-methoxyphenyl)acrylamide::US9890168, Compound 13	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380794&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			145995517	404850254							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761731	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2c(C)c[nH]c2n1	InChI=1S/C28H35N9O2/c1-7-24(38)31-20-12-21(23(39-6)13-22(20)37-10-8-19(9-11-37)35(3)4)32-28-33-26(18-15-30-36(5)16-18)25-17(2)14-29-27(25)34-28/h7,12-16,19H,1,8-11H2,2-6H3,(H,31,38)(H2,29,32,33,34)	ALNHICJWLQIPOZ-UHFFFAOYSA-N	380795	N-(2-(4-(dimethylamino)piperidin-1-yl)-4-methoxy-5-(5-methyl-4-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)acryl amide ::US9890168, Compound 14	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380795&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685295	404850255							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761733	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12	InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)	DUYJMQONPNNFPI-UHFFFAOYSA-N	50029668	AZD-9291::Osimertinib::US10085983, Compound AZD-9291::US10227342, Example 24::US9890168, Compound AZD-9291::US11111233, Example AZD9291::WO2022090481, Example osimertinib::US20230322822, Compound AZD9291::US11896597, Compound AZD9291::US12410192, Compound Osimertinib	Epidermal growth factor receptor	Homo sapiens		 3.00							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029668&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			71496458	313065691			DB09330				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761735	CN(C)C/C=C/C(=O)Nc1cc2c(cc1O[C@H]3CCOC3)ncnc2Nc4ccc(c(c4)Cl)F	InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)	ULXXDDBFHOBEHA-UHFFFAOYSA-N	50322823	(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide::CHEMBL1173655::AFATINIB::US9388170, Afatinib::US10085983, Compound BIBW2992::US10196365, Afatinib::US9890168, Compound BIBW2992::US10435400, Compound BIBW2992::WO2022090481, Example afatinib::US11896597, Compound Afatinib::US20240358711, Compound Afatanib	Epidermal growth factor receptor	Homo sapiens		 1.000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322823&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0WM	4G5J	10184653	104144352		CHEMBL1173655	DB08916				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
761737	COc1cc(ccc1Nc1nc(-c2cccc(NC(=O)C=C)c2)c2cc[nH]c2n1)N(C)CCN(C)C	InChI=1S/C27H31N7O2/c1-6-24(35)29-19-9-7-8-18(16-19)25-21-12-13-28-26(21)32-27(31-25)30-22-11-10-20(17-23(22)36-5)34(4)15-14-33(2)3/h6-13,16-17H,1,14-15H2,2-5H3,(H,29,35)(H2,28,30,31,32)	ISMIIXOOZHPNPW-UHFFFAOYSA-N	380798	US9890168, Compound Comparative compound 1	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2PV6NPJ		aid1798474	US9890168	Lan, J; Jin, Y; Zhou, F; Lei, J; Wen, C; Zhang, Z; He, X	2/13/2018	2/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=380798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=380798&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118685308	404850257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
766869	Nc1ncnc2n(nc(C(=O)Nc3nc4ccccc4o3)c12)[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C21H20N8O3/c1-2-15(30)28-9-5-6-12(10-28)29-19-16(18(22)23-11-24-19)17(27-29)20(31)26-21-25-13-7-3-4-8-14(13)32-21/h2-4,7-8,11-12H,1,5-6,9-10H2,(H2,22,23,24)(H,25,26,31)	WUMMDJMYFAWMBN-UHFFFAOYSA-N	291282	US9580432, Example 13::US10280174, Compound A	Epidermal growth factor receptor	Homo sapiens		 16.9							US Patent		10.7270/Q26Q20K3		aid1798578	US10280174	Oshiumi, H	5/7/2019	2/21/2020	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291282	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291282&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118519887	381611587							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
766870	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C	InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)	XYFPWWZEPKGCCK-UHFFFAOYSA-N	1773	US8497277, 4::US8476284, 4::US9133201, 4::US9133201, 13::US9133201, 14::US9975882, comparative compound A::US10280174, Comparative Compound 1	Epidermal growth factor receptor	Homo sapiens		 1.30							US Patent		10.7270/Q26Q20K3		aid1798578	US10280174	Oshiumi, H	5/7/2019	2/21/2020	Taiho Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=1773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=1773&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			16126651	251974395							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782735	CC(=O)N1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Nc4cccc(c4)NC(=O)C=C)C(F)(F)F	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	US8975249, I-4::CO-1686::Rociletinib::AVL-301::CNX-419::Tube721::CHEMBL3545308::US10167264, Compound CO-1686::US9783524, CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 145							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDK,5XDL	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782737	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)n2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O	InChI=1S/C26H27F3N8O3/c1-4-23(39)33-21-6-5-7-22(32-21)34-24-18(26(27,28)29)15-30-25(35-24)31-19-9-8-17(14-20(19)40-3)37-12-10-36(11-13-37)16(2)38/h4-9,14-15H,1,10-13H2,2-3H3,(H3,30,31,32,33,34,35,39)	XOMJMNMWHARWMR-UHFFFAOYSA-N	391731	US10300058, Compound 1::pyrimidin-4-yl)amino)pyridin-2-yl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 323							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391731	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391731&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464927	404960095							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782739	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CC1)C(C)=O	InChI=1S/C28H29F3N6O3/c1-4-25(39)33-20-6-5-7-21(15-20)34-26-22(28(29,30)31)16-32-27(36-26)35-23-9-8-19(14-24(23)40-3)18-10-12-37(13-11-18)17(2)38/h4-9,14-16,18H,1,10-13H2,2-3H3,(H,33,39)(H2,32,34,35,36)	KBMUKKBYMBZSBI-UHFFFAOYSA-N	391732	US10300058, Compound 2::acrylamide 	Epidermal growth factor receptor	Homo sapiens		 552							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391732	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391732&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464928	404960096							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782741	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1=CCN(CC1)C(C)=O |t:34|	InChI=1S/C28H27F3N6O3/c1-4-25(39)33-20-6-5-7-21(15-20)34-26-22(28(29,30)31)16-32-27(36-26)35-23-9-8-19(14-24(23)40-3)18-10-12-37(13-11-18)17(2)38/h4-10,14-16H,1,11-13H2,2-3H3,(H,33,39)(H2,32,34,35,36)	GISJYRXMWDIIPZ-UHFFFAOYSA-N	391733	US10300058, Compound 3::N-(3-((2-((4-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 699							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391733	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391733&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464872	404960097							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782743	CC(=O)N1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Nc4cccc(c4)NC(=O)C=C)C(F)(F)F	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	US8975249, I-4::CO-1686::Rociletinib::AVL-301::CNX-419::Tube721::CHEMBL3545308::US10167264, Compound CO-1686::US9783524, CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 180							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDK,5XDL	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782745	COc1cc2CN(CCc2cc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C(C)=O	InChI=1S/C26H25F3N6O3/c1-4-23(37)31-18-6-5-7-19(12-18)32-24-20(26(27,28)29)13-30-25(34-24)33-21-10-16-8-9-35(15(2)36)14-17(16)11-22(21)38-3/h4-7,10-13H,1,8-9,14H2,2-3H3,(H,31,37)(H2,30,32,33,34)	HXPUBUWIOHZCKU-UHFFFAOYSA-N	391734	US10300058, Compound 11::N-(3-((2-((2-acetyl-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 640							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391734	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391734&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464885	404960098							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782747	CC(=O)N1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Nc4cccc(c4)NC(=O)C=C)C(F)(F)F	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	US8975249, I-4::CO-1686::Rociletinib::AVL-301::CNX-419::Tube721::CHEMBL3545308::US10167264, Compound CO-1686::US9783524, CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 180							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDK,5XDL	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782749	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)n2)n1)C(F)(F)F)C1CCN(CC1)C(C)=O	InChI=1S/C27H28F3N7O3/c1-4-24(39)34-22-6-5-7-23(33-22)35-25-19(27(28,29)30)15-31-26(36-25)32-20-9-8-18(14-21(20)40-3)17-10-12-37(13-11-17)16(2)38/h4-9,14-15,17H,1,10-13H2,2-3H3,(H3,31,32,33,34,35,36,39)	VWKFGMCZHYQJRN-UHFFFAOYSA-N	391735	US10300058, Compound 4::N-(6-((2-((4-(1-acetylpiperidin-4-yl)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)pyridin-2-yl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 423							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391735&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464946	404960099							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782751	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)n2)n1)C(F)(F)F)C1=CCN(CC1)C(C)=O |t:34|	InChI=1S/C27H26F3N7O3/c1-4-24(39)34-22-6-5-7-23(33-22)35-25-19(27(28,29)30)15-31-26(36-25)32-20-9-8-18(14-21(20)40-3)17-10-12-37(13-11-17)16(2)38/h4-10,14-15H,1,11-13H2,2-3H3,(H3,31,32,33,34,35,36,39)	CKERVRAKWMWOMR-UHFFFAOYSA-N	391736	US10300058, Compound 5::N-(6-((2-((4-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)pyridin-2-yl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 995							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391736	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391736&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464941	404960100							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782753	CC(=O)N1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Nc4cccc(c4)NC(=O)C=C)C(F)(F)F	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	US8975249, I-4::CO-1686::Rociletinib::AVL-301::CNX-419::Tube721::CHEMBL3545308::US10167264, Compound CO-1686::US9783524, CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 153000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDK,5XDL	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782755	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CC2CCC(C1)N2C(C)=O	InChI=1S/C29H30F3N7O3/c1-4-26(41)34-18-6-5-7-19(12-18)35-27-23(29(30,31)32)14-33-28(37-27)36-24-11-10-20(13-25(24)42-3)38-15-21-8-9-22(16-38)39(21)17(2)40/h4-7,10-14,21-22H,1,8-9,15-16H2,2-3H3,(H,34,41)(H2,33,35,36,37)	LRKRAUFHHJRZGI-UHFFFAOYSA-N	391737	US10300058, Compound 7::N-(3-((2-((4-(8-acetyl-3,8-diazabicyclo[3.2.1]octan-3-yl)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 332000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391737	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391737&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464930	404960101							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782757	COc1c(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)ccc2CCN(Cc12)C(C)=O	InChI=1S/C26H25F3N6O3/c1-4-22(37)31-17-6-5-7-18(12-17)32-24-20(26(27,28)29)13-30-25(34-24)33-21-9-8-16-10-11-35(15(2)36)14-19(16)23(21)38-3/h4-9,12-13H,1,10-11,14H2,2-3H3,(H,31,37)(H2,30,32,33,34)	KDFJJNDCCSIGGF-UHFFFAOYSA-N	391738	US10300058, Compound 17::N-(3-((2-((2-acetyl-8-methoxy-1,2,3,4-tetrahydroisoquinoline-7-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 1369000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391738	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391738&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464890	404960102							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782759	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CCF)C(=O)C1	InChI=1S/C28H28F4N6O3/c1-3-24(39)34-19-5-4-6-20(15-19)35-26-21(28(30,31)32)16-33-27(37-26)36-22-8-7-17(13-23(22)41-2)18-9-11-38(12-10-29)25(40)14-18/h3-8,13,15-16,18H,1,9-12,14H2,2H3,(H,34,39)(H2,33,35,36,37)	QKNILDDOBRHBTL-UHFFFAOYSA-N	391739	US10300058, Compound 23::methyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 294000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391739&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464900	404960103							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782761	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CC1)C(=O)CCF	InChI=1S/C29H30F4N6O3/c1-3-25(40)35-20-5-4-6-21(16-20)36-27-22(29(31,32)33)17-34-28(38-27)37-23-8-7-19(15-24(23)42-2)18-10-13-39(14-11-18)26(41)9-12-30/h3-8,15-18H,1,9-14H2,2H3,(H,35,40)(H2,34,36,37,38)	UEHPBAFYFOFYLA-UHFFFAOYSA-N	391740	US10300058, Compound 25::N-(3-((2-((4-(1-(3-fluoropropionyl)piperidin-4-yl)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 683000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391740	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391740&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464923	404960104							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782763	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CCF)CC1	InChI=1S/C28H30F4N6O2/c1-3-25(39)34-20-5-4-6-21(16-20)35-26-22(28(30,31)32)17-33-27(37-26)36-23-8-7-19(15-24(23)40-2)18-9-12-38(13-10-18)14-11-29/h3-8,15-18H,1,9-14H2,2H3,(H,34,39)(H2,33,35,36,37)	GWNADOKGQKZFAK-UHFFFAOYSA-N	391741	US10300058, Compound 26::pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 25000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391741	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391741&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			129051738	404960105							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782765	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CC1)S(C)(=O)=O	InChI=1S/C27H29F3N6O4S/c1-4-24(37)32-19-6-5-7-20(15-19)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-18(14-23(22)40-2)17-10-12-36(13-11-17)41(3,38)39/h4-9,14-17H,1,10-13H2,2-3H3,(H,32,37)(H2,31,33,34,35)	WQGDMILUIXEUMW-UHFFFAOYSA-N	391742	US10300058, Compound 27::N-(3-((2-((2-methoxy-4-(1-(methylsulfonyl)piperidin-4-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 871000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391742	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391742&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464922	404960106							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782767	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCC(CC1)N1CCOCC1	InChI=1S/C30H34F3N7O3/c1-3-27(41)35-20-5-4-6-21(17-20)36-28-24(30(31,32)33)19-34-29(38-28)37-25-8-7-23(18-26(25)42-2)39-11-9-22(10-12-39)40-13-15-43-16-14-40/h3-8,17-19,22H,1,9-16H2,2H3,(H,35,41)(H2,34,36,37,38)	XZALXIFAYPBZQA-UHFFFAOYSA-N	391743	US10300058, Compound 28::N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 73000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391743	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391743&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91972029	404960107							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782769	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(C)CC1	InChI=1S/C27H29F3N6O2/c1-4-24(37)32-19-6-5-7-20(15-19)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-18(14-23(22)38-3)17-10-12-36(2)13-11-17/h4-9,14-17H,1,10-13H2,2-3H3,(H,32,37)(H2,31,33,34,35)	VSZYMKBEJOLAEM-UHFFFAOYSA-N	391744	US10300058, Compound 29::N-(3-((2-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 11000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391744	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391744&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464949	404960108							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782771	CC(=O)N1CCc2c(C1)cccc2Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C25H23F3N6O2/c1-3-22(36)30-17-7-5-8-18(12-17)31-23-20(25(26,27)28)13-29-24(33-23)32-21-9-4-6-16-14-34(15(2)35)11-10-19(16)21/h3-9,12-13H,1,10-11,14H2,2H3,(H,30,36)(H2,29,31,32,33)	MSISUFHZEJVFKH-UHFFFAOYSA-N	391745	US10300058, Compound 37::N-(3-((2-((2-acetyl-1,2,3,4-tetrahydroisoquinoline-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 1284000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391745	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391745&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464917	404960109							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782773	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CC1)C1COC1	InChI=1S/C29H31F3N6O3/c1-3-26(39)34-20-5-4-6-21(14-20)35-27-23(29(30,31)32)15-33-28(37-27)36-24-8-7-19(13-25(24)40-2)18-9-11-38(12-10-18)22-16-41-17-22/h3-8,13-15,18,22H,1,9-12,16-17H2,2H3,(H,34,39)(H2,33,35,36,37)	HTTGSHFJWXPPKC-UHFFFAOYSA-N	391746	US10300058, Compound 41::N-(3-((2-((2-methoxy-4-(1-(oxetan-3-yl)piperidin-4-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 82000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391746	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391746&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464972	404960110							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
782775	COc1cc(OCCCS(C)(=O)=O)ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F	InChI=1S/C25H26F3N5O5S/c1-4-22(34)30-16-7-5-8-17(13-16)31-23-19(25(26,27)28)15-29-24(33-23)32-20-10-9-18(14-21(20)37-2)38-11-6-12-39(3,35)36/h4-5,7-10,13-15H,1,6,11-12H2,2-3H3,(H,30,34)(H2,29,31,32,33)	KEYMOZJHSVZVMG-UHFFFAOYSA-N	391747	US10300058, Compound 43::N-(3-((2-((2-methoxy-4-(3-(methylsulfonyl)propoxy)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 159000							US Patent		10.7270/Q2P84F65		aid1798869	US10300058	Wu, F	5/28/2019	3/25/2020	Xuanzhu Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391747&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118464975	404960111							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793925	Cc1cccc(Nc2ccnc(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C20H19N5O/c1-3-19(26)23-16-8-5-9-17(13-16)24-20-21-11-10-18(25-20)22-15-7-4-6-14(2)12-15/h3-13H,1H2,2H3,(H,23,26)(H2,21,22,24,25)	SYRFNUJQNYVPCA-UHFFFAOYSA-N	397142	US9987276, Compound I-1::US10596172, Compound I-1::US10828300, Compound I-1::US11351168, Compound I-1	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397142	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397142&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44596105	405267210							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793926	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)ncc2C)c1	InChI=1S/C21H21N5O/c1-4-19(27)23-17-9-6-10-18(12-17)25-21-22-13-15(3)20(26-21)24-16-8-5-7-14(2)11-16/h4-13H,1H2,2-3H3,(H,23,27)(H2,22,24,25,26)	WQDMXYSIBUJDCH-UHFFFAOYSA-N	397143	US9987276, Compound I-2::US10596172, Compound I-8::US10828300, Compound I-2::US11351168, Compound I-2	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397143	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397143&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44596106	405267211							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793927	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)ncc2F)c1	InChI=1S/C20H18FN5O/c1-3-18(27)23-15-8-5-9-16(11-15)25-20-22-12-17(21)19(26-20)24-14-7-4-6-13(2)10-14/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	PBMBZFMNHMPCMZ-UHFFFAOYSA-N	397288	US9987276, Compound I-3::US10596172, Compound I-3::US10828300, Compound I-3::US11351168, Compound I-3	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397288	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397288&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44596107	405267353							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793928	CN(C)C\C=C\C(=O)Nc1cccc(Nc2ncc(F)c(Nc3cccc(C)c3)n2)c1	InChI=1S/C23H25FN6O/c1-16-7-4-8-17(13-16)27-22-20(24)15-25-23(29-22)28-19-10-5-9-18(14-19)26-21(31)11-6-12-30(2)3/h4-11,13-15H,12H2,1-3H3,(H,26,31)(H2,25,27,28,29)	QHBQTYVTHVMJKQ-UHFFFAOYSA-N	397144	US9987276, Compound I-4::US9987276, Compound I-360::US10596172, Compound I-4::US10828300, Compound I-4::US11351168, Compound I-4	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397144	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397144&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44596109	405267212							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793929	Cc1cnc(Nc2cccc(NC(=O)C=C)c2)nc1Nc1ccccc1	InChI=1S/C20H19N5O/c1-3-18(26)22-16-10-7-11-17(12-16)24-20-21-13-14(2)19(25-20)23-15-8-5-4-6-9-15/h3-13H,1H2,2H3,(H,22,26)(H2,21,23,24,25)	DRSGNONRPHLSEN-UHFFFAOYSA-N	397289	US9987276, Compound I-5::US10596172, Compound I-5::US10828300, Compound I-5::US11351168, Compound I-5	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397289	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397289&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44596108	405267354							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793930	Cc1cnc(Nc2ccccc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C20H19N5O/c1-3-18(26)22-16-10-7-11-17(12-16)23-19-14(2)13-21-20(25-19)24-15-8-5-4-6-9-15/h3-13H,1H2,2H3,(H,22,26)(H2,21,23,24,25)	ZKGDYELRUUQVJF-UHFFFAOYSA-N	397145	US9987276, Compound I-7::US10596172, Compound I-7::US10828300, Compound IR-7::US11351168, Compound I-7	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397145	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397145&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44545847	405267213							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793931	Cc1cccc(Nc2nc(Nc3cc(NC(=O)C=C)ccc3C)ncc2C)c1	InChI=1S/C22H23N5O/c1-5-20(28)24-18-10-9-15(3)19(12-18)26-22-23-13-16(4)21(27-22)25-17-8-6-7-14(2)11-17/h5-13H,1H2,2-4H3,(H,24,28)(H2,23,25,26,27)	FHSNRCNZHKJTOQ-UHFFFAOYSA-N	397290	US9987276, Compound I-8::US10828300, Compound I-8::US11351168, Compound I-8	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397290	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397290&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44593976	405267355							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793932	Cc1cnc(Nc2cccc(NC(=O)C=C)c2)nc1Nc1cccc(Br)c1	InChI=1S/C20H18BrN5O/c1-3-18(27)23-16-8-5-9-17(11-16)25-20-22-12-13(2)19(26-20)24-15-7-4-6-14(21)10-15/h3-12H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	AQVFAJITBRMHAU-UHFFFAOYSA-N	397291	US9987276, Compound I-9::US10596172, Compound I-9::US10828300, Compound I-9::US11351168, Compound I-9	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397291	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397291&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44593977	405267356							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793933	Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1ccc2CN(CCc2c1)S(=O)(=O)C1CC1	InChI=1S/C23H26N6O4S2/c1-15-13-25-23(27-18-3-2-4-21(12-18)34(24,30)31)28-22(15)26-19-6-5-17-14-29(10-9-16(17)11-19)35(32,33)20-7-8-20/h2-6,11-13,20H,7-10,14H2,1H3,(H2,24,30,31)(H2,25,26,27,28)	LJKOQMVQRHCBML-UHFFFAOYSA-N	397292	US9987276, Compound I-10::US10596172, Compound I-10::US10828300, Compound I-10::US11351168, Compound I-10	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397292	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397292&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44593978	405267357							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793934	Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1ccc2CN(CCc2c1)C(=O)CCl	InChI=1S/C22H23ClN6O3S/c1-14-12-25-22(27-17-3-2-4-19(10-17)33(24,31)32)28-21(14)26-18-6-5-16-13-29(20(30)11-23)8-7-15(16)9-18/h2-6,9-10,12H,7-8,11,13H2,1H3,(H2,24,31,32)(H2,25,26,27,28)	PLUJQIOUOXACEJ-UHFFFAOYSA-N	397293	US9987276, Compound I-11::US10596172, Compound I-11::US10828300, Compound I-11::US11351168, Compound I-11	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397293	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397293&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44593979	405267358							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793935	Cc1cnc(Nc2cccc(NC(=O)C=C)c2)nc1Nc1ccc(Oc2ccccc2)cc1	InChI=1S/C26H23N5O2/c1-3-24(32)28-20-8-7-9-21(16-20)30-26-27-17-18(2)25(31-26)29-19-12-14-23(15-13-19)33-22-10-5-4-6-11-22/h3-17H,1H2,2H3,(H,28,32)(H2,27,29,30,31)	RFBXRPQFQIGZCL-UHFFFAOYSA-N	397294	US9987276, Compound I-23::US10596172, Compound I-23::US10828300, Compound I-23::US11351168, Compound I-23	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397294&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594259	405267359							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793936	Cc1cnc(Nc2ccccc2)nc1NC1CCCN(C1)C(=O)C=C	InChI=1S/C19H23N5O/c1-3-17(25)24-11-7-10-16(13-24)21-18-14(2)12-20-19(23-18)22-15-8-5-4-6-9-15/h3-6,8-9,12,16H,1,7,10-11,13H2,2H3,(H2,20,21,22,23)	UOJJIRQZYSCCEU-UHFFFAOYSA-N	397146	US9987276, Compound I-27::US10596172, Compound I-27::US10828300, Compound I-27::US11351168, Compound I-27	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397146	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397146&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594263	405267214							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793937	Fc1cnc(Nc2ccccc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C19H16FN5O/c1-2-17(26)22-14-9-6-10-15(11-14)23-18-16(20)12-21-19(25-18)24-13-7-4-3-5-8-13/h2-12H,1H2,(H,22,26)(H2,21,23,24,25)	AIYAKMHAHYNWEB-UHFFFAOYSA-N	397147	US9987276, Compound I-28::US10596172, Compound I-28::US10828300, Compound I-28::US11351168, Compound I-28	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397147&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594403	405267215							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793938	Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C20H20N6O3S/c1-3-18(27)23-14-6-4-7-15(10-14)24-19-13(2)12-22-20(26-19)25-16-8-5-9-17(11-16)30(21,28)29/h3-12H,1H2,2H3,(H,23,27)(H2,21,28,29)(H2,22,24,25,26)	GBBOTMNQSLLOPI-UHFFFAOYSA-N	397148	US9987276, Compound I-33::US10596172, Compound I-33::US10828300, Compound I-33::US11351168, Compound I-33	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397148	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397148&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594407	405267216							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793939	CN(c1cccc(NC(=O)C=C)c1)c1nc(Nc2ccccc2)ncc1C	InChI=1S/C21H21N5O/c1-4-19(27)23-17-11-8-12-18(13-17)26(3)20-15(2)14-22-21(25-20)24-16-9-6-5-7-10-16/h4-14H,1H2,2-3H3,(H,23,27)(H,22,24,25)	TUZKCSVRJPNLQM-UHFFFAOYSA-N	397295	US9987276, Compound I-34::US10596172, Compound I-34::US10828300, Compound I-34::US11351168, Compound I-34	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397295	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397295&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594548	405267360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793940	Cc1cnc(Nc2cccc(OCC#C)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C23H21N5O2/c1-4-12-30-20-11-7-10-19(14-20)27-23-24-15-16(3)22(28-23)26-18-9-6-8-17(13-18)25-21(29)5-2/h1,5-11,13-15H,2,12H2,3H3,(H,25,29)(H2,24,26,27,28)	UXHFWCLHWKJMNI-UHFFFAOYSA-N	397149	US9987276, Compound I-35::US10596172, Compound I-35::US10828300, Compound I-35::US11351168, Compound I-35	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397149	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397149&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594549	405267217							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793941	CN(C)C\C=C\C(=O)Nc1cccc(Nc2nc(Nc3ccccc3)ncc2C)c1	InChI=1S/C23H26N6O/c1-17-16-24-23(27-18-9-5-4-6-10-18)28-22(17)26-20-12-7-11-19(15-20)25-21(30)13-8-14-29(2)3/h4-13,15-16H,14H2,1-3H3,(H,25,30)(H2,24,26,27,28)	IZOQLNVGRPSGOU-UHFFFAOYSA-N	397150	US9987276, Compound I-38::US10596172, Compound I-38::US10828300, Compound I-38::US11351168, Compound I-38	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397150	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397150&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594552	405267218							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793942	Cc1cnc(Nc2ccccc2)nc1Nc1ccc(NC(=O)C=C)cc1	InChI=1S/C20H19N5O/c1-3-18(26)22-16-9-11-17(12-10-16)23-19-14(2)13-21-20(25-19)24-15-7-5-4-6-8-15/h3-13H,1H2,2H3,(H,22,26)(H2,21,23,24,25)	AGLFCZURNSZZTB-UHFFFAOYSA-N	397151	US9987276, Compound I-39::US10596172, Compound I-39::US10828300, Compound I-39::US11351168, Compound I-39	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397151	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397151&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594553	405267219							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793943	Cc1cnc(Nc2cccc(OCCCNC(=O)OC(C)(C)C)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C28H34N6O4/c1-6-24(35)31-20-10-7-11-21(16-20)32-25-19(2)18-30-26(34-25)33-22-12-8-13-23(17-22)37-15-9-14-29-27(36)38-28(3,4)5/h6-8,10-13,16-18H,1,9,14-15H2,2-5H3,(H,29,36)(H,31,35)(H2,30,32,33,34)	KNYIIZLUSZJWSL-UHFFFAOYSA-N	397153	US9987276, Compound I-45::US10596172, Compound I-45::US10828300, Compound I-45::US11351168, Compound I-45	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397153	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397153&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594697	405267221							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793944	Cc1ccc(NC(=O)C=C)cc1Nc1nccc(n1)-c1cccnc1	InChI=1S/C19H17N5O/c1-3-18(25)22-15-7-6-13(2)17(11-15)24-19-21-10-8-16(23-19)14-5-4-9-20-12-14/h3-12H,1H2,2H3,(H,22,25)(H,21,23,24)	UAMMCWFAUDYUPP-UHFFFAOYSA-N	397156	US9987276, Compound I-56::US10596172, Compound I-56::US10828300, Compound I-56::US11351168, Compound I-56	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397156	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397156&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594976	405267224							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793945	CCC(=O)Nc1cccc(Nc2nc(Nc3ccccc3)ncc2C)c1	InChI=1S/C20H21N5O/c1-3-18(26)22-16-10-7-11-17(12-16)23-19-14(2)13-21-20(25-19)24-15-8-5-4-6-9-15/h4-13H,3H2,1-2H3,(H,22,26)(H2,21,23,24,25)	IACFBEWUWSMQBL-UHFFFAOYSA-N	397296	US9987276, Compound IR-7::N-(3-(5-methyl-2-(phenylamino)pyrimidin-4-ylamino)phenyl)::US11351168, Compound IR-7	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397296	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397296&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174340	405267361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793946	Fc1cnc(Nc2ccc(O[C@H]3CCOC3)nc2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C22H21FN6O3/c1-2-19(30)26-14-4-3-5-15(10-14)27-21-18(23)12-25-22(29-21)28-16-6-7-20(24-11-16)32-17-8-9-31-13-17/h2-7,10-12,17H,1,8-9,13H2,(H,26,30)(H2,25,27,28,29)	TUHXUKDYTKWTGG-UHFFFAOYSA-N	397154	US9987276, Compound I-54::US10596172, Compound I-54::US10828300, Compound I-54::US11351168, Compound I-54	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397154	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397154&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594974	405267222							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793947	CS(=O)(=O)CCCOc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl	InChI=1S/C23H23ClFN5O4S/c1-3-21(31)27-15-6-4-7-16(12-15)28-22-19(25)14-26-23(30-22)29-17-8-9-18(24)20(13-17)34-10-5-11-35(2,32)33/h3-4,6-9,12-14H,1,5,10-11H2,2H3,(H,27,31)(H2,26,28,29,30)	IPPHYKLDCJQTJI-UHFFFAOYSA-N	397155	US9987276, Compound I-55::US10596172, Compound I-55::US10828300, Compound I-55::US11351168, Compound I-55	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397155	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397155&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594975	405267223							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793948	C\C=C\C(=O)OCc1ccc(Nc2nc(Nc3ccccc3)ncc2C)cc1	InChI=1S/C22H22N4O2/c1-3-7-20(27)28-15-17-10-12-19(13-11-17)24-21-16(2)14-23-22(26-21)25-18-8-5-4-6-9-18/h3-14H,15H2,1-2H3,(H2,23,24,25,26)	GPUFLOVAENLGMC-UHFFFAOYSA-N	397297	US9987276, Compound I-60::US10596172, Compound I-60::US10828300, Compound I-60::US11351168, Compound I-60	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397297	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397297&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595118	405267362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793949	Fc1cnc(Nc2ccc(O[C@@H]3CCOC3)nc2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C22H21FN6O3/c1-2-19(30)26-14-4-3-5-15(10-14)27-21-18(23)12-25-22(29-21)28-16-6-7-20(24-11-16)32-17-8-9-31-13-17/h2-7,10-12,17H,1,8-9,13H2,(H,26,30)(H2,25,27,28,29)	TUHXUKDYTKWTGG-UHFFFAOYSA-N	397157	US9987276, Compound I-69::US10596172, Compound I-69::US10828300, Compound I-69::US11351168, Compound I-69	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397157	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397157&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595267	405267225							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793950	Fc1cnc(Nc2ccc(OCCN3CCCC3=O)nc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C24H24FN7O3/c1-2-20(33)28-16-5-3-6-17(13-16)29-23-19(25)15-27-24(31-23)30-18-8-9-21(26-14-18)35-12-11-32-10-4-7-22(32)34/h2-3,5-6,8-9,13-15H,1,4,7,10-12H2,(H,28,33)(H2,27,29,30,31)	XCCATKZDNIWAER-UHFFFAOYSA-N	397158	US9987276, Compound I-70::US10596172, Compound I-70::US10828300, Compound I-70::US11351168, Compound I-70	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397158	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397158&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595268	405267226							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793951	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(c3)C(O)C(=C)C#N)n2)cc1	InChI=1S/C23H22FN5O3/c1-15(13-25)21(30)16-4-3-5-18(12-16)27-22-20(24)14-26-23(29-22)28-17-6-8-19(9-7-17)32-11-10-31-2/h3-9,12,14,21,30H,1,10-11H2,2H3,(H2,26,27,28,29)	WQNJHPQVUGWHAP-UHFFFAOYSA-N	397298	US9987276, Compound I-71::US10596172, Compound I-71::US10828300, Compound I-71::US11351168, Compound I-71	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397298	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397298&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595410	405267363							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793952	Fc1cnc(Nc2ccc(nc2)N2CCS(=O)(=O)CC2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C22H22FN7O3S/c1-2-20(31)26-15-4-3-5-16(12-15)27-21-18(23)14-25-22(29-21)28-17-6-7-19(24-13-17)30-8-10-34(32,33)11-9-30/h2-7,12-14H,1,8-11H2,(H,26,31)(H2,25,27,28,29)	QGZJKTGTMBPJJI-UHFFFAOYSA-N	397159	US9987276, Compound I-72::US10596172, Compound I-72::US10828300, Compound I-72::US11351168, Compound I-72	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397159	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397159&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595411	405267227							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793953	COc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl	InChI=1S/C20H17ClFN5O2/c1-3-18(28)24-12-5-4-6-13(9-12)25-19-16(22)11-23-20(27-19)26-14-7-8-15(21)17(10-14)29-2/h3-11H,1H2,2H3,(H,24,28)(H2,23,25,26,27)	RIYKJTQWZNUEMB-UHFFFAOYSA-N	397299	US9987276, Compound I-74::US10596172, Compound I-74::US10828300, Compound I-74::US11351168, Compound I-74	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397299	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397299&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595413	405267364							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793954	CN1CCC(COc2cccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)c2)CC1	InChI=1S/C26H29FN6O2/c1-3-24(34)29-19-6-4-7-20(14-19)30-25-23(27)16-28-26(32-25)31-21-8-5-9-22(15-21)35-17-18-10-12-33(2)13-11-18/h3-9,14-16,18H,1,10-13,17H2,2H3,(H,29,34)(H2,28,30,31,32)	DJXONMXFXMMVGQ-UHFFFAOYSA-N	397161	US9987276, Compound I-75::US9987276, Compound I-82::US10596172, Compound I-75::US10828300, Compound I-82::US11351168, Compound I-82	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397161	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397161&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595552	405267229							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793955	CN1CCCC(COc2cccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)c2)C1	InChI=1S/C26H29FN6O2/c1-3-24(34)29-19-8-4-9-20(13-19)30-25-23(27)15-28-26(32-25)31-21-10-5-11-22(14-21)35-17-18-7-6-12-33(2)16-18/h3-5,8-11,13-15,18H,1,6-7,12,16-17H2,2H3,(H,29,34)(H2,28,30,31,32)	UGWZEBRWDXGJIN-UHFFFAOYSA-N	397162	US9987276, Compound I-76::US9987276, Compound I-81::US10596172, Compound I-76::US10828300, Compound I-76::US11351168, Compound I-76	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397162	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397162&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595415	405267230							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793956	COCCN(C)c1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C22H24FN7O2/c1-4-20(31)26-15-6-5-7-16(12-15)27-21-18(23)14-25-22(29-21)28-17-8-9-19(24-13-17)30(2)10-11-32-3/h4-9,12-14H,1,10-11H2,2-3H3,(H,26,31)(H2,25,27,28,29)	NFSNTHIPBLRXCV-UHFFFAOYSA-N	397163	US9987276, Compound I-77::US10596172, Compound I-77::US10828300, Compound I-77::US11351168, Compound I-77	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397163	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397163&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595547	405267231							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793957	CN1CCC(COc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cn2)CC1	InChI=1S/C25H28FN7O2/c1-3-22(34)29-18-5-4-6-19(13-18)30-24-21(26)15-28-25(32-24)31-20-7-8-23(27-14-20)35-16-17-9-11-33(2)12-10-17/h3-8,13-15,17H,1,9-12,16H2,2H3,(H,29,34)(H2,28,30,31,32)	BBHHILFMAQMRIE-UHFFFAOYSA-N	397164	US9987276, Compound I-78::US10596172, Compound I-78::US10828300, Compound I-78::US11351168, Compound I-78	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397164	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397164&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595548	405267232							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793958	Fc1cnc(Nc2ccc(OC3CCC3)nc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C22H21FN6O2/c1-2-19(30)26-14-5-3-6-15(11-14)27-21-18(23)13-25-22(29-21)28-16-9-10-20(24-12-16)31-17-7-4-8-17/h2-3,5-6,9-13,17H,1,4,7-8H2,(H,26,30)(H2,25,27,28,29)	XQRHDEQLYAPLAK-UHFFFAOYSA-N	397165	US9987276, Compound I-79::US10596172, Compound I-79::US10828300, Compound I-79::US11351168, Compound I-79	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397165	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397165&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595549	405267233							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793959	CS(=O)(=O)CCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C22H23FN6O4S/c1-3-19(30)26-15-6-4-7-16(12-15)27-21-18(23)14-25-22(29-21)28-17-8-9-20(24-13-17)33-10-5-11-34(2,31)32/h3-4,6-9,12-14H,1,5,10-11H2,2H3,(H,26,30)(H2,25,27,28,29)	HPNFGOZTUMHEJM-UHFFFAOYSA-N	397166	US9987276, Compound I-80::US10596172, Compound I-97::US10828300, Compound I-80::US11351168, Compound I-80	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397166	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397166&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595550	405267234							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793960	CN1CCCC(COc2cccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)c2)C1	InChI=1S/C26H29FN6O2/c1-3-24(34)29-19-8-4-9-20(13-19)30-25-23(27)15-28-26(32-25)31-21-10-5-11-22(14-21)35-17-18-7-6-12-33(2)16-18/h3-5,8-11,13-15,18H,1,6-7,12,16-17H2,2H3,(H,29,34)(H2,28,30,31,32)	UGWZEBRWDXGJIN-UHFFFAOYSA-N	397162	US9987276, Compound I-76::US9987276, Compound I-81::US10596172, Compound I-76::US10828300, Compound I-76::US11351168, Compound I-76	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397162	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397162&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595415	405267230							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793961	CN1CCC(COc2cccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)c2)CC1	InChI=1S/C26H29FN6O2/c1-3-24(34)29-19-6-4-7-20(14-19)30-25-23(27)16-28-26(32-25)31-21-8-5-9-22(15-21)35-17-18-10-12-33(2)13-11-18/h3-9,14-16,18H,1,10-13,17H2,2H3,(H,29,34)(H2,28,30,31,32)	DJXONMXFXMMVGQ-UHFFFAOYSA-N	397161	US9987276, Compound I-75::US9987276, Compound I-82::US10596172, Compound I-75::US10828300, Compound I-82::US11351168, Compound I-82	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397161	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397161&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595552	405267229							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793962	OCCN1CCN(CC1)c1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C25H28FN7O2/c1-2-23(35)28-18-5-3-6-19(15-18)29-24-22(26)17-27-25(31-24)30-20-7-4-8-21(16-20)33-11-9-32(10-12-33)13-14-34/h2-8,15-17,34H,1,9-14H2,(H,28,35)(H2,27,29,30,31)	INPLXFYOXGJFNT-UHFFFAOYSA-N	397302	US9987276, Compound I-83::US10596172, Compound I-83::US10828300, Compound I-83::US11351168, Compound I-83	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397302	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397302&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595684	405267365							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793963	OCCN1CCN(CC1)c1cccc(Nc2ncc(F)c(Oc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C25H27FN6O3/c1-2-23(34)28-19-6-4-8-21(16-19)35-24-22(26)17-27-25(30-24)29-18-5-3-7-20(15-18)32-11-9-31(10-12-32)13-14-33/h2-8,15-17,33H,1,9-14H2,(H,28,34)(H,27,29,30)	BZCWKNZYWVIXFE-UHFFFAOYSA-N	397303	US9987276, Compound I-84::US10596172, Compound I-84::US10828300, Compound I-84::US11351168, Compound I-84	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397303	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397303&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595685	405267366							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793964	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C(=C)Cn4cccn4)c3)n2)cc1	InChI=1S/C26H26FN7O3/c1-18(17-34-12-4-11-29-34)25(35)31-21-6-3-5-20(15-21)30-24-23(27)16-28-26(33-24)32-19-7-9-22(10-8-19)37-14-13-36-2/h3-12,15-16H,1,13-14,17H2,2H3,(H,31,35)(H2,28,30,32,33)	QVVBXGSHWRVSED-UHFFFAOYSA-N	397304	US9987276, Compound I-85::US10596172, Compound I-85::US10828300, Compound I-85::US11351168, Compound I-85	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397304	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397304&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595686	405267367							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793965	Fc1cnc(Nc2ccc(OCc3ccccn3)c(Cl)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C25H20ClFN6O2/c1-2-23(34)30-16-7-5-8-17(12-16)31-24-21(27)14-29-25(33-24)32-18-9-10-22(20(26)13-18)35-15-19-6-3-4-11-28-19/h2-14H,1,15H2,(H,30,34)(H2,29,31,32,33)	YOUJMWBBYDWFQN-UHFFFAOYSA-N	397305	US9987276, Compound I-86::US10596172, Compound I-86::US10828300, Compound I-86::US11351168, Compound I-86	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397305	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397305&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595687	405267368							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793966	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc(F)c(NC(=O)C=C)c3)n2)cc1	InChI=1S/C22H21F2N5O3/c1-3-20(30)28-19-12-15(6-9-17(19)23)26-21-18(24)13-25-22(29-21)27-14-4-7-16(8-5-14)32-11-10-31-2/h3-9,12-13H,1,10-11H2,2H3,(H,28,30)(H2,25,26,27,29)	ZRQFRHBERCGFFM-UHFFFAOYSA-N	397306	US9987276, Compound I-87::US10596172, Compound I-87::US10828300, Compound I-87::US11351168, Compound I-87	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397306	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397306&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595688	405267369							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793967	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)\C=C\CN4CC[C@H](O)C4)c3)n2)cc1 |r|	InChI=1S/C27H31FN6O4/c1-37-14-15-38-23-9-7-19(8-10-23)32-27-29-17-24(28)26(33-27)31-21-5-2-4-20(16-21)30-25(36)6-3-12-34-13-11-22(35)18-34/h2-10,16-17,22,35H,11-15,18H2,1H3,(H,30,36)(H2,29,31,32,33)	WXSQRASGXQJANS-UHFFFAOYSA-N	397167	US9987276, Compound I-88::US10596172, Compound I-88::US10828300, Compound I-88::US11351168, Compound I-88	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397167	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397167&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595825	405267235							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793968	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)\C=C\CN4CC[C@@H](O)C4)c3)n2)cc1 |r|	InChI=1S/C27H31FN6O4/c1-37-14-15-38-23-9-7-19(8-10-23)32-27-29-17-24(28)26(33-27)31-21-5-2-4-20(16-21)30-25(36)6-3-12-34-13-11-22(35)18-34/h2-10,16-17,22,35H,11-15,18H2,1H3,(H,30,36)(H2,29,31,32,33)	WXSQRASGXQJANS-UHFFFAOYSA-N	397168	US9987276, Compound I-89::US10596172, Compound I-89::US10828300, Compound I-89::US11351168, Compound I-89	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397168	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397168&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595826	405267236							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793969	CN1CCC(COc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc2)CC1	InChI=1S/C26H29FN6O2/c1-3-24(34)29-20-5-4-6-21(15-20)30-25-23(27)16-28-26(32-25)31-19-7-9-22(10-8-19)35-17-18-11-13-33(2)14-12-18/h3-10,15-16,18H,1,11-14,17H2,2H3,(H,29,34)(H2,28,30,31,32)	AYPVIBZTYJYHQB-UHFFFAOYSA-N	397169	US9987276, Compound I-90::US10596172, Compound I-90::US10828300, Compound I-90::US11351168, Compound I-90	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397169	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397169&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595827	405267237							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793970	CC(C)(CO)Oc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C23H24FN5O3/c1-4-20(31)26-15-7-5-8-16(11-15)27-21-19(24)13-25-22(29-21)28-17-9-6-10-18(12-17)32-23(2,3)14-30/h4-13,30H,1,14H2,2-3H3,(H,26,31)(H2,25,27,28,29)	GKTXWXUJRPJCHX-UHFFFAOYSA-N	397170	US9987276, Compound I-91::US10596172, Compound I-91::US10828300, Compound I-91::US11351168, Compound I-91	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397170	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397170&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595828	405267238							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793971	Fc1cnc(Nc2ccc(OCCN3CCCC3=O)cc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C25H25FN6O3/c1-2-22(33)28-18-5-3-6-19(15-18)29-24-21(26)16-27-25(31-24)30-17-8-10-20(11-9-17)35-14-13-32-12-4-7-23(32)34/h2-3,5-6,8-11,15-16H,1,4,7,12-14H2,(H,28,33)(H2,27,29,30,31)	JKLRFEKODOKUBD-UHFFFAOYSA-N	397307	US9987276, Compound I-92::US10596172, Compound I-92::US10828300, Compound I-92::US11351168, Compound I-92	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397307	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397307&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595829	405267370							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793972	CC(C)(CO)Oc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C23H24FN5O3/c1-4-20(31)26-16-6-5-7-17(12-16)27-21-19(24)13-25-22(29-21)28-15-8-10-18(11-9-15)32-23(2,3)14-30/h4-13,30H,1,14H2,2-3H3,(H,26,31)(H2,25,27,28,29)	SUVNJTLMINXUPA-UHFFFAOYSA-N	397308	US9987276, Compound I-93::US10596172, Compound I-93::US10828300, Compound I-93::US11351168, Compound I-93	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397308	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397308&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595975	405267371							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793973	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc4CCN(C(=O)C=C)c4c3)n2)cc1	InChI=1S/C24H24FN5O3/c1-3-22(31)30-11-10-16-4-5-18(14-21(16)30)27-23-20(25)15-26-24(29-23)28-17-6-8-19(9-7-17)33-13-12-32-2/h3-9,14-15H,1,10-13H2,2H3,(H2,26,27,28,29)	SPSAUHMKIJCTCP-UHFFFAOYSA-N	397171	US9987276, Compound I-94::US10596172, Compound I-94::US10828300, Compound I-94::US11351168, Compound I-94	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397171	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397171&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595976	405267239							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793974	COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C19H17FN6O2/c1-3-16(27)23-12-5-4-6-13(9-12)24-18-15(20)11-22-19(26-18)25-14-7-8-17(28-2)21-10-14/h3-11H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	LVQDMCXIIKGTTL-UHFFFAOYSA-N	397172	US9987276, Compound I-95::US9987276, Compound I-243::US10596172, Compound I-243::US10828300, Compound I-243::US11351168, Compound I-243	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397172	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397172&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174476	405267240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793975	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C22H21F2N5O3/c1-3-20(30)26-14-5-4-6-15(11-14)27-21-18(24)13-25-22(29-21)28-16-7-8-19(17(23)12-16)32-10-9-31-2/h3-8,11-13H,1,9-10H2,2H3,(H,26,30)(H2,25,27,28,29)	YXVOONIMMFFINO-UHFFFAOYSA-N	397173	US9987276, Compound I-96::US10596172, Compound I-96::US10828300, Compound I-96::US11351168, Compound I-96	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397173	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397173&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595977	405267241							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793976	CS(=O)(=O)CCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C23H24FN5O4S/c1-3-21(30)26-17-6-4-7-18(14-17)27-22-20(24)15-25-23(29-22)28-16-8-10-19(11-9-16)33-12-5-13-34(2,31)32/h3-4,6-11,14-15H,1,5,12-13H2,2H3,(H,26,30)(H2,25,27,28,29)	UKDRGYMUMOVHQD-UHFFFAOYSA-N	397174	US9987276, Compound I-97::US10828300, Compound I-97::US11351168, Compound I-97	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397174	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397174&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595978	405267242							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793977	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)C(=C)Cn4cccn4)c3)ncc2F)c1	InChI=1S/C24H22FN7O/c1-16-6-3-7-18(12-16)28-22-21(25)14-26-24(31-22)30-20-9-4-8-19(13-20)29-23(33)17(2)15-32-11-5-10-27-32/h3-14H,2,15H2,1H3,(H,29,33)(H2,26,28,30,31)	IGGMIWAUQDAFGD-UHFFFAOYSA-N	397309	US9987276, Compound I-98::US10596172, Compound I-98::US10828300, Compound I-98::US11351168, Compound I-98	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397309&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44595979	405267372							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793978	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)\C=C\CN4CC[C@H](O)C4)c3)ncc2F)c1 |r|	InChI=1S/C25H27FN6O2/c1-17-5-2-6-18(13-17)29-24-22(26)15-27-25(31-24)30-20-8-3-7-19(14-20)28-23(34)9-4-11-32-12-10-21(33)16-32/h2-9,13-15,21,33H,10-12,16H2,1H3,(H,28,34)(H2,27,29,30,31)	HYDYWURGLGQZJV-UHFFFAOYSA-N	397310	US9987276, Compound I-99::US10596172, Compound I-99::US10828300, Compound I-99::US11351168, Compound I-99	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397310	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397310&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174705	405267373							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793979	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)\C=C\Cn4cccn4)c3)ncc2F)c1	InChI=1S/C24H22FN7O/c1-17-6-2-7-18(14-17)29-23-21(25)16-26-24(31-23)30-20-9-3-8-19(15-20)28-22(33)10-4-12-32-13-5-11-27-32/h2-11,13-16H,12H2,1H3,(H,28,33)(H2,26,29,30,31)	FWIYWUHLQNOKBL-UHFFFAOYSA-N	397311	US9987276, Compound I-100::US10596172, Compound I-100::US10828300, Compound I-100::US11351168, Compound I-100	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397311	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397311&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174501	405267374							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793980	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)\C=C\CN4CC5CC4CN5)c3)ncc2F)c1	InChI=1S/C26H28FN7O/c1-17-5-2-6-18(11-17)31-25-23(27)15-29-26(33-25)32-20-8-3-7-19(12-20)30-24(35)9-4-10-34-16-21-13-22(34)14-28-21/h2-9,11-12,15,21-22,28H,10,13-14,16H2,1H3,(H,30,35)(H2,29,31,32,33)	AASJSIBMAXVMRQ-UHFFFAOYSA-N	397312	US9987276, Compound I-101::US10596172, Compound I-101::US10828300, Compound I-101::US11351168, Compound I-101	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397312	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397312&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174378	405267375							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793981	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)\C=C\CN4CCOCC4)c3)ncc2F)c1	InChI=1S/C25H27FN6O2/c1-18-5-2-6-19(15-18)29-24-22(26)17-27-25(31-24)30-21-8-3-7-20(16-21)28-23(33)9-4-10-32-11-13-34-14-12-32/h2-9,15-17H,10-14H2,1H3,(H,28,33)(H2,27,29,30,31)	RRMYZESHMBJYMV-UHFFFAOYSA-N	397313	US9987276, Compound I-102::US10596172, Compound I-102::US10828300, Compound I-102::US11351168, Compound I-102	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397313	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397313&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174757	405267376							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793982	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C21H21FN6O3/c1-3-18(29)25-14-5-4-6-15(11-14)26-20-17(22)13-24-21(28-20)27-16-7-8-19(23-12-16)31-10-9-30-2/h3-8,11-13H,1,9-10H2,2H3,(H,25,29)(H2,24,26,27,28)	GLWSNYDQJONZIV-UHFFFAOYSA-N	397175	US9987276, Compound I-103::US10596172, Compound I-103::US10828300, Compound I-103::US11351168, Compound I-103	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397175	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397175&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174309	405267243							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793983	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)\C=C\CN4CC[C@@H](O)C4)c3)ncc2F)c1 |r|	InChI=1S/C25H27FN6O2/c1-17-5-2-6-18(13-17)29-24-22(26)15-27-25(31-24)30-20-8-3-7-19(14-20)28-23(34)9-4-11-32-12-10-21(33)16-32/h2-9,13-15,21,33H,10-12,16H2,1H3,(H,28,34)(H2,27,29,30,31)	HYDYWURGLGQZJV-UHFFFAOYSA-N	397314	US9987276, Compound I-104::US10596172, Compound I-104::US10828300, Compound I-104::US11351168, Compound I-104	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397314	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397314&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174618	405267377							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793984	OCCOc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C21H20FN5O3/c1-2-19(29)24-14-5-3-6-15(11-14)25-20-18(22)13-23-21(27-20)26-16-7-4-8-17(12-16)30-10-9-28/h2-8,11-13,28H,1,9-10H2,(H,24,29)(H2,23,25,26,27)	VNDKDRXYEXEKGQ-UHFFFAOYSA-N	397176	US9987276, Compound I-105::US10596172, Compound I-105::US10828300, Compound I-105::US11351168, Compound I-105	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397176	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397176&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174443	405267244							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793985	Fc1cnc(Nc2ccc3CN(Cc3c2)C(=O)C=C)nc1Nc1cccc(c1)C#N	InChI=1S/C22H17FN6O/c1-2-20(30)29-12-15-6-7-18(9-16(15)13-29)27-22-25-11-19(23)21(28-22)26-17-5-3-4-14(8-17)10-24/h2-9,11H,1,12-13H2,(H2,25,26,27,28)	TXIXXVFUKKCMPT-UHFFFAOYSA-N	397315	US9987276, Compound I-106::US10596172, Compound I-106::US10828300, Compound I-106::US11351168, Compound I-106	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397315	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397315&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174697	405267378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793986	CC(C)Oc1ccc(Nc2ncc(F)c(Nc3ccc(Cl)c(NC(=O)C=C)c3)n2)cn1	InChI=1S/C21H20ClFN6O2/c1-4-18(30)28-17-9-13(5-7-15(17)22)26-20-16(23)11-25-21(29-20)27-14-6-8-19(24-10-14)31-12(2)3/h4-12H,1H2,2-3H3,(H,28,30)(H2,25,26,27,29)	NOLICVAHTJLNPB-UHFFFAOYSA-N	397177	US9987276, Compound I-107::US10596172, Compound I-107::US10828300, Compound I-107::US11351168, Compound I-107	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397177	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397177&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174564	405267245							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793987	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc(Cl)c(NC(=O)C=C)c3)n2)cc1	InChI=1S/C22H21ClFN5O3/c1-3-20(30)28-19-12-15(6-9-17(19)23)26-21-18(24)13-25-22(29-21)27-14-4-7-16(8-5-14)32-11-10-31-2/h3-9,12-13H,1,10-11H2,2H3,(H,28,30)(H2,25,26,27,29)	DPQGUVILZRVONN-UHFFFAOYSA-N	397178	US9987276, Compound I-108::US10596172, Compound I-108::US10828300, Compound I-108::US11351168, Compound I-108	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397178	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397178&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174385	405267246							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793988	COCCOc1ccc(Nc2ncc(C#N)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C23H22N6O3/c1-3-21(30)26-18-5-4-6-19(13-18)27-22-16(14-24)15-25-23(29-22)28-17-7-9-20(10-8-17)32-12-11-31-2/h3-10,13,15H,1,11-12H2,2H3,(H,26,30)(H2,25,27,28,29)	SFGUPOSNKVSOGZ-UHFFFAOYSA-N	397316	US9987276, Compound I-109::US10596172, Compound I-109::US10828300, Compound I-109::US11351168, Compound I-109	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397316	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397316&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174371	405267379							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793989	Fc1cnc(Nc2cccc(OCC(=O)N3CCOCC3)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C25H25FN6O4/c1-2-22(33)28-17-5-3-6-18(13-17)29-24-21(26)15-27-25(31-24)30-19-7-4-8-20(14-19)36-16-23(34)32-9-11-35-12-10-32/h2-8,13-15H,1,9-12,16H2,(H,28,33)(H2,27,29,30,31)	XZRLUFDHKLBOSM-UHFFFAOYSA-N	397179	US9987276, Compound I-110::US10596172, Compound I-110::US10828300, Compound I-110::US11351168, Compound I-110	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397179	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397179&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174403	405267247							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793990	CN(Cc1ccc(Oc2nc(Nc3cccc(OCCCN4CCCC4=O)c3)ncc2F)cc1)C(=O)C=C	InChI=1S/C28H30FN5O4/c1-3-25(35)33(2)19-20-10-12-22(13-11-20)38-27-24(29)18-30-28(32-27)31-21-7-4-8-23(17-21)37-16-6-15-34-14-5-9-26(34)36/h3-4,7-8,10-13,17-18H,1,5-6,9,14-16,19H2,2H3,(H,30,31,32)	YMQJXVSXBRCXQT-UHFFFAOYSA-N	397317	US9987276, Compound I-111::US10596172, Compound I-111::US10828300, Compound I-111::US11351168, Compound I-111	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397317	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397317&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174354	405267380							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793991	CC(=O)N1CCOc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc12	InChI=1S/C23H21FN6O3/c1-3-21(32)26-15-5-4-6-16(11-15)27-22-18(24)13-25-23(29-22)28-17-7-8-20-19(12-17)30(14(2)31)9-10-33-20/h3-8,11-13H,1,9-10H2,2H3,(H,26,32)(H2,25,27,28,29)	DGFXVKWMZDUVJC-UHFFFAOYSA-N	397318	US9987276, Compound I-112::US10596172, Compound I-112::US10828300, Compound I-112::US11351168, Compound I-112	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397318	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397318&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174604	405267381							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793992	COc1cccc(Nc2ncc(F)c(Nc3ccc(CN(C)C(=O)C=C)cc3)n2)c1	InChI=1S/C22H22FN5O2/c1-4-20(29)28(2)14-15-8-10-16(11-9-15)25-21-19(23)13-24-22(27-21)26-17-6-5-7-18(12-17)30-3/h4-13H,1,14H2,2-3H3,(H2,24,25,26,27)	FQZLYSOIULLZTH-UHFFFAOYSA-N	397319	US9987276, Compound I-113::US10596172, Compound I-113::US10828300, Compound I-113::US11351168, Compound I-113	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397319	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397319&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174401	405267382							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793993	COc1ccc(Nc2ncc(F)c(Nc3ccc(CN(C)C(=O)C=C)cc3)n2)cn1	InChI=1S/C21H21FN6O2/c1-4-19(29)28(2)13-14-5-7-15(8-6-14)25-20-17(22)12-24-21(27-20)26-16-9-10-18(30-3)23-11-16/h4-12H,1,13H2,2-3H3,(H2,24,25,26,27)	ORNPRGFDPUFYNM-UHFFFAOYSA-N	397180	US9987276, Compound I-114::US10596172, Compound I-114::US10828300, Compound I-114::US11351168, Compound I-114	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397180	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397180&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174299	405267248							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793994	COc1cccc(Nc2ncc(F)c(Nc3cccc(CN(C)C(=O)C=C)c3)n2)c1	InChI=1S/C22H22FN5O2/c1-4-20(29)28(2)14-15-7-5-8-16(11-15)25-21-19(23)13-24-22(27-21)26-17-9-6-10-18(12-17)30-3/h4-13H,1,14H2,2-3H3,(H2,24,25,26,27)	XVKNYUHVQXADAD-UHFFFAOYSA-N	397320	US9987276, Compound I-115::US10596172, Compound I-115::US10828300, Compound I-115::US11351168, Compound I-115	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397320	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397320&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174576	405267383							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793995	CS(=O)(=O)CCCOc1cccc(Nc2ncc(F)c(Oc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C23H23FN4O5S/c1-3-21(29)26-16-7-5-10-19(14-16)33-22-20(24)15-25-23(28-22)27-17-8-4-9-18(13-17)32-11-6-12-34(2,30)31/h3-5,7-10,13-15H,1,6,11-12H2,2H3,(H,26,29)(H,25,27,28)	IGUOAKJBIDHVRK-UHFFFAOYSA-N	397181	US9987276, Compound I-116::US11351168, Compound I-116	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397181	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397181&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174547	405267249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793996	COc1ccc(Nc2ncc(F)c(Oc3ccc(CN(C)C(=O)C=C)cc3)n2)cn1	InChI=1S/C21H20FN5O3/c1-4-19(28)27(2)13-14-5-8-16(9-6-14)30-20-17(22)12-24-21(26-20)25-15-7-10-18(29-3)23-11-15/h4-12H,1,13H2,2-3H3,(H,24,25,26)	YLCGOORWBSZEPE-UHFFFAOYSA-N	397321	US9987276, Compound I-117::US10596172, Compound I-117::US10828300, Compound I-117::US11351168, Compound I-117	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397321	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397321&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174648	405267384							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793997	CC(C)(O)COc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C23H24FN5O3/c1-4-20(30)26-15-7-5-8-16(11-15)27-21-19(24)13-25-22(29-21)28-17-9-6-10-18(12-17)32-14-23(2,3)31/h4-13,31H,1,14H2,2-3H3,(H,26,30)(H2,25,27,28,29)	JDXHHQVVORDEDG-UHFFFAOYSA-N	397182	US9987276, Compound I-118::US10596172, Compound I-118::US10828300, Compound I-118::US11351168, Compound I-118	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397182	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397182&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174518	405267250							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793998	C[C@H]1CN(C\C=C\C(=O)Nc2cccc(Nc3ncc(F)c(Nc4cccc(C)c4)n3)c2)C[C@@H](C)N1 |r|	InChI=1S/C27H32FN7O/c1-18-7-4-8-21(13-18)32-26-24(28)15-29-27(34-26)33-23-10-5-9-22(14-23)31-25(36)11-6-12-35-16-19(2)30-20(3)17-35/h4-11,13-15,19-20,30H,12,16-17H2,1-3H3,(H,31,36)(H2,29,32,33,34)	HOEYLZFJOHDJKY-UHFFFAOYSA-N	397322	US9987276, Compound I-119::US10596172, Compound I-119::US10828300, Compound I-119::US11351168, Compound I-119	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397322	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397322&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174495	405267385							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
793999	COCCN(C)C\C=C\C(=O)Nc1cccc(Nc2ncc(F)c(Nc3cccc(C)c3)n2)c1	InChI=1S/C25H29FN6O2/c1-18-7-4-8-19(15-18)29-24-22(26)17-27-25(31-24)30-21-10-5-9-20(16-21)28-23(33)11-6-12-32(2)13-14-34-3/h4-11,15-17H,12-14H2,1-3H3,(H,28,33)(H2,27,29,30,31)	LWOFHHATSQPESJ-UHFFFAOYSA-N	397323	US9987276, Compound I-120::US10596172, Compound I-120::US10828300, Compound I-120::US11351168, Compound I-120	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397323	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397323&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174337	405267386							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794000	CC(=O)c1cnc(Nc2ccc(OCCO)nc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C22H22N6O4/c1-3-19(31)25-15-5-4-6-16(11-15)26-21-18(14(2)30)13-24-22(28-21)27-17-7-8-20(23-12-17)32-10-9-29/h3-8,11-13,29H,1,9-10H2,2H3,(H,25,31)(H2,24,26,27,28)	PTGSWNLZKXRSQQ-UHFFFAOYSA-N	397183	US9987276, Compound I-121::US10596172, Compound I-121::US10828300, Compound I-121::US11351168, Compound I-121	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397183	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397183&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174686	405267251							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794001	COCCOc1ccc(Nc2ncc(C(C)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C23H24N6O4/c1-4-20(31)26-16-6-5-7-17(12-16)27-22-19(15(2)30)14-25-23(29-22)28-18-8-9-21(24-13-18)33-11-10-32-3/h4-9,12-14H,1,10-11H2,2-3H3,(H,26,31)(H2,25,27,28,29)	GKDYIIFCPMGRHA-UHFFFAOYSA-N	397184	US9987276, Compound I-122::US10596172, Compound I-122::US10828300, Compound I-122::US11351168, Compound I-122	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397184	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397184&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174498	405267252							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794002	Cc1cccc(Nc2nc(Nc3cccc(NC(=O)\C=C\CN4CCC4)c3)ncc2F)c1	InChI=1S/C24H25FN6O/c1-17-6-2-7-18(14-17)28-23-21(25)16-26-24(30-23)29-20-9-3-8-19(15-20)27-22(32)10-4-11-31-12-5-13-31/h2-4,6-10,14-16H,5,11-13H2,1H3,(H,27,32)(H2,26,28,29,30)	BAEQIJVNSGPPLR-UHFFFAOYSA-N	397324	US9987276, Compound I-123::US10596172, Compound I-123::US10828300, Compound I-123::US11351168, Compound I-123	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397324	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397324&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174545	405267387							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794003	COCCOc1ccc(Nc2ncc(C(C)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C24H25N5O4/c1-4-22(31)26-18-6-5-7-19(14-18)27-23-21(16(2)30)15-25-24(29-23)28-17-8-10-20(11-9-17)33-13-12-32-3/h4-11,14-15H,1,12-13H2,2-3H3,(H,26,31)(H2,25,27,28,29)	VVMGMLRVJMNXAO-UHFFFAOYSA-N	397185	US9987276, Compound I-124::US10596172, Compound I-124::US10828300, Compound I-124::US11351168, Compound I-124	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397185	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397185&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174360	405267253							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794004	COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)\C=C\CN(C)C)c3)n2)cn1	InChI=1S/C22H24FN7O2/c1-30(2)11-5-8-19(31)26-15-6-4-7-16(12-15)27-21-18(23)14-25-22(29-21)28-17-9-10-20(32-3)24-13-17/h4-10,12-14H,11H2,1-3H3,(H,26,31)(H2,25,27,28,29)	YFEVDBXDHAETML-UHFFFAOYSA-N	397189	US9987276, Compound I-125::US10596172, Compound I-125::US10828300, Compound I-125::US11351168, Compound I-125	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397189	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397189&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174584	405267257							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794005	CN1CCOc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc12	InChI=1S/C22H21FN6O2/c1-3-20(30)25-14-5-4-6-15(11-14)26-21-17(23)13-24-22(28-21)27-16-7-8-19-18(12-16)29(2)9-10-31-19/h3-8,11-13H,1,9-10H2,2H3,(H,25,30)(H2,24,26,27,28)	OOPSGLUITPSZOK-UHFFFAOYSA-N	397190	US9987276, Compound I-126::US10596172, Compound I-126::US10828300, Compound I-126::US11351168, Compound I-126	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397190	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397190&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174374	405267258							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794006	CN(c1cccc(NC(=O)C=C)c1)c1nc(Nc2ccc3OCCN(C)c3c2)ncc1F	InChI=1S/C23H23FN6O2/c1-4-21(31)26-15-6-5-7-17(12-15)30(3)22-18(24)14-25-23(28-22)27-16-8-9-20-19(13-16)29(2)10-11-32-20/h4-9,12-14H,1,10-11H2,2-3H3,(H,26,31)(H,25,27,28)	GKWMJVQUCWXTHE-UHFFFAOYSA-N	397325	US9987276, Compound I-127::US10596172, Compound I-127::US10828300, Compound I-127::US11351168, Compound I-127	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397325	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397325&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174438	405267388							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794007	CC(=O)c1cnc(Nc2ccc(OCCO)nc2)nc1Nc1ccc2OCCN(C(=O)C=C)c2c1	InChI=1S/C24H24N6O5/c1-3-22(33)30-8-10-34-20-6-4-16(12-19(20)30)27-23-18(15(2)32)14-26-24(29-23)28-17-5-7-21(25-13-17)35-11-9-31/h3-7,12-14,31H,1,8-11H2,2H3,(H2,26,27,28,29)	BFVOWUMSASLJQP-UHFFFAOYSA-N	397191	US9987276, Compound I-128::US10596172, Compound I-128::US10828300, Compound I-128::US11351168, Compound I-128	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397191	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397191&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174766	405267259							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794008	CC(=O)c1cnc(Nc2ccc3NC(=O)Cc3c2)nc1Nc1ccc2OCCN(C(=O)C=C)c2c1	InChI=1S/C25H22N6O4/c1-3-23(34)31-8-9-35-21-7-5-17(12-20(21)31)27-24-18(14(2)32)13-26-25(30-24)28-16-4-6-19-15(10-16)11-22(33)29-19/h3-7,10,12-13H,1,8-9,11H2,2H3,(H,29,33)(H2,26,27,28,30)	MKNSDDKFUILNBI-UHFFFAOYSA-N	397192	US9987276, Compound I-129::US10596172, Compound I-129::US10828300, Compound I-129::US11351168, Compound I-129	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397192	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397192&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174559	405267260							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794009	Fc1cnc(Nc2ccc3OCCN(C(=O)C=C)c3c2)nc1Nc1ccc2NC(=O)Cc2c1	InChI=1S/C23H19FN6O3/c1-2-21(32)30-7-8-33-19-6-4-15(11-18(19)30)27-23-25-12-16(24)22(29-23)26-14-3-5-17-13(9-14)10-20(31)28-17/h2-6,9,11-12H,1,7-8,10H2,(H,28,31)(H2,25,26,27,29)	UFXCOUMBCYZPQN-UHFFFAOYSA-N	397326	US9987276, Compound I-130::US10596172, Compound I-130::US10828300, Compound I-130::US11351168, Compound I-130	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397326	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397326&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174453	405267389							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794010	COCCOc1ccc(Nc2ncc(C3CC3)c(Oc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C25H26N4O4/c1-3-23(30)27-19-5-4-6-21(15-19)33-24-22(17-7-8-17)16-26-25(29-24)28-18-9-11-20(12-10-18)32-14-13-31-2/h3-6,9-12,15-17H,1,7-8,13-14H2,2H3,(H,27,30)(H,26,28,29)	YXOFPAPRVJJCKX-UHFFFAOYSA-N	397193	US9987276, Compound I-131::US10596172, Compound I-131::US10828300, Compound I-131::US11351168, Compound I-131	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397193	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397193&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174304	405267261							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794011	COc1cccc(Nc2ncc(c(Nc3ccc4CN(Cc4c3)C(=O)C=C)n2)C(F)(F)F)c1	InChI=1S/C23H20F3N5O2/c1-3-20(32)31-12-14-7-8-17(9-15(14)13-31)28-21-19(23(24,25)26)11-27-22(30-21)29-16-5-4-6-18(10-16)33-2/h3-11H,1,12-13H2,2H3,(H2,27,28,29,30)	XRMYEWRTHGYLGR-UHFFFAOYSA-N	397327	US9987276, Compound I-132::US10596172, Compound I-132::US10828300, Compound I-132::US11351168, Compound I-132	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397327	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397327&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174328	405267390							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794012	COc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc(OC)c1OC	InChI=1S/C22H22FN5O4/c1-5-19(29)25-13-7-6-8-14(9-13)26-21-16(23)12-24-22(28-21)27-15-10-17(30-2)20(32-4)18(11-15)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	TXKPRWDWZFXCOI-UHFFFAOYSA-N	397194	US9987276, Compound I-133::US9987276, Compound I-148::US10596172, Compound I-133::US10828300, Compound I-133::US11351168, Compound I-133	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397194	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397194&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174366	405267262							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794013	COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1OC	InChI=1S/C21H20FN5O3/c1-4-19(28)24-13-6-5-7-14(10-13)25-20-16(22)12-23-21(27-20)26-15-8-9-17(29-2)18(11-15)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)	JPZSBNNZGWBSEB-UHFFFAOYSA-N	397195	US9987276, Compound I-134::US10596172, Compound I-134::US10828300, Compound I-134::US11351168, Compound I-134	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397195	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397195&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174513	405267263							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794014	Fc1cnc(Nc2cccc(OCCN3CCOCC3)c2)nc1N[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C24H31FN6O3/c1-2-22(32)31-8-4-6-19(17-31)27-23-21(25)16-26-24(29-23)28-18-5-3-7-20(15-18)34-14-11-30-9-12-33-13-10-30/h2-3,5,7,15-16,19H,1,4,6,8-14,17H2,(H2,26,27,28,29)	XCWNPLBYOKTWMD-UHFFFAOYSA-N	397196	US9987276, Compound I-135::US10596172, Compound I-135::US10828300, Compound I-135::US11351168, Compound I-135	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397196	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397196&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174379	405267264							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794015	CN(Cc1ccc(Oc2nc(Nc3cccc(OCCCS(C)(=O)=O)c3)ncc2F)cc1)C(=O)C=C	InChI=1S/C25H27FN4O5S/c1-4-23(31)30(2)17-18-9-11-20(12-10-18)35-24-22(26)16-27-25(29-24)28-19-7-5-8-21(15-19)34-13-6-14-36(3,32)33/h4-5,7-12,15-16H,1,6,13-14,17H2,2-3H3,(H,27,28,29)	GYYCIIFVPMCQNS-UHFFFAOYSA-N	397328	US9987276, Compound I-136::US10596172, Compound I-136::US10828300, Compound I-136::US11351168, Compound I-136	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397328	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397328&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174707	405267391							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794016	COc1cccc(Nc2ncc(F)c(S[C@@H]3CCCN(C3)C(=O)C=C)n2)c1 |r|	InChI=1S/C19H21FN4O2S/c1-3-17(25)24-9-5-8-15(12-24)27-18-16(20)11-21-19(23-18)22-13-6-4-7-14(10-13)26-2/h3-4,6-7,10-11,15H,1,5,8-9,12H2,2H3,(H,21,22,23)	DMABSCFEOYNSAU-UHFFFAOYSA-N	397329	US9987276, Compound I-137::US10596172, Compound I-137::US10828300, Compound I-137::US11351168, Compound I-137	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397329	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397329&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174286	405267392							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794017	CS(=O)(=O)CCCOc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C23H24FN5O4S/c1-3-21(30)26-16-7-4-8-17(13-16)27-22-20(24)15-25-23(29-22)28-18-9-5-10-19(14-18)33-11-6-12-34(2,31)32/h3-5,7-10,13-15H,1,6,11-12H2,2H3,(H,26,30)(H2,25,27,28,29)	GFHRYXHUBXMQGZ-UHFFFAOYSA-N	397197	US9987276, Compound I-138::US10596172, Compound I-138::US10828300, Compound I-138::US11351168, Compound I-138	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397197	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397197&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174628	405267265							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794018	COCCOc1ccc(Nc2ncc(C3CC3)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C25H27N5O3/c1-3-23(31)27-19-5-4-6-20(15-19)28-24-22(17-7-8-17)16-26-25(30-24)29-18-9-11-21(12-10-18)33-14-13-32-2/h3-6,9-12,15-17H,1,7-8,13-14H2,2H3,(H,27,31)(H2,26,28,29,30)	JSRAJEWDSOVBDV-UHFFFAOYSA-N	397198	US9987276, Compound I-139::US10596172, Compound I-139::US10828300, Compound I-139::US11351168, Compound I-139	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397198	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397198&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174331	405267266							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794019	CS(=O)(=O)N1CCOc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc12	InChI=1S/C22H21FN6O4S/c1-3-20(30)25-14-5-4-6-15(11-14)26-21-17(23)13-24-22(28-21)27-16-7-8-19-18(12-16)29(9-10-33-19)34(2,31)32/h3-8,11-13H,1,9-10H2,2H3,(H,25,30)(H2,24,26,27,28)	ZCFSNHMNBOIKFS-UHFFFAOYSA-N	397199	US9987276, Compound I-140::US10596172, Compound I-140::US10828300, Compound I-140::US11351168, Compound I-140	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397199	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397199&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174465	405267267							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794020	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc4OCCN(C(=O)C=C)c4c3)n2)cc1	InChI=1S/C24H24FN5O4/c1-3-22(31)30-10-11-34-21-9-6-17(14-20(21)30)27-23-19(25)15-26-24(29-23)28-16-4-7-18(8-5-16)33-13-12-32-2/h3-9,14-15H,1,10-13H2,2H3,(H2,26,27,28,29)	WSRGAGFXOUOMNF-UHFFFAOYSA-N	397330	US9987276, Compound I-141::US10596172, Compound I-141::US10828300, Compound I-141::US11351168, Compound I-141	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397330	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397330&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174508	405267393							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794021	CN(C(=O)C(F)(F)F)c1ccc(Nc2ncc(C(C)=O)c(Nc3ccc4OCCN(C(=O)C=C)c4c3)n2)cn1	InChI=1S/C25H22F3N7O4/c1-4-21(37)35-9-10-39-19-7-5-15(11-18(19)35)31-22-17(14(2)36)13-30-24(33-22)32-16-6-8-20(29-12-16)34(3)23(38)25(26,27)28/h4-8,11-13H,1,9-10H2,2-3H3,(H2,30,31,32,33)	JJADLSVURKFRPJ-UHFFFAOYSA-N	397200	US9987276, Compound I-142::US10596172, Compound I-142::US10828300, Compound I-142::US11351168, Compound I-142	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397200	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397200&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174334	405267268							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794022	Fc1cnc(Nc2ccc3OCCN(C(=O)C(F)(F)F)c3c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C23H18F4N6O3/c1-2-19(34)29-13-4-3-5-14(10-13)30-20-16(24)12-28-22(32-20)31-15-6-7-18-17(11-15)33(8-9-36-18)21(35)23(25,26)27/h2-7,10-12H,1,8-9H2,(H,29,34)(H2,28,30,31,32)	PCTROZXOUFGQPK-UHFFFAOYSA-N	397201	US9987276, Compound I-143::US10596172, Compound I-143::US10828300, Compound I-143::US11351168, Compound I-143	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397201	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397201&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174315	405267269							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794023	Fc1cnc(Nc2cccc(OCCCN3CCCC3=O)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C26H27FN6O3/c1-2-23(34)29-18-7-3-8-19(15-18)30-25-22(27)17-28-26(32-25)31-20-9-4-10-21(16-20)36-14-6-13-33-12-5-11-24(33)35/h2-4,7-10,15-17H,1,5-6,11-14H2,(H,29,34)(H2,28,30,31,32)	FABMEBDVFWJDKM-UHFFFAOYSA-N	397216	US9987276, Compound I-162::US9987276, Compound I-144::US10596172, Compound I-144::US10828300, Compound I-144::US11351168, Compound I-164	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397216	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174317	405267284							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794024	OCc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C20H18FN5O2/c1-2-18(28)23-15-7-4-8-16(10-15)24-19-17(21)11-22-20(26-19)25-14-6-3-5-13(9-14)12-27/h2-11,27H,1,12H2,(H,23,28)(H2,22,24,25,26)	ZUFBKQYSYRJFHL-UHFFFAOYSA-N	397332	US9987276, Compound I-145::US10596172, Compound I-145::US10828300, Compound I-145::US11351168, Compound I-145	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397332	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397332&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174452	405267394							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794025	CN(Cc1ccc(Nc2nc(Nc3cccc(OCCN4CCCC4=O)c3)ncc2F)cc1)C(=O)C=C	InChI=1S/C27H29FN6O3/c1-3-24(35)33(2)18-19-9-11-20(12-10-19)30-26-23(28)17-29-27(32-26)31-21-6-4-7-22(16-21)37-15-14-34-13-5-8-25(34)36/h3-4,6-7,9-12,16-17H,1,5,8,13-15,18H2,2H3,(H2,29,30,31,32)	BRQXWVJKMWGRCE-UHFFFAOYSA-N	397202	US9987276, Compound I-146::US10596172, Compound I-146	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397202	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397202&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122634986	405267270							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794026	Fc1cnc(Nc2cccc(Cl)c2)nc1N[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C18H19ClFN5O/c1-2-16(26)25-8-4-7-14(11-25)22-17-15(20)10-21-18(24-17)23-13-6-3-5-12(19)9-13/h2-3,5-6,9-10,14H,1,4,7-8,11H2,(H2,21,22,23,24)	WFICTHAFEPOCDF-UHFFFAOYSA-N	397203	US9987276, Compound I-147::US10596172, Compound I-147::US10828300, Compound I-147::US11351168, Compound I-147	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397203	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397203&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174459	405267271							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794027	COc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc(OC)c1OC	InChI=1S/C22H22FN5O4/c1-5-19(29)25-13-7-6-8-14(9-13)26-21-16(23)12-24-22(28-21)27-15-10-17(30-2)20(32-4)18(11-15)31-3/h5-12H,1H2,2-4H3,(H,25,29)(H2,24,26,27,28)	TXKPRWDWZFXCOI-UHFFFAOYSA-N	397194	US9987276, Compound I-133::US9987276, Compound I-148::US10596172, Compound I-133::US10828300, Compound I-133::US11351168, Compound I-133	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397194	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397194&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174366	405267262							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794028	Fc1cnc(Nc2ccc3OCCC(C(=O)C=C)c3c2)nc1Nc1cccc(Cl)c1	InChI=1S/C22H18ClFN4O2/c1-2-19(29)16-8-9-30-20-7-6-15(11-17(16)20)27-22-25-12-18(24)21(28-22)26-14-5-3-4-13(23)10-14/h2-7,10-12,16H,1,8-9H2,(H2,25,26,27,28)	DXSRDQDLJYOXOL-UHFFFAOYSA-N	397204	US9987276, Compound I-149	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397204	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397204&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122634987	405267272							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794029	COCCOc1ccc(Nc2ncc(C(C)=O)c(Nc3ccc4OCCN(C(=O)C=C)c4c3)n2)cc1	InChI=1S/C26H27N5O5/c1-4-24(33)31-11-12-36-23-10-7-19(15-22(23)31)28-25-21(17(2)32)16-27-26(30-25)29-18-5-8-20(9-6-18)35-14-13-34-3/h4-10,15-16H,1,11-14H2,2-3H3,(H2,27,28,29,30)	AWKHJTFBGORTJN-UHFFFAOYSA-N	397205	US9987276, Compound I-150::US10596172, Compound I-150::US10828300, Compound I-150::US11351168, Compound I-150	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397205	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397205&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174461	405267273							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794030	CC(C)(C)OC(=O)n1ncc2cc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)ccc12	InChI=1S/C25H24FN7O3/c1-5-21(34)29-16-7-6-8-17(12-16)30-22-19(26)14-27-23(32-22)31-18-9-10-20-15(11-18)13-28-33(20)24(35)36-25(2,3)4/h5-14H,1H2,2-4H3,(H,29,34)(H2,27,30,31,32)	UNPGABFQHYGLOJ-UHFFFAOYSA-N	397206	US9987276, Compound I-151::US10596172, Compound I-151::US10828300, Compound I-151::US11351168, Compound I-151	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397206	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397206&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174327	405267274							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794031	CC(=O)c1cnc(Nc2ccc(cc2)N2CCCC2=O)nc1Nc1ccc2OCCN(C(=O)C=C)c2c1	InChI=1S/C27H26N6O4/c1-3-24(35)33-13-14-37-23-11-8-19(15-22(23)33)29-26-21(17(2)34)16-28-27(31-26)30-18-6-9-20(10-7-18)32-12-4-5-25(32)36/h3,6-11,15-16H,1,4-5,12-14H2,2H3,(H2,28,29,30,31)	PFDRMUBURSHXNT-UHFFFAOYSA-N	397207	US9987276, Compound I-152::US10596172, Compound I-152::US10828300, Compound I-152::US11351168, Compound I-152	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397207	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397207&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174627	405267275							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794032	CC(=O)c1cnc(Nc2ccc3[nH]ncc3c2)nc1Nc1ccc2OCCN(C(=O)C=C)c2c1	InChI=1S/C24H21N7O3/c1-3-22(33)31-8-9-34-21-7-5-17(11-20(21)31)27-23-18(14(2)32)13-25-24(29-23)28-16-4-6-19-15(10-16)12-26-30-19/h3-7,10-13H,1,8-9H2,2H3,(H,26,30)(H2,25,27,28,29)	HTLMUUOVDLGGGH-UHFFFAOYSA-N	397208	US9987276, Compound I-153::US10596172, Compound I-153::US10828300, Compound I-153::US11351168, Compound I-153	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397208	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397208&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174669	405267276							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794033	CC(=O)c1cnc(Nc2ccc3n(C)ncc3c2)nc1Nc1ccc2OCCN(C(=O)C=C)c2c1	InChI=1S/C25H23N7O3/c1-4-23(34)32-9-10-35-22-8-6-18(12-21(22)32)28-24-19(15(2)33)14-26-25(30-24)29-17-5-7-20-16(11-17)13-27-31(20)3/h4-8,11-14H,1,9-10H2,2-3H3,(H2,26,28,29,30)	LOBTXHGFOYHRAM-UHFFFAOYSA-N	397209	US9987276, Compound I-154::US10596172, Compound I-154::US10828300, Compound I-154::US11351168, Compound I-154	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397209	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397209&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174483	405267277							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794034	Cn1ncc2cc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)ccc12	InChI=1S/C21H18FN7O/c1-3-19(30)25-14-5-4-6-15(10-14)26-20-17(22)12-23-21(28-20)27-16-7-8-18-13(9-16)11-24-29(18)2/h3-12H,1H2,2H3,(H,25,30)(H2,23,26,27,28)	GURMURZEEJVYHS-UHFFFAOYSA-N	397210	US9987276, Compound I-155::US10596172, Compound I-155::US10828300, Compound I-155::US11351168, Compound I-155	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397210	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397210&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174510	405267278							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794035	Fc1cnc(Nc2ccc3[nH]ncc3c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C20H16FN7O/c1-2-18(29)24-13-4-3-5-14(9-13)25-19-16(21)11-22-20(27-19)26-15-6-7-17-12(8-15)10-23-28-17/h2-11H,1H2,(H,23,28)(H,24,29)(H2,22,25,26,27)	WZDLCZLNEODAPO-UHFFFAOYSA-N	397211	US9987276, Compound I-156::US10596172, Compound I-156::US10828300, Compound I-156::US11351168, Compound I-156	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397211	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397211&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174298	405267279							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794036	C=CC(=O)Nc1cccc(Nc2nc(Nc3ccccc3)ncc2C#N)c1	InChI=1S/C20H16N6O/c1-2-18(27)23-16-9-6-10-17(11-16)24-19-14(12-21)13-22-20(26-19)25-15-7-4-3-5-8-15/h2-11,13H,1H2,(H,23,27)(H2,22,24,25,26)	DIOMEEGYXLOHPP-UHFFFAOYSA-N	397212	US9987276, Compound I-157::US10596172, Compound I-157::US10828300, Compound I-157::US11351168, Compound I-157	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397212	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397212&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594550	405267280							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794037	COc1cccc(Nc2ncc(OC)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C21H21N5O3/c1-4-19(27)23-14-7-5-8-15(11-14)24-20-18(29-3)13-22-21(26-20)25-16-9-6-10-17(12-16)28-2/h4-13H,1H2,2-3H3,(H,23,27)(H2,22,24,25,26)	KFXNBEFHAHIVDG-UHFFFAOYSA-N	397213	US9987276, Compound I-158::US10596172, Compound I-158::US10828300, Compound I-158::US11351168, Compound I-158	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397213	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397213&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174566	405267281							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794038	COc1ccc(Nc2ncc(C(=O)Nc3ccccc3)c(Oc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C26H22N6O4/c1-3-22(33)29-18-10-7-11-20(14-18)36-25-21(24(34)30-17-8-5-4-6-9-17)16-28-26(32-25)31-19-12-13-23(35-2)27-15-19/h3-16H,1H2,2H3,(H,29,33)(H,30,34)(H,28,31,32)	UQXNPUZHVLKGIN-UHFFFAOYSA-N	397214	US9987276, Compound I-159::US10596172, Compound I-159::US10828300, Compound I-159::US11351168, Compound I-159	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397214	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397214&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174389	405267282							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794039	NS(=O)(=O)c1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C19H17FN6O3S/c1-2-17(27)23-12-5-3-6-13(9-12)24-18-16(20)11-22-19(26-18)25-14-7-4-8-15(10-14)30(21,28)29/h2-11H,1H2,(H,23,27)(H2,21,28,29)(H2,22,24,25,26)	MWTKGPZRLJFCHQ-UHFFFAOYSA-N	397215	US9987276, Compound I-160::US10596172, Compound I-160::US10828300, Compound I-160::US11351168, Compound I-160	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397215	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397215&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174399	405267283							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794040	OC(C(=C)C#N)c1ccc(Nc2nc(Nc3ccccc3)ncc2F)cc1	InChI=1S/C20H16FN5O/c1-13(11-22)18(27)14-7-9-16(10-8-14)24-19-17(21)12-23-20(26-19)25-15-5-3-2-4-6-15/h2-10,12,18,27H,1H2,(H2,23,24,25,26)	FCKRSPPTGKYSKD-UHFFFAOYSA-N	397334	US9987276, Compound I-161::US10596172, Compound I-161::US10828300, Compound I-161::US11351168, Compound I-161	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397334	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397334&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174429	405267395							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794041	Fc1cnc(Nc2cccc(OCCCN3CCCC3=O)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C26H27FN6O3/c1-2-23(34)29-18-7-3-8-19(15-18)30-25-22(27)17-28-26(32-25)31-20-9-4-10-21(16-20)36-14-6-13-33-12-5-11-24(33)35/h2-4,7-10,15-17H,1,5-6,11-14H2,(H,29,34)(H2,28,30,31,32)	FABMEBDVFWJDKM-UHFFFAOYSA-N	397216	US9987276, Compound I-162::US9987276, Compound I-144::US10596172, Compound I-144::US10828300, Compound I-144::US11351168, Compound I-164	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397216	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397216&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174317	405267284							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794042	OC(C(=C)C#N)c1cccc(Nc2nc(Nc3cccc(OC(F)(F)F)c3)ncc2F)c1	InChI=1S/C21H15F4N5O2/c1-12(10-26)18(31)13-4-2-5-14(8-13)28-19-17(22)11-27-20(30-19)29-15-6-3-7-16(9-15)32-21(23,24)25/h2-9,11,18,31H,1H2,(H2,27,28,29,30)	AEHRZOAEPAEIFE-UHFFFAOYSA-N	397217	US9987276, Compound I-163::US10596172, Compound I-163::US10828300, Compound I-163::US11351168, Compound I-163	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397217	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397217&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174398	405267285							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794043	Fc1cnc(Nc2cccc(OCCN3CCCC3=O)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C25H25FN6O3/c1-2-22(33)28-17-6-3-7-18(14-17)29-24-21(26)16-27-25(31-24)30-19-8-4-9-20(15-19)35-13-12-32-11-5-10-23(32)34/h2-4,6-9,14-16H,1,5,10-13H2,(H,28,33)(H2,27,29,30,31)	ACGSIOSESQWBFI-UHFFFAOYSA-N	397218	US9987276, Compound I-164::US9987276, Compound I-184::US10596172, Compound I-184::US10828300, Compound I-164	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397218	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397218&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174556	405267286							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794044	COc1ccc(Nc2ncc(F)c(Nc3ccc4CN(Cc4c3)C(=O)C=C)n2)cn1	InChI=1S/C21H19FN6O2/c1-3-19(29)28-11-13-4-5-15(8-14(13)12-28)25-20-17(22)10-24-21(27-20)26-16-6-7-18(30-2)23-9-16/h3-10H,1,11-12H2,2H3,(H2,24,25,26,27)	VSXGZFSCXNNZQM-UHFFFAOYSA-N	397219	US9987276, Compound I-165::US10596172, Compound I-165::US10828300, Compound I-165::US11351168, Compound I-165	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397219	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397219&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174434	405267287							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794045	COc1ccc(Nc2ncc(F)c(Nc3ccc4CCN(C(=O)C=C)c4c3)n2)cn1	InChI=1S/C21H19FN6O2/c1-3-19(29)28-9-8-13-4-5-14(10-17(13)28)25-20-16(22)12-24-21(27-20)26-15-6-7-18(30-2)23-11-15/h3-7,10-12H,1,8-9H2,2H3,(H2,24,25,26,27)	PEXAQPCFVMFFRX-UHFFFAOYSA-N	397220	US9987276, Compound I-166::US10596172, Compound I-166::US10828300, Compound I-166::US11351168, Compound I-166	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397220	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397220&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174416	405267288							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794046	COc1ccc(Nc2ncc(C3CC3)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C22H22N6O2/c1-3-19(29)25-15-5-4-6-16(11-15)26-21-18(14-7-8-14)13-24-22(28-21)27-17-9-10-20(30-2)23-12-17/h3-6,9-14H,1,7-8H2,2H3,(H,25,29)(H2,24,26,27,28)	VMGAPTFREQGMRR-UHFFFAOYSA-N	397221	US9987276, Compound I-167::US10596172, Compound I-167::US10828300, Compound I-167::US11351168, Compound I-167	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397221	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397221&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174391	405267289							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794047	CC(=O)c1cnc(Nc2ccc(nc2)N2CCOCC2)nc1Nc1ccc2OCCN(C(=O)C=C)c2c1	InChI=1S/C26H27N7O4/c1-3-24(35)33-10-13-37-22-6-4-18(14-21(22)33)29-25-20(17(2)34)16-28-26(31-25)30-19-5-7-23(27-15-19)32-8-11-36-12-9-32/h3-7,14-16H,1,8-13H2,2H3,(H2,28,29,30,31)	GOTOIOMNNUIRFX-UHFFFAOYSA-N	397222	US9987276, Compound I-168::US10596172, Compound I-168::US10828300, Compound I-168::US11351168, Compound I-168	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397222	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397222&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174305	405267290							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794048	CC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1Nc1ccc2OCCN(C(=O)C=C)c2c1	InChI=1S/C27H28N6O4/c1-3-25(35)33-12-15-37-24-9-6-20(16-23(24)33)29-26-22(18(2)34)17-28-27(31-26)30-19-4-7-21(8-5-19)32-10-13-36-14-11-32/h3-9,16-17H,1,10-15H2,2H3,(H2,28,29,30,31)	LMZDUVITRJKZFK-UHFFFAOYSA-N	397223	US9987276, Compound I-169::US10596172, Compound I-169::US10828300, Compound I-169::US11351168, Compound I-169	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397223	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397223&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174815	405267291							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794049	COc1ccc(Nc2ncc(C(C)=O)c(Nc3ccc4OCCN(C(=O)C=C)c4c3)n2)cc1	InChI=1S/C24H23N5O4/c1-4-22(31)29-11-12-33-21-10-7-17(13-20(21)29)26-23-19(15(2)30)14-25-24(28-23)27-16-5-8-18(32-3)9-6-16/h4-10,13-14H,1,11-12H2,2-3H3,(H2,25,26,27,28)	JRJCORKKASTTKD-UHFFFAOYSA-N	397224	US9987276, Compound I-170	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397224	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397224&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122634988	405267292							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794050	COc1ccc(Nc2ncc(C#N)c(n2)N(C(=O)C=C)c2cccc(NC(=O)C=C)c2)cn1	InChI=1S/C23H19N7O3/c1-4-19(31)27-16-7-6-8-18(11-16)30(21(32)5-2)22-15(12-24)13-26-23(29-22)28-17-9-10-20(33-3)25-14-17/h4-11,13-14H,1-2H2,3H3,(H,27,31)(H,26,28,29)	JQZJSVYLROQXIC-UHFFFAOYSA-N	397335	US9987276, Compound I-171::US10596172, Compound I-171::US10828300, Compound I-171::US11351168, Compound I-171	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397335	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397335&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174623	405267396							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794051	CC(C)Oc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C21H21FN6O2/c1-4-18(29)25-14-6-5-7-15(10-14)26-20-17(22)12-24-21(28-20)27-16-8-9-19(23-11-16)30-13(2)3/h4-13H,1H2,2-3H3,(H,25,29)(H2,24,26,27,28)	QCJXKESYOASOES-UHFFFAOYSA-N	397225	US9987276, Compound I-172::US10596172, Compound I-172::US10828300, Compound I-172::US11351168, Compound I-172	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397225	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397225&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174656	405267293							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794052	COc1ccc(Nc2ncc(C#N)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C20H17N7O2/c1-3-17(28)24-14-5-4-6-15(9-14)25-19-13(10-21)11-23-20(27-19)26-16-7-8-18(29-2)22-12-16/h3-9,11-12H,1H2,2H3,(H,24,28)(H2,23,25,26,27)	BCAXHRNELQKNTO-UHFFFAOYSA-N	397226	US9987276, Compound I-173::US10596172, Compound I-173::US10828300, Compound I-173::US11351168, Compound I-173	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397226	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397226&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174292	405267294							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794053	Fc1cnc(Nc2ccc3OCCNc3c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C21H19FN6O2/c1-2-19(29)25-13-4-3-5-14(10-13)26-20-16(22)12-24-21(28-20)27-15-6-7-18-17(11-15)23-8-9-30-18/h2-7,10-12,23H,1,8-9H2,(H,25,29)(H2,24,26,27,28)	XBKUZAHBOAJCHX-UHFFFAOYSA-N	397227	US9987276, Compound I-174::US10596172, Compound I-174::US10828300, Compound I-174::US11351168, Compound I-174	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397227	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397227&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174382	405267295							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794054	CC(C)(C)OC(=O)N1CCOc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc12	InChI=1S/C26H27FN6O4/c1-5-22(34)29-16-7-6-8-17(13-16)30-23-19(27)15-28-24(32-23)31-18-9-10-21-20(14-18)33(11-12-36-21)25(35)37-26(2,3)4/h5-10,13-15H,1,11-12H2,2-4H3,(H,29,34)(H2,28,30,31,32)	GJZCUDIBZGUTHL-UHFFFAOYSA-N	397336	US9987276, Compound I-175::US10596172, Compound I-175::US10828300, Compound I-175::US11351168, Compound I-175	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397336	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397336&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174424	405267397							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794055	COc1ccc(Nc2ncc(C(=O)NC3CC3)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C23H23N7O3/c1-3-19(31)26-15-5-4-6-16(11-15)27-21-18(22(32)28-14-7-8-14)13-25-23(30-21)29-17-9-10-20(33-2)24-12-17/h3-6,9-14H,1,7-8H2,2H3,(H,26,31)(H,28,32)(H2,25,27,29,30)	WRVCWRJAPOCUSC-UHFFFAOYSA-N	397228	US9987276, Compound I-176::US10596172, Compound I-176	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397228	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397228&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174427	405267296							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794056	COc1cccc(Nc2ncc(C(=O)NC3CC3)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C24H24N6O3/c1-3-21(31)26-16-6-4-7-17(12-16)27-22-20(23(32)28-15-10-11-15)14-25-24(30-22)29-18-8-5-9-19(13-18)33-2/h3-9,12-15H,1,10-11H2,2H3,(H,26,31)(H,28,32)(H2,25,27,29,30)	CIMJEKPFNXEBIR-UHFFFAOYSA-N	397229	US9987276, Compound I-177	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397229	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397229&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174681	405267297							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794057	COc1cccc(Nc2ncc(C(N)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C21H20N6O3/c1-3-18(28)24-13-6-4-7-14(10-13)25-20-17(19(22)29)12-23-21(27-20)26-15-8-5-9-16(11-15)30-2/h3-12H,1H2,2H3,(H2,22,29)(H,24,28)(H2,23,25,26,27)	YQGWYHRINGUJLC-UHFFFAOYSA-N	397230	US9987276, Compound I-178::US9987276, Compound I-210::US10596172, Compound I-210::US10828300, Compound I-210::US11351168, Compound I-210	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397230	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397230&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174418	405267298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794058	COc1cccc(Nc2ncc(F)c(OC3CCCN(C3)C(=O)C=C)n2)c1	InChI=1S/C19H21FN4O3/c1-3-17(25)24-9-5-8-15(12-24)27-18-16(20)11-21-19(23-18)22-13-6-4-7-14(10-13)26-2/h3-4,6-7,10-11,15H,1,5,8-9,12H2,2H3,(H,21,22,23)	ZIZGVHGZRPPXOW-UHFFFAOYSA-N	397337	US9987276, Compound I-179::US10596172, Compound I-179::US10828300, Compound I-179::US11351168, Compound I-179	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397337	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397337&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174558	405267398							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794059	COc1ccc(Nc2ncc(F)c(OC3CCCN(C3)C(=O)C=C)n2)cc1	InChI=1S/C19H21FN4O3/c1-3-17(25)24-10-4-5-15(12-24)27-18-16(20)11-21-19(23-18)22-13-6-8-14(26-2)9-7-13/h3,6-9,11,15H,1,4-5,10,12H2,2H3,(H,21,22,23)	VLPCHMNFTMDPSG-UHFFFAOYSA-N	397231	US9987276, Compound I-180	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397231	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397231&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122634989	405267299							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794060	Fc1cnc(Nc2ccc3NC(=O)Cc3c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C21H17FN6O2/c1-2-18(29)24-13-4-3-5-14(10-13)25-20-16(22)11-23-21(28-20)26-15-6-7-17-12(8-15)9-19(30)27-17/h2-8,10-11H,1,9H2,(H,24,29)(H,27,30)(H2,23,25,26,28)	AGFKHUQYDGJBJG-UHFFFAOYSA-N	397338	US9987276, Compound I-181::US10596172, Compound I-181::US10828300, Compound I-181::US11351168, Compound I-181	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397338	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397338&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174356	405267399							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794061	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C22H22FN5O3/c1-3-20(29)25-16-5-4-6-17(13-16)26-21-19(23)14-24-22(28-21)27-15-7-9-18(10-8-15)31-12-11-30-2/h3-10,13-14H,1,11-12H2,2H3,(H,25,29)(H2,24,26,27,28)	KXBDTLQSDKGAEB-UHFFFAOYSA-N	50161162	AVL-292::CC-292::Spebrutinib::US9987276, Compound I-182::US10596172, Compound I-182::US10828300, Compound I-182::US11351168, Compound I-182	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161162	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161162&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174488	104047556							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794062	CC(C)(C)OC(=O)NCCCOc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C27H31FN6O4/c1-5-23(35)31-18-9-6-10-19(15-18)32-24-22(28)17-30-25(34-24)33-20-11-7-12-21(16-20)37-14-8-13-29-26(36)38-27(2,3)4/h5-7,9-12,15-17H,1,8,13-14H2,2-4H3,(H,29,36)(H,31,35)(H2,30,32,33,34)	UCTPTVSGWMGCAU-UHFFFAOYSA-N	397233	US9987276, Compound I-183::US10596172, Compound I-183::US10828300, Compound I-183::US11351168, Compound I-183	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397233	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397233&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174477	405267301							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794063	Fc1cnc(Nc2cccc(OCCN3CCCC3=O)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C25H25FN6O3/c1-2-22(33)28-17-6-3-7-18(14-17)29-24-21(26)16-27-25(31-24)30-19-8-4-9-20(15-19)35-13-12-32-11-5-10-23(32)34/h2-4,6-9,14-16H,1,5,10-13H2,(H,28,33)(H2,27,29,30,31)	ACGSIOSESQWBFI-UHFFFAOYSA-N	397218	US9987276, Compound I-164::US9987276, Compound I-184::US10596172, Compound I-184::US10828300, Compound I-164	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397218	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397218&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174556	405267286							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794064	CC(=C)C(=O)c1ccc(Nc2nc(Nc3ccccc3)ncc2F)cc1	InChI=1S/C20H17FN4O/c1-13(2)18(26)14-8-10-16(11-9-14)23-19-17(21)12-22-20(25-19)24-15-6-4-3-5-7-15/h3-12H,1H2,2H3,(H2,22,23,24,25)	OQGGDZLIFOFKSA-UHFFFAOYSA-N	397234	US9987276, Compound I-185::US10596172, Compound I-185::US10828300, Compound I-185::US11351168, Compound I-185	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397234	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397234&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174746	405267302							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794065	COc1ccc(Nc2ncc(C)c(Oc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C20H19N5O3/c1-4-17(26)23-14-6-5-7-16(10-14)28-19-13(2)11-22-20(25-19)24-15-8-9-18(27-3)21-12-15/h4-12H,1H2,2-3H3,(H,23,26)(H,22,24,25)	JKXPYDYCFRBOIP-UHFFFAOYSA-N	397235	US9987276, Compound I-186::US10596172, Compound I-186::US10828300, Compound I-186::US11351168, Compound I-186	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397235	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397235&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174578	405267303							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794066	COc1ccc(Nc2ncc(C(C)=O)c(NC3CN(C3)C(=O)C=C)n2)cn1	InChI=1S/C18H20N6O3/c1-4-16(26)24-9-13(10-24)21-17-14(11(2)25)8-20-18(23-17)22-12-5-6-15(27-3)19-7-12/h4-8,13H,1,9-10H2,2-3H3,(H2,20,21,22,23)	GZRAWWJVYUECSE-UHFFFAOYSA-N	397340	US9987276, Compound I-187::US10596172, Compound I-187::US10828300, Compound I-187::US11351168, Compound I-187	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397340	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397340&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174582	405267400							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794067	COc1ccc(Nc2ncc(C(C)=O)c(Oc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C21H19N5O4/c1-4-18(28)24-14-6-5-7-16(10-14)30-20-17(13(2)27)12-23-21(26-20)25-15-8-9-19(29-3)22-11-15/h4-12H,1H2,2-3H3,(H,24,28)(H,23,25,26)	IBFHOCMFPCPAOR-UHFFFAOYSA-N	397236	US9987276, Compound I-188::US10596172, Compound I-188::US10828300, Compound I-188::US11351168, Compound I-188	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397236	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397236&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174689	405267304							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794068	COc1ccc(Nc2ncc(C(C)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C21H20N6O3/c1-4-18(29)24-14-6-5-7-15(10-14)25-20-17(13(2)28)12-23-21(27-20)26-16-8-9-19(30-3)22-11-16/h4-12H,1H2,2-3H3,(H,24,29)(H2,23,25,26,27)	IJLMNTCRBOYVAH-UHFFFAOYSA-N	397237	US9987276, Compound I-189::US9987276, Compound I-192::US10596172, Compound I-189::US10828300, Compound I-189::US11351168, Compound I-189	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397237	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397237&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174300	405267305							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794069	COc1cccc(Nc2ncc(F)c(O[C@@H]3CCCN(C3)C(=O)C=C)n2)c1 |r|	InChI=1S/C19H21FN4O3/c1-3-17(25)24-9-5-8-15(12-24)27-18-16(20)11-21-19(23-18)22-13-6-4-7-14(10-13)26-2/h3-4,6-7,10-11,15H,1,5,8-9,12H2,2H3,(H,21,22,23)	ZIZGVHGZRPPXOW-UHFFFAOYSA-N	397238	US9987276, Compound I-190::US10596172, Compound I-190::US10828300, Compound I-190::US11351168, Compound I-190	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397238	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397238&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174291	405267306							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794070	COc1ccc(Nc2ncc(F)c(OC3CCCN(C3)C(=O)C=C)n2)cn1	InChI=1S/C18H20FN5O3/c1-3-16(25)24-8-4-5-13(11-24)27-17-14(19)10-21-18(23-17)22-12-6-7-15(26-2)20-9-12/h3,6-7,9-10,13H,1,4-5,8,11H2,2H3,(H,21,22,23)	CPIVTGQSAQHKHT-UHFFFAOYSA-N	397341	US9987276, Compound I-191::US10596172, Compound I-191::US10828300, Compound I-191::US11351168, Compound I-180	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397341	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397341&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174480	405267401							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794071	COc1ccc(Nc2ncc(C(C)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C21H20N6O3/c1-4-18(29)24-14-6-5-7-15(10-14)25-20-17(13(2)28)12-23-21(27-20)26-16-8-9-19(30-3)22-11-16/h4-12H,1H2,2-3H3,(H,24,29)(H2,23,25,26,27)	IJLMNTCRBOYVAH-UHFFFAOYSA-N	397237	US9987276, Compound I-189::US9987276, Compound I-192::US10596172, Compound I-189::US10828300, Compound I-189::US11351168, Compound I-189	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397237	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397237&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174300	405267305							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794072	COc1ccc(Nc2ncc(F)c(O[C@H]3CCCN(C3)C(=O)C=C)n2)cn1 |r|	InChI=1S/C18H20FN5O3/c1-3-16(25)24-8-4-5-13(11-24)27-17-14(19)10-21-18(23-17)22-12-6-7-15(26-2)20-9-12/h3,6-7,9-10,13H,1,4-5,8,11H2,2H3,(H,21,22,23)	CPIVTGQSAQHKHT-UHFFFAOYSA-N	397342	US9987276, Compound I-193::US10596172, Compound I-193::US10828300, Compound I-193::US11351168, Compound I-193	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397342	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397342&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174587	405267402							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794073	COc1ccc(Nc2ncc(F)c(Nc3ccc4OCCN(C(=O)C=C)c4c3)n2)cn1	InChI=1S/C21H19FN6O3/c1-3-19(29)28-8-9-31-17-6-4-13(10-16(17)28)25-20-15(22)12-24-21(27-20)26-14-5-7-18(30-2)23-11-14/h3-7,10-12H,1,8-9H2,2H3,(H2,24,25,26,27)	DLWPYOMISFMFJC-UHFFFAOYSA-N	397240	US9987276, Compound I-194::US10596172, Compound I-194::US10828300, Compound I-194::US11351168, Compound I-194	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397240	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397240&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174352	405267307							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794074	COc1cccc(Nc2ncc(F)c(N[C@@H]3CCCN(C3)C(=O)C=C)n2)c1 |r|	InChI=1S/C19H22FN5O2/c1-3-17(26)25-9-5-7-14(12-25)22-18-16(20)11-21-19(24-18)23-13-6-4-8-15(10-13)27-2/h3-4,6,8,10-11,14H,1,5,7,9,12H2,2H3,(H2,21,22,23,24)	AYPKVDHLTACEBB-UHFFFAOYSA-N	397241	US9987276, Compound I-195::US10596172, Compound I-195::US10828300, Compound I-195::US11351168, Compound I-195	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397241	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397241&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174537	405267308							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794075	COc1cccc(Nc2ncc(F)c(N[C@H]3CCCN(C3)C(=O)C=C)n2)c1 |r|	InChI=1S/C19H22FN5O2/c1-3-17(26)25-9-5-7-14(12-25)22-18-16(20)11-21-19(24-18)23-13-6-4-8-15(10-13)27-2/h3-4,6,8,10-11,14H,1,5,7,9,12H2,2H3,(H2,21,22,23,24)	AYPKVDHLTACEBB-UHFFFAOYSA-N	397343	US9987276, Compound I-196::US10596172, Compound I-196::US10828300, Compound I-196::US11351168, Compound I-196	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397343	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397343&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174583	405267403							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794076	Fc1cnc(Nc2ccc(C=C)nc2)nc1N[C@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C19H21FN6O/c1-3-13-7-8-14(10-21-13)24-19-22-11-16(20)18(25-19)23-15-6-5-9-26(12-15)17(27)4-2/h3-4,7-8,10-11,15H,1-2,5-6,9,12H2,(H2,22,23,24,25)	ZVHVNFVWTVHTHU-UHFFFAOYSA-N	397344	US9987276, Compound I-197	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397344	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397344&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122634990	405267404							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794077	CC(C)(C)OC(=O)NCCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C27H31FN6O4/c1-5-23(35)31-19-8-6-9-20(16-19)32-24-22(28)17-30-25(34-24)33-18-10-12-21(13-11-18)37-15-7-14-29-26(36)38-27(2,3)4/h5-6,8-13,16-17H,1,7,14-15H2,2-4H3,(H,29,36)(H,31,35)(H2,30,32,33,34)	RCMAVJXUAZABPB-UHFFFAOYSA-N	397242	US9987276, Compound I-198::US10596172, Compound I-198::US10828300, Compound I-198::US11351168, Compound I-198	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397242	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397242&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174723	405267309							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794078	CC(=C)C(=O)c1cccc(Nc2nc(Nc3cccc(OC(F)(F)F)c3)ncc2F)c1	InChI=1S/C21H16F4N4O2/c1-12(2)18(30)13-5-3-6-14(9-13)27-19-17(22)11-26-20(29-19)28-15-7-4-8-16(10-15)31-21(23,24)25/h3-11H,1H2,2H3,(H2,26,27,28,29)	YQEJTFBEHMVKDF-UHFFFAOYSA-N	397243	US9987276, Compound I-199::US10596172, Compound I-199::US10828300, Compound I-199::US11351168, Compound I-199	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397243	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397243&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174306	405267310							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794079	COc1cccc(Nc2ncc(C(=O)Nc3ccccc3)c(Oc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C27H23N5O4/c1-3-24(33)29-19-11-8-14-22(16-19)36-26-23(25(34)30-18-9-5-4-6-10-18)17-28-27(32-26)31-20-12-7-13-21(15-20)35-2/h3-17H,1H2,2H3,(H,29,33)(H,30,34)(H,28,31,32)	ADLFHJTYDXPSHU-UHFFFAOYSA-N	397244	US9987276, Compound I-200::US10828300, Compound I-200::US11351168, Compound I-200	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397244	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397244&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174603	405267311							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794080	COc1cccc(Nc2ncc(F)c(NC3CCN(C3)C(=O)C=C)n2)c1	InChI=1S/C18H20FN5O2/c1-3-16(25)24-8-7-13(11-24)21-17-15(19)10-20-18(23-17)22-12-5-4-6-14(9-12)26-2/h3-6,9-10,13H,1,7-8,11H2,2H3,(H2,20,21,22,23)	RAKFXZZYPMLVRD-UHFFFAOYSA-N	397245	US9987276, Compound I-201::US10596172, Compound I-201::US10828300, Compound I-201::US11351168, Compound I-201	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397245	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397245&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174573	405267312							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794081	COc1ccc(Nc2ncc(F)c(N[C@@H]3CCCN(C3)C(=O)C=C)n2)cn1 |r|	InChI=1S/C18H21FN6O2/c1-3-16(26)25-8-4-5-13(11-25)22-17-14(19)10-21-18(24-17)23-12-6-7-15(27-2)20-9-12/h3,6-7,9-10,13H,1,4-5,8,11H2,2H3,(H2,21,22,23,24)	XQDQSYIWZYRTLU-UHFFFAOYSA-N	397246	US9987276, Compound I-202::US10596172, Compound I-202::US10828300, Compound I-202::US11351168, Compound I-202	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397246	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397246&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174367	405267313							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794082	COc1ccc(Nc2ncc(F)c(NC3CCN(C3)C(=O)C=C)n2)cn1	InChI=1S/C17H19FN6O2/c1-3-15(25)24-7-6-12(10-24)21-16-13(18)9-20-17(23-16)22-11-4-5-14(26-2)19-8-11/h3-5,8-9,12H,1,6-7,10H2,2H3,(H2,20,21,22,23)	GDOJKORDQXUFBU-UHFFFAOYSA-N	397345	US9987276, Compound I-203::US10596172, Compound I-203::US10828300, Compound I-203::US11351168, Compound I-203	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397345&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174602	405267405							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794083	Fc1cnc(Nc2cccc(OCCCn3ccnc3)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C25H24FN7O2/c1-2-23(34)29-18-6-3-7-19(14-18)30-24-22(26)16-28-25(32-24)31-20-8-4-9-21(15-20)35-13-5-11-33-12-10-27-17-33/h2-4,6-10,12,14-17H,1,5,11,13H2,(H,29,34)(H2,28,30,31,32)	NRCNNNKRVGICGY-UHFFFAOYSA-N	397247	US9987276, Compound I-204::US10596172, Compound I-204::US10828300, Compound I-204::US11351168, Compound I-204	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397247	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397247&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174666	405267314							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794084	Cc1cnc(Nc2ccccc2)nc1Nc1cccc(CNC(=O)C=C)c1	InChI=1S/C21H21N5O/c1-3-19(27)22-14-16-8-7-11-18(12-16)24-20-15(2)13-23-21(26-20)25-17-9-5-4-6-10-17/h3-13H,1,14H2,2H3,(H,22,27)(H2,23,24,25,26)	LXICWWVSTRILOW-UHFFFAOYSA-N	397346	US9987276, Compound I-205::US10596172, Compound I-205::US10828300, Compound I-205::US11351168, Compound I-205	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397346	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397346&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594260	405267406							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794085	[#6]\[#6](-[#6])=[#6]\[#6](=O)-c1ccc(-[#7]-c2nc(-[#7]-c3ccccc3)ncc2F)cc1	InChI=1S/C21H10FN4O/c1-14(2)12-19(27)15-8-10-17(11-9-15)24-20-18(22)13-23-21(26-20)25-16-6-4-3-5-7-16/h3-11,13H	RARFMJFGZNSYGW-UHFFFAOYSA-N	397347	US9987276, Compound I-206::US10596172, Compound I-206::US10828300, Compound I-206::US11351168, Compound I-206	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397347	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397347&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174492	405267407							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794086	[#6]-[#7](-[#6])-[#6]-[#6]-[#8]-c1cccc(-[#7]-c2ncc(F)c(-[#7]-c3cccc(c3)-[#6](=O)\[#6]=[#6](\[#6])-[#6])n2)c1	InChI=1S/C25H9FN5O2/c1-17(2)13-23(32)18-7-5-8-19(14-18)28-24-22(26)16-27-25(30-24)29-20-9-6-10-21(15-20)33-12-11-31(3)4/h5-10,14-16H	OGHIUDKYGROMIY-UHFFFAOYSA-N	397248	US9987276, Compound I-207::US10596172, Compound I-207::US10828300, Compound I-207::US11351168, Compound I-207	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397248	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397248&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174332	405267315							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794087	Fc1cnc(Nc2cccc(OCCCN3CCOCC3)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C26H29FN6O3/c1-2-24(34)29-19-6-3-7-20(16-19)30-25-23(27)18-28-26(32-25)31-21-8-4-9-22(17-21)36-13-5-10-33-11-14-35-15-12-33/h2-4,6-9,16-18H,1,5,10-15H2,(H,29,34)(H2,28,30,31,32)	VDUDICQYCWGKOX-UHFFFAOYSA-N	397249	US9987276, Compound I-208::US10596172, Compound I-208::US10828300, Compound I-208::US11351168, Compound I-208	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397249	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397249&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174527	405267316							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794088	COc1ccc(Nc2ncc(C(N)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C20H19N7O3/c1-3-16(28)24-12-5-4-6-13(9-12)25-19-15(18(21)29)11-23-20(27-19)26-14-7-8-17(30-2)22-10-14/h3-11H,1H2,2H3,(H2,21,29)(H,24,28)(H2,23,25,26,27)	SYYNDLKMSVUFCY-UHFFFAOYSA-N	397250	US9987276, Compound I-209::US10596172, Compound I-209::US10828300, Compound I-209::US11351168, Compound I-209	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397250	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397250&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174516	405267317							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794089	COc1cccc(Nc2ncc(C(N)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C21H20N6O3/c1-3-18(28)24-13-6-4-7-14(10-13)25-20-17(19(22)29)12-23-21(27-20)26-15-8-5-9-16(11-15)30-2/h3-12H,1H2,2H3,(H2,22,29)(H,24,28)(H2,23,25,26,27)	YQGWYHRINGUJLC-UHFFFAOYSA-N	397230	US9987276, Compound I-178::US9987276, Compound I-210::US10596172, Compound I-210::US10828300, Compound I-210::US11351168, Compound I-210	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397230	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397230&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174418	405267298							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794090	[#6]\[#6](-[#6])=[#6]\[#6](=O)-c1cccc(-[#7]-c2nc(-[#7]-c3cccc(-[#8]-[#6]C#C)c3)ncc2F)c1	InChI=1S/C24H10FN4O2/c1-4-11-31-20-10-6-9-19(14-20)28-24-26-15-21(25)23(29-24)27-18-8-5-7-17(13-18)22(30)12-16(2)3/h1,5-10,13-15H	KBHAGYBSAHQUSE-UHFFFAOYSA-N	397348	US9987276, Compound I-211::US10596172, Compound I-211::US10828300, Compound I-211::US11351168, Compound I-211	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397348	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397348&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174684	405267408							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794091	Fc1cnc(Nc2cccc(NC(=O)C=C)c2)nc1Oc1ccc(Oc2ccccc2)cc1	InChI=1S/C25H19FN4O3/c1-2-23(31)28-17-7-6-8-18(15-17)29-25-27-16-22(26)24(30-25)33-21-13-11-20(12-14-21)32-19-9-4-3-5-10-19/h2-16H,1H2,(H,28,31)(H,27,29,30)	GCUYAORKXCVHIX-UHFFFAOYSA-N	397349	US9987276, Compound I-212::US10596172, Compound I-212::US10828300, Compound I-212::US11351168, Compound I-212	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397349	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397349&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174511	405267409							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794092	[#6]-[#8]-c1cccc(-[#7]-c2ncc(c(-[#7]-[#6@@H]-3-[#6]-[#6]-[#6]-[#6@@H](-[#6]-3)-[#6](=O)\[#6]=[#6](\[#6])-[#6])n2)C(F)(F)F)c1 |r|	InChI=1S/C23H7F3N4O2/c1-14(2)10-20(31)15-6-4-7-16(11-15)28-21-19(23(24,25)26)13-27-22(30-21)29-17-8-5-9-18(12-17)32-3/h5,8-9,12-13,15-16H	ZFERBEBDTCHAHC-UHFFFAOYSA-N	397350	US9987276, Compound I-213::US10596172, Compound I-213::US10828300, Compound I-213::US11351168, Compound I-213	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397350	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397350&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174535	405267410							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794093	COc1cncc(Nc2ncc(c(Nc3ccc(NC(=O)C=C)cc3)n2)C(F)(F)F)c1	InChI=1S/C20H17F3N6O2/c1-3-17(30)26-12-4-6-13(7-5-12)27-18-16(20(21,22)23)11-25-19(29-18)28-14-8-15(31-2)10-24-9-14/h3-11H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	MHIWASIZKKCXCN-UHFFFAOYSA-N	397351	US9987276, Compound I-214::US10596172, Compound I-214::US10828300, Compound I-214::US11351168, Compound I-214	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397351	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397351&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174680	405267411							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794094	Cc1cnc(Nc2cccc(OCCCNC(=O)CCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)c2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C48H68N10O9S/c1-3-41(59)53-35-12-6-13-36(30-35)54-46-34(2)32-52-47(58-46)55-37-14-7-15-38(31-37)67-25-11-22-51-44(62)19-8-18-43(61)50-21-10-24-65-27-29-66-28-26-64-23-9-20-49-42(60)17-5-4-16-40-45-39(33-68-40)56-48(63)57-45/h3,6-7,12-15,30-32,39-40,45H,1,4-5,8-11,16-29,33H2,2H3,(H,49,60)(H,50,61)(H,51,62)(H,53,59)(H2,56,57,63)(H2,52,54,55,58)	SBOPEFHTOFMNSD-UHFFFAOYSA-N	397252	US9987276, Compound I-215::US10596172, Compound I-215::US10828300, Compound I-215::US11351168, Compound I-215	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397252	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397252&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174509	405267318							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794095	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(C)(C)C)cn1	InChI=1S/C23H26N6O2/c1-6-19(30)26-15-8-7-9-16(12-15)27-21-18(23(2,3)4)14-25-22(29-21)28-17-10-11-20(31-5)24-13-17/h6-14H,1H2,2-5H3,(H,26,30)(H2,25,27,28,29)	VGNREORVOUDCRV-UHFFFAOYSA-N	397352	US9987276, Compound I-216	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397352	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397352&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			122634991	405267412							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794096	COc1ccc(Nc2ncc(F)c(Oc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C19H16FN5O3/c1-3-16(26)23-12-5-4-6-14(9-12)28-18-15(20)11-22-19(25-18)24-13-7-8-17(27-2)21-10-13/h3-11H,1H2,2H3,(H,23,26)(H,22,24,25)	AZFYXBXDTZLJGD-UHFFFAOYSA-N	397253	US9987276, Compound I-217::US10596172, Compound I-217::US10828300, Compound I-217::US11351168, Compound I-217	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397253	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397253&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174479	405267319							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794097	COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)cn1	InChI=1S/C20H17F3N6O2/c1-3-16(30)26-12-5-4-6-13(9-12)27-18-15(20(21,22)23)11-25-19(29-18)28-14-7-8-17(31-2)24-10-14/h3-11H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	JGDXUIGGWKJQED-UHFFFAOYSA-N	397254	US9987276, Compound I-218::US10596172, Compound I-218::US10828300, Compound I-218::US11351168, Compound I-218	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397254	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397254&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174641	405267320							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794098	CN(Cc1ccc(Nc2nc(Nc3ccccc3)ncc2C)cc1)C(=O)C=C	InChI=1S/C22H23N5O/c1-4-20(28)27(3)15-17-10-12-19(13-11-17)24-21-16(2)14-23-22(26-21)25-18-8-6-5-7-9-18/h4-14H,1,15H2,2-3H3,(H2,23,24,25,26)	YBESIBQNBNKGKU-UHFFFAOYSA-N	397255	US9987276, Compound I-219::US10596172, Compound I-219::US10828300, Compound I-219::US11351168, Compound I-219	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397255	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397255&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174546	405267321							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794099	CN(Cc1cccc(Nc2nc(Nc3ccccc3)ncc2C)c1)C(=O)C=C	InChI=1S/C22H23N5O/c1-4-20(28)27(3)15-17-9-8-12-19(13-17)24-21-16(2)14-23-22(26-21)25-18-10-6-5-7-11-18/h4-14H,1,15H2,2-3H3,(H2,23,24,25,26)	HBKAUVDNJUGBBG-UHFFFAOYSA-N	397256	US9987276, Compound I-220::US10596172, Compound I-220::US10828300, Compound I-220::US11351168, Compound I-220	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397256	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397256&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174473	405267322							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794100	C=CC(=O)Nc1cccc(Nc2nc(Nc3ccccc3)ncc2C(=O)NC2CC2)c1	InChI=1S/C23H22N6O2/c1-2-20(30)25-17-9-6-10-18(13-17)26-21-19(22(31)27-16-11-12-16)14-24-23(29-21)28-15-7-4-3-5-8-15/h2-10,13-14,16H,1,11-12H2,(H,25,30)(H,27,31)(H2,24,26,28,29)	FKLZHEFUQKMNLE-UHFFFAOYSA-N	397353	US9987276, Compound I-221::US10596172, Compound I-221::US10828300, Compound I-221::US11351168, Compound I-221	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397353&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174312	405267413							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794101	C=CC(=O)Nc1cccc(Nc2nc(Nc3ccccc3)ncc2C(=O)Nc2ccccc2)c1	InChI=1S/C26H22N6O2/c1-2-23(33)28-20-14-9-15-21(16-20)29-24-22(25(34)30-18-10-5-3-6-11-18)17-27-26(32-24)31-19-12-7-4-8-13-19/h2-17H,1H2,(H,28,33)(H,30,34)(H2,27,29,31,32)	DRQBACKFLKRFJX-UHFFFAOYSA-N	397354	US9987276, Compound I-222::US10596172, Compound I-222::US10828300, Compound I-222::US11351168, Compound I-222	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397354&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174577	405267414							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794102	[#6]\[#6](-[#6])=[#6]\[#6](=O)-c1cccc(-[#7]-c2nc(-[#7]-c3cccc(-[#8]C(F)(F)F)c3)ncc2F)c1	InChI=1S/C22H9F4N4O2/c1-13(2)9-19(31)14-5-3-6-15(10-14)28-20-18(23)12-27-21(30-20)29-16-7-4-8-17(11-16)32-22(24,25)26/h3-8,10-12H	BNWBVACYAHVKIX-UHFFFAOYSA-N	397355	BDBM437889::US9987276, Compound I-223::US10828300, Compound I-223::US11351168, Compound I-223	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397355&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174660	405267415							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794103	[#6]\[#6](-[#6])=[#6]\[#6](=O)-c1cccc(-[#7]-c2nc(-[#7]-c3cccc(c3)S([#7])(=O)=O)ncc2-[#6])c1	InChI=1S/C22H9N5O3S/c1-14(2)10-20(28)16-6-4-7-17(11-16)25-21-15(3)13-24-22(27-21)26-18-8-5-9-19(12-18)31(23,29)30/h4-9,11-13H	NDFFACDFSKBVFR-UHFFFAOYSA-N	397356	US9987276, Compound I-224::BDBM437890::US10828300, Compound I-224::US11351168, Compound I-224	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397356&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594693	405267416							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794104	[#6]-[#8]-c1cccc(-[#7]-c2ncc(c(-[#7]-c3cccc(c3)-[#6](=O)\[#6]=[#6](\[#6])-[#6])n2)C(F)(F)F)c1	InChI=1S/C23H9F3N4O2/c1-14(2)10-20(31)15-6-4-7-16(11-15)28-21-19(23(24,25)26)13-27-22(30-21)29-17-8-5-9-18(12-17)32-3/h4-9,11-13H	QCDWQUMXVVNHGG-UHFFFAOYSA-N	397357	US9987276, Compound I-225::US10596172, Compound I-225::US10828300, Compound I-225::US11351168, Compound I-225	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397357	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397357&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174581	405267417							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794105	COc1cccc(Nc2ncc(c(Nc3cccc(CNC(=O)C=C)c3)n2)C(F)(F)F)c1	InChI=1S/C22H20F3N5O2/c1-3-19(31)26-12-14-6-4-7-15(10-14)28-20-18(22(23,24)25)13-27-21(30-20)29-16-8-5-9-17(11-16)32-2/h3-11,13H,1,12H2,2H3,(H,26,31)(H2,27,28,29,30)	WYCSNQIXUMKZPH-UHFFFAOYSA-N	397358	US9987276, Compound I-226::US10596172, Compound I-226::US10828300, Compound I-226::US11351168, Compound I-226	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397358&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174449	405267418							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794106	COc1cccc(Nc2ncc(c(Nc3ccc(Cl)c(NC(=O)C=C)c3)n2)C(F)(F)F)c1	InChI=1S/C21H17ClF3N5O2/c1-3-18(31)29-17-10-13(7-8-16(17)22)27-19-15(21(23,24)25)11-26-20(30-19)28-12-5-4-6-14(9-12)32-2/h3-11H,1H2,2H3,(H,29,31)(H2,26,27,28,30)	YLUIPOSHQRPNFC-UHFFFAOYSA-N	397257	US9987276, Compound I-227::US10596172, Compound I-227::US10828300, Compound I-227::US11351168, Compound I-227	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397257	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397257&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174617	405267323							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794107	Fc1cnc(Nc2ccccc2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C19H15FN4O2/c1-2-17(25)22-14-9-6-10-15(11-14)26-18-16(20)12-21-19(24-18)23-13-7-4-3-5-8-13/h2-12H,1H2,(H,22,25)(H,21,23,24)	TXORKGYZMUSRKS-UHFFFAOYSA-N	397258	US9987276, Compound I-228::US10596172, Compound I-228::US10828300, Compound I-228::US11351168, Compound I-228	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397258	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397258&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174544	405267324							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794108	Fc1cnc(Nc2ccccc2)nc1NC1CCN(CC1)C(=O)C=C	InChI=1S/C18H20FN5O/c1-2-16(25)24-10-8-14(9-11-24)21-17-15(19)12-20-18(23-17)22-13-6-4-3-5-7-13/h2-7,12,14H,1,8-11H2,(H2,20,21,22,23)	FPSJXFSHFMEJMT-UHFFFAOYSA-N	397359	US9987276, Compound I-229::US10596172, Compound I-229::US10828300, Compound I-229::US11351168, Compound I-229	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397359	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397359&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174283	405267419							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794109	NC(=O)c1cnc(Nc2ccccc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C20H18N6O2/c1-2-17(27)23-14-9-6-10-15(11-14)24-19-16(18(21)28)12-22-20(26-19)25-13-7-4-3-5-8-13/h2-12H,1H2,(H2,21,28)(H,23,27)(H2,22,24,25,26)	WZGZMOKAYDSSEC-UHFFFAOYSA-N	397259	US9987276, Compound I-230::US10596172, Compound I-230::US10828300, Compound I-230::US11351168, Compound I-230	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397259	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397259&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174485	405267325							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794110	COc1ccc(CNC(=O)c2cnc(Nc3ccccc3)nc2Nc2cccc(NC(=O)C=C)c2)cc1	InChI=1S/C28H26N6O3/c1-3-25(35)31-21-10-7-11-22(16-21)32-26-24(18-30-28(34-26)33-20-8-5-4-6-9-20)27(36)29-17-19-12-14-23(37-2)15-13-19/h3-16,18H,1,17H2,2H3,(H,29,36)(H,31,35)(H2,30,32,33,34)	VZEQZRBNNXFIRE-UHFFFAOYSA-N	397360	US9987276, Compound I-231::US10596172, Compound I-231::US10828300, Compound I-231::US11351168, Compound I-231	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397360	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397360&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174388	405267420							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794111	[#6]\[#6](-[#6])=[#6]\[#6](=O)-c1cccc(-[#7]-c2nc(-[#7]-c3ccccc3)ncc2-[#6])c1	InChI=1S/C22H10N4O/c1-15(2)12-20(27)17-8-7-11-19(13-17)24-21-16(3)14-23-22(26-21)25-18-9-5-4-6-10-18/h4-11,13-14H	JEOWVCHDSYKKDD-UHFFFAOYSA-N	397361	US9987276, Compound I-232::US10596172, Compound I-232::US10828300, Compound I-232::US11351168, Compound I-232	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397361	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397361&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594831	405267421							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794112	CN(C)CCOc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C23H25FN6O2/c1-4-21(31)26-16-7-5-8-17(13-16)27-22-20(24)15-25-23(29-22)28-18-9-6-10-19(14-18)32-12-11-30(2)3/h4-10,13-15H,1,11-12H2,2-3H3,(H,26,31)(H2,25,27,28,29)	QXTSOWYCAPKWJX-UHFFFAOYSA-N	397260	US9987276, Compound I-233::US10596172, Compound I-233::US10828300, Compound I-233::US11351168, Compound I-233	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397260	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397260&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174662	405267326							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794113	Fc1cnc(Nc2cccnc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C18H15FN6O/c1-2-16(26)22-12-5-3-6-13(9-12)23-17-15(19)11-21-18(25-17)24-14-7-4-8-20-10-14/h2-11H,1H2,(H,22,26)(H2,21,23,24,25)	XCCGVXVYNJGEHR-UHFFFAOYSA-N	397362	US9987276, Compound I-234::US10596172, Compound I-234::US10828300, Compound I-234::US11351168, Compound I-234	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397362	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397362&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174555	405267422							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794114	COc1cccc(Nc2ncc(c(Nc3ccc(CNC(=O)C=C)cc3)n2)C(F)(F)F)c1	InChI=1S/C22H20F3N5O2/c1-3-19(31)26-12-14-7-9-15(10-8-14)28-20-18(22(23,24)25)13-27-21(30-20)29-16-5-4-6-17(11-16)32-2/h3-11,13H,1,12H2,2H3,(H,26,31)(H2,27,28,29,30)	YDOCWOOVIQMFLD-UHFFFAOYSA-N	397363	US9987276, Compound I-235::US10596172, Compound I-235::US10828300, Compound I-235::US11351168, Compound I-235	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397363	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397363&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174381	405267423							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794115	COc1cccc(Nc2ncc(c(Nc3ccc(NC(=O)C=C)cc3)n2)C(F)(F)F)c1	InChI=1S/C21H18F3N5O2/c1-3-18(30)26-13-7-9-14(10-8-13)27-19-17(21(22,23)24)12-25-20(29-19)28-15-5-4-6-16(11-15)31-2/h3-12H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	WKLNENAGIRMOOF-UHFFFAOYSA-N	397364	US9987276, Compound I-236::US10596172, Compound I-236::US10828300, Compound I-236::US11351168, Compound I-236	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397364	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397364&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174504	405267424							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794116	Cc1cnc(Nc2cccc(OCCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)c2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C33H40N8O4S/c1-3-28(42)36-22-9-6-10-23(17-22)37-31-21(2)19-35-32(41-31)38-24-11-7-12-25(18-24)45-16-8-15-34-29(43)14-5-4-13-27-30-26(20-46-27)39-33(44)40-30/h3,6-7,9-12,17-19,26-27,30H,1,4-5,8,13-16,20H2,2H3,(H,34,43)(H,36,42)(H2,39,40,44)(H2,35,37,38,41)	DTSZIQFFZCDXNB-UHFFFAOYSA-N	397261	US9987276, Compound I-237::US10596172, Compound I-237::US10828300, Compound I-237::US11351168, Compound I-237	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397261	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397261&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174787	405267327							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794117	CC(=O)N1CCCC(C1)Nc1ncc(F)c(Nc2cccc(NC(=O)C=C)c2)n1	InChI=1S/C20H23FN6O2/c1-3-18(29)23-14-6-4-7-15(10-14)24-19-17(21)11-22-20(26-19)25-16-8-5-9-27(12-16)13(2)28/h3-4,6-7,10-11,16H,1,5,8-9,12H2,2H3,(H,23,29)(H2,22,24,25,26)	SFOZLSQRYWURRO-UHFFFAOYSA-N	397365	US9987276, Compound I-238::US10596172, Compound I-238::US10828300, Compound I-238::US11351168, Compound I-238	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397365	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397365&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174636	405267425							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794118	COc1ccc(CNc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C21H20FN5O2/c1-3-19(28)25-15-5-4-6-16(11-15)26-20-18(22)13-24-21(27-20)23-12-14-7-9-17(29-2)10-8-14/h3-11,13H,1,12H2,2H3,(H,25,28)(H2,23,24,26,27)	OJFPPWSHCNEZAG-UHFFFAOYSA-N	397366	US9987276, Compound I-241::US10596172, Compound I-241::US10828300, Compound I-241::US11351168, Compound I-241	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397366	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397366&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174383	405267426							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794119	COc1cccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1	InChI=1S/C21H18F3N5O2/c1-3-18(30)26-13-6-4-7-14(10-13)27-19-17(21(22,23)24)12-25-20(29-19)28-15-8-5-9-16(11-15)31-2/h3-12H,1H2,2H3,(H,26,30)(H2,25,27,28,29)	HHTIMWWVFHMEGZ-UHFFFAOYSA-N	397262	US9987276, Compound I-242::US10596172, Compound I-242::US10828300, Compound I-242::US11351168, Compound I-242	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397262	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397262&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174638	405267328							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794120	COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C19H17FN6O2/c1-3-16(27)23-12-5-4-6-13(9-12)24-18-15(20)11-22-19(26-18)25-14-7-8-17(28-2)21-10-14/h3-11H,1H2,2H3,(H,23,27)(H2,22,24,25,26)	LVQDMCXIIKGTTL-UHFFFAOYSA-N	397172	US9987276, Compound I-95::US9987276, Compound I-243::US10596172, Compound I-243::US10828300, Compound I-243::US11351168, Compound I-243	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397172	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397172&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174476	405267240							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794121	Fc1cnc(Nc2cccc(OC(F)(F)F)c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C20H15F4N5O2/c1-2-17(30)26-12-5-3-6-13(9-12)27-18-16(21)11-25-19(29-18)28-14-7-4-8-15(10-14)31-20(22,23)24/h2-11H,1H2,(H,26,30)(H2,25,27,28,29)	WBSUDFJWEDXFTH-UHFFFAOYSA-N	397264	US9987276, Compound I-244::US10596172, Compound I-244::US10828300, Compound I-244::US11351168, Compound I-244	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397264	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397264&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174451	405267329							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794122	FC(F)(F)c1cnc(Nc2ccccc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C20H16F3N5O/c1-2-17(29)25-14-9-6-10-15(11-14)26-18-16(20(21,22)23)12-24-19(28-18)27-13-7-4-3-5-8-13/h2-12H,1H2,(H,25,29)(H2,24,26,27,28)	PPDBSPSBLFWMDS-UHFFFAOYSA-N	397265	US9987276, Compound I-245::US10596172, Compound I-245::US10828300, Compound I-245::US11351168, Compound I-245	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397265	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397265&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174343	405267330							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794123	C\C=C\C(=O)OCc1cccc(Nc2nc(Nc3ccccc3)ncc2C)c1	InChI=1S/C22H22N4O2/c1-3-8-20(27)28-15-17-9-7-12-19(13-17)24-21-16(2)14-23-22(26-21)25-18-10-5-4-6-11-18/h3-14H,15H2,1-2H3,(H2,23,24,25,26)	QKZGEULCBCCZIK-UHFFFAOYSA-N	397367	US9987276, Compound I-246::US10596172, Compound I-246::US10828300, Compound I-246::US11351168, Compound I-246	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397367&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594261	405267427							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794124	Fc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C19H15F2N5O/c1-2-17(27)23-14-4-3-5-15(10-14)24-18-16(21)11-22-19(26-18)25-13-8-6-12(20)7-9-13/h2-11H,1H2,(H,23,27)(H2,22,24,25,26)	VPIIYIKGMZOSMS-UHFFFAOYSA-N	397266	US9987276, Compound I-247::US10596172, Compound I-247::US10828300, Compound I-247::US11351168, Compound I-247	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397266	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397266&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174563	405267331							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794125	Cc1cnc(Nc2ccccc2)nc1Oc1cccc(NC(=O)C=C)c1	InChI=1S/C20H18N4O2/c1-3-18(25)22-16-10-7-11-17(12-16)26-19-14(2)13-21-20(24-19)23-15-8-5-4-6-9-15/h3-13H,1H2,2H3,(H,22,25)(H,21,23,24)	YJEIATTXCFELRT-UHFFFAOYSA-N	397267	US9987276, Compound I-248::US10596172, Compound I-248::US10828300, Compound I-248::US11351168, Compound I-248	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397267	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397267&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44594836	405267332							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794126	CC(C)(O)COc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl	InChI=1S/C23H23ClFN5O3/c1-4-20(31)27-14-6-5-7-15(10-14)28-21-18(25)12-26-22(30-21)29-16-8-9-17(24)19(11-16)33-13-23(2,3)32/h4-12,32H,1,13H2,2-3H3,(H,27,31)(H2,26,28,29,30)	IRTRSPMVHUQQPX-UHFFFAOYSA-N	397268	US9987276, Compound I-249::US10596172, Compound I-249::US10828300, Compound I-249::US11351168, Compound I-249	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397268	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397268&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174789	405267333							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794127	CC(C)(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(c3)C(O)C(=C)C#N)n2)cn1	InChI=1S/C23H23FN6O3/c1-14(10-25)20(31)15-5-4-6-16(9-15)28-21-18(24)12-27-22(30-21)29-17-7-8-19(26-11-17)33-13-23(2,3)32/h4-9,11-12,20,31-32H,1,13H2,2-3H3,(H2,27,28,29,30)	UWZJEIMGNQTGCQ-UHFFFAOYSA-N	397368	US9987276, Compound I-312::US10596172, Compound I-312::US10828300, Compound I-312::US11351168, Compound I-312	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397368&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174520	405267428							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794128	CC(C)(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1	InChI=1S/C22H23FN6O3/c1-4-18(30)26-14-6-5-7-15(10-14)27-20-17(23)12-25-21(29-20)28-16-8-9-19(24-11-16)32-13-22(2,3)31/h4-12,31H,1,13H2,2-3H3,(H,26,30)(H2,25,27,28,29)	YYBUJDSEMIDJKA-UHFFFAOYSA-N	397269	US9987276, Compound I-313::US10596172, Compound I-313::US10828300, Compound I-313::US11351168, Compound I-313	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397269	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397269&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174311	405267334							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794129	CC(C)(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C23H23F2N5O3/c1-4-20(31)27-14-6-5-7-15(10-14)28-21-18(25)12-26-22(30-21)29-16-8-9-19(17(24)11-16)33-13-23(2,3)32/h4-12,32H,1,13H2,2-3H3,(H,27,31)(H2,26,28,29,30)	XMTMZIVGULRXHT-UHFFFAOYSA-N	397270	US9987276, Compound I-315::US10596172, Compound I-315::US10828300, Compound I-315::US11351168, Compound I-315	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397270	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397270&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174610	405267335							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794130	Fc1cnc(Nc2ccc(O[C@@H]3CCOC3)c(F)c2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C23H21F2N5O3/c1-2-21(31)27-14-4-3-5-15(10-14)28-22-19(25)12-26-23(30-22)29-16-6-7-20(18(24)11-16)33-17-8-9-32-13-17/h2-7,10-12,17H,1,8-9,13H2,(H,27,31)(H2,26,28,29,30)	JLGAHHJQXBLBSK-UHFFFAOYSA-N	397271	US9987276, Compound I-316::US10596172, Compound I-316::US10828300, Compound I-316::US11351168, Compound I-316	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397271	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397271&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174596	405267336							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794131	CS(=O)(=O)CCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C23H23F2N5O4S/c1-3-21(31)27-15-6-4-7-16(12-15)28-22-19(25)14-26-23(30-22)29-17-8-9-20(18(24)13-17)34-10-5-11-35(2,32)33/h3-4,6-9,12-14H,1,5,10-11H2,2H3,(H,27,31)(H2,26,28,29,30)	XMXULPDQKZIBID-UHFFFAOYSA-N	397272	US9987276, Compound I-318::US10596172, Compound I-318::US10828300, Compound I-318::US11351168, Compound I-318	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397272	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397272&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174575	405267337							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794132	COCCOc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl	InChI=1S/C22H21ClFN5O3/c1-3-20(30)26-14-5-4-6-15(11-14)27-21-18(24)13-25-22(29-21)28-16-7-8-17(23)19(12-16)32-10-9-31-2/h3-8,11-13H,1,9-10H2,2H3,(H,26,30)(H2,25,27,28,29)	WHFJYOFTDFOGST-UHFFFAOYSA-N	397273	US9987276, Compound I-321::US10596172, Compound I-321::US10828300, Compound I-321::US11351168, Compound I-321	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397273	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397273&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174375	405267338							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794133	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(c3)C(=O)C(C)=C)n2)cc1F	InChI=1S/C23H22F2N4O3/c1-14(2)21(30)15-5-4-6-16(11-15)27-22-19(25)13-26-23(29-22)28-17-7-8-20(18(24)12-17)32-10-9-31-3/h4-8,11-13H,1,9-10H2,2-3H3,(H2,26,27,28,29)	VXHVKNHBTCMKOB-UHFFFAOYSA-N	397274	US9987276, Compound I-322::US10596172, Compound I-322::US10828300, Compound I-322::US11351168, Compound I-322	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397274	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397274&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174350	405267339							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794134	[#6]-[#8]-[#6]-[#6]-[#8]-c1ccc(-[#7]-c2ncc(F)c(-[#7]-c3cccc(c3)-[#6](=O)\[#6]=[#6](\[#6])-[#6])n2)cc1F	InChI=1S/C24H8F2N4O3/c1-15(2)11-21(31)16-5-4-6-17(12-16)28-23-20(26)14-27-24(30-23)29-18-7-8-22(19(25)13-18)33-10-9-32-3/h4-8,12-14H	OGILCJIQHVHVMA-UHFFFAOYSA-N	397369	US9987276, Compound I-323::US10596172, Compound I-323::US10828300, Compound I-323::US11351168, Compound I-323	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397369	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397369&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174420	405267429							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794135	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc(cc3)C(=O)C(C)=C)n2)cc1F	InChI=1S/C23H22F2N4O3/c1-14(2)21(30)15-4-6-16(7-5-15)27-22-19(25)13-26-23(29-22)28-17-8-9-20(18(24)12-17)32-11-10-31-3/h4-9,12-13H,1,10-11H2,2-3H3,(H2,26,27,28,29)	IMVXXEOXDBRIHH-UHFFFAOYSA-N	397275	US9987276, Compound I-324::US10596172, Compound I-324::US10828300, Compound I-324::US11351168, Compound I-324	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397275	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397275&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174417	405267340							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794136	[#6]-[#8]-[#6]-[#6]-[#8]-c1ccc(-[#7]-c2ncc(F)c(-[#7]-c3ccc(cc3)-[#6](=O)\[#6]=[#6](\[#6])-[#6])n2)cc1F	InChI=1S/C24H8F2N4O3/c1-15(2)12-21(31)16-4-6-17(7-5-16)28-23-20(26)14-27-24(30-23)29-18-8-9-22(19(25)13-18)33-11-10-32-3/h4-9,13-14H	CVTWHBBJRAIPHC-UHFFFAOYSA-N	397370	US9987276, Compound I-325::US10596172, Compound I-325::US10828300, Compound I-325::US11351168, Compound I-325	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397370&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174667	405267430							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794137	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(c3)C(O)C(=C)C#N)n2)cc1F	InChI=1S/C23H21F2N5O3/c1-14(12-26)21(31)15-4-3-5-16(10-15)28-22-19(25)13-27-23(30-22)29-17-6-7-20(18(24)11-17)33-9-8-32-2/h3-7,10-11,13,21,31H,1,8-9H2,2H3,(H2,27,28,29,30)	TUGDIGMTHDVOSV-UHFFFAOYSA-N	397371	US9987276, Compound I-326::US10596172, Compound I-326::US10828300, Compound I-326::US11351168, Compound I-326	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397371	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397371&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174442	405267431							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794138	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc(cc3)C(O)C(=C)C#N)n2)cc1F	InChI=1S/C23H21F2N5O3/c1-14(12-26)21(31)15-3-5-16(6-4-15)28-22-19(25)13-27-23(30-22)29-17-7-8-20(18(24)11-17)33-10-9-32-2/h3-8,11,13,21,31H,1,9-10H2,2H3,(H2,27,28,29,30)	MEWVTYJXQFFSRY-UHFFFAOYSA-N	397372	US9987276, Compound I-327::US10596172, Compound I-327::US10828300, Compound I-327::US11351168, Compound I-327	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397372&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174748	405267432							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794139	COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(CC(=O)C(C)=C)c3)n2)cc1F	InChI=1S/C24H24F2N4O3/c1-15(2)21(31)12-16-5-4-6-17(11-16)28-23-20(26)14-27-24(30-23)29-18-7-8-22(19(25)13-18)33-10-9-32-3/h4-8,11,13-14H,1,9-10,12H2,2-3H3,(H2,27,28,29,30)	UZPGPNPHWOOVAT-UHFFFAOYSA-N	397373	US9987276, Compound I-328::US10596172, Compound I-328::US10828300, Compound I-328::US11351168, Compound I-328	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397373&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174482	405267433							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794140	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc(CC(=O)C(C)=C)cc3)n2)cc1F	InChI=1S/C24H24F2N4O3/c1-15(2)21(31)12-16-4-6-17(7-5-16)28-23-20(26)14-27-24(30-23)29-18-8-9-22(19(25)13-18)33-11-10-32-3/h4-9,13-14H,1,10-12H2,2-3H3,(H2,27,28,29,30)	DMUMOEPIMFZZHB-UHFFFAOYSA-N	397276	US9987276, Compound I-329::US10596172, Compound I-329::US10828300, Compound I-329::US11351168, Compound I-329	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397276	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397276&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174293	405267341							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794141	[#6]-[#8]-[#6]-[#6]-[#8]-c1ccc(-[#7]-c2ncc(F)c(-[#7]-c3cccc(-[#6]-[#6](=O)\[#6]=[#6](\[#6])-[#6])c3)n2)cc1F	InChI=1S/C25H8F2N4O3/c1-16(2)11-20(32)13-17-5-4-6-18(12-17)29-24-22(27)15-28-25(31-24)30-19-7-8-23(21(26)14-19)34-10-9-33-3/h4-8,12,14-15H	DZFPIKWKNCOIMQ-UHFFFAOYSA-N	397374	US9987276, Compound I-330::US10596172, Compound I-330::US10828300, Compound I-330::US11351168, Compound I-330	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397374&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174338	405267434							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794142	[#6]-[#8]-[#6]-[#6]-[#8]-c1ccc(-[#7]-c2ncc(F)c(-[#7]-c3ccc(-[#6]-[#6](=O)\[#6]=[#6](\[#6])-[#6])cc3)n2)cc1F	InChI=1S/C25H8F2N4O3/c1-16(2)12-20(32)13-17-4-6-18(7-5-17)29-24-22(27)15-28-25(31-24)30-19-8-9-23(21(26)14-19)34-11-10-33-3/h4-9,14-15H	JZZWKNMDWFWZBN-UHFFFAOYSA-N	397375	US9987276, Compound I-331::US10596172, Compound I-331::US10828300, Compound I-331::US11351168, Compound I-331	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397375&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174640	405267435							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794143	CC(C)(CO)Oc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C23H23F2N5O3/c1-4-20(32)27-14-6-5-7-15(10-14)28-21-18(25)12-26-22(30-21)29-16-8-9-19(17(24)11-16)33-23(2,3)13-31/h4-12,31H,1,13H2,2-3H3,(H,27,32)(H2,26,28,29,30)	KRTUPMZAPFHCFL-UHFFFAOYSA-N	397376	US9987276, Compound I-332::US10596172, Compound I-332::US10828300, Compound I-332::US11351168, Compound I-332	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397376	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397376&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174368	405267436							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794144	CC(CO)Oc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C22H21F2N5O3/c1-3-20(31)26-14-5-4-6-15(9-14)27-21-18(24)11-25-22(29-21)28-16-7-8-19(17(23)10-16)32-13(2)12-30/h3-11,13,30H,1,12H2,2H3,(H,26,31)(H2,25,27,28,29)	MBQOLZKCWIMGNL-UHFFFAOYSA-N	397277	US9987276, Compound I-333::US10596172, Compound I-333::US10828300, Compound I-333::US11351168, Compound I-333	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397277	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397277&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174394	405267342							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794145	OCC(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C22H21F2N5O4/c1-2-20(32)26-13-4-3-5-14(8-13)27-21-18(24)10-25-22(29-21)28-15-6-7-19(17(23)9-15)33-12-16(31)11-30/h2-10,16,30-31H,1,11-12H2,(H,26,32)(H2,25,27,28,29)	QGCMEBBNCYWNOQ-UHFFFAOYSA-N	397377	US9987276, Compound I-334::US10596172, Compound I-334::US10828300, Compound I-334::US11351168, Compound I-334	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397377&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174431	405267437							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794146	OCC(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1	InChI=1S/C22H22FN5O4/c1-2-20(31)25-15-4-3-5-16(10-15)26-21-19(23)11-24-22(28-21)27-14-6-8-18(9-7-14)32-13-17(30)12-29/h2-11,17,29-30H,1,12-13H2,(H,25,31)(H2,24,26,27,28)	ISMIFGDOPCFKSE-UHFFFAOYSA-N	397378	US9987276, Compound I-335::US10596172, Compound I-335::US10828300, Compound I-335::US11351168, Compound I-335	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397378&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174664	405267438							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794147	CC(C)(CO)Oc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl	InChI=1S/C23H23ClFN5O3/c1-4-20(32)27-14-6-5-7-15(10-14)28-21-18(25)12-26-22(30-21)29-16-8-9-17(24)19(11-16)33-23(2,3)13-31/h4-12,31H,1,13H2,2-3H3,(H,27,32)(H2,26,28,29,30)	BIIHMOIGGYMJEQ-UHFFFAOYSA-N	397278	US9987276, Compound I-336::US10596172, Compound I-336::US10828300, Compound I-336::US11351168, Compound I-336	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397278	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397278&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174710	405267343							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794148	CC(CO)Oc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl	InChI=1S/C22H21ClFN5O3/c1-3-20(31)26-14-5-4-6-15(9-14)27-21-18(24)11-25-22(29-21)28-16-7-8-17(23)19(10-16)32-13(2)12-30/h3-11,13,30H,1,12H2,2H3,(H,26,31)(H2,25,27,28,29)	VZXXRAOOPZBUJW-UHFFFAOYSA-N	397279	US9987276, Compound I-337::US10596172, Compound I-337::US10828300, Compound I-337::US11351168, Compound I-337	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397279	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397279&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174629	405267344							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794149	OCC(O)COc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1	InChI=1S/C22H22FN5O4/c1-2-20(31)25-14-5-3-6-15(9-14)26-21-19(23)11-24-22(28-21)27-16-7-4-8-18(10-16)32-13-17(30)12-29/h2-11,17,29-30H,1,12-13H2,(H,25,31)(H2,24,26,27,28)	IKTXZYPRPUOWTG-UHFFFAOYSA-N	397379	US9987276, Compound I-339::US10596172, Compound I-339::US10828300, Compound I-339::US11351168, Compound I-339	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397379&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174614	405267439							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794150	Fc1cnc(Nc2ccc(Cl)c(O[C@@H]3CCOC3)c2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C23H21ClFN5O3/c1-2-21(31)27-14-4-3-5-15(10-14)28-22-19(25)12-26-23(30-22)29-16-6-7-18(24)20(11-16)33-17-8-9-32-13-17/h2-7,10-12,17H,1,8-9,13H2,(H,27,31)(H2,26,28,29,30)	ITCAPRQOBQUQMI-UHFFFAOYSA-N	397380	US9987276, Compound I-341::US10596172, Compound I-341::US10828300, Compound I-341::US11351168, Compound I-341	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397380&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174407	405267440							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794151	CNC(=O)c1cc(Oc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc2)ccn1	InChI=1S/C26H22FN7O3/c1-3-23(35)31-17-5-4-6-18(13-17)32-24-21(27)15-30-26(34-24)33-16-7-9-19(10-8-16)37-20-11-12-29-22(14-20)25(36)28-2/h3-15H,1H2,2H3,(H,28,36)(H,31,35)(H2,30,32,33,34)	VVLHQJDAUIPZFH-UHFFFAOYSA-N	50403056	CHEMBL2216827::US9987276, Compound I-342::US10596172, Compound I-342::US10828300, Compound I-342::US11351168, Compound I-342	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403056&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174579	163352080		CHEMBL2216827					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794152	Fc1cnc(Nc2ccc3OCCN(C(=O)C=C)c3c2)nc1Nc1ccc(OCc2ccccn2)c(Cl)c1	InChI=1S/C27H22ClFN6O3/c1-2-25(36)35-11-12-37-24-9-7-18(14-22(24)35)33-27-31-15-21(29)26(34-27)32-17-6-8-23(20(28)13-17)38-16-19-5-3-4-10-30-19/h2-10,13-15H,1,11-12,16H2,(H2,31,32,33,34)	PWYIKLPJEMQGTI-UHFFFAOYSA-N	397381	US9987276, Compound I-343::US10596172, Compound I-343::US10828300, Compound I-343::US11351168, Compound I-343	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397381&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174523	405267441							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794153	COCCOc1ccc(Nc2ncc(F)c(N[C@@H]3CCCN(C3)C(=O)C=C)n2)cc1F |r|	InChI=1S/C21H25F2N5O3/c1-3-19(29)28-8-4-5-15(13-28)25-20-17(23)12-24-21(27-20)26-14-6-7-18(16(22)11-14)31-10-9-30-2/h3,6-7,11-12,15H,1,4-5,8-10,13H2,2H3,(H2,24,25,26,27)	GHENXVNLXTUAIN-UHFFFAOYSA-N	397382	US9987276, Compound I-344::US10596172, Compound I-344::US10828300, Compound I-344::US11351168, Compound I-344	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397382&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174363	405267442							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794154	COCCOc1ccc(Nc2ncc(F)c(N[C@@H]3CCCN(C3)C(=O)C=C)n2)cc1 |r|	InChI=1S/C21H26FN5O3/c1-3-19(28)27-10-4-5-16(14-27)24-20-18(22)13-23-21(26-20)25-15-6-8-17(9-7-15)30-12-11-29-2/h3,6-9,13,16H,1,4-5,10-12,14H2,2H3,(H2,23,24,25,26)	VDJZJUBHKHNNHT-UHFFFAOYSA-N	397383	US9987276, Compound I-345::US10596172, Compound I-345::US10828300, Compound I-345::US11351168, Compound I-345	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397383&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174613	405267443							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794155	Fc1cnc(Nc2ccc(Oc3cccnc3)cc2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C24H19FN6O2/c1-2-22(32)28-17-5-3-6-18(13-17)29-23-21(25)15-27-24(31-23)30-16-8-10-19(11-9-16)33-20-7-4-12-26-14-20/h2-15H,1H2,(H,28,32)(H2,27,29,30,31)	GGEOYJGWHQNNHP-UHFFFAOYSA-N	397384	US9987276, Compound I-346::US10596172, Compound I-346::US10828300, Compound I-346::US11351168, Compound I-346	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397384&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174497	405267444							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794156	Fc1cnc(Nc2ccc(O[C@H]3CCOC3)cc2)nc1N[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C22H26FN5O3/c1-2-20(29)28-10-3-4-16(13-28)25-21-19(23)12-24-22(27-21)26-15-5-7-17(8-6-15)31-18-9-11-30-14-18/h2,5-8,12,16,18H,1,3-4,9-11,13-14H2,(H2,24,25,26,27)	RFABWQVFHMNBMU-UHFFFAOYSA-N	397385	US9987276, Compound I-347::US10596172, Compound I-347::US10828300, Compound I-347	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397385&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174310	405267445							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794157	Fc1cnc(Nc2ccc(O[C@@H]3CCOC3)cc2)nc1N[C@@H]1CCCN(C1)C(=O)C=C |r|	InChI=1S/C22H26FN5O3/c1-2-20(29)28-10-3-4-16(13-28)25-21-19(23)12-24-22(27-21)26-15-5-7-17(8-6-15)31-18-9-11-30-14-18/h2,5-8,12,16,18H,1,3-4,9-11,13-14H2,(H2,24,25,26,27)	RFABWQVFHMNBMU-UHFFFAOYSA-N	397386	US9987276, Compound I-348::US10596172, Compound I-348::US10828300, Compound I-348::US11351168, Compound I-348	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397386&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174369	405267446							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794158	Fc1cnc(Nc2ccc3OCCOc3c2)nc1Nc1cccc(NC(=O)C=C)c1	InChI=1S/C21H18FN5O3/c1-2-19(28)24-13-4-3-5-14(10-13)25-20-16(22)12-23-21(27-20)26-15-6-7-17-18(11-15)30-9-8-29-17/h2-7,10-12H,1,8-9H2,(H,24,28)(H2,23,25,26,27)	CNOAVCCNAVGCOM-UHFFFAOYSA-N	397387	US9987276, Compound I-349::US10596172, Compound I-349::US10828300, Compound I-349::US11351168, Compound I-349	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397387&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174325	405267447							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794159	COCCOc1ccc(Nc2ncc(C#N)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C23H21FN6O3/c1-3-21(31)27-16-5-4-6-17(11-16)28-22-15(13-25)14-26-23(30-22)29-18-7-8-20(19(24)12-18)33-10-9-32-2/h3-8,11-12,14H,1,9-10H2,2H3,(H,27,31)(H2,26,28,29,30)	MJHIJTUJSQAPEZ-UHFFFAOYSA-N	397388	US9987276, Compound I-350::US10596172, Compound I-350::US10828300, Compound I-350::US11351168, Compound I-350	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397388	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397388&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174370	405267448							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794160	COCCOc1ccc(Nc2ncc(F)c(Nc3ccc(NC(=O)C=C)cc3)n2)cc1F	InChI=1S/C22H21F2N5O3/c1-3-20(30)26-14-4-6-15(7-5-14)27-21-18(24)13-25-22(29-21)28-16-8-9-19(17(23)12-16)32-11-10-31-2/h3-9,12-13H,1,10-11H2,2H3,(H,26,30)(H2,25,27,28,29)	ANIJZPVCHRFHTD-UHFFFAOYSA-N	397389	US9987276, Compound I-351::US10596172, Compound I-351::US10828300, Compound I-351::US11351168, Compound I-351	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397389&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174786	405267449							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794161	COCCOc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)cc1F	InChI=1S/C23H21F4N5O3/c1-3-20(33)29-14-5-4-6-15(11-14)30-21-17(23(25,26)27)13-28-22(32-21)31-16-7-8-19(18(24)12-16)35-10-9-34-2/h3-8,11-13H,1,9-10H2,2H3,(H,29,33)(H2,28,30,31,32)	OQBBGURULCSGNH-UHFFFAOYSA-N	397390	US9987276, Compound I-352::US10596172, Compound I-352::US10828300, Compound I-352::US11351168, Compound I-352	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397390	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397390&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174634	405267450							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794162	OCC(O)COc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl	InChI=1S/C22H21ClFN5O4/c1-2-20(32)26-13-4-3-5-14(8-13)27-21-18(24)10-25-22(29-21)28-15-6-7-17(23)19(9-15)33-12-16(31)11-30/h2-10,16,30-31H,1,11-12H2,(H,26,32)(H2,25,27,28,29)	DHVUCAZYIPVMMP-UHFFFAOYSA-N	397281	US9987276, Compound I-353::US10596172, Compound I-353::US10828300, Compound I-353::US11351168, Compound I-353	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397281	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397281&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174423	405267346							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794163	Fc1cnc(Nc2ccc(Cl)c(O[C@H]3CCOC3)c2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C23H21ClFN5O3/c1-2-21(31)27-14-4-3-5-15(10-14)28-22-19(25)12-26-23(30-22)29-16-6-7-18(24)20(11-16)33-17-8-9-32-13-17/h2-7,10-12,17H,1,8-9,13H2,(H,27,31)(H2,26,28,29,30)	ITCAPRQOBQUQMI-UHFFFAOYSA-N	397282	US9987276, Compound I-354::US10596172, Compound I-354::US10828300, Compound I-354::US11351168, Compound I-354	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397282	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397282&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174490	405267347							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794164	O[C@H]1CN[C@H](COc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc2F)C1 |r|	InChI=1S/C24H24F2N6O3/c1-2-22(34)29-14-4-3-5-15(8-14)30-23-20(26)12-28-24(32-23)31-16-6-7-21(19(25)10-16)35-13-17-9-18(33)11-27-17/h2-8,10,12,17-18,27,33H,1,9,11,13H2,(H,29,34)(H2,28,30,31,32)	BJONHSCXBJYULE-UHFFFAOYSA-N	397283	US9987276, Compound I-355::US10596172, Compound I-355::US10828300, Compound I-355::US11351168, Compound I-355	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397283	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397283&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174698	405267348							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794165	CC(C)(C)OC(=O)NCCOCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C28H32F2N6O5/c1-5-24(37)33-18-7-6-8-19(15-18)34-25-22(30)17-32-26(36-25)35-20-9-10-23(21(29)16-20)40-14-13-39-12-11-31-27(38)41-28(2,3)4/h5-10,15-17H,1,11-14H2,2-4H3,(H,31,38)(H,33,37)(H2,32,34,35,36)	XBOASQDXYQLAHV-UHFFFAOYSA-N	397284	US9987276, Compound I-356::US10596172, Compound I-356::US10828300, Compound I-356::US11351168, Compound I-356	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397284	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397284&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174400	405267349							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794166	C[C@@H](CO)Oc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl |r|	InChI=1S/C22H21ClFN5O3/c1-3-20(31)26-14-5-4-6-15(9-14)27-21-18(24)11-25-22(29-21)28-16-7-8-17(23)19(10-16)32-13(2)12-30/h3-11,13,30H,1,12H2,2H3,(H,26,31)(H2,25,27,28,29)	VZXXRAOOPZBUJW-UHFFFAOYSA-N	397285	US9987276, Compound I-357::US10596172, Compound I-357::US10828300, Compound I-357::US11351168, Compound I-357	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397285	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397285&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174335	405267350							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794167	C[C@H](CO)Oc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl |r|	InChI=1S/C22H21ClFN5O3/c1-3-20(31)26-14-5-4-6-15(9-14)27-21-18(24)11-25-22(29-21)28-16-7-8-17(23)19(10-16)32-13(2)12-30/h3-11,13,30H,1,12H2,2H3,(H,26,31)(H2,25,27,28,29)	VZXXRAOOPZBUJW-UHFFFAOYSA-N	397391	US9987276, Compound I-358::US10596172, Compound I-358::US10828300, Compound I-358::US11351168, Compound I-358	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397391	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397391&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174528	405267451							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794168	COCCOCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F	InChI=1S/C24H25F2N5O4/c1-3-22(32)28-16-5-4-6-17(13-16)29-23-20(26)15-27-24(31-23)30-18-7-8-21(19(25)14-18)35-12-11-34-10-9-33-2/h3-8,13-15H,1,9-12H2,2H3,(H,28,32)(H2,27,29,30,31)	XYXBANPJPSZIPD-UHFFFAOYSA-N	397286	US9987276, Compound I-359::US10596172, Compound I-359::US10828300, Compound I-359::US11351168, Compound I-359	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397286	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397286&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174624	405267351							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794169	CN(C)C\C=C\C(=O)Nc1cccc(Nc2ncc(F)c(Nc3cccc(C)c3)n2)c1	InChI=1S/C23H25FN6O/c1-16-7-4-8-17(13-16)27-22-20(24)15-25-23(29-22)28-19-10-5-9-18(14-19)26-21(31)11-6-12-30(2)3/h4-11,13-15H,12H2,1-3H3,(H,26,31)(H2,25,27,28,29)	QHBQTYVTHVMJKQ-UHFFFAOYSA-N	397144	US9987276, Compound I-4::US9987276, Compound I-360::US10596172, Compound I-4::US10828300, Compound I-4::US11351168, Compound I-4	Epidermal growth factor receptor	Homo sapiens		<10							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397144	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397144&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			44596109	405267212							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
794170	Fc1cnc(Nc2ccc(OCCOCCNC(=O)CCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)c(F)c2)nc1Nc1cccc(NC(=O)C=C)c1 |r|	InChI=1S/C48H66F2N10O10S/c1-2-41(61)55-33-9-5-10-34(29-33)56-46-37(50)31-54-47(60-46)57-35-15-16-39(36(49)30-35)70-28-27-68-22-19-53-44(64)14-6-13-43(63)52-18-8-21-67-24-26-69-25-23-66-20-7-17-51-42(62)12-4-3-11-40-45-38(32-71-40)58-48(65)59-45/h2,5,9-10,15-16,29-31,38,40,45H,1,3-4,6-8,11-14,17-28,32H2,(H,51,62)(H,52,63)(H,53,64)(H,55,61)(H2,58,59,65)(H2,54,56,57,60)	YPCIIDALYPYOIV-UHFFFAOYSA-N	397287	US9987276, Compound I-362::US10596172, Compound I-362::US10828300, Compound I-362::US11351168, Compound I-362	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2NV9MM2		aid1799141	US9987276	Singh, J; Petter, RC; Tester, RW; Kluge, AF; Mazdiyasni, H; Westlin, III, WF; Niu, D; Qiao, L	6/5/2018	4/25/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=397287	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=397287&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			59174651	405267352							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823149	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H26N6O2/c1-33-20-9-5-4-8-19(20)25(32)27-14-16-10-12-17(13-11-16)22-21-23(26)28-15-29-24(21)31(30-22)18-6-2-3-7-18/h4-5,8-13,15,18H,2-3,6-7,14H2,1H3,(H,27,32)(H2,26,28,29)	JVJAMKKMPGSZJX-UHFFFAOYSA-N	412785	US10399989, Example 1::US10611766, Example 1	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412785&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823151	Nc1ncnc2n(nc(-c3ccc(CNC(=O)c4ccccc4F)cc3)c12)C1CCCC1	InChI=1S/C24H23FN6O/c25-19-8-4-3-7-18(19)24(32)27-13-15-9-11-16(12-10-15)21-20-22(26)28-14-29-23(20)31(30-21)17-5-1-2-6-17/h3-4,7-12,14,17H,1-2,5-6,13H2,(H,27,32)(H2,26,28,29)	FTDGXRLGVYGRMH-UHFFFAOYSA-N	412786	US10399989, Example 2::US10611766, Example 2	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412786&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823155	COc1ccc(F)cc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H25FN6O2/c1-34-20-11-10-17(26)12-19(20)25(33)28-13-15-6-8-16(9-7-15)22-21-23(27)29-14-30-24(21)32(31-22)18-4-2-3-5-18/h6-12,14,18H,2-5,13H2,1H3,(H,28,33)(H2,27,29,30)	OELQBKVEOCTGBX-UHFFFAOYSA-N	412788	US10399989, Example 4::N-[[4-(4-amino-1-cyclopentyl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]methyl]-5-fluoro-2-methoxy-benzamide::US10611766, Example 4	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412788	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412788&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823158	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCO2)c2ncnc(N)c12	InChI=1S/C24H24N6O3/c1-32-18-6-3-2-5-17(18)24(31)26-13-15-8-10-16(11-9-15)21-20-22(25)27-14-28-23(20)30(29-21)19-7-4-12-33-19/h2-3,5-6,8-11,14,19H,4,7,12-13H2,1H3,(H,26,31)(H2,25,27,28)	WWCBVSVBXMQVEP-UHFFFAOYSA-N	412789	US10399989, Example 5::US10611766, Example 5	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412789&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823160	Nc1ncnc2n(nc(-c3ccc(CNC(=O)c4ccccc4OC(F)(F)F)cc3)c12)C1CCCC1	InChI=1S/C25H23F3N6O2/c26-25(27,28)36-19-8-4-3-7-18(19)24(35)30-13-15-9-11-16(12-10-15)21-20-22(29)31-14-32-23(20)34(33-21)17-5-1-2-6-17/h3-4,7-12,14,17H,1-2,5-6,13H2,(H,30,35)(H2,29,31,32)	LFJPRKPBZVVZQV-UHFFFAOYSA-N	412790	US10399989, Example 6::US10611766, Example 6	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412790	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412790&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823163	CCOc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-2-34-21-10-6-5-9-20(21)26(33)28-15-17-11-13-18(14-12-17)23-22-24(27)29-16-30-25(22)32(31-23)19-7-3-4-8-19/h5-6,9-14,16,19H,2-4,7-8,15H2,1H3,(H,28,33)(H2,27,29,30)	ZEKVNOOBJNGEGS-UHFFFAOYSA-N	412791	US10399989, Example 7::US10611766, Example 7	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412791&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823166	CC(C)Oc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C27H30N6O2/c1-17(2)35-22-10-6-5-9-21(22)27(34)29-15-18-11-13-19(14-12-18)24-23-25(28)30-16-31-26(23)33(32-24)20-7-3-4-8-20/h5-6,9-14,16-17,20H,3-4,7-8,15H2,1-2H3,(H,29,34)(H2,28,30,31)	VQALIWXXIVOORF-UHFFFAOYSA-N	412792	US10399989, Example 8	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412792&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823168	COc1cc(Cl)ccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H25ClN6O2/c1-34-20-12-17(26)10-11-19(20)25(33)28-13-15-6-8-16(9-7-15)22-21-23(27)29-14-30-24(21)32(31-22)18-4-2-3-5-18/h6-12,14,18H,2-5,13H2,1H3,(H,28,33)(H2,27,29,30)	TVMLHCWUWADBEV-UHFFFAOYSA-N	412793	US10399989, Example 9::US10611766, Example 9	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412793	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412793&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823170	COc1cc(C)ccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-16-7-12-20(21(13-16)34-2)26(33)28-14-17-8-10-18(11-9-17)23-22-24(27)29-15-30-25(22)32(31-23)19-5-3-4-6-19/h7-13,15,19H,3-6,14H2,1-2H3,(H,28,33)(H2,27,29,30)	TXZOUKZTBPYPHC-UHFFFAOYSA-N	412794	US10399989, Example 10::US10611766, Example 10	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412794&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823173	COc1ccc(Cl)cc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H25ClN6O2/c1-34-20-11-10-17(26)12-19(20)25(33)28-13-15-6-8-16(9-7-15)22-21-23(27)29-14-30-24(21)32(31-22)18-4-2-3-5-18/h6-12,14,18H,2-5,13H2,1H3,(H,28,33)(H2,27,29,30)	NGHRMNXTWYBWHM-UHFFFAOYSA-N	412795	US10399989, Example 11::US10611766, Example 11	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412795&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823176	COc1ccc(C)cc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-16-7-12-21(34-2)20(13-16)26(33)28-14-17-8-10-18(11-9-17)23-22-24(27)29-15-30-25(22)32(31-23)19-5-3-4-6-19/h7-13,15,19H,3-6,14H2,1-2H3,(H,28,33)(H2,27,29,30)	TXSHMSAAJVATEA-UHFFFAOYSA-N	412796	US10399989, Example 12::US10611766, Example 12	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412796&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823178	COc1ccc(cc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12)C(F)(F)F	InChI=1S/C26H25F3N6O2/c1-37-20-11-10-17(26(27,28)29)12-19(20)25(36)31-13-15-6-8-16(9-7-15)22-21-23(30)32-14-33-24(21)35(34-22)18-4-2-3-5-18/h6-12,14,18H,2-5,13H2,1H3,(H,31,36)(H2,30,32,33)	DXWXQECOOLXJHF-UHFFFAOYSA-N	412798	US10399989, Example 13::US10611766, Example 13	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412798&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823180	COc1c(F)cccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H25FN6O2/c1-34-22-18(7-4-8-19(22)26)25(33)28-13-15-9-11-16(12-10-15)21-20-23(27)29-14-30-24(20)32(31-21)17-5-2-3-6-17/h4,7-12,14,17H,2-3,5-6,13H2,1H3,(H,28,33)(H2,27,29,30)	HFTCWQMJXWAUAN-UHFFFAOYSA-N	412799	US10399989, Example 14::US10611766, Example 14	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412799&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823182	COc1cc(F)ccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H25FN6O2/c1-34-20-12-17(26)10-11-19(20)25(33)28-13-15-6-8-16(9-7-15)22-21-23(27)29-14-30-24(21)32(31-22)18-4-2-3-5-18/h6-12,14,18H,2-5,13H2,1H3,(H,28,33)(H2,27,29,30)	ZQVHUCQNAUTGDD-UHFFFAOYSA-N	412800	US10399989, Example 15::US10611766, Example 15	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412800&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823184	COc1cccc(F)c1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H25FN6O2/c1-34-19-8-4-7-18(26)20(19)25(33)28-13-15-9-11-16(12-10-15)22-21-23(27)29-14-30-24(21)32(31-22)17-5-2-3-6-17/h4,7-12,14,17H,2-3,5-6,13H2,1H3,(H,28,33)(H2,27,29,30)	GKQRSPZVVNEONB-UHFFFAOYSA-N	412801	US10399989, Example 16::US10611766, Example 16	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412801&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823186	COc1ccccc1C(=O)N(C)Cc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-31(26(33)20-9-5-6-10-21(20)34-2)15-17-11-13-18(14-12-17)23-22-24(27)28-16-29-25(22)32(30-23)19-7-3-4-8-19/h5-6,9-14,16,19H,3-4,7-8,15H2,1-2H3,(H2,27,28,29)	XQJPFADJZWIRBA-UHFFFAOYSA-N	412802	US10399989, Example 17::US10611766, Example 17	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412802&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823189	COc1ncccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C24H25N7O2/c1-33-24-18(7-4-12-26-24)23(32)27-13-15-8-10-16(11-9-15)20-19-21(25)28-14-29-22(19)31(30-20)17-5-2-3-6-17/h4,7-12,14,17H,2-3,5-6,13H2,1H3,(H,27,32)(H2,25,28,29)	XJBOGMAXDOAFCH-UHFFFAOYSA-N	412803	US10399989, Example 18::US10611766, Example 18	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412803&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823192	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC3(CC2)OCCO3)c2ncnc(N)c12	InChI=1S/C28H30N6O4/c1-36-22-5-3-2-4-21(22)27(35)30-16-18-6-8-19(9-7-18)24-23-25(29)31-17-32-26(23)34(33-24)20-10-12-28(13-11-20)37-14-15-38-28/h2-9,17,20H,10-16H2,1H3,(H,30,35)(H2,29,31,32)	RIOGTLBVZWFTFU-UHFFFAOYSA-N	412804	US10399989, Example 19::US10611766, Example 19	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412804&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823194	Nc1ncnc2n(nc(-c3ccc(CNC(=O)c4cccc(c4)C#N)cc3)c12)C1CCCC1	InChI=1S/C25H23N7O/c26-13-17-4-3-5-19(12-17)25(33)28-14-16-8-10-18(11-9-16)22-21-23(27)29-15-30-24(21)32(31-22)20-6-1-2-7-20/h3-5,8-12,15,20H,1-2,6-7,14H2,(H,28,33)(H2,27,29,30)	XEPZBYPPIOVUTE-UHFFFAOYSA-N	412805	US10399989, Example 20::US10611766, Example 20	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412805&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823197	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(=O)C2)c2ncnc(N)c12	InChI=1S/C25H24N6O3/c1-34-20-5-3-2-4-19(20)25(33)27-13-15-6-8-16(9-7-15)22-21-23(26)28-14-29-24(21)31(30-22)17-10-11-18(32)12-17/h2-9,14,17H,10-13H2,1H3,(H,27,33)(H2,26,28,29)	WBWCDSIUSDPATH-UHFFFAOYSA-N	412806	US10399989, Example 21::US10611766, Example 21	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412806&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823199	COc1c(C)cccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-16-6-5-9-20(23(16)34-2)26(33)28-14-17-10-12-18(13-11-17)22-21-24(27)29-15-30-25(21)32(31-22)19-7-3-4-8-19/h5-6,9-13,15,19H,3-4,7-8,14H2,1-2H3,(H,28,33)(H2,27,29,30)	UBMDHWMFMHXDEX-UHFFFAOYSA-N	412807	US10399989, Example 22::US10611766, Example 22	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412807&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823202	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(O)CC2)c2ncnc(N)c12 |(3.02,11.02,;2.37,9.63,;3.46,8.54,;4.95,8.94,;6.04,7.85,;5.64,6.36,;4.15,5.96,;3.06,7.05,;1.57,6.65,;.49,7.74,;1.18,5.16,;-.31,4.77,;-.71,3.28,;.38,2.19,;-.02,.7,;-1.51,.3,;-2.6,1.39,;-2.2,2.88,;-1.91,-1.18,;-1,-2.43,;-1.91,-3.68,;-1.51,-5.16,;-2.6,-6.25,;-2.2,-7.74,;-.71,-8.14,;-.31,-9.63,;.38,-7.05,;-.02,-5.56,;-3.37,-3.2,;-4.7,-3.97,;-6.04,-3.2,;-6.04,-1.66,;-4.7,-.89,;-4.7,.65,;-3.37,-1.66,)|	InChI=1S/C26H28N6O3/c1-35-21-5-3-2-4-20(21)26(34)28-14-16-6-8-17(9-7-16)23-22-24(27)29-15-30-25(22)32(31-23)18-10-12-19(33)13-11-18/h2-9,15,18-19,33H,10-14H2,1H3,(H,28,34)(H2,27,29,30)	BKYSCRZQLODSDO-UHFFFAOYSA-N	412808	US10399989, Example 23-isomer2::US10399989, Example 23-isomer1	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412808&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823205	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(O)CC2)c2ncnc(N)c12 |(3.02,11.02,;2.37,9.63,;3.46,8.54,;4.95,8.94,;6.04,7.85,;5.64,6.36,;4.15,5.96,;3.06,7.05,;1.57,6.65,;.49,7.74,;1.18,5.16,;-.31,4.77,;-.71,3.28,;.38,2.19,;-.02,.7,;-1.51,.3,;-2.6,1.39,;-2.2,2.88,;-1.91,-1.18,;-1,-2.43,;-1.91,-3.68,;-1.51,-5.16,;-2.6,-6.25,;-2.2,-7.74,;-.71,-8.14,;-.31,-9.63,;.38,-7.05,;-.02,-5.56,;-3.37,-3.2,;-4.7,-3.97,;-6.04,-3.2,;-6.04,-1.66,;-4.7,-.89,;-4.7,.65,;-3.37,-1.66,)|	InChI=1S/C26H28N6O3/c1-35-21-5-3-2-4-20(21)26(34)28-14-16-6-8-17(9-7-16)23-22-24(27)29-15-30-25(22)32(31-23)18-10-12-19(33)13-11-18/h2-9,15,18-19,33H,10-14H2,1H3,(H,28,34)(H2,27,29,30)	BKYSCRZQLODSDO-UHFFFAOYSA-N	412808	US10399989, Example 23-isomer2::US10399989, Example 23-isomer1	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412808&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823208	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2CC[C@H](O)C2)c2ncnc(N)c12 |r|	InChI=1S/C25H26N6O3/c1-34-20-5-3-2-4-19(20)25(33)27-13-15-6-8-16(9-7-15)22-21-23(26)28-14-29-24(21)31(30-22)17-10-11-18(32)12-17/h2-9,14,17-18,32H,10-13H2,1H3,(H,27,33)(H2,26,28,29)	KANCPYQDKMNODD-UHFFFAOYSA-N	412810	US10399989, Example 24::N-[[4-[4-amino-1-[(1R*,3S*)-3-hydroxycyclopentyl]pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 24	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823211	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC3(C2)OCCO3)c2ncnc(N)c12	InChI=1S/C27H28N6O4/c1-35-21-5-3-2-4-20(21)26(34)29-15-17-6-8-18(9-7-17)23-22-24(28)30-16-31-25(22)33(32-23)19-10-11-27(14-19)36-12-13-37-27/h2-9,16,19H,10-15H2,1H3,(H,29,34)(H2,28,30,31)	CPMAFVDAGIOEIE-UHFFFAOYSA-N	412811	US10399989, Example 25::US10611766, Example 25	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412811&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823214	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(=O)CC2)c2ncnc(N)c12	InChI=1S/C26H26N6O3/c1-35-21-5-3-2-4-20(21)26(34)28-14-16-6-8-17(9-7-16)23-22-24(27)29-15-30-25(22)32(31-23)18-10-12-19(33)13-11-18/h2-9,15,18H,10-14H2,1H3,(H,28,34)(H2,27,29,30)	QCJLXNNOYQGLAZ-UHFFFAOYSA-N	412812	US10399989, Example 26::US10611766, Example 26	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412812&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823217	COc1ccncc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C24H25N7O2/c1-33-19-10-11-26-13-18(19)24(32)27-12-15-6-8-16(9-7-15)21-20-22(25)28-14-29-23(20)31(30-21)17-4-2-3-5-17/h6-11,13-14,17H,2-5,12H2,1H3,(H,27,32)(H2,25,28,29)	QTYWKDXYFWPUSY-UHFFFAOYSA-N	412813	US10399989, Example 27::US10611766, Example 27	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412813&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823220	CNC1CCC(CC1)n1nc(-c2ccc(CNC(=O)c3ccccc3OC)cc2)c2c(N)ncnc12 |(1.19,-9.88,;-.3,-9.48,;-.7,-7.99,;-2.2,-7.54,;-2.6,-6.05,;-1.51,-4.96,;-.02,-5.36,;.38,-6.85,;-1.91,-3.48,;-1,-2.23,;-1.91,-.99,;-1.51,.5,;-.02,.9,;.38,2.39,;-.71,3.48,;-.31,4.96,;1.18,5.36,;1.57,6.85,;.49,7.94,;3.06,7.25,;4.15,6.16,;5.64,6.56,;6.04,8.05,;4.95,9.14,;3.46,8.74,;2.37,9.83,;3.02,11.22,;-2.2,3.08,;-2.6,1.59,;-3.37,-1.46,;-4.7,-.69,;-4.7,.85,;-6.04,-1.46,;-6.04,-3,;-4.7,-3.77,;-3.37,-3,)|	InChI=1S/C27H31N7O2/c1-29-19-11-13-20(14-12-19)34-26-23(25(28)31-16-32-26)24(33-34)18-9-7-17(8-10-18)15-30-27(35)21-5-3-4-6-22(21)36-2/h3-10,16,19-20,29H,11-15H2,1-2H3,(H,30,35)(H2,28,31,32)	WUTKDWQWCRNCFZ-UHFFFAOYSA-N	412814	US10399989, Example 28::US10611766, Example 28	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412814&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823223	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCOCC2)c2ncnc(N)c12	InChI=1S/C25H26N6O3/c1-33-20-5-3-2-4-19(20)25(32)27-14-16-6-8-17(9-7-16)22-21-23(26)28-15-29-24(21)31(30-22)18-10-12-34-13-11-18/h2-9,15,18H,10-14H2,1H3,(H,27,32)(H2,26,28,29)	IOQJICCQMPGYPJ-UHFFFAOYSA-N	412815	US10399989, Example 29::US10611766, Example 29	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412815&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823226	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(CC2)C(O)=O)c2ncnc(N)c12 |(3.02,11.57,;2.37,10.17,;3.46,9.08,;4.95,9.48,;6.04,8.39,;5.64,6.9,;4.15,6.51,;3.06,7.59,;1.57,7.2,;.49,8.29,;1.18,5.71,;-.31,5.31,;-.71,3.82,;.38,2.73,;-.02,1.25,;-1.51,.85,;-2.6,1.94,;-2.2,3.42,;-1.91,-.64,;-1,-1.89,;-1.91,-3.13,;-1.51,-4.62,;-2.6,-5.71,;-2.2,-7.2,;-.71,-7.59,;.38,-6.51,;-.02,-5.02,;-.31,-9.08,;1.18,-9.48,;-1.4,-10.17,;-3.37,-2.66,;-4.7,-3.43,;-6.04,-2.66,;-6.04,-1.12,;-4.7,-.35,;-4.7,1.19,;-3.37,-1.12,)|	InChI=1S/C27H28N6O4/c1-37-21-5-3-2-4-20(21)26(34)29-14-16-6-8-17(9-7-16)23-22-24(28)30-15-31-25(22)33(32-23)19-12-10-18(11-13-19)27(35)36/h2-9,15,18-19H,10-14H2,1H3,(H,29,34)(H,35,36)(H2,28,30,31)	SBAYNVDRRWGWPC-UHFFFAOYSA-N	412816	US10399989, Example 30::N-[[4-[4-amino-1-[(1R,4R)-4-hydroxycyclopent-2-en-1-yl]pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 30	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412816&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823229	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC(=O)C2)c2ncnc(N)c12	InChI=1S/C26H26N6O3/c1-35-21-8-3-2-7-20(21)26(34)28-14-16-9-11-17(12-10-16)23-22-24(27)29-15-30-25(22)32(31-23)18-5-4-6-19(33)13-18/h2-3,7-12,15,18H,4-6,13-14H2,1H3,(H,28,34)(H2,27,29,30)	MGNXPFKSTNWIMZ-UHFFFAOYSA-N	412817	US10399989, Example 31::US10611766, Example 31	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412817&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823232	CCOC(=O)C1CCC(CC1)n1nc(-c2ccc(CNC(=O)c3ccccc3OC)cc2)c2c(N)ncnc12 |(-.72,-13,;-1.75,-11.86,;-1.28,-10.39,;-2.31,-9.25,;-3.81,-9.57,;-1.83,-7.78,;-.32,-7.46,;.15,-6,;-.88,-4.85,;-2.38,-5.17,;-2.86,-6.64,;-.4,-3.39,;-1.31,-2.14,;-.4,-.9,;-.88,.57,;-2.38,.89,;-2.86,2.35,;-1.83,3.5,;-2.31,4.96,;-1.28,6.11,;-1.75,7.57,;-3.26,7.89,;-.72,8.71,;-1.2,10.18,;-.17,11.32,;1.34,11,;1.82,9.54,;.79,8.39,;1.26,6.93,;.05,5.98,;-.32,3.18,;.15,1.71,;1.06,-1.37,;2.4,-.6,;2.4,.94,;3.73,-1.37,;3.73,-2.91,;2.4,-3.68,;1.06,-2.91,)|	InChI=1S/C29H32N6O4/c1-3-39-29(37)20-12-14-21(15-13-20)35-27-24(26(30)32-17-33-27)25(34-35)19-10-8-18(9-11-19)16-31-28(36)22-6-4-5-7-23(22)38-2/h4-11,17,20-21H,3,12-16H2,1-2H3,(H,31,36)(H2,30,32,33)	VKLJPCKYIPLXHW-UHFFFAOYSA-N	412818	US10399989, Example 32::US10611766, Example 32	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412818&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823235	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@H]2CC[C@@H](CC2)C(=O)N(C)C)c2ncnc(N)c12 |r,wU:24.29,wD:21.22,(.27,6.33,;1.48,7.28,;1.01,8.75,;2.04,9.89,;1.56,11.36,;.06,11.68,;-.97,10.53,;-.5,9.07,;-1.53,7.92,;-3.04,8.24,;-1.05,6.46,;-2.08,5.31,;-1.61,3.85,;-2.64,2.7,;-2.16,1.24,;-.66,.92,;.37,2.06,;-.1,3.53,;-.18,-.55,;-1.09,-1.79,;-.18,-3.04,;-.66,-4.5,;-2.16,-4.82,;-2.64,-6.29,;-1.61,-7.43,;-.1,-7.11,;.37,-5.65,;-2.08,-8.9,;-1.05,-10.04,;-3.59,-9.22,;-4.07,-10.68,;-4.62,-8.07,;1.28,-2.56,;2.62,-3.33,;3.95,-2.56,;3.95,-1.02,;2.62,-.25,;2.62,1.29,;1.28,-1.02,)|	InChI=1S/C29H33N7O3/c1-35(2)29(38)20-12-14-21(15-13-20)36-27-24(26(30)32-17-33-27)25(34-36)19-10-8-18(9-11-19)16-31-28(37)22-6-4-5-7-23(22)39-3/h4-11,17,20-21H,12-16H2,1-3H3,(H,31,37)(H2,30,32,33)	QMPVOKLNLZCVBG-UHFFFAOYSA-N	412819	US10399989, Example 33-isomer 1	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412819&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823238	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2CC[C@@H](CC2)C(=O)N(C)C)c2ncnc(N)c12 |r,wU:21.22,24.29,(.27,6.33,;1.48,7.28,;1.01,8.75,;2.04,9.89,;1.56,11.36,;.06,11.68,;-.97,10.53,;-.5,9.07,;-1.53,7.92,;-3.04,8.24,;-1.05,6.46,;-2.08,5.31,;-1.61,3.85,;-2.64,2.7,;-2.16,1.24,;-.66,.92,;.37,2.06,;-.1,3.53,;-.18,-.55,;-1.09,-1.79,;-.18,-3.04,;-.66,-4.5,;-2.16,-4.82,;-2.64,-6.29,;-1.61,-7.43,;-.1,-7.11,;.37,-5.65,;-2.08,-8.9,;-1.05,-10.04,;-3.59,-9.22,;-4.07,-10.68,;-4.62,-8.07,;1.28,-2.56,;2.62,-3.33,;3.95,-2.56,;3.95,-1.02,;2.62,-.25,;2.62,1.29,;1.28,-1.02,)|	InChI=1S/C29H33N7O3/c1-35(2)29(38)20-12-14-21(15-13-20)36-27-24(26(30)32-17-33-27)25(34-36)19-10-8-18(9-11-19)16-31-28(37)22-6-4-5-7-23(22)39-3/h4-11,17,20-21H,12-16H2,1-3H3,(H,31,37)(H2,30,32,33)	QMPVOKLNLZCVBG-UHFFFAOYSA-N	412820	US10399989, Example 33-isomer 2::US10611766, Example 33-isomer 2	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412820&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823241	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2CC[C@@H](CC2)C(=O)N(C)C)c2ncnc(N)c12 |r,wU:21.22,24.29,(.27,6.33,;1.48,7.28,;1.01,8.75,;2.04,9.89,;1.56,11.36,;.06,11.68,;-.97,10.53,;-.5,9.07,;-1.53,7.92,;-3.04,8.24,;-1.05,6.46,;-2.08,5.31,;-1.61,3.85,;-2.64,2.7,;-2.16,1.24,;-.66,.92,;.37,2.06,;-.1,3.53,;-.18,-.55,;-1.09,-1.79,;-.18,-3.04,;-.66,-4.5,;-2.16,-4.82,;-2.64,-6.29,;-1.61,-7.43,;-.1,-7.11,;.37,-5.65,;-2.08,-8.9,;-1.05,-10.04,;-3.59,-9.22,;-4.07,-10.68,;-4.62,-8.07,;1.28,-2.56,;2.62,-3.33,;3.95,-2.56,;3.95,-1.02,;2.62,-.25,;2.62,1.29,;1.28,-1.02,)|	InChI=1S/C29H33N7O3/c1-35(2)29(38)20-12-14-21(15-13-20)36-27-24(26(30)32-17-33-27)25(34-36)19-10-8-18(9-11-19)16-31-28(37)22-6-4-5-7-23(22)39-3/h4-11,17,20-21H,12-16H2,1-3H3,(H,31,37)(H2,30,32,33)	QMPVOKLNLZCVBG-UHFFFAOYSA-N	412820	US10399989, Example 33-isomer 2::US10611766, Example 33-isomer 2	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412820&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823244	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCOC2)c2ncnc(N)c12	InChI=1S/C25H26N6O3/c1-33-20-7-3-2-6-19(20)25(32)27-13-16-8-10-17(11-9-16)22-21-23(26)28-15-29-24(21)31(30-22)18-5-4-12-34-14-18/h2-3,6-11,15,18H,4-5,12-14H2,1H3,(H,27,32)(H2,26,28,29)	AIEKFOIDSJRXNN-UHFFFAOYSA-N	412821	US10399989, Example 34::US10611766, Example 34	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412821&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823247	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@@H](OC(C)=O)C=C2)c2ncnc(N)c12 |r,c:30|	InChI=1S/C27H26N6O4/c1-16(34)37-20-12-11-19(13-20)33-26-23(25(28)30-15-31-26)24(32-33)18-9-7-17(8-10-18)14-29-27(35)21-5-3-4-6-22(21)36-2/h3-12,15,19-20H,13-14H2,1-2H3,(H,29,35)(H2,28,30,31)	YDIGJTWKIDVGIP-UHFFFAOYSA-N	412822	US10399989, Example 35::US10611766, Example 35	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412822&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823250	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@@H](O)C=C2)c2ncnc(N)c12 |r,c:27|	InChI=1S/C25H24N6O3/c1-34-20-5-3-2-4-19(20)25(33)27-13-15-6-8-16(9-7-15)22-21-23(26)28-14-29-24(21)31(30-22)17-10-11-18(32)12-17/h2-11,14,17-18,32H,12-13H2,1H3,(H,27,33)(H2,26,28,29)	MPYBIRVGTIQZJU-UHFFFAOYSA-N	412823	US10399989, Example 36::US10611766, Example 36	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412823&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823253	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC(O)C2)c2ncnc(N)c12	InChI=1S/C26H28N6O3/c1-35-21-8-3-2-7-20(21)26(34)28-14-16-9-11-17(12-10-16)23-22-24(27)29-15-30-25(22)32(31-23)18-5-4-6-19(33)13-18/h2-3,7-12,15,18-19,33H,4-6,13-14H2,1H3,(H,28,34)(H2,27,29,30)	CEDHECFLEQREKN-UHFFFAOYSA-N	412824	US10399989, Example 37::N-[[4-[4-amino-1-(3-hydroxycyclohexyl)pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 37	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412824&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823256	COc1ccccc1C(=O)NCc1ccc(cc1)-n1nc(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H26N6O2/c1-33-20-9-5-4-8-19(20)25(32)27-14-16-10-12-18(13-11-16)31-23-22(28-15-29-24(23)26)21(30-31)17-6-2-3-7-17/h4-5,8-13,15,17H,2-3,6-7,14H2,1H3,(H,27,32)(H2,26,28,29)	YKNZRLLQSHZKFO-UHFFFAOYSA-N	412825	US10399989, Example 38::US10611766, Example 38	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412825&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823259	COC1CCC(CC1)n1nc(-c2ccc(CNC(=O)c3ccccc3OC)cc2)c2c(N)ncnc12 |(1.19,-9.88,;-.3,-9.48,;-.7,-7.99,;-2.2,-7.54,;-2.6,-6.05,;-1.51,-4.96,;-.02,-5.36,;.38,-6.85,;-1.91,-3.48,;-1,-2.23,;-1.91,-.99,;-1.51,.5,;-.02,.9,;.38,2.39,;-.71,3.48,;-.31,4.96,;1.18,5.36,;1.57,6.85,;.49,7.94,;3.06,7.25,;4.15,6.16,;5.64,6.56,;6.04,8.05,;4.95,9.14,;3.46,8.74,;2.37,9.83,;3.02,11.22,;-2.2,3.08,;-2.6,1.59,;-3.37,-1.46,;-4.7,-.69,;-4.7,.85,;-6.04,-1.46,;-6.04,-3,;-4.7,-3.77,;-3.37,-3,)|	InChI=1S/C27H30N6O3/c1-35-20-13-11-19(12-14-20)33-26-23(25(28)30-16-31-26)24(32-33)18-9-7-17(8-10-18)15-29-27(34)21-5-3-4-6-22(21)36-2/h3-10,16,19-20H,11-15H2,1-2H3,(H,29,34)(H2,28,30,31)	VKHLIGZYZGNAAT-UHFFFAOYSA-N	412826	US10399989, Example 39::N-[[4-[4-amino-1-(4-methoxycyclohexyl)pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]methyl]-2-methoxy-benzamid::US10611766, Example 39	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412826&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823262	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CC=CC2)c2ncnc(N)c12 |c:25|	InChI=1S/C25H24N6O2/c1-33-20-9-5-4-8-19(20)25(32)27-14-16-10-12-17(13-11-16)22-21-23(26)28-15-29-24(21)31(30-22)18-6-2-3-7-18/h2-5,8-13,15,18H,6-7,14H2,1H3,(H,27,32)(H2,26,28,29)	HUEXSVCOMKLQMM-UHFFFAOYSA-N	412827	US10399989, Example 40::US10611766, Example 40	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412827&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823265	CCOC(=O)C1CCCC(C1)n1nc(-c2ccc(CNC(=O)c3ccccc3OC)cc2)c2c(N)ncnc12	InChI=1S/C29H32N6O4/c1-3-39-29(37)20-7-6-8-21(15-20)35-27-24(26(30)32-17-33-27)25(34-35)19-13-11-18(12-14-19)16-31-28(36)22-9-4-5-10-23(22)38-2/h4-5,9-14,17,20-21H,3,6-8,15-16H2,1-2H3,(H,31,36)(H2,30,32,33)	FPLDSFVCJJWFOY-UHFFFAOYSA-N	412828	US10399989, Example 41::Ethyl 3-[4-amino-3-[4-[[(2-methoxybenzoyl)amino]methyl]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]cyclohexanecarboxylate::US10611766, Example 41	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412828&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823268	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC(C2)C(=O)N(C)C)c2ncnc(N)c12	InChI=1S/C29H33N7O3/c1-35(2)29(38)20-7-6-8-21(15-20)36-27-24(26(30)32-17-33-27)25(34-36)19-13-11-18(12-14-19)16-31-28(37)22-9-4-5-10-23(22)39-3/h4-5,9-14,17,20-21H,6-8,15-16H2,1-3H3,(H,31,37)(H2,30,32,33)	WJWUALCORPPEAK-UHFFFAOYSA-N	412829	US10399989, Example 42::US10611766, Example 42	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412829&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823271	COc1ccc(F)cc1C(=O)NCc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C	InChI=1S/C24H25FN6O2/c1-24(2,3)31-22-19(21(26)28-13-29-22)20(30-31)15-7-5-14(6-8-15)12-27-23(32)17-11-16(25)9-10-18(17)33-4/h5-11,13H,12H2,1-4H3,(H,27,32)(H2,26,28,29)	XPBFJXOQBGFRBP-UHFFFAOYSA-N	412830	US10399989, Example 43::US10611766, Example 43	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412830&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823274	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@H]2C[C@@H](O)C=C2)c2ncnc(N)c12 |r,c:27|	InChI=1S/C25H24N6O3/c1-34-20-5-3-2-4-19(20)25(33)27-13-15-6-8-16(9-7-15)22-21-23(26)28-14-29-24(21)31(30-22)17-10-11-18(32)12-17/h2-11,14,17-18,32H,12-13H2,1H3,(H,27,33)(H2,26,28,29)	MPYBIRVGTIQZJU-UHFFFAOYSA-N	412831	US10399989, Example 44::US10611766, Example 44	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412831&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823277	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@@H](O)C3CC23)c2ncnc(N)c12 |r|	InChI=1S/C26H26N6O3/c1-35-21-5-3-2-4-16(21)26(34)28-12-14-6-8-15(9-7-14)23-22-24(27)29-13-30-25(22)32(31-23)19-11-20(33)18-10-17(18)19/h2-9,13,17-20,33H,10-12H2,1H3,(H,28,34)(H2,27,29,30)	GCCWPAARIVMAAH-UHFFFAOYSA-N	412832	US10399989, Example 45::US10611766, Example 45	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412832&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823280	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(CC2)OC(=O)c2ccc(C)cc2)c2ncnc(N)c12 |(3.02,11.97,;2.37,10.57,;3.46,9.48,;4.95,9.88,;6.04,8.79,;5.64,7.3,;4.15,6.9,;3.06,7.99,;1.57,7.59,;.49,8.68,;1.18,6.11,;-.31,5.71,;-.71,4.22,;.38,3.13,;-.02,1.64,;-1.51,1.25,;-2.6,2.33,;-2.2,3.82,;-1.91,-.24,;-1,-1.49,;-1.91,-2.73,;-1.51,-4.22,;-2.6,-5.31,;-2.2,-6.8,;-.71,-7.2,;.38,-6.11,;-.02,-4.62,;-.31,-8.68,;1.18,-9.08,;1.57,-10.57,;2.27,-7.99,;3.75,-8.39,;4.84,-7.3,;4.48,-5.78,;5.57,-4.69,;2.96,-5.42,;1.87,-6.51,;-3.37,-2.26,;-4.7,-3.03,;-6.04,-2.26,;-6.04,-.72,;-4.7,.05,;-4.7,1.59,;-3.37,-.72,)|	InChI=1S/C34H34N6O4/c1-21-7-11-24(12-8-21)34(42)44-26-17-15-25(16-18-26)40-32-29(31(35)37-20-38-32)30(39-40)23-13-9-22(10-14-23)19-36-33(41)27-5-3-4-6-28(27)43-2/h3-14,20,25-26H,15-19H2,1-2H3,(H,36,41)(H2,35,37,38)	PWBUMNCPVWMJLO-UHFFFAOYSA-N	412833	US10399989, Example 46::US10611766, Example 46	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412833&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823283	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@H](O)C=C2)c2ncnc(N)c12 |r,c:27|	InChI=1S/C25H24N6O3/c1-34-20-5-3-2-4-19(20)25(33)27-13-15-6-8-16(9-7-15)22-21-23(26)28-14-29-24(21)31(30-22)17-10-11-18(32)12-17/h2-11,14,17-18,32H,12-13H2,1H3,(H,27,33)(H2,26,28,29)	MPYBIRVGTIQZJU-UHFFFAOYSA-N	412834	US10399989, Example 47::US10611766, Example 47	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412834&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823286	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@H](OC(=O)C(C)(C)C)C=C2)c2ncnc(N)c12 |r,c:33|	InChI=1S/C30H32N6O4/c1-30(2,3)29(38)40-21-14-13-20(15-21)36-27-24(26(31)33-17-34-27)25(35-36)19-11-9-18(10-12-19)16-32-28(37)22-7-5-6-8-23(22)39-4/h5-14,17,20-21H,15-16H2,1-4H3,(H,32,37)(H2,31,33,34)	XVVQHHNAKHSVCB-UHFFFAOYSA-N	412835	US10399989, Example 48::US10611766, Example 48	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412835&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823289	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC=C2)c2ncnc(N)c12 |c:27|	InChI=1S/C26H26N6O2/c1-34-21-10-6-5-9-20(21)26(33)28-15-17-11-13-18(14-12-17)23-22-24(27)29-16-30-25(22)32(31-23)19-7-3-2-4-8-19/h3,5-7,9-14,16,19H,2,4,8,15H2,1H3,(H,28,33)(H2,27,29,30)	BHIIMLQUQYIITN-UHFFFAOYSA-N	412836	US10399989, Example 49::N-[[4-(4-amino-1-cyclohex-2-en-1-yl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 49	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412836&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823292	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@H]2C[C@H](O)C=C2)c2ncnc(N)c12 |r,c:27|	InChI=1S/C25H24N6O3/c1-34-20-5-3-2-4-19(20)25(33)27-13-15-6-8-16(9-7-15)22-21-23(26)28-14-29-24(21)31(30-22)17-10-11-18(32)12-17/h2-11,14,17-18,32H,12-13H2,1H3,(H,27,33)(H2,26,28,29)	MPYBIRVGTIQZJU-UHFFFAOYSA-N	412837	US10399989, Example 50::US10611766, Example 50	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412837&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823295	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C	InChI=1S/C24H26N6O2/c1-24(2,3)30-22-19(21(25)27-14-28-22)20(29-30)16-11-9-15(10-12-16)13-26-23(31)17-7-5-6-8-18(17)32-4/h5-12,14H,13H2,1-4H3,(H,26,31)(H2,25,27,28)	ZTQVREOZSGAIKH-UHFFFAOYSA-N	412838	US10399989, Example 51::N-[[4-(4-amino-1-tert-butyl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 51	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412838&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823298	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CC3CC3C2)c2ncnc(N)c12	InChI=1S/C26H26N6O2/c1-34-21-5-3-2-4-20(21)26(33)28-13-15-6-8-16(9-7-15)23-22-24(27)29-14-30-25(22)32(31-23)19-11-17-10-18(17)12-19/h2-9,14,17-19H,10-13H2,1H3,(H,28,33)(H2,27,29,30)	DGQAUJVXLDIUGP-UHFFFAOYSA-N	412839	US10399989, Example 52::US10611766, Example 52	Epidermal growth factor receptor	Homo sapiens		 55							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412839&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823301	COc1ccc(F)cc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@@H](O)C=C2)c2ncnc(N)c12 |r,c:28|	InChI=1S/C25H23FN6O3/c1-35-20-9-6-16(26)10-19(20)25(34)28-12-14-2-4-15(5-3-14)22-21-23(27)29-13-30-24(21)32(31-22)17-7-8-18(33)11-17/h2-10,13,17-18,33H,11-12H2,1H3,(H,28,34)(H2,27,29,30)	HNRHMRWVXPQSJZ-UHFFFAOYSA-N	412840	US10399989, Example 53::US10611766, Example 53	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412840&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823304	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@@H](F)C=C2)c2ncnc(N)c12 |r,c:27|	InChI=1S/C25H23FN6O2/c1-34-20-5-3-2-4-19(20)25(33)28-13-15-6-8-16(9-7-15)22-21-23(27)29-14-30-24(21)32(31-22)18-11-10-17(26)12-18/h2-11,14,17-18H,12-13H2,1H3,(H,28,33)(H2,27,29,30)	FQZHOFGGGRJGJS-UHFFFAOYSA-N	412841	US10399989, Example 54::N-[[4-[4-amino-1-[(1R,4R)-4-fluorocyclopent-2-en-1-yl]pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 54	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412841&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823307	CCO[C@@H]1C[C@H](C=C1)n1nc(-c2ccc(CNC(=O)c3ccccc3OC)cc2)c2c(N)ncnc12 |r,c:6|	InChI=1S/C27H28N6O3/c1-3-36-20-13-12-19(14-20)33-26-23(25(28)30-16-31-26)24(32-33)18-10-8-17(9-11-18)15-29-27(34)21-6-4-5-7-22(21)35-2/h4-13,16,19-20H,3,14-15H2,1-2H3,(H,29,34)(H2,28,30,31)	NUJHFBUUXCSHKT-UHFFFAOYSA-N	412842	US10399989, Example 55::US10611766, Example 55	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412842&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823310	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2CCc3ccccc23)c2ncnc(N)c12 |r|	InChI=1S/C29H26N6O2/c1-37-24-9-5-4-8-22(24)29(36)31-16-18-10-12-20(13-11-18)26-25-27(30)32-17-33-28(25)35(34-26)23-15-14-19-6-2-3-7-21(19)23/h2-13,17,23H,14-16H2,1H3,(H,31,36)(H2,30,32,33)	WUPKILXEXIRKKI-UHFFFAOYSA-N	412843	US10399989, Example 56::N-[[4-[4-amino-1-[(1R)-indan-1-yl]pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 56	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412843&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823313	COCCO[C@@H]1C[C@H](C=C1)n1nc(-c2ccc(CNC(=O)c3ccccc3OC)cc2)c2c(N)ncnc12 |r,c:8|	InChI=1S/C28H30N6O4/c1-36-13-14-38-21-12-11-20(15-21)34-27-24(26(29)31-17-32-27)25(33-34)19-9-7-18(8-10-19)16-30-28(35)22-5-3-4-6-23(22)37-2/h3-12,17,20-21H,13-16H2,1-2H3,(H,30,35)(H2,29,31,32)	DLLULRWIUFGWJO-UHFFFAOYSA-N	412844	US10399989, Example 57::US10611766, Example 57	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412844	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412844&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823316	COCCNc1ncnc2n(nc(-c3ccc(CNC(=O)c4ccccc4OC)cc3)c12)[C@@H]1C[C@@H](O)C=C1 |r,c:40|	InChI=1S/C28H30N6O4/c1-37-14-13-29-26-24-25(33-34(27(24)32-17-31-26)20-11-12-21(35)15-20)19-9-7-18(8-10-19)16-30-28(36)22-5-3-4-6-23(22)38-2/h3-12,17,20-21,35H,13-16H2,1-2H3,(H,30,36)(H,29,31,32)	XGCGFKBEPOMUBF-UHFFFAOYSA-N	412845	US10399989, Example 58::US10611766, Example 58	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412845&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823319	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@@H](N)C=C2)c2ncnc(N)c12 |r,c:27|	InChI=1S/C25H25N7O2/c1-34-20-5-3-2-4-19(20)25(33)28-13-15-6-8-16(9-7-15)22-21-23(27)29-14-30-24(21)32(31-22)18-11-10-17(26)12-18/h2-11,14,17-18H,12-13,26H2,1H3,(H,28,33)(H2,27,29,30)	RZXCIRZQHJRUTI-UHFFFAOYSA-N	412846	US10399989, Example 59::US10611766, Example 59	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412846	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412846&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823322	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@@H](NC(C)=O)C=C2)c2ncnc(N)c12 |r,c:30|	InChI=1S/C27H27N7O3/c1-16(35)32-19-11-12-20(13-19)34-26-23(25(28)30-15-31-26)24(33-34)18-9-7-17(8-10-18)14-29-27(36)21-5-3-4-6-22(21)37-2/h3-12,15,19-20H,13-14H2,1-2H3,(H,29,36)(H,32,35)(H2,28,30,31)	ZBLFVHJQMNFDSU-UHFFFAOYSA-N	412847	US10399989, Example 60::US10611766, Example 60	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412847	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412847&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823325	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn([C@@H]2C[C@H](C=C2)n2ccnn2)c2ncnc(N)c12 |r,c:26|	InChI=1S/C27H25N9O2/c1-38-22-5-3-2-4-21(22)27(37)29-15-17-6-8-18(9-7-17)24-23-25(28)30-16-31-26(23)36(33-24)20-11-10-19(14-20)35-13-12-32-34-35/h2-13,16,19-20H,14-15H2,1H3,(H,29,37)(H2,28,30,31)	BAWGWCRHRFHTAJ-UHFFFAOYSA-N	412848	US10399989, Example 61::US10611766, Example 61	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412848&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823328	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(C)C2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-16-7-12-19(13-16)32-25-22(24(27)29-15-30-25)23(31-32)18-10-8-17(9-11-18)14-28-26(33)20-5-3-4-6-21(20)34-2/h3-6,8-11,15-16,19H,7,12-14H2,1-2H3,(H,28,33)(H2,27,29,30)	PDTLEIMQPNWRHG-UHFFFAOYSA-N	412849	US10399989, Example 62::US10611766, Example 62	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412849&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823331	COc1ccc(F)cc1C(=O)NCc1ccc(cc1F)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H24F2N6O2/c1-35-20-9-8-16(26)11-18(20)25(34)29-12-15-7-6-14(10-19(15)27)22-21-23(28)30-13-31-24(21)33(32-22)17-4-2-3-5-17/h6-11,13,17H,2-5,12H2,1H3,(H,29,34)(H2,28,30,31)	UDNOQNTTWADXJW-UHFFFAOYSA-N	412850	US10399989, Example 63::US10611766, Example 63	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412850&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823334	COc1ccccc1C(=O)NC(C)c1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-16(30-26(33)20-9-5-6-10-21(20)34-2)17-11-13-18(14-12-17)23-22-24(27)28-15-29-25(22)32(31-23)19-7-3-4-8-19/h5-6,9-16,19H,3-4,7-8H2,1-2H3,(H,30,33)(H2,27,28,29)	FELSNVMDFOTJDB-UHFFFAOYSA-N	412851	US10399989, Example 64::US10611766, Example 64	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412851&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823337	COc1ccc(C)cc1C(=O)NCc1ccc(cc1F)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H27FN6O2/c1-15-7-10-21(35-2)19(11-15)26(34)29-13-17-9-8-16(12-20(17)27)23-22-24(28)30-14-31-25(22)33(32-23)18-5-3-4-6-18/h7-12,14,18H,3-6,13H2,1-2H3,(H,29,34)(H2,28,30,31)	JYMRQJAVJMWPIC-UHFFFAOYSA-N	412852	US10399989, Example 65::US10611766, Example 65	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412852&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823340	COc1ccccc1C(=O)NCc1ccc(cc1F)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H25FN6O2/c1-34-20-9-5-4-8-18(20)25(33)28-13-16-11-10-15(12-19(16)26)22-21-23(27)29-14-30-24(21)32(31-22)17-6-2-3-7-17/h4-5,8-12,14,17H,2-3,6-7,13H2,1H3,(H,28,33)(H2,27,29,30)	IYWIXTKITRLKTP-UHFFFAOYSA-N	412853	US10399989, Example 66::N-[[4-(4-amino-1-cyclopentyl-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluoro-phenyl]methyl]-2-methoxy-benzamide::US10611766, Example 66	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412853&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823343	COc1ccccc1C(=O)NC1(CC1)c1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C27H28N6O2/c1-35-21-9-5-4-8-20(21)26(34)31-27(14-15-27)18-12-10-17(11-13-18)23-22-24(28)29-16-30-25(22)33(32-23)19-6-2-3-7-19/h4-5,8-13,16,19H,2-3,6-7,14-15H2,1H3,(H,31,34)(H2,28,29,30)	UCSIVZACDDZHET-UHFFFAOYSA-N	412854	US10399989, Example 67::US10611766, Example 67	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412854	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412854&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823346	COc1cccc2ccnc(C(=O)NCc3ccc(cc3)-c3nn(C4CCCC4)c4ncnc(N)c34)c12	InChI=1S/C28H27N7O2/c1-37-21-8-4-5-18-13-14-30-25(22(18)21)28(36)31-15-17-9-11-19(12-10-17)24-23-26(29)32-16-33-27(23)35(34-24)20-6-2-3-7-20/h4-5,8-14,16,20H,2-3,6-7,15H2,1H3,(H,31,36)(H2,29,32,33)	AMXPAPGKEVANSU-UHFFFAOYSA-N	412855	US10399989, Example 68	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412855	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412855&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823349	Nc1ncnc2n(nc(-c3ccc(CNC(=O)c4nccc5ccccc45)cc3)c12)C1CCCC1	InChI=1S/C27H25N7O/c28-25-22-23(33-34(20-6-2-3-7-20)26(22)32-16-31-25)19-11-9-17(10-12-19)15-30-27(35)24-21-8-4-1-5-18(21)13-14-29-24/h1,4-5,8-14,16,20H,2-3,6-7,15H2,(H,30,35)(H2,28,31,32)	GGUZZIYJAKQCPH-UHFFFAOYSA-N	412856	US10399989, Example 69::US10611766, Example 69	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412856	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412856&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823352	Nc1ncnc2n(nc(-c3ccc(CNC(=O)c4cccc5cccnc45)cc3)c12)C1CCCC1	InChI=1S/C27H25N7O/c28-25-22-24(33-34(20-7-1-2-8-20)26(22)32-16-31-25)19-12-10-17(11-13-19)15-30-27(35)21-9-3-5-18-6-4-14-29-23(18)21/h3-6,9-14,16,20H,1-2,7-8,15H2,(H,30,35)(H2,28,31,32)	YOLCJXBLALVLLH-UHFFFAOYSA-N	412857	US10399989, Example 70::US10611766, Example 70	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412857	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412857&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823358	COc1ccccc1C(=O)NCc1c(F)cc(cc1F)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C25H24F2N6O2/c1-35-20-9-5-4-8-16(20)25(34)29-12-17-18(26)10-14(11-19(17)27)22-21-23(28)30-13-31-24(21)33(32-22)15-6-2-3-7-15/h4-5,8-11,13,15H,2-3,6-7,12H2,1H3,(H,29,34)(H2,28,30,31)	AMQBJODOYRDTEZ-UHFFFAOYSA-N	412860	US10399989, Example 73::US10611766, Example 73	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412860	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412860&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823361	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(CC(C)O)c2ncnc(N)c12	InChI=1S/C23H24N6O3/c1-14(30)12-29-22-19(21(24)26-13-27-22)20(28-29)16-9-7-15(8-10-16)11-25-23(31)17-5-3-4-6-18(17)32-2/h3-10,13-14,30H,11-12H2,1-2H3,(H,25,31)(H2,24,26,27)	XEMAVKONWQSXRA-UHFFFAOYSA-N	412861	US10399989, Example 74::US10611766, Example 74	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412861	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412861&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823364	COc1cc(ccc1CNC(=O)c1ccccc1OC)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O3/c1-34-20-10-6-5-9-19(20)26(33)28-14-17-12-11-16(13-21(17)35-2)23-22-24(27)29-15-30-25(22)32(31-23)18-7-3-4-8-18/h5-6,9-13,15,18H,3-4,7-8,14H2,1-2H3,(H,28,33)(H2,27,29,30)	LRSSOGFVVJGTNO-UHFFFAOYSA-N	412862	US10399989, Example 75::US10611766, Example 75	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412862	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412862&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823367	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C(C)C)c2ncnc(N)c12	InChI=1S/C23H24N6O2/c1-14(2)29-22-19(21(24)26-13-27-22)20(28-29)16-10-8-15(9-11-16)12-25-23(30)17-6-4-5-7-18(17)31-3/h4-11,13-14H,12H2,1-3H3,(H,25,30)(H2,24,26,27)	UVWGOEJXHFKBSC-UHFFFAOYSA-N	412863	US10399989, Example 78::US10399989, Example 76::US10611766, Example 78	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412863	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412863&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823370	COc1ccccc1C(=O)NCc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)c(OC)c1	InChI=1S/C26H28N6O3/c1-34-20-10-6-5-9-19(20)26(33)28-14-16-11-12-18(21(13-16)35-2)23-22-24(27)29-15-30-25(22)32(31-23)17-7-3-4-8-17/h5-6,9-13,15,17H,3-4,7-8,14H2,1-2H3,(H,28,33)(H2,27,29,30)	GJBQEPHXKFYVGX-UHFFFAOYSA-N	412864	US10399989, Example 77::US10611766, Example 77	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412864	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412864&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823373	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C(C)C)c2ncnc(N)c12	InChI=1S/C23H24N6O2/c1-14(2)29-22-19(21(24)26-13-27-22)20(28-29)16-10-8-15(9-11-16)12-25-23(30)17-6-4-5-7-18(17)31-3/h4-11,13-14H,12H2,1-3H3,(H,25,30)(H2,24,26,27)	UVWGOEJXHFKBSC-UHFFFAOYSA-N	412863	US10399989, Example 78::US10399989, Example 76::US10611766, Example 78	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412863	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412863&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823376	COc1ccccc1C(=O)NCc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)c(C)c1	InChI=1S/C26H28N6O2/c1-16-13-17(14-28-26(33)20-9-5-6-10-21(20)34-2)11-12-19(16)23-22-24(27)29-15-30-25(22)32(31-23)18-7-3-4-8-18/h5-6,9-13,15,18H,3-4,7-8,14H2,1-2H3,(H,28,33)(H2,27,29,30)	UYLYEFFJOOWKHR-UHFFFAOYSA-N	412866	US10399989, Example 79::US10611766, Example 79	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412866	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412866&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823379	CC(C)c1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C27H30N6O/c1-17(2)21-9-5-6-10-22(21)27(34)29-15-18-11-13-19(14-12-18)24-23-25(28)30-16-31-26(23)33(32-24)20-7-3-4-8-20/h5-6,9-14,16-17,20H,3-4,7-8,15H2,1-2H3,(H,29,34)(H2,28,30,31)	QGNJCRSTJRKSSW-UHFFFAOYSA-N	412867	US10399989, Example 80::US10611766, Example 80	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412867&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823383	Nc1ncnc2n(nc(-c3ccc(CNC(=O)c4nc5ccccc5s4)cc3)c12)C1CCCC1	InChI=1S/C25H23N7OS/c26-22-20-21(31-32(17-5-1-2-6-17)23(20)29-14-28-22)16-11-9-15(10-12-16)13-27-24(33)25-30-18-7-3-4-8-19(18)34-25/h3-4,7-12,14,17H,1-2,5-6,13H2,(H,27,33)(H2,26,28,29)	URYCAHBACSLGIY-UHFFFAOYSA-N	412869	US10399989, Example 82::US10611766, Example 82	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412869&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823392	Nc1ncnc2n(nc(-c3ccc(CNC(=O)c4cc5ccccc5[nH]4)cc3)c12)C1CCCC1	InChI=1S/C26H25N7O/c27-24-22-23(32-33(19-6-2-3-7-19)25(22)30-15-29-24)17-11-9-16(10-12-17)14-28-26(34)21-13-18-5-1-4-8-20(18)31-21/h1,4-5,8-13,15,19,31H,2-3,6-7,14H2,(H,28,34)(H2,27,29,30)	ABAPXGKEVNECFX-UHFFFAOYSA-N	412875	US10399989, Example 88::US10611766, Example 88	Epidermal growth factor receptor	Homo sapiens		 5500							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412875&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823395	COc1ccccc1C(=O)NCc1ccc(cc1C)-c1nn(C2CCCC2)c2ncnc(N)c12	InChI=1S/C26H28N6O2/c1-16-13-17(11-12-18(16)14-28-26(33)20-9-5-6-10-21(20)34-2)23-22-24(27)29-15-30-25(22)32(31-23)19-7-3-4-8-19/h5-6,9-13,15,19H,3-4,7-8,14H2,1-2H3,(H,28,33)(H2,27,29,30)	NLLWQJFENQIOAH-UHFFFAOYSA-N	412876	US10399989, Example 89::US10611766, Example 89	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412876&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823398	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(CC(F)(F)F)c2ncnc(N)c12	InChI=1S/C22H19F3N6O2/c1-33-16-5-3-2-4-15(16)21(32)27-10-13-6-8-14(9-7-13)18-17-19(26)28-12-29-20(17)31(30-18)11-22(23,24)25/h2-9,12H,10-11H2,1H3,(H,27,32)(H2,26,28,29)	ATZQNAISFIATKJ-UHFFFAOYSA-N	412877	US10399989, Example 90::US10611766, Example 90	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412877&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823401	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(C)(O)CC2)c2ncnc(N)c12 |w:20.22|	InChI=1S/C27H30N6O3/c1-27(35)13-11-19(12-14-27)33-25-22(24(28)30-16-31-25)23(32-33)18-9-7-17(8-10-18)15-29-26(34)20-5-3-4-6-21(20)36-2/h3-10,16,19,35H,11-15H2,1-2H3,(H,29,34)(H2,28,30,31)	XTFLKGHHTCJHHC-UHFFFAOYSA-N	412878	US10399989, Example 91::US10611766, Example 92	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412878	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412878&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823404	COc1ccccc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(C)(O)CC2)c2ncnc(N)c12 |w:20.22|	InChI=1S/C27H30N6O3/c1-27(35)13-11-19(12-14-27)33-25-22(24(28)30-16-31-25)23(32-33)18-9-7-17(8-10-18)15-29-26(34)20-5-3-4-6-21(20)36-2/h3-10,16,19,35H,11-15H2,1-2H3,(H,29,34)(H2,28,30,31)	XTFLKGHHTCJHHC-UHFFFAOYSA-N	412879	US10399989, Example 92	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412879	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412879&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823407	COc1ccc(F)cc1C(=O)NCc1ccc(cc1)-c1nn(CC(F)(F)F)c2ncnc(N)c12	InChI=1S/C22H18F4N6O2/c1-34-16-7-6-14(23)8-15(16)21(33)28-9-12-2-4-13(5-3-12)18-17-19(27)29-11-30-20(17)32(31-18)10-22(24,25)26/h2-8,11H,9-10H2,1H3,(H,28,33)(H2,27,29,30)	JNAXEPQUOQFSJZ-UHFFFAOYSA-N	412880	US10399989, Example 93::US10611766, Example 93	Epidermal growth factor receptor	Homo sapiens		>10000							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412880	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412880&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823410	COc1ccc(F)cc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(C)(O)CC2)c2ncnc(N)c12 |w:21.23|	InChI=1S/C27H29FN6O3/c1-27(36)11-9-19(10-12-27)34-25-22(24(29)31-15-32-25)23(33-34)17-5-3-16(4-6-17)14-30-26(35)20-13-18(28)7-8-21(20)37-2/h3-8,13,15,19,36H,9-12,14H2,1-2H3,(H,30,35)(H2,29,31,32)	WXZULZJUORXVHF-UHFFFAOYSA-N	412881	US10399989, Example 94::US10611766, Example 95	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412881	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412881&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
823413	COc1ccc(F)cc1C(=O)NCc1ccc(cc1)-c1nn(C2CCC(C)(O)CC2)c2ncnc(N)c12 |w:21.23|	InChI=1S/C27H29FN6O3/c1-27(36)11-9-19(10-12-27)34-25-22(24(29)31-15-32-25)23(33-34)17-5-3-16(4-6-17)14-30-26(35)20-13-18(28)7-8-21(20)37-2/h3-8,13,15,19,36H,9-12,14H2,1-2H3,(H,30,35)(H2,29,31,32)	WXZULZJUORXVHF-UHFFFAOYSA-N	412882	US10399989, Example 95	Epidermal growth factor receptor	Homo sapiens		 550							US Patent		10.7270/Q2X92DPS		aid1803805	US10399989	Guisot, N	9/3/2019	7/27/2020	Loxo Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412882	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412882&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827068	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H24F3N5O4/c1-3-22(34)30-16-5-4-6-18(13-16)37-23-19(25(26,27)28)15-29-24(32-23)31-20-8-7-17(14-21(20)35-2)33-9-11-36-12-10-33/h3-8,13-15H,1,9-12H2,2H3,(H,30,34)(H,29,31,32)	NDTRZENFRVHAFZ-UHFFFAOYSA-N	149401	US8975249, I-1::US10434101, Compound I-1::US11096942, Compound I-1	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149401	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149401&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			67513439	252149356							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827070	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H25F3N6O3/c1-3-22(35)30-16-5-4-6-17(13-16)31-23-19(25(26,27)28)15-29-24(33-23)32-20-8-7-18(14-21(20)36-2)34-9-11-37-12-10-34/h3-8,13-15H,1,9-12H2,2H3,(H,30,35)(H2,29,31,32,33)	WXDGNJJCOMJRLQ-UHFFFAOYSA-N	149402	US8975249, I-2::US10434101, Compound I-2::US11096942, Compound I-2	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149402	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149402&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335382	252149357							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827072	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO	InChI=1S/C26H27ClN6O5/c1-3-23(35)29-17-5-4-6-19(13-17)38-25-20(27)15-28-26(31-25)30-21-8-7-18(14-22(21)37-2)32-9-11-33(12-10-32)24(36)16-34/h3-8,13-15,34H,1,9-12,16H2,2H3,(H,29,35)(H,28,30,31)	WIKQZNCZVKHLAP-UHFFFAOYSA-N	149403	US8975249, I-3::US10434101, Compound I-3::US11096942, Compound I-3	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149403	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149403&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335383	252149358							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827074	CC(=O)N1CCN(CC1)c2ccc(c(c2)OC)Nc3ncc(c(n3)Nc4cccc(c4)NC(=O)C=C)C(F)(F)F	InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35)	HUFOZJXAKZVRNJ-UHFFFAOYSA-N	149404	US8975249, I-4::CO-1686::Rociletinib::AVL-301::CNX-419::Tube721::CHEMBL3545308::US10167264, Compound CO-1686::US9783524, CO-1686::US10300058, CO-1686::US10434101, Compound I-4::US11096942, Compound I-4	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149404&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	8JC	5XDK,5XDL	57335384	252149359		CHEMBL3545308					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827076	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H24ClN5O4/c1-3-22(31)27-16-5-4-6-18(13-16)34-23-19(25)15-26-24(29-23)28-20-8-7-17(14-21(20)32-2)30-9-11-33-12-10-30/h3-8,13-15H,1,9-12H2,2H3,(H,27,31)(H,26,28,29)	SGYVANQNHBGWFO-UHFFFAOYSA-N	149405	US8975249, I-15::US8975249, I-5::US10434101, Compound I-5::US11096942, Compound I-5	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149405	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149405&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			49820427	252149360							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827078	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO	InChI=1S/C27H28F3N7O4/c1-3-23(39)32-17-5-4-6-18(13-17)33-25-20(27(28,29)30)15-31-26(35-25)34-21-8-7-19(14-22(21)41-2)36-9-11-37(12-10-36)24(40)16-38/h3-8,13-15,38H,1,9-12,16H2,2H3,(H,32,39)(H2,31,33,34,35)	PCXGVIRJVAHFKJ-UHFFFAOYSA-N	149406	US8975249, I-6::US10434101, Compound I-6::US11096942, Compound I-6	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149406	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149406&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335533	252149361							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827080	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(C)=O	InChI=1S/C28H30F3N7O3/c1-4-25(40)33-19-7-5-8-20(15-19)34-26-22(28(29,30)31)17-32-27(36-26)35-23-10-9-21(16-24(23)41-3)38-12-6-11-37(13-14-38)18(2)39/h4-5,7-10,15-17H,1,6,11-14H2,2-3H3,(H,33,40)(H2,32,34,35,36)	DXLOPZBHQGBEJJ-UHFFFAOYSA-N	149407	US8975249, I-7::US10434101, Compound I-7::US11096942, Compound I-7	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149407	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149407&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335534	252149362							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827082	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H28ClN7O3/c1-4-24(36)29-18-6-5-7-19(14-18)30-25-21(27)16-28-26(32-25)31-22-9-8-20(15-23(22)37-3)34-12-10-33(11-13-34)17(2)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,36)(H2,28,30,31,32)	YNECADZSNDKLQG-UHFFFAOYSA-N	149408	US8975249, I-8::US9796700, Compound I-298::US10434101, Compound I-8::US11096942, Compound I-8	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149408&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335536	252149363							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827084	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H27ClN6O4/c1-4-24(35)29-18-6-5-7-20(14-18)37-25-21(27)16-28-26(31-25)30-22-9-8-19(15-23(22)36-3)33-12-10-32(11-13-33)17(2)34/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,35)(H,28,30,31)	XDXTWQGIOKCMIE-UHFFFAOYSA-N	149409	US8975249, I-9::US10434101, Compound I-9::US11096942, Compound I-9	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149409&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335535	252149364							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827086	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O	InChI=1S/C27H27F3N6O4/c1-4-24(38)32-18-6-5-7-20(14-18)40-25-21(27(28,29)30)16-31-26(34-25)33-22-9-8-19(15-23(22)39-3)36-12-10-35(11-13-36)17(2)37/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,38)(H,31,33,34)	BKGAQRNSVMXWHB-UHFFFAOYSA-N	149410	US8975249, I-10::US10434101, Compound I-10::US11096942, Compound I-10	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149410	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149410&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336240	252149365							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827088	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO	InChI=1S/C27H27F3N6O5/c1-3-23(38)32-17-5-4-6-19(13-17)41-25-20(27(28,29)30)15-31-26(34-25)33-21-8-7-18(14-22(21)40-2)35-9-11-36(12-10-35)24(39)16-37/h3-8,13-15,37H,1,9-12,16H2,2H3,(H,32,38)(H,31,33,34)	WKEXNNJACJTUAS-UHFFFAOYSA-N	149411	US8975249, I-11::US10434101, Compound I-11::US11096942, Compound I-11	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149411	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149411&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335537	252149366							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827090	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO	InChI=1S/C26H28ClN7O4/c1-3-23(36)29-17-5-4-6-18(13-17)30-25-20(27)15-28-26(32-25)31-21-8-7-19(14-22(21)38-2)33-9-11-34(12-10-33)24(37)16-35/h3-8,13-15,35H,1,9-12,16H2,2H3,(H,29,36)(H2,28,30,31,32)	BMMHTJXCXNYDDS-UHFFFAOYSA-N	149412	US8975249, I-12::US10434101, Compound I-12::US11096942, Compound I-12	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149412	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149412&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335674	252149367							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827092	FC(F)Oc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H22F5N5O4/c1-2-21(36)32-15-4-3-5-17(12-15)38-22-18(25(28,29)30)14-31-24(34-22)33-19-7-6-16(13-20(19)39-23(26)27)35-8-10-37-11-9-35/h2-7,12-14,23H,1,8-11H2,(H,32,36)(H,31,33,34)	KUYLULOJVXLEOJ-UHFFFAOYSA-N	149413	US8975249, I-13::US10434101, Compound I-13::US11096942, Compound I-13	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149413	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149413&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335675	252149368							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827094	FC(F)Oc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCOCC1	InChI=1S/C25H23F5N6O3/c1-2-21(37)32-15-4-3-5-16(12-15)33-22-18(25(28,29)30)14-31-24(35-22)34-19-7-6-17(13-20(19)39-23(26)27)36-8-10-38-11-9-36/h2-7,12-14,23H,1,8-11H2,(H,32,37)(H2,31,33,34,35)	AHOJFMYEJUDGPC-UHFFFAOYSA-N	149414	US8975249, I-14::US10434101, Compound I-14::US11096942, Compound I-14	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149414	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149414&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335676	252149369							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827096	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H25ClN6O3/c1-3-22(32)27-16-5-4-6-17(13-16)28-23-19(25)15-26-24(30-23)29-20-8-7-18(14-21(20)33-2)31-9-11-34-12-10-31/h3-8,13-15H,1,9-12H2,2H3,(H,27,32)(H2,26,28,29,30)	WOPHAXPMDNAXKK-UHFFFAOYSA-N	414438	US10434101, Compound I-15::US11096942, Compound I-15	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335677	433914496							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827098	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C26H28F3N7O4S/c1-4-23(37)31-17-6-5-7-18(14-17)32-24-20(26(27,28)29)16-30-25(34-24)33-21-9-8-19(15-22(21)40-2)35-10-12-36(13-11-35)41(3,38)39/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,37)(H2,30,32,33,34)	SHSKZEADGDUNPX-UHFFFAOYSA-N	149416	US8975249, I-17::US10434101, Compound I-17::US11096942, Compound I-17	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149416&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335810	252149370							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827100	CCOc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C30H35ClN6O5/c1-6-26(38)33-20-9-8-10-22(17-20)41-27-23(31)19-32-28(35-27)34-24-12-11-21(18-25(24)40-7-2)36-13-15-37(16-14-36)29(39)42-30(3,4)5/h6,8-12,17-19H,1,7,13-16H2,2-5H3,(H,33,38)(H,32,34,35)	URSWCQCZHBRDPK-UHFFFAOYSA-N	149417	US8975249, I-18::US10434101, Compound I-18::US11096942, Compound I-18	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149417&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335812	252149371							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827102	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)C(F)(F)F	InChI=1S/C28H27F6N7O3/c1-3-23(42)36-17-6-4-7-18(14-17)37-24-20(27(29,30)31)16-35-26(39-24)38-21-9-8-19(15-22(21)44-2)40-10-5-11-41(13-12-40)25(43)28(32,33)34/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,36,42)(H2,35,37,38,39)	XSXWUJOTESYJJR-UHFFFAOYSA-N	149418	US8975249, I-19::US10434101, Compound I-19::US11096942, Compound I-19	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149418&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335811	252149372							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827104	COC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H27F3N6O5/c1-4-23(37)32-17-6-5-7-19(14-17)41-24-20(27(28,29)30)16-31-25(34-24)33-21-9-8-18(15-22(21)39-2)35-10-12-36(13-11-35)26(38)40-3/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,37)(H,31,33,34)	HYWICFNCOAZGSB-UHFFFAOYSA-N	149419	US8975249, I-20::US10434101, Compound I-20::US11096942, Compound I-20	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149419&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336241	252149373							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827106	CNC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H28F3N7O4/c1-4-23(38)33-17-6-5-7-19(14-17)41-24-20(27(28,29)30)16-32-25(35-24)34-21-9-8-18(15-22(21)40-3)36-10-12-37(13-11-36)26(39)31-2/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,39)(H,33,38)(H,32,34,35)	OZBXOHUAVAGHLZ-UHFFFAOYSA-N	149420	US8975249, I-21::US10434101, Compound I-21::US11096942, Compound I-21	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149420	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149420&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335813	252149374							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827108	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C26H27F3N6O5S/c1-4-23(36)31-17-6-5-7-19(14-17)40-24-20(26(27,28)29)16-30-25(33-24)32-21-9-8-18(15-22(21)39-2)34-10-12-35(13-11-34)41(3,37)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,36)(H,30,32,33)	SNFZHTGBYLFGLP-UHFFFAOYSA-N	149421	US8975249, I-22::US10434101, Compound I-22::US11096942, Compound I-22	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149421&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335814	252149375							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827110	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C30H35ClN6O4/c1-6-26(38)33-20-8-7-9-22(16-20)41-28-23(31)19-32-29(35-28)34-24-11-10-21(17-25(24)40-5)36-12-14-37(15-13-36)27(39)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,33,38)(H,32,34,35)	DECLEZRWEXSBKQ-UHFFFAOYSA-N	149422	US8975249, I-23::US10434101, Compound I-23::US11096942, Compound I-23	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149422	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149422&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335951	252149376							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827112	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)C(F)(F)F	InChI=1S/C26H24ClF3N6O4/c1-3-22(37)32-16-5-4-6-18(13-16)40-23-19(27)15-31-25(34-23)33-20-8-7-17(14-21(20)39-2)35-9-11-36(12-10-35)24(38)26(28,29)30/h3-8,13-15H,1,9-12H2,2H3,(H,32,37)(H,31,33,34)	ZISHQPULHRIZOI-UHFFFAOYSA-N	149423	US8975249, I-24::US10434101, Compound I-24::US11096942, Compound I-24	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149423&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335953	252149377							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827114	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C25H27ClN6O5S/c1-4-23(33)28-17-6-5-7-19(14-17)37-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)36-2)31-10-12-32(13-11-31)38(3,34)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,33)(H,27,29,30)	LXSALHKZTCSKQV-UHFFFAOYSA-N	149424	US8975249, I-26::US10434101, Compound I-26::US11096942, Compound I-26	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149424	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149424&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336242	252149378							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827116	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)S(N)(=O)=O	InChI=1S/C25H26F3N7O5S/c1-3-22(36)31-16-5-4-6-18(13-16)40-23-19(25(26,27)28)15-30-24(33-23)32-20-8-7-17(14-21(20)39-2)34-9-11-35(12-10-34)41(29,37)38/h3-8,13-15H,1,9-12H2,2H3,(H,31,36)(H2,29,37,38)(H,30,32,33)	DSKKGMALLDPGIT-UHFFFAOYSA-N	149425	US8975249, I-27::US10434101, Compound I-27::US11096942, Compound I-27	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149425	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149425&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335954	252149379							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827118	CNC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H29F3N8O3/c1-4-23(39)33-17-6-5-7-18(14-17)34-24-20(27(28,29)30)16-32-25(36-24)35-21-9-8-19(15-22(21)41-3)37-10-12-38(13-11-37)26(40)31-2/h4-9,14-16H,1,10-13H2,2-3H3,(H,31,40)(H,33,39)(H2,32,34,35,36)	QBKCKCBRLDNUCY-UHFFFAOYSA-N	149426	US8975249, I-28::US10434101, Compound I-28::US11096942, Compound I-28	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149426&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57335955	252149380							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827120	COC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C27H28F3N7O4/c1-4-23(38)32-17-6-5-7-18(14-17)33-24-20(27(28,29)30)16-31-25(35-24)34-21-9-8-19(15-22(21)40-2)36-10-12-37(13-11-36)26(39)41-3/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,38)(H2,31,33,34,35)	KHVUCJNBJOOTNT-UHFFFAOYSA-N	149427	US8975249, I-29::US10434101, Compound I-29::US11096942, Compound I-29	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149427	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149427&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336096	252149381							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827122	OCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)(F)F)c1	InChI=1S/C27H25F6N7O4/c1-2-22(42)35-16-4-3-5-17(12-16)36-24-19(26(28,29)30)14-34-25(38-24)37-20-7-6-18(13-21(20)44-27(31,32)33)39-8-10-40(11-9-39)23(43)15-41/h2-7,12-14,41H,1,8-11,15H2,(H,35,42)(H2,34,36,37,38)	PPOKBGQNCHKPRL-UHFFFAOYSA-N	149428	US8975249, I-30::US10434101, Compound I-30::US11096942, Compound I-30	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149428&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336097	252149382							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827124	OCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)F)c1	InChI=1S/C27H26F5N7O4/c1-2-22(41)34-16-4-3-5-17(12-16)35-24-19(27(30,31)32)14-33-26(37-24)36-20-7-6-18(13-21(20)43-25(28)29)38-8-10-39(11-9-38)23(42)15-40/h2-7,12-14,25,40H,1,8-11,15H2,(H,34,41)(H2,33,35,36,37)	DYRCSDCGUVHPRS-UHFFFAOYSA-N	149429	US8975249, I-31::US10434101, Compound I-31::US11096942, Compound I-31	Epidermal growth factor receptor	Homo sapiens		<1.000							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149429&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336098	252149383							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827126	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)F)c1	InChI=1S/C27H26F5N7O3/c1-3-23(41)34-17-5-4-6-18(13-17)35-24-20(27(30,31)32)15-33-26(37-24)36-21-8-7-19(14-22(21)42-25(28)29)39-11-9-38(10-12-39)16(2)40/h3-8,13-15,25H,1,9-12H2,2H3,(H,34,41)(H2,33,35,36,37)	NCFGMTUIORXQEA-UHFFFAOYSA-N	149430	US8975249, I-32::US10434101, Compound I-32::US11096942, Compound I-32	Epidermal growth factor receptor	Homo sapiens		<1.000							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149430&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336099	252149384							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827128	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC(F)(F)F)c1	InChI=1S/C27H25F6N7O3/c1-3-23(42)35-17-5-4-6-18(13-17)36-24-20(26(28,29)30)15-34-25(38-24)37-21-8-7-19(14-22(21)43-27(31,32)33)40-11-9-39(10-12-40)16(2)41/h3-8,13-15H,1,9-12H2,2H3,(H,35,42)(H2,34,36,37,38)	XQFBCBIHUAIWGV-UHFFFAOYSA-N	149431	US8975249, I-33::US10434101, Compound I-33::US11096942, Compound I-33	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149431&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336239	252149385							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827130	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)C(C)(C)C	InChI=1S/C30H34F3N7O3/c1-6-25(41)35-19-8-7-9-20(16-19)36-26-22(30(31,32)33)18-34-28(38-26)37-23-11-10-21(17-24(23)43-5)39-12-14-40(15-13-39)27(42)29(2,3)4/h6-11,16-18H,1,12-15H2,2-5H3,(H,35,41)(H2,34,36,37,38)	VSPRQVANTMCJBV-UHFFFAOYSA-N	149432	US8975249, I-34::US10434101, Compound I-34::US11096942, Compound I-34	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149432&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57336243	252149386							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827132	CCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1	InChI=1S/C28H30F3N7O3/c1-4-24(39)33-18-7-6-8-19(15-18)34-26-21(28(29,30)31)17-32-27(36-26)35-22-10-9-20(16-23(22)41-3)37-11-13-38(14-12-37)25(40)5-2/h4,6-10,15-17H,1,5,11-14H2,2-3H3,(H,33,39)(H2,32,34,35,36)	NSHHXIZJTQXLQE-UHFFFAOYSA-N	149433	US8975249, I-35::US10434101, Compound I-35::US11096942, Compound I-35	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334019	252149387							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827134	FC(F)Oc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCOCC1	InChI=1S/C24H22ClF2N5O4/c1-2-21(33)29-15-4-3-5-17(12-15)35-22-18(25)14-28-24(31-22)30-19-7-6-16(13-20(19)36-23(26)27)32-8-10-34-11-9-32/h2-7,12-14,23H,1,8-11H2,(H,29,33)(H,28,30,31)	NXBMDDBXMAQAPS-UHFFFAOYSA-N	149434	US8975249, I-36::US10434101, Compound I-36::US11096942, Compound I-36	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149434&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334020	252149388							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827136	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCCOCC1	InChI=1S/C25H26ClN5O4/c1-3-23(32)28-17-6-4-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)33-2)31-10-5-12-34-13-11-31/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,28,32)(H,27,29,30)	FTEJKODFWXJJEP-UHFFFAOYSA-N	149435	US8975249, I-37::US10434101, Compound I-37::US11096942, Compound I-37	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149435&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334021	252149389							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827138	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCOCC1	InChI=1S/C26H27F3N6O3/c1-3-23(36)31-17-6-4-7-18(14-17)32-24-20(26(27,28)29)16-30-25(34-24)33-21-9-8-19(15-22(21)37-2)35-10-5-12-38-13-11-35/h3-4,6-9,14-16H,1,5,10-13H2,2H3,(H,31,36)(H2,30,32,33,34)	CKHWLGJWGNTAIV-UHFFFAOYSA-N	149436	US8975249, I-38::US10434101, Compound I-38::US11096942, Compound I-38	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149436&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334022	252149390							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827140	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C31H35F3N6O5/c1-6-26(41)36-20-9-7-10-22(17-20)44-27-23(31(32,33)34)19-35-28(38-27)37-24-12-11-21(18-25(24)43-5)39-13-8-14-40(16-15-39)29(42)45-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,36,41)(H,35,37,38)	RVWDJFPNYORBOG-UHFFFAOYSA-N	414460	US10434101, Compound I-39::US11096942, Compound I-39	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414460&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334023	433914518							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827142	COc1cc(ccc1Nc1ncc(Br)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(C)=O	InChI=1S/C26H28BrN7O3/c1-4-24(36)29-18-6-5-7-19(14-18)30-25-21(27)16-28-26(32-25)31-22-9-8-20(15-23(22)37-3)34-12-10-33(11-13-34)17(2)35/h4-9,14-16H,1,10-13H2,2-3H3,(H,29,36)(H2,28,30,31,32)	FXJRSQCZSIOFJL-UHFFFAOYSA-N	149438	US8975249, I-40::US10434101, Compound I-40::US11096942, Compound I-40	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149438&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334179	252149392							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827144	COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)S(C)(=O)=O	InChI=1S/C25H28ClN7O4S/c1-4-23(34)28-17-6-5-7-18(14-17)29-24-20(26)16-27-25(31-24)30-21-9-8-19(15-22(21)37-2)32-10-12-33(13-11-32)38(3,35)36/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,34)(H2,27,29,30,31)	SYBJZAZQBBVLFV-UHFFFAOYSA-N	149439	US8975249, I-41::US10434101, Compound I-41::US11096942, Compound I-41	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149439&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334180	252149393							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827146	COc1cc(ccc1Nc1ncc(c(Oc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C31H35F3N6O4/c1-6-26(41)36-20-8-7-9-22(16-20)44-28-23(31(32,33)34)19-35-29(38-28)37-24-11-10-21(17-25(24)43-5)39-12-14-40(15-13-39)27(42)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,36,41)(H,35,37,38)	PYNFIMQJVVVSBG-UHFFFAOYSA-N	149440	US8975249, I-42::US10434101, Compound I-42::US11096942, Compound I-42	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149440&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			67978922	252149394							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827148	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C30H35ClN6O5/c1-6-26(38)33-20-9-7-10-22(17-20)41-27-23(31)19-32-28(35-27)34-24-12-11-21(18-25(24)40-5)36-13-8-14-37(16-15-36)29(39)42-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,33,38)(H,32,34,35)	FHDQQJPNVWQLDP-UHFFFAOYSA-N	149441	US8975249, I-43::US10434101, Compound I-43::US11096942, Compound I-43	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149441&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334183	252149395							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827150	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C31H36F3N7O4/c1-6-26(42)36-20-9-7-10-21(17-20)37-27-23(31(32,33)34)19-35-28(39-27)38-24-12-11-22(18-25(24)44-5)40-13-8-14-41(16-15-40)29(43)45-30(2,3)4/h6-7,9-12,17-19H,1,8,13-16H2,2-5H3,(H,36,42)(H2,35,37,38,39)	WORKLTLCQSPUJP-UHFFFAOYSA-N	149437	US8975249, I-44::US8975249, I-39::US10434101, Compound I-44::US11096942, Compound I-44	Epidermal growth factor receptor	Homo sapiens		 650							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149437&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334181	252149391							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827152	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(=O)CC(C)(C)C	InChI=1S/C31H36F3N7O3/c1-6-26(42)36-20-8-7-9-21(16-20)37-28-23(31(32,33)34)19-35-29(39-28)38-24-11-10-22(17-25(24)44-5)40-12-14-41(15-13-40)27(43)18-30(2,3)4/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,36,42)(H2,35,37,38,39)	BCSFIPUWAMSZBP-UHFFFAOYSA-N	149443	US8975249, I-45::US10434101, Compound I-45::US11096942, Compound I-45	Epidermal growth factor receptor	Homo sapiens		 65.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149443&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			68027150	252149396							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827154	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C29H33ClN6O5/c1-6-25(37)32-19-8-7-9-21(16-19)40-26-22(30)18-31-27(34-26)33-23-11-10-20(17-24(23)39-5)35-12-14-36(15-13-35)28(38)41-29(2,3)4/h6-11,16-18H,1,12-15H2,2-5H3,(H,32,37)(H,31,33,34)	KJCFRHMSJIYOPR-UHFFFAOYSA-N	149444	US8975249, I-46::US10434101, Compound I-46::US11096942, Compound I-46	Epidermal growth factor receptor	Homo sapiens		 200							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149444&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334328	252149397							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827156	CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC(F)(F)F)c1	InChI=1S/C29H30ClF3N6O5/c1-5-24(40)35-18-7-6-8-20(15-18)42-25-21(30)17-34-26(37-25)36-22-10-9-19(16-23(22)43-29(31,32)33)38-11-13-39(14-12-38)27(41)44-28(2,3)4/h5-10,15-17H,1,11-14H2,2-4H3,(H,35,40)(H,34,36,37)	CQSIBUGHZLHKBV-UHFFFAOYSA-N	149445	US8975249, I-47::US10434101, Compound I-47::US11096942, Compound I-47	Epidermal growth factor receptor	Homo sapiens		>1000							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149445&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334329	252149398							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827158	COC(=O)[C@@H]1CN(CCN1C(C)=O)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1 |r|	InChI=1S/C29H30F3N7O5/c1-5-25(41)34-18-7-6-8-19(13-18)35-26-21(29(30,31)32)15-33-28(37-26)36-22-10-9-20(14-24(22)43-3)38-11-12-39(17(2)40)23(16-38)27(42)44-4/h5-10,13-15,23H,1,11-12,16H2,2-4H3,(H,34,41)(H2,33,35,36,37)	FJEBNLPKFAZSEO-UHFFFAOYSA-N	149446	US8975249, I-48::US10434101, Compound I-48::US11096942, Compound I-48	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149446&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334330	252149399							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827160	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCS(=O)(=O)CC1	InChI=1S/C25H25F3N6O4S/c1-3-22(35)30-16-5-4-6-17(13-16)31-23-19(25(26,27)28)15-29-24(33-23)32-20-8-7-18(14-21(20)38-2)34-9-11-39(36,37)12-10-34/h3-8,13-15H,1,9-12H2,2H3,(H,30,35)(H2,29,31,32,33)	ZUMAVVJXTLHREC-UHFFFAOYSA-N	149447	US8975249, I-49::US10434101, Compound I-49::US11096942, Compound I-49	Epidermal growth factor receptor	Homo sapiens		 5.50							US Patent		10.7270/Q2NK3HD3		aid1803853	US10434101	Lee, K; Niu, D; Petter, RC; Baevsky, MF; Singh, J	10/8/2019	8/16/2020	Celgene Car	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149447&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			57334476	252149400							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827496	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C27H31ClN8O2/c1-7-24(37)31-20-13-21(23(38-6)14-22(20)35(4)11-10-34(2)3)32-27-30-16-19(28)25(33-27)18-12-17-8-9-36(5)26(17)29-15-18/h7-9,12-16H,1,10-11H2,2-6H3,(H,31,37)(H,30,32,33)	KQYKGCIEJNOXHZ-UHFFFAOYSA-N	414520	US10435400, Compound Z-1::N-(5-(5-chloro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrimidin-2-amino)-2-((2-(dimethylamino)ethyl)methylamino)-4-methoxyphenyl)acrylamide ::US10435400, Compound Z-88	Epidermal growth factor receptor	Homo sapiens		 25.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414520&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351738	433914576							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827498	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C29H33ClN8O2/c1-6-26(39)33-22-14-23(25(40-5)15-24(22)38-11-8-20(9-12-38)36(2)3)34-29-32-17-21(30)27(35-29)19-13-18-7-10-37(4)28(18)31-16-19/h6-7,10,13-17,20H,1,8-9,11-12H2,2-5H3,(H,33,39)(H,32,34,35)	UVHIEUQSBNAGDC-UHFFFAOYSA-N	414521	N-(5-(5-chloro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrimidin-2-amino)-2-(4-(dimethylamino)piperidin-1-yl)-4-methoxyphenyl)acrylamide ::US10435400, Compound Z-2	Epidermal growth factor receptor	Homo sapiens		 272							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414521	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414521&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351780	433914577							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827500	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C29H34N8O2/c1-6-27(38)32-23-16-24(26(39-5)17-25(23)37-13-9-21(10-14-37)35(2)3)34-29-30-11-7-22(33-29)20-15-19-8-12-36(4)28(19)31-18-20/h6-8,11-12,15-18,21H,1,9-10,13-14H2,2-5H3,(H,32,38)(H,30,33,34)	ATFSDVWBDUXCBW-UHFFFAOYSA-N	414522	US10435400, Compound Z-4::US10435400, Compound Z-25::N-(2-(4-(dimethylamino)piperidin-1-yl)-4-methoxy-5-(4-(1-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrimidin-2-ylamino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 45.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414522&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351763	433914578							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827502	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C26H29N9O2/c1-5-24(36)30-20-13-21(23(37-4)14-22(20)35-10-8-33(2)9-11-35)32-26-27-7-6-19(31-26)17-12-18-16-29-34(3)25(18)28-15-17/h5-7,12-16H,1,8-11H2,2-4H3,(H,30,36)(H,27,31,32)	CQXQOKDBFDDBCX-UHFFFAOYSA-N	414523	N-(4-methoxy-5-(4-(1-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrimidin-2-ylamino)-2-(4-methylpiperazin-1-yl)phenyl)acrylamide ::US10435400, Compound Z-5	Epidermal growth factor receptor	Homo sapiens		 105							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414523&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351741	433914579							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827504	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C26H31N9O2/c1-7-24(36)30-20-13-21(23(37-6)14-22(20)34(4)11-10-33(2)3)32-26-27-9-8-19(31-26)17-12-18-16-29-35(5)25(18)28-15-17/h7-9,12-16H,1,10-11H2,2-6H3,(H,30,36)(H,27,31,32)	VMAKSZRLTRHLBP-UHFFFAOYSA-N	414524	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrimidin-2-ylamino)phenyl)acrylamide ::US10435400, Compound Z-6	Epidermal growth factor receptor	Homo sapiens		 10.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414524&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351740	433914580							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827506	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C27H32N8O2/c1-7-25(36)30-21-15-22(24(37-6)16-23(21)34(4)13-12-33(2)3)32-27-28-10-8-20(31-27)19-14-18-9-11-35(5)26(18)29-17-19/h7-11,14-17H,1,12-13H2,2-6H3,(H,30,36)(H,28,31,32)	AAGOVSWSOCZTHE-UHFFFAOYSA-N	414525	US10435400, Compound Z-16::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrimidin-2-yl)amino)phenyl)acrylamide ::US10435400, Compound Z-87	Epidermal growth factor receptor	Homo sapiens		 4.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414525&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351782	433914581							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827508	COc1cc(N(C)CCN(C)N)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C26H30FN9O2/c1-6-23(37)31-19-12-20(22(38-5)13-21(19)34(2)9-10-36(4)28)32-26-30-15-18(27)24(33-26)17-11-16-7-8-35(3)25(16)29-14-17/h6-8,11-15H,1,9-10,28H2,2-5H3,(H,31,37)(H,30,32,33)	DXMQBXYUXMLKFF-UHFFFAOYSA-N	414526	US10435400, Compound Z-20	Epidermal growth factor receptor	Homo sapiens		 4.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414526&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584063	433914582							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827510	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(OC)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C28H34N8O3/c1-8-25(37)31-20-14-21(23(38-6)15-22(20)35(4)12-11-34(2)3)32-28-30-17-24(39-7)26(33-28)19-13-18-9-10-36(5)27(18)29-16-19/h8-10,13-17H,1,11-12H2,2-7H3,(H,31,37)(H,30,32,33)	DCRVBQTZXGDDMB-UHFFFAOYSA-N	414528	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((5-methoxy-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrimidin-2-yl)amino)phenyl)acrylamide ::US10435400, Compound Z-21	Epidermal growth factor receptor	Homo sapiens		 9.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414528&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351819	433914584							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827512	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(c(n1)-c1cnc2n(C)ccc2c1)C(F)(F)F	InChI=1S/C28H31F3N8O2/c1-7-24(40)34-20-13-21(23(41-6)14-22(20)38(4)11-10-37(2)3)35-27-33-16-19(28(29,30)31)25(36-27)18-12-17-8-9-39(5)26(17)32-15-18/h7-9,12-16H,1,10-11H2,2-6H3,(H,34,40)(H,33,35,36)	LQCWPTXQHJXMBZ-UHFFFAOYSA-N	414529	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)acrylamide ::US10435400, Compound Z-22	Epidermal growth factor receptor	Homo sapiens		 57.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414529&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351758	433914585							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827514	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C29H34N8O2/c1-6-27(38)32-23-16-24(26(39-5)17-25(23)37-13-9-21(10-14-37)35(2)3)34-29-30-11-7-22(33-29)20-15-19-8-12-36(4)28(19)31-18-20/h6-8,11-12,15-18,21H,1,9-10,13-14H2,2-5H3,(H,32,38)(H,30,33,34)	ATFSDVWBDUXCBW-UHFFFAOYSA-N	414522	US10435400, Compound Z-4::US10435400, Compound Z-25::N-(2-(4-(dimethylamino)piperidin-1-yl)-4-methoxy-5-(4-(1-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrimidin-2-ylamino)phenyl)acrylamide 	Epidermal growth factor receptor	Homo sapiens		 61.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414522&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351763	433914578							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827516	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C27H30N8O2/c1-5-25(36)30-21-15-22(24(37-4)16-23(21)35-12-10-33(2)11-13-35)32-27-28-8-6-20(31-27)19-14-18-7-9-34(3)26(18)29-17-19/h5-9,14-17H,1,10-13H2,2-4H3,(H,30,36)(H,28,31,32)	OWSDOQYLEZXCDX-UHFFFAOYSA-N	414531	US10435400, Compound Z-26	Epidermal growth factor receptor	Homo sapiens		 114							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414531&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351797	433914586							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827518	COc1cc(N2CC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C27H30N8O2/c1-6-25(36)30-21-12-22(24(37-5)13-23(21)35-15-19(16-35)33(2)3)32-27-28-9-7-20(31-27)18-11-17-8-10-34(4)26(17)29-14-18/h6-14,19H,1,15-16H2,2-5H3,(H,30,36)(H,28,31,32)	JJAVGNYXSAFFAY-UHFFFAOYSA-N	414532	US10435400, Compound Z-27	Epidermal growth factor receptor	Homo sapiens		 19.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414532&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351791	433914587							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827520	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C29H33FN8O2/c1-6-26(39)33-22-14-23(25(40-5)15-24(22)38-11-8-20(9-12-38)36(2)3)34-29-32-17-21(30)27(35-29)19-13-18-7-10-37(4)28(18)31-16-19/h6-7,10,13-17,20H,1,8-9,11-12H2,2-5H3,(H,33,39)(H,32,34,35)	ZLFIUNLOACAXDC-UHFFFAOYSA-N	414533	US10435400, Compound Z-29	Epidermal growth factor receptor	Homo sapiens		 118							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414533&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351799	433914588							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827522	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(C)=O)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C29H34N8O3/c1-8-26(39)32-22-14-23(25(40-7)15-24(22)36(5)12-11-35(3)4)33-29-31-17-21(18(2)38)27(34-29)20-13-19-9-10-37(6)28(19)30-16-20/h8-10,13-17H,1,11-12H2,2-7H3,(H,32,39)(H,31,33,34)	BXILVRXAZNCCSR-UHFFFAOYSA-N	414534	US10435400, Compound Z-32	Epidermal growth factor receptor	Homo sapiens		 4.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414534&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584064	433914589							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827524	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C28H32FN9O2/c1-6-25(39)33-21-12-22(24(40-5)13-23(21)38-9-7-19(8-10-38)36(2)3)34-28-31-16-20(29)26(35-28)17-11-18-15-32-37(4)27(18)30-14-17/h6,11-16,19H,1,7-10H2,2-5H3,(H,33,39)(H,31,34,35)	VCLBNNWMEMGQIT-UHFFFAOYSA-N	414535	US10435400, Compound Z-37	Epidermal growth factor receptor	Homo sapiens		 89.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414535	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414535&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351813	433914590							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827526	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(OC)c(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C29H35N9O3/c1-7-26(39)33-21-13-22(24(40-5)14-23(21)38-10-8-20(9-11-38)36(2)3)34-29-31-17-25(41-6)27(35-29)18-12-19-16-32-37(4)28(19)30-15-18/h7,12-17,20H,1,8-11H2,2-6H3,(H,33,39)(H,31,34,35)	FNSYLKDWIHJNRH-UHFFFAOYSA-N	414536	US10435400, Compound Z-38	Epidermal growth factor receptor	Homo sapiens		 35.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414536&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351807	433914591							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827528	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C26H30ClN9O2/c1-7-23(37)31-19-11-20(22(38-6)12-21(19)35(4)9-8-34(2)3)32-26-29-15-18(27)24(33-26)16-10-17-14-30-36(5)25(17)28-13-16/h7,10-15H,1,8-9H2,2-6H3,(H,31,37)(H,29,32,33)	YGCFTZPZGPKBSB-UHFFFAOYSA-N	414537	US10435400, Compound Z-39	Epidermal growth factor receptor	Homo sapiens		 33.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414537	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414537&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351810	433914592							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827530	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C28H32ClN9O2/c1-6-25(39)33-21-12-22(24(40-5)13-23(21)38-9-7-19(8-10-38)36(2)3)34-28-31-16-20(29)26(35-28)17-11-18-15-32-37(4)27(18)30-14-17/h6,11-16,19H,1,7-10H2,2-5H3,(H,33,39)(H,31,34,35)	OTNIUWUFMIZAIX-UHFFFAOYSA-N	414538	US10435400, Compound Z-40	Epidermal growth factor receptor	Homo sapiens		 233							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414538&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351808	433914593							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827532	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C26H30FN9O2/c1-7-23(37)31-19-11-20(22(38-6)12-21(19)35(4)9-8-34(2)3)32-26-29-15-18(27)24(33-26)16-10-17-14-30-36(5)25(17)28-13-16/h7,10-15H,1,8-9H2,2-6H3,(H,31,37)(H,29,32,33)	BUWVUBKOTZMEBD-UHFFFAOYSA-N	414539	US10435400, Compound Z-41	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414539&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351821	433914594							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827534	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(OC)c(n1)-c1cnc2n(C)ncc2c1	InChI=1S/C27H33N9O3/c1-8-24(37)31-19-12-20(22(38-6)13-21(19)35(4)10-9-34(2)3)32-27-29-16-23(39-7)25(33-27)17-11-18-15-30-36(5)26(18)28-14-17/h8,11-16H,1,9-10H2,2-7H3,(H,31,37)(H,29,32,33)	HBGGSKNSBUSMGT-UHFFFAOYSA-N	414540	US10435400, Compound Z-44	Epidermal growth factor receptor	Homo sapiens		 30.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414540&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351817	433914595							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827536	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)cc(Cl)c2c1	InChI=1S/C27H31ClN8O2/c1-7-25(37)31-21-13-22(24(38-6)14-23(21)35(4)11-10-34(2)3)33-27-29-9-8-20(32-27)17-12-18-19(28)16-36(5)26(18)30-15-17/h7-9,12-16H,1,10-11H2,2-6H3,(H,31,37)(H,29,32,33)	IMKPUPMNZVTZOD-UHFFFAOYSA-N	414541	US10435400, Compound Z-54	Epidermal growth factor receptor	Homo sapiens		 2.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414541&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137380724	433914596							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827538	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C27H32N8O2/c1-7-25(36)30-21-15-22(24(37-6)16-23(21)34(4)13-12-33(2)3)32-27-28-10-8-20(31-27)19-14-18-9-11-35(5)26(18)29-17-19/h7-11,14-17H,1,12-13H2,2-6H3,(H,30,36)(H,28,31,32)	AAGOVSWSOCZTHE-UHFFFAOYSA-N	414525	US10435400, Compound Z-16::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrimidin-2-yl)amino)phenyl)acrylamide ::US10435400, Compound Z-87	Epidermal growth factor receptor	Homo sapiens		 8.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414525&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351782	433914581							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827540	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C27H31ClN8O2/c1-7-24(37)31-20-13-21(23(38-6)14-22(20)35(4)11-10-34(2)3)32-27-30-16-19(28)25(33-27)18-12-17-8-9-36(5)26(17)29-15-18/h7-9,12-16H,1,10-11H2,2-6H3,(H,31,37)(H,30,32,33)	KQYKGCIEJNOXHZ-UHFFFAOYSA-N	414520	US10435400, Compound Z-1::N-(5-(5-chloro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrimidin-2-amino)-2-((2-(dimethylamino)ethyl)methylamino)-4-methoxyphenyl)acrylamide ::US10435400, Compound Z-88	Epidermal growth factor receptor	Homo sapiens		 11.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414520&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351738	433914576							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827542	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cccnc1	InChI=1S/C26H31N7O2/c1-5-25(34)29-21-15-22(31-26-28-12-8-20(30-26)18-7-6-11-27-17-18)24(35-4)16-23(21)33-13-9-19(10-14-33)32(2)3/h5-8,11-12,15-17,19H,1,9-10,13-14H2,2-4H3,(H,29,34)(H,28,30,31)	ISTNQWNXBTVXJI-UHFFFAOYSA-N	414544	US10435400, Compound comparative	Epidermal growth factor receptor	Homo sapiens		 3.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414544	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351804	433914597							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827544	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnn(C)c1	InChI=1S/C25H32N8O2/c1-6-24(34)28-20-13-21(30-25-26-10-7-19(29-25)17-15-27-32(4)16-17)23(35-5)14-22(20)33-11-8-18(9-12-33)31(2)3/h6-7,10,13-16,18H,1,8-9,11-12H2,2-5H3,(H,28,34)(H,26,29,30)	NRMSNAPAGMWJJR-UHFFFAOYSA-N	414545	US10435400, Compound Z-17	Epidermal growth factor receptor	Homo sapiens		 218							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414545&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351770	433914598							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827546	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnn(C)c1	InChI=1S/C23H30N8O2/c1-7-22(32)26-18-12-19(21(33-6)13-20(18)30(4)11-10-29(2)3)28-23-24-9-8-17(27-23)16-14-25-31(5)15-16/h7-9,12-15H,1,10-11H2,2-6H3,(H,26,32)(H,24,27,28)	HIGKLOAGMAVMGX-UHFFFAOYSA-N	414546	US10435400, Compound Z-18	Epidermal growth factor receptor	Homo sapiens		 197							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414546&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351720	433914599							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827548	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn(C)c1	InChI=1S/C23H29ClN8O2/c1-7-21(33)27-17-10-18(20(34-6)11-19(17)31(4)9-8-30(2)3)28-23-25-13-16(24)22(29-23)15-12-26-32(5)14-15/h7,10-14H,1,8-9H2,2-6H3,(H,27,33)(H,25,28,29)	PJFGMIMYKFWGLQ-UHFFFAOYSA-N	414547	US10435400, Compound Z-19	Epidermal growth factor receptor	Homo sapiens		 28.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414547	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414547&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351723	433914600							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827550	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn(C)c1	InChI=1S/C25H31ClN8O2/c1-6-23(35)29-19-11-20(22(36-5)12-21(19)34-9-7-17(8-10-34)32(2)3)30-25-27-14-18(26)24(31-25)16-13-28-33(4)15-16/h6,11-15,17H,1,7-10H2,2-5H3,(H,29,35)(H,27,30,31)	KZANZICOFXRRGI-UHFFFAOYSA-N	414548	US10435400, Compound Z-89	Epidermal growth factor receptor	Homo sapiens		 228							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414548	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414548&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			91864591	433914601							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827552	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn(C)c1C	InChI=1S/C24H31ClN8O2/c1-8-22(34)28-18-11-19(21(35-7)12-20(18)32(5)10-9-31(3)4)29-24-26-14-17(25)23(30-24)16-13-27-33(6)15(16)2/h8,11-14H,1,9-10H2,2-7H3,(H,28,34)(H,26,29,30)	OPYKGZUMZATSME-UHFFFAOYSA-N	414549	US10435400, Compound Z-55	Epidermal growth factor receptor	Homo sapiens		 21.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414549	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414549&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351721	433914602							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827554	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnn(C)c1	InChI=1S/C25H31FN8O2/c1-6-23(35)29-19-11-20(22(36-5)12-21(19)34-9-7-17(8-10-34)32(2)3)30-25-27-14-18(26)24(31-25)16-13-28-33(4)15-16/h6,11-15,17H,1,7-10H2,2-5H3,(H,29,35)(H,27,30,31)	NINQZHUKKFUXCY-UHFFFAOYSA-N	414550	US10435400, Compound Z-90	Epidermal growth factor receptor	Homo sapiens		 102							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414550	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414550&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351724	433914603							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827556	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c(C)nn(C)c1C |(-1.61,-15.57,;-.28,-14.8,;1.05,-15.57,;1.05,-17.11,;2.39,-17.88,;2.39,-19.42,;3.72,-20.19,;1.05,-20.19,;1.05,-21.73,;2.39,-22.5,;3.72,-21.73,;2.39,-24.04,;3.72,-17.11,;5.05,-17.88,;6.54,-18.28,;7.63,-17.19,;6.94,-19.77,;8.43,-20.17,;3.72,-15.57,;2.39,-14.8,;2.39,-13.26,;3.72,-12.49,;3.72,-10.95,;5.05,-10.18,;6.39,-10.95,;7.72,-10.18,;6.39,-12.49,;5.05,-13.26,;7.72,-13.26,;9.19,-12.79,;9.96,-11.45,;10.09,-14.03,;9.19,-15.28,;9.96,-16.61,;7.72,-14.8,;6.39,-15.57,)|	InChI=1S/C25H33ClN8O2/c1-9-22(35)28-18-12-19(21(36-8)13-20(18)33(6)11-10-32(4)5)29-25-27-14-17(26)24(30-25)23-15(2)31-34(7)16(23)3/h9,12-14H,1,10-11H2,2-8H3,(H,28,35)(H,27,29,30)	MKBMJBXGOZPFEM-UHFFFAOYSA-N	414551	US10435400, Compound Z-91	Epidermal growth factor receptor	Homo sapiens		 195							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414551&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351735	433914604							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827558	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnn(C)c1	InChI=1S/C23H29FN8O2/c1-7-21(33)27-17-10-18(20(34-6)11-19(17)31(4)9-8-30(2)3)28-23-25-13-16(24)22(29-23)15-12-26-32(5)14-15/h7,10-14H,1,8-9H2,2-6H3,(H,27,33)(H,25,28,29)	AXZHWQXBLMNFGP-UHFFFAOYSA-N	414552	US10435400, Compound Z-93	Epidermal growth factor receptor	Homo sapiens		 42.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414552&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351736	433914605							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827560	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)nc1C	InChI=1S/C24H31ClN8O2/c1-8-22(34)27-18-11-19(21(35-7)12-20(18)32(5)10-9-31(3)4)28-24-26-13-17(25)23(29-24)16-14-33(6)30-15(16)2/h8,11-14H,1,9-10H2,2-7H3,(H,27,34)(H,26,28,29)	CNZDWUJAQGQNHE-UHFFFAOYSA-N	414553	US10435400, Compound Z-94	Epidermal growth factor receptor	Homo sapiens		 20.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414553&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351726	433914606							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827562	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn(C)nc1C	InChI=1S/C26H33ClN8O2/c1-7-24(36)29-20-12-21(23(37-6)13-22(20)35-10-8-17(9-11-35)33(3)4)30-26-28-14-19(27)25(31-26)18-15-34(5)32-16(18)2/h7,12-15,17H,1,8-11H2,2-6H3,(H,29,36)(H,28,30,31)	HBUWJAQEULNYSG-UHFFFAOYSA-N	414555	US10435400, Compound Z-95	Epidermal growth factor receptor	Homo sapiens		 328							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414555	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414555&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351725	433914608							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827564	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn(c1)C1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C34H46ClN9O4/c1-8-30(45)38-26-17-27(29(47-7)18-28(26)42-13-9-23(10-14-42)41(5)6)39-32-36-20-25(35)31(40-32)22-19-37-44(21-22)24-11-15-43(16-12-24)33(46)48-34(2,3)4/h8,17-21,23-24H,1,9-16H2,2-7H3,(H,38,45)(H,36,39,40)	QAOCLLBAMJYFJE-UHFFFAOYSA-N	414556	US10435400, Compound Z-96	Epidermal growth factor receptor	Homo sapiens		 41.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414556	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414556&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351885	433914609							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827566	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn(C)c1C	InChI=1S/C26H33ClN8O2/c1-7-24(36)30-20-12-21(23(37-6)13-22(20)35-10-8-17(9-11-35)33(3)4)31-26-28-15-19(27)25(32-26)18-14-29-34(5)16(18)2/h7,12-15,17H,1,8-11H2,2-6H3,(H,30,36)(H,28,31,32)	AHGBWEPIOHFJFC-UHFFFAOYSA-N	414557	US10435400, Compound Z-97	Epidermal growth factor receptor	Homo sapiens		 341							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414557&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351778	433914610							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827568	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1ccn(C)c1	InChI=1S/C26H32ClN7O2/c1-6-24(35)29-20-13-21(23(36-5)14-22(20)34-11-8-18(9-12-34)32(2)3)30-26-28-15-19(27)25(31-26)17-7-10-33(4)16-17/h6-7,10,13-16,18H,1,8-9,11-12H2,2-5H3,(H,29,35)(H,28,30,31)	QQAOBVYDVCUEEX-UHFFFAOYSA-N	414558	US10435400, Compound Z-98	Epidermal growth factor receptor	Homo sapiens		 407							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414558	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414558&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351779	433914611							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827570	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1ccn(C)c1	InChI=1S/C24H30ClN7O2/c1-7-22(33)27-18-12-19(21(34-6)13-20(18)32(5)11-10-30(2)3)28-24-26-14-17(25)23(29-24)16-8-9-31(4)15-16/h7-9,12-15H,1,10-11H2,2-6H3,(H,27,33)(H,26,28,29)	VIMMWBFDOYNZHI-UHFFFAOYSA-N	414559	US10435400, Compound Z-99	Epidermal growth factor receptor	Homo sapiens		 38.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414559	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414559&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351727	433914612							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827572	COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn(C)c1	InChI=1S/C23H27ClN8O2/c1-5-21(33)27-17-10-18(20(34-4)11-19(17)32-8-6-30(2)7-9-32)28-23-25-13-16(24)22(29-23)15-12-26-31(3)14-15/h5,10-14H,1,6-9H2,2-4H3,(H,27,33)(H,25,28,29)	XQMMZBZROFLQPW-UHFFFAOYSA-N	414560	US10435400, Compound Z-100	Epidermal growth factor receptor	Homo sapiens		 297							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414560	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414560&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351728	433914613							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827574	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn(c1)C(F)F	InChI=1S/C25H29ClF2N8O2/c1-5-22(37)31-18-10-19(21(38-4)11-20(18)35-8-6-16(7-9-35)34(2)3)32-25-29-13-17(26)23(33-25)15-12-30-36(14-15)24(27)28/h5,10-14,16,24H,1,6-9H2,2-4H3,(H,31,37)(H,29,32,33)	MLIQHCLZWYXEAC-UHFFFAOYSA-N	414561	US10435400, Compound Z-101	Epidermal growth factor receptor	Homo sapiens		 112							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414561	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414561&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351802	433914614							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827576	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn[nH]c1	InChI=1S/C24H29ClN8O2/c1-5-22(34)29-18-10-19(30-24-26-14-17(25)23(31-24)15-12-27-28-13-15)21(35-4)11-20(18)33-8-6-16(7-9-33)32(2)3/h5,10-14,16H,1,6-9H2,2-4H3,(H,27,28)(H,29,34)(H,26,30,31)	GCWSZSOEXSYQQN-UHFFFAOYSA-N	414562	US10435400, Compound Z-102	Epidermal growth factor receptor	Homo sapiens		 62.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414562	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414562&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584065	433914615							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827578	CCN(C)CCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cnc3n(C)ccc3c2)cc1NC(=O)C=C	InChI=1S/C28H34N8O2/c1-7-26(37)31-22-16-23(25(38-6)17-24(22)35(4)14-13-34(3)8-2)33-28-29-11-9-21(32-28)20-15-19-10-12-36(5)27(19)30-18-20/h7,9-12,15-18H,1,8,13-14H2,2-6H3,(H,31,37)(H,29,32,33)	ZDCBLUOFFJILLI-UHFFFAOYSA-N	414563	US10435400, Compound Z-105	Epidermal growth factor receptor	Homo sapiens		 7.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414563	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414563&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351856	433914616							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827580	CNCCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cnc3n(C)ccc3c2)cc1NC(=O)C=C	InChI=1S/C26H30N8O2/c1-6-24(35)30-20-14-21(23(36-5)15-22(20)33(3)12-10-27-2)32-26-28-9-7-19(31-26)18-13-17-8-11-34(4)25(17)29-16-18/h6-9,11,13-16,27H,1,10,12H2,2-5H3,(H,30,35)(H,28,31,32)	OECIQEJZCIKFLL-UHFFFAOYSA-N	414564	US10435400, Compound Z-106	Epidermal growth factor receptor	Homo sapiens		 4.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414564	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414564&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584066	433914617							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827582	CCN(CC)CCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cnc3n(C)ccc3c2)cc1NC(=O)C=C	InChI=1S/C29H36N8O2/c1-7-27(38)32-23-17-24(26(39-6)18-25(23)35(4)14-15-37(8-2)9-3)34-29-30-12-10-22(33-29)21-16-20-11-13-36(5)28(20)31-19-21/h7,10-13,16-19H,1,8-9,14-15H2,2-6H3,(H,32,38)(H,30,33,34)	MTVIRVHXMSHNRH-UHFFFAOYSA-N	414565	US10435400, Compound Z-107	Epidermal growth factor receptor	Homo sapiens		 16.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414565	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414565&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351864	433914618							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827584	CCN(C)CCN(C)c1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnc3n(C)ccc3c2)cc1NC(=O)C=C	InChI=1S/C28H33ClN8O2/c1-7-25(38)32-21-14-22(24(39-6)15-23(21)36(4)12-11-35(3)8-2)33-28-31-17-20(29)26(34-28)19-13-18-9-10-37(5)27(18)30-16-19/h7,9-10,13-17H,1,8,11-12H2,2-6H3,(H,32,38)(H,31,33,34)	UTXLNWHESVVNTO-UHFFFAOYSA-N	414566	US10435400, Compound Z-109	Epidermal growth factor receptor	Homo sapiens		 28.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414566&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584067	433914619							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827586	CCN(CC)CCN(C)c1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnc3n(C)ccc3c2)cc1NC(=O)C=C	InChI=1S/C29H35ClN8O2/c1-7-26(39)33-22-15-23(25(40-6)16-24(22)36(4)12-13-38(8-2)9-3)34-29-32-18-21(30)27(35-29)20-14-19-10-11-37(5)28(19)31-17-20/h7,10-11,14-18H,1,8-9,12-13H2,2-6H3,(H,33,39)(H,32,34,35)	MCSYUUQZCNJOLR-UHFFFAOYSA-N	414567	US10435400, Compound Z-110	Epidermal growth factor receptor	Homo sapiens		 40.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414567	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414567&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584068	433914620							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827588	COc1cc(N(C)CCN2CCCC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C29H34N8O2/c1-5-27(38)32-23-17-24(26(39-4)18-25(23)35(2)14-15-37-11-6-7-12-37)34-29-30-10-8-22(33-29)21-16-20-9-13-36(3)28(20)31-19-21/h5,8-10,13,16-19H,1,6-7,11-12,14-15H2,2-4H3,(H,32,38)(H,30,33,34)	INFCCLXLFVBARX-UHFFFAOYSA-N	414568	US10435400, Compound Z-112	Epidermal growth factor receptor	Homo sapiens		 22.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414568	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414568&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351865	433914621							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827590	COc1cc(N2CC(C2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C27H29ClN8O2/c1-6-24(37)31-20-10-21(23(38-5)11-22(20)36-14-18(15-36)34(2)3)32-27-30-13-19(28)25(33-27)17-9-16-7-8-35(4)26(16)29-12-17/h6-13,18H,1,14-15H2,2-5H3,(H,31,37)(H,30,32,33)	WGHQAYSLVVSBMY-UHFFFAOYSA-N	414569	US10435400, Compound Z-113	Epidermal growth factor receptor	Homo sapiens		 121							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414569&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584069	433914622							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827592	COc1cc(N(C)CCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C28H33ClN8O2/c1-7-25(38)32-21-14-22(24(39-6)15-23(21)36(4)11-8-10-35(2)3)33-28-31-17-20(29)26(34-28)19-13-18-9-12-37(5)27(18)30-16-19/h7,9,12-17H,1,8,10-11H2,2-6H3,(H,32,38)(H,31,33,34)	CEMTXHVRPTXOAR-UHFFFAOYSA-N	414570	US10435400, Compound Z-114	Epidermal growth factor receptor	Homo sapiens		 116							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414570&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584070	433914623							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827594	COc1cc(N(C)CCN(C)C(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C29H36N8O2/c1-8-27(38)32-23-16-24(26(39-7)17-25(23)36(5)14-13-35(4)19(2)3)34-29-30-11-9-22(33-29)21-15-20-10-12-37(6)28(20)31-18-21/h8-12,15-19H,1,13-14H2,2-7H3,(H,32,38)(H,30,33,34)	OQZHDVJCVJDGFY-UHFFFAOYSA-N	414571	US10435400, Compound Z-115	Epidermal growth factor receptor	Homo sapiens		 22.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414571	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414571&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351868	433914624							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827596	CNCCN(C)c1cc(OC)c(Nc2ncc(Cl)c(n2)-c2cnc3n(C)ccc3c2)cc1NC(=O)C=C	InChI=1S/C26H29ClN8O2/c1-6-23(36)31-19-12-20(22(37-5)13-21(19)34(3)10-8-28-2)32-26-30-15-18(27)24(33-26)17-11-16-7-9-35(4)25(16)29-14-17/h6-7,9,11-15,28H,1,8,10H2,2-5H3,(H,31,36)(H,30,32,33)	RQYSAGLQHHNYDZ-UHFFFAOYSA-N	414572	US10435400, Compound Z-116	Epidermal growth factor receptor	Homo sapiens		 37.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414572&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351812	433914625							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827598	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C26H29N7O3/c1-6-24(34)29-21-14-20(22(35-5)15-23(21)36-12-11-32(2)3)31-26-27-9-7-19(30-26)18-13-17-8-10-33(4)25(17)28-16-18/h6-10,13-16H,1,11-12H2,2-5H3,(H,29,34)(H,27,30,31)	YGKXJTTWYYHGPP-UHFFFAOYSA-N	414573	US10435400, Compound Z-117	Epidermal growth factor receptor	Homo sapiens		 8.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414573	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414573&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584071	433914626							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827600	COc1cc(OCCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnc2n(C)ccc2c1	InChI=1S/C26H28FN7O3/c1-6-23(35)30-20-12-19(21(36-5)13-22(20)37-10-9-33(2)3)31-26-29-15-18(27)24(32-26)17-11-16-7-8-34(4)25(16)28-14-17/h6-8,11-15H,1,9-10H2,2-5H3,(H,30,35)(H,29,31,32)	DBRMNEBALTXSPS-UHFFFAOYSA-N	414574	US10435400, Compound Z-118	Epidermal growth factor receptor	Homo sapiens		 6.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414574	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414574&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584072	433914627							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827602	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(C)cc(Cl)c2c1	InChI=1S/C27H30Cl2N8O2/c1-7-24(38)32-20-11-21(23(39-6)12-22(20)36(4)9-8-35(2)3)33-27-31-14-18(28)25(34-27)16-10-17-19(29)15-37(5)26(17)30-13-16/h7,10-15H,1,8-9H2,2-6H3,(H,32,38)(H,31,33,34)	MITXBKUWGMHJDT-UHFFFAOYSA-N	414575	US10435400, Compound Z-121	Epidermal growth factor receptor	Homo sapiens		 14.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414575	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414575&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584073	433914628							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827604	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnc2n(C)cc(Cl)c2c1	InChI=1S/C29H32ClFN8O2/c1-6-26(40)34-22-12-23(25(41-5)13-24(22)39-9-7-18(8-10-39)37(2)3)35-29-33-15-21(31)27(36-29)17-11-19-20(30)16-38(4)28(19)32-14-17/h6,11-16,18H,1,7-10H2,2-5H3,(H,34,40)(H,33,35,36)	GPCFAVWDKJYMQR-UHFFFAOYSA-N	414576	US10435400, Compound Z-122	Epidermal growth factor receptor	Homo sapiens		 25.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414576&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584074	433914629							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827606	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(F)c(n1)-c1cnc2n(C)cc(Cl)c2c1	InChI=1S/C27H30ClFN8O2/c1-7-24(38)32-20-11-21(23(39-6)12-22(20)36(4)9-8-35(2)3)33-27-31-14-19(29)25(34-27)16-10-17-18(28)15-37(5)26(17)30-13-16/h7,10-15H,1,8-9H2,2-6H3,(H,32,38)(H,31,33,34)	ZLFCMFZVALRVFO-UHFFFAOYSA-N	414577	US10435400, Compound Z-123	Epidermal growth factor receptor	Homo sapiens		 3.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414577&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584075	433914630							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827608	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cnc2n(ccc2c1)C(C)C	InChI=1S/C29H36N8O2/c1-8-27(38)32-23-16-24(26(39-7)17-25(23)36(6)14-13-35(4)5)34-29-30-11-9-22(33-29)21-15-20-10-12-37(19(2)3)28(20)31-18-21/h8-12,15-19H,1,13-14H2,2-7H3,(H,32,38)(H,30,33,34)	VXZBCEBWZGLYIT-UHFFFAOYSA-N	414578	US10435400, Compound Z-124	Epidermal growth factor receptor	Homo sapiens		 13.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414578&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351866	433914631							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827610	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(ccc2c1)C(C)C	InChI=1S/C29H35ClN8O2/c1-8-26(39)33-22-14-23(25(40-7)15-24(22)37(6)12-11-36(4)5)34-29-32-17-21(30)27(35-29)20-13-19-9-10-38(18(2)3)28(19)31-16-20/h8-10,13-18H,1,11-12H2,2-7H3,(H,33,39)(H,32,34,35)	RHQOODKGFRQIFR-UHFFFAOYSA-N	414579	US10435400, Compound Z-125	Epidermal growth factor receptor	Homo sapiens		 14.0							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414579&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154584076	433914632							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827612	COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnc2n(ccc2c1)C1CC1	InChI=1S/C29H33ClN8O2/c1-6-26(39)33-22-14-23(25(40-5)15-24(22)37(4)12-11-36(2)3)34-29-32-17-21(30)27(35-29)19-13-18-9-10-38(20-7-8-20)28(18)31-16-19/h6,9-10,13-17,20H,1,7-8,11-12H2,2-5H3,(H,33,39)(H,32,34,35)	KMCJVQYGVDKIHH-UHFFFAOYSA-N	414580	US10435400, Compound Z-126	Epidermal growth factor receptor	Homo sapiens		 7.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414580	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414580&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351872	433914633							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827614	CN(C)C/C=C/C(=O)Nc1cc2c(cc1O[C@H]3CCOC3)ncnc2Nc4ccc(c(c4)Cl)F	InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)	ULXXDDBFHOBEHA-UHFFFAOYSA-N	50322823	(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide::CHEMBL1173655::AFATINIB::US9388170, Afatinib::US10085983, Compound BIBW2992::US10196365, Afatinib::US9890168, Compound BIBW2992::US10435400, Compound BIBW2992::WO2022090481, Example afatinib::US11896597, Compound Afatinib::US20240358711, Compound Afatanib	Epidermal growth factor receptor	Homo sapiens		 1.000							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322823&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	0WM	4G5J	10184653	104144352		CHEMBL1173655	DB08916				1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
827616	COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cccnc1	InChI=1S/C26H31N7O2/c1-5-25(34)29-21-15-22(31-26-28-12-8-20(30-26)18-7-6-11-27-17-18)24(35-4)16-23(21)33-13-9-19(10-14-33)32(2)3/h5-8,11-12,15-17,19H,1,9-10,13-14H2,2-4H3,(H,29,34)(H,28,30,31)	ISTNQWNXBTVXJI-UHFFFAOYSA-N	414544	US10435400, Compound comparative	Epidermal growth factor receptor	Homo sapiens		 3.00							US Patent		10.7270/Q20V8G4V		aid1803858	US10435400	Lan, J; Jin, Y; Zhou, F; Xie, J; Shen, S; Hu, Y; Liu, W; Lv, Q	10/8/2019	8/16/2020	Shanghai Haiyan Pharmaceutical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414544	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414544&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			118351804	433914597							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1058678	Fc1ccc(cn1)[C@@H](Nc1cc(Cl)c2ncc(C#N)c(NC3C4CC5CC(C4)CC3C5)c2c1)C1=CN(NN1)C1CC1 |r,wD:7.8,t:39,TLB:20:21:23:26.25.27,THB:25:26:21:23.24.30,25:24:21:26.28.27,28:26:23:21.29.30,28:29:23:26.25.27,20:21:26.28.27:23.24.30,(-3.31,-6.72,;-3.31,-5.18,;-1.98,-4.41,;-1.98,-2.87,;-3.31,-2.1,;-4.65,-2.87,;-4.65,-4.41,;-3.31,-.56,;-1.98,.21,;-.64,-.56,;-.64,-2.1,;.69,-2.87,;.69,-4.41,;2.02,-2.1,;3.36,-2.87,;4.69,-2.1,;4.69,-.56,;6.02,.21,;7.36,.98,;3.36,.21,;3.36,1.75,;4.69,2.52,;5.52,4.42,;5.52,5.96,;6.86,6.72,;8.19,5.96,;8.19,4.42,;6.86,3.65,;7.29,2.49,;6.09,3.16,;6.1,5.56,;2.02,-.56,;.69,.21,;-4.65,.21,;-4.81,1.74,;-6.31,2.06,;-7.08,.72,;-6.05,-.42,;-6.94,3.46,;-6.78,5,;-8.19,4.37,)|	InChI=1S/C31H32ClFN8/c32-25-11-22(37-30(18-1-4-27(33)35-13-18)26-15-41(40-39-26)23-2-3-23)10-24-29(21(12-34)14-36-31(24)25)38-28-19-6-16-5-17(8-19)9-20(28)7-16/h1,4,10-11,13-17,19-20,23,28,30,37,39-40H,2-3,5-9H2,(H,36,38)	WCSFNBUHOWLTAL-UHFFFAOYSA-N	505433	4-(((1S,3S,5S,7S)-adamantan-2- yl)amino)-8-chloro-6-(((S)-(1- cyclopropyl-1H-1,2,3-triazol-4- yl)(6-fluoropyridin-3-yl)methyl- d)amino)quinoline-3-carbonitrile::US11066414, Compound 95	Epidermal growth factor receptor	Homo sapiens		 10.00							US Patent		10.7270/Q2RX9G73		aid1805683	US11066414	Bacon, EM; Balan, G; Chou, C; Clark, CT; Cottell, JJ; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Schroeder, SD; Squires, NH; Stevens, KL; Taylor, JG; Watkins, WJ; Wright, NE; Zipfel, SM	7/20/2021	12/23/2021	Gilead Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=505433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=505433&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			162370495	459090648							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1058727	Fc1ccc(cn1)[C@@H](Nc1cc(Cl)c2ncc(C#N)c(NC3C4CC5CC(C4)CC3C5)c2c1)C1=CN(NN1)C1CC1 |r,wD:7.8,t:39,TLB:30:29:23.24.25:27,THB:20:21:23.24.25:27,25:24:21:26.27.28,25:26:21:23.24.30,30:24:27:21.28.29,(-3.54,-16.59,;-3.9,-15.09,;-5.38,-14.66,;-5.74,-13.17,;-4.63,-12.1,;-3.15,-12.54,;-2.79,-14.03,;-4.99,-10.61,;-3.88,-9.54,;-4.24,-8.05,;-5.72,-7.61,;-6.08,-6.12,;-7.56,-5.68,;-4.97,-5.05,;-5.33,-3.56,;-4.22,-2.49,;-2.74,-2.93,;-1.62,-1.86,;-.51,-.8,;-2.37,-4.42,;-.9,-4.86,;.22,-3.79,;1.59,-3.1,;1.59,-1.7,;2.43,-.23,;3.8,-.92,;3.8,-2.32,;2.96,-3.79,;2.43,-3.02,;1.06,-2.32,;1.06,-.92,;-3.49,-5.49,;-3.13,-6.98,;-6.47,-10.17,;-7.69,-11.11,;-8.96,-10.24,;-8.53,-8.77,;-6.99,-8.72,;-10.41,-10.76,;-11.41,-11.94,;-11.92,-10.49,)|	InChI=1S/C31H32ClFN8/c32-25-11-22(37-30(18-1-4-27(33)35-13-18)26-15-41(40-39-26)23-2-3-23)10-24-29(21(12-34)14-36-31(24)25)38-28-19-6-16-5-17(8-19)9-20(28)7-16/h1,4,10-11,13-17,19-20,23,28,30,37,39-40H,2-3,5-9H2,(H,36,38)	WCSFNBUHOWLTAL-UHFFFAOYSA-N	505486	US11066414, Compound 144::8-chloro-6-(((1-cyclopropyl-1H-1,2,3- triazol-4-yl)(2-methylpyridin-3- yl)methyl-d)amino)-4-(((R)-1- phenylpropyl)amino)quinoline-3- carbonitrile	Epidermal growth factor receptor	Homo sapiens		 2.00							US Patent		10.7270/Q2RX9G73		aid1805683	US11066414	Bacon, EM; Balan, G; Chou, C; Clark, CT; Cottell, JJ; Kim, M; Kirschberg, TA; Link, JO; Phillips, G; Schroeder, SD; Squires, NH; Stevens, KL; Taylor, JG; Watkins, WJ; Wright, NE; Zipfel, SM	7/20/2021	12/23/2021	Gilead Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=505486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=505486&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			162370495	459089589							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1427804	Cc1cc(Nc2ncnn3ccc(CN4[C@H]5CC[C@@H]4C[C@@H](O)C5)c23)ccc1Oc1ccn2ncnc2c1 |r,THB:13:14:22.20.19:16.17|	InChI=1S/C27H28N8O2/c1-17-10-19(2-5-24(17)37-23-7-9-34-25(13-23)28-15-30-34)32-27-26-18(6-8-35(26)31-16-29-27)14-33-20-3-4-21(33)12-22(36)11-20/h2,5-10,13,15-16,20-22,36H,3-4,11-12,14H2,1H3,(H,29,31,32)	IRWZLUDELZLXLL-UHFFFAOYSA-N	684563	US12030897, Example 6	Epidermal growth factor receptor	Homo sapiens		 743							US Patent		10.7270/Q2W66R3G		aid1963935	US12030897	Chen, KX; Jiang, F; Chen, X; Zhang, L; Chen, Z; Yu, Y; Zhou, K; Hu, B; Xie, C; Chen, S	7/9/2024	10/16/2024	Medshine Discovery	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=684563	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=684563&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			157282507	503273940							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1427810	Cc1cc(Nc2ncnn3ccc(CN4[C@H]5CC[C@@H]4C[C@@H](N)C5)c23)ccc1Oc1ccn2ncnc2c1 |r,THB:13:14:22.20.19:16.17|	InChI=1S/C27H29N9O/c1-17-10-20(2-5-24(17)37-23-7-9-35-25(13-23)29-15-31-35)33-27-26-18(6-8-36(26)32-16-30-27)14-34-21-3-4-22(34)12-19(28)11-21/h2,5-10,13,15-16,19,21-22H,3-4,11-12,14,28H2,1H3,(H,30,32,33)	OTRFBZXWQCEWOV-UHFFFAOYSA-N	684565	US12030897, Example 8	Epidermal growth factor receptor	Homo sapiens		 385							US Patent		10.7270/Q2W66R3G		aid1963935	US12030897	Chen, KX; Jiang, F; Chen, X; Zhang, L; Chen, Z; Yu, Y; Zhou, K; Hu, B; Xie, C; Chen, S	7/9/2024	10/16/2024	Medshine Discovery	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=684565	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=684565&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			157303770	503273942							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502302	CC(C)n1c(=O)cc(N2CC(CS(C)(=O)=O)C2)c2cnc(Cc3ccnc(N4CCC(O)CC4)n3)cc21	InChI=1S/C26H34N6O4S/c1-17(2)32-24-11-20(10-19-4-7-27-26(29-19)30-8-5-21(33)6-9-30)28-13-22(24)23(12-25(32)34)31-14-18(15-31)16-37(3,35)36/h4,7,11-13,17-18,21,33H,5-6,8-10,14-16H2,1-3H3	HXBAWNZGHSJIHF-UHFFFAOYSA-N	727097	US20250092017, Compound P13	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727097	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727097&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509942	518297021							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502306	CC(C)n1c(=O)cc(N2CC(CS(C)(=O)=O)C2)c2cnc(Cc3ccnc(N4CCC(O)C(F)C4)n3)cc21	InChI=1S/C26H33FN6O4S/c1-16(2)33-23-9-19(8-18-4-6-28-26(30-18)31-7-5-24(34)21(27)14-31)29-11-20(23)22(10-25(33)35)32-12-17(13-32)15-38(3,36)37/h4,6,9-11,16-17,21,24,34H,5,7-8,12-15H2,1-3H3	ZNZFNVPOENRKNI-UHFFFAOYSA-N	727098	US20250092017, Compound P14	Epidermal growth factor receptor	Homo sapiens		 80.7							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727098	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727098&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509943	518297022							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502310	CNC(=O)CN1CC(c2ccc(C(C)C)c3cc(Nc4ccnc(N5CCC(O)C(F)C5)n4)ncc23)C1	InChI=1S/C27H34FN7O2/c1-16(2)18-4-5-19(17-12-34(13-17)15-26(37)29-3)21-11-31-25(10-20(18)21)32-24-6-8-30-27(33-24)35-9-7-23(36)22(28)14-35/h4-6,8,10-11,16-17,22-23,36H,7,9,12-15H2,1-3H3,(H,29,37)(H,30,31,32,33)	MEBOCUKKKFPTGS-UHFFFAOYSA-N	727099	US20250092017, Compound P15	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727099	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727099&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170048926	518297023							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502314	CC(C)c1cc(C#N)c(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C27H32FN7O3S/c1-16(2)19-8-18(10-29)26(35-12-17(13-35)15-39(3,37)38)21-11-31-25(9-20(19)21)32-24-4-6-30-27(33-24)34-7-5-23(36)22(28)14-34/h4,6,8-9,11,16-17,22-23,36H,5,7,12-15H2,1-3H3,(H,30,31,32,33)	NQYWAEHDMJYLFM-UHFFFAOYSA-N	727100	US20250092017, Compound P16	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727100	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727100&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170050459	518297024							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502317	CC(C)c1ccc(N2CC(CS(C)=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C26H33FN6O2S/c1-16(2)18-4-5-22(33-12-17(13-33)15-36(3)35)20-11-29-25(10-19(18)20)30-24-6-8-28-26(31-24)32-9-7-23(34)21(27)14-32/h4-6,8,10-11,16-17,21,23,34H,7,9,12-15H2,1-3H3,(H,28,29,30,31)	PDUZFFJYMRXNEG-UHFFFAOYSA-N	727101	US20250092017, Compound P17	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727101	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727101&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170050500	518297025							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502321	CC(C)c1ccc(N2CC(c3cscn3)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C27H30FN7OS/c1-16(2)18-3-4-23(35-11-17(12-35)22-14-37-15-31-22)20-10-30-26(9-19(18)20)32-25-5-7-29-27(33-25)34-8-6-24(36)21(28)13-34/h3-5,7,9-10,14-17,21,24,36H,6,8,11-13H2,1-2H3,(H,29,30,32,33)	FNKAATIFCKTGEE-UHFFFAOYSA-N	727102	US20250092017, Compound P18	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727102	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727102&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170050502	518297026							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502324	CC(C)n1c(=O)nc(N2CC(CS(C)(=O)=O)C2)c2cnc(Cc3ccnc(N4CC[C@H](O)[C@H](F)C4)n3)cc21	InChI=1S/C25H32FN7O4S/c1-15(2)33-21-9-18(8-17-4-6-27-24(29-17)31-7-5-22(34)20(26)13-31)28-10-19(21)23(30-25(33)35)32-11-16(12-32)14-38(3,36)37/h4,6,9-10,15-16,20,22,34H,5,7-8,11-14H2,1-3H3	CWAQYMJCHAJPPX-UHFFFAOYSA-N	727103	US20250092017, Compound P19	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727103	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727103&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509944	518297027							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502328	CC(C)n1c(=O)nc(N2CC(CS(C)(=O)=O)C2)c2cnc(Cc3ccnc(N4CC[C@@H](O)[C@H](F)C4)n3)cc21	InChI=1S/C25H32FN7O4S/c1-15(2)33-21-9-18(8-17-4-6-27-24(29-17)31-7-5-22(34)20(26)13-31)28-10-19(21)23(30-25(33)35)32-11-16(12-32)14-38(3,36)37/h4,6,9-10,15-16,20,22,34H,5,7-8,11-14H2,1-3H3	CWAQYMJCHAJPPX-UHFFFAOYSA-N	727104	US20250092017, Compound P20	Epidermal growth factor receptor	Homo sapiens		 90.9							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727104	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727104&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509945	518297028							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502332	CC(C)c1ccc(N2CC(NS(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C25H32FN7O3S/c1-15(2)17-4-5-21(33-12-16(13-33)31-37(3,35)36)19-11-28-24(10-18(17)19)29-23-6-8-27-25(30-23)32-9-7-22(34)20(26)14-32/h4-6,8,10-11,15-16,20,22,31,34H,7,9,12-14H2,1-3H3,(H,27,28,29,30)	AVBJGKFEGBSPCI-UHFFFAOYSA-N	727105	US20250092017, Compound P21	Epidermal growth factor receptor	Homo sapiens		 8.40							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727105&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170048929	518297029							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502336	CC(C)c1ccc(N2CC(c3ccc[nH]c3=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C29H32FN7O2/c1-17(2)19-5-6-24(37-14-18(15-37)20-4-3-9-31-28(20)39)22-13-33-27(12-21(19)22)34-26-7-10-32-29(35-26)36-11-8-25(38)23(30)16-36/h3-7,9-10,12-13,17-18,23,25,38H,8,11,14-16H2,1-2H3,(H,31,39)(H,32,33,34,35)	AETWWHLQYRFBBC-UHFFFAOYSA-N	727106	US20250092017, Compound P22	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727106	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727106&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170050555	518297030							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502340	CC(C)c1ccc(N2CC(NS(=O)(=O)C3CC3)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C27H34FN7O3S/c1-16(2)19-5-6-23(35-13-17(14-35)33-39(37,38)18-3-4-18)21-12-30-26(11-20(19)21)31-25-7-9-29-27(32-25)34-10-8-24(36)22(28)15-34/h5-7,9,11-12,16-18,22,24,33,36H,3-4,8,10,13-15H2,1-2H3,(H,29,30,31,32)	RTIDHSJIPDRXCS-UHFFFAOYSA-N	727107	US20250092017, Compound P23	Epidermal growth factor receptor	Homo sapiens		 33.8							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727107	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727107&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170048930	518297031							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502344	COC1CCN(c2nccc(Cc3cc4c(cn3)c(N3CC(CS(C)(=O)=O)C3)cc(=O)n4C(C)C)n2)CC1F	InChI=1S/C27H35FN6O4S/c1-17(2)34-24-10-20(9-19-5-7-29-27(31-19)32-8-6-25(38-3)22(28)15-32)30-12-21(24)23(11-26(34)35)33-13-18(14-33)16-39(4,36)37/h5,7,10-12,17-18,22,25H,6,8-9,13-16H2,1-4H3	RZQCQRZIQIBUTH-UHFFFAOYSA-N	727108	US20250092017, Compound P24	Epidermal growth factor receptor	Homo sapiens		 41.2							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727108	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727108&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509946	518297032							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502347	CC(C)c1ccc(N2C[C@H](NS(C)(=O)=O)[C@H]2C)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C26H34FN7O3S/c1-15(2)17-5-6-22(34-14-21(16(34)3)32-38(4,36)37)19-12-29-25(11-18(17)19)30-24-7-9-28-26(31-24)33-10-8-23(35)20(27)13-33/h5-7,9,11-12,15-16,20-21,23,32,35H,8,10,13-14H2,1-4H3,(H,28,29,30,31)	IEXQYJLNECRESC-UHFFFAOYSA-N	727109	US20250092017, Compound P25	Epidermal growth factor receptor	Homo sapiens		 5.10							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727109	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727109&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509947	518297033							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502351	CC(C)c1ccc(N2C[C@@H](NS(C)(=O)=O)[C@@H]2C)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C26H34FN7O3S/c1-15(2)17-5-6-22(34-14-21(16(34)3)32-38(4,36)37)19-12-29-25(11-18(17)19)30-24-7-9-28-26(31-24)33-10-8-23(35)20(27)13-33/h5-7,9,11-12,15-16,20-21,23,32,35H,8,10,13-14H2,1-4H3,(H,28,29,30,31)	IEXQYJLNECRESC-UHFFFAOYSA-N	727110	US20250092017, Compound P26	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727110	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727110&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509948	518297034							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502355	CC(C)c1ccc(N2CC(NS(=O)(=O)c3cccnc3)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C29H33FN8O3S/c1-18(2)21-5-6-25(38-15-19(16-38)36-42(40,41)20-4-3-9-31-13-20)23-14-33-28(12-22(21)23)34-27-7-10-32-29(35-27)37-11-8-26(39)24(30)17-37/h3-7,9-10,12-14,18-19,24,26,36,39H,8,11,15-17H2,1-2H3,(H,32,33,34,35)	MALCVSHWKIWHGY-UHFFFAOYSA-N	727111	US20250092017, Compound P28	Epidermal growth factor receptor	Homo sapiens		 64.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727111	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727111&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509949	518297035							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502359	COC1CCN(c2nccc(Nc3cc4c(C(C)C)ccc(N5CC(NS(C)(=O)=O)C5)c4cn3)n2)CC1F	InChI=1S/C26H34FN7O3S/c1-16(2)18-5-6-22(34-13-17(14-34)32-38(4,35)36)20-12-29-25(11-19(18)20)30-24-7-9-28-26(31-24)33-10-8-23(37-3)21(27)15-33/h5-7,9,11-12,16-17,21,23,32H,8,10,13-15H2,1-4H3,(H,28,29,30,31)	XTFSOIPXJQNXIJ-UHFFFAOYSA-N	727113	US20250092017, Compound P29	Epidermal growth factor receptor	Homo sapiens		 8.40							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727113	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727113&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509950	518297036							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502363	CC(C)c1ccc(N2CC(NS(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)(F)C4)n3)cc12	InChI=1S/C25H31F2N7O3S/c1-15(2)17-4-5-20(34-12-16(13-34)32-38(3,36)37)19-11-29-23(10-18(17)19)30-22-6-8-28-24(31-22)33-9-7-21(35)25(26,27)14-33/h4-6,8,10-11,15-16,21,32,35H,7,9,12-14H2,1-3H3,(H,28,29,30,31)	PAFIYXCHGABIBH-UHFFFAOYSA-N	727114	US20250092017, Compound P30	Epidermal growth factor receptor	Homo sapiens		 18.1							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727114	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727114&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170048986	518297037							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502367	CC(C)c1ccc(N2CC(N(C)S(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CC[C@@H](O)[C@@H](F)C4)n3)cc12	InChI=1S/C26H34FN7O3S/c1-16(2)18-5-6-22(34-13-17(14-34)32(3)38(4,36)37)20-12-29-25(11-19(18)20)30-24-7-9-28-26(31-24)33-10-8-23(35)21(27)15-33/h5-7,9,11-12,16-17,21,23,35H,8,10,13-15H2,1-4H3,(H,28,29,30,31)	YFAWCTSNBOENGX-UHFFFAOYSA-N	727115	US20250092017, Compound P39a	Epidermal growth factor receptor	Homo sapiens		 9.40							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727115	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727115&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170048993	518297038							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502371	CC(C)c1ccc(N2CC(NS(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(C)(F)C4)n3)cc12	InChI=1S/C26H34FN7O3S/c1-16(2)18-5-6-21(34-13-17(14-34)32-38(4,36)37)20-12-29-24(11-19(18)20)30-23-7-9-28-25(31-23)33-10-8-22(35)26(3,27)15-33/h5-7,9,11-12,16-17,22,32,35H,8,10,13-15H2,1-4H3,(H,28,29,30,31)	IXBGIQNJUNZUIJ-UHFFFAOYSA-N	727116	US20250092017, Compound P45	Epidermal growth factor receptor	Homo sapiens		 20.7							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727116	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727116&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049056	518297039							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502375	CC(C)c1ccc(N2CC(NS(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(C)(F)C4)n3)cc12	InChI=1S/C26H34FN7O3S/c1-16(2)18-5-6-21(34-13-17(14-34)32-38(4,36)37)20-12-29-24(11-19(18)20)30-23-7-9-28-25(31-23)33-10-8-22(35)26(3,27)15-33/h5-7,9,11-12,16-17,22,32,35H,8,10,13-15H2,1-4H3,(H,28,29,30,31)	IXBGIQNJUNZUIJ-UHFFFAOYSA-N	727117	US20250092017, Compound P46	Epidermal growth factor receptor	Homo sapiens		 41.8							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727117	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727117&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049056	518297040							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502379	CC(C)c1ccc(N2CC(NS(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CCC(C)(O)C(F)C4)n3)cc12	InChI=1S/C26H34FN7O3S/c1-16(2)18-5-6-21(34-13-17(14-34)32-38(4,36)37)20-12-29-24(11-19(18)20)30-23-7-9-28-25(31-23)33-10-8-26(3,35)22(27)15-33/h5-7,9,11-12,16-17,22,32,35H,8,10,13-15H2,1-4H3,(H,28,29,30,31)	MWXZDHXQBYJACR-UHFFFAOYSA-N	727118	US20250092017, Compound P51	Epidermal growth factor receptor	Homo sapiens		 13.4							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727118	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727118&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049069	518297041							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502387	COc1cccc(-c2nccc(Nc3cc4c(C(C)C)ccc(N5CC(CS(C)(=O)=O)C5)c4cn3)n2)n1	InChI=1S/C27H30N6O3S/c1-17(2)19-8-9-23(33-14-18(15-33)16-37(4,34)35)21-13-29-25(12-20(19)21)31-24-10-11-28-27(32-24)22-6-5-7-26(30-22)36-3/h5-13,17-18H,14-16H2,1-4H3,(H,28,29,31,32)	JICBACWHLJFOMO-UHFFFAOYSA-N	727120	US20250092017, Compound H2	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727120	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727120&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049070	518297043							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502391	CC(C)c4ccc(N1CC(CS(C)(=O)=O)C1)c5cnc(Nc3ccnc(c2cn[nH]c2)n3)cc45	InChI=1S/C24H27N7O2S/c1-15(2)18-4-5-21(31-12-16(13-31)14-34(3,32)33)20-11-26-23(8-19(18)20)29-22-6-7-25-24(30-22)17-9-27-28-10-17/h4-11,15-16H,12-14H2,1-3H3,(H,27,28)(H,25,26,29,30)	CEUBWULQVUBWLI-UHFFFAOYSA-N	727121	US20250092017, Compound H3	Epidermal growth factor receptor	Homo sapiens		 11.7							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727121	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727121&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049071	518297044							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502395	CC(C)c1ccc(N2CC(CC(N)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5CC5)c4)n3)cc12	InChI=1S/C27H30N8O3S/c1-16(2)20-5-6-23(34-13-17(14-34)9-24(28)36)22-12-30-26(10-21(20)22)32-25-7-8-29-27(33-25)18-11-31-35(15-18)39(37,38)19-3-4-19/h5-8,10-12,15-17,19H,3-4,9,13-14H2,1-2H3,(H2,28,36)(H,29,30,32,33)	SJTGWNNPMWUUOM-UHFFFAOYSA-N	727122	US20250092017, Compound H4	Epidermal growth factor receptor	Homo sapiens		 6.10							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727122	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727122&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049073	518297045							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502399	CC(C)n1c(=O)cc(N2CC(CS(C)(=O)=O)C2)c2cnc(Cc3ccnc(-c4cnn(S(=O)(=O)C5CC5)c4)n3)cc21	InChI=1S/C27H31N7O5S2/c1-17(2)34-25-9-21(29-12-23(25)24(10-26(34)35)32-13-18(14-32)16-40(3,36)37)8-20-6-7-28-27(31-20)19-11-30-33(15-19)41(38,39)22-4-5-22/h6-7,9-12,15,17-18,22H,4-5,8,13-14,16H2,1-3H3	AAEBAUUJUYKCJB-UHFFFAOYSA-N	727123	US20250092017, Compound H5	Epidermal growth factor receptor	Homo sapiens		 10.2							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727123	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727123&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509951	518297046							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502403	CCCS(=O)(=O)n1cc(-c2nccc(Nc3cc4c(C(C)C)ccc(N5CC(CS(C)(=O)=O)C5)c4cn3)n2)cn1	InChI=1S/C27H33N7O4S2/c1-5-10-40(37,38)34-16-20(12-30-34)27-28-9-8-25(32-27)31-26-11-22-21(18(2)3)6-7-24(23(22)13-29-26)33-14-19(15-33)17-39(4,35)36/h6-9,11-13,16,18-19H,5,10,14-15,17H2,1-4H3,(H,28,29,31,32)	JHRWRFFSWONZAB-UHFFFAOYSA-N	727124	US20250092017, Compound H6	Epidermal growth factor receptor	Homo sapiens		 5.20							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727124	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727124&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049075	518297047							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502407	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(C)(=O)=O)c4)n3)cc12	InChI=1S/C25H29N7O4S2/c1-16(2)19-5-6-22(31-12-17(13-31)15-37(3,33)34)21-11-27-24(9-20(19)21)29-23-7-8-26-25(30-23)18-10-28-32(14-18)38(4,35)36/h5-11,14,16-17H,12-13,15H2,1-4H3,(H,26,27,29,30)	YMXYTOGEEALCCN-UHFFFAOYSA-N	727125	US20250092017, Compound H7	Epidermal growth factor receptor	Homo sapiens		 2.40							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727125	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727125&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049077	518297048							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502410	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(C)(=O)=O)c4)n3)cc12	InChI=1S/C25H29N7O4S2/c1-16(2)19-5-6-22(31-12-17(13-31)15-37(3,33)34)21-11-27-24(9-20(19)21)29-23-7-8-26-25(30-23)18-10-28-32(14-18)38(4,35)36/h5-11,14,16-17H,12-13,15H2,1-4H3,(H,26,27,29,30)	YMXYTOGEEALCCN-UHFFFAOYSA-N	727127	US20250092017, Compound H8	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727127	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727127&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049077	518297049							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502413	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5CCCCC5)c4)n3)cc12	InChI=1S/C30H37N7O4S2/c1-20(2)24-9-10-27(36-16-21(17-36)19-42(3,38)39)26-15-32-29(13-25(24)26)34-28-11-12-31-30(35-28)22-14-33-37(18-22)43(40,41)23-7-5-4-6-8-23/h9-15,18,20-21,23H,4-8,16-17,19H2,1-3H3,(H,31,32,34,35)	OIFBSYNNTIVJOE-UHFFFAOYSA-N	727128	US20250092017, Compound H9	Epidermal growth factor receptor	Homo sapiens		>100.0							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727128	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727128&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049078	518297050							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502416	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5CCOCC5)c4)n3)cc12	InChI=1S/C29H35N7O5S2/c1-19(2)23-4-5-26(35-15-20(16-35)18-42(3,37)38)25-14-31-28(12-24(23)25)33-27-6-9-30-29(34-27)21-13-32-36(17-21)43(39,40)22-7-10-41-11-8-22/h4-6,9,12-14,17,19-20,22H,7-8,10-11,15-16,18H2,1-3H3,(H,30,31,33,34)	ZWEJMVYPMMFULJ-UHFFFAOYSA-N	727129	US20250092017, Compound H10	Epidermal growth factor receptor	Homo sapiens		 30.3							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727129	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727129&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049079	518297051							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502420	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(CC(F)(F)F)c4)n3)cc12	InChI=1S/C26H28F3N7O2S/c1-16(2)19-4-5-22(35-11-17(12-35)14-39(3,37)38)21-10-31-24(8-20(19)21)33-23-6-7-30-25(34-23)18-9-32-36(13-18)15-26(27,28)29/h4-10,13,16-17H,11-12,14-15H2,1-3H3,(H,30,31,33,34)	HXYWVBVDRBBJKY-UHFFFAOYSA-N	727130	US20250092017, Compound H11	Epidermal growth factor receptor	Homo sapiens		 24.3							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727130	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727130&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049080	518297052							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502424	CC(C)c1ccc(N2C[C@H](CS(C)(=O)=O)[C@H]2C)c2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5CC5)c4)n3)cc12	InChI=1S/C28H33N7O4S2/c1-17(2)22-7-8-25(34-14-20(18(34)3)16-40(4,36)37)24-13-30-27(11-23(22)24)32-26-9-10-29-28(33-26)19-12-31-35(15-19)41(38,39)21-5-6-21/h7-13,15,17-18,20-21H,5-6,14,16H2,1-4H3,(H,29,30,32,33)	LVZDPWDFPHNDAH-UHFFFAOYSA-N	727131	US20250092017, Compound H12	Epidermal growth factor receptor	Homo sapiens		 1.90							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727131	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727131&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			167483689	518297053							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502428	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5CCC5)c4)n3)cc12	InChI=1S/C28H33N7O4S2/c1-18(2)22-7-8-25(34-14-19(15-34)17-40(3,36)37)24-13-30-27(11-23(22)24)32-26-9-10-29-28(33-26)20-12-31-35(16-20)41(38,39)21-5-4-6-21/h7-13,16,18-19,21H,4-6,14-15,17H2,1-3H3,(H,29,30,32,33)	DKCANLOGVGAXPP-UHFFFAOYSA-N	727132	US20250092017, Compound H13	Epidermal growth factor receptor	Homo sapiens		 11.4							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727132	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727132&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049143	518297054							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502432	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5(C)CC5)c4)n3)cc12	InChI=1S/C28H33N7O4S2/c1-18(2)21-5-6-24(34-14-19(15-34)17-40(4,36)37)23-13-30-26(11-22(21)23)32-25-7-10-29-27(33-25)20-12-31-35(16-20)41(38,39)28(3)8-9-28/h5-7,10-13,16,18-19H,8-9,14-15,17H2,1-4H3,(H,29,30,32,33)	XRCYTKMUZHFYTK-UHFFFAOYSA-N	727133	US20250092017, Compound H18	Epidermal growth factor receptor	Homo sapiens		 7.30							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727133	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727133&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170051414	518297055							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502436	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)N(C)C)c4)n3)cc12	InChI=1S/C26H32N8O4S2/c1-17(2)20-6-7-23(33-13-18(14-33)16-39(5,35)36)22-12-28-25(10-21(20)22)30-24-8-9-27-26(31-24)19-11-29-34(15-19)40(37,38)32(3)4/h6-12,15,17-18H,13-14,16H2,1-5H3,(H,27,28,30,31)	PJIWLBXHXKGYAS-UHFFFAOYSA-N	727134	US20250092017, Compound H19	Epidermal growth factor receptor	Homo sapiens		 7.40							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727134	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727134&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			170049147	518297056							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1502440	CC(C)c1ccc(N2CC(CS(C)(=O)=O)C2)c2cnc(Cc3ccnc(N4CCC(O)C(F)C4)n3)cc12	InChI=1S/C27H34FN5O3S/c1-17(2)21-4-5-25(33-13-18(14-33)16-37(3,35)36)23-12-30-20(11-22(21)23)10-19-6-8-29-27(31-19)32-9-7-26(34)24(28)15-32/h4-6,8,11-12,17-18,24,26,34H,7,9-10,13-16H2,1-3H3	AWCJEYMYZGLONF-UHFFFAOYSA-N	727135	WO2021133809, Control A::US20250092017, Compound Control A	Epidermal growth factor receptor	Homo sapiens		 30.2							US Patent		10.7270/Q2X35305		aid1804121	US10544151	Liu, B; Gao, F; Yuan, S; Zhao, H; Peng, X; Liu, C; Shao, N; Guo, Y; Wu, Y; Wu, Z	3/20/2025	7/25/2025	Suzhou Puhe Biopharma Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=727135	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=727135&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176509952	518297057							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1529143	C=CC(=O)NC1=CC(Nc2nccc(N3CC(CN(C)C)C(c4ccccc4)=N3)n2)C(OC)N=C1N1CCOCC1	InChI=1S/C29H37N9O3/c1-5-25(39)31-22-17-23(28(40-4)34-27(22)37-13-15-41-16-14-37)32-29-30-12-11-24(33-29)38-19-21(18-36(2)3)26(35-38)20-9-7-6-8-10-20/h5-12,17,21,23,28H,1,13-16,18-19H2,2-4H3,(H,31,39)(H,30,32,33)	UZNLYSOTLMPTED-UHFFFAOYSA-N	743993	US12312329, Example T-1	Epidermal growth factor receptor	Homo sapiens		 1.29							US Patent		10.7270/Q24Q80J9			US12312329	Wang, Y; Li, H	5/27/2025	9/21/2025	Shenzhen Targetrx	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=743993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=743993&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			176734222	518816732							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1529145	C=CC(=O)Nc1cc(Nc2ncc(F)c(-n3cc(CN(C)C)c(-c4ccccc4)n3)n2)c(OC)nc1N1CCOCC1	InChI=1S/C29H32FN9O3/c1-5-24(40)32-22-15-23(28(41-4)34-27(22)38-11-13-42-14-12-38)33-29-31-16-21(30)26(35-29)39-18-20(17-37(2)3)25(36-39)19-9-7-6-8-10-19/h5-10,15-16,18H,1,11-14,17H2,2-4H3,(H,32,40)(H,31,33,35)	VOMZDVUUWNOUPS-UHFFFAOYSA-N	743994	US12312329, Example T-2	Epidermal growth factor receptor	Homo sapiens		 3.33							US Patent		10.7270/Q24Q80J9			US12312329	Wang, Y; Li, H	5/27/2025	9/21/2025	Shenzhen Targetrx	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=743994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=743994&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			153087608	518816733							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1529147	C=CC(=O)Nc1cc(Nc2ncc(C)c(-n3cc(CN(C)C)c(-c4ccccc4)n3)n2)c(OC)nc1N1CCOCC1	InChI=1S/C30H35N9O3/c1-6-25(40)32-23-16-24(29(41-5)34-28(23)38-12-14-42-15-13-38)33-30-31-17-20(2)27(35-30)39-19-22(18-37(3)4)26(36-39)21-10-8-7-9-11-21/h6-11,16-17,19H,1,12-15,18H2,2-5H3,(H,32,40)(H,31,33,35)	MHSAVXFFDNRHFG-UHFFFAOYSA-N	743995	US12312329, Example T-3	Epidermal growth factor receptor	Homo sapiens		 6.29							US Patent		10.7270/Q24Q80J9			US12312329	Wang, Y; Li, H	5/27/2025	9/21/2025	Shenzhen Targetrx	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=743995	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=743995&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154956518	518816734							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1529149	C=CC(=O)Nc1cc(Nc2nccc(-n3cc(CN(C)C)c(-c4ccccc4)n3)n2)c(OC(C)C)nc1N1CCOCC1	InChI=1S/C31H37N9O3/c1-6-27(41)33-24-18-25(30(43-21(2)3)36-29(24)39-14-16-42-17-15-39)34-31-32-13-12-26(35-31)40-20-23(19-38(4)5)28(37-40)22-10-8-7-9-11-22/h6-13,18,20-21H,1,14-17,19H2,2-5H3,(H,33,41)(H,32,34,35)	UGZRBLGHWVPTCD-UHFFFAOYSA-N	743996	US12312329, Example T-4	Epidermal growth factor receptor	Homo sapiens		 1.98							US Patent		10.7270/Q24Q80J9			US12312329	Wang, Y; Li, H	5/27/2025	9/21/2025	Shenzhen Targetrx	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=743996	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=743996&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154956353	518816735							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1529151	C=CC(=O)Nc1cc(Nc2nccc(-n3cc(CN(C)C)c(-c4ccccc4)n3)n2)c(OC)nc1N1CCOCC1	InChI=1S/C29H33N9O3/c1-5-25(39)31-22-17-23(28(40-4)34-27(22)37-13-15-41-16-14-37)32-29-30-12-11-24(33-29)38-19-21(18-36(2)3)26(35-38)20-9-7-6-8-10-20/h5-12,17,19H,1,13-16,18H2,2-4H3,(H,31,39)(H,30,32,33)	URBNJQGSPKRPDH-UHFFFAOYSA-N	743997	US12312329, Example T-7	Epidermal growth factor receptor	Homo sapiens		 0.550							US Patent		10.7270/Q24Q80J9			US12312329	Wang, Y; Li, H	5/27/2025	9/21/2025	Shenzhen Targetrx	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=743997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=743997&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			154956472	518816736							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50038503	[H][C@]12C[C@]3([H])C[C@]([H])(C1)CC(CCOC(=O)c1cc(NCc4cc(O)ccc4O)ccc1O)(C2)C3 |TLB:8:6:34:1.33.2,8:1:34:6.9.5,THB:2:3:9:1.33.8,2:1:9:3.34.5|	InChI=1S/C26H31NO5/c28-21-2-4-23(29)19(10-21)15-27-20-1-3-24(30)22(11-20)25(31)32-6-5-26-12-16-7-17(13-26)9-18(8-16)14-26/h1-4,10-11,16-18,27-30H,5-9,12-15H2	UKUPIEIGJLWQAX-UHFFFAOYSA-N	50453568	CHEMBL169885	Epidermal growth factor receptor	Homo sapiens		 1250							ChEMBL	10.1021/jm00032a020	10.7270/Q2QV3KJ3	8145236			Chen, H; Boiziau, J; Parker, F; Mailliet, P; Commerçon, A; Tocque, B; Le Pecq, JB; Roques, BP; Garbay, C	3/18/1994	11/10/2009	University of Paris	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453568	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453568&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			10455755	225146004		CHEMBL169885					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50695132	Clc1cccc(Nc2ncnc3ccc(NC(=O)C4CCC5(CC4)OOC4(OO5)C5CC6CC(C5)CC4C6)cc23)c1 |TLB:34:33:26.30.29:37,34:29:32.33.35:37,THB:26:29:32:35.36.37,26:36:32:30.34.29|	InChI=1S/C31H33ClN4O5/c32-23-2-1-3-24(15-23)35-28-26-16-25(4-5-27(26)33-17-34-28)36-29(37)20-6-8-30(9-7-20)38-40-31(41-39-30)21-11-18-10-19(13-21)14-22(31)12-18/h1-5,15-22H,6-14H2,(H,36,37)(H,33,34,35)	DHVYOQJAIUYUNV-UHFFFAOYSA-N	50233353	CHEMBL4067373	Epidermal growth factor receptor	Homo sapiens		 380							ChEMBL	10.1016/j.bmcl.2017.02.023	10.7270/Q2CF9SBX	28236592			Yang, J; Tu, Z; Xu, X; Luo, J; Yan, X; Ran, C; Mao, X; Ding, K; Qiao, C	3/15/2017	6/1/2019	Soochow University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233353&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137632485	384583719		CHEMBL4067373					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50695133	Clc1cccc(Nc2ncnc3ccc(NC(=O)C4CCC5(CC4)OOC4(O5)C5CC6CC(C5)CC4C6)cc23)c1 |TLB:33:32:26.29.28:36,33:28:31.32.34:36,THB:26:28:31:34.35.36,26:35:31:29.33.28,25:26:31.32.34:36,27:26:31.32.34:36,(45.71,-.56,;46.5,-1.88,;48.05,-1.86,;48.83,-3.19,;48.07,-4.53,;46.53,-4.54,;45.77,-5.88,;46.56,-7.21,;48.09,-7.19,;48.88,-8.52,;48.12,-9.86,;46.58,-9.87,;45.82,-11.21,;44.28,-11.22,;43.51,-9.89,;41.97,-9.9,;41.19,-8.57,;41.96,-7.23,;39.65,-8.58,;38.88,-7.24,;37.34,-7.25,;36.55,-8.57,;37.34,-9.92,;38.89,-9.92,;36.15,-7.08,;34.6,-7,;34.05,-8.45,;35.26,-9.42,;33.03,-9.58,;31.75,-8.92,;31.08,-7.68,;29.34,-7.84,;30.74,-8.52,;31.43,-9.87,;31.79,-7.32,;33.38,-7.09,;32.06,-6.56,;44.26,-8.55,;45.8,-8.54,;45.75,-3.22,)|	InChI=1S/C31H33ClN4O4/c32-23-2-1-3-24(15-23)35-28-26-16-25(4-5-27(26)33-17-34-28)36-29(37)20-6-8-30(9-7-20)38-31(40-39-30)21-11-18-10-19(13-21)14-22(31)12-18/h1-5,15-22H,6-14H2,(H,36,37)(H,33,34,35)	ZUYTYXOKIWZBIE-UHFFFAOYSA-N	50233354	CHEMBL4094823	Epidermal growth factor receptor	Homo sapiens		 32							ChEMBL	10.1016/j.bmcl.2017.02.023	10.7270/Q2CF9SBX	28236592			Yang, J; Tu, Z; Xu, X; Luo, J; Yan, X; Ran, C; Mao, X; Ding, K; Qiao, C	3/15/2017	6/1/2019	Soochow University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233354&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137653327	384583720		CHEMBL4094823					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50695134	Clc1cccc(Nc2ncnc3ccc(NC(=O)C4CCC5(CC4)OCC4(OO5)C5CC6CC(C5)CC4C6)cc23)c1 |TLB:27:26:32.37.31:35,30:31:35:34.26.29,THB:26:36:32:30.34.29,26:29:32:37.36.35,30:29:32.37.31:35|	InChI=1S/C32H35ClN4O4/c33-24-2-1-3-25(15-24)36-29-27-16-26(4-5-28(27)34-18-35-29)37-30(38)21-6-8-31(9-7-21)39-17-32(41-40-31)22-11-19-10-20(13-22)14-23(32)12-19/h1-5,15-16,18-23H,6-14,17H2,(H,37,38)(H,34,35,36)	AYLLCQPKGAMNHX-UHFFFAOYSA-N	50233355	CHEMBL4082840	Epidermal growth factor receptor	Homo sapiens		 95							ChEMBL	10.1016/j.bmcl.2017.02.023	10.7270/Q2CF9SBX	28236592			Yang, J; Tu, Z; Xu, X; Luo, J; Yan, X; Ran, C; Mao, X; Ding, K; Qiao, C	3/15/2017	6/1/2019	Soochow University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233355&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137646967	384583721		CHEMBL4082840					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50695135	Clc1cccc(Nc2ccnc3ccc(NC(=O)C4CCC5(CC4)OCC4(OO5)C5CC6CC(C5)CC4C6)cc23)c1 |TLB:34:33:26.30.29:37,34:29:32.33.35:37,THB:26:29:32:35.36.37,26:36:32:30.34.29,27:26:32.33.35:37|	InChI=1S/C33H36ClN3O4/c34-25-2-1-3-26(17-25)36-30-8-11-35-29-5-4-27(18-28(29)30)37-31(38)22-6-9-32(10-7-22)39-19-33(41-40-32)23-13-20-12-21(15-23)16-24(33)14-20/h1-5,8,11,17-18,20-24H,6-7,9-10,12-16,19H2,(H,35,36)(H,37,38)	JDUVITZLJUDMKX-UHFFFAOYSA-N	50233356	CHEMBL4091166	Epidermal growth factor receptor	Homo sapiens		 169							ChEMBL	10.1016/j.bmcl.2017.02.023	10.7270/Q2CF9SBX	28236592			Yang, J; Tu, Z; Xu, X; Luo, J; Yan, X; Ran, C; Mao, X; Ding, K; Qiao, C	3/15/2017	6/1/2019	Soochow University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233356&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137642384	384583722		CHEMBL4091166					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50695136	OC(=O)C1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3 |TLB:19:18:22:15.14.11,19:14:17.18.20:22,THB:11:14:17:20.21.22,11:21:17:15.19.14,(4.51,-14.13,;3.75,-12.79,;4.53,-11.45,;2.2,-12.78,;1.42,-14.11,;-.11,-14.1,;-.88,-12.77,;-.11,-11.44,;1.43,-11.44,;-1.66,-11.42,;-3.2,-11.43,;-3.98,-12.77,;-3.2,-14.12,;-1.64,-14.12,;-4.76,-14.1,;-6.15,-13.69,;-7.06,-12.6,;-8.74,-13.11,;-7.22,-13.5,;-6.28,-14.69,;-6.43,-12.12,;-4.9,-11.57,;-6.31,-11.3,)|	InChI=1S/C17H24O6/c18-15(19)12-1-3-16(4-2-12)20-22-17(23-21-16)13-6-10-5-11(8-13)9-14(17)7-10/h10-14H,1-9H2,(H,18,19)	QLBXWPYRCIWKCQ-UHFFFAOYSA-N	50233357	CHEMBL1830034	Epidermal growth factor receptor	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2017.02.023	10.7270/Q2CF9SBX	28236592			Yang, J; Tu, Z; Xu, X; Luo, J; Yan, X; Ran, C; Mao, X; Ding, K; Qiao, C	3/15/2017	6/1/2019	Soochow University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233357	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233357&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			56660000	384583723		CHEMBL1830034					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
50695139	Clc1cccc(Nc2ccnc3ccc(NC(=O)C4CCC5(CC4)OOC4(O5)C5CC6CC(C5)CC4C6)cc23)c1 |TLB:29:30:34:33.26.28,27:26:34:36.30.31,27:26:29.36.30:33.34.32,THB:29:28:34:36.30.31,25:26:34:36.30.31,25:26:29.36.30:33.34.32,31:30:26:33.34.32,31:32:26:29.36.30|	InChI=1S/C32H34ClN3O4/c33-24-2-1-3-25(17-24)35-29-8-11-34-28-5-4-26(18-27(28)29)36-30(37)21-6-9-31(10-7-21)38-32(40-39-31)22-13-19-12-20(15-22)16-23(32)14-19/h1-5,8,11,17-23H,6-7,9-10,12-16H2,(H,34,35)(H,36,37)	VTHMIYYUFBULTE-UHFFFAOYSA-N	50233358	CHEMBL4088200	Epidermal growth factor receptor	Homo sapiens		 177							ChEMBL	10.1016/j.bmcl.2017.02.023	10.7270/Q2CF9SBX	28236592			Yang, J; Tu, Z; Xu, X; Luo, J; Yan, X; Ran, C; Mao, X; Ding, K; Qiao, C	3/15/2017	6/1/2019	Soochow University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233358&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			137643437	384583724		CHEMBL4088200					1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51127230	O=C(N\N=C1/CC2(CCCCC2)Oc2c1ccc1ccccc21)C1C2CC3CC(C2)CC1C3 |TLB:32:31:29:25.26.27,THB:27:26:23:30.28.29,27:28:23:25.32.26,1:23:29:25.26.27,32:26:23.31.30:29,(33.82,-4.03,;33.82,-5.57,;35.16,-6.34,;36.49,-5.57,;37.83,-6.33,;37.83,-7.88,;39.16,-8.64,;37.83,-9.4,;37.82,-10.94,;39.14,-11.72,;40.48,-10.95,;40.49,-9.41,;40.51,-7.87,;40.49,-6.33,;39.15,-5.56,;39.16,-4.01,;40.49,-3.24,;41.83,-4.01,;43.15,-3.23,;44.49,-3.99,;44.5,-5.54,;43.16,-6.32,;41.83,-5.55,;32.49,-6.34,;31.27,-7.59,;29.96,-7.08,;28.55,-7.4,;28.51,-8.93,;29.9,-9.53,;31.25,-9.08,;30.96,-8.32,;30.99,-6.73,;29.59,-6.14,)|	InChI=1S/C29H34N2O2/c32-28(26-21-13-18-12-19(15-21)16-22(26)14-18)31-30-25-17-29(10-4-1-5-11-29)33-27-23-7-3-2-6-20(23)8-9-24(25)27/h2-3,6-9,18-19,21-22,26H,1,4-5,10-17H2,(H,31,32)	SGZWKWDDCXXCAG-UHFFFAOYSA-N	50462234	CHEMBL4241486	Epidermal growth factor receptor	Homo sapiens		 1200							ChEMBL	10.1016/j.ejmech.2018.03.001	10.7270/Q26D5WNS	29549841			Abdelatef, SA; El-Saadi, MT; Amin, NH; Abdelazeem, AH; Omar, HA; Abdellatif, KRA	4/25/2018	8/17/2020	Beni-Suef University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462234	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462234&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			145983757	433929499							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51487266	Oc1ccc(F)cc1C(N1Cc2ccccc2C1=O)c1nc(=O)c2ccccc2[nH]1	InChI=1S/C23H16FN3O3/c24-14-9-10-19(28)17(11-14)20(27-12-13-5-1-2-6-15(13)23(27)30)21-25-18-8-4-3-7-16(18)22(29)26-21/h1-11,20,28H,12H2,(H,25,26,29)	SDRVSRIKUIYXKQ-UHFFFAOYSA-N	50599337	CHEMBL5206476	Epidermal growth factor receptor	Homo sapiens		 5300							ChEMBL		10.7270/Q2QF8XXX	34323489			Shaikh, M; Shinde, Y; Pawara, R; Noolvi, M; Surana, S; Ahmad, I; Patel, H	1/27/2022	6/23/2023	H. R. Patel Institute of Pharmaceutical Education and Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50599337	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50599337&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			168294895	482610189							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51487267	O=C(Nc1nccs1)C(N1Cc2ccc(cc2C1=O)-c1ccc2[nH]ccc2c1)c1ccccc1	InChI=1S/C27H20N4O2S/c32-25(30-27-29-12-13-34-27)24(17-4-2-1-3-5-17)31-16-21-7-6-19(15-22(21)26(31)33)18-8-9-23-20(14-18)10-11-28-23/h1-15,24,28H,16H2,(H,29,30,32)	GRSCCESMUDSCTN-UHFFFAOYSA-N	50599338	CHEMBL5193027	Epidermal growth factor receptor	Homo sapiens		 15							ChEMBL		10.7270/Q2QF8XXX	34323489			Shaikh, M; Shinde, Y; Pawara, R; Noolvi, M; Surana, S; Ahmad, I; Patel, H	1/27/2022	6/23/2023	H. R. Patel Institute of Pharmaceutical Education and Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50599338	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50599338&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			135351534	482610190							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51555426	Cc1sc([Se]c2sc(C)c(c2C(=O)NC(CO)C(=O)N2CCCC2)-c2cccc(Br)c2)c(C(=O)NC(CO)C(=O)N2CCCC2)c1-c1cccc(Br)c1	InChI=1S/C38H40Br2N4O6S2Se/c1-21-29(23-9-7-11-25(39)17-23)31(33(47)41-27(19-45)35(49)43-13-3-4-14-43)37(51-21)53-38-32(30(22(2)52-38)24-10-8-12-26(40)18-24)34(48)42-28(20-46)36(50)44-15-5-6-16-44/h7-12,17-18,27-28,45-46H,3-6,13-16,19-20H2,1-2H3,(H,41,47)(H,42,48)	TWKFVCXLFZPWDA-UHFFFAOYSA-N	50625808	CHEMBL5439652	Epidermal growth factor receptor	Homo sapiens		 94							ChEMBL		10.7270/Q2P84H9B	38107169			Makhal, PN; Sood, A; Shaikh, AS; Dayare, LN; Khatri, DK; Rao Kaki, V	12/13/2023	12/18/2024	National Institute of Pharmaceutical Education and Research (NIPER)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50625808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50625808&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			172471363	505043780							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51555427	Cc1sc([Se]c2sc(C)c(c2C(=O)NC(CO)C(=O)N2CCCC2)-c2cccc(Cl)c2)c(C(=O)NC(CO)C(=O)N2CCCC2)c1-c1cccc(Cl)c1	InChI=1S/C38H40Cl2N4O6S2Se/c1-21-29(23-9-7-11-25(39)17-23)31(33(47)41-27(19-45)35(49)43-13-3-4-14-43)37(51-21)53-38-32(30(22(2)52-38)24-10-8-12-26(40)18-24)34(48)42-28(20-46)36(50)44-15-5-6-16-44/h7-12,17-18,27-28,45-46H,3-6,13-16,19-20H2,1-2H3,(H,41,47)(H,42,48)	BOSZCJUMGAKJHO-UHFFFAOYSA-N	50625809	CHEMBL5395404	Epidermal growth factor receptor	Homo sapiens		 727							ChEMBL		10.7270/Q2P84H9B	38107169			Makhal, PN; Sood, A; Shaikh, AS; Dayare, LN; Khatri, DK; Rao Kaki, V	12/13/2023	12/18/2024	National Institute of Pharmaceutical Education and Research (NIPER)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50625809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50625809&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			172444275	505043781							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51555428	CC(NC(=O)c1c([Se]c2sc(C)c(c2C(=O)NC(C)C(=O)N2CCCC2)-c2cccc(F)c2)sc(C)c1-c1cccc(F)c1)C(=O)N1CCCC1	InChI=1S/C38H40F2N4O4S2Se/c1-21(35(47)43-15-5-6-16-43)41-33(45)31-29(25-11-9-13-27(39)19-25)23(3)49-37(31)51-38-32(30(24(4)50-38)26-12-10-14-28(40)20-26)34(46)42-22(2)36(48)44-17-7-8-18-44/h9-14,19-22H,5-8,15-18H2,1-4H3,(H,41,45)(H,42,46)	MHCHEXSMXOLRBL-UHFFFAOYSA-N	50625810	CHEMBL5425169	Epidermal growth factor receptor	Homo sapiens		 835							ChEMBL		10.7270/Q2P84H9B	38107169			Makhal, PN; Sood, A; Shaikh, AS; Dayare, LN; Khatri, DK; Rao Kaki, V	12/13/2023	12/18/2024	National Institute of Pharmaceutical Education and Research (NIPER)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50625810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50625810&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			172460155	505043782							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51594051	CCCNc1nc2oc(C)c(C(=O)NNC(=O)c3cc4ccccc4oc3=O)c2c(=O)n1-c1ccccc1	InChI=1S/C27H23N5O6/c1-3-13-28-27-29-24-21(25(35)32(27)17-10-5-4-6-11-17)20(15(2)37-24)23(34)31-30-22(33)18-14-16-9-7-8-12-19(16)38-26(18)36/h4-12,14H,3,13H2,1-2H3,(H,28,29)(H,30,33)(H,31,34)	CXPJUIJCTVGIEZ-UHFFFAOYSA-N	50641845	CHEMBL5569412	Epidermal growth factor receptor	Homo sapiens		 1530							ChEMBL		10.7270/Q2JW8KJS	38784474			Wang, T; Gao, Y; Wu, F; Luo, L; Ma, J; Hu, Y	//0	10/12/2025	Hubei University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50641845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50641845&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			177381602	519667249							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51601360	C=CCn1c(SCC(=O)Nc2ccc(C(=O)/C=C/c3ccc(Cl)cc3)cc2)nnc1-c1cc(-c2ccccc2)nc2ccccc12	InChI=1S/C37H28ClN5O2S/c1-2-22-43-36(31-23-33(26-8-4-3-5-9-26)40-32-11-7-6-10-30(31)32)41-42-37(43)46-24-35(45)39-29-19-15-27(16-20-29)34(44)21-14-25-12-17-28(38)18-13-25/h2-21,23H,1,22,24H2,(H,39,45)	XJJSWJQPJABSJG-UHFFFAOYSA-N	50645268	CHEMBL5572677	Epidermal growth factor receptor	Homo sapiens		 1300							ChEMBL		10.7270/Q2959P7Z	39026636			Al-Wahaibi, LH; Youssif, BGM; Abou-Zied, HA; Bräse, S; Brown, AB; Tawfeek, HN; El-Sheref, EM	//0	10/12/2025	Princess Nourah bint Abdulrahman University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645268	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645268&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			162534280	519660670							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51601378	COc1cc(/C=N/c2c(C#N)nc3c(-c4cc(OC)c(OC)c(OC)c4)nc4ccccc4n23)cc(OC)c1OC	InChI=1S/C30H27N5O6/c1-36-22-11-17(12-23(37-2)27(22)40-5)16-32-29-20(15-31)34-30-26(33-19-9-7-8-10-21(19)35(29)30)18-13-24(38-3)28(41-6)25(14-18)39-4/h7-14,16H,1-6H3	CNHYDLAYRAMSHX-UHFFFAOYSA-N	50645281	CHEMBL5592391	Epidermal growth factor receptor	Homo sapiens		 211							ChEMBL		10.7270/Q21N85SW	39026650			Kumar, M; Patil, KT; Maity, P; Chatterjee, J; Singh, T; Joshi, G; Singh, S; Kumar, R	//0	10/12/2025	Central University of Punjab	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50645281	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50645281&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			177377188	519660683							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51613929	COCCOc1cc2ncnc(Nc3cccc(OS(=O)(=O)F)c3)c2cc1OCCOC	InChI=1S/C20H22FN3O7S/c1-27-6-8-29-18-11-16-17(12-19(18)30-9-7-28-2)22-13-23-20(16)24-14-4-3-5-15(10-14)31-32(21,25)26/h3-5,10-13H,6-9H2,1-2H3,(H,22,23,24)	DFSDQJWWAXBBHO-UHFFFAOYSA-N	50651045	CHEMBL5633067	Epidermal growth factor receptor	Homo sapiens		 0.009000							ChEMBL		10.7270/Q2P55T7H	37499291			Tang, G; Wang, W; Wang, X; Ding, K; Ngan, SC; Chen, JY; Sze, SK; Gao, L; Yuan, P; Lu, X; Yao, SQ	//0	10/13/2025	National University of Singapore	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50651045	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50651045&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			177371594	519643315							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
51613935	C=CC(=O)Oc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1	InChI=1S/C23H25N3O6/c1-4-22(27)32-17-7-5-6-16(12-17)26-23-18-13-20(30-10-8-28-2)21(31-11-9-29-3)14-19(18)24-15-25-23/h4-7,12-15H,1,8-11H2,2-3H3,(H,24,25,26)	XYRHGXCDOPLTBI-UHFFFAOYSA-N	50651046	CHEMBL5633759	Epidermal growth factor receptor	Homo sapiens		 171							ChEMBL		10.7270/Q2P55T7H	37499291			Tang, G; Wang, W; Wang, X; Ding, K; Ngan, SC; Chen, JY; Sze, SK; Gao, L; Yuan, P; Lu, X; Yao, SQ	//0	10/13/2025	National University of Singapore	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50651046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=520&target=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50651046&enzyme=Epidermal+growth+factor+receptor&column=ki&startPg=0&Increment=50&submit=Search			177371595	519643316							1	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA	3QWQ,1IVO,4UV7,9IPE,9IPD,9IPC,9IPB,9IPA,9IP9,9IP8,9IP7,4KRO,3B2V,4KRP,4UIP,1MOX,5WB8,5WB7,3GOP,8UKV,9P9U,7AEM,9GHV,9GHU,9GHT,9GHS,9GHR,7SI1,7B85,5EM8,5CAV,1M17,1M14,4TKS,7UKV,3VJO,8PNZ,7AEI,5UGB,4I23,1XKK,9QXN,9Q0S,9PMZ,9OU9,9OS6,9NM0,9NJN,9NJ7,9NIS,9NHW,9NGP,9MST,9MSS,9MSR,9KL4,9H47,9H46,9H42,9GL9,9GI9,9FRD,9DM8,8SC7,8G63,6VHP,6VHN,6VH4,6D8E,4ZAU,4WRG,4WKQ,4G5J,3W33,3W32,3W2S,3POZ,2RF9,2J6M,2J5F,2J5E,2ITY,2ITX,2ITW,2GS6,2GS2,7T4I,5FED,9FZS,9FZR,9BY6,9BY4,6JZ0,4JRV,4JR3,4JQ8,4JQ7,8PO0,4LI5,9U8C	Epidermal growth factor receptor	EGFR_HUMAN	P00533	O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5